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Search of human proteins with 40254442
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40254442 plexin B1 [Homo sapiens]
(2135 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194272180 plexin B1 [Homo sapiens] 4356 0.0
gi|40254442 plexin B1 [Homo sapiens] 4356 0.0
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 1264 0.0
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 1264 0.0
gi|149363636 plexin B2 [Homo sapiens] 988 0.0
gi|49355818 plexin A1 [Homo sapiens] 813 0.0
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 793 0.0
gi|113722116 plexin A2 [Homo sapiens] 788 0.0
gi|157694524 plexin D1 [Homo sapiens] 759 0.0
gi|59710104 plexin A3 [Homo sapiens] 751 0.0
gi|5032223 plexin C1 [Homo sapiens] 405 e-112
gi|157738643 plexin A4 isoform 2 [Homo sapiens] 119 2e-26
gi|157738647 plexin A4 isoform 3 [Homo sapiens] 119 4e-26
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 117 2e-25
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 105 4e-22
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s... 85 9e-16
gi|163965366 nascent polypeptide-associated complex alpha subuni... 79 4e-14
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 69 4e-11
gi|16306552 semaphorin Y [Homo sapiens] 69 5e-11
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 66 3e-10
gi|28872814 semaphorin 4G [Homo sapiens] 64 1e-09
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 64 2e-09
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 64 2e-09
gi|126116589 fibrocystin L [Homo sapiens] 63 3e-09
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 62 6e-09
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 62 6e-09
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 62 6e-09
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 62 6e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 6e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 62 6e-09
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 4356 bits (11297), Expect = 0.0
Identities = 2135/2135 (100%), Positives = 2135/2135 (100%)
Query: 1 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP
Sbjct: 1 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
Query: 61 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 120
GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE
Sbjct: 61 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 120
Query: 121 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 180
QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
Sbjct: 121 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 180
Query: 181 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 240
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ
Sbjct: 181 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 240
Query: 241 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 300
SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA
Sbjct: 241 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 300
Query: 301 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 360
APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
Sbjct: 301 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 360
Query: 361 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 420
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF
Sbjct: 361 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 420
Query: 421 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 480
LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA
Sbjct: 421 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 480
Query: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
Sbjct: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
Query: 541 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 600
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP
Sbjct: 541 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 600
Query: 601 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 660
RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC
Sbjct: 601 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 660
Query: 661 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720
THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
Sbjct: 661 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720
Query: 721 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780
ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP
Sbjct: 721 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780
Query: 781 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 840
SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD
Sbjct: 781 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 840
Query: 841 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 900
WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL
Sbjct: 841 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 900
Query: 901 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 960
WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE
Sbjct: 901 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 960
Query: 961 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 1020
VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY
Sbjct: 961 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 1020
Query: 1021 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1080
DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG
Sbjct: 1021 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1080
Query: 1081 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1140
PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA
Sbjct: 1081 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1140
Query: 1141 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200
TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG
Sbjct: 1141 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200
Query: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260
DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT
Sbjct: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260
Query: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320
KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS
Sbjct: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320
Query: 1321 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1380
QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL
Sbjct: 1321 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1380
Query: 1381 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP
Sbjct: 1381 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
Query: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL
Sbjct: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
Query: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG
Sbjct: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
Query: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI
Sbjct: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
Query: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1680
HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE
Sbjct: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1680
Query: 1681 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1740
TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL
Sbjct: 1681 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1740
Query: 1741 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1800
REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP
Sbjct: 1741 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1800
Query: 1801 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1860
RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE
Sbjct: 1801 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1860
Query: 1861 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1920
NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT
Sbjct: 1861 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1920
Query: 1921 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1980
RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS
Sbjct: 1921 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1980
Query: 1981 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 2040
LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR
Sbjct: 1981 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 2040
Query: 2041 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2100
DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD
Sbjct: 2041 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2100
Query: 2101 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL
Sbjct: 2101 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 4356 bits (11297), Expect = 0.0
Identities = 2135/2135 (100%), Positives = 2135/2135 (100%)
Query: 1 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP
Sbjct: 1 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
Query: 61 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 120
GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE
Sbjct: 61 GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 120
Query: 121 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 180
QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
Sbjct: 121 QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 180
Query: 181 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 240
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ
Sbjct: 181 IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 240
Query: 241 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 300
SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA
Sbjct: 241 SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 300
Query: 301 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 360
APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
Sbjct: 301 APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 360
Query: 361 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 420
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF
Sbjct: 361 NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 420
Query: 421 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 480
LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA
Sbjct: 421 LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 480
Query: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
Sbjct: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
Query: 541 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 600
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP
Sbjct: 541 PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 600
Query: 601 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 660
RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC
Sbjct: 601 RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 660
Query: 661 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720
THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
Sbjct: 661 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720
Query: 721 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780
ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP
Sbjct: 721 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780
Query: 781 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 840
SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD
Sbjct: 781 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 840
Query: 841 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 900
WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL
Sbjct: 841 WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 900
Query: 901 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 960
WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE
Sbjct: 901 WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 960
Query: 961 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 1020
VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY
Sbjct: 961 VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 1020
Query: 1021 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1080
DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG
Sbjct: 1021 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1080
Query: 1081 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1140
PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA
Sbjct: 1081 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1140
Query: 1141 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200
TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG
Sbjct: 1141 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200
Query: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260
DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT
Sbjct: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260
Query: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320
KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS
Sbjct: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320
Query: 1321 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1380
QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL
Sbjct: 1321 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1380
Query: 1381 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP
Sbjct: 1381 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
Query: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL
Sbjct: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
Query: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG
Sbjct: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
Query: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI
Sbjct: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
Query: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1680
HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE
Sbjct: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1680
Query: 1681 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1740
TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL
Sbjct: 1681 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1740
Query: 1741 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1800
REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP
Sbjct: 1741 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1800
Query: 1801 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1860
RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE
Sbjct: 1801 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1860
Query: 1861 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1920
NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT
Sbjct: 1861 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1920
Query: 1921 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1980
RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS
Sbjct: 1921 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1980
Query: 1981 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 2040
LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR
Sbjct: 1981 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 2040
Query: 2041 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2100
DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD
Sbjct: 2041 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2100
Query: 2101 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL
Sbjct: 2101 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 1264 bits (3272), Expect = 0.0
Identities = 690/1257 (54%), Positives = 842/1257 (66%), Gaps = 40/1257 (3%)
Query: 902 ELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEV 961
E++ G +CP VE + G L+PV E + L RNL F+ P C +EL G
Sbjct: 693 EVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELR 752
Query: 962 VVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYD 1021
+ A +E E D+ + CQ HQ Q EL V +++ + R+D+ L+V+LYD
Sbjct: 753 GLPATLE-ETAGDSGL-IHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYD 810
Query: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGP 1081
C++GH DCS CQ A GC+WC +P C C AV CPAP I +VEPLTGP
Sbjct: 811 CAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPG-AVELLCPAPSIDAVEPLTGP 869
Query: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
+GG +TI GSNLG+ DV V+VA PC + Y S+ +VC+T + G
Sbjct: 870 PEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPV 929
Query: 1142 AVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD 1201
V + + G+S F YQDP + S+ P GP+AGGT+LT+ G L TG + VG
Sbjct: 930 RVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGG--NTSAFVGG 987
Query: 1202 QPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTK 1261
QPC +L E + C T P+ P V V FG +R L F+YT +P + +A P+
Sbjct: 988 QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSA 1047
Query: 1262 SFLSGGREICVRGQNLDVVQTPRIRV------TVVSRMLQPSQGLGRRR----RVVPETA 1311
SF GGR I VRG LDVVQ P + V V + QP RR P+
Sbjct: 1048 SFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQAC 1107
Query: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTP 1371
LG Q C VNSS L+ CR+PA+P RV F LDN+ DFA+ +
Sbjct: 1108 IQLGGGLL--QCSTVCSVNSSSLLLCRSPAVPDRAHPQ--RVFFTLDNVQVDFASASGGQ 1163
Query: 1372 -FSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTL 1430
F Y+ +P L PL+ E P P+R KPG V VEGE L+L +SKEEV IG G C+VKTL
Sbjct: 1164 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1223
Query: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESP-GAFPVAA 1489
TR HLYCEPP P P + + LP+F VQMGN++ +LG VQY+ E P AFPV A
Sbjct: 1224 TRTHLYCEPPAHAPQPANGS------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1277
Query: 1490 QVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMT 1549
Q G+G+G ++L V+++ LMYR KSKQALRDY+KV +QLE+LE+ V D+C+KEFTDLMT
Sbjct: 1278 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1337
Query: 1550 EMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVP--ESRRPTVEQGLGQLS 1607
EMTDL+SDL GSGIPFLDY+ YAER FFPGH PL P + TV QGL QLS
Sbjct: 1338 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1397
Query: 1608 NLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQY 1667
NLLNSKLFL IHTLE Q +FS RDR +VASLL++ALHGKLEY TDI+RTLL DL A Y
Sbjct: 1398 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1457
Query: 1668 VAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVT 1727
V +NPKLMLRRTET+VEKLLTNW+SICLY F+R+ GEPLYMLFR I++QVDKGPVD+VT
Sbjct: 1458 VHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVT 1517
Query: 1728 GKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQG------VPVKVLDCDTISQAK 1781
GKAK TLND+RLLREDVE++PLTL L VGPGAG A G VP +VLD DTI+Q K
Sbjct: 1518 GKAKRTLNDSRLLREDVEFQPLTLMVL--VGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1575
Query: 1782 EKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKV 1841
EK+LDQ+YKG P +QRP LD+EWRSG+AGHL LSDED+TS Q W+RLNTLQHYKV
Sbjct: 1576 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1635
Query: 1842 PDGATVALVPCLTKH--VLRENQDYVP-GERTPMLEDVDEGGIRPWHLVKPSDEPEPPRP 1898
PDGATV LVP L + + + P GE P LED +EGG+ WHLVK ++EPE +
Sbjct: 1636 PDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKV 1695
Query: 1899 RRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLL 1958
R SLR E RAKAIPEIYLTRLLSMKGTLQKFVDD FQ ILS +RP+P+AVKY FDLL
Sbjct: 1696 RCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLL 1755
Query: 1959 DEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMD 2018
DE A++HGI D T+HIWKTNSL LRFW+N +KNPQ +FDV+ SDN+DA+L VIAQTF+D
Sbjct: 1756 DELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFID 1815
Query: 2019 ACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNY 2078
+CT ++HK+GRDSP+NKLLYAR+IPRYK+MVERYYADIRQ+ PAS QEMNS LAELS NY
Sbjct: 1816 SCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNY 1875
Query: 2079 SGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
+ AL ELY +I++YYDQII+ALEED QK+QL RLQQ+AA VENKVTDL
Sbjct: 1876 TSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1932
Score = 560 bits (1442), Expect = e-159
Identities = 326/717 (45%), Positives = 417/717 (58%), Gaps = 51/717 (7%)
Query: 2 PALGPALLQALWAGWVLTLQPLPPTA---FTPNGTYLQHLARDPTSGTLYLGATNFLFQL 58
P G LL L L+ PLP T F+ T L HLA P GTLY+GA N LFQL
Sbjct: 46 PPFGLCLLLLL-----LSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQL 100
Query: 59 SPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
SP LQLEA TGPV+DS DC+P P ECPQAQ T+N NQLLLVS A LV CG V Q
Sbjct: 101 SPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQ 160
Query: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
GVCE RRLG + ++L + E PGD Q+VAAN P V+TVGLV L G LL V RG +
Sbjct: 161 GVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVP-LPGRDLLLVARGLAGK- 218
Query: 177 VGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRD 236
+ G+PP+ R L P FS E +L VG S+Y++ +V AFA SAYF+F RR
Sbjct: 219 LSAGVPPLAIRQLAGSQP---FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRG 275
Query: 237 LQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAA 296
+AQ+ +R+YV+RVCL D + YSYVE+PLAC+G GLIQAA +A L
Sbjct: 276 ARAQAE-YRSYVARVCLGDTNLYSYVEVPLACQG--QGLIQAAFLAPG-------TLLGV 325
Query: 297 FSSAAPPTVGRPPSAAAGASGA-SALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
F AAG G +ALCAFP+ E+ + R CYT GR G E A
Sbjct: 326 F--------------AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEAT 371
Query: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
+EY V S C LP+D+ ++YPCG +HTPSP+A R PLE P+L+ G ++AVA DG
Sbjct: 372 VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKL-GQPVSAVAALQADG 430
Query: 416 HTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTL 474
H IAFLGD+QGQL++V+L GS G Y +Q + GSA+S DL D + HLYV+T +
Sbjct: 431 HMIAFLGDTQGQLYKVFLH-GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQV 489
Query: 475 LKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCL 534
++PVA+C Q DCASCL +DP CGWCVL GRC+R+ +C R QWLWS++ + CL
Sbjct: 490 DRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCL 549
Query: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
+ ++ P + R+E +V LSVP LP L E + C FG++ S A + G V C +P
Sbjct: 550 HIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQD 609
Query: 595 EAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWC 654
+ P+ P G D+V+V + L F V +A T+ SFYDC AV L +A C+ACV S W C+WC
Sbjct: 610 QVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWC 669
Query: 655 VWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPV 711
C + C G + D RG P P+ P +PV
Sbjct: 670 PQSSHCVYGEHCPEGERTIYSAQEV---DIQVRG-----PGACPQVEGLAGPHLVPV 718
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 1264 bits (3272), Expect = 0.0
Identities = 690/1257 (54%), Positives = 842/1257 (66%), Gaps = 40/1257 (3%)
Query: 902 ELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEV 961
E++ G +CP VE + G L+PV E + L RNL F+ P C +EL G
Sbjct: 670 EVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELR 729
Query: 962 VVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYD 1021
+ A +E E D+ + CQ HQ Q EL V +++ + R+D+ L+V+LYD
Sbjct: 730 GLPATLE-ETAGDSGL-IHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYD 787
Query: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGP 1081
C++GH DCS CQ A GC+WC +P C C AV CPAP I +VEPLTGP
Sbjct: 788 CAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPG-AVELLCPAPSIDAVEPLTGP 846
Query: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
+GG +TI GSNLG+ DV V+VA PC + Y S+ +VC+T + G
Sbjct: 847 PEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPV 906
Query: 1142 AVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD 1201
V + + G+S F YQDP + S+ P GP+AGGT+LT+ G L TG + VG
Sbjct: 907 RVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGG--NTSAFVGG 964
Query: 1202 QPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTK 1261
QPC +L E + C T P+ P V V FG +R L F+YT +P + +A P+
Sbjct: 965 QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSA 1024
Query: 1262 SFLSGGREICVRGQNLDVVQTPRIRV------TVVSRMLQPSQGLGRRR----RVVPETA 1311
SF GGR I VRG LDVVQ P + V V + QP RR P+
Sbjct: 1025 SFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQAC 1084
Query: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTP 1371
LG Q C VNSS L+ CR+PA+P RV F LDN+ DFA+ +
Sbjct: 1085 IQLGGGLL--QCSTVCSVNSSSLLLCRSPAVPDRAHPQ--RVFFTLDNVQVDFASASGGQ 1140
Query: 1372 -FSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTL 1430
F Y+ +P L PL+ E P P+R KPG V VEGE L+L +SKEEV IG G C+VKTL
Sbjct: 1141 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1200
Query: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESP-GAFPVAA 1489
TR HLYCEPP P P + + LP+F VQMGN++ +LG VQY+ E P AFPV A
Sbjct: 1201 TRTHLYCEPPAHAPQPANGS------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1254
Query: 1490 QVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMT 1549
Q G+G+G ++L V+++ LMYR KSKQALRDY+KV +QLE+LE+ V D+C+KEFTDLMT
Sbjct: 1255 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1314
Query: 1550 EMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVP--ESRRPTVEQGLGQLS 1607
EMTDL+SDL GSGIPFLDY+ YAER FFPGH PL P + TV QGL QLS
Sbjct: 1315 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1374
Query: 1608 NLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQY 1667
NLLNSKLFL IHTLE Q +FS RDR +VASLL++ALHGKLEY TDI+RTLL DL A Y
Sbjct: 1375 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1434
Query: 1668 VAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVT 1727
V +NPKLMLRRTET+VEKLLTNW+SICLY F+R+ GEPLYMLFR I++QVDKGPVD+VT
Sbjct: 1435 VHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVT 1494
Query: 1728 GKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQG------VPVKVLDCDTISQAK 1781
GKAK TLND+RLLREDVE++PLTL L VGPGAG A G VP +VLD DTI+Q K
Sbjct: 1495 GKAKRTLNDSRLLREDVEFQPLTLMVL--VGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1552
Query: 1782 EKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKV 1841
EK+LDQ+YKG P +QRP LD+EWRSG+AGHL LSDED+TS Q W+RLNTLQHYKV
Sbjct: 1553 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1612
Query: 1842 PDGATVALVPCLTKH--VLRENQDYVP-GERTPMLEDVDEGGIRPWHLVKPSDEPEPPRP 1898
PDGATV LVP L + + + P GE P LED +EGG+ WHLVK ++EPE +
Sbjct: 1613 PDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKV 1672
Query: 1899 RRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLL 1958
R SLR E RAKAIPEIYLTRLLSMKGTLQKFVDD FQ ILS +RP+P+AVKY FDLL
Sbjct: 1673 RCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLL 1732
Query: 1959 DEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMD 2018
DE A++HGI D T+HIWKTNSL LRFW+N +KNPQ +FDV+ SDN+DA+L VIAQTF+D
Sbjct: 1733 DELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFID 1792
Query: 2019 ACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNY 2078
+CT ++HK+GRDSP+NKLLYAR+IPRYK+MVERYYADIRQ+ PAS QEMNS LAELS NY
Sbjct: 1793 SCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNY 1852
Query: 2079 SGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
+ AL ELY +I++YYDQII+ALEED QK+QL RLQQ+AA VENKVTDL
Sbjct: 1853 TSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909
Score = 560 bits (1442), Expect = e-159
Identities = 326/717 (45%), Positives = 417/717 (58%), Gaps = 51/717 (7%)
Query: 2 PALGPALLQALWAGWVLTLQPLPPTA---FTPNGTYLQHLARDPTSGTLYLGATNFLFQL 58
P G LL L L+ PLP T F+ T L HLA P GTLY+GA N LFQL
Sbjct: 23 PPFGLCLLLLL-----LSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQL 77
Query: 59 SPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
SP LQLEA TGPV+DS DC+P P ECPQAQ T+N NQLLLVS A LV CG V Q
Sbjct: 78 SPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQ 137
Query: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
GVCE RRLG + ++L + E PGD Q+VAAN P V+TVGLV L G LL V RG +
Sbjct: 138 GVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVP-LPGRDLLLVARGLAGK- 195
Query: 177 VGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRD 236
+ G+PP+ R L P FS E +L VG S+Y++ +V AFA SAYF+F RR
Sbjct: 196 LSAGVPPLAIRQLAGSQP---FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRG 252
Query: 237 LQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAA 296
+AQ+ +R+YV+RVCL D + YSYVE+PLAC+G GLIQAA +A L
Sbjct: 253 ARAQAE-YRSYVARVCLGDTNLYSYVEVPLACQG--QGLIQAAFLAPG-------TLLGV 302
Query: 297 FSSAAPPTVGRPPSAAAGASGA-SALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
F AAG G +ALCAFP+ E+ + R CYT GR G E A
Sbjct: 303 F--------------AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEAT 348
Query: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
+EY V S C LP+D+ ++YPCG +HTPSP+A R PLE P+L+ G ++AVA DG
Sbjct: 349 VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKL-GQPVSAVAALQADG 407
Query: 416 HTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTL 474
H IAFLGD+QGQL++V+L GS G Y +Q + GSA+S DL D + HLYV+T +
Sbjct: 408 HMIAFLGDTQGQLYKVFLH-GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQV 466
Query: 475 LKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCL 534
++PVA+C Q DCASCL +DP CGWCVL GRC+R+ +C R QWLWS++ + CL
Sbjct: 467 DRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCL 526
Query: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
+ ++ P + R+E +V LSVP LP L E + C FG++ S A + G V C +P
Sbjct: 527 HIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQD 586
Query: 595 EAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWC 654
+ P+ P G D+V+V + L F V +A T+ SFYDC AV L +A C+ACV S W C+WC
Sbjct: 587 QVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWC 646
Query: 655 VWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPV 711
C + C G + D RG P P+ P +PV
Sbjct: 647 PQSSHCVYGEHCPEGERTIYSAQEV---DIQVRG-----PGACPQVEGLAGPHLVPV 695
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 988 bits (2553), Expect = 0.0
Identities = 555/1161 (47%), Positives = 740/1161 (63%), Gaps = 59/1161 (5%)
Query: 985 QLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQYGCVWC 1044
+LS++A + L + L+++ G+ +DS LHV LY+CS G DCS C+ A P Y C WC
Sbjct: 727 KLSHDANET-LPLHLYVKSYGK-NIDSK--LHVTLYNCSFGRSDCSLCRAANPDYRCAWC 782
Query: 1045 EGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLG 1104
G+ RCV C ++CP P+I ++P TGP+ GG R+TI GSNLG D+
Sbjct: 783 GGQS-RCVYEALCN----TTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQ- 836
Query: 1105 MVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGR-GRGVSEHDFAYQDPK 1163
++VAG C+ + Y VS+ +VC+ A+ G V+V G+ GR F +Q PK
Sbjct: 837 RISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPK 896
Query: 1164 VHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRP 1223
S+ P +GP+AGGT LT++G+ L TG ED+RV + PC + + QL+C T P+
Sbjct: 897 PLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVT--KFGAQLQCVTGPQA 954
Query: 1224 TPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTP 1283
T + + V +G + F Y +P + + P +SF SGGR I V GQ ++Q
Sbjct: 955 TRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQ-- 1012
Query: 1284 RIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEPCHVNSSQLITCRTPALP 1343
R + V++ LQ Q + P T + N ++++ +PA+P
Sbjct: 1013 RFAMVVIAEPLQSWQPPREAESLQPMTVVGT----------DYVFHNDTKVVFL-SPAVP 1061
Query: 1344 GLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVE 1403
PE + V +D T F Y DPT E+ T + + +
Sbjct: 1062 EEPEAYNLTVLIEMDGHRALLRT-EAGAFEYVPDPTF-----ENFTGGVKKQVNKLIHAR 1115
Query: 1404 GENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTV 1463
G NL+ AM+ +E A +G C +KTLT LYCEPP QP P+ R+ +LPEF V
Sbjct: 1116 GTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIV 1175
Query: 1464 QMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLM----YRRKSKQAL 1519
+ G+ + LG V+YD + V L + L+ + +++++ + Y RKS+QA
Sbjct: 1176 KFGSREWVLGRVEYDTR-------VSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAE 1228
Query: 1520 RDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFF-- 1577
R+Y+K++ QLE LE SVRDRCKKEFTDLM EM D T+D+ +GIP LDYK Y +R+FF
Sbjct: 1229 REYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLP 1288
Query: 1578 --PGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRA 1635
G ++ + L +PE RRP VEQ L Q SNLLNSK FL FIHTLE+QR FSAR +
Sbjct: 1289 SKDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKV 1348
Query: 1636 YVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKNPKLMLRRTETVVEKLLTNWMSIC 1694
Y ASLLTVALHGKLEY+TDI+ TL +L+ QYV AKNPKLMLRR+ETVVE++L+NWMSIC
Sbjct: 1349 YFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERMLSNWMSIC 1408
Query: 1695 LYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNAL 1754
LY +++DS GEPLY LF+ IKHQV+KGPVD+V KAKYTLND LL +DVEY PLT++ +
Sbjct: 1409 LYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVI 1468
Query: 1755 LAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGH 1814
+ +PVKVL+CDTISQ KEK++DQ+Y+G P + P P ++ +EWR G
Sbjct: 1469 VQ----DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQ 1524
Query: 1815 LILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLE 1874
ILSD D+TS+ +G W+R+NTL HY V DGAT+ L ++Q +PGER +LE
Sbjct: 1525 -ILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKVGVSQQPEDSQQDLPGERHALLE 1583
Query: 1875 DVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVD 1934
+ + R WHLV+P+DE + + +RGS++ E+ER KAI EIYLTRLLS+KGTLQ+FVD
Sbjct: 1584 EEN----RVWHLVRPTDEVDEGKSKRGSVK--EKERTKAITEIYLTRLLSVKGTLQQFVD 1637
Query: 1935 DLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQ 1994
+ FQ +L+ VP AVKYFFD LDEQA++H I D+DTIHIWKTNSLPLRFW+NI+KNP
Sbjct: 1638 NFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVNILKNPH 1697
Query: 1995 FVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYA 2054
F+FDV + +DA L VIAQTFMDACT +HKL RDSP NKLLYA++I YK+MVE YY
Sbjct: 1698 FIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVEDYYK 1757
Query: 2055 DIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQK 2114
IRQ V SDQ+MN+ LAE+S ++ L VALH+LY+Y KYYD+II ALEED AQK
Sbjct: 1758 GIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDPAAQK 1817
Query: 2115 MQLGYRLQQIAAAVENKVTDL 2135
MQL +RLQQIAAA+ENKVTDL
Sbjct: 1818 MQLAFRLQQIAAALENKVTDL 1838
Score = 417 bits (1072), Expect = e-116
Identities = 251/670 (37%), Positives = 350/670 (52%), Gaps = 41/670 (6%)
Query: 35 LQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPT 94
L HLA D SG +YLGA N L+QL LQLE V+TGP LD++ C PP+ +C +A+ T
Sbjct: 34 LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMT 93
Query: 95 NNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVST 152
+N NQLLL+ P LV CGS+ +G+C R L + L + G+ +VA+ND V+T
Sbjct: 94 DNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVAT 153
Query: 153 VGLVAQ-GLAGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQAAF-SYEETAKLAVGR 210
VGLV+ G G+ +LFVG+G G ++TR L D + AF +Y + A G
Sbjct: 154 VGLVSSTGPGGDRVLFVGKGNGPHDNG---IIVSTRLLDRTDSREAFEAYTDHATYKAGY 210
Query: 211 LSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACE- 269
LS + FV+AF G +F+F ++D R ++R+C D +YYSY+E+ L C
Sbjct: 211 LSTNTQQFVAAFEDGPYVFFVFNQQDKHPARN--RTLLARMCREDPNYYSYLEMDLQCRD 268
Query: 270 ----GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFP 325
+G AA+VA G VL+A FS S ++G GA LC FP
Sbjct: 269 PDIHAAAFGTCLAASVAAP---GSGRVLYAVFSR---------DSRSSGGPGAG-LCLFP 315
Query: 326 LDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSP 385
LD+V R+ACYT A D + Y + + C + ++PCGS+H P P
Sbjct: 316 LDKVHAKMEANRNACYTGTREARD---IFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYP 372
Query: 386 MASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQ 445
+ SR L T +L+ G+ LTAV V E+ HT+AFLG S G++ +VYL P Y +
Sbjct: 373 LGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSI 432
Query: 446 SIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLL 505
++ V RDL G LY MTQ + ++PV C + C C +DPYCGWCV+
Sbjct: 433 LVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVE 492
Query: 506 GRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPG 565
GRC+R++EC R + WLWS C+ V + P N+SR EV L+V LP L
Sbjct: 493 GRCTRKAECPRAEEASHWLWS--RSKSCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEE 550
Query: 566 ESYSCHFGEH-QSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVE--LRFGAVVIAKT 622
+ C FGE PA + G V+C S PS PV P G D+V+V+++ LR G + +
Sbjct: 551 DELLCLFGESPPHPARVEGEAVICNS--PSSIPVTPPGQDHVAVTIQLLLRRGNIFLTSY 608
Query: 623 SLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSP 682
FYDC L + C +CVS+RW C W + H C + +V +H +
Sbjct: 609 QYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRAH----MED 664
Query: 683 DPPARGGPSP 692
P GPSP
Sbjct: 665 SCPQFLGPSP 674
Score = 34.7 bits (78), Expect = 1.0
Identities = 48/215 (22%), Positives = 75/215 (34%), Gaps = 33/215 (15%)
Query: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
S ++L C SC+++R C W + C S PE + E C Q S
Sbjct: 620 SLEENLPCISCVSNRWT-CQWDLRYHECREASP-----NPEDGIVRAHMEDSCPQFLGPS 673
Query: 541 PANISREETREVFLSVPDLPPLWPGESYSCHFG----EHQSPALLTGSGVMC---PSPDP 593
P I +V +L + + S H G + P + SG P
Sbjct: 674 PLVIPMNHETDVNFQGKNLDTV---KGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSH 730
Query: 594 SEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSR--WGC 651
LP YV +G + +K ++ Y+C + C C ++ + C
Sbjct: 731 DANETLPLHL-YVK-----SYGKNIDSKLHVTLYNCSF-----GRSDCSLCRAANPDYRC 779
Query: 652 NWCVWQHLCTHKASC----DAGPMVASHQSPLVSP 682
WC Q C ++A C + P V + P P
Sbjct: 780 AWCGGQSRCVYEALCNTTSECPPPVITRIQPETGP 814
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 813 bits (2100), Expect = 0.0
Identities = 501/1248 (40%), Positives = 685/1248 (54%), Gaps = 124/1248 (9%)
Query: 925 MPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPPPDTQCHVTCQQH 984
+PV V + I L RNL Q G EC+ + G V A + CQ
Sbjct: 694 VPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTAL------RFNSSSLQCQNS 747
Query: 985 QLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQYGCVW 1043
SYE +L V L + G +D+ + + LY C C C A P++ C W
Sbjct: 748 SYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGW 807
Query: 1044 CEGERPRCVTREACG--------EAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNL 1095
C ER RC R C A +++C P I + P TGP GGTR+TI G NL
Sbjct: 808 CVAER-RCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENL 866
Query: 1096 GQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRG-----R 1150
G +DV V V V C+ EY + +VC G + A VEV R R
Sbjct: 867 GLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYR 926
Query: 1151 GVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQ 1210
+S F + P + + P+RGP +GGT + + GS L G D+ V VG +PC +
Sbjct: 927 ALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAG--SDVAVSVGGRPCSF-SWR 983
Query: 1211 QSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREI 1270
S ++RC T P +P + P+ + + ++ YT DP I P S SGG +
Sbjct: 984 NSREIRCLTPPGQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLL 1043
Query: 1271 CVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEPCHVN 1330
V G NL V+ PRIR G+ R E C V
Sbjct: 1044 TVTGTNLATVREPRIRAKY--------GGIER---------------------ENGCLVY 1074
Query: 1331 SSQLITCRTPAL-------PGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPL 1383
+ + CR P++ P L E P + F++DN V LN T F Y DP L+PL
Sbjct: 1075 NDTTMVCRAPSVANPVRSPPELGERP-DELGFVMDN-VRSLLVLNSTSFLYYPDPVLEPL 1132
Query: 1384 NPEDPTMPFRHKPGSVFSVEGENL---DLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
+P T KP S ++G NL S+ +IG PC + T++ L CE P
Sbjct: 1133 SP---TGLLELKPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAP 1188
Query: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
L H + TV+ G FS G +Q +S P A VG+G G LL
Sbjct: 1189 ---NLTGQHKV----------TVRAGGFEFSPGTLQVYSDSLLTLP--AIVGIGGGGGLL 1233
Query: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
L ++ +++ Y+RKS+ A R K++Q+Q++NLES V CK+ F +L T++ +LT+DL G
Sbjct: 1234 LLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDG 1293
Query: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
+GIPFLDY+ YA R+ FPG + P+ +++ V + VE+ L LL K FL FI
Sbjct: 1294 AGIPFLDYRTYAMRVLFPGIEDHPVLKEMEV----QANVEKSLTLFGQLLTKKHFLLTFI 1349
Query: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKN-PKLMLRR 1678
TLE+QR+FS RDR VASL+ AL G++EY T +L+ LLSDL+ + + +KN PKL+LRR
Sbjct: 1350 RTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRR 1409
Query: 1679 TETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNR 1738
TE+V EK+LTNW + LY F+++ GEPL+ML+ IK Q++KGP+D++TG+A+Y+L++++
Sbjct: 1410 TESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDK 1469
Query: 1739 LLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRP 1798
L+R+ ++Y+ LTLN V P A VPVK LDCDT++QAKEK+LD YKGVP +QRP
Sbjct: 1470 LIRQQIDYKTLTLNC---VNPENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRP 1526
Query: 1799 DPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVL 1858
+D+EWR G +IL DEDVT+++ W+RLNTL HY+V DG++VALVP T
Sbjct: 1527 KAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYN 1586
Query: 1859 RENQDYVPGE-------------------RTPMLEDVDEGGIRPWHLVKPSDEPEPPRPR 1899
N RTPM+ E G + WHLVK D +
Sbjct: 1587 ISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDHLDQREGD 1646
Query: 1900 RGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR---PVPLAVKYFFD 1956
RGS K + EIYLTRLL+ KGTLQKFVDDLF+ I ST+ +PLA+KY FD
Sbjct: 1647 RGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFD 1697
Query: 1957 LLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTF 2016
LDEQA +H I D D H WK+N LPLRFW+N+IKNPQFVFD+ + DA L V+AQTF
Sbjct: 1698 FLDEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTF 1757
Query: 2017 MDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSW 2076
MD+C+ ++HKLG+DSP NKLLYA+DIP YK VERYYADI + SDQ+M++ LAE S
Sbjct: 1758 MDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSR 1817
Query: 2077 NYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQI 2124
+ + ALHE+Y YI KY D+I+ ALE+D A++ +L +L+Q+
Sbjct: 1818 LHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQV 1865
Score = 256 bits (653), Expect = 2e-67
Identities = 218/751 (29%), Positives = 332/751 (44%), Gaps = 86/751 (11%)
Query: 24 PPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPV 83
P F+ + L HL +G +Y+GA N +++LS L L TGPV D+ C PP
Sbjct: 17 PFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPP 76
Query: 84 MPDECPQAQ-PTNNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDT 140
CP T+N N+LLL+ A L+ CGS QG+C+ RL L +L R
Sbjct: 77 SVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRK--E 134
Query: 141 QYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQA---A 197
Y+++ A S G++ G G+ + G G P +++R L + A
Sbjct: 135 HYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFG 194
Query: 198 FSYEET-----AKLAVGRLSEYSH---HFVSAFARGASAYFLFLRRDLQAQS------RA 243
F Y++ K+ LS++ ++V +F Y+L L+ D Q S
Sbjct: 195 FVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHF 254
Query: 244 FRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQAAAVAT-SREVAHG-------EVL 293
F + + R+C+ D +YSYVE P+ CE G Y L+Q A ++ R +AH +VL
Sbjct: 255 FTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVL 314
Query: 294 FAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEV 353
F F+ V +PP SALC F L + +CY EG+
Sbjct: 315 FTVFAQGQKNRV-KPPKE-------SALCLFTLRAIKEKIKERIQSCYRGEGKLS----- 361
Query: 354 AYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVT 411
+ + +N + C P+ D + CG D P+ V +E TP+ LTAVA
Sbjct: 362 --LPWLLNKELGCINSPLQIDDDF-CGQDFN-QPLGGTVTIEGTPLFVDKDDGLTAVAAY 417
Query: 412 MEDGHTIAFLGDSQGQLHRVYL---GPGSDGHP---YSTQSIQQGSAVSRDLTFDGTFEH 465
G T+ F G G++ ++ + PG G P Y + Q+GS + RDL ++
Sbjct: 418 DYRGRTVVFAGTRSGRIRKILVDLSNPG--GRPALAYESVVAQEGSPILRDLVLSPNHQY 475
Query: 466 LYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLW 525
LY MT+ + +VPV SC Q+ C CL RDP+CGWCVL CSRR C R P+++
Sbjct: 476 LYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAA 535
Query: 526 SFQPELGCLQVAAMSPANISREETR-EVFLSVPDLPPLWPGESYSCHFGEH-QSPALLTG 583
L C+Q+ + P N+S ++ + L ++P L G +C F + +S ++L
Sbjct: 536 DL---LQCVQL-TVQPRNVSVTMSQVPLVLQAWNVPDLSAG--VNCSFEDFTESESVLED 589
Query: 584 SGVMCPSPDPSEAPVLPRGAD---YVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQ 640
+ C SP E + RG V + ++ + A FY+C
Sbjct: 590 GRIHCRSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSV------HQS 643
Query: 641 CQACVSSRWGCNWCVWQHLCTHK-ASCD--AGPMVASHQSPLVSPDPPARGGPSPSPPTA 697
C +CV+ + C+WC ++H+CTH A C G + S P + P P
Sbjct: 644 CLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVVKPIT 703
Query: 698 PKALATPAP-------DTLPVEPGAPSTATA 721
A P P + L PG+P+ TA
Sbjct: 704 LAARNLPQPQSGQRGYECLFHIPGSPARVTA 734
Score = 46.6 bits (109), Expect = 3e-04
Identities = 63/255 (24%), Positives = 94/255 (36%), Gaps = 36/255 (14%)
Query: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRR-SECSRGQGPEQWLWSFQPELGCLQVAAM 539
+C+ H C SC+ P C WC C+ ++C+ +G C Q+
Sbjct: 637 NCSVHQSCLSCVNGSFP-CHWCKYRHVCTHNVADCAFLEG------RVNVSEDCPQILPS 689
Query: 540 SPANISREETREVFLSVPDLPPLWPGE-SYSCHFGEHQSPALLTGSGVMCPSPDPSEAPV 598
+ + + + L+ +LP G+ Y C F SPA +T S +
Sbjct: 690 TQIYVPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTALRFNSSSLQCQNSSY 749
Query: 599 LPRGADYVSVSVELRF---GAVVI---AKTSLSFYDCVAVTELRPSAQCQACVSS--RWG 650
G D + V L G VI Y C A+ E C C+ + R+
Sbjct: 750 SYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRE-----SCGLCLKADPRFE 804
Query: 651 CNWCVWQHLCTHKASCDAG-PMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTL 709
C WCV + C+ + C A P H AR G S T PK L +P+T
Sbjct: 805 CGWCVAERRCSLRHHCAADTPASWMH----------ARHGSSRC--TDPKILKL-SPETG 851
Query: 710 PVEPGAPSTATASDI 724
P + G T T ++
Sbjct: 852 PRQGGTRLTITGENL 866
Score = 33.5 bits (75), Expect = 2.3
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 10/81 (12%)
Query: 471 QSTLLKVPVASCAQHLDCASCLAHRDPY--CGWCVLLGRCSRRSECSRGQGPEQWLWSFQ 528
Q+ L K P A C CL DP CGWCV RCS R C+ P W+ +
Sbjct: 780 QAHLYKCP----ALRESCGLCLK-ADPRFECGWCVAERRCSLRHHCA-ADTPASWMHARH 833
Query: 529 PELGCL--QVAAMSPANISRE 547
C ++ +SP R+
Sbjct: 834 GSSRCTDPKILKLSPETGPRQ 854
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 793 bits (2047), Expect = 0.0
Identities = 482/1259 (38%), Positives = 694/1259 (55%), Gaps = 120/1259 (9%)
Query: 913 CPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPP 972
CP + V L+PV V + I L +NL Q G EC++ ++G E V A
Sbjct: 701 CPQLLRVD-KILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPAL------ 753
Query: 973 PDTQCHVTCQQHQLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSR 1031
V CQ SYE ++ L V L + G +D+ V LY C C
Sbjct: 754 RFNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGL 813
Query: 1032 CQTAMPQYGCVWCEGERPRCVTREACGEAEA-------VATQCPAPLIHSVEPLTGPVDG 1084
C A P + C WC+G +C R+ C E+ ++C P I + P+TGP +G
Sbjct: 814 CLKADPDFACGWCQGPG-QCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREG 872
Query: 1085 GTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG-ASGEEVAGATAV 1143
GT+VTIRG NLG +D+ V VAGV C+ Y + +VC G A + AG +
Sbjct: 873 GTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEI 932
Query: 1144 EVP---GRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200
V S + + + + P+RGP +GGT++T+ G+ L G ++ V+ G
Sbjct: 933 CVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAG--SNVVVMFG 990
Query: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260
QPC L + + C T+ + V+V + Q F+Y DP I P
Sbjct: 991 KQPC-LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIH-QDLVFQYVEDPTIVRIEPE 1048
Query: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320
S +SG I V G +LD++Q P+IR
Sbjct: 1049 WSIVSGNTPIAVWGTHLDLIQNPQIRA-----------------------------KHGG 1079
Query: 1321 QQFEEPCHVNSSQLITCRTPAL---PGLPEDPWVRVE---FILDNLVFDFATLNPTPFSY 1374
++ C V ++ +TC+ PAL P D R E FILDN V LN T F+Y
Sbjct: 1080 KEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDN-VQSLLILNKTNFTY 1138
Query: 1375 EADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMS----KEEVVAMIGDGPCVVKTL 1430
+P + P KPG+ ++G+NL ++ K ++G+ PC V T+
Sbjct: 1139 YPNPVFEAFGPSGI---LELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPCTV-TV 1194
Query: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQ 1490
+ L CE P + RH + ++G + +S G V +SP + P A
Sbjct: 1195 SDVQLLCESP--NLIGRHKVM-----------ARVGGMEYSPGMVYIAPDSPLSLP--AI 1239
Query: 1491 VGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTE 1550
V + V LL + ++ +++ Y+RKS+++ K++Q+Q++NLES V CK+ F +L T+
Sbjct: 1240 VSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTD 1299
Query: 1551 MTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLL 1610
+ +LTSDL G+GIPFLDY+ Y R+ FPG + P+ RDL VP R+ VE+GL + L+
Sbjct: 1300 IHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLI 1359
Query: 1611 NSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-A 1669
N+K+FL FI TLESQR+FS RDR VASL+ L KLEY TD+L+ LL+DL+ + + +
Sbjct: 1360 NNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLES 1419
Query: 1670 KN-PKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTG 1728
KN PKL+LRRTE+V EK+LTNW + LY F+++ GEPL+ LF IK Q++KGP+D++TG
Sbjct: 1420 KNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITG 1479
Query: 1729 KAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQL 1788
+A+Y+L++++L+R+ ++Y+ L L+ V P + VPVK+L+CDTI+Q KEK+LD +
Sbjct: 1480 EARYSLSEDKLIRQQIDYKTLVLSC---VSPDNANSPEVPVKILNCDTITQVKEKILDAI 1536
Query: 1789 YKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVA 1848
+K VP + RP +D+EWR G +IL DED+T++++ W+RLNTL HY+VPDG+ VA
Sbjct: 1537 FKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVA 1596
Query: 1849 LVP--------------CLTKHVLRENQDYVPGE------RTPMLEDVDEGGIRPWHLVK 1888
LV T EN G RTPM+ E G++ WHLVK
Sbjct: 1597 LVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVK 1656
Query: 1889 PSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR--- 1945
+ + RGS K + EIYLTRLL+ KGTLQKFVDDLF+ I ST+
Sbjct: 1657 NHEHGDQKEGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGS 1707
Query: 1946 PVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNM 2005
+PLA+KY FD LDEQA +HGI D H WK+N LPLRFW+N+IKNPQFVFD+ +
Sbjct: 1708 ALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSIT 1767
Query: 2006 DAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQ 2065
DA L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK VERYY+DI + SDQ
Sbjct: 1768 DACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQ 1827
Query: 2066 EMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQI 2124
+MN+ LAE S + + AL E++ Y+ KY ++I+ L+ D K +L Y+L+Q+
Sbjct: 1828 DMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQV 1886
Score = 238 bits (607), Expect = 5e-62
Identities = 182/663 (27%), Positives = 310/663 (46%), Gaps = 69/663 (10%)
Query: 37 HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQA-QPTN 95
HL D +G +YLGA N +++LS L++ T TGP D+ C PP + C + TN
Sbjct: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
Query: 96 NPNQLLLVS--PGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153
N N++LL+ L+ CGS++QG+C+ RL L +L P + Y++ + + S
Sbjct: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLG-EPYHKKE-HYLSGVNESGSVF 170
Query: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALWP---PDPQAAFSYEETAKLAVGR 210
G++ + LF+ G P I++R L D A+ + + ++ +
Sbjct: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228
Query: 211 LS--------EYSHHFVSAFARGASAYFLFLRRDLQA------QSRAFRAYVSRVCLRDQ 256
+ ++ ++V F+ G YFL L+ ++ + + + + + + R+C D
Sbjct: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288
Query: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREVA--------HGEVLFAAFSSAAPPTVG 306
+ SYVE+P+ CE G Y L+QAA ++ + V ++LF FS +
Sbjct: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMK 348
Query: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365
+ SALC F L +++ +CY EG + +A+++ D+ A
Sbjct: 349 --------SLDESALCIFILKQINDRIKERLQSCYRGEGTLD----LAWLKVKDIPCSSA 396
Query: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425
L T+D CG D +P+ + P+ ++T+V + H++AF+G
Sbjct: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452
Query: 426 GQLHRVYL-GPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQ 484
G+L ++ + GP + Y T + V RD+ F E LY+M++ L +VPV SC Q
Sbjct: 453 GKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQ 512
Query: 485 HLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANI 544
+ C CL DP+CGWCVL C+R+ C R + P + F E+ + P NI
Sbjct: 513 YQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRR----FASEMKQCVRLTVHPNNI 568
Query: 545 SREETREVF-LSVPDLPPLWPGESYSCHFGE-HQSPALLTGSGVMCPSPDPSEAP-VLPR 601
S + + L ++P L G +C F + + L+ G+ + C SP E P ++
Sbjct: 569 SVSQYNVLLVLETYNVPELSAG--VNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITE 626
Query: 602 GADYVSVSVELRF--GAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHL 659
D+ V ++L+ + A TS FY+C C +CV S + C+WC ++H+
Sbjct: 627 NGDHHVVQLQLKSKETGMTFASTSFVFYNCSV------HNSCLSCVESPYRCHWCKYRHV 680
Query: 660 CTH 662
CTH
Sbjct: 681 CTH 683
Score = 43.5 bits (101), Expect = 0.002
Identities = 52/204 (25%), Positives = 78/204 (38%), Gaps = 34/204 (16%)
Query: 481 SCAQHLDCASCLAHRDPY-CGWCVLLGRCSRRSE-CSRGQGPEQWLWSFQPELGCLQVAA 538
+C+ H C SC+ PY C WC C+ + CS +G + PE C Q+
Sbjct: 655 NCSVHNSCLSCV--ESPYRCHWCKYRHVCTHDPKTCSFQEGRVKL-----PE-DCPQLLR 706
Query: 539 MSPANISREETREVFLSVPDLPPLWPGE-SYSCHFG----EHQSPAL-LTGSGVMCPSPD 592
+ + E + + L +LP G+ Y C E + PAL S V C +
Sbjct: 707 VDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQNTS 766
Query: 593 PSEAPVLPRGADYVSVSVEL------RFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVS 646
S G + ++ VEL F A+ + Y C A+ E C C+
Sbjct: 767 YSY-----EGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRE-----SCGLCLK 816
Query: 647 SR--WGCNWCVWQHLCTHKASCDA 668
+ + C WC CT + C A
Sbjct: 817 ADPDFACGWCQGPGQCTLRQHCPA 840
Score = 35.0 bits (79), Expect = 0.79
Identities = 45/178 (25%), Positives = 72/178 (40%), Gaps = 28/178 (15%)
Query: 476 KVPVASC-AQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGC 533
KV + C A C CL A D CGWC G+C+ R C + QWL + C
Sbjct: 798 KVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQE--SQWLELSGAKSKC 855
Query: 534 L--QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMC-PS 590
++ + P RE +V + GE+ F + S + +GV C P
Sbjct: 856 TNPRITEIIPVTGPREGGTKVTIR---------GENLGLEFRDIASHVKV--AGVECSPL 904
Query: 591 PD---PSEAPVLPRG-------ADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPS 638
D P+E V G A +V + V + + + L ++ + +++L+PS
Sbjct: 905 VDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPS 962
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 788 bits (2036), Expect = 0.0
Identities = 488/1272 (38%), Positives = 695/1272 (54%), Gaps = 132/1272 (10%)
Query: 910 ASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVEC 969
+ CP + + L+PV + I L RNL Q G ECV+ ++G V A
Sbjct: 698 SEDCPQLVPTE-EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPAL--- 753
Query: 970 EPPPDTQCHVTCQQHQLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGD 1028
V CQ Y+ + L V + G +D+ + L V LY C+
Sbjct: 754 ---RFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRES 810
Query: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAV-------ATQCPAPLIHSVEPLTGP 1081
C C A ++ C WC GER RC + C + +C P I + ++GP
Sbjct: 811 CGLCLKADRKFECGWCSGER-RCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGP 869
Query: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
+GGTRVTI G NLG ++ V VAGVPC EY ++ +VC G + G T
Sbjct: 870 PEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVC---EMGHALVGTT 926
Query: 1142 AV-------EVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLED 1194
+ E S + + +P V S+ P RGP +GGT +T+ G L G
Sbjct: 927 SGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAG--SS 984
Query: 1195 IRVVVGDQPCHLLPEQQSEQLRCETSPRPT---PATLPVAVWFGATERRLQRGQFKYTLD 1251
+ V +G+Q C SE + C + P P + V+V + LQ F+Y D
Sbjct: 985 VAVYLGNQTCEFYGRSMSE-IVCVSPPSSNGLGPVPVSVSVDRAHVDSNLQ---FEYIDD 1040
Query: 1252 PNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETA 1311
P + P S SG + + G NLDV+Q PRIRV
Sbjct: 1041 PRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKF---------------------- 1078
Query: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPAL-----PGLP--EDPWVRVEFILDNLVFDF 1364
+ ++ C V ++ +TC P+L PGL E P F+ +N V
Sbjct: 1079 -------NGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERP-DEFGFVFNN-VQSL 1129
Query: 1365 ATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMS---KEEVVAMIG 1421
N T F Y +PT + L+P T KPGS ++G+NL S K +IG
Sbjct: 1130 LIYNDTKFIYYPNPTFELLSP---TGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIG 1186
Query: 1422 DGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGES 1481
+ PC V T++ L CEPP L H + V +G + FS G V +S
Sbjct: 1187 ETPCAV-TVSETQLLCEPP---NLTGQHKVM----------VHVGGMVFSPGSVSVISDS 1232
Query: 1482 PGAFPVAAQVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCK 1541
P A V + G SLL + VII+++ Y+RKS++ K++Q+Q++NLES V CK
Sbjct: 1233 LLTLP--AIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECK 1290
Query: 1542 KEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQ 1601
+ F +L T++ +LTSDL SGIP+LDY+ YA R+ FPG + P+ R+L V + + VE+
Sbjct: 1291 EAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEK 1350
Query: 1602 GLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLS 1661
L + L+N+K+FL FI TLE QR+FS RDR VASL+ L G+LEY TD+L+ LLS
Sbjct: 1351 ALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLS 1410
Query: 1662 DLVAQYVAK--NPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVD 1719
DL+ + + +PKL+LRRTE+V EK+LTNW + L+ F+++ GEPL+ML+ IK Q++
Sbjct: 1411 DLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQME 1470
Query: 1720 KGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQ 1779
KGP+D++TG+A+Y+L++++L+R+ +EY+ L LN V P + +PVKVL+CDTI+Q
Sbjct: 1471 KGPIDAITGEARYSLSEDKLIRQQIEYKTLILNC---VNPDNENSPEIPVKVLNCDTITQ 1527
Query: 1780 AKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHY 1839
KEK+LD +YK VP +QRP +D+EWR G ++L DED+T++++G W+RLNTL HY
Sbjct: 1528 VKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHY 1587
Query: 1840 KVPDGATVALVPCLTKH-------------VLRENQDY-------VPGERTPMLEDVDEG 1879
+V D + VALVP T + R + + R PM+ E
Sbjct: 1588 QVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLES 1647
Query: 1880 GIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQV 1939
G++ WHLVK D + RGS K + EIYLTRLL+ KGTLQKFVDDLF+
Sbjct: 1648 GVKVWHLVKNHDHGDQKEGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFET 1698
Query: 1940 ILST---SRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFV 1996
+ ST +PLA+KY FD LDEQA +H I D D H WK+N LPLRFW+N+IKNPQFV
Sbjct: 1699 LFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFV 1758
Query: 1997 FDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADI 2056
FD+ DA L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK VERYYADI
Sbjct: 1759 FDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADI 1818
Query: 2057 RQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQ 2116
+ SDQ+MN+ LAE S ++ + AL+E+Y Y++KY +++I ALE+D A++ +
Sbjct: 1819 AKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQR 1878
Query: 2117 LGYRLQQIAAAV 2128
L Y+++Q+ A+
Sbjct: 1879 LAYKVEQLINAM 1890
Score = 275 bits (702), Expect = 5e-73
Identities = 218/745 (29%), Positives = 345/745 (46%), Gaps = 89/745 (11%)
Query: 16 WVLTLQPLPPTAFTPNGTYLQHLARDPT---------SGTLYLGATNFLFQLSPGLQLEA 66
WVL PP A P + RD T +G +Y+GA N +++L+ L ++
Sbjct: 25 WVLLA---PPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQV 81
Query: 67 TVSTGPVLDSRDCLPPVMPDECPQAQP-TNNPNQLLLV--SPGALVVCGSVHQGVCEQRR 123
TGP D++ C PP++ C + TNN N+LL++ S L+ CGS++QGVC+ R
Sbjct: 82 AHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLR 141
Query: 124 LGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPP 183
L L +L+ P + Y+++ + + G++ + + LF+G G P
Sbjct: 142 LDDLF-ILVEPSHKKE-HYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVD--GKQDYFPT 197
Query: 184 ITTRALWPPDPQ--AAFSYE-------ETAKLAVGRLSEYSHH---FVSAFARGASAYFL 231
+++R L P DP+ A YE K+ L+ SH ++ FA G YFL
Sbjct: 198 LSSRKL-PRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFL 256
Query: 232 FLRRDL-------QAQSRAFRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQAAAVA 282
++ + A + + + R+C D ++SYV LP C G Y L+QAA +A
Sbjct: 257 TVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLA 316
Query: 283 TSRE--------VAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLAN 334
+ + +VLFA FS PP SALCAFP+ ++
Sbjct: 317 KPGDSLAQAFNITSQDDVLFAIFSKGQKQ-YHHPPDD-------SALCAFPIRAINLQIK 368
Query: 335 RTRDACYTREGRAEDGTEVAYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMASRVPL 392
+CY EG E + + + D C + PV D + CG D P+ P+
Sbjct: 369 ERLQSCYQGEGNLE-------LNWLLGKDVQCTKAPVPIDDNF-CGLDIN-QPLGGSTPV 419
Query: 393 EATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYL-GPGSDGHPYSTQSI-QQG 450
E + ++T+VA + +G+++ F+G G+L ++ GP G Y S+ + G
Sbjct: 420 EGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDG 479
Query: 451 SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSR 510
S + RD+ F +LYVM++ + +VPV SC Q+ C CL+ DP+CGWC L CSR
Sbjct: 480 SPILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSR 539
Query: 511 RSECSRGQGPEQWLWSFQPELGCLQVAAMSPANIS-REETREVFLSVPDLPPLWPGESYS 569
R +C + P ++ S C+ + A+ P++IS E +R + L V D P L G +
Sbjct: 540 RDKCQQAWEPNRFAASISQ---CVSL-AVHPSSISVSEHSRLLSLVVSDAPDLSAG--IA 593
Query: 570 CHFGE-HQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAV--VIAKTSLSF 626
C FG + ++GS V+C SP P + PV+P D+ + ++LR + T F
Sbjct: 594 CAFGNLTEVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKF 653
Query: 627 YDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTH---KASCDAGPMVASHQSPLVSPD 683
Y+C A C +CV+S + C+WC +++LCTH S G + S P + P
Sbjct: 654 YNCSA------HQLCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPT 707
Query: 684 PPARGGPSPSPPTAPKALATPAPDT 708
P KA P P +
Sbjct: 708 EEILIPVGEVKPITLKARNLPQPQS 732
Score = 35.4 bits (80), Expect = 0.60
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 20/114 (17%)
Query: 425 QGQLHRVYLGPGSDGHPYSTQSIQ-QGSAVSRD--------LTFDGTFEHLYVMTQSTLL 475
QG +HRV +++ S+Q Q S+ D + F + +++ L
Sbjct: 744 QGAIHRV------PALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDL 797
Query: 476 KVPVASCA-QHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWL-WS 526
KV + CA Q C CL A R CGWC RC+ C+ P WL WS
Sbjct: 798 KVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSSP--WLDWS 849
Score = 35.0 bits (79), Expect = 0.79
Identities = 48/203 (23%), Positives = 72/203 (35%), Gaps = 36/203 (17%)
Query: 481 SCAQHLDCASCL--AHRDPYCGWCVLLGRCSRR-SECSRGQGPEQWLWSFQPELGCLQVA 537
+C+ H C SC+ A R C WC C+ + CS +G C Q+
Sbjct: 655 NCSAHQLCLSCVNSAFR---CHWCKYRNLCTHDPTTCSFQEG------RINISEDCPQLV 705
Query: 538 AMSPANISREETREVFLSVPDLPPLWPGE-SYSCHFGE----HQSPAL-LTGSGVMCPSP 591
I E + + L +LP G+ Y C H+ PAL S V C +
Sbjct: 706 PTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNS 765
Query: 592 DPSEAPVLPRGADYVSVSVELRF---GAVVIAKTS---LSFYDCVAVTELRPSAQCQACV 645
G D +++V+ G +I + Y C A E C C+
Sbjct: 766 SYQYD-----GMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRE-----SCGLCL 815
Query: 646 SS--RWGCNWCVWQHLCTHKASC 666
+ ++ C WC + CT C
Sbjct: 816 KADRKFECGWCSGERRCTLHQHC 838
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 759 bits (1961), Expect = 0.0
Identities = 473/1199 (39%), Positives = 676/1199 (56%), Gaps = 131/1199 (10%)
Query: 979 VTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQ 1038
V C Q L + L L+ +DS E + V++Y+C++G DCS+C
Sbjct: 806 VRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQC-LGRED 864
Query: 1039 YG--CVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLG 1096
G C+W +G R R G + +A CPAP I ++EPL+GP+DGGT +TIRG NLG
Sbjct: 865 LGHLCMWSDGCRLR-------GPLQPMAGTCPAPEIRAIEPLSGPLDGGTLLTIRGRNLG 917
Query: 1097 QHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRGRGVSEHD 1156
+ + DV V + GV C Y VS +VC+TG + ++G V G+ S
Sbjct: 918 RRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKEGK--SRDR 975
Query: 1157 FAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD-QPCHLLPEQQSEQL 1215
F+Y P VHS+ P GP+AGGTR+T++G+ L G +++V+V D PC L + +
Sbjct: 976 FSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVG--SELQVLVNDTDPCTELMRTDTS-I 1032
Query: 1216 RCETSPRPTPATLPVAVWFGATERR-LQRGQ--FKYTLDPNITSAGPTKSFLSGGREICV 1272
C PA +PV V F ERR G F Y +P IT+ P +S +SGGR I V
Sbjct: 1033 ACTMPEGALPAPVPVCVRF---ERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITV 1089
Query: 1273 RGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEP--CHVN 1330
G+ +VQ + V + R EP C V
Sbjct: 1090 AGERFHMVQNVSMAVHHIGR--------------------------------EPTLCKVL 1117
Query: 1331 SSQLITCRTPAL---PGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPL-NPE 1386
+S LITC +P P D ++ D + L+P + L L NP+
Sbjct: 1118 NSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQ 1177
Query: 1387 DPTMP----FRHKPGSVFS--VEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
T +H PG + + E L + E IG C ++ ++ ++C
Sbjct: 1178 FSTAKREKWIKHHPGEPLTLVIHKEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSV- 1236
Query: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
+ +L A LP T+Q+GN ++ +Q G A V + + + LL
Sbjct: 1237 -------NESLGAAVGQLP-ITIQVGNFNQTIATLQLGGSE-----TAIIVSIVICSVLL 1283
Query: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
L V+ + ++ KS++A R ++K +Q+E +ES +R+ +K F +L T+MTDLT +L
Sbjct: 1284 LLSVVAL-FVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNR 1342
Query: 1561 S-GIPFLDYKVYAERIFFP------------------------GHRESPLHRDLGVPESR 1595
S GIPFL+YK + R FFP PL + +PES
Sbjct: 1343 SQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESC 1402
Query: 1596 RPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDI 1655
RP +E+G+ S+LLN+K FL F+H LE Q+ F+ RDR +ASLLT+ALHGKLEY+T I
Sbjct: 1403 RPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSI 1462
Query: 1656 LRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIK 1715
++ LL DL+ AKNPKLMLRRTE+VVEK+LTNWMSIC+Y+ +R++VGEP ++L IK
Sbjct: 1463 MKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIK 1522
Query: 1716 HQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCD 1775
Q++KG +D++TGKA+YTLN+ LLRE++E +P LN G G + V+ +D D
Sbjct: 1523 QQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNVSFQ---GCG-MDSLSVRAMDTD 1578
Query: 1776 TISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNT 1835
T++Q KEK+L+ K VP +Q P +D+EW + IL D D TS V+ ++LNT
Sbjct: 1579 TLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNT 1638
Query: 1836 LQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDE-PE 1894
L HYK+P+GA++A+ L + +D G ++D+D + +HLV P+DE E
Sbjct: 1639 LAHYKIPEGASLAMS-------LIDKKDNTLGR----VKDLDTE--KYFHLVLPTDELAE 1685
Query: 1895 PPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVP-LAVKY 1953
P + R S R K +PEIYLTRLLS KGTLQKF+DDLF+ ILS P LAVKY
Sbjct: 1686 PKKSHRQS------HRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKY 1739
Query: 1954 FFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIA 2013
FFD L+EQA++ GISD DT+HIWKTNSLPLRFW+NI+KNPQFVFD+ +D++DA L VIA
Sbjct: 1740 FFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIA 1799
Query: 2014 QTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAE 2073
Q F+DAC+++D +LG+DSP NKLLYA++IP Y+++V+RYY I+ P S+QEMN+ LAE
Sbjct: 1800 QAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAE 1859
Query: 2074 LSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKV 2132
S Y + VA+ E+YKY +Y QI+ ALE + TA++ QL ++ +Q+ A +E+ +
Sbjct: 1860 ESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNI 1918
Score = 251 bits (642), Expect = 4e-66
Identities = 222/742 (29%), Positives = 325/742 (43%), Gaps = 107/742 (14%)
Query: 30 PNGTYLQHLARDPTSGTLYLGATNFLFQLS-PGLQLEATVSTGPVLDSRDCLPPVMPD-- 86
P+ T + A D +GT+YL A N L+QLS L LEA + GPV DS C P +P
Sbjct: 54 PSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQAS 113
Query: 87 -ECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLR------PERP 137
E P+ + T+N N++L + PG +VVCGS++QG C+ RR G + + +R P P
Sbjct: 114 CEHPR-RLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEP 172
Query: 138 ----GDTQYVAANDPAVSTVGLV---AQGLAGEPLLFVGRGYTSRGVG------------ 178
VAAN P STVGLV A G G LL VG YT G
Sbjct: 173 VTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLL-VGATYTGYGSSFFPRNRSLEDHR 231
Query: 179 -GGIPPITTRALWPPDPQAAF-------SYEETAKLAVGRLSEYSHHFVSAFAR------ 224
P I R+L A S + K+ G ++ FVSAF
Sbjct: 232 FENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPP 291
Query: 225 GASAY-FLFLRRDLQA---QSRAFRAYVSRVCL-------RDQHYYSYVELPLACEGGR- 272
GA +Y +L L + +A +S+A R+ ++R+CL + SY++L L C GG
Sbjct: 292 GAQSYAYLALNSEARAGDKESQA-RSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAG 350
Query: 273 ----YGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDE 328
Y + + A R LFA F RP + A + +ALCAF +
Sbjct: 351 RGDLYSRLVSVFPARER-------LFAVFE--------RPQGSPAARAAPAALCAFRFAD 395
Query: 329 VDRLANRTRDACYTREG--------RAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSD 380
V R AC+ GT A E +N QL + LD CG+
Sbjct: 396 VRAAIRAARTACFVEPAPDVVAVLDSVVQGTGPA-CERKLN---IQLQPEQLD---CGAA 448
Query: 381 HTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGH 440
H P++ PL+ATP+ PG LT+VAV + +T FLG G+L ++ L
Sbjct: 449 HLQHPLSILQPLKATPVFRAPG--LTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVV 506
Query: 441 PYSTQSIQQGSAVSRDLTFDGTFE-HLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYC 499
++ G V + FD +LY+MT + +V VA+C H C C+ D YC
Sbjct: 507 SRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYC 566
Query: 500 GWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDL 559
GWC L RC+ + +C+ W + + C + + R+E + L +
Sbjct: 567 GWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGS 626
Query: 560 PPLWPGESYSCHFGEH-QSPALLTGSG-----VMCPSPDPSEAPVLPRGADYVSVSVELR 613
P G +C +G + ++ A + G C + P P D+V+V + +R
Sbjct: 627 LPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVR 686
Query: 614 FGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC-THKASCDAGPMV 672
I K + + YDC ++ P C +C+S++W C WC QH C ++++ C+A P
Sbjct: 687 VNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNP 746
Query: 673 ASHQS---PLVSPDPPARGGPS 691
S Q L+SP P G S
Sbjct: 747 TSPQDCPRTLLSPLAPVPTGGS 768
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 751 bits (1940), Expect = 0.0
Identities = 475/1263 (37%), Positives = 690/1263 (54%), Gaps = 136/1263 (10%)
Query: 921 GSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPPPDTQCHVT 980
G L+PV V + + L +NL Q G + ECV+ ++G + V A V
Sbjct: 690 GDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPA------VRFNSSSVQ 743
Query: 981 CQQHQLSYEALQP-ELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQY 1039
CQ SYE + + + + G +D +LY C C C A P++
Sbjct: 744 CQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRF 803
Query: 1040 GCVWCEGERPRCVTREACGEAEA-------VATQCPAPLIHSVEPLTGPVDGGTRVTIRG 1092
C WC E RC R C + T+C P I + PL GP +GGTRVTI G
Sbjct: 804 NCGWCISEH-RCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVG 862
Query: 1093 SNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEV-----PG 1147
NLG ++V + VAGV C EY + +VC S VE+
Sbjct: 863 DNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSA 920
Query: 1148 RGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLL 1207
R SE +++ P + P+RGP +GGTRLT++GS L G + V V D C +
Sbjct: 921 DFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAG--SRVTVTVRDSECQFV 978
Query: 1208 PEQQSEQLRCETSPRPT--PATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLS 1265
+ ++ + C SP T P+ P+ + + YT DP +T PT S ++
Sbjct: 979 -RRDAKAIVC-ISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIIN 1036
Query: 1266 GGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEE 1325
G I V G +L VQ PR+R + R + T
Sbjct: 1037 GSTAITVSGTHLLTVQEPRVRA---------------KYRGIETT--------------N 1067
Query: 1326 PCHVNSSQLITCRTPAL-PGLPEDPWVRVE------FILDNLVFDFATLNPTPFSYEADP 1378
C V + + C+ P + G P+ P + E F+LD+ V +LN + F+Y DP
Sbjct: 1068 TCQVINDTAMLCKAPGIFLGRPQ-PRAQGEHPDEFGFLLDH-VQTARSLNRSSFTYYPDP 1125
Query: 1379 TLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAM---SKEEVVAMIGDGPCVVKTLTRHHL 1435
+ +PL P KPGS ++G+NL A S+ +IG PC + T++ L
Sbjct: 1126 SFEPLGPSGV---LDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSL-TVSDTQL 1181
Query: 1436 YCEPPVE---QPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVG 1492
C+ P + QP+ V +G L F LG + E A + A +G
Sbjct: 1182 LCDSPSQTGRQPV----------------MVLVGGLEFWLGTLHISAER--ALTLPAMMG 1223
Query: 1493 LGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMT 1552
L G LL L + +++ Y+RK++ A R K++Q+Q++NLES V CK+ F +L T++
Sbjct: 1224 LAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIN 1283
Query: 1553 DLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNS 1612
+LT+ + IPFLDY+ YA R+ FPG P+ ++L P P VE+ L LL+S
Sbjct: 1284 ELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP----PNVEKALRLFGQLLHS 1339
Query: 1613 KLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKN 1671
+ F+ FIHTLE+Q +FS RDR VASL VAL +L+Y T +L+ LL+DL+ + + +KN
Sbjct: 1340 RAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKN 1399
Query: 1672 -PKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKA 1730
PKL+LRRTE+V EK+LTNW + L+ F+++ GEPL++L+ IK Q++KGP+D++TG+A
Sbjct: 1400 HPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEA 1459
Query: 1731 KYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYK 1790
+Y+L++++L+R+ ++Y+ LTL+ + G+ + VPVKVL+CD+I+QAK+K+LD +YK
Sbjct: 1460 RYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQ---VPVKVLNCDSITQAKDKLLDTVYK 1516
Query: 1791 GVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALV 1850
G+P +QRP +D+EWR G +IL DEDVT++++ W+RLN+L HY+V DG+ VALV
Sbjct: 1517 GIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALV 1576
Query: 1851 P------------CLTKHVLR--------ENQDYVPGERTPMLEDVDEGGIRPWHLVKPS 1890
P T+ + R + D + R PM+ E G + WHLVK
Sbjct: 1577 PKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSL-RSRAPMITPDQETGTKLWHLVKNH 1635
Query: 1891 DEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR---PV 1947
D + RGS K + EIYLTRLL+ KGTLQKFVDDLF+ + ST+ +
Sbjct: 1636 DHADHREGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSAL 1686
Query: 1948 PLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDA 2007
PLA+KY FD LDEQA Q ISD D H WK+N LPLRFW+N+IKNPQFVFD+ + DA
Sbjct: 1687 PLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDA 1746
Query: 2008 VLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEM 2067
L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK VERYY DI + SDQ+M
Sbjct: 1747 CLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDM 1806
Query: 2068 NSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAA 2127
++ L E S ++ D AL+ELY Y+ KY +I+TAL+ D + +K +L +L+QI +
Sbjct: 1807 DAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISL 1866
Query: 2128 VEN 2130
V +
Sbjct: 1867 VSS 1869
Score = 249 bits (635), Expect = 3e-65
Identities = 209/723 (28%), Positives = 320/723 (44%), Gaps = 76/723 (10%)
Query: 1 MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
MP++ LL L G L +P AF T L HLA +G +++GA N +F+L+P
Sbjct: 1 MPSVCLLLLLFLAVGGALGNRPF--RAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAP 58
Query: 61 GL-QLEATVSTGPVLDSRDCLPPVMPDECP-QAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
L +L A V TGPV D+ C PP C + P +N N+LLL+ A LV CGS+ Q
Sbjct: 59 NLTELRAHV-TGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQ 117
Query: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
G+C+ RL L +L P + A +P S G++ + G LFVG G
Sbjct: 118 GICQFLRLDDLFKLG-EPHHRKEHYLSGAQEPD-SMAGVIVEQGQGPSKLFVGTAVD--G 173
Query: 177 VGGGIPPITTRALWPPDPQA---AFSYEET-----AKLAVGRLSEYSH---HFVSAFARG 225
P +++R L + A + Y++ K+ LS Y +++ F
Sbjct: 174 KSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSA 233
Query: 226 ASAYFLFLRRDLQ------AQSRAFRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQ 277
+ YFL L+ D Q A + F + + R+C D +YSYVE P+ C G Y L+Q
Sbjct: 234 SFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQ 293
Query: 278 AAAVATSREV--------AHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEV 329
+A +A + A +VLF FS P + LC F L +
Sbjct: 294 SAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ--------TILCLFTLSNI 345
Query: 330 DRLANRTRDACYTREGRAEDGTEVAYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMA 387
+ R +CY EG + + +N + C P+ ++ CG P+
Sbjct: 346 NAHIRRRIQSCYRGEGTLA-------LPWLLNKELPCINTPMQ-INGNFCGLVLN-QPLG 396
Query: 388 SRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI 447
+E P+L + +VA H++ F+G G L +V + D H Y T +
Sbjct: 397 GLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPV 456
Query: 448 QQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGR 507
GS + RDL F H+Y++++ + ++PV +C Q+ CA+CL DP+CGWCVL R
Sbjct: 457 VDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHR 516
Query: 508 CSRRSECSRGQGPEQWLWSFQPELG-CLQVAAMSPANIS-REETREVFLSVPDLPPLWPG 565
C R C P F EL C+QV + P N+S ++ +++ ++P L G
Sbjct: 517 CCREGACLGASAPH----GFAEELSKCVQV-RVRPNNVSVTSPGVQLTVTLHNVPDLSAG 571
Query: 566 ESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRG---ADYVSVSVELRFGAVVIAKT 622
S + LL ++CPSP E L RG V + + + V A
Sbjct: 572 VSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGA 631
Query: 623 SLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCT---HKASCDAGPMVASHQSPL 679
FY+C + C +CV S + C+WC ++H CT H+ S G + + P
Sbjct: 632 DFVFYNCSVL------QSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPE 685
Query: 680 VSP 682
+ P
Sbjct: 686 ILP 688
Score = 42.0 bits (97), Expect = 0.006
Identities = 74/293 (25%), Positives = 115/293 (39%), Gaps = 49/293 (16%)
Query: 401 PGIQLTAVAVTMED---GHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDL 457
PG+QLT + D G + AF ++ + V L G P + S+Q+ A++R
Sbjct: 554 PGVQLTVTLHNVPDLSAGVSCAF--EAAAENEAVLLPSGELLCP--SPSLQELRALTRGH 609
Query: 458 TFDGTFEHLYVMTQSTLLKVPVA-----SCAQHLDCASCLAHRDPYCGWCVLLGRC-SRR 511
T L ++++ T ++ A +C+ C SC+ P C WC C SR
Sbjct: 610 GATRTVR-LQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYP-CHWCKYRHTCTSRP 667
Query: 512 SECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPGE-SYSC 570
ECS +G PE GC ++ I + + L +LP G+ +Y C
Sbjct: 668 HECSFQEGRVH-----SPE-GCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYEC 721
Query: 571 ----HFGEHQSPAL-LTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLS 625
+ + PA+ S V C + S G ++ EL F V +
Sbjct: 722 VVRVQGRQQRVPAVRFNSSSVQCQNASYSY-----EGDEHGDT--ELDFSVVWDGDFPID 774
Query: 626 --------FYDCVAVTELRPSAQCQACVSS--RWGCNWCVWQHLCTHKASCDA 668
Y C A RPS C C+ + R+ C WC+ +H C + C A
Sbjct: 775 KPPSFRALLYKCWAQ---RPS--CGLCLKADPRFNCGWCISEHRCQLRTHCPA 822
>gi|5032223 plexin C1 [Homo sapiens]
Length = 1568
Score = 405 bits (1042), Expect = e-112
Identities = 297/891 (33%), Positives = 436/891 (48%), Gaps = 105/891 (11%)
Query: 1244 GQFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRR 1303
G Y P+ + P +++SGG+ I + G+N DV+ ++S L+ + +
Sbjct: 746 GSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVIDN-----LIISHELKGNINVSE- 799
Query: 1304 RRVVPETACS-LGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVF 1362
T C L PS S + V V+ + +
Sbjct: 800 --YCVATYCGFLAPSLKSSKVRTN------------------------VTVKLRVQDTYL 833
Query: 1363 DFATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGD 1422
D TL Y DP E ++ EN + +SK+++ +
Sbjct: 834 DCGTLQ-----YREDPRFTGYRVESEV-----DTELEVKIQKENDNFNISKKDIEITLFH 883
Query: 1423 GP-----CVVKTLTRHHLYCEPPVEQPLPRHHALREAP---DSLPEFTVQMGNLRFSLGH 1474
G C + +TR+ + L + ++ A +S + V++GNL +
Sbjct: 884 GENGQLNCSFENITRNQ-----DLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVE- 937
Query: 1475 VQYDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLES 1534
Q S F + V LL + + V + R KSK+ R K QLE LES
Sbjct: 938 -QESVPSTWYFLIVLPV-------LLVIVIFAAVGVTRHKSKELSR---KQSQQLELLES 986
Query: 1535 SVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFFP--GHRESPLHRDLGVP 1592
+R + F +L + D+ D G+ +PFLDYK +A R FFP G D+
Sbjct: 987 ELRKEIRDGFAELQMDKLDVV-DSFGT-VPFLDYKHFALRTFFPESGGFTHIFTEDMHNR 1044
Query: 1593 ESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYF 1652
++ + L L L+ +K FL IHTLE Q+ FS +DR AS LT+AL KL Y
Sbjct: 1045 DANDKN--ESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYL 1102
Query: 1653 TDILRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFR 1712
T IL L DL+ Q PKLMLRRTE+VVEKLLTNWMS+CL F+R++VGEP Y+L
Sbjct: 1103 TSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVT 1162
Query: 1713 GIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGP---GAGEAQGVPV 1769
+ +++KGPVD +T KA YTLN++ LL + E+ + LN + P A + + V
Sbjct: 1163 TLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISV 1222
Query: 1770 KVLDCDTISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGL 1829
VLDCDTI QAKEK+ + +E + G +L + + ++
Sbjct: 1223 NVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDG 1282
Query: 1830 WRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKP 1889
+LNT+ HY++ +G+T+ + + T +E D+ HL+ P
Sbjct: 1283 ITKLNTIGHYEISNGSTIKVFKKIANF-------------TSDVEYSDD----HCHLILP 1325
Query: 1890 SDEPEPPRPRRGSLRGGERERAK---AIPEIYLTRLLSMKGTLQKFVDDLFQVILS-TSR 1945
E G+R R K + E+YLT+LLS K + ++ LF+ I S +
Sbjct: 1326 DSEAFQDVQ-------GKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS 1378
Query: 1946 PVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNM 2005
P A+KYFFD LD QA+ I+D D +HIWKTNSLPLRFW+NI+KNPQFVFD++ + ++
Sbjct: 1379 RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHI 1438
Query: 2006 DAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQ 2065
D L VIAQ FMDA +L + +LG+++P NKLLYA+DIP YK V+ YY IR P S
Sbjct: 1439 DGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSS 1498
Query: 2066 EMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQ 2116
EM L + S + + VAL E+YKYI KY+D+I+ LE + ++ Q
Sbjct: 1499 EMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQ 1549
Score = 97.4 bits (241), Expect = 1e-19
Identities = 149/637 (23%), Positives = 244/637 (38%), Gaps = 102/637 (16%)
Query: 78 DCLPPVMPDECPQAQPTNNPNQLLL------VSPGALVVCG-SVHQGVCEQRRLGQLEQL 130
+C PV + +P ++ ++LLL G L++ G + +G CE R LG L +
Sbjct: 86 NCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRN 145
Query: 131 LLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW 190
LR T+ V+ + P ST G+V + AG R Y + +P T +
Sbjct: 146 SLR----NGTEVVSCH-PQGSTAGVVYR--AGRN----NRWYLAVAATYVLPEPETASRC 194
Query: 191 PP---DPQAAFSYEET-----AKLAVGRLS----EYSHHFVSAFARGASAYFLFLRRDLQ 238
P D A + ++T A +GRL S HFV AF S YF + +
Sbjct: 195 NPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYPYNYT 254
Query: 239 AQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYG---LIQAAAVATSREVAHGEVLFA 295
+ + ++R+ + + + L C G L+ ++++ + +V G
Sbjct: 255 SGAATGWPSMARIAQSTEVLFQG-QASLDCGHGHPDGRRLLLSSSLVEALDVWAG----- 308
Query: 296 AFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
FS+AA R +ALC F + E+ A R T E ++G +
Sbjct: 309 VFSAAAGEGQERRSPTT------TALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQPER 362
Query: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
++ P+AS + + LT+V T+
Sbjct: 363 VQ---------------------------PIASSTLIHS---------DLTSVYGTVVMN 386
Query: 416 HTIAFLGDSQGQLHRVYLGPGSDGH-PYSTQSIQQGSAVSRDLTFDGTFE-HLYVMTQST 473
T+ FLG GQL +V LG + P I++ + V L D ++Y+
Sbjct: 387 RTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKE 446
Query: 474 LLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGC 533
+ ++ VA+C +H C+ CL DP+CGWC L RC+ + +C + E WL G
Sbjct: 447 VRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWL---DISSGA 503
Query: 534 LQVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDP 593
+ + S+E+T +V + P S S L P+
Sbjct: 504 KKCPKIQIIRSSKEKT-----TVTMVGSFSPRHSKCMVKNVDSSRELCQNKS----QPNR 554
Query: 594 SEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNW 653
+ +P A Y VSV V+ + S + D T +C ACV + GC W
Sbjct: 555 TCTCSIPTRATYKDVSVV----NVMFSFGSWNLSDRFNFTNCSSLKECPACVET--GCAW 608
Query: 654 CVWQHLCTHK-ASCDAGPMVASHQSPLVSPDPPARGG 689
C C H +CD + + V+ + + GG
Sbjct: 609 CKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGG 645
>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
Length = 522
Score = 119 bits (299), Expect = 2e-26
Identities = 111/434 (25%), Positives = 198/434 (45%), Gaps = 52/434 (11%)
Query: 37 HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ-AQPTN 95
HL D +G +YLGA N +++LS L++ T TGP D+ C PP + C + TN
Sbjct: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
Query: 96 NPNQLLLV--SPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153
N N++LL+ L+ CGS++QG+C+ RL L + L P + Y++ + + S
Sbjct: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFK-LGEPYHKKE-HYLSGVNESGSVF 170
Query: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW---PPDPQAAFSYEETAKLAVGR 210
G++ + LF+ G P I++R L D A+ + + ++ +
Sbjct: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228
Query: 211 --------LSEYSHHFVSAFARGASAYFLFLRRDL------QAQSRAFRAYVSRVCLRDQ 256
+ ++ ++V F+ G YFL L+ ++ + + + + + R+C D
Sbjct: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288
Query: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREV--------AHGEVLFAAFSSAAPPTVG 306
+ SYVE+P+ CE G Y L+QAA ++ + V ++LF FS
Sbjct: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFS-------- 340
Query: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365
+ + SALC F L +++ +CY R E ++A+++ D+ A
Sbjct: 341 KGQKRKMKSLDESALCIFILKQINDRIKERLQSCY----RGEGTLDLAWLKVKDIPCSSA 396
Query: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425
L T+D CG D +P+ + P+ ++T+V + H++AF+G
Sbjct: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452
Query: 426 GQLHRVYLGPGSDG 439
G+L + + G G G
Sbjct: 453 GKLKKSF-GTGPQG 465
>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
Length = 492
Score = 119 bits (297), Expect = 4e-26
Identities = 114/445 (25%), Positives = 203/445 (45%), Gaps = 56/445 (12%)
Query: 37 HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ-AQPTN 95
HL D +G +YLGA N +++LS L++ T TGP D+ C PP + C + TN
Sbjct: 53 HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
Query: 96 NPNQLLLV--SPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153
N N++LL+ L+ CGS++QG+C+ RL L + L P + Y++ + + S
Sbjct: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFK-LGEPYHKKE-HYLSGVNESGSVF 170
Query: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW---PPDPQAAFSYEETAKLAVGR 210
G++ + LF+ G P I++R L D A+ + + ++ +
Sbjct: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228
Query: 211 --------LSEYSHHFVSAFARGASAYFLFLRRDL------QAQSRAFRAYVSRVCLRDQ 256
+ ++ ++V F+ G YFL L+ ++ + + + + + R+C D
Sbjct: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288
Query: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREV--------AHGEVLFAAFSSAAPPTVG 306
+ SYVE+P+ CE G Y L+QAA ++ + V ++LF FS
Sbjct: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFS-------- 340
Query: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365
+ + SALC F L +++ +CY R E ++A+++ D+ A
Sbjct: 341 KGQKRKMKSLDESALCIFILKQINDRIKERLQSCY----RGEGTLDLAWLKVKDIPCSSA 396
Query: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425
L T+D CG D +P+ + P+ ++T+V + H++AF+G
Sbjct: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452
Query: 426 GQLHRVYLGPGSDGHPYSTQSIQQG 450
G+L ++ PG+ P T +Q G
Sbjct: 453 GKLKKM---PGTSLCP--TLELQTG 472
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 117 bits (292), Expect = 2e-25
Identities = 116/419 (27%), Positives = 177/419 (42%), Gaps = 54/419 (12%)
Query: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRV 1088
CS+C +A P C WC +CV E C C P I+ V P + P++GGTR+
Sbjct: 526 CSQCLSAPPFVQCGWCHD---KCVRSEECLSGTWTQQIC-LPAIYKVFPNSAPLEGGTRL 581
Query: 1089 TIRGSNLGQHVQDVLGM----VTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVE 1144
TI G + G + + V + C + E ++L C G + + + +
Sbjct: 582 TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSE-STMNTLKCTVGPAMNKHFNMSIII 640
Query: 1145 VPGRGRGVSEHD-FAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQP 1203
G G +++ F+Y DP + SI P GP AGGT LTL G+ L +G I +G +
Sbjct: 641 --SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHIS--IGGKT 696
Query: 1204 CHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSF 1263
C L + L C T + V + R + F Y DP + PTKSF
Sbjct: 697 C-TLKSVSNSILECYTPAQTISTEFAVKLKIDLANR--ETSIFSYREDPIVYEIHPTKSF 753
Query: 1264 LSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQF 1323
+SGG I G+NL+ V PR+ + V GR V AC
Sbjct: 754 ISGGSTITGVGKNLNSVSVPRMVINV--------HEAGRNFTV----ACQ---------- 791
Query: 1324 EEPCHVNSSQLITCRTPALPGLPEDPWVRVE--FILDNLVFDFATLNPTPFSYEADPTLQ 1381
H ++S++I C TP+L L ++ + F+LD ++ + L Y +P +
Sbjct: 792 ----HRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDL-----IYVHNPVFK 842
Query: 1382 PLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
P E P M +V ++G ++D K EV+ +G+ C L + C P
Sbjct: 843 PF--EKPVM-ISMGNENVLEIKGNDIDPEAVKGEVL-KVGNKSCENIHLHSEAVLCTVP 897
Score = 88.2 bits (217), Expect = 8e-17
Identities = 131/545 (24%), Positives = 215/545 (39%), Gaps = 116/545 (21%)
Query: 47 LYLGATNFLFQLSP-GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPT-----NNPNQL 100
++LGATN+++ L+ LQ A TGPVL+ DC P D +A + +N N
Sbjct: 62 IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP--CQDCSSKANLSGGVWKDNINMA 119
Query: 101 LLVSP---GALVVCGSVHQGVCEQRRLGQLEQLLLRPE-----RPGDTQYVAANDPAVST 152
L+V L+ CGSV++G C++ ++ E P + D VS
Sbjct: 120 LVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSA 179
Query: 153 VGLVAQGLAGEPLL--FVGRGYTSRGVGGG-IPPITTRALWPPDPQAAFSYEETAKLAVG 209
+G + + FVG S + I+ R L F +++ +
Sbjct: 180 LGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLP 239
Query: 210 RLSE-YSHHFVSAFARGASAYFLFLRRD-LQAQSRAFRAYVSRVCLRDQHYYSYVELPLA 267
+ Y +V AF YFL ++R+ L AQ+ F + R C + +SY+E+PL
Sbjct: 240 EFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQT--FHTRIIRFCSINSGLHSYMEMPLE 297
Query: 268 C-----------EGGRYGLIQAAAVAT-----SREVA---HGEVLFAAFSSAAPPTVGRP 308
C + + ++QAA V+ +R++ + ++LF F+ + P +
Sbjct: 298 CILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDS---- 353
Query: 309 PSAAAGASGASALCAFPLDEVDRLANR----------------TRDACYTREG-RAEDGT 351
A SA+CAFP+ V+ N+ + C+ R R G
Sbjct: 354 ----AEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGC 409
Query: 352 EVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVT 411
E EY A VD ++ + LT+++
Sbjct: 410 EARRDEYRTEFTTALQRVDLFMG------------------------QFSEVLLTSISTF 445
Query: 412 MEDGHTIAFLGDSQGQLHRVYL---GPGS-------DGHPYSTQSIQQGSAVSRDLTFDG 461
++ TIA LG S+G+ +V + GP + D HP S + I V L +G
Sbjct: 446 IKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVI-----VEHTLNQNG 500
Query: 462 TFEHLYVMTQSTLLKVPV--ASCAQHLDCASCLAHRDPY--CGWCVLLGRCSRRSECSRG 517
+ V+T + K+P+ C C+ CL+ P+ CGWC +C R EC G
Sbjct: 501 ---YTLVITGKKITKIPLNGLGCRHFQSCSQCLS-APPFVQCGWC--HDKCVRSEECLSG 554
Query: 518 QGPEQ 522
+Q
Sbjct: 555 TWTQQ 559
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 105 bits (263), Expect = 4e-22
Identities = 116/437 (26%), Positives = 177/437 (40%), Gaps = 72/437 (16%)
Query: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRV 1088
CS+C +A P C WC +CV E C C P I+ V P + P++GGTR+
Sbjct: 526 CSQCLSAPPFVQCGWCHD---KCVRSEECLSGTWTQQIC-LPAIYKVFPNSAPLEGGTRL 581
Query: 1089 TIRGSNLGQHVQDVLGM----VTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVE 1144
TI G + G + + V + C + E ++L C G + + + +
Sbjct: 582 TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSE-STMNTLKCTVGPAMNKHFNMSIII 640
Query: 1145 VPGRGRGVSEHD-FAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQP 1203
G G +++ F+Y DP + SI P GP AGGT LTL G+ L +G I +G +
Sbjct: 641 --SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHIS--IGGKT 696
Query: 1204 CHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSF 1263
C L + L C T + V + R + F Y DP + PTKSF
Sbjct: 697 C-TLKSVSNSILECYTPAQTISTEFAVKLKIDLANR--ETSIFSYREDPIVYEIHPTKSF 753
Query: 1264 L------------------SGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRR 1305
+ SGG I G+NL+ V PR+ + V GR
Sbjct: 754 ISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINV--------HEAGRNFT 805
Query: 1306 VVPETACSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVE--FILDNLVFD 1363
V AC H ++S++I C TP+L L ++ + F+LD ++
Sbjct: 806 V----ACQ--------------HRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSK 847
Query: 1364 FATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDG 1423
+ L Y +P +P E P M +V ++G ++D K EV+ +G+
Sbjct: 848 YFDL-----IYVHNPVFKPF--EKPVM-ISMGNENVLEIKGNDIDPEAVKGEVL-KVGNK 898
Query: 1424 PCVVKTLTRHHLYCEPP 1440
C L + C P
Sbjct: 899 SCENIHLHSEAVLCTVP 915
Score = 88.2 bits (217), Expect = 8e-17
Identities = 131/545 (24%), Positives = 215/545 (39%), Gaps = 116/545 (21%)
Query: 47 LYLGATNFLFQLSP-GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPT-----NNPNQL 100
++LGATN+++ L+ LQ A TGPVL+ DC P D +A + +N N
Sbjct: 62 IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP--CQDCSSKANLSGGVWKDNINMA 119
Query: 101 LLVSP---GALVVCGSVHQGVCEQRRLGQLEQLLLRPE-----RPGDTQYVAANDPAVST 152
L+V L+ CGSV++G C++ ++ E P + D VS
Sbjct: 120 LVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSA 179
Query: 153 VGLVAQGLAGEPLL--FVGRGYTSRGVGGG-IPPITTRALWPPDPQAAFSYEETAKLAVG 209
+G + + FVG S + I+ R L F +++ +
Sbjct: 180 LGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLP 239
Query: 210 RLSE-YSHHFVSAFARGASAYFLFLRRD-LQAQSRAFRAYVSRVCLRDQHYYSYVELPLA 267
+ Y +V AF YFL ++R+ L AQ+ F + R C + +SY+E+PL
Sbjct: 240 EFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQT--FHTRIIRFCSINSGLHSYMEMPLE 297
Query: 268 C-----------EGGRYGLIQAAAVAT-----SREVA---HGEVLFAAFSSAAPPTVGRP 308
C + + ++QAA V+ +R++ + ++LF F+ + P +
Sbjct: 298 CILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDS---- 353
Query: 309 PSAAAGASGASALCAFPLDEVDRLANR----------------TRDACYTREG-RAEDGT 351
A SA+CAFP+ V+ N+ + C+ R R G
Sbjct: 354 ----AEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGC 409
Query: 352 EVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVT 411
E EY A VD ++ + LT+++
Sbjct: 410 EARRDEYRTEFTTALQRVDLFMG------------------------QFSEVLLTSISTF 445
Query: 412 MEDGHTIAFLGDSQGQLHRVYL---GPGS-------DGHPYSTQSIQQGSAVSRDLTFDG 461
++ TIA LG S+G+ +V + GP + D HP S + I V L +G
Sbjct: 446 IKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVI-----VEHTLNQNG 500
Query: 462 TFEHLYVMTQSTLLKVPV--ASCAQHLDCASCLAHRDPY--CGWCVLLGRCSRRSECSRG 517
+ V+T + K+P+ C C+ CL+ P+ CGWC +C R EC G
Sbjct: 501 ---YTLVITGKKITKIPLNGLGCRHFQSCSQCLS-APPFVQCGWC--HDKCVRSEECLSG 554
Query: 518 QGPEQ 522
+Q
Sbjct: 555 TWTQQ 559
>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
sapiens]
Length = 1400
Score = 84.7 bits (208), Expect = 9e-16
Identities = 77/272 (28%), Positives = 110/272 (40%), Gaps = 34/272 (12%)
Query: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRV 1088
C RC A GC WC C ++ C CP P + P +GP+ G TR+
Sbjct: 533 CGRCLRAWHFMGCGWCGN---MCGQQKEC-PGSWQQDHCP-PKLTEFHPHSGPLRGSTRL 587
Query: 1089 TIRGSNLGQH----VQDVLGMVTVAGVPCAVDAQEY---------EVSSSLVCITGASGE 1135
T+ GSN H V + VTV PC ++ + C G
Sbjct: 588 TLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFECELEPLGT 647
Query: 1136 EVAGATAVEVPGRGRGVSEH----------DFAYQDPKVHSIFPARGPRAGGTRLTLNGS 1185
+ G T V + +H F++ +P + ++ P GPRAGGT LTL G
Sbjct: 648 QAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCLTLEGQ 707
Query: 1186 KLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQ 1245
L G V+V C LL QL C T P T A++P+++ G +
Sbjct: 708 SLSVGTSR--AVLVNGTEC-LLARVSEGQLLCATPPGATVASVPLSLQVGGAQVP-GSWT 763
Query: 1246 FKYTLDPNITSAGPTKSFLSGGREICVRGQNL 1277
F+Y DP + S P +++ IC GQ+L
Sbjct: 764 FQYREDPVVLSISPNCGYINSHITIC--GQHL 793
Score = 82.8 bits (203), Expect = 3e-15
Identities = 148/584 (25%), Positives = 218/584 (37%), Gaps = 90/584 (15%)
Query: 41 DPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQL 100
D +++ N L L P L+ +++TGP D C P P + ++
Sbjct: 64 DRNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGDP-GCQTCAACGPGPHGPPGDTDTKV 122
Query: 101 LLVSPG--ALVVCGSVHQGVCEQRRL---GQLEQLLL-------RPERPGDTQYVAANDP 148
L++ P ALV CGS QG C L G L RP D A+ P
Sbjct: 123 LVLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDCPDCVAS-P 181
Query: 149 AVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPP--ITTRALWPPDPQAAFSYEETAKL 206
+ V +V QG A F V P ++ R L A + + L
Sbjct: 182 LGTRVTVVEQGQAS---YFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVALSVL 238
Query: 207 AVGRLSEYSHHFVSAFARGASAYFLFLR-RDLQAQSRAFRAYVSRVCLRDQHYYSYVELP 265
L YS +V +F GA YFL ++ + A ++R+ + Y EL
Sbjct: 239 PK-HLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPELGDYRELV 297
Query: 266 LAC------------EGGR-YGLIQAA-------AVATSREVAHG-EVLFAAFSSAAPPT 304
L C EGG+ Y +++ A +AT +A G EVLF F +
Sbjct: 298 LDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVFVTGKDGG 357
Query: 305 VGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDVNSDC 364
G P+ S +CAFP+D +D L + + C E G + S C
Sbjct: 358 PGVGPN--------SVVCAFPIDLLDTLIDEGVERCC--ESPVHPGLRRGLDFFQSPSFC 407
Query: 365 AQLPVDTLDAYPCGSDHTP---SPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFL 421
P + H P S SRV L + +Q+TA+ VT D T+A +
Sbjct: 408 PNPPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLL---GPVQVTALYVTRLDNVTVAHM 464
Query: 422 GDSQGQLHRVYLGPGSDGHPY-STQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPV 479
G G++ +V L + Y S S+ G V RD++ G +HL + + +VP+
Sbjct: 465 GTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVSRLG--DHLLFASGDQVFQVPI 522
Query: 480 --ASCAQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQW--------LWSFQ 528
C L C CL A CGWC C ++ EC P W L F
Sbjct: 523 QGPGCRHFLTCGRCLRAWHFMGCGWCG--NMCGQQKEC-----PGSWQQDHCPPKLTEFH 575
Query: 529 PELGCLQVAA----------MSPANISREETREVFLSVPDLPPL 562
P G L+ + + P+ + E T +V + PL
Sbjct: 576 PHSGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPL 619
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 79.3 bits (194), Expect = 4e-14
Identities = 67/226 (29%), Positives = 94/226 (41%), Gaps = 34/226 (15%)
Query: 684 PPARGGPSP---SPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWG--- 737
PP +G P+ +PP+ LATP+P GAP+T A+ SP + SP G
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPK------GAPTTPAATPPSPKGGLATPSPKGAPT 1219
Query: 738 -----PWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDL---LA 789
P + G +++P G+P +PPSP+ GP T P P+ATP L LA
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279
Query: 790 SPL---SPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREG 846
+P +P+ PP+ G A P PPA P + G+ G+ P +G
Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP-KGSPGTPPP-------KG 1331
Query: 847 GELPEA---DEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPS 889
P A G +T + G + EGP P PS
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377
Score = 72.4 bits (176), Expect = 4e-12
Identities = 68/239 (28%), Positives = 96/239 (40%), Gaps = 37/239 (15%)
Query: 668 AGPMVASHQSPLVSPDPPARGGPS-PSPPTAPKALATPAPD-----TLPVEPGAPSTATA 721
A P + +P + P +GGP+ PSP AP A P P GAP+T A
Sbjct: 1072 ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131
Query: 722 SDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPS 781
+ SP G +++P G+P +PPSP+ G T P P+
Sbjct: 1132 TPPSP---------------KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176
Query: 782 AT---PEDLLASPL---SPSEVAAVPP------ADPGPEALHPTVPLDLPPATVPATTFP 829
AT P+ LA+P +P+ AA PP A P P+ PT P PP+ P
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA-PTTPAATPPSPKGGLATP 1235
Query: 830 GAMGS-VKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLIL 887
G+ PA + +GG P G P +T L G + +G P P ++
Sbjct: 1236 SPKGAPTTPAATPPSPKGG--PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
Score = 71.6 bits (174), Expect = 8e-12
Identities = 74/233 (31%), Positives = 94/233 (40%), Gaps = 34/233 (14%)
Query: 681 SPDPPA-RGGPSPSP--PTAPKALATPAPDT-------LPVEPGAPSTATASDISPGASP 730
SP PP+ +G P+PS P +PK + P +T LP P+T +P S
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ-APALSM 913
Query: 731 SLLSPW---GPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDL 787
+ SP A G +SP G+P +PPSP+ GP T P P+ATP
Sbjct: 914 TSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP 973
Query: 788 LASPLSPS------EVAAVPPADPGPEALHPTVPLDLPPATVP--------ATTFPGAMG 833
P +PS AA PP+ G A PPA P AT FP
Sbjct: 974 KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG-A 1032
Query: 834 SVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSA--ELEGPPAP 884
S PA + +G P A G AP +TL S G A L+G P P
Sbjct: 1033 STPPAATPPSPKGS--PAATPLPKG-APTTPAATLPSPKGGPATPSLKGAPTP 1082
Score = 67.8 bits (164), Expect = 1e-10
Identities = 61/201 (30%), Positives = 83/201 (41%), Gaps = 37/201 (18%)
Query: 670 PMVASHQSPLVSPDPPA-RGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGA 728
P A+ SP P P+ +G P+P T P +PA P GA + A+ SP
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA--ATPFPKGASTPPAATPPSPKG 1045
Query: 729 SPSLL-----SPWGPWA----GSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFR 779
SP+ +P P A G ++P G+P +PPSP+ GP T P
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP 1105
Query: 780 PSAT---PEDLLASPL---SPSEVAAVPPADPG-----PEALHPTVPLDLPPA------- 821
P+AT P+ LA+P +P+ AA PP+ G P PT P PP+
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165
Query: 822 -------TVPATTFPGAMGSV 835
T PA T P G +
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGL 1186
Score = 67.4 bits (163), Expect = 1e-10
Identities = 69/230 (30%), Positives = 87/230 (37%), Gaps = 35/230 (15%)
Query: 684 PPARGGPSPSP----PTAPKALATPAPDTLPVEPGAPSTATASDISPGASPS-LLSPWGP 738
PPA PSP PT +A ATP+ E +P T S SP LL P
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSK----EASSPPAVTPSTYKGAPSPKELLIP--- 1602
Query: 739 WAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEV- 797
+++SP +P +PPSP+ GP T P T P TP L SP SP+ V
Sbjct: 1603 ----PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVT 1658
Query: 798 ----AAVP------PADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGG 847
A VP PA GP AL + P +T P T P G +
Sbjct: 1659 CKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST-PIITAPTRKGPQTKKSSATSPPIC 1717
Query: 848 ELPEADEWTGGDAPAFSTSTLLSGDGDSAEL-------EGPPAPLILPSS 890
P A + G + + LL DS++ P PL P S
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPES 1767
Score = 62.8 bits (151), Expect = 4e-09
Identities = 57/181 (31%), Positives = 77/181 (42%), Gaps = 28/181 (15%)
Query: 672 VASHQSPLVSPDPPA------RGGP-SPSPPTA--PKALATPAPDTLPVEP---GAPSTA 719
+ + SP +P PPA +GGP +PSP A P A P+P P P GAP+
Sbjct: 930 IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989
Query: 720 TASDISPGASPSLLSPWG--------PWAGSGS-ISSPGSTGSPLHEEPSPPSPQNGP-G 769
A+ SP P+ SP G P + GS ++P G+ +PPSP+ P
Sbjct: 990 AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049
Query: 770 TAVPAPTDFRPSATPEDLLASPLSPS------EVAAVPPADPGPEALHPTVPLDLPPATV 823
T +P P+AT P +PS AA PP+ G A +PPA
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT 1109
Query: 824 P 824
P
Sbjct: 1110 P 1110
Score = 62.8 bits (151), Expect = 4e-09
Identities = 53/212 (25%), Positives = 72/212 (33%), Gaps = 43/212 (20%)
Query: 680 VSPDPPARGGPSPS---PPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPW 736
+ P +G P+P PP+ ATP+P P P A
Sbjct: 930 IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT-------------------- 969
Query: 737 GPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSP-- 794
P + G ++P G+P +PPSP+ GP T P P+ TP SP +
Sbjct: 970 -PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 795 SEVAAVPPA--DPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEA 852
+ A+ PPA P P+ PL T PA T P G P
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---------------PAT 1073
Query: 853 DEWTGGDAPAFSTSTLLSGDGDSAELEGPPAP 884
G P +T G + +G P P
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMP 1105
Score = 59.7 bits (143), Expect = 3e-08
Identities = 69/242 (28%), Positives = 95/242 (39%), Gaps = 45/242 (18%)
Query: 677 SPLVSPDPPARGGPSPSPPTA---PKALATPAPDTLPVEP---GAPSTATASDISPGASP 730
+P V P +GGP+ SPP P A P+P P P GAP+ + SP +P
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347
Query: 731 SL-----LSPWGPWAGSGS------ISSPGSTGSPLHEEPSP------PSPQNGPGTAVP 773
+L S GP S ++P G P PSP PSP+ P + P
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS--P 1405
Query: 774 APTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATV-----PATTF 828
A P P A+P++ A D P A+ P V L PAT PAT
Sbjct: 1406 AVIPLSPKKAP----ATPVTREGAATPSKGDLTPPAVTP-VSLKKAPATSAPKGGPAT-- 1458
Query: 829 PGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILP 888
P + G P L +T + P A + ++S+ A + P P ++P
Sbjct: 1459 PSSKGD--PTLPAVTPPSPKEPPAPKQVA------TSSSPKKAPATPAPMGAPTLPAVIP 1510
Query: 889 SS 890
SS
Sbjct: 1511 SS 1512
Score = 59.7 bits (143), Expect = 3e-08
Identities = 71/253 (28%), Positives = 91/253 (35%), Gaps = 37/253 (14%)
Query: 665 SCDAGPMVASHQSPLVSPDPPA-----RGGPSPSPPTAPKALATPAPDTLPVEPG----- 714
S GP S + P PPA +GGP+ +PP+ + A P+P P P
Sbjct: 1355 SSKGGPTTPSSKE---GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411
Query: 715 ---APST-------ATAS--DISPGASP--SLLSPWGPWAGSGSISSPGSTGSPLHEEPS 760
AP+T AT S D++P A SL A G ++P S G P +
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 761 PPSPQNGPG--------TAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHP 812
PPSP+ P + AP P P P SP EV A P + P A
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 813 TVPLDLPPATV--PATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLS 870
T+ PAT+ P AM P E P +P T +
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591
Query: 871 GDGDSAELEGPPA 883
G EL PPA
Sbjct: 1592 GAPSPKELLIPPA 1604
Score = 50.1 bits (118), Expect = 2e-05
Identities = 65/242 (26%), Positives = 91/242 (37%), Gaps = 31/242 (12%)
Query: 670 PMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPG-APSTATASDISPGA 728
P + SP +P PPA +PP+ K ATPAP P P PS+ S SP +
Sbjct: 1602 PPAVTSPSPKEAPTPPAV-----TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656
Query: 729 SPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLL 788
+ P A G + G T L E P+P++ P + APT P
Sbjct: 1657 VTCKMGATVPQASKGLPAKKGPTA--LKEVLVAPAPESTP--IITAPTRKGPQTKKSSAT 1712
Query: 789 ASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGE 848
+ P+ P A GP + PL LP + T G S P G
Sbjct: 1713 SPPICPDPSA--KNGSKGPLSTVAPAPL-LPVQKDSSKTAKGKDASHSPK--------GP 1761
Query: 849 L--PEADEWTGGDAPAF-------STSTLLSGDGDSAELEGPPAPL-ILPSSLDYQYDTP 898
L PE+ T A AF ++++ + L P+P+ LP + +P
Sbjct: 1762 LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSP 1821
Query: 899 GL 900
GL
Sbjct: 1822 GL 1823
Score = 49.7 bits (117), Expect = 3e-05
Identities = 45/154 (29%), Positives = 62/154 (40%), Gaps = 16/154 (10%)
Query: 670 PMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPD-TLPVEPGAPSTATASDISPGA 728
P + SP +P PA S PT P + P P P G P+ SP
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP---SPKR 1391
Query: 729 SPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSA-TPEDL 787
P++ SP G +SP PL + +P +P G A P+ D P A TP L
Sbjct: 1392 GPAIPSP------KGDPTSPAVI--PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443
Query: 788 LASPLSPSEVAAVPPADPGPEALHPTVPLDLPPA 821
+P + + PA P + PT+P PP+
Sbjct: 1444 KKAPATSAPKGG--PATPSSKG-DPTLPAVTPPS 1474
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/150 (29%), Positives = 60/150 (40%), Gaps = 32/150 (21%)
Query: 673 ASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSL 732
+S SP + PDP A+ G P + PAP LPV+ + TA D S
Sbjct: 1709 SSATSPPICPDPSAKNGSK-----GPLSTVAPAP-LLPVQKDSSKTAKGKDASH------ 1756
Query: 733 LSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPL 792
SP GP A S +S T + + +P P SA P ++ PL
Sbjct: 1757 -SPKGPLAPPESKASTPLTAAAFEK-------------VLPKPESASVSAAPSPPVSLPL 1802
Query: 793 SPSEVAAVP------PADPGPEALHPTVPL 816
+PS V +P P+ PG P+ PL
Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVLESPSKPL 1832
Score = 45.4 bits (106), Expect = 6e-04
Identities = 54/204 (26%), Positives = 73/204 (35%), Gaps = 32/204 (15%)
Query: 683 DPPARGGPSPSPPTA--PKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWA 740
D P+ G S SP T P + PDT P +S +SP + L P +
Sbjct: 792 DSPSPLGVSVSPQTKRPPTKKGSAGPDT-------PIGNLSSPVSPVEASFL--PENSLS 842
Query: 741 GSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAV 800
GS SP +T S P+PPSP+ P PSA +PLSP V
Sbjct: 843 FQGSKDSPATTHS-----PTPPSPKGAP----------TPSA------VTPLSPKGVTLP 881
Query: 801 PPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDA 860
P P P ++ P + P P +M S P T +P + G
Sbjct: 882 PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT 941
Query: 861 PAFSTSTLLSGDGDSAELEGPPAP 884
P +T G + + P P
Sbjct: 942 PPAATPPSPKGGPATPSPKWAPTP 965
Score = 42.4 bits (98), Expect = 0.005
Identities = 68/236 (28%), Positives = 91/236 (38%), Gaps = 24/236 (10%)
Query: 673 ASHQSPLVSPDPPARGGPSPS---PPTAPKALATPAPDTLPVEPGAPST---ATASDISP 726
AS P V+P P P + P PK++ +P+ PG + S ++P
Sbjct: 704 ASENCP-VAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762
Query: 727 GASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSA---T 783
AS P S + SS G T + L + PSP P T P PT + SA T
Sbjct: 763 VASSPKECPTEDSGASATASSKG-TLTYLADSPSPLGVSVSPQTKRP-PTK-KGSAGPDT 819
Query: 784 PEDLLASPLSPSEVAAVPP-------ADPGPEALH-PTVPLDLPPATVPATTFPGAMGSV 835
P L+SP+SP E + +P + P H PT P T A T G
Sbjct: 820 PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879
Query: 836 KPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDS-AELEGPPAPLILPSS 890
P + T LP E G PA + LS S + PAP +P+S
Sbjct: 880 LPPKETPTPSVVNLPFPKE--GPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933
Score = 37.7 bits (86), Expect = 0.12
Identities = 51/223 (22%), Positives = 89/223 (39%), Gaps = 18/223 (8%)
Query: 688 GGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWAGSGSIS- 746
G + + P + L P +T + + + TA+ PG P+L P P +S
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLSA 60
Query: 747 ----SPGSTGSPLHEEP-SPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVA--- 798
SP + S + P P PQ+ GTA+P T +L+ P+SP+ +A
Sbjct: 61 ANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS 120
Query: 799 --AVPPADPGPEALHPTVPLDLPPATV-PATTFPGAMGSVKPALDWLTREGGELPEADEW 855
P P + P + L P +V ++ FP + + P++ E G +
Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSV--AVAESGSVITLSAP 178
Query: 856 TGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTP 898
P + + + S + +G P+P + S++ Y TP
Sbjct: 179 IAPSEPKTNLNKVPSEVVPNP--KGTPSPPCIVSTVPYHCVTP 219
Score = 37.7 bits (86), Expect = 0.12
Identities = 41/160 (25%), Positives = 54/160 (33%), Gaps = 33/160 (20%)
Query: 661 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720
T+ + A P + VSP P + G S PT+P AL PV P PST
Sbjct: 444 TNPCTIAAAPTTTFEVATCVSP-PMSSGPISNIEPTSPAALVMA-----PVAPKEPSTQV 497
Query: 721 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTA-VPAPTDFR 779
A+ + SP L P P +N P + V PT
Sbjct: 498 ATTLRIPVSPPL--------------------------PDPEDLKNLPSSVLVKFPTQKD 531
Query: 780 PSATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLP 819
P L +P SP++ DP L P + P
Sbjct: 532 LQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSP 571
Score = 32.7 bits (73), Expect = 3.9
Identities = 66/274 (24%), Positives = 98/274 (35%), Gaps = 60/274 (21%)
Query: 669 GPMVASHQSPLVSP--DPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISP 726
GP ++ L SP P +G PS S P A AL AP + S P
Sbjct: 108 GPPISPAALALASPMIAPTLKGTPSSSAPLALVAL-------------APHSVQKSSAFP 154
Query: 727 GASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPED 786
P+LL +SP PS ++G + AP PS +
Sbjct: 155 ---PNLL------------TSP----------PSVAVAESGSVITLSAP--IAPSEPKTN 187
Query: 787 LLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREG 846
L PSEV P P P + TVP P + + S+ P T
Sbjct: 188 L---NKVPSEVVPNPKGTPSPPCIVSTVPYH---CVTPMASIQSGVASL-PQTTPTTTLA 240
Query: 847 GELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGLWELEEA 906
P+ + T S+ + + S L+GP +P P++L + + +
Sbjct: 241 IASPQVKDTT------ISSVLISPQNPGSLSLKGPVSP---PAALSLSTQSLPVVTSSQK 291
Query: 907 TLGASSCPCVESVQGSTLMPVHVER--EIRLLGR 938
T G ++ P GS L P+H ++LLG+
Sbjct: 292 TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQ 325
Score = 32.0 bits (71), Expect = 6.7
Identities = 39/154 (25%), Positives = 57/154 (37%), Gaps = 5/154 (3%)
Query: 685 PARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSL-LSPWGPWAGSG 743
PA +P P P LP+ AP + + S +SP + LSP A
Sbjct: 536 PASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQ-STSSSPEIPLSPEATLAKK- 593
Query: 744 SISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPA 803
S+ P G P SP N + + + P + L +S ++P+ VAA P
Sbjct: 594 SLGEPLPIGKPASSMTSPLGV-NSSASVIKTDSYAGPDSAGPLLKSSLITPT-VAAFPLE 651
Query: 804 DPGPEALHPTVPLDLPPATVPATTFPGAMGSVKP 837
P + PT T A+ F S+ P
Sbjct: 652 SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAP 685
Score = 31.6 bits (70), Expect = 8.7
Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 13/137 (9%)
Query: 681 SPDPPARG--GPSPSPPTAPKALATPAPDTLPVE-PGAP-STATASDISPGASPSLLSPW 736
+P PP PSP P PK P+ L +E P P + A ++ P P +S
Sbjct: 1793 APSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGG 1852
Query: 737 GPWAG-SGSISSPGSTGSPLHEEPSP----PSPQNGPGTAVPAPTDFR-PSATPEDLLAS 790
P+ ++ +P S G P+ P+P P +N G+ + +D P +D +
Sbjct: 1853 VPFQSVLVNMPTPKSAGIPV---PTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQA 1909
Query: 791 PLSPSEVAAVPPADPGP 807
+++AA D P
Sbjct: 1910 TTQQAQLAAAAEIDEEP 1926
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 69.3 bits (168), Expect = 4e-11
Identities = 74/234 (31%), Positives = 96/234 (41%), Gaps = 27/234 (11%)
Query: 660 CTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTA 719
C+H + + H VSP PP+ P PPT P P +LP EP + S A
Sbjct: 121 CSHSSPGEGASPQMFHT---VSPGPPSARPPCRVPPTTP---LNGGPGSLPPEPPSVSQA 174
Query: 720 TASDISPGA--SPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPT- 776
+ PG P L P SG SSP P+PP P P ++ AP+
Sbjct: 175 FPTLAGPGGLFPPRLADP----VPSGGSSSPRFLPRGNAPSPAPPPP---PAISLNAPSY 227
Query: 777 ----DFRPSATPEDLLASPLSPSEVAAVPPADPGP-EALHPTVPLDLPPAT-VPATTFPG 830
R S P DL SP +P ++ PP+DP P LPP+ +PA P
Sbjct: 228 NWGAALRSSLVPSDL-GSPPAP-HASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPA 285
Query: 831 AMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAP 884
+ V A L G L A G AP F S+LLS +A+ + PP P
Sbjct: 286 SQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSA---AAKAQHPPLP 336
Score = 53.5 bits (127), Expect = 2e-06
Identities = 57/211 (27%), Positives = 76/211 (36%), Gaps = 22/211 (10%)
Query: 678 PLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWG 737
P P PP G P +L P P L P AP + + P L G
Sbjct: 579 PPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLP------LLALG 632
Query: 738 PWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEV 797
P AG G S+ G+ G PS + G +P F P + P L+A +
Sbjct: 633 PTAGDGEGSAEGAGG---------PSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAA 683
Query: 798 AAVPPADPGPEALHPTVPLDLPP--ATVPATTFPGAMGSVKPALDWLTREGGELPEADEW 855
PP+ P+ + P PP + ATT PGA +L G P+
Sbjct: 684 TLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGA-----SSLGKAPSNSGRPPQLLSP 738
Query: 856 TGGDAPAFSTSTLLSGDGDSAELEGPPAPLI 886
G + S+L S G L PP PL+
Sbjct: 739 LLGASLLGDLSSLTSSPGALPSLLQPPGPLL 769
Score = 45.4 bits (106), Expect = 6e-04
Identities = 50/164 (30%), Positives = 56/164 (34%), Gaps = 31/164 (18%)
Query: 682 PDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWAG 741
P P P P PPT+ AT +PGA S A S G P LLSP +
Sbjct: 693 PQPCVLSAPQPGPPTSSVTTAT-------TDPGASSLGKAPSNS-GRPPQLLSPLLGASL 744
Query: 742 SGSISSPGSTGSPLHEEPSPPSP--------QNGPGTAVPAPTDFR-------------P 780
G +SS S+ L PP P Q PG P P P
Sbjct: 745 LGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIP 804
Query: 781 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVP 824
PE P SP+ PA P AL P P P VP
Sbjct: 805 PEQPEAPCLPPESPASALEPEPARPPLSALAP--PHGSPDPPVP 846
Score = 40.4 bits (93), Expect = 0.019
Identities = 70/240 (29%), Positives = 84/240 (35%), Gaps = 52/240 (21%)
Query: 682 PDPPARGGPSPSPPTAPKALATPAPDT--LPVEPGAPSTATASDISPGASPSLLSPWGPW 739
P PP SP P P + P + L PGAP+ AS SP L S P
Sbjct: 440 PPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQS---PS 496
Query: 740 AGSGSISSPGSTGSPL-HEEPSP-PSPQNG--------PGT--AVPAPTDFRPSATPEDL 787
G G + P PL E P PSP+ G PG A+P P P L
Sbjct: 497 EGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSL-GQPPPSPL 555
Query: 788 LASPL----------SPSEVAAVPPADPGP--------------EALHPTVPLD-LPPAT 822
L L P E PP PGP +L P P D LPP +
Sbjct: 556 LNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPS 615
Query: 823 VPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPP 882
P + + S P L L G+ + E GG + SG GD + L PP
Sbjct: 616 APPSNL---LASFLPLLA-LGPTAGDGEGSAEGAGG-----PSGEPFSGLGDLSPLLFPP 666
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 68.9 bits (167), Expect = 5e-11
Identities = 90/334 (26%), Positives = 125/334 (37%), Gaps = 68/334 (20%)
Query: 217 HFVSAFARGASAYFLFLRRDLQAQ--SRAFRAYVSRVCLRD---------QHYYSYVELP 265
HFV A G YF F ++ R + V+RVC RD +H+ S+++L
Sbjct: 225 HFVQALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLR 284
Query: 266 LACE--GGRYGLIQAAAVATSREVAHGE-VLFAAFSSAAPPTVGRPPSAAAGASGASALC 322
L C G T HG LF F++ G SA+C
Sbjct: 285 LNCSVPGDSTFYFDVLQALTGPVNLHGRSALFGVFTTQTNSIPG------------SAVC 332
Query: 323 AFPLDEVDR------LANRTRDACYT-----REGRAEDGTEVAYIEYDVNSDCAQLPVDT 371
AF LDE++R R+ D +T R G+ + S LP D
Sbjct: 333 AFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDV 392
Query: 372 LD---AYPCGSDHTPSPMASRVPLEATPILEWPG-IQLTAVAVT-MEDGH---TIAFLGD 423
L A+P P P+ P+L LT VAV M H T+ FLG
Sbjct: 393 LTFIKAHPLLDPAVP-------PVTHQPLLTLTSRALLTQVAVDGMAGPHSNITVMFLGS 445
Query: 424 SQGQLHRVYLGPGSDGHPY---------------STQSIQQGSAVSRDLTFDGTFEHLYV 468
+ G + +V G G P S + Q + L D L+V
Sbjct: 446 NDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFV 505
Query: 469 MTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGW 501
++ +P++ CA+H C SCLA +DPYCGW
Sbjct: 506 AFSGCIVYLPLSRCARHGACQRSCLASQDPYCGW 539
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 66.2 bits (160), Expect = 3e-10
Identities = 66/239 (27%), Positives = 95/239 (39%), Gaps = 28/239 (11%)
Query: 682 PDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISP-GASPSLLSPWGPWA 740
P PA P+P PT+P A P P EP +P+ A + P + ++ +P P +
Sbjct: 1013 PTSPAAAVPTPEEPTSPAAAVPP-----PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
Query: 741 GSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAV 800
+ ++ +P SP P+P P P AVP P + +P + +P P+ AA
Sbjct: 1068 PAAAVPTPEEPTSPAAAVPTPEEP-TSPAAAVPTPEE---PTSPAAAVPTPEEPASPAAA 1123
Query: 801 PPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDA 860
P P + VP PA PA P S A+ T E P A T ++
Sbjct: 1124 VPTPEEPASPAAAVPTPEEPA-FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182
Query: 861 PAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPG--LWELEEATLGASSCPCVE 917
+F+ A LE P +P TP + LEE T A+S P E
Sbjct: 1183 ASFAAVV--------ATLEEPTSPAA-------SVPTPAAMVATLEEFTSPAASVPTSE 1226
Score = 60.5 bits (145), Expect = 2e-08
Identities = 66/252 (26%), Positives = 97/252 (38%), Gaps = 36/252 (14%)
Query: 678 PLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWG 737
P P PA P+P PT+P A A P P+ P P A SP A ++ +P
Sbjct: 1035 PPEEPTSPAAAVPTPEEPTSP-AAAVPTPEE-PTSPAAAVPTPEEPTSPAA--AVPTPEE 1090
Query: 738 PWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEV 797
P + + ++ +P SP P+P P + P AVP P + P A+ +P E
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPAS-PAAAVPTPEE------PASPAAAVPTPEEP 1143
Query: 798 AAVPPADPGPE-----ALHPTVPLD--LPPATVPATTFPGAMGSVKPALDWLTREGGELP 850
A PA P PE A+ P + P A VP + +V L+ T +P
Sbjct: 1144 AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203
Query: 851 EADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGLWELEEATLGA 910
PA +TL +A + P L +++ EE T A
Sbjct: 1204 ---------TPAAMVATLEEFTSPAASVPTSEEPASLAAAVS---------NPEEPTSPA 1245
Query: 911 SSCPCVESVQGS 922
++ P +E S
Sbjct: 1246 AAVPTLEEPTSS 1257
Score = 47.8 bits (112), Expect = 1e-04
Identities = 59/236 (25%), Positives = 84/236 (35%), Gaps = 22/236 (9%)
Query: 698 PKALATPAPDT-LPVEPGAPSTATASDISPGASPSLL--SPWGPWAGSGSISSPGSTGSP 754
P+ TPA P EP + ++ P ASP+ +P P + + ++ +P SP
Sbjct: 971 PEGPVTPATTVHAPEEPDTAAVRVSTPEEP-ASPAAAVPTPEEPTSPAAAVPTPEEPTSP 1029
Query: 755 LHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHPTV 814
P P P + P AVP P + A P SP+ P P A PT
Sbjct: 1030 AAAVPPPEEPTS-PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
Query: 815 PLDLPPA---------TVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFST 865
PA T PA P PA T E P A T + PAF
Sbjct: 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT-PEEPAFPA 1147
Query: 866 STLLSGDGDSAELEGPPAP-------LILPSSLDYQYDTPGLWELEEATLGASSCP 914
+ + + ++ P P +P+ + + LEE T A+S P
Sbjct: 1148 PAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203
Score = 40.8 bits (94), Expect = 0.014
Identities = 59/229 (25%), Positives = 90/229 (39%), Gaps = 36/229 (15%)
Query: 674 SHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPST------ATASDISPG 727
S + + P P P+ + PT ++ + A EP +P+ A + +
Sbjct: 1156 SASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEF 1215
Query: 728 ASPSLLSPWG--PWAGSGSISSPGSTGSPLH-----EEPSP-------PSPQNGPGTAVP 773
SP+ P P + + ++S+P SP EEP+ P + P +VP
Sbjct: 1216 TSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVP 1275
Query: 774 APTDFRPSATPEDLLASPLSPS------EVAAVPPAD-PGPEALHPTVPLDLPPATVPAT 826
P + A L P SP+ EVAA+P A P PE VP +P A VP
Sbjct: 1276 TPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE-----VPA-IPAAAVPPM 1329
Query: 827 TFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDS 875
+G P L ++ +P ++E T A ST + D DS
Sbjct: 1330 EEVSPIG--VPFLG-VSAHTDSVPISEEGTPVLEEASSTGMWIKEDLDS 1375
Score = 37.7 bits (86), Expect = 0.12
Identities = 46/194 (23%), Positives = 70/194 (36%), Gaps = 9/194 (4%)
Query: 696 TAPKALATPAPDTLPVEPGAPSTATAS---DISPGASPSLLSP-WGPWAGSGSISSPGST 751
+AP+ PA T+ V G + A S + +P + ++ AG + +
Sbjct: 902 SAPERATVPAV-TVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI 960
Query: 752 GSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALH 811
P+ EE P P T V AP + +A P SP+ P P A
Sbjct: 961 TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
Query: 812 PTVPLDL-PPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLS 870
PT P A VP P + + P + T +P +E T +PA + T
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPTPEE 1077
Query: 871 GDGDSAELEGPPAP 884
+A + P P
Sbjct: 1078 PTSPAAAVPTPEEP 1091
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 64.3 bits (155), Expect = 1e-09
Identities = 89/364 (24%), Positives = 140/364 (38%), Gaps = 64/364 (17%)
Query: 190 WPPDPQAAFSY--EETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAY 247
W D + FS E+ AVG + + F S F Q++S A
Sbjct: 212 WLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFT------QSRSSHRVAR 265
Query: 248 VSRVCLRD--------QHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSS 299
V+RVC D + + S+++ L C Y ++ + E + +AAF+
Sbjct: 266 VARVCKGDLGGKKILQKKWTSFLKARLICHIPLYETLRGVC-SLDAETSSRTHFYAAFTL 324
Query: 300 AAPPTVGRPPSAAAGASGASALCAFPLDEVDRLAN----RTRDACYTREGRAEDGT---- 351
S ASA+C + L E+ + +D R GR E G
Sbjct: 325 ----------STQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGS-RRWGRYEGGVPEPR 373
Query: 352 -------EVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQ 404
+ Y+ + D L +D + +P + VP P+L I+
Sbjct: 374 PGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPV-------VPTRGRPLLLKRNIR 426
Query: 405 ---LTAVAVTMEDGHT--IAFLGDSQGQLHR-VYLGPGSDGHPYSTQSIQQGSAVSRDLT 458
LT VT G T + FLG + G +H+ V LG G H + + S +L
Sbjct: 427 YTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGM--HIIEETQVFRESQSVENLV 484
Query: 459 FDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGW------CVLLGRCSRRS 512
LYV S ++++P++SC+++ C C+ RDPYCGW C + RS
Sbjct: 485 ISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTIANRS 544
Query: 513 ECSR 516
+ SR
Sbjct: 545 QGSR 548
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 63.5 bits (153), Expect = 2e-09
Identities = 62/185 (33%), Positives = 71/185 (38%), Gaps = 17/185 (9%)
Query: 664 ASCDAGPMVASHQSPLVSPDPPARGGPSPS-----PPTAPKALATPAPDTLPVEPGAPST 718
AS A + P +P PPA P S PP AP TP P P P P
Sbjct: 554 ASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 613
Query: 719 ATASDISPGASP--SLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGP-GTAVPAP 775
SP + P + +SP P +G +I P PL E PSP + P GTA+P P
Sbjct: 614 GGVCISSPPSLPGGTAISPPPPLSGDATIPPP----PPLPEGVGIPSPSSLPGGTAIPPP 669
Query: 776 TDFRPSATPEDLLASPLSPSEVAAVPPADPGP-EALHPTVPLDLP--PATVPATTFPGAM 832
SA P P PP P P EA P P LP P P FPG
Sbjct: 670 PPLPGSARIPP--PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727
Query: 833 GSVKP 837
G P
Sbjct: 728 GIPPP 732
Score = 42.4 bits (98), Expect = 0.005
Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 19/119 (15%)
Query: 680 VSPDPPARGGPS-PSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGP 738
+SP PP G + P PP P+ + P+P +LP P PG S + P P
Sbjct: 630 ISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL----PG-SARIPPPPPP 684
Query: 739 WAGSGSISSP-----GSTGSPLHEEPSPPSP--------QNGPGTAVPAPTDFRPSATP 784
GS I P G G P P P P GPG P P P P
Sbjct: 685 LPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 743
Score = 38.1 bits (87), Expect = 0.093
Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 6/102 (5%)
Query: 742 SGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVA--- 798
+ +I+ P S S P+PP P + GT +P P S TP P P +
Sbjct: 558 AAAITVPPSVPSRAPVPPAPPLPGDS-GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 616
Query: 799 --AVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPA 838
+ PP+ PG A+ P PL P P +G P+
Sbjct: 617 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 658
Score = 32.3 bits (72), Expect = 5.1
Identities = 48/195 (24%), Positives = 61/195 (31%), Gaps = 9/195 (4%)
Query: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
++A++S A I+ + VP PPL PG+S G P G P P P
Sbjct: 552 EMASLSAAAITVPPSVPSRAPVPPAPPL-PGDS-----GTIIPPPPAPGDSTTPPPPPPP 605
Query: 595 EAPVLPR-GADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNW 653
P P G +S L G + LS + P SS G
Sbjct: 606 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 665
Query: 654 CVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARG--GPSPSPPTAPKALATPAPDTLPV 711
A P + + P PP G G P PP P P P P
Sbjct: 666 IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG 725
Query: 712 EPGAPSTATASDISP 726
PG P + P
Sbjct: 726 GPGIPPPPPGMGMPP 740
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 63.5 bits (153), Expect = 2e-09
Identities = 62/185 (33%), Positives = 71/185 (38%), Gaps = 17/185 (9%)
Query: 664 ASCDAGPMVASHQSPLVSPDPPARGGPSPS-----PPTAPKALATPAPDTLPVEPGAPST 718
AS A + P +P PPA P S PP AP TP P P P P
Sbjct: 563 ASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 622
Query: 719 ATASDISPGASP--SLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGP-GTAVPAP 775
SP + P + +SP P +G +I P PL E PSP + P GTA+P P
Sbjct: 623 GGVCISSPPSLPGGTAISPPPPLSGDATIPPP----PPLPEGVGIPSPSSLPGGTAIPPP 678
Query: 776 TDFRPSATPEDLLASPLSPSEVAAVPPADPGP-EALHPTVPLDLP--PATVPATTFPGAM 832
SA P P PP P P EA P P LP P P FPG
Sbjct: 679 PPLPGSARIPP--PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736
Query: 833 GSVKP 837
G P
Sbjct: 737 GIPPP 741
Score = 42.4 bits (98), Expect = 0.005
Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 19/119 (15%)
Query: 680 VSPDPPARGGPS-PSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGP 738
+SP PP G + P PP P+ + P+P +LP P PG S + P P
Sbjct: 639 ISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL----PG-SARIPPPPPP 693
Query: 739 WAGSGSISSP-----GSTGSPLHEEPSPPSP--------QNGPGTAVPAPTDFRPSATP 784
GS I P G G P P P P GPG P P P P
Sbjct: 694 LPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 752
Score = 38.1 bits (87), Expect = 0.093
Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 6/102 (5%)
Query: 742 SGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVA--- 798
+ +I+ P S S P+PP P + GT +P P S TP P P +
Sbjct: 567 AAAITVPPSVPSRAPVPPAPPLPGDS-GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 625
Query: 799 --AVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPA 838
+ PP+ PG A+ P PL P P +G P+
Sbjct: 626 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 667
Score = 32.3 bits (72), Expect = 5.1
Identities = 48/195 (24%), Positives = 61/195 (31%), Gaps = 9/195 (4%)
Query: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
++A++S A I+ + VP PPL PG+S G P G P P P
Sbjct: 561 EMASLSAAAITVPPSVPSRAPVPPAPPL-PGDS-----GTIIPPPPAPGDSTTPPPPPPP 614
Query: 595 EAPVLPR-GADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNW 653
P P G +S L G + LS + P SS G
Sbjct: 615 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 674
Query: 654 CVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARG--GPSPSPPTAPKALATPAPDTLPV 711
A P + + P PP G G P PP P P P P
Sbjct: 675 IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG 734
Query: 712 EPGAPSTATASDISP 726
PG P + P
Sbjct: 735 GPGIPPPPPGMGMPP 749
>gi|126116589 fibrocystin L [Homo sapiens]
Length = 4243
Score = 63.2 bits (152), Expect = 3e-09
Identities = 70/272 (25%), Positives = 113/272 (41%), Gaps = 21/272 (7%)
Query: 1027 GDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGT 1086
GD R + PQ V+ G +C G+ PL+ ++ P G + GT
Sbjct: 1030 GDLLRTPSQQPQVE-VYVNGIPAKC-----SGDCGFTWDSNITPLVLAISPSQGSYEEGT 1083
Query: 1087 RVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVP 1146
+TI GS + + V +VD +E + + G++G + +V
Sbjct: 1084 ILTIVGSGFSPSSAVTVSVGPVGCSLLSVDEKELKCQ----ILNGSAGHAPVAVSMADVG 1139
Query: 1147 -GRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCH 1205
+ G E F YQ H I+P G AGGT LTL+G G E+ +V+VG++ C+
Sbjct: 1140 LAQNVGGEEFYFVYQSQISH-IWPDSGSIAGGTLLTLSG----FGFNENSKVLVGNETCN 1194
Query: 1206 LLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTL--DPNITSAGPTKSF 1263
++ E ++ C T P+ T T+ ++V + R F Y P IT P
Sbjct: 1195 VI-EGDLNRITCRT-PKKTEGTVDISVTTNGFQ-ATARDAFSYNCLQTPIITDFSPKVRT 1251
Query: 1264 LSGGREICVRGQNLDVVQTPRIRVTVVSRMLQ 1295
+ G + ++G N T + V V + Q
Sbjct: 1252 ILGEVNLTIKGYNFGNELTQNMAVYVGGKTCQ 1283
Score = 56.6 bits (135), Expect = 3e-07
Identities = 48/182 (26%), Positives = 73/182 (40%), Gaps = 11/182 (6%)
Query: 1072 IHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG 1131
I ++ P G GG +T+ G+ +L V G CA+D + ++ L I
Sbjct: 2001 IQNINPSQGSFGGGQTMTVTGTGFNPQNSIIL----VCGSECAIDRLRSDYTTLLCEIPS 2056
Query: 1132 ASGEEVAGATAVEVP-GRGRGVSEHDFAYQ---DPKVHSIFPARGPRAGGTRLTLNGSKL 1187
+G A V V G+ S F Y P + ++ P RG AGGTRLT+ GS
Sbjct: 2057 NNGTGAEQACEVSVVNGKDLSQSMTPFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGSG- 2115
Query: 1188 LTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWF-GATERRLQRGQF 1246
+ +ED+ + + + C + + C T PV V G +L F
Sbjct: 2116 FSENMEDVHITIAEAKCD-VEYSNKTHIICMTDAHTLSGWAPVCVHIRGVGMAKLDNADF 2174
Query: 1247 KY 1248
Y
Sbjct: 2175 LY 2176
Score = 51.2 bits (121), Expect = 1e-05
Identities = 53/210 (25%), Positives = 88/210 (41%), Gaps = 21/210 (10%)
Query: 1072 IHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG 1131
I + P +G + GGT +T+ G ++ + ++G T C V + L IT
Sbjct: 1157 ISHIWPDSGSIAGGTLLTLSGFGFNENSKVLVGNET-----CNV------IEGDLNRITC 1205
Query: 1132 ASGEEVAGATAVEVPGRGRGVSEHD-FAY---QDPKVHSIFPARGPRAGGTRLTLNGSKL 1187
+ ++ G + V G + D F+Y Q P + P G LT+ G
Sbjct: 1206 RTPKKTEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPKVRTILGEVNLTIKGYNF 1265
Query: 1188 LTGRLEDIRVVVGDQPCHLLPEQQSEQLRC---ETSPRPTPATLPVAVWFGATERRLQRG 1244
+++ V VG + C +L ++ +RC + SP + V W A+ R
Sbjct: 1266 GNELTQNMAVYVGGKTCQILHWNFTD-IRCLLPKLSPGKHDIYVEVRNWGFASTRDKLNS 1324
Query: 1245 QFKYTLDPNITSAGPTKSFLSGGREICVRG 1274
+Y L+ +TS P + L GG EI +RG
Sbjct: 1325 SIQYVLE--VTSMFPQRGSLFGGTEITIRG 1352
Score = 49.3 bits (116), Expect = 4e-05
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 10/95 (10%)
Query: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129
PLI +V P G GGTR+T+ GS ++++DV +T+A C V EY + ++C+
Sbjct: 2091 PLITAVSPKRGSTAGGTRLTVVGSGFSENMEDV--HITIAEAKCDV---EYSNKTHIICM 2145
Query: 1130 TGASGEEVAGATAVEVPGRGRGVSE---HDFAYQD 1161
T A ++G V V RG G+++ DF Y D
Sbjct: 2146 TDA--HTLSGWAPVCVHIRGVGMAKLDNADFLYVD 2178
Score = 46.2 bits (108), Expect = 3e-04
Identities = 51/215 (23%), Positives = 86/215 (40%), Gaps = 20/215 (9%)
Query: 1067 CPAPLIHSVEP-LTG----PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYE 1121
C + S+ P +TG V G +V I G LG ++D+ + A++ E
Sbjct: 1739 CTFSYLESITPYITGVFPNSVIGSVKVLIEGEGLGTVLEDIAVFIGNQQFR-AIEVNENN 1797
Query: 1122 VSSSLVCITGASGEEVAGATAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLT 1181
+++ + + G +V V +G++ + P V S+ P G GGT L
Sbjct: 1798 ITALVTPLP-------VGHHSVSVVVGSKGLALGNLTVSSPPVASLSPTSGSIGGGTTLV 1850
Query: 1182 LNGSKLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRL 1241
+ G+ G + V +GD+PC ++ +E + C T P T + V ++
Sbjct: 1851 ITGNGFYPG---NTTVTIGDEPCQIISINPNE-VYCRT-PAGTTGMVDVKIFVNTI--AY 1903
Query: 1242 QRGQFKYTLDPNITSAGPTKSFLSGGREICVRGQN 1276
F Y L+ G S G EI + G N
Sbjct: 1904 PPLLFTYALEDTPFLRGIIPSRGPPGTEIEITGSN 1938
Score = 44.3 bits (103), Expect = 0.001
Identities = 85/367 (23%), Positives = 137/367 (37%), Gaps = 77/367 (20%)
Query: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129
P I V P G G T VTI+GS G V V + PC V + Y +++ C
Sbjct: 1659 PNIDLVLPNAGSTTGMTSVTIKGS--GFAVSSAGVKVLMGHFPCKVLSVNY---TAIECE 1713
Query: 1130 TGASGEEVAGATAV--EVPGRGRGVSEHDFAYQD---PKVHSIFPARGPRAGGTRLTLNG 1184
T + +++ + VP + +G F+Y + P + +FP G ++ + G
Sbjct: 1714 TSPAAQQLVDVDLLIHGVPAQCQG--NCTFSYLESITPYITGVFP--NSVIGSVKVLIEG 1769
Query: 1185 SKLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRG 1244
L T LEDI V +G+Q + E + +P P V+V G+ + L G
Sbjct: 1770 EGLGT-VLEDIAVFIGNQQFRAI-EVNENNITALVTPLPV-GHHSVSVVVGS--KGLALG 1824
Query: 1245 QFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRR 1304
+ P + S PT + GG + + G
Sbjct: 1825 NLTVS-SPPVASLSPTSGSIGGGTTLVITGNGF--------------------------- 1856
Query: 1305 RVVPETACSLGPSCSSQQFEEPCHVNS--SQLITCRTPALPGLPEDPWVRVEFILDNLVF 1362
T ++G +EPC + S + CRTPA V V+ ++ + +
Sbjct: 1857 -YPGNTTVTIG--------DEPCQIISINPNEVYCRTPA----GTTGMVDVKIFVNTIAY 1903
Query: 1363 DFATLNPTPFSY--EADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMI 1420
P F+Y E P L+ + +P R PG+ + G N + E+ MI
Sbjct: 1904 P-----PLLFTYALEDTPFLRGI------IPSRGPPGTEIEITGSNFGFEIL--EISVMI 1950
Query: 1421 GDGPCVV 1427
+ C V
Sbjct: 1951 NNIQCNV 1957
Score = 42.4 bits (98), Expect = 0.005
Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 42/190 (22%)
Query: 1070 PLIHSVEPLTGPVDGGTRVTIRG-------------SNLGQHVQDVLGMVTVAGVPCA-- 1114
P I S+ PL+G GT +TI+G S+ G++V+ + V + G+PC
Sbjct: 146 PTIRSITPLSGTP--GTLITIQGRIFTDVYGSNIALSSNGKNVRIL--RVYIGGMPCELL 201
Query: 1115 VDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRGRG-VSEHDFAYQDPK---------- 1163
+ + L G G V T + + ++D+ P+
Sbjct: 202 IPQSDNLYGLKLDHPNGDMGSMVCKTTGTFIGHHNVSFILDNDYGRSFPQKMAYFVSSLN 261
Query: 1164 ----------VHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQQSE 1213
V IFP++G GGT LT++G + +RV+VG +PC +L ++
Sbjct: 262 KIAMFQTYAEVTMIFPSQGSIRGGTTLTISG-RFFDQTDFPVRVLVGGEPCDILNVTEN- 319
Query: 1214 QLRCETSPRP 1223
+ C+T P+P
Sbjct: 320 SICCKTPPKP 329
Score = 40.4 bits (93), Expect = 0.019
Identities = 49/210 (23%), Positives = 83/210 (39%), Gaps = 17/210 (8%)
Query: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129
P + + P GP GT + I GSN G + ++ V + + C V V +V
Sbjct: 1916 PFLRGIIPSRGPP--GTEIEITGSNFGFEILEI--SVMINNIQCNVTMANDSVVQCIV-- 1969
Query: 1130 TGASGEEVAGATAVEVPGRGRGVSEHDFAYQDP-KVHSIFPARGPRAGGTRLTLNGSKLL 1188
G+ G V + + +G + ++ P + +I P++G GG +T+ G+
Sbjct: 1970 ----GDHAGGTFPVMMHHKTKGSAMSTVVFEYPLNIQNINPSQGSFGGGQTMTVTGTGF- 2024
Query: 1189 TGRLEDIRVVVGDQPCHLLPEQQSEQLRCE-TSPRPTPA--TLPVAVWFGA-TERRLQRG 1244
I +V G + L CE S T A V+V G + +
Sbjct: 2025 -NPQNSIILVCGSECAIDRLRSDYTTLLCEIPSNNGTGAEQACEVSVVNGKDLSQSMTPF 2083
Query: 1245 QFKYTLDPNITSAGPTKSFLSGGREICVRG 1274
+ +L P IT+ P + +GG + V G
Sbjct: 2084 TYAVSLTPLITAVSPKRGSTAGGTRLTVVG 2113
Score = 37.4 bits (85), Expect = 0.16
Identities = 43/181 (23%), Positives = 72/181 (39%), Gaps = 47/181 (25%)
Query: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLG------------MVTVAGVPCAVDA 1117
P + + P G ++G TR+TIRG Q Q G + + + C V+
Sbjct: 31 PKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAELGNSVQLISSFQSITCDVE- 89
Query: 1118 QEYEVSSSLVCITGASGEEVAGATAVEVPGRGRGVSEHDF---------------AYQDP 1162
++ S+ + C T A E+ + V V G V+E++ +++ P
Sbjct: 90 KDASHSTQITCYTRAMPED---SYTVRVSVDGVPVTENNTCKGHINSWECTFNAKSFRTP 146
Query: 1163 KVHSIFPARGPRAGGTRLTLNGSKLLTG-------------RLEDIRVVVGDQPCHLLPE 1209
+ SI P G GT +T+ G ++ T + +RV +G PC LL
Sbjct: 147 TIRSITPLSG--TPGTLITIQG-RIFTDVYGSNIALSSNGKNVRILRVYIGGMPCELLIP 203
Query: 1210 Q 1210
Q
Sbjct: 204 Q 204
Score = 36.6 bits (83), Expect = 0.27
Identities = 49/198 (24%), Positives = 76/198 (38%), Gaps = 18/198 (9%)
Query: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREA--CGEAEAVATQC-PAPLIHSVEPL 1078
C+V GD +R P+ EG VT +A + C P+I P
Sbjct: 1193 CNVIEGDLNRITCRTPKK----TEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPK 1248
Query: 1079 TGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVA 1138
+ G +TI+G N G + + V V G C + + L+ ++
Sbjct: 1249 VRTILGEVNLTIKGYNFGNELTQNMA-VYVGGKTCQILHWNFTDIRCLLPKLSPGKHDIY 1307
Query: 1139 GATAVEVPGRG----RGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLED 1194
VEV G R Y +V S+FP RG GGT +T+ G T E+
Sbjct: 1308 ----VEVRNWGFASTRDKLNSSIQYV-LEVTSMFPQRGSLFGGTEITIRGFGFSTIPAEN 1362
Query: 1195 IRVVVGDQPCHLLPEQQS 1212
V++G PC++ ++
Sbjct: 1363 -TVLLGSIPCNVTSSSEN 1379
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 62.0 bits (149), Expect = 6e-09
Identities = 80/359 (22%), Positives = 138/359 (38%), Gaps = 78/359 (21%)
Query: 217 HFVSAFARGASAYFLFLRRDLQAQS--RAFRAYVSRVCLRD---------QHYYSYVELP 265
HF+ A G YF F ++ + +A + V+R+C D +H+ S+++
Sbjct: 222 HFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKAR 281
Query: 266 LACE--GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCA 323
L C G + T +G PTV + + SA+CA
Sbjct: 282 LNCSVPGDSFFYFDVLQSITDIIQINGI-----------PTVVGVFTTQLNSIPGSAVCA 330
Query: 324 FPLDEVDRLAN----------------------RTRDACYTREGRAEDGTEVAYIEYDVN 361
F +D+++++ + R C + G AE Y +
Sbjct: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE--------AYKTS 382
Query: 362 SDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG----HT 417
D + + ++P P P+A T + +LTA++V G +T
Sbjct: 383 IDFPDETLSFIKSHPLMDSAVP-PIADEPWFTKTRVR----YRLTAISVDHSAGPYQNYT 437
Query: 418 IAFLGDSQGQLHRVYL--GPGSDGHPYSTQSIQ-----QGSAVSRD------LTFDGTFE 464
+ F+G G + +V P S + I+ + SA + + L D
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497
Query: 465 HLYVMTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQ 522
LYV S ++++P++ C ++ C SC+A RDPYCGW + G C R + +G EQ
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW-LSQGSCGRVTPGMLAEGYEQ 555
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 62.0 bits (149), Expect = 6e-09
Identities = 80/359 (22%), Positives = 138/359 (38%), Gaps = 78/359 (21%)
Query: 217 HFVSAFARGASAYFLFLRRDLQAQS--RAFRAYVSRVCLRD---------QHYYSYVELP 265
HF+ A G YF F ++ + +A + V+R+C D +H+ S+++
Sbjct: 222 HFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKAR 281
Query: 266 LACE--GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCA 323
L C G + T +G PTV + + SA+CA
Sbjct: 282 LNCSVPGDSFFYFDVLQSITDIIQINGI-----------PTVVGVFTTQLNSIPGSAVCA 330
Query: 324 FPLDEVDRLAN----------------------RTRDACYTREGRAEDGTEVAYIEYDVN 361
F +D+++++ + R C + G AE Y +
Sbjct: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE--------AYKTS 382
Query: 362 SDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG----HT 417
D + + ++P P P+A T + +LTA++V G +T
Sbjct: 383 IDFPDETLSFIKSHPLMDSAVP-PIADEPWFTKTRVR----YRLTAISVDHSAGPYQNYT 437
Query: 418 IAFLGDSQGQLHRVYL--GPGSDGHPYSTQSIQ-----QGSAVSRD------LTFDGTFE 464
+ F+G G + +V P S + I+ + SA + + L D
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497
Query: 465 HLYVMTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQ 522
LYV S ++++P++ C ++ C SC+A RDPYCGW + G C R + +G EQ
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW-LSQGSCGRVTPGMLAEGYEQ 555
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 62.0 bits (149), Expect = 6e-09
Identities = 80/359 (22%), Positives = 138/359 (38%), Gaps = 78/359 (21%)
Query: 217 HFVSAFARGASAYFLFLRRDLQAQS--RAFRAYVSRVCLRD---------QHYYSYVELP 265
HF+ A G YF F ++ + +A + V+R+C D +H+ S+++
Sbjct: 222 HFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKAR 281
Query: 266 LACE--GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCA 323
L C G + T +G PTV + + SA+CA
Sbjct: 282 LNCSVPGDSFFYFDVLQSITDIIQINGI-----------PTVVGVFTTQLNSIPGSAVCA 330
Query: 324 FPLDEVDRLAN----------------------RTRDACYTREGRAEDGTEVAYIEYDVN 361
F +D+++++ + R C + G AE Y +
Sbjct: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE--------AYKTS 382
Query: 362 SDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG----HT 417
D + + ++P P P+A T + +LTA++V G +T
Sbjct: 383 IDFPDETLSFIKSHPLMDSAVP-PIADEPWFTKTRVR----YRLTAISVDHSAGPYQNYT 437
Query: 418 IAFLGDSQGQLHRVYL--GPGSDGHPYSTQSIQ-----QGSAVSRD------LTFDGTFE 464
+ F+G G + +V P S + I+ + SA + + L D
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497
Query: 465 HLYVMTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQ 522
LYV S ++++P++ C ++ C SC+A RDPYCGW + G C R + +G EQ
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW-LSQGSCGRVTPGMLAEGYEQ 555
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 62.0 bits (149), Expect = 6e-09
Identities = 80/359 (22%), Positives = 138/359 (38%), Gaps = 78/359 (21%)
Query: 217 HFVSAFARGASAYFLFLRRDLQAQS--RAFRAYVSRVCLRD---------QHYYSYVELP 265
HF+ A G YF F ++ + +A + V+R+C D +H+ S+++
Sbjct: 222 HFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKAR 281
Query: 266 LACE--GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCA 323
L C G + T +G PTV + + SA+CA
Sbjct: 282 LNCSVPGDSFFYFDVLQSITDIIQINGI-----------PTVVGVFTTQLNSIPGSAVCA 330
Query: 324 FPLDEVDRLAN----------------------RTRDACYTREGRAEDGTEVAYIEYDVN 361
F +D+++++ + R C + G AE Y +
Sbjct: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE--------AYKTS 382
Query: 362 SDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG----HT 417
D + + ++P P P+A T + +LTA++V G +T
Sbjct: 383 IDFPDETLSFIKSHPLMDSAVP-PIADEPWFTKTRVR----YRLTAISVDHSAGPYQNYT 437
Query: 418 IAFLGDSQGQLHRVYL--GPGSDGHPYSTQSIQ-----QGSAVSRD------LTFDGTFE 464
+ F+G G + +V P S + I+ + SA + + L D
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497
Query: 465 HLYVMTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQ 522
LYV S ++++P++ C ++ C SC+A RDPYCGW + G C R + +G EQ
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW-LSQGSCGRVTPGMLAEGYEQ 555
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 62.0 bits (149), Expect = 6e-09
Identities = 55/160 (34%), Positives = 66/160 (41%), Gaps = 26/160 (16%)
Query: 676 QSPLVSPDPPARGGPSP--SPPTAPKALATP-APDTLPVE------PGAPSTATASDISP 726
Q+P PP + PSP SPP +P A +P AP+ L V PS + SP
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454
Query: 727 GASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPED 786
ASP P P A S + P PL PSPP A PSATP
Sbjct: 455 PASP----PVSPSATPPSQAPPSLAAPPLQVPPSPP-----------ASPPMSPSATPPP 499
Query: 787 LLASPLS--PSEVAAVPPADPGPEALHPTVPLDLPPATVP 824
PL+ P ++A PP P A P L PPA+ P
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539
Score = 55.8 bits (133), Expect = 4e-07
Identities = 62/190 (32%), Positives = 76/190 (40%), Gaps = 41/190 (21%)
Query: 667 DAGPMVAS-HQSPLVSPDPPARGGPSPSPPTAPKA---------LATPAP---------- 706
DA P + SPL +P P A S +PPT P LATP P
Sbjct: 291 DAAPALGPLSSSPLATPSPSA-ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349
Query: 707 --DTLPVEPGA-PSTATASDISP--GASPSLL--SPWGPWAGSGSISSPGSTGSPLHEEP 759
TLP P PS AT S SP A+ S L P P A + P PL P
Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409
Query: 760 SPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADP-----GPEALHPTV 814
SPP+ + P + + P+ P+A LL +P SP PP+ P P A P
Sbjct: 410 SPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSP------PPSPPVQAPFSPPASPPVS 461
Query: 815 PLDLPPATVP 824
P PP+ P
Sbjct: 462 PSATPPSQAP 471
Score = 52.4 bits (124), Expect = 5e-06
Identities = 58/191 (30%), Positives = 76/191 (39%), Gaps = 37/191 (19%)
Query: 665 SCDAGPMVASHQSPLVSPDPPAR---GGPS--------PSPPTAPKALATPAPDT----- 708
S A P + + SP +P A G P+ PSPP +P LATP P
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP--LATPPPQAPPALA 401
Query: 709 LPVEPGAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPP--SPQN 766
LP PS + +SP A+PS P P A + + +P PSPP +P +
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPS---PQAPNALAVHLLQ-----APFSPPPSPPVQAPFS 453
Query: 767 GPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPAT 826
P + +P+ PS P L A PL VPP+ P A P P PP P
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQ------VPPSPP---ASPPMSPSATPPPQAPPP 504
Query: 827 TFPGAMGSVKP 837
+ KP
Sbjct: 505 LAAPPLQLAKP 515
Score = 51.6 bits (122), Expect = 8e-06
Identities = 63/201 (31%), Positives = 79/201 (39%), Gaps = 37/201 (18%)
Query: 658 HLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPT-APKALATP---APDTLPVEP 713
HL S P V + SP SP PS +PP+ AP +LA P P + P P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPV----SPSATPPSQAPPSLAAPPLQVPPSPPASP 489
Query: 714 GAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVP 773
+AT P A P L +P A + P PL PSPP+ G P
Sbjct: 490 PMSPSATP---PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 546
Query: 774 -APTDFRPSATP----EDLLASPL---------SPSEVAAVPPADPGPE----------A 809
A P ATP +LA+PL SP+ A P PGP+ A
Sbjct: 547 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 606
Query: 810 LHPTVPLDLPPATVPATTFPG 830
L P P PP+ P++T G
Sbjct: 607 LAPGPP--PPPSRSPSSTLSG 625
Score = 45.8 bits (107), Expect = 4e-04
Identities = 58/191 (30%), Positives = 74/191 (38%), Gaps = 34/191 (17%)
Query: 668 AGPMVASHQSPLVSP---DPPARGGPS----PSPP-------------TAPKALATPAPD 707
A ++S +PL SP P ARG P PS P T P+ A PA
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
Query: 708 TL---PVEPGAPSTATASDISP--GASPSLLSPWGPWAGSGSISSPGSTGSP-LHEEPSP 761
L P+ +PS A S P A+P S A ++ P + P L PSP
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357
Query: 762 P-SPQNGPGTAVPAPT-----DFRPSATPEDLLASPLSPSEVAAVPP--ADPGPEALHPT 813
P +P + T++ +PT F PS L P A+PP A P P A P
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417
Query: 814 VPLDLPPATVP 824
PL P P
Sbjct: 418 SPLATPSPQAP 428
Score = 45.1 bits (105), Expect = 8e-04
Identities = 74/284 (26%), Positives = 90/284 (31%), Gaps = 80/284 (28%)
Query: 668 AGPMVASHQSPLVSPDPPARGGPSP-----------------SPPTAPKALATPAPDTLP 710
A P + SP SP P +P PP AP ALATP LP
Sbjct: 475 AAPPLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532
Query: 711 VEPG-----APSTATAS------------------------DISPGASPSLLSPWGPWAG 741
P AP + +AS SP ASP+L +P P
Sbjct: 533 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 592
Query: 742 SGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPT----DFRPSATPEDL---------- 787
S G + PP P P + + P ++TPE+L
Sbjct: 593 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 652
Query: 788 -LASPLSPSEVAAVPPA----DPGPEALH---PTVPLDLPPATVPATTFPGAMGSVKPAL 839
ASP +E+AA PA P P P PL PPAT P GS
Sbjct: 653 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP--------GSADGLC 704
Query: 840 DWLTREGGE--LPEADEWTGGDAPAFSTSTLLSGDGDSAELEGP 881
EG E P G +P S +G G A P
Sbjct: 705 TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748
Score = 39.7 bits (91), Expect = 0.032
Identities = 57/188 (30%), Positives = 73/188 (38%), Gaps = 42/188 (22%)
Query: 677 SPLVSPDPPARGGPSPSPPTAPKALAT---PAPDTLPVEPGAPSTATASDISPGASPSLL 733
+P P PP G P S +A + T PA P G + +S A+P L
Sbjct: 193 APSARPRPPTEG-PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LS 250
Query: 734 SPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQN--------------------GPGT--- 770
SP A SG S+ G+ +P H PS P P+ GP +
Sbjct: 251 SP----ARSGP-SARGTPRAPAH--PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 771 -AVPAPTDFRPSATPEDLLASPLSPSEVAAV----PPADPGPEALHPTVPLDLPPATVP- 824
A P+P+ S P L A+P S S + P A P P A L PPAT P
Sbjct: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
Query: 825 -ATTFPGA 831
ATT G+
Sbjct: 364 QATTSLGS 371
Score = 35.8 bits (81), Expect = 0.46
Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 18/128 (14%)
Query: 663 KASCDAGPMVASHQSP-LVSPDPPARGGPSPSPPTAPKAL----ATPAPDTLPV--EPGA 715
KA A + ++P L++P PP G P P PP P AL A A P+ G
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 716 PSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAP 775
AT + +P A P+ AG+ S + + E +PP+ PG P
Sbjct: 65 IGGATIPESAPRAGPTRS------AGTSSRNPASRPPASGRGERAPPAKNTSPG---PVS 115
Query: 776 TDFRPSAT 783
+ R S T
Sbjct: 116 SPGRASGT 123
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 62.0 bits (149), Expect = 6e-09
Identities = 55/160 (34%), Positives = 66/160 (41%), Gaps = 26/160 (16%)
Query: 676 QSPLVSPDPPARGGPSP--SPPTAPKALATP-APDTLPVE------PGAPSTATASDISP 726
Q+P PP + PSP SPP +P A +P AP+ L V PS + SP
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415
Query: 727 GASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPED 786
ASP P P A S + P PL PSPP A PSATP
Sbjct: 416 PASP----PVSPSATPPSQAPPSLAAPPLQVPPSPP-----------ASPPMSPSATPPP 460
Query: 787 LLASPLS--PSEVAAVPPADPGPEALHPTVPLDLPPATVP 824
PL+ P ++A PP P A P L PPA+ P
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500
Score = 55.1 bits (131), Expect = 7e-07
Identities = 58/200 (29%), Positives = 70/200 (35%), Gaps = 34/200 (17%)
Query: 667 DAGPMVAS-HQSPLVSPDPPARGGPS--------PSPPTAPKALAT-------------- 703
DA P + SPL +P P A PS PSPP P + AT
Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 341
Query: 704 -PAPDTLPVE---PGAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEP 759
P+P P+ P AP + SP P P A + S +P + L + P
Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA-TPSPQAPNALAVHLLQAP 400
Query: 760 --SPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLD 817
PPSP + PA PSATP S PS A P P A P P
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPP----SQAPPSLAAPPLQVPPSPPASPPMSPSA 456
Query: 818 LPPATVPATTFPGAMGSVKP 837
PP P + KP
Sbjct: 457 TPPPQAPPPLAAPPLQLAKP 476
Score = 51.6 bits (122), Expect = 8e-06
Identities = 63/201 (31%), Positives = 79/201 (39%), Gaps = 37/201 (18%)
Query: 658 HLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPT-APKALATP---APDTLPVEP 713
HL S P V + SP SP PS +PP+ AP +LA P P + P P
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPV----SPSATPPSQAPPSLAAPPLQVPPSPPASP 450
Query: 714 GAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVP 773
+AT P A P L +P A + P PL PSPP+ G P
Sbjct: 451 PMSPSATP---PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507
Query: 774 -APTDFRPSATP----EDLLASPL---------SPSEVAAVPPADPGPE----------A 809
A P ATP +LA+PL SP+ A P PGP+ A
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567
Query: 810 LHPTVPLDLPPATVPATTFPG 830
L P P PP+ P++T G
Sbjct: 568 LAPGPP--PPPSRSPSSTLSG 586
Score = 50.8 bits (120), Expect = 1e-05
Identities = 51/163 (31%), Positives = 65/163 (39%), Gaps = 30/163 (18%)
Query: 684 PPARGGPSPSPPTAPKALATPAP------------DTLPVEPGA-PSTATASDISP--GA 728
PP + P + LATP+P TLP P PS AT S SP A
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337
Query: 729 SPSLL--SPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPED 786
+ S L P P A + P PL PSPP+ + P + + P+ P+A
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVH 395
Query: 787 LLASPLSPSEVAAVPPADP-----GPEALHPTVPLDLPPATVP 824
LL +P SP PP+ P P A P P PP+ P
Sbjct: 396 LLQAPFSP------PPSPPVQAPFSPPASPPVSPSATPPSQAP 432
Score = 45.1 bits (105), Expect = 8e-04
Identities = 74/284 (26%), Positives = 90/284 (31%), Gaps = 80/284 (28%)
Query: 668 AGPMVASHQSPLVSPDPPARGGPSP-----------------SPPTAPKALATPAPDTLP 710
A P + SP SP P +P PP AP ALATP LP
Sbjct: 436 AAPPLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493
Query: 711 VEPG-----APSTATAS------------------------DISPGASPSLLSPWGPWAG 741
P AP + +AS SP ASP+L +P P
Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553
Query: 742 SGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPT----DFRPSATPEDL---------- 787
S G + PP P P + + P ++TPE+L
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 613
Query: 788 -LASPLSPSEVAAVPPA----DPGPEALH---PTVPLDLPPATVPATTFPGAMGSVKPAL 839
ASP +E+AA PA P P P PL PPAT P GS
Sbjct: 614 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP--------GSADGLC 665
Query: 840 DWLTREGGE--LPEADEWTGGDAPAFSTSTLLSGDGDSAELEGP 881
EG E P G +P S +G G A P
Sbjct: 666 TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709
Score = 39.7 bits (91), Expect = 0.032
Identities = 38/120 (31%), Positives = 49/120 (40%), Gaps = 14/120 (11%)
Query: 663 KASCDAGPMVASHQSP-LVSPDPPARGGPSPSPPTAPKAL----ATPAPDTLPV--EPGA 715
KA A + ++P L++P PP G P P PP P AL A A P+ G
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 716 PSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAP 775
AT + +P A P+ S P +G G + P SP SP GT P P
Sbjct: 65 IGGATIPESAPRAGPTRTSR-PPASGRGERAPPAKNTSP----GPVSSPGRASGTTRPGP 119
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,033,305
Number of Sequences: 37866
Number of extensions: 5325962
Number of successful extensions: 36765
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 1504
Number of HSP's that attempted gapping in prelim test: 21604
Number of HSP's gapped (non-prelim): 10004
length of query: 2135
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2017
effective length of database: 13,779,330
effective search space: 27792908610
effective search space used: 27792908610
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.