Guide to the Human Genome
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Search of human proteins with 40254442

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40254442 plexin B1 [Homo sapiens]
         (2135 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194272180 plexin B1 [Homo sapiens]                                4356   0.0  
gi|40254442 plexin B1 [Homo sapiens]                                 4356   0.0  
gi|253795481 plexin B3 isoform 2 [Homo sapiens]                      1264   0.0  
gi|29336063 plexin B3 isoform 1 [Homo sapiens]                       1264   0.0  
gi|149363636 plexin B2 [Homo sapiens]                                 988   0.0  
gi|49355818 plexin A1 [Homo sapiens]                                  813   0.0  
gi|157738645 plexin A4 isoform 1 [Homo sapiens]                       793   0.0  
gi|113722116 plexin A2 [Homo sapiens]                                 788   0.0  
gi|157694524 plexin D1 [Homo sapiens]                                 759   0.0  
gi|59710104 plexin A3 [Homo sapiens]                                  751   0.0  
gi|5032223 plexin C1 [Homo sapiens]                                   405   e-112
gi|157738643 plexin A4 isoform 2 [Homo sapiens]                       119   2e-26
gi|157738647 plexin A4 isoform 3 [Homo sapiens]                       119   4e-26
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]     117   2e-25
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]    105   4e-22
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s...    85   9e-16
gi|163965366 nascent polypeptide-associated complex alpha subuni...    79   4e-14
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         69   4e-11
gi|16306552 semaphorin Y [Homo sapiens]                                69   5e-11
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             66   3e-10
gi|28872814 semaphorin 4G [Homo sapiens]                               64   1e-09
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     64   2e-09
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     64   2e-09
gi|126116589 fibrocystin L [Homo sapiens]                              63   3e-09
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]           62   6e-09
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]           62   6e-09
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]           62   6e-09
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]           62   6e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    62   6e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    62   6e-09

>gi|194272180 plexin B1 [Homo sapiens]
          Length = 2135

 Score = 4356 bits (11297), Expect = 0.0
 Identities = 2135/2135 (100%), Positives = 2135/2135 (100%)

Query: 1    MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
            MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP
Sbjct: 1    MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60

Query: 61   GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 120
            GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE
Sbjct: 61   GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 120

Query: 121  QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 180
            QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
Sbjct: 121  QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 180

Query: 181  IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 240
            IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ
Sbjct: 181  IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 240

Query: 241  SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 300
            SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA
Sbjct: 241  SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 300

Query: 301  APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 360
            APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
Sbjct: 301  APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 360

Query: 361  NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 420
            NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF
Sbjct: 361  NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 420

Query: 421  LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 480
            LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA
Sbjct: 421  LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 480

Query: 481  SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
            SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
Sbjct: 481  SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540

Query: 541  PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 600
            PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP
Sbjct: 541  PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 600

Query: 601  RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 660
            RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC
Sbjct: 601  RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 660

Query: 661  THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720
            THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
Sbjct: 661  THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720

Query: 721  ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780
            ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP
Sbjct: 721  ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780

Query: 781  SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 840
            SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD
Sbjct: 781  SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 840

Query: 841  WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 900
            WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL
Sbjct: 841  WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 900

Query: 901  WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 960
            WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE
Sbjct: 901  WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 960

Query: 961  VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 1020
            VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY
Sbjct: 961  VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 1020

Query: 1021 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1080
            DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG
Sbjct: 1021 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1080

Query: 1081 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1140
            PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA
Sbjct: 1081 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1140

Query: 1141 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200
            TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG
Sbjct: 1141 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200

Query: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260
            DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT
Sbjct: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260

Query: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320
            KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS
Sbjct: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320

Query: 1321 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1380
            QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL
Sbjct: 1321 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1380

Query: 1381 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
            QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP
Sbjct: 1381 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440

Query: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
            VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL
Sbjct: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500

Query: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
            ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG
Sbjct: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560

Query: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
            SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI
Sbjct: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620

Query: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1680
            HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE
Sbjct: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1680

Query: 1681 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1740
            TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL
Sbjct: 1681 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1740

Query: 1741 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1800
            REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP
Sbjct: 1741 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1800

Query: 1801 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1860
            RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE
Sbjct: 1801 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1860

Query: 1861 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1920
            NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT
Sbjct: 1861 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1920

Query: 1921 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1980
            RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS
Sbjct: 1921 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1980

Query: 1981 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 2040
            LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR
Sbjct: 1981 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 2040

Query: 2041 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2100
            DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD
Sbjct: 2041 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2100

Query: 2101 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
            QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL
Sbjct: 2101 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135


>gi|40254442 plexin B1 [Homo sapiens]
          Length = 2135

 Score = 4356 bits (11297), Expect = 0.0
 Identities = 2135/2135 (100%), Positives = 2135/2135 (100%)

Query: 1    MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
            MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP
Sbjct: 1    MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60

Query: 61   GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 120
            GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE
Sbjct: 61   GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGALVVCGSVHQGVCE 120

Query: 121  QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 180
            QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
Sbjct: 121  QRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG 180

Query: 181  IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 240
            IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ
Sbjct: 181  IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQ 240

Query: 241  SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 300
            SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA
Sbjct: 241  SRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSSA 300

Query: 301  APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 360
            APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
Sbjct: 301  APPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV 360

Query: 361  NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 420
            NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF
Sbjct: 361  NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAF 420

Query: 421  LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 480
            LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA
Sbjct: 421  LGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVA 480

Query: 481  SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
            SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
Sbjct: 481  SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540

Query: 541  PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 600
            PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP
Sbjct: 541  PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLP 600

Query: 601  RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 660
            RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC
Sbjct: 601  RGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC 660

Query: 661  THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720
            THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
Sbjct: 661  THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720

Query: 721  ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780
            ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP
Sbjct: 721  ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRP 780

Query: 781  SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 840
            SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD
Sbjct: 781  SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALD 840

Query: 841  WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 900
            WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL
Sbjct: 841  WLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL 900

Query: 901  WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 960
            WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE
Sbjct: 901  WELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLE 960

Query: 961  VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 1020
            VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY
Sbjct: 961  VVVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLY 1020

Query: 1021 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1080
            DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG
Sbjct: 1021 DCSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTG 1080

Query: 1081 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1140
            PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA
Sbjct: 1081 PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGA 1140

Query: 1141 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200
            TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG
Sbjct: 1141 TAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200

Query: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260
            DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT
Sbjct: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260

Query: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320
            KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS
Sbjct: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320

Query: 1321 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1380
            QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL
Sbjct: 1321 QQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTL 1380

Query: 1381 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
            QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP
Sbjct: 1381 QPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440

Query: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
            VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL
Sbjct: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500

Query: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
            ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG
Sbjct: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560

Query: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
            SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI
Sbjct: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620

Query: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1680
            HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE
Sbjct: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTE 1680

Query: 1681 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1740
            TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL
Sbjct: 1681 TVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLL 1740

Query: 1741 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1800
            REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP
Sbjct: 1741 REDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDP 1800

Query: 1801 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1860
            RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE
Sbjct: 1801 RTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRE 1860

Query: 1861 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1920
            NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT
Sbjct: 1861 NQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLT 1920

Query: 1921 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1980
            RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS
Sbjct: 1921 RLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNS 1980

Query: 1981 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 2040
            LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR
Sbjct: 1981 LPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYAR 2040

Query: 2041 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2100
            DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD
Sbjct: 2041 DIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYD 2100

Query: 2101 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
            QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL
Sbjct: 2101 QIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135


>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
          Length = 1932

 Score = 1264 bits (3272), Expect = 0.0
 Identities = 690/1257 (54%), Positives = 842/1257 (66%), Gaps = 40/1257 (3%)

Query: 902  ELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEV 961
            E++    G  +CP VE + G  L+PV  E  + L  RNL  F+  P    C +EL G   
Sbjct: 693  EVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELR 752

Query: 962  VVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYD 1021
             + A +E E   D+   + CQ HQ      Q EL V +++ +    R+D+   L+V+LYD
Sbjct: 753  GLPATLE-ETAGDSGL-IHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYD 810

Query: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGP 1081
            C++GH DCS CQ A    GC+WC   +P C     C    AV   CPAP I +VEPLTGP
Sbjct: 811  CAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPG-AVELLCPAPSIDAVEPLTGP 869

Query: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
             +GG  +TI GSNLG+   DV   V+VA  PC  +   Y  S+ +VC+T  +     G  
Sbjct: 870  PEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPV 929

Query: 1142 AVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD 1201
             V +  +  G+S   F YQDP + S+ P  GP+AGGT+LT+ G  L TG   +    VG 
Sbjct: 930  RVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGG--NTSAFVGG 987

Query: 1202 QPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTK 1261
            QPC +L     E + C T P+  P    V V FG  +R L    F+YT +P + +A P+ 
Sbjct: 988  QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSA 1047

Query: 1262 SFLSGGREICVRGQNLDVVQTPRIRV------TVVSRMLQPSQGLGRRR----RVVPETA 1311
            SF  GGR I VRG  LDVVQ P + V       V +   QP     RR        P+  
Sbjct: 1048 SFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQAC 1107

Query: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTP 1371
              LG      Q    C VNSS L+ CR+PA+P        RV F LDN+  DFA+ +   
Sbjct: 1108 IQLGGGLL--QCSTVCSVNSSSLLLCRSPAVPDRAHPQ--RVFFTLDNVQVDFASASGGQ 1163

Query: 1372 -FSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTL 1430
             F Y+ +P L PL+ E P  P+R KPG V  VEGE L+L +SKEEV   IG G C+VKTL
Sbjct: 1164 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1223

Query: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESP-GAFPVAA 1489
            TR HLYCEPP   P P + +       LP+F VQMGN++ +LG VQY+ E P  AFPV A
Sbjct: 1224 TRTHLYCEPPAHAPQPANGS------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1277

Query: 1490 QVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMT 1549
            Q G+G+G ++L   V+++ LMYR KSKQALRDY+KV +QLE+LE+ V D+C+KEFTDLMT
Sbjct: 1278 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1337

Query: 1550 EMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVP--ESRRPTVEQGLGQLS 1607
            EMTDL+SDL GSGIPFLDY+ YAER FFPGH   PL      P  +    TV QGL QLS
Sbjct: 1338 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1397

Query: 1608 NLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQY 1667
            NLLNSKLFL   IHTLE Q +FS RDR +VASLL++ALHGKLEY TDI+RTLL DL A Y
Sbjct: 1398 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1457

Query: 1668 VAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVT 1727
            V +NPKLMLRRTET+VEKLLTNW+SICLY F+R+  GEPLYMLFR I++QVDKGPVD+VT
Sbjct: 1458 VHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVT 1517

Query: 1728 GKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQG------VPVKVLDCDTISQAK 1781
            GKAK TLND+RLLREDVE++PLTL  L  VGPGAG A G      VP +VLD DTI+Q K
Sbjct: 1518 GKAKRTLNDSRLLREDVEFQPLTLMVL--VGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1575

Query: 1782 EKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKV 1841
            EK+LDQ+YKG P +QRP    LD+EWRSG+AGHL LSDED+TS  Q  W+RLNTLQHYKV
Sbjct: 1576 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1635

Query: 1842 PDGATVALVPCLTKH--VLRENQDYVP-GERTPMLEDVDEGGIRPWHLVKPSDEPEPPRP 1898
            PDGATV LVP L +   + +      P GE  P LED +EGG+  WHLVK ++EPE  + 
Sbjct: 1636 PDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKV 1695

Query: 1899 RRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLL 1958
            R  SLR  E  RAKAIPEIYLTRLLSMKGTLQKFVDD FQ ILS +RP+P+AVKY FDLL
Sbjct: 1696 RCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLL 1755

Query: 1959 DEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMD 2018
            DE A++HGI D  T+HIWKTNSL LRFW+N +KNPQ +FDV+ SDN+DA+L VIAQTF+D
Sbjct: 1756 DELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFID 1815

Query: 2019 ACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNY 2078
            +CT ++HK+GRDSP+NKLLYAR+IPRYK+MVERYYADIRQ+ PAS QEMNS LAELS NY
Sbjct: 1816 SCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNY 1875

Query: 2079 SGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
            +       AL ELY +I++YYDQII+ALEED   QK+QL  RLQQ+AA VENKVTDL
Sbjct: 1876 TSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1932



 Score =  560 bits (1442), Expect = e-159
 Identities = 326/717 (45%), Positives = 417/717 (58%), Gaps = 51/717 (7%)

Query: 2   PALGPALLQALWAGWVLTLQPLPPTA---FTPNGTYLQHLARDPTSGTLYLGATNFLFQL 58
           P  G  LL  L     L+  PLP T    F+   T L HLA  P  GTLY+GA N LFQL
Sbjct: 46  PPFGLCLLLLL-----LSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQL 100

Query: 59  SPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
           SP LQLEA   TGPV+DS DC+P   P ECPQAQ T+N NQLLLVS  A  LV CG V Q
Sbjct: 101 SPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQ 160

Query: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
           GVCE RRLG + ++L + E PGD Q+VAAN P V+TVGLV   L G  LL V RG   + 
Sbjct: 161 GVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVP-LPGRDLLLVARGLAGK- 218

Query: 177 VGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRD 236
           +  G+PP+  R L    P   FS E   +L VG  S+Y++ +V AFA   SAYF+F RR 
Sbjct: 219 LSAGVPPLAIRQLAGSQP---FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRG 275

Query: 237 LQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAA 296
            +AQ+  +R+YV+RVCL D + YSYVE+PLAC+G   GLIQAA +A          L   
Sbjct: 276 ARAQAE-YRSYVARVCLGDTNLYSYVEVPLACQG--QGLIQAAFLAPG-------TLLGV 325

Query: 297 FSSAAPPTVGRPPSAAAGASGA-SALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
           F              AAG  G  +ALCAFP+ E+     + R  CYT  GR   G E A 
Sbjct: 326 F--------------AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEAT 371

Query: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
           +EY V S C  LP+D+ ++YPCG +HTPSP+A R PLE  P+L+  G  ++AVA    DG
Sbjct: 372 VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKL-GQPVSAVAALQADG 430

Query: 416 HTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTL 474
           H IAFLGD+QGQL++V+L  GS G  Y +Q +   GSA+S DL  D +  HLYV+T   +
Sbjct: 431 HMIAFLGDTQGQLYKVFLH-GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQV 489

Query: 475 LKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCL 534
            ++PVA+C Q  DCASCL  +DP CGWCVL GRC+R+ +C R     QWLWS++ +  CL
Sbjct: 490 DRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCL 549

Query: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
            + ++ P +  R+E  +V LSVP LP L   E + C FG++ S A + G  V C +P   
Sbjct: 550 HIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQD 609

Query: 595 EAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWC 654
           + P+ P G D+V+V + L F  V +A T+ SFYDC AV  L  +A C+ACV S W C+WC
Sbjct: 610 QVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWC 669

Query: 655 VWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPV 711
                C +   C  G         +   D   RG     P   P+      P  +PV
Sbjct: 670 PQSSHCVYGEHCPEGERTIYSAQEV---DIQVRG-----PGACPQVEGLAGPHLVPV 718


>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
          Length = 1909

 Score = 1264 bits (3272), Expect = 0.0
 Identities = 690/1257 (54%), Positives = 842/1257 (66%), Gaps = 40/1257 (3%)

Query: 902  ELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEV 961
            E++    G  +CP VE + G  L+PV  E  + L  RNL  F+  P    C +EL G   
Sbjct: 670  EVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELR 729

Query: 962  VVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYD 1021
             + A +E E   D+   + CQ HQ      Q EL V +++ +    R+D+   L+V+LYD
Sbjct: 730  GLPATLE-ETAGDSGL-IHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYD 787

Query: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGP 1081
            C++GH DCS CQ A    GC+WC   +P C     C    AV   CPAP I +VEPLTGP
Sbjct: 788  CAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPG-AVELLCPAPSIDAVEPLTGP 846

Query: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
             +GG  +TI GSNLG+   DV   V+VA  PC  +   Y  S+ +VC+T  +     G  
Sbjct: 847  PEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPV 906

Query: 1142 AVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD 1201
             V +  +  G+S   F YQDP + S+ P  GP+AGGT+LT+ G  L TG   +    VG 
Sbjct: 907  RVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGG--NTSAFVGG 964

Query: 1202 QPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTK 1261
            QPC +L     E + C T P+  P    V V FG  +R L    F+YT +P + +A P+ 
Sbjct: 965  QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSA 1024

Query: 1262 SFLSGGREICVRGQNLDVVQTPRIRV------TVVSRMLQPSQGLGRRR----RVVPETA 1311
            SF  GGR I VRG  LDVVQ P + V       V +   QP     RR        P+  
Sbjct: 1025 SFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQAC 1084

Query: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTP 1371
              LG      Q    C VNSS L+ CR+PA+P        RV F LDN+  DFA+ +   
Sbjct: 1085 IQLGGGLL--QCSTVCSVNSSSLLLCRSPAVPDRAHPQ--RVFFTLDNVQVDFASASGGQ 1140

Query: 1372 -FSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTL 1430
             F Y+ +P L PL+ E P  P+R KPG V  VEGE L+L +SKEEV   IG G C+VKTL
Sbjct: 1141 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1200

Query: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESP-GAFPVAA 1489
            TR HLYCEPP   P P + +       LP+F VQMGN++ +LG VQY+ E P  AFPV A
Sbjct: 1201 TRTHLYCEPPAHAPQPANGS------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1254

Query: 1490 QVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMT 1549
            Q G+G+G ++L   V+++ LMYR KSKQALRDY+KV +QLE+LE+ V D+C+KEFTDLMT
Sbjct: 1255 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1314

Query: 1550 EMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVP--ESRRPTVEQGLGQLS 1607
            EMTDL+SDL GSGIPFLDY+ YAER FFPGH   PL      P  +    TV QGL QLS
Sbjct: 1315 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1374

Query: 1608 NLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQY 1667
            NLLNSKLFL   IHTLE Q +FS RDR +VASLL++ALHGKLEY TDI+RTLL DL A Y
Sbjct: 1375 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1434

Query: 1668 VAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVT 1727
            V +NPKLMLRRTET+VEKLLTNW+SICLY F+R+  GEPLYMLFR I++QVDKGPVD+VT
Sbjct: 1435 VHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVT 1494

Query: 1728 GKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQG------VPVKVLDCDTISQAK 1781
            GKAK TLND+RLLREDVE++PLTL  L  VGPGAG A G      VP +VLD DTI+Q K
Sbjct: 1495 GKAKRTLNDSRLLREDVEFQPLTLMVL--VGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1552

Query: 1782 EKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKV 1841
            EK+LDQ+YKG P +QRP    LD+EWRSG+AGHL LSDED+TS  Q  W+RLNTLQHYKV
Sbjct: 1553 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1612

Query: 1842 PDGATVALVPCLTKH--VLRENQDYVP-GERTPMLEDVDEGGIRPWHLVKPSDEPEPPRP 1898
            PDGATV LVP L +   + +      P GE  P LED +EGG+  WHLVK ++EPE  + 
Sbjct: 1613 PDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKV 1672

Query: 1899 RRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLL 1958
            R  SLR  E  RAKAIPEIYLTRLLSMKGTLQKFVDD FQ ILS +RP+P+AVKY FDLL
Sbjct: 1673 RCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLL 1732

Query: 1959 DEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMD 2018
            DE A++HGI D  T+HIWKTNSL LRFW+N +KNPQ +FDV+ SDN+DA+L VIAQTF+D
Sbjct: 1733 DELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFID 1792

Query: 2019 ACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNY 2078
            +CT ++HK+GRDSP+NKLLYAR+IPRYK+MVERYYADIRQ+ PAS QEMNS LAELS NY
Sbjct: 1793 SCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNY 1852

Query: 2079 SGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
            +       AL ELY +I++YYDQII+ALEED   QK+QL  RLQQ+AA VENKVTDL
Sbjct: 1853 TSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909



 Score =  560 bits (1442), Expect = e-159
 Identities = 326/717 (45%), Positives = 417/717 (58%), Gaps = 51/717 (7%)

Query: 2   PALGPALLQALWAGWVLTLQPLPPTA---FTPNGTYLQHLARDPTSGTLYLGATNFLFQL 58
           P  G  LL  L     L+  PLP T    F+   T L HLA  P  GTLY+GA N LFQL
Sbjct: 23  PPFGLCLLLLL-----LSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQL 77

Query: 59  SPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
           SP LQLEA   TGPV+DS DC+P   P ECPQAQ T+N NQLLLVS  A  LV CG V Q
Sbjct: 78  SPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQ 137

Query: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
           GVCE RRLG + ++L + E PGD Q+VAAN P V+TVGLV   L G  LL V RG   + 
Sbjct: 138 GVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVP-LPGRDLLLVARGLAGK- 195

Query: 177 VGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRD 236
           +  G+PP+  R L    P   FS E   +L VG  S+Y++ +V AFA   SAYF+F RR 
Sbjct: 196 LSAGVPPLAIRQLAGSQP---FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRG 252

Query: 237 LQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAA 296
            +AQ+  +R+YV+RVCL D + YSYVE+PLAC+G   GLIQAA +A          L   
Sbjct: 253 ARAQAE-YRSYVARVCLGDTNLYSYVEVPLACQG--QGLIQAAFLAPG-------TLLGV 302

Query: 297 FSSAAPPTVGRPPSAAAGASGA-SALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
           F              AAG  G  +ALCAFP+ E+     + R  CYT  GR   G E A 
Sbjct: 303 F--------------AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEAT 348

Query: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
           +EY V S C  LP+D+ ++YPCG +HTPSP+A R PLE  P+L+  G  ++AVA    DG
Sbjct: 349 VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKL-GQPVSAVAALQADG 407

Query: 416 HTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTL 474
           H IAFLGD+QGQL++V+L  GS G  Y +Q +   GSA+S DL  D +  HLYV+T   +
Sbjct: 408 HMIAFLGDTQGQLYKVFLH-GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQV 466

Query: 475 LKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCL 534
            ++PVA+C Q  DCASCL  +DP CGWCVL GRC+R+ +C R     QWLWS++ +  CL
Sbjct: 467 DRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCL 526

Query: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
            + ++ P +  R+E  +V LSVP LP L   E + C FG++ S A + G  V C +P   
Sbjct: 527 HIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQD 586

Query: 595 EAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWC 654
           + P+ P G D+V+V + L F  V +A T+ SFYDC AV  L  +A C+ACV S W C+WC
Sbjct: 587 QVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWC 646

Query: 655 VWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPV 711
                C +   C  G         +   D   RG     P   P+      P  +PV
Sbjct: 647 PQSSHCVYGEHCPEGERTIYSAQEV---DIQVRG-----PGACPQVEGLAGPHLVPV 695


>gi|149363636 plexin B2 [Homo sapiens]
          Length = 1838

 Score =  988 bits (2553), Expect = 0.0
 Identities = 555/1161 (47%), Positives = 740/1161 (63%), Gaps = 59/1161 (5%)

Query: 985  QLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQYGCVWC 1044
            +LS++A +  L + L+++  G+  +DS   LHV LY+CS G  DCS C+ A P Y C WC
Sbjct: 727  KLSHDANET-LPLHLYVKSYGK-NIDSK--LHVTLYNCSFGRSDCSLCRAANPDYRCAWC 782

Query: 1045 EGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLG 1104
             G+  RCV    C       ++CP P+I  ++P TGP+ GG R+TI GSNLG    D+  
Sbjct: 783  GGQS-RCVYEALCN----TTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQ- 836

Query: 1105 MVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGR-GRGVSEHDFAYQDPK 1163
             ++VAG  C+   + Y VS+ +VC+  A+     G   V+V G+ GR      F +Q PK
Sbjct: 837  RISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPK 896

Query: 1164 VHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRP 1223
              S+ P +GP+AGGT LT++G+ L TG  ED+RV +   PC +   +   QL+C T P+ 
Sbjct: 897  PLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVT--KFGAQLQCVTGPQA 954

Query: 1224 TPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTP 1283
            T   + + V +G +        F Y  +P + +  P +SF SGGR I V GQ   ++Q  
Sbjct: 955  TRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQ-- 1012

Query: 1284 RIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEPCHVNSSQLITCRTPALP 1343
            R  + V++  LQ  Q       + P T              +    N ++++   +PA+P
Sbjct: 1013 RFAMVVIAEPLQSWQPPREAESLQPMTVVGT----------DYVFHNDTKVVFL-SPAVP 1061

Query: 1344 GLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVE 1403
              PE   + V   +D       T     F Y  DPT      E+ T   + +   +    
Sbjct: 1062 EEPEAYNLTVLIEMDGHRALLRT-EAGAFEYVPDPTF-----ENFTGGVKKQVNKLIHAR 1115

Query: 1404 GENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTV 1463
            G NL+ AM+ +E  A +G   C +KTLT   LYCEPP  QP P+    R+   +LPEF V
Sbjct: 1116 GTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIV 1175

Query: 1464 QMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLM----YRRKSKQAL 1519
            + G+  + LG V+YD          + V L +   L+ + +++++ +    Y RKS+QA 
Sbjct: 1176 KFGSREWVLGRVEYDTR-------VSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAE 1228

Query: 1520 RDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFF-- 1577
            R+Y+K++ QLE LE SVRDRCKKEFTDLM EM D T+D+  +GIP LDYK Y +R+FF  
Sbjct: 1229 REYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLP 1288

Query: 1578 --PGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRA 1635
               G ++  +   L +PE RRP VEQ L Q SNLLNSK FL  FIHTLE+QR FSAR + 
Sbjct: 1289 SKDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKV 1348

Query: 1636 YVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKNPKLMLRRTETVVEKLLTNWMSIC 1694
            Y ASLLTVALHGKLEY+TDI+ TL  +L+ QYV AKNPKLMLRR+ETVVE++L+NWMSIC
Sbjct: 1349 YFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERMLSNWMSIC 1408

Query: 1695 LYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNAL 1754
            LY +++DS GEPLY LF+ IKHQV+KGPVD+V  KAKYTLND  LL +DVEY PLT++ +
Sbjct: 1409 LYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVI 1468

Query: 1755 LAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGH 1814
            +           +PVKVL+CDTISQ KEK++DQ+Y+G P +  P P ++ +EWR G    
Sbjct: 1469 VQ----DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQ 1524

Query: 1815 LILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLE 1874
             ILSD D+TS+ +G W+R+NTL HY V DGAT+ L          ++Q  +PGER  +LE
Sbjct: 1525 -ILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKVGVSQQPEDSQQDLPGERHALLE 1583

Query: 1875 DVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVD 1934
            + +    R WHLV+P+DE +  + +RGS++  E+ER KAI EIYLTRLLS+KGTLQ+FVD
Sbjct: 1584 EEN----RVWHLVRPTDEVDEGKSKRGSVK--EKERTKAITEIYLTRLLSVKGTLQQFVD 1637

Query: 1935 DLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQ 1994
            + FQ +L+    VP AVKYFFD LDEQA++H I D+DTIHIWKTNSLPLRFW+NI+KNP 
Sbjct: 1638 NFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVNILKNPH 1697

Query: 1995 FVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYA 2054
            F+FDV   + +DA L VIAQTFMDACT  +HKL RDSP NKLLYA++I  YK+MVE YY 
Sbjct: 1698 FIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVEDYYK 1757

Query: 2055 DIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQK 2114
             IRQ V  SDQ+MN+ LAE+S  ++  L   VALH+LY+Y  KYYD+II ALEED  AQK
Sbjct: 1758 GIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDPAAQK 1817

Query: 2115 MQLGYRLQQIAAAVENKVTDL 2135
            MQL +RLQQIAAA+ENKVTDL
Sbjct: 1818 MQLAFRLQQIAAALENKVTDL 1838



 Score =  417 bits (1072), Expect = e-116
 Identities = 251/670 (37%), Positives = 350/670 (52%), Gaps = 41/670 (6%)

Query: 35  LQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPT 94
           L HLA D  SG +YLGA N L+QL   LQLE  V+TGP LD++ C PP+   +C +A+ T
Sbjct: 34  LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMT 93

Query: 95  NNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVST 152
           +N NQLLL+ P    LV CGS+ +G+C  R L  +   L   +  G+  +VA+ND  V+T
Sbjct: 94  DNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVAT 153

Query: 153 VGLVAQ-GLAGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQAAF-SYEETAKLAVGR 210
           VGLV+  G  G+ +LFVG+G      G     ++TR L   D + AF +Y + A    G 
Sbjct: 154 VGLVSSTGPGGDRVLFVGKGNGPHDNG---IIVSTRLLDRTDSREAFEAYTDHATYKAGY 210

Query: 211 LSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACE- 269
           LS  +  FV+AF  G   +F+F ++D        R  ++R+C  D +YYSY+E+ L C  
Sbjct: 211 LSTNTQQFVAAFEDGPYVFFVFNQQDKHPARN--RTLLARMCREDPNYYSYLEMDLQCRD 268

Query: 270 ----GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFP 325
                  +G   AA+VA       G VL+A FS           S ++G  GA  LC FP
Sbjct: 269 PDIHAAAFGTCLAASVAAP---GSGRVLYAVFSR---------DSRSSGGPGAG-LCLFP 315

Query: 326 LDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSP 385
           LD+V       R+ACYT    A D   + Y  +  +  C      +  ++PCGS+H P P
Sbjct: 316 LDKVHAKMEANRNACYTGTREARD---IFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYP 372

Query: 386 MASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQ 445
           + SR  L  T +L+  G+ LTAV V  E+ HT+AFLG S G++ +VYL P      Y + 
Sbjct: 373 LGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSI 432

Query: 446 SIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLL 505
            ++    V RDL   G    LY MTQ  + ++PV  C  +  C  C   +DPYCGWCV+ 
Sbjct: 433 LVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVE 492

Query: 506 GRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPG 565
           GRC+R++EC R +    WLWS      C+ V +  P N+SR    EV L+V  LP L   
Sbjct: 493 GRCTRKAECPRAEEASHWLWS--RSKSCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEE 550

Query: 566 ESYSCHFGEH-QSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVE--LRFGAVVIAKT 622
           +   C FGE    PA + G  V+C S  PS  PV P G D+V+V+++  LR G + +   
Sbjct: 551 DELLCLFGESPPHPARVEGEAVICNS--PSSIPVTPPGQDHVAVTIQLLLRRGNIFLTSY 608

Query: 623 SLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSP 682
              FYDC     L  +  C +CVS+RW C W +  H C   +      +V +H    +  
Sbjct: 609 QYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRAH----MED 664

Query: 683 DPPARGGPSP 692
             P   GPSP
Sbjct: 665 SCPQFLGPSP 674



 Score = 34.7 bits (78), Expect = 1.0
 Identities = 48/215 (22%), Positives = 75/215 (34%), Gaps = 33/215 (15%)

Query: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS 540
           S  ++L C SC+++R   C W +    C   S       PE  +     E  C Q    S
Sbjct: 620 SLEENLPCISCVSNRWT-CQWDLRYHECREASP-----NPEDGIVRAHMEDSCPQFLGPS 673

Query: 541 PANISREETREVFLSVPDLPPLWPGESYSCHFG----EHQSPALLTGSGVMC---PSPDP 593
           P  I      +V     +L  +   +  S H G    +   P  +  SG      P    
Sbjct: 674 PLVIPMNHETDVNFQGKNLDTV---KGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSH 730

Query: 594 SEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSR--WGC 651
                LP    YV       +G  + +K  ++ Y+C         + C  C ++   + C
Sbjct: 731 DANETLPLHL-YVK-----SYGKNIDSKLHVTLYNCSF-----GRSDCSLCRAANPDYRC 779

Query: 652 NWCVWQHLCTHKASC----DAGPMVASHQSPLVSP 682
            WC  Q  C ++A C    +  P V +   P   P
Sbjct: 780 AWCGGQSRCVYEALCNTTSECPPPVITRIQPETGP 814


>gi|49355818 plexin A1 [Homo sapiens]
          Length = 1873

 Score =  813 bits (2100), Expect = 0.0
 Identities = 501/1248 (40%), Positives = 685/1248 (54%), Gaps = 124/1248 (9%)

Query: 925  MPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPPPDTQCHVTCQQH 984
            +PV V + I L  RNL   Q G    EC+  + G    V A             + CQ  
Sbjct: 694  VPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTAL------RFNSSSLQCQNS 747

Query: 985  QLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQYGCVW 1043
              SYE     +L V L +   G   +D+ + +   LY C      C  C  A P++ C W
Sbjct: 748  SYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGW 807

Query: 1044 CEGERPRCVTREACG--------EAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNL 1095
            C  ER RC  R  C          A   +++C  P I  + P TGP  GGTR+TI G NL
Sbjct: 808  CVAER-RCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENL 866

Query: 1096 GQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRG-----R 1150
            G   +DV   V V  V C+    EY  +  +VC  G +    A    VEV  R      R
Sbjct: 867  GLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYR 926

Query: 1151 GVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQ 1210
             +S   F +  P  + + P+RGP +GGT + + GS L  G   D+ V VG +PC     +
Sbjct: 927  ALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAG--SDVAVSVGGRPCSF-SWR 983

Query: 1211 QSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREI 1270
             S ++RC T P  +P + P+ +     +      ++ YT DP I    P  S  SGG  +
Sbjct: 984  NSREIRCLTPPGQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLL 1043

Query: 1271 CVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEPCHVN 1330
             V G NL  V+ PRIR            G+ R                     E  C V 
Sbjct: 1044 TVTGTNLATVREPRIRAKY--------GGIER---------------------ENGCLVY 1074

Query: 1331 SSQLITCRTPAL-------PGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPL 1383
            +   + CR P++       P L E P   + F++DN V     LN T F Y  DP L+PL
Sbjct: 1075 NDTTMVCRAPSVANPVRSPPELGERP-DELGFVMDN-VRSLLVLNSTSFLYYPDPVLEPL 1132

Query: 1384 NPEDPTMPFRHKPGSVFSVEGENL---DLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
            +P   T     KP S   ++G NL       S+     +IG  PC + T++   L CE P
Sbjct: 1133 SP---TGLLELKPSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAP 1188

Query: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
                L   H +          TV+ G   FS G +Q   +S    P  A VG+G G  LL
Sbjct: 1189 ---NLTGQHKV----------TVRAGGFEFSPGTLQVYSDSLLTLP--AIVGIGGGGGLL 1233

Query: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
             L ++ +++ Y+RKS+ A R  K++Q+Q++NLES V   CK+ F +L T++ +LT+DL G
Sbjct: 1234 LLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDG 1293

Query: 1561 SGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFI 1620
            +GIPFLDY+ YA R+ FPG  + P+ +++ V    +  VE+ L     LL  K FL  FI
Sbjct: 1294 AGIPFLDYRTYAMRVLFPGIEDHPVLKEMEV----QANVEKSLTLFGQLLTKKHFLLTFI 1349

Query: 1621 HTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKN-PKLMLRR 1678
             TLE+QR+FS RDR  VASL+  AL G++EY T +L+ LLSDL+ + + +KN PKL+LRR
Sbjct: 1350 RTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRR 1409

Query: 1679 TETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNR 1738
            TE+V EK+LTNW +  LY F+++  GEPL+ML+  IK Q++KGP+D++TG+A+Y+L++++
Sbjct: 1410 TESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDK 1469

Query: 1739 LLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYKGVPLTQRP 1798
            L+R+ ++Y+ LTLN    V P    A  VPVK LDCDT++QAKEK+LD  YKGVP +QRP
Sbjct: 1470 LIRQQIDYKTLTLNC---VNPENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRP 1526

Query: 1799 DPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVL 1858
                +D+EWR G    +IL DEDVT+++   W+RLNTL HY+V DG++VALVP  T    
Sbjct: 1527 KAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYN 1586

Query: 1859 RENQDYVPGE-------------------RTPMLEDVDEGGIRPWHLVKPSDEPEPPRPR 1899
              N                          RTPM+    E G + WHLVK  D  +     
Sbjct: 1587 ISNSSTFTKSLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDHLDQREGD 1646

Query: 1900 RGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR---PVPLAVKYFFD 1956
            RGS         K + EIYLTRLL+ KGTLQKFVDDLF+ I ST+     +PLA+KY FD
Sbjct: 1647 RGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFD 1697

Query: 1957 LLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTF 2016
             LDEQA +H I D D  H WK+N LPLRFW+N+IKNPQFVFD+  +   DA L V+AQTF
Sbjct: 1698 FLDEQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTF 1757

Query: 2017 MDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSW 2076
            MD+C+ ++HKLG+DSP NKLLYA+DIP YK  VERYYADI +    SDQ+M++ LAE S 
Sbjct: 1758 MDSCSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSR 1817

Query: 2077 NYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQI 2124
             +     +  ALHE+Y YI KY D+I+ ALE+D  A++ +L  +L+Q+
Sbjct: 1818 LHLSQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQV 1865



 Score =  256 bits (653), Expect = 2e-67
 Identities = 218/751 (29%), Positives = 332/751 (44%), Gaps = 86/751 (11%)

Query: 24  PPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPV 83
           P   F+ +   L HL     +G +Y+GA N +++LS  L L     TGPV D+  C PP 
Sbjct: 17  PFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPP 76

Query: 84  MPDECPQAQ-PTNNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDT 140
               CP     T+N N+LLL+   A  L+ CGS  QG+C+  RL  L +L     R    
Sbjct: 77  SVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRK--E 134

Query: 141 QYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALWPPDPQA---A 197
            Y+++   A S  G++  G  G+    +  G    G     P +++R L   +  A    
Sbjct: 135 HYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFG 194

Query: 198 FSYEET-----AKLAVGRLSEYSH---HFVSAFARGASAYFLFLRRDLQAQS------RA 243
           F Y++       K+    LS++     ++V +F      Y+L L+ D Q  S        
Sbjct: 195 FVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHF 254

Query: 244 FRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQAAAVAT-SREVAHG-------EVL 293
           F + + R+C+ D  +YSYVE P+ CE  G  Y L+Q A ++   R +AH        +VL
Sbjct: 255 FTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVL 314

Query: 294 FAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEV 353
           F  F+      V +PP         SALC F L  +         +CY  EG+       
Sbjct: 315 FTVFAQGQKNRV-KPPKE-------SALCLFTLRAIKEKIKERIQSCYRGEGKLS----- 361

Query: 354 AYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVT 411
             + + +N +  C   P+   D + CG D    P+   V +E TP+       LTAVA  
Sbjct: 362 --LPWLLNKELGCINSPLQIDDDF-CGQDFN-QPLGGTVTIEGTPLFVDKDDGLTAVAAY 417

Query: 412 MEDGHTIAFLGDSQGQLHRVYL---GPGSDGHP---YSTQSIQQGSAVSRDLTFDGTFEH 465
              G T+ F G   G++ ++ +    PG  G P   Y +   Q+GS + RDL      ++
Sbjct: 418 DYRGRTVVFAGTRSGRIRKILVDLSNPG--GRPALAYESVVAQEGSPILRDLVLSPNHQY 475

Query: 466 LYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLW 525
           LY MT+  + +VPV SC Q+  C  CL  RDP+CGWCVL   CSRR  C R   P+++  
Sbjct: 476 LYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAA 535

Query: 526 SFQPELGCLQVAAMSPANISREETR-EVFLSVPDLPPLWPGESYSCHFGEH-QSPALLTG 583
                L C+Q+  + P N+S   ++  + L   ++P L  G   +C F +  +S ++L  
Sbjct: 536 DL---LQCVQL-TVQPRNVSVTMSQVPLVLQAWNVPDLSAG--VNCSFEDFTESESVLED 589

Query: 584 SGVMCPSPDPSEAPVLPRGAD---YVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQ 640
             + C SP   E   + RG      V + ++ +      A     FY+C           
Sbjct: 590 GRIHCRSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSV------HQS 643

Query: 641 CQACVSSRWGCNWCVWQHLCTHK-ASCD--AGPMVASHQSPLVSPDPPARGGPSPSPPTA 697
           C +CV+  + C+WC ++H+CTH  A C    G +  S   P + P            P  
Sbjct: 644 CLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPVGVVKPIT 703

Query: 698 PKALATPAP-------DTLPVEPGAPSTATA 721
             A   P P       + L   PG+P+  TA
Sbjct: 704 LAARNLPQPQSGQRGYECLFHIPGSPARVTA 734



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 63/255 (24%), Positives = 94/255 (36%), Gaps = 36/255 (14%)

Query: 481 SCAQHLDCASCLAHRDPYCGWCVLLGRCSRR-SECSRGQGPEQWLWSFQPELGCLQVAAM 539
           +C+ H  C SC+    P C WC     C+   ++C+  +G             C Q+   
Sbjct: 637 NCSVHQSCLSCVNGSFP-CHWCKYRHVCTHNVADCAFLEG------RVNVSEDCPQILPS 689

Query: 540 SPANISREETREVFLSVPDLPPLWPGE-SYSCHFGEHQSPALLTGSGVMCPSPDPSEAPV 598
           +   +     + + L+  +LP    G+  Y C F    SPA +T       S     +  
Sbjct: 690 TQIYVPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTALRFNSSSLQCQNSSY 749

Query: 599 LPRGADYVSVSVELRF---GAVVI---AKTSLSFYDCVAVTELRPSAQCQACVSS--RWG 650
              G D   + V L     G  VI          Y C A+ E      C  C+ +  R+ 
Sbjct: 750 SYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRE-----SCGLCLKADPRFE 804

Query: 651 CNWCVWQHLCTHKASCDAG-PMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTL 709
           C WCV +  C+ +  C A  P    H          AR G S    T PK L   +P+T 
Sbjct: 805 CGWCVAERRCSLRHHCAADTPASWMH----------ARHGSSRC--TDPKILKL-SPETG 851

Query: 710 PVEPGAPSTATASDI 724
           P + G   T T  ++
Sbjct: 852 PRQGGTRLTITGENL 866



 Score = 33.5 bits (75), Expect = 2.3
 Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 10/81 (12%)

Query: 471 QSTLLKVPVASCAQHLDCASCLAHRDPY--CGWCVLLGRCSRRSECSRGQGPEQWLWSFQ 528
           Q+ L K P    A    C  CL   DP   CGWCV   RCS R  C+    P  W+ +  
Sbjct: 780 QAHLYKCP----ALRESCGLCLK-ADPRFECGWCVAERRCSLRHHCA-ADTPASWMHARH 833

Query: 529 PELGCL--QVAAMSPANISRE 547
               C   ++  +SP    R+
Sbjct: 834 GSSRCTDPKILKLSPETGPRQ 854


>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
          Length = 1894

 Score =  793 bits (2047), Expect = 0.0
 Identities = 482/1259 (38%), Positives = 694/1259 (55%), Gaps = 120/1259 (9%)

Query: 913  CPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPP 972
            CP +  V    L+PV V + I L  +NL   Q G    EC++ ++G E  V A       
Sbjct: 701  CPQLLRVD-KILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPAL------ 753

Query: 973  PDTQCHVTCQQHQLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSR 1031
                  V CQ    SYE ++   L V L +   G   +D+     V LY C      C  
Sbjct: 754  RFNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGL 813

Query: 1032 CQTAMPQYGCVWCEGERPRCVTREACGEAEA-------VATQCPAPLIHSVEPLTGPVDG 1084
            C  A P + C WC+G   +C  R+ C   E+         ++C  P I  + P+TGP +G
Sbjct: 814  CLKADPDFACGWCQGPG-QCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREG 872

Query: 1085 GTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG-ASGEEVAGATAV 1143
            GT+VTIRG NLG   +D+   V VAGV C+     Y  +  +VC  G A   + AG   +
Sbjct: 873  GTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEI 932

Query: 1144 EVP---GRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200
             V          S   + +    +  + P+RGP +GGT++T+ G+ L  G   ++ V+ G
Sbjct: 933  CVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAG--SNVVVMFG 990

Query: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260
             QPC L   +    + C T+       + V+V     +   Q   F+Y  DP I    P 
Sbjct: 991  KQPC-LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIH-QDLVFQYVEDPTIVRIEPE 1048

Query: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320
             S +SG   I V G +LD++Q P+IR                                  
Sbjct: 1049 WSIVSGNTPIAVWGTHLDLIQNPQIRA-----------------------------KHGG 1079

Query: 1321 QQFEEPCHVNSSQLITCRTPAL---PGLPEDPWVRVE---FILDNLVFDFATLNPTPFSY 1374
            ++    C V ++  +TC+ PAL   P    D   R E   FILDN V     LN T F+Y
Sbjct: 1080 KEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDN-VQSLLILNKTNFTY 1138

Query: 1375 EADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMS----KEEVVAMIGDGPCVVKTL 1430
              +P  +   P         KPG+   ++G+NL   ++    K     ++G+ PC V T+
Sbjct: 1139 YPNPVFEAFGPSGI---LELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPCTV-TV 1194

Query: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQ 1490
            +   L CE P    + RH  +            ++G + +S G V    +SP + P  A 
Sbjct: 1195 SDVQLLCESP--NLIGRHKVM-----------ARVGGMEYSPGMVYIAPDSPLSLP--AI 1239

Query: 1491 VGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTE 1550
            V + V   LL + ++ +++ Y+RKS+++    K++Q+Q++NLES V   CK+ F +L T+
Sbjct: 1240 VSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTD 1299

Query: 1551 MTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLL 1610
            + +LTSDL G+GIPFLDY+ Y  R+ FPG  + P+ RDL VP  R+  VE+GL   + L+
Sbjct: 1300 IHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLI 1359

Query: 1611 NSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-A 1669
            N+K+FL  FI TLESQR+FS RDR  VASL+   L  KLEY TD+L+ LL+DL+ + + +
Sbjct: 1360 NNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLES 1419

Query: 1670 KN-PKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTG 1728
            KN PKL+LRRTE+V EK+LTNW +  LY F+++  GEPL+ LF  IK Q++KGP+D++TG
Sbjct: 1420 KNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITG 1479

Query: 1729 KAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQL 1788
            +A+Y+L++++L+R+ ++Y+ L L+    V P    +  VPVK+L+CDTI+Q KEK+LD +
Sbjct: 1480 EARYSLSEDKLIRQQIDYKTLVLSC---VSPDNANSPEVPVKILNCDTITQVKEKILDAI 1536

Query: 1789 YKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVA 1848
            +K VP + RP    +D+EWR G    +IL DED+T++++  W+RLNTL HY+VPDG+ VA
Sbjct: 1537 FKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVA 1596

Query: 1849 LVP--------------CLTKHVLRENQDYVPGE------RTPMLEDVDEGGIRPWHLVK 1888
            LV                 T     EN     G       RTPM+    E G++ WHLVK
Sbjct: 1597 LVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVK 1656

Query: 1889 PSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR--- 1945
              +  +     RGS         K + EIYLTRLL+ KGTLQKFVDDLF+ I ST+    
Sbjct: 1657 NHEHGDQKEGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGS 1707

Query: 1946 PVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNM 2005
             +PLA+KY FD LDEQA +HGI D    H WK+N LPLRFW+N+IKNPQFVFD+  +   
Sbjct: 1708 ALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSIT 1767

Query: 2006 DAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQ 2065
            DA L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK  VERYY+DI +    SDQ
Sbjct: 1768 DACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQ 1827

Query: 2066 EMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQI 2124
            +MN+ LAE S  +  +     AL E++ Y+ KY ++I+  L+ D    K +L Y+L+Q+
Sbjct: 1828 DMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQV 1886



 Score =  238 bits (607), Expect = 5e-62
 Identities = 182/663 (27%), Positives = 310/663 (46%), Gaps = 69/663 (10%)

Query: 37  HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQA-QPTN 95
           HL  D  +G +YLGA N +++LS  L++  T  TGP  D+  C PP +   C +    TN
Sbjct: 53  HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112

Query: 96  NPNQLLLVS--PGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153
           N N++LL+      L+ CGS++QG+C+  RL  L +L   P    +  Y++  + + S  
Sbjct: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLG-EPYHKKE-HYLSGVNESGSVF 170

Query: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALWP---PDPQAAFSYEETAKLAVGR 210
           G++      +  LF+       G     P I++R L      D   A+ + +    ++ +
Sbjct: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228

Query: 211 LS--------EYSHHFVSAFARGASAYFLFLRRDLQA------QSRAFRAYVSRVCLRDQ 256
           +         ++  ++V  F+ G   YFL L+ ++ +      + + + + + R+C  D 
Sbjct: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288

Query: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREVA--------HGEVLFAAFSSAAPPTVG 306
            + SYVE+P+ CE  G  Y L+QAA ++ +  V           ++LF  FS      + 
Sbjct: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMK 348

Query: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365
                   +   SALC F L +++        +CY  EG  +    +A+++  D+    A
Sbjct: 349 --------SLDESALCIFILKQINDRIKERLQSCYRGEGTLD----LAWLKVKDIPCSSA 396

Query: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425
            L   T+D   CG D   +P+     +   P+      ++T+V   +   H++AF+G   
Sbjct: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452

Query: 426 GQLHRVYL-GPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQ 484
           G+L ++ + GP  +   Y T  +     V RD+ F    E LY+M++  L +VPV SC Q
Sbjct: 453 GKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQ 512

Query: 485 HLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANI 544
           +  C  CL   DP+CGWCVL   C+R+  C R + P +    F  E+       + P NI
Sbjct: 513 YQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRR----FASEMKQCVRLTVHPNNI 568

Query: 545 SREETREVF-LSVPDLPPLWPGESYSCHFGE-HQSPALLTGSGVMCPSPDPSEAP-VLPR 601
           S  +   +  L   ++P L  G   +C F +  +   L+ G+ + C SP   E P ++  
Sbjct: 569 SVSQYNVLLVLETYNVPELSAG--VNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITE 626

Query: 602 GADYVSVSVELRF--GAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHL 659
             D+  V ++L+     +  A TS  FY+C           C +CV S + C+WC ++H+
Sbjct: 627 NGDHHVVQLQLKSKETGMTFASTSFVFYNCSV------HNSCLSCVESPYRCHWCKYRHV 680

Query: 660 CTH 662
           CTH
Sbjct: 681 CTH 683



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 52/204 (25%), Positives = 78/204 (38%), Gaps = 34/204 (16%)

Query: 481 SCAQHLDCASCLAHRDPY-CGWCVLLGRCSRRSE-CSRGQGPEQWLWSFQPELGCLQVAA 538
           +C+ H  C SC+    PY C WC     C+   + CS  +G  +      PE  C Q+  
Sbjct: 655 NCSVHNSCLSCV--ESPYRCHWCKYRHVCTHDPKTCSFQEGRVKL-----PE-DCPQLLR 706

Query: 539 MSPANISREETREVFLSVPDLPPLWPGE-SYSCHFG----EHQSPAL-LTGSGVMCPSPD 592
           +    +  E  + + L   +LP    G+  Y C       E + PAL    S V C +  
Sbjct: 707 VDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQNTS 766

Query: 593 PSEAPVLPRGADYVSVSVEL------RFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVS 646
            S       G +  ++ VEL       F     A+  +  Y C A+ E      C  C+ 
Sbjct: 767 YSY-----EGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRE-----SCGLCLK 816

Query: 647 SR--WGCNWCVWQHLCTHKASCDA 668
           +   + C WC     CT +  C A
Sbjct: 817 ADPDFACGWCQGPGQCTLRQHCPA 840



 Score = 35.0 bits (79), Expect = 0.79
 Identities = 45/178 (25%), Positives = 72/178 (40%), Gaps = 28/178 (15%)

Query: 476 KVPVASC-AQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGC 533
           KV +  C A    C  CL A  D  CGWC   G+C+ R  C   +   QWL     +  C
Sbjct: 798 KVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQE--SQWLELSGAKSKC 855

Query: 534 L--QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMC-PS 590
              ++  + P    RE   +V +          GE+    F +  S   +  +GV C P 
Sbjct: 856 TNPRITEIIPVTGPREGGTKVTIR---------GENLGLEFRDIASHVKV--AGVECSPL 904

Query: 591 PD---PSEAPVLPRG-------ADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPS 638
            D   P+E  V   G       A +V + V +     +   + L ++  + +++L+PS
Sbjct: 905 VDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPS 962


>gi|113722116 plexin A2 [Homo sapiens]
          Length = 1894

 Score =  788 bits (2036), Expect = 0.0
 Identities = 488/1272 (38%), Positives = 695/1272 (54%), Gaps = 132/1272 (10%)

Query: 910  ASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVEC 969
            +  CP +   +   L+PV   + I L  RNL   Q G    ECV+ ++G    V A    
Sbjct: 698  SEDCPQLVPTE-EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPAL--- 753

Query: 970  EPPPDTQCHVTCQQHQLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGD 1028
                     V CQ     Y+ +    L V   +   G   +D+ + L V LY C+     
Sbjct: 754  ---RFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRES 810

Query: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAV-------ATQCPAPLIHSVEPLTGP 1081
            C  C  A  ++ C WC GER RC   + C    +          +C  P I  +  ++GP
Sbjct: 811  CGLCLKADRKFECGWCSGER-RCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGP 869

Query: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
             +GGTRVTI G NLG    ++   V VAGVPC     EY ++  +VC     G  + G T
Sbjct: 870  PEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVC---EMGHALVGTT 926

Query: 1142 AV-------EVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLED 1194
            +        E        S   + + +P V S+ P RGP +GGT +T+ G  L  G    
Sbjct: 927  SGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAG--SS 984

Query: 1195 IRVVVGDQPCHLLPEQQSEQLRCETSPRPT---PATLPVAVWFGATERRLQRGQFKYTLD 1251
            + V +G+Q C       SE + C + P      P  + V+V     +  LQ   F+Y  D
Sbjct: 985  VAVYLGNQTCEFYGRSMSE-IVCVSPPSSNGLGPVPVSVSVDRAHVDSNLQ---FEYIDD 1040

Query: 1252 PNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETA 1311
            P +    P  S  SG   + + G NLDV+Q PRIRV                        
Sbjct: 1041 PRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKF---------------------- 1078

Query: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPAL-----PGLP--EDPWVRVEFILDNLVFDF 1364
                   + ++    C V ++  +TC  P+L     PGL   E P     F+ +N V   
Sbjct: 1079 -------NGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERP-DEFGFVFNN-VQSL 1129

Query: 1365 ATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMS---KEEVVAMIG 1421
               N T F Y  +PT + L+P   T     KPGS   ++G+NL    S   K     +IG
Sbjct: 1130 LIYNDTKFIYYPNPTFELLSP---TGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIG 1186

Query: 1422 DGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGES 1481
            + PC V T++   L CEPP    L   H +           V +G + FS G V    +S
Sbjct: 1187 ETPCAV-TVSETQLLCEPP---NLTGQHKVM----------VHVGGMVFSPGSVSVISDS 1232

Query: 1482 PGAFPVAAQVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCK 1541
                P  A V +  G SLL + VII+++ Y+RKS++     K++Q+Q++NLES V   CK
Sbjct: 1233 LLTLP--AIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECK 1290

Query: 1542 KEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQ 1601
            + F +L T++ +LTSDL  SGIP+LDY+ YA R+ FPG  + P+ R+L V  + +  VE+
Sbjct: 1291 EAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQHVEK 1350

Query: 1602 GLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLS 1661
             L   + L+N+K+FL  FI TLE QR+FS RDR  VASL+   L G+LEY TD+L+ LLS
Sbjct: 1351 ALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLS 1410

Query: 1662 DLVAQYVAK--NPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVD 1719
            DL+ + +    +PKL+LRRTE+V EK+LTNW +  L+ F+++  GEPL+ML+  IK Q++
Sbjct: 1411 DLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQME 1470

Query: 1720 KGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQ 1779
            KGP+D++TG+A+Y+L++++L+R+ +EY+ L LN    V P    +  +PVKVL+CDTI+Q
Sbjct: 1471 KGPIDAITGEARYSLSEDKLIRQQIEYKTLILNC---VNPDNENSPEIPVKVLNCDTITQ 1527

Query: 1780 AKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHY 1839
             KEK+LD +YK VP +QRP    +D+EWR G    ++L DED+T++++G W+RLNTL HY
Sbjct: 1528 VKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHY 1587

Query: 1840 KVPDGATVALVPCLTKH-------------VLRENQDY-------VPGERTPMLEDVDEG 1879
            +V D + VALVP  T               + R +  +           R PM+    E 
Sbjct: 1588 QVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLES 1647

Query: 1880 GIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQV 1939
            G++ WHLVK  D  +     RGS         K + EIYLTRLL+ KGTLQKFVDDLF+ 
Sbjct: 1648 GVKVWHLVKNHDHGDQKEGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFET 1698

Query: 1940 ILST---SRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFV 1996
            + ST      +PLA+KY FD LDEQA +H I D D  H WK+N LPLRFW+N+IKNPQFV
Sbjct: 1699 LFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFV 1758

Query: 1997 FDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADI 2056
            FD+      DA L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK  VERYYADI
Sbjct: 1759 FDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADI 1818

Query: 2057 RQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQ 2116
             +    SDQ+MN+ LAE S  ++ +     AL+E+Y Y++KY +++I ALE+D  A++ +
Sbjct: 1819 AKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQR 1878

Query: 2117 LGYRLQQIAAAV 2128
            L Y+++Q+  A+
Sbjct: 1879 LAYKVEQLINAM 1890



 Score =  275 bits (702), Expect = 5e-73
 Identities = 218/745 (29%), Positives = 345/745 (46%), Gaps = 89/745 (11%)

Query: 16  WVLTLQPLPPTAFTPNGTYLQHLARDPT---------SGTLYLGATNFLFQLSPGLQLEA 66
           WVL     PP A  P  +      RD T         +G +Y+GA N +++L+  L ++ 
Sbjct: 25  WVLLA---PPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQV 81

Query: 67  TVSTGPVLDSRDCLPPVMPDECPQAQP-TNNPNQLLLV--SPGALVVCGSVHQGVCEQRR 123
              TGP  D++ C PP++   C +    TNN N+LL++  S   L+ CGS++QGVC+  R
Sbjct: 82  AHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLR 141

Query: 124 LGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPP 183
           L  L  +L+ P    +  Y+++ +   +  G++ +    +  LF+G      G     P 
Sbjct: 142 LDDLF-ILVEPSHKKE-HYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVD--GKQDYFPT 197

Query: 184 ITTRALWPPDPQ--AAFSYE-------ETAKLAVGRLSEYSHH---FVSAFARGASAYFL 231
           +++R L P DP+  A   YE          K+    L+  SH    ++  FA G   YFL
Sbjct: 198 LSSRKL-PRDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFL 256

Query: 232 FLRRDL-------QAQSRAFRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQAAAVA 282
            ++ +         A    + + + R+C  D  ++SYV LP  C   G  Y L+QAA +A
Sbjct: 257 TVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLA 316

Query: 283 TSRE--------VAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLAN 334
              +         +  +VLFA FS         PP         SALCAFP+  ++    
Sbjct: 317 KPGDSLAQAFNITSQDDVLFAIFSKGQKQ-YHHPPDD-------SALCAFPIRAINLQIK 368

Query: 335 RTRDACYTREGRAEDGTEVAYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMASRVPL 392
               +CY  EG  E       + + +  D  C + PV   D + CG D    P+    P+
Sbjct: 369 ERLQSCYQGEGNLE-------LNWLLGKDVQCTKAPVPIDDNF-CGLDIN-QPLGGSTPV 419

Query: 393 EATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYL-GPGSDGHPYSTQSI-QQG 450
           E   +      ++T+VA  + +G+++ F+G   G+L ++   GP   G  Y   S+ + G
Sbjct: 420 EGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDG 479

Query: 451 SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSR 510
           S + RD+ F     +LYVM++  + +VPV SC Q+  C  CL+  DP+CGWC L   CSR
Sbjct: 480 SPILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSR 539

Query: 511 RSECSRGQGPEQWLWSFQPELGCLQVAAMSPANIS-REETREVFLSVPDLPPLWPGESYS 569
           R +C +   P ++  S      C+ + A+ P++IS  E +R + L V D P L  G   +
Sbjct: 540 RDKCQQAWEPNRFAASISQ---CVSL-AVHPSSISVSEHSRLLSLVVSDAPDLSAG--IA 593

Query: 570 CHFGE-HQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAV--VIAKTSLSF 626
           C FG   +    ++GS V+C SP P + PV+P   D+  + ++LR      +   T   F
Sbjct: 594 CAFGNLTEVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKF 653

Query: 627 YDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCTH---KASCDAGPMVASHQSPLVSPD 683
           Y+C A         C +CV+S + C+WC +++LCTH     S   G +  S   P + P 
Sbjct: 654 YNCSA------HQLCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCPQLVPT 707

Query: 684 PPARGGPSPSPPTAPKALATPAPDT 708
                      P   KA   P P +
Sbjct: 708 EEILIPVGEVKPITLKARNLPQPQS 732



 Score = 35.4 bits (80), Expect = 0.60
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 20/114 (17%)

Query: 425 QGQLHRVYLGPGSDGHPYSTQSIQ-QGSAVSRD--------LTFDGTFEHLYVMTQSTLL 475
           QG +HRV          +++ S+Q Q S+   D        + F   +   +++     L
Sbjct: 744 QGAIHRV------PALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDL 797

Query: 476 KVPVASCA-QHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWL-WS 526
           KV +  CA Q   C  CL A R   CGWC    RC+    C+    P  WL WS
Sbjct: 798 KVHLYKCAAQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSSP--WLDWS 849



 Score = 35.0 bits (79), Expect = 0.79
 Identities = 48/203 (23%), Positives = 72/203 (35%), Gaps = 36/203 (17%)

Query: 481 SCAQHLDCASCL--AHRDPYCGWCVLLGRCSRR-SECSRGQGPEQWLWSFQPELGCLQVA 537
           +C+ H  C SC+  A R   C WC     C+   + CS  +G             C Q+ 
Sbjct: 655 NCSAHQLCLSCVNSAFR---CHWCKYRNLCTHDPTTCSFQEG------RINISEDCPQLV 705

Query: 538 AMSPANISREETREVFLSVPDLPPLWPGE-SYSCHFGE----HQSPAL-LTGSGVMCPSP 591
                 I   E + + L   +LP    G+  Y C        H+ PAL    S V C + 
Sbjct: 706 PTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQCQNS 765

Query: 592 DPSEAPVLPRGADYVSVSVELRF---GAVVIAKTS---LSFYDCVAVTELRPSAQCQACV 645
                     G D  +++V+      G  +I       +  Y C A  E      C  C+
Sbjct: 766 SYQYD-----GMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRE-----SCGLCL 815

Query: 646 SS--RWGCNWCVWQHLCTHKASC 666
            +  ++ C WC  +  CT    C
Sbjct: 816 KADRKFECGWCSGERRCTLHQHC 838


>gi|157694524 plexin D1 [Homo sapiens]
          Length = 1925

 Score =  759 bits (1961), Expect = 0.0
 Identities = 473/1199 (39%), Positives = 676/1199 (56%), Gaps = 131/1199 (10%)

Query: 979  VTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQ 1038
            V C Q  L          + L L+      +DS E + V++Y+C++G  DCS+C      
Sbjct: 806  VRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQC-LGRED 864

Query: 1039 YG--CVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLG 1096
             G  C+W +G R R       G  + +A  CPAP I ++EPL+GP+DGGT +TIRG NLG
Sbjct: 865  LGHLCMWSDGCRLR-------GPLQPMAGTCPAPEIRAIEPLSGPLDGGTLLTIRGRNLG 917

Query: 1097 QHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRGRGVSEHD 1156
            + + DV   V + GV C      Y VS  +VC+TG +   ++G   V     G+  S   
Sbjct: 918  RRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKEGK--SRDR 975

Query: 1157 FAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD-QPCHLLPEQQSEQL 1215
            F+Y  P VHS+ P  GP+AGGTR+T++G+ L  G   +++V+V D  PC  L    +  +
Sbjct: 976  FSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVG--SELQVLVNDTDPCTELMRTDTS-I 1032

Query: 1216 RCETSPRPTPATLPVAVWFGATERR-LQRGQ--FKYTLDPNITSAGPTKSFLSGGREICV 1272
             C       PA +PV V F   ERR    G   F Y  +P IT+  P +S +SGGR I V
Sbjct: 1033 ACTMPEGALPAPVPVCVRF---ERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITV 1089

Query: 1273 RGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEP--CHVN 1330
             G+   +VQ   + V  + R                                EP  C V 
Sbjct: 1090 AGERFHMVQNVSMAVHHIGR--------------------------------EPTLCKVL 1117

Query: 1331 SSQLITCRTPAL---PGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPL-NPE 1386
            +S LITC +P        P D ++      D +      L+P      +   L  L NP+
Sbjct: 1118 NSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQ 1177

Query: 1387 DPTMP----FRHKPGSVFS--VEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
              T       +H PG   +  +  E   L +   E    IG   C ++ ++   ++C   
Sbjct: 1178 FSTAKREKWIKHHPGEPLTLVIHKEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSV- 1236

Query: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
                   + +L  A   LP  T+Q+GN   ++  +Q  G        A  V + + + LL
Sbjct: 1237 -------NESLGAAVGQLP-ITIQVGNFNQTIATLQLGGSE-----TAIIVSIVICSVLL 1283

Query: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
             L V+ +  ++  KS++A R ++K  +Q+E +ES +R+  +K F +L T+MTDLT +L  
Sbjct: 1284 LLSVVAL-FVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNR 1342

Query: 1561 S-GIPFLDYKVYAERIFFP------------------------GHRESPLHRDLGVPESR 1595
            S GIPFL+YK +  R FFP                             PL  +  +PES 
Sbjct: 1343 SQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESC 1402

Query: 1596 RPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDI 1655
            RP +E+G+   S+LLN+K FL  F+H LE Q+ F+ RDR  +ASLLT+ALHGKLEY+T I
Sbjct: 1403 RPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSI 1462

Query: 1656 LRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIK 1715
            ++ LL DL+    AKNPKLMLRRTE+VVEK+LTNWMSIC+Y+ +R++VGEP ++L   IK
Sbjct: 1463 MKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIK 1522

Query: 1716 HQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCD 1775
             Q++KG +D++TGKA+YTLN+  LLRE++E +P  LN       G G    + V+ +D D
Sbjct: 1523 QQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNVSFQ---GCG-MDSLSVRAMDTD 1578

Query: 1776 TISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNT 1835
            T++Q KEK+L+   K VP +Q P    +D+EW +      IL D D TS V+   ++LNT
Sbjct: 1579 TLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNT 1638

Query: 1836 LQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDE-PE 1894
            L HYK+P+GA++A+        L + +D   G     ++D+D    + +HLV P+DE  E
Sbjct: 1639 LAHYKIPEGASLAMS-------LIDKKDNTLGR----VKDLDTE--KYFHLVLPTDELAE 1685

Query: 1895 PPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVP-LAVKY 1953
            P +  R S       R K +PEIYLTRLLS KGTLQKF+DDLF+ ILS     P LAVKY
Sbjct: 1686 PKKSHRQS------HRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKY 1739

Query: 1954 FFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIA 2013
            FFD L+EQA++ GISD DT+HIWKTNSLPLRFW+NI+KNPQFVFD+  +D++DA L VIA
Sbjct: 1740 FFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIA 1799

Query: 2014 QTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAE 2073
            Q F+DAC+++D +LG+DSP NKLLYA++IP Y+++V+RYY  I+   P S+QEMN+ LAE
Sbjct: 1800 QAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAE 1859

Query: 2074 LSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKV 2132
             S  Y  +    VA+ E+YKY  +Y  QI+ ALE + TA++ QL ++ +Q+ A +E+ +
Sbjct: 1860 ESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNI 1918



 Score =  251 bits (642), Expect = 4e-66
 Identities = 222/742 (29%), Positives = 325/742 (43%), Gaps = 107/742 (14%)

Query: 30  PNGTYLQHLARDPTSGTLYLGATNFLFQLS-PGLQLEATVSTGPVLDSRDCLPPVMPD-- 86
           P+ T   + A D  +GT+YL A N L+QLS   L LEA  + GPV DS  C  P +P   
Sbjct: 54  PSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQAS 113

Query: 87  -ECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLR------PERP 137
            E P+ + T+N N++L + PG   +VVCGS++QG C+ RR G +  + +R      P  P
Sbjct: 114 CEHPR-RLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEP 172

Query: 138 ----GDTQYVAANDPAVSTVGLV---AQGLAGEPLLFVGRGYTSRGVG------------ 178
                    VAAN P  STVGLV   A G  G  LL VG  YT  G              
Sbjct: 173 VTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLL-VGATYTGYGSSFFPRNRSLEDHR 231

Query: 179 -GGIPPITTRALWPPDPQAAF-------SYEETAKLAVGRLSEYSHHFVSAFAR------ 224
               P I  R+L      A         S +   K+  G   ++   FVSAF        
Sbjct: 232 FENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPP 291

Query: 225 GASAY-FLFLRRDLQA---QSRAFRAYVSRVCL-------RDQHYYSYVELPLACEGGR- 272
           GA +Y +L L  + +A   +S+A R+ ++R+CL         +   SY++L L C GG  
Sbjct: 292 GAQSYAYLALNSEARAGDKESQA-RSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAG 350

Query: 273 ----YGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDE 328
               Y  + +   A  R       LFA F         RP  + A  +  +ALCAF   +
Sbjct: 351 RGDLYSRLVSVFPARER-------LFAVFE--------RPQGSPAARAAPAALCAFRFAD 395

Query: 329 VDRLANRTRDACYTREG--------RAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSD 380
           V       R AC+                GT  A  E  +N    QL  + LD   CG+ 
Sbjct: 396 VRAAIRAARTACFVEPAPDVVAVLDSVVQGTGPA-CERKLN---IQLQPEQLD---CGAA 448

Query: 381 HTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGH 440
           H   P++   PL+ATP+   PG  LT+VAV   + +T  FLG   G+L ++ L       
Sbjct: 449 HLQHPLSILQPLKATPVFRAPG--LTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVV 506

Query: 441 PYSTQSIQQGSAVSRDLTFDGTFE-HLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYC 499
                ++  G  V   + FD     +LY+MT   + +V VA+C  H  C  C+   D YC
Sbjct: 507 SRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYC 566

Query: 500 GWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDL 559
           GWC L  RC+ + +C+       W  + +    C  +  +      R+E   + L +   
Sbjct: 567 GWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGS 626

Query: 560 PPLWPGESYSCHFGEH-QSPALLTGSG-----VMCPSPDPSEAPVLPRGADYVSVSVELR 613
            P   G   +C +G + ++ A + G         C      + P  P   D+V+V + +R
Sbjct: 627 LPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVR 686

Query: 614 FGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC-THKASCDAGPMV 672
                I K + + YDC    ++ P   C +C+S++W C WC  QH C ++++ C+A P  
Sbjct: 687 VNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNP 746

Query: 673 ASHQS---PLVSPDPPARGGPS 691
            S Q     L+SP  P   G S
Sbjct: 747 TSPQDCPRTLLSPLAPVPTGGS 768


>gi|59710104 plexin A3 [Homo sapiens]
          Length = 1871

 Score =  751 bits (1940), Expect = 0.0
 Identities = 475/1263 (37%), Positives = 690/1263 (54%), Gaps = 136/1263 (10%)

Query: 921  GSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPPPDTQCHVT 980
            G  L+PV V + + L  +NL   Q G  + ECV+ ++G +  V A             V 
Sbjct: 690  GDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPA------VRFNSSSVQ 743

Query: 981  CQQHQLSYEALQP-ELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQY 1039
            CQ    SYE  +  +  +   +   G   +D       +LY C      C  C  A P++
Sbjct: 744  CQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRF 803

Query: 1040 GCVWCEGERPRCVTREACGEAEA-------VATQCPAPLIHSVEPLTGPVDGGTRVTIRG 1092
             C WC  E  RC  R  C   +          T+C  P I  + PL GP +GGTRVTI G
Sbjct: 804  NCGWCISEH-RCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVG 862

Query: 1093 SNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEV-----PG 1147
             NLG   ++V   + VAGV C     EY  +  +VC    S         VE+       
Sbjct: 863  DNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSA 920

Query: 1148 RGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLL 1207
              R  SE  +++  P    + P+RGP +GGTRLT++GS L  G    + V V D  C  +
Sbjct: 921  DFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAG--SRVTVTVRDSECQFV 978

Query: 1208 PEQQSEQLRCETSPRPT--PATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSFLS 1265
              + ++ + C  SP  T  P+  P+ +             + YT DP +T   PT S ++
Sbjct: 979  -RRDAKAIVC-ISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIIN 1036

Query: 1266 GGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEE 1325
            G   I V G +L  VQ PR+R                + R +  T               
Sbjct: 1037 GSTAITVSGTHLLTVQEPRVRA---------------KYRGIETT--------------N 1067

Query: 1326 PCHVNSSQLITCRTPAL-PGLPEDPWVRVE------FILDNLVFDFATLNPTPFSYEADP 1378
             C V +   + C+ P +  G P+ P  + E      F+LD+ V    +LN + F+Y  DP
Sbjct: 1068 TCQVINDTAMLCKAPGIFLGRPQ-PRAQGEHPDEFGFLLDH-VQTARSLNRSSFTYYPDP 1125

Query: 1379 TLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAM---SKEEVVAMIGDGPCVVKTLTRHHL 1435
            + +PL P         KPGS   ++G+NL  A    S+     +IG  PC + T++   L
Sbjct: 1126 SFEPLGPSGV---LDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSL-TVSDTQL 1181

Query: 1436 YCEPPVE---QPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVG 1492
             C+ P +   QP+                 V +G L F LG +    E   A  + A +G
Sbjct: 1182 LCDSPSQTGRQPV----------------MVLVGGLEFWLGTLHISAER--ALTLPAMMG 1223

Query: 1493 LGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMT 1552
            L  G  LL L +  +++ Y+RK++ A R  K++Q+Q++NLES V   CK+ F +L T++ 
Sbjct: 1224 LAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIN 1283

Query: 1553 DLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLLNS 1612
            +LT+ +    IPFLDY+ YA R+ FPG    P+ ++L  P    P VE+ L     LL+S
Sbjct: 1284 ELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP----PNVEKALRLFGQLLHS 1339

Query: 1613 KLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-AKN 1671
            + F+  FIHTLE+Q +FS RDR  VASL  VAL  +L+Y T +L+ LL+DL+ + + +KN
Sbjct: 1340 RAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKN 1399

Query: 1672 -PKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKA 1730
             PKL+LRRTE+V EK+LTNW +  L+ F+++  GEPL++L+  IK Q++KGP+D++TG+A
Sbjct: 1400 HPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEA 1459

Query: 1731 KYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQLYK 1790
            +Y+L++++L+R+ ++Y+ LTL+ +     G+ +   VPVKVL+CD+I+QAK+K+LD +YK
Sbjct: 1460 RYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQ---VPVKVLNCDSITQAKDKLLDTVYK 1516

Query: 1791 GVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALV 1850
            G+P +QRP    +D+EWR G    +IL DEDVT++++  W+RLN+L HY+V DG+ VALV
Sbjct: 1517 GIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALV 1576

Query: 1851 P------------CLTKHVLR--------ENQDYVPGERTPMLEDVDEGGIRPWHLVKPS 1890
            P              T+ + R         + D +   R PM+    E G + WHLVK  
Sbjct: 1577 PKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSL-RSRAPMITPDQETGTKLWHLVKNH 1635

Query: 1891 DEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR---PV 1947
            D  +     RGS         K + EIYLTRLL+ KGTLQKFVDDLF+ + ST+     +
Sbjct: 1636 DHADHREGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSAL 1686

Query: 1948 PLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDA 2007
            PLA+KY FD LDEQA Q  ISD D  H WK+N LPLRFW+N+IKNPQFVFD+  +   DA
Sbjct: 1687 PLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDA 1746

Query: 2008 VLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEM 2067
             L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK  VERYY DI +    SDQ+M
Sbjct: 1747 CLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDM 1806

Query: 2068 NSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAA 2127
            ++ L E S  ++ D     AL+ELY Y+ KY  +I+TAL+ D + +K +L  +L+QI + 
Sbjct: 1807 DAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISL 1866

Query: 2128 VEN 2130
            V +
Sbjct: 1867 VSS 1869



 Score =  249 bits (635), Expect = 3e-65
 Identities = 209/723 (28%), Positives = 320/723 (44%), Gaps = 76/723 (10%)

Query: 1   MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSP 60
           MP++   LL  L  G  L  +P    AF    T L HLA    +G +++GA N +F+L+P
Sbjct: 1   MPSVCLLLLLFLAVGGALGNRPF--RAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAP 58

Query: 61  GL-QLEATVSTGPVLDSRDCLPPVMPDECP-QAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
            L +L A V TGPV D+  C PP     C  +  P +N N+LLL+   A  LV CGS+ Q
Sbjct: 59  NLTELRAHV-TGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQ 117

Query: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
           G+C+  RL  L +L   P    +     A +P  S  G++ +   G   LFVG      G
Sbjct: 118 GICQFLRLDDLFKLG-EPHHRKEHYLSGAQEPD-SMAGVIVEQGQGPSKLFVGTAVD--G 173

Query: 177 VGGGIPPITTRALWPPDPQA---AFSYEET-----AKLAVGRLSEYSH---HFVSAFARG 225
                P +++R L   +  A   +  Y++       K+    LS Y     +++  F   
Sbjct: 174 KSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSA 233

Query: 226 ASAYFLFLRRDLQ------AQSRAFRAYVSRVCLRDQHYYSYVELPLACE--GGRYGLIQ 277
           +  YFL L+ D Q      A  + F + + R+C  D  +YSYVE P+ C   G  Y L+Q
Sbjct: 234 SFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQ 293

Query: 278 AAAVATSREV--------AHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEV 329
           +A +A    +        A  +VLF  FS         P          + LC F L  +
Sbjct: 294 SAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ--------TILCLFTLSNI 345

Query: 330 DRLANRTRDACYTREGRAEDGTEVAYIEYDVNSD--CAQLPVDTLDAYPCGSDHTPSPMA 387
           +    R   +CY  EG          + + +N +  C   P+  ++   CG      P+ 
Sbjct: 346 NAHIRRRIQSCYRGEGTLA-------LPWLLNKELPCINTPMQ-INGNFCGLVLN-QPLG 396

Query: 388 SRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI 447
               +E  P+L      + +VA      H++ F+G   G L +V +    D H Y T  +
Sbjct: 397 GLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPV 456

Query: 448 QQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGR 507
             GS + RDL F     H+Y++++  + ++PV +C Q+  CA+CL   DP+CGWCVL  R
Sbjct: 457 VDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHR 516

Query: 508 CSRRSECSRGQGPEQWLWSFQPELG-CLQVAAMSPANIS-REETREVFLSVPDLPPLWPG 565
           C R   C     P      F  EL  C+QV  + P N+S      ++ +++ ++P L  G
Sbjct: 517 CCREGACLGASAPH----GFAEELSKCVQV-RVRPNNVSVTSPGVQLTVTLHNVPDLSAG 571

Query: 566 ESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRG---ADYVSVSVELRFGAVVIAKT 622
            S +          LL    ++CPSP   E   L RG      V + +  +   V  A  
Sbjct: 572 VSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGA 631

Query: 623 SLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLCT---HKASCDAGPMVASHQSPL 679
              FY+C  +        C +CV S + C+WC ++H CT   H+ S   G + +    P 
Sbjct: 632 DFVFYNCSVL------QSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPE 685

Query: 680 VSP 682
           + P
Sbjct: 686 ILP 688



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 74/293 (25%), Positives = 115/293 (39%), Gaps = 49/293 (16%)

Query: 401 PGIQLTAVAVTMED---GHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQGSAVSRDL 457
           PG+QLT     + D   G + AF  ++  +   V L  G    P  + S+Q+  A++R  
Sbjct: 554 PGVQLTVTLHNVPDLSAGVSCAF--EAAAENEAVLLPSGELLCP--SPSLQELRALTRGH 609

Query: 458 TFDGTFEHLYVMTQSTLLKVPVA-----SCAQHLDCASCLAHRDPYCGWCVLLGRC-SRR 511
               T   L ++++ T ++   A     +C+    C SC+    P C WC     C SR 
Sbjct: 610 GATRTVR-LQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYP-CHWCKYRHTCTSRP 667

Query: 512 SECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDLPPLWPGE-SYSC 570
            ECS  +G         PE GC ++       I     + + L   +LP    G+ +Y C
Sbjct: 668 HECSFQEGRVH-----SPE-GCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYEC 721

Query: 571 ----HFGEHQSPAL-LTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLS 625
                  + + PA+    S V C +   S       G ++     EL F  V      + 
Sbjct: 722 VVRVQGRQQRVPAVRFNSSSVQCQNASYSY-----EGDEHGDT--ELDFSVVWDGDFPID 774

Query: 626 --------FYDCVAVTELRPSAQCQACVSS--RWGCNWCVWQHLCTHKASCDA 668
                    Y C A    RPS  C  C+ +  R+ C WC+ +H C  +  C A
Sbjct: 775 KPPSFRALLYKCWAQ---RPS--CGLCLKADPRFNCGWCISEHRCQLRTHCPA 822


>gi|5032223 plexin C1 [Homo sapiens]
          Length = 1568

 Score =  405 bits (1042), Expect = e-112
 Identities = 297/891 (33%), Positives = 436/891 (48%), Gaps = 105/891 (11%)

Query: 1244 GQFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRR 1303
            G   Y   P+ +   P  +++SGG+ I + G+N DV+        ++S  L+ +  +   
Sbjct: 746  GSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVIDN-----LIISHELKGNINVSE- 799

Query: 1304 RRVVPETACS-LGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVF 1362
                  T C  L PS  S +                            V V+  + +   
Sbjct: 800  --YCVATYCGFLAPSLKSSKVRTN------------------------VTVKLRVQDTYL 833

Query: 1363 DFATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGD 1422
            D  TL      Y  DP       E               ++ EN +  +SK+++   +  
Sbjct: 834  DCGTLQ-----YREDPRFTGYRVESEV-----DTELEVKIQKENDNFNISKKDIEITLFH 883

Query: 1423 GP-----CVVKTLTRHHLYCEPPVEQPLPRHHALREAP---DSLPEFTVQMGNLRFSLGH 1474
            G      C  + +TR+       +   L +   ++ A    +S  +  V++GNL   +  
Sbjct: 884  GENGQLNCSFENITRNQ-----DLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVE- 937

Query: 1475 VQYDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLES 1534
             Q    S   F +   V       LL + +   V + R KSK+  R   K   QLE LES
Sbjct: 938  -QESVPSTWYFLIVLPV-------LLVIVIFAAVGVTRHKSKELSR---KQSQQLELLES 986

Query: 1535 SVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERIFFP--GHRESPLHRDLGVP 1592
             +R   +  F +L  +  D+  D  G+ +PFLDYK +A R FFP  G        D+   
Sbjct: 987  ELRKEIRDGFAELQMDKLDVV-DSFGT-VPFLDYKHFALRTFFPESGGFTHIFTEDMHNR 1044

Query: 1593 ESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYF 1652
            ++      + L  L  L+ +K FL   IHTLE Q+ FS +DR   AS LT+AL  KL Y 
Sbjct: 1045 DANDKN--ESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYL 1102

Query: 1653 TDILRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFR 1712
            T IL  L  DL+ Q     PKLMLRRTE+VVEKLLTNWMS+CL  F+R++VGEP Y+L  
Sbjct: 1103 TSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVT 1162

Query: 1713 GIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGP---GAGEAQGVPV 1769
             +  +++KGPVD +T KA YTLN++ LL +  E+  + LN +    P    A   + + V
Sbjct: 1163 TLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISV 1222

Query: 1770 KVLDCDTISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGL 1829
             VLDCDTI QAKEK+                  + +E + G     +L  +  +  ++  
Sbjct: 1223 NVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDG 1282

Query: 1830 WRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKP 1889
              +LNT+ HY++ +G+T+ +   +                T  +E  D+      HL+ P
Sbjct: 1283 ITKLNTIGHYEISNGSTIKVFKKIANF-------------TSDVEYSDD----HCHLILP 1325

Query: 1890 SDEPEPPRPRRGSLRGGERERAK---AIPEIYLTRLLSMKGTLQKFVDDLFQVILS-TSR 1945
              E             G+R R K    + E+YLT+LLS K  +   ++ LF+ I S  + 
Sbjct: 1326 DSEAFQDVQ-------GKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS 1378

Query: 1946 PVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNM 2005
              P A+KYFFD LD QA+   I+D D +HIWKTNSLPLRFW+NI+KNPQFVFD++ + ++
Sbjct: 1379 RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHI 1438

Query: 2006 DAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQ 2065
            D  L VIAQ FMDA +L + +LG+++P NKLLYA+DIP YK  V+ YY  IR   P S  
Sbjct: 1439 DGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSS 1498

Query: 2066 EMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQ 2116
            EM   L + S  +  +    VAL E+YKYI KY+D+I+  LE +   ++ Q
Sbjct: 1499 EMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQ 1549



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 149/637 (23%), Positives = 244/637 (38%), Gaps = 102/637 (16%)

Query: 78  DCLPPVMPDECPQAQPTNNPNQLLL------VSPGALVVCG-SVHQGVCEQRRLGQLEQL 130
           +C  PV      + +P ++ ++LLL         G L++ G +  +G CE R LG L + 
Sbjct: 86  NCTEPVSLAPPARPRPGSSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRN 145

Query: 131 LLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW 190
            LR      T+ V+ + P  ST G+V +  AG       R Y +      +P   T +  
Sbjct: 146 SLR----NGTEVVSCH-PQGSTAGVVYR--AGRN----NRWYLAVAATYVLPEPETASRC 194

Query: 191 PP---DPQAAFSYEET-----AKLAVGRLS----EYSHHFVSAFARGASAYFLFLRRDLQ 238
            P   D   A + ++T     A   +GRL       S HFV AF    S YF +   +  
Sbjct: 195 NPAASDHDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYPYNYT 254

Query: 239 AQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYG---LIQAAAVATSREVAHGEVLFA 295
           + +      ++R+    +  +   +  L C  G      L+ ++++  + +V  G     
Sbjct: 255 SGAATGWPSMARIAQSTEVLFQG-QASLDCGHGHPDGRRLLLSSSLVEALDVWAG----- 308

Query: 296 AFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
            FS+AA     R           +ALC F + E+   A R      T E   ++G +   
Sbjct: 309 VFSAAAGEGQERRSPTT------TALCLFRMSEIQARAKRVSWDFKTAESHCKEGDQPER 362

Query: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
           ++                           P+AS   + +          LT+V  T+   
Sbjct: 363 VQ---------------------------PIASSTLIHS---------DLTSVYGTVVMN 386

Query: 416 HTIAFLGDSQGQLHRVYLGPGSDGH-PYSTQSIQQGSAVSRDLTFDGTFE-HLYVMTQST 473
            T+ FLG   GQL +V LG     + P     I++ + V   L  D     ++Y+     
Sbjct: 387 RTVLFLGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKE 446

Query: 474 LLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGC 533
           + ++ VA+C +H  C+ CL   DP+CGWC  L RC+ + +C   +  E WL       G 
Sbjct: 447 VRRIRVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWL---DISSGA 503

Query: 534 LQVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDP 593
            +   +     S+E+T     +V  +    P  S         S  L          P+ 
Sbjct: 504 KKCPKIQIIRSSKEKT-----TVTMVGSFSPRHSKCMVKNVDSSRELCQNKS----QPNR 554

Query: 594 SEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNW 653
           +    +P  A Y  VSV      V+ +  S +  D    T      +C ACV +  GC W
Sbjct: 555 TCTCSIPTRATYKDVSVV----NVMFSFGSWNLSDRFNFTNCSSLKECPACVET--GCAW 608

Query: 654 CVWQHLCTHK-ASCDAGPMVASHQSPLVSPDPPARGG 689
           C     C H   +CD      + +   V+ +  + GG
Sbjct: 609 CKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGG 645


>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
          Length = 522

 Score =  119 bits (299), Expect = 2e-26
 Identities = 111/434 (25%), Positives = 198/434 (45%), Gaps = 52/434 (11%)

Query: 37  HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ-AQPTN 95
           HL  D  +G +YLGA N +++LS  L++  T  TGP  D+  C PP +   C +    TN
Sbjct: 53  HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112

Query: 96  NPNQLLLV--SPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153
           N N++LL+      L+ CGS++QG+C+  RL  L + L  P    +  Y++  + + S  
Sbjct: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFK-LGEPYHKKE-HYLSGVNESGSVF 170

Query: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW---PPDPQAAFSYEETAKLAVGR 210
           G++      +  LF+       G     P I++R L      D   A+ + +    ++ +
Sbjct: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228

Query: 211 --------LSEYSHHFVSAFARGASAYFLFLRRDL------QAQSRAFRAYVSRVCLRDQ 256
                   + ++  ++V  F+ G   YFL L+ ++        + + + + + R+C  D 
Sbjct: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288

Query: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREV--------AHGEVLFAAFSSAAPPTVG 306
            + SYVE+P+ CE  G  Y L+QAA ++ +  V           ++LF  FS        
Sbjct: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFS-------- 340

Query: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365
           +       +   SALC F L +++        +CY    R E   ++A+++  D+    A
Sbjct: 341 KGQKRKMKSLDESALCIFILKQINDRIKERLQSCY----RGEGTLDLAWLKVKDIPCSSA 396

Query: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425
            L   T+D   CG D   +P+     +   P+      ++T+V   +   H++AF+G   
Sbjct: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452

Query: 426 GQLHRVYLGPGSDG 439
           G+L + + G G  G
Sbjct: 453 GKLKKSF-GTGPQG 465


>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
          Length = 492

 Score =  119 bits (297), Expect = 4e-26
 Identities = 114/445 (25%), Positives = 203/445 (45%), Gaps = 56/445 (12%)

Query: 37  HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ-AQPTN 95
           HL  D  +G +YLGA N +++LS  L++  T  TGP  D+  C PP +   C +    TN
Sbjct: 53  HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112

Query: 96  NPNQLLLV--SPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153
           N N++LL+      L+ CGS++QG+C+  RL  L + L  P    +  Y++  + + S  
Sbjct: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFK-LGEPYHKKE-HYLSGVNESGSVF 170

Query: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALW---PPDPQAAFSYEETAKLAVGR 210
           G++      +  LF+       G     P I++R L      D   A+ + +    ++ +
Sbjct: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228

Query: 211 --------LSEYSHHFVSAFARGASAYFLFLRRDL------QAQSRAFRAYVSRVCLRDQ 256
                   + ++  ++V  F+ G   YFL L+ ++        + + + + + R+C  D 
Sbjct: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288

Query: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREV--------AHGEVLFAAFSSAAPPTVG 306
            + SYVE+P+ CE  G  Y L+QAA ++ +  V           ++LF  FS        
Sbjct: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFS-------- 340

Query: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365
           +       +   SALC F L +++        +CY    R E   ++A+++  D+    A
Sbjct: 341 KGQKRKMKSLDESALCIFILKQINDRIKERLQSCY----RGEGTLDLAWLKVKDIPCSSA 396

Query: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425
            L   T+D   CG D   +P+     +   P+      ++T+V   +   H++AF+G   
Sbjct: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452

Query: 426 GQLHRVYLGPGSDGHPYSTQSIQQG 450
           G+L ++   PG+   P  T  +Q G
Sbjct: 453 GKLKKM---PGTSLCP--TLELQTG 472


>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
          Length = 1390

 Score =  117 bits (292), Expect = 2e-25
 Identities = 116/419 (27%), Positives = 177/419 (42%), Gaps = 54/419 (12%)

Query: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRV 1088
            CS+C +A P   C WC     +CV  E C         C  P I+ V P + P++GGTR+
Sbjct: 526  CSQCLSAPPFVQCGWCHD---KCVRSEECLSGTWTQQIC-LPAIYKVFPNSAPLEGGTRL 581

Query: 1089 TIRGSNLGQHVQDVLGM----VTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVE 1144
            TI G + G    +   +    V +    C +   E    ++L C  G +  +    + + 
Sbjct: 582  TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSE-STMNTLKCTVGPAMNKHFNMSIII 640

Query: 1145 VPGRGRGVSEHD-FAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQP 1203
                G G +++  F+Y DP + SI P  GP AGGT LTL G+ L +G    I   +G + 
Sbjct: 641  --SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHIS--IGGKT 696

Query: 1204 CHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSF 1263
            C  L    +  L C T  +       V +      R  +   F Y  DP +    PTKSF
Sbjct: 697  C-TLKSVSNSILECYTPAQTISTEFAVKLKIDLANR--ETSIFSYREDPIVYEIHPTKSF 753

Query: 1264 LSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQF 1323
            +SGG  I   G+NL+ V  PR+ + V           GR   V    AC           
Sbjct: 754  ISGGSTITGVGKNLNSVSVPRMVINV--------HEAGRNFTV----ACQ---------- 791

Query: 1324 EEPCHVNSSQLITCRTPALPGLPEDPWVRVE--FILDNLVFDFATLNPTPFSYEADPTLQ 1381
                H ++S++I C TP+L  L     ++ +  F+LD ++  +  L      Y  +P  +
Sbjct: 792  ----HRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDL-----IYVHNPVFK 842

Query: 1382 PLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
            P   E P M       +V  ++G ++D    K EV+  +G+  C    L    + C  P
Sbjct: 843  PF--EKPVM-ISMGNENVLEIKGNDIDPEAVKGEVL-KVGNKSCENIHLHSEAVLCTVP 897



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 131/545 (24%), Positives = 215/545 (39%), Gaps = 116/545 (21%)

Query: 47  LYLGATNFLFQLSP-GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPT-----NNPNQL 100
           ++LGATN+++ L+   LQ  A   TGPVL+  DC P    D   +A  +     +N N  
Sbjct: 62  IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP--CQDCSSKANLSGGVWKDNINMA 119

Query: 101 LLVSP---GALVVCGSVHQGVCEQRRLGQLEQLLLRPE-----RPGDTQYVAANDPAVST 152
           L+V       L+ CGSV++G C++          ++ E      P   +     D  VS 
Sbjct: 120 LVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSA 179

Query: 153 VGLVAQGLAGEPLL--FVGRGYTSRGVGGG-IPPITTRALWPPDPQAAFSYEETAKLAVG 209
           +G        +  +  FVG    S       +  I+ R L        F  +++    + 
Sbjct: 180 LGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLP 239

Query: 210 RLSE-YSHHFVSAFARGASAYFLFLRRD-LQAQSRAFRAYVSRVCLRDQHYYSYVELPLA 267
              + Y   +V AF      YFL ++R+ L AQ+  F   + R C  +   +SY+E+PL 
Sbjct: 240 EFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQT--FHTRIIRFCSINSGLHSYMEMPLE 297

Query: 268 C-----------EGGRYGLIQAAAVAT-----SREVA---HGEVLFAAFSSAAPPTVGRP 308
           C           +   + ++QAA V+      +R++    + ++LF  F+ + P +    
Sbjct: 298 CILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDS---- 353

Query: 309 PSAAAGASGASALCAFPLDEVDRLANR----------------TRDACYTREG-RAEDGT 351
               A     SA+CAFP+  V+   N+                  + C+ R   R   G 
Sbjct: 354 ----AEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGC 409

Query: 352 EVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVT 411
           E    EY      A   VD                            ++  + LT+++  
Sbjct: 410 EARRDEYRTEFTTALQRVDLFMG------------------------QFSEVLLTSISTF 445

Query: 412 MEDGHTIAFLGDSQGQLHRVYL---GPGS-------DGHPYSTQSIQQGSAVSRDLTFDG 461
           ++   TIA LG S+G+  +V +   GP +       D HP S + I     V   L  +G
Sbjct: 446 IKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVI-----VEHTLNQNG 500

Query: 462 TFEHLYVMTQSTLLKVPV--ASCAQHLDCASCLAHRDPY--CGWCVLLGRCSRRSECSRG 517
              +  V+T   + K+P+    C     C+ CL+   P+  CGWC    +C R  EC  G
Sbjct: 501 ---YTLVITGKKITKIPLNGLGCRHFQSCSQCLS-APPFVQCGWC--HDKCVRSEECLSG 554

Query: 518 QGPEQ 522
              +Q
Sbjct: 555 TWTQQ 559


>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
          Length = 1408

 Score =  105 bits (263), Expect = 4e-22
 Identities = 116/437 (26%), Positives = 177/437 (40%), Gaps = 72/437 (16%)

Query: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRV 1088
            CS+C +A P   C WC     +CV  E C         C  P I+ V P + P++GGTR+
Sbjct: 526  CSQCLSAPPFVQCGWCHD---KCVRSEECLSGTWTQQIC-LPAIYKVFPNSAPLEGGTRL 581

Query: 1089 TIRGSNLGQHVQDVLGM----VTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVE 1144
            TI G + G    +   +    V +    C +   E    ++L C  G +  +    + + 
Sbjct: 582  TICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSE-STMNTLKCTVGPAMNKHFNMSIII 640

Query: 1145 VPGRGRGVSEHD-FAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQP 1203
                G G +++  F+Y DP + SI P  GP AGGT LTL G+ L +G    I   +G + 
Sbjct: 641  --SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHIS--IGGKT 696

Query: 1204 CHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTKSF 1263
            C  L    +  L C T  +       V +      R  +   F Y  DP +    PTKSF
Sbjct: 697  C-TLKSVSNSILECYTPAQTISTEFAVKLKIDLANR--ETSIFSYREDPIVYEIHPTKSF 753

Query: 1264 L------------------SGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRR 1305
            +                  SGG  I   G+NL+ V  PR+ + V           GR   
Sbjct: 754  ISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINV--------HEAGRNFT 805

Query: 1306 VVPETACSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVE--FILDNLVFD 1363
            V    AC               H ++S++I C TP+L  L     ++ +  F+LD ++  
Sbjct: 806  V----ACQ--------------HRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSK 847

Query: 1364 FATLNPTPFSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDG 1423
            +  L      Y  +P  +P   E P M       +V  ++G ++D    K EV+  +G+ 
Sbjct: 848  YFDL-----IYVHNPVFKPF--EKPVM-ISMGNENVLEIKGNDIDPEAVKGEVL-KVGNK 898

Query: 1424 PCVVKTLTRHHLYCEPP 1440
             C    L    + C  P
Sbjct: 899  SCENIHLHSEAVLCTVP 915



 Score = 88.2 bits (217), Expect = 8e-17
 Identities = 131/545 (24%), Positives = 215/545 (39%), Gaps = 116/545 (21%)

Query: 47  LYLGATNFLFQLSP-GLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPT-----NNPNQL 100
           ++LGATN+++ L+   LQ  A   TGPVL+  DC P    D   +A  +     +N N  
Sbjct: 62  IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP--CQDCSSKANLSGGVWKDNINMA 119

Query: 101 LLVSP---GALVVCGSVHQGVCEQRRLGQLEQLLLRPE-----RPGDTQYVAANDPAVST 152
           L+V       L+ CGSV++G C++          ++ E      P   +     D  VS 
Sbjct: 120 LVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSA 179

Query: 153 VGLVAQGLAGEPLL--FVGRGYTSRGVGGG-IPPITTRALWPPDPQAAFSYEETAKLAVG 209
           +G        +  +  FVG    S       +  I+ R L        F  +++    + 
Sbjct: 180 LGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLP 239

Query: 210 RLSE-YSHHFVSAFARGASAYFLFLRRD-LQAQSRAFRAYVSRVCLRDQHYYSYVELPLA 267
              + Y   +V AF      YFL ++R+ L AQ+  F   + R C  +   +SY+E+PL 
Sbjct: 240 EFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQT--FHTRIIRFCSINSGLHSYMEMPLE 297

Query: 268 C-----------EGGRYGLIQAAAVAT-----SREVA---HGEVLFAAFSSAAPPTVGRP 308
           C           +   + ++QAA V+      +R++    + ++LF  F+ + P +    
Sbjct: 298 CILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDS---- 353

Query: 309 PSAAAGASGASALCAFPLDEVDRLANR----------------TRDACYTREG-RAEDGT 351
               A     SA+CAFP+  V+   N+                  + C+ R   R   G 
Sbjct: 354 ----AEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGC 409

Query: 352 EVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVT 411
           E    EY      A   VD                            ++  + LT+++  
Sbjct: 410 EARRDEYRTEFTTALQRVDLFMG------------------------QFSEVLLTSISTF 445

Query: 412 MEDGHTIAFLGDSQGQLHRVYL---GPGS-------DGHPYSTQSIQQGSAVSRDLTFDG 461
           ++   TIA LG S+G+  +V +   GP +       D HP S + I     V   L  +G
Sbjct: 446 IKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVI-----VEHTLNQNG 500

Query: 462 TFEHLYVMTQSTLLKVPV--ASCAQHLDCASCLAHRDPY--CGWCVLLGRCSRRSECSRG 517
              +  V+T   + K+P+    C     C+ CL+   P+  CGWC    +C R  EC  G
Sbjct: 501 ---YTLVITGKKITKIPLNGLGCRHFQSCSQCLS-APPFVQCGWC--HDKCVRSEECLSG 554

Query: 518 QGPEQ 522
              +Q
Sbjct: 555 TWTQQ 559


>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
            sapiens]
          Length = 1400

 Score = 84.7 bits (208), Expect = 9e-16
 Identities = 77/272 (28%), Positives = 110/272 (40%), Gaps = 34/272 (12%)

Query: 1029 CSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRV 1088
            C RC  A    GC WC      C  ++ C         CP P +    P +GP+ G TR+
Sbjct: 533  CGRCLRAWHFMGCGWCGN---MCGQQKEC-PGSWQQDHCP-PKLTEFHPHSGPLRGSTRL 587

Query: 1089 TIRGSNLGQH----VQDVLGMVTVAGVPCAVDAQEY---------EVSSSLVCITGASGE 1135
            T+ GSN   H    V +    VTV   PC    ++          +      C     G 
Sbjct: 588  TLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFECELEPLGT 647

Query: 1136 EVAGATAVEVPGRGRGVSEH----------DFAYQDPKVHSIFPARGPRAGGTRLTLNGS 1185
            +  G T V +        +H           F++ +P + ++ P  GPRAGGT LTL G 
Sbjct: 648  QAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCLTLEGQ 707

Query: 1186 KLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQ 1245
             L  G      V+V    C LL      QL C T P  T A++P+++  G  +       
Sbjct: 708  SLSVGTSR--AVLVNGTEC-LLARVSEGQLLCATPPGATVASVPLSLQVGGAQVP-GSWT 763

Query: 1246 FKYTLDPNITSAGPTKSFLSGGREICVRGQNL 1277
            F+Y  DP + S  P   +++    IC  GQ+L
Sbjct: 764  FQYREDPVVLSISPNCGYINSHITIC--GQHL 793



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 148/584 (25%), Positives = 218/584 (37%), Gaps = 90/584 (15%)

Query: 41  DPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQL 100
           D     +++   N L  L P L+   +++TGP  D   C         P   P +   ++
Sbjct: 64  DRNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGDP-GCQTCAACGPGPHGPPGDTDTKV 122

Query: 101 LLVSPG--ALVVCGSVHQGVCEQRRL---GQLEQLLL-------RPERPGDTQYVAANDP 148
           L++ P   ALV CGS  QG C    L   G    L            RP D     A+ P
Sbjct: 123 LVLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDCPDCVAS-P 181

Query: 149 AVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGGIPP--ITTRALWPPDPQAAFSYEETAKL 206
             + V +V QG A     F         V     P  ++ R L       A  +   + L
Sbjct: 182 LGTRVTVVEQGQAS---YFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVALSVL 238

Query: 207 AVGRLSEYSHHFVSAFARGASAYFLFLR-RDLQAQSRAFRAYVSRVCLRDQHYYSYVELP 265
               L  YS  +V +F  GA  YFL ++   +     A    ++R+   +     Y EL 
Sbjct: 239 PK-HLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPELGDYRELV 297

Query: 266 LAC------------EGGR-YGLIQAA-------AVATSREVAHG-EVLFAAFSSAAPPT 304
           L C            EGG+ Y +++ A        +AT   +A G EVLF  F +     
Sbjct: 298 LDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVFVTGKDGG 357

Query: 305 VGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDVNSDC 364
            G  P+        S +CAFP+D +D L +   + C   E     G       +   S C
Sbjct: 358 PGVGPN--------SVVCAFPIDLLDTLIDEGVERCC--ESPVHPGLRRGLDFFQSPSFC 407

Query: 365 AQLPVDTLDAYPCGSDHTP---SPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFL 421
              P     +      H P   S   SRV L    +     +Q+TA+ VT  D  T+A +
Sbjct: 408 PNPPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLL---GPVQVTALYVTRLDNVTVAHM 464

Query: 422 GDSQGQLHRVYLGPGSDGHPY-STQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPV 479
           G   G++ +V L    +   Y S  S+   G  V RD++  G  +HL   +   + +VP+
Sbjct: 465 GTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVSRLG--DHLLFASGDQVFQVPI 522

Query: 480 --ASCAQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQW--------LWSFQ 528
               C   L C  CL A     CGWC     C ++ EC     P  W        L  F 
Sbjct: 523 QGPGCRHFLTCGRCLRAWHFMGCGWCG--NMCGQQKEC-----PGSWQQDHCPPKLTEFH 575

Query: 529 PELGCLQVAA----------MSPANISREETREVFLSVPDLPPL 562
           P  G L+ +           + P+ +  E T +V +      PL
Sbjct: 576 PHSGPLRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPL 619


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 67/226 (29%), Positives = 94/226 (41%), Gaps = 34/226 (15%)

Query: 684  PPARGGPSP---SPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWG--- 737
            PP +G P+    +PP+    LATP+P       GAP+T  A+  SP    +  SP G   
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPK------GAPTTPAATPPSPKGGLATPSPKGAPT 1219

Query: 738  -----PWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDL---LA 789
                 P +  G +++P   G+P     +PPSP+ GP T  P      P+ATP  L   LA
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279

Query: 790  SPL---SPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREG 846
            +P    +P+     PP+  G  A  P      PPA  P +   G+ G+  P       +G
Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP-KGSPGTPPP-------KG 1331

Query: 847  GELPEA---DEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPS 889
               P A       G      +T +   G    +  EGP  P   PS
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 68/239 (28%), Positives = 96/239 (40%), Gaps = 37/239 (15%)

Query: 668  AGPMVASHQSPLVSPDPPARGGPS-PSPPTAPKALATPAPD-----TLPVEPGAPSTATA 721
            A P +    +P  +  P  +GGP+ PSP  AP   A   P        P   GAP+T  A
Sbjct: 1072 ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131

Query: 722  SDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPS 781
            +  SP                G +++P   G+P     +PPSP+ G  T  P      P+
Sbjct: 1132 TPPSP---------------KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176

Query: 782  AT---PEDLLASPL---SPSEVAAVPP------ADPGPEALHPTVPLDLPPATVPATTFP 829
            AT   P+  LA+P    +P+  AA PP      A P P+   PT P   PP+       P
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA-PTTPAATPPSPKGGLATP 1235

Query: 830  GAMGS-VKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLIL 887
               G+   PA    + +GG  P      G   P  +T   L G   +   +G P P ++
Sbjct: 1236 SPKGAPTTPAATPPSPKGG--PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292



 Score = 71.6 bits (174), Expect = 8e-12
 Identities = 74/233 (31%), Positives = 94/233 (40%), Gaps = 34/233 (14%)

Query: 681  SPDPPA-RGGPSPSP--PTAPKALATPAPDT-------LPVEPGAPSTATASDISPGASP 730
            SP PP+ +G P+PS   P +PK +  P  +T       LP     P+T      +P  S 
Sbjct: 855  SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ-APALSM 913

Query: 731  SLLSPW---GPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDL 787
            +  SP       A  G  +SP   G+P     +PPSP+ GP T  P      P+ATP   
Sbjct: 914  TSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP 973

Query: 788  LASPLSPS------EVAAVPPADPGPEALHPTVPLDLPPATVP--------ATTFPGAMG 833
               P +PS        AA PP+  G  A         PPA  P        AT FP    
Sbjct: 974  KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG-A 1032

Query: 834  SVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSA--ELEGPPAP 884
            S  PA    + +G   P A     G AP    +TL S  G  A   L+G P P
Sbjct: 1033 STPPAATPPSPKGS--PAATPLPKG-APTTPAATLPSPKGGPATPSLKGAPTP 1082



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 61/201 (30%), Positives = 83/201 (41%), Gaps = 37/201 (18%)

Query: 670  PMVASHQSPLVSPDPPA-RGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGA 728
            P  A+  SP   P  P+ +G P+P   T P    +PA    P   GA +   A+  SP  
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA--ATPFPKGASTPPAATPPSPKG 1045

Query: 729  SPSLL-----SPWGPWA----GSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFR 779
            SP+       +P  P A      G  ++P   G+P     +PPSP+ GP T  P      
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP 1105

Query: 780  PSAT---PEDLLASPL---SPSEVAAVPPADPG-----PEALHPTVPLDLPPA------- 821
            P+AT   P+  LA+P    +P+  AA PP+  G     P    PT P   PP+       
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165

Query: 822  -------TVPATTFPGAMGSV 835
                   T PA T P   G +
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGL 1186



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 69/230 (30%), Positives = 87/230 (37%), Gaps = 35/230 (15%)

Query: 684  PPARGGPSPSP----PTAPKALATPAPDTLPVEPGAPSTATASDISPGASPS-LLSPWGP 738
            PPA   PSP      PT  +A ATP+      E  +P   T S      SP  LL P   
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSK----EASSPPAVTPSTYKGAPSPKELLIP--- 1602

Query: 739  WAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEV- 797
                 +++SP    +P     +PPSP+ GP T  P  T   P  TP  L  SP SP+ V 
Sbjct: 1603 ----PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVT 1658

Query: 798  ----AAVP------PADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGG 847
                A VP      PA  GP AL   +    P +T P  T P   G         +    
Sbjct: 1659 CKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST-PIITAPTRKGPQTKKSSATSPPIC 1717

Query: 848  ELPEADEWTGGDAPAFSTSTLLSGDGDSAEL-------EGPPAPLILPSS 890
              P A   + G     + + LL    DS++          P  PL  P S
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPES 1767



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 57/181 (31%), Positives = 77/181 (42%), Gaps = 28/181 (15%)

Query: 672  VASHQSPLVSPDPPA------RGGP-SPSPPTA--PKALATPAPDTLPVEP---GAPSTA 719
            + +  SP  +P PPA      +GGP +PSP  A  P A   P+P   P  P   GAP+  
Sbjct: 930  IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989

Query: 720  TASDISPGASPSLLSPWG--------PWAGSGS-ISSPGSTGSPLHEEPSPPSPQNGP-G 769
             A+  SP   P+  SP G        P +  GS  ++P   G+      +PPSP+  P  
Sbjct: 990  AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049

Query: 770  TAVPAPTDFRPSATPEDLLASPLSPS------EVAAVPPADPGPEALHPTVPLDLPPATV 823
            T +P      P+AT       P +PS        AA PP+  G  A        +PPA  
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT 1109

Query: 824  P 824
            P
Sbjct: 1110 P 1110



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 53/212 (25%), Positives = 72/212 (33%), Gaps = 43/212 (20%)

Query: 680  VSPDPPARGGPSPS---PPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPW 736
            +   P  +G P+P    PP+     ATP+P   P  P A                     
Sbjct: 930  IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT-------------------- 969

Query: 737  GPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSP-- 794
             P +  G  ++P   G+P     +PPSP+ GP T  P      P+ TP     SP +   
Sbjct: 970  -PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028

Query: 795  SEVAAVPPA--DPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEA 852
             + A+ PPA   P P+      PL     T PA T P   G                P  
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---------------PAT 1073

Query: 853  DEWTGGDAPAFSTSTLLSGDGDSAELEGPPAP 884
                G   P  +T     G   +   +G P P
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMP 1105



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 69/242 (28%), Positives = 95/242 (39%), Gaps = 45/242 (18%)

Query: 677  SPLVSPDPPARGGPSPSPPTA---PKALATPAPDTLPVEP---GAPSTATASDISPGASP 730
            +P V   P  +GGP+ SPP     P A   P+P   P  P   GAP+    +  SP  +P
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347

Query: 731  SL-----LSPWGPWAGSGS------ISSPGSTGSPLHEEPSP------PSPQNGPGTAVP 773
            +L      S  GP   S         ++P   G P    PSP      PSP+  P +  P
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS--P 1405

Query: 774  APTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATV-----PATTF 828
            A     P   P    A+P++    A     D  P A+ P V L   PAT      PAT  
Sbjct: 1406 AVIPLSPKKAP----ATPVTREGAATPSKGDLTPPAVTP-VSLKKAPATSAPKGGPAT-- 1458

Query: 829  PGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILP 888
            P + G   P L  +T    + P A +         ++S+        A +  P  P ++P
Sbjct: 1459 PSSKGD--PTLPAVTPPSPKEPPAPKQVA------TSSSPKKAPATPAPMGAPTLPAVIP 1510

Query: 889  SS 890
            SS
Sbjct: 1511 SS 1512



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 71/253 (28%), Positives = 91/253 (35%), Gaps = 37/253 (14%)

Query: 665  SCDAGPMVASHQSPLVSPDPPA-----RGGPSPSPPTAPKALATPAPDTLPVEPG----- 714
            S   GP   S +     P PPA     +GGP+ +PP+  +  A P+P   P  P      
Sbjct: 1355 SSKGGPTTPSSKE---GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411

Query: 715  ---APST-------ATAS--DISPGASP--SLLSPWGPWAGSGSISSPGSTGSPLHEEPS 760
               AP+T       AT S  D++P A    SL       A  G  ++P S G P     +
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471

Query: 761  PPSPQNGPG--------TAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHP 812
            PPSP+  P         +   AP    P   P      P SP EV A P +   P A   
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531

Query: 813  TVPLDLPPATV--PATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLS 870
            T+     PAT+       P AM    P          E P         +P   T +   
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591

Query: 871  GDGDSAELEGPPA 883
            G     EL  PPA
Sbjct: 1592 GAPSPKELLIPPA 1604



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 65/242 (26%), Positives = 91/242 (37%), Gaps = 31/242 (12%)

Query: 670  PMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPG-APSTATASDISPGA 728
            P   +  SP  +P PPA      +PP+  K  ATPAP   P  P   PS+   S  SP +
Sbjct: 1602 PPAVTSPSPKEAPTPPAV-----TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656

Query: 729  SPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLL 788
                +    P A  G  +  G T   L E    P+P++ P   + APT   P        
Sbjct: 1657 VTCKMGATVPQASKGLPAKKGPTA--LKEVLVAPAPESTP--IITAPTRKGPQTKKSSAT 1712

Query: 789  ASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGE 848
            + P+ P   A       GP +     PL LP     + T  G   S  P         G 
Sbjct: 1713 SPPICPDPSA--KNGSKGPLSTVAPAPL-LPVQKDSSKTAKGKDASHSPK--------GP 1761

Query: 849  L--PEADEWTGGDAPAF-------STSTLLSGDGDSAELEGPPAPL-ILPSSLDYQYDTP 898
            L  PE+   T   A AF        ++++ +       L   P+P+  LP    +   +P
Sbjct: 1762 LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSP 1821

Query: 899  GL 900
            GL
Sbjct: 1822 GL 1823



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 45/154 (29%), Positives = 62/154 (40%), Gaps = 16/154 (10%)

Query: 670  PMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPD-TLPVEPGAPSTATASDISPGA 728
            P   +  SP  +P  PA    S   PT P +   P P    P   G P+       SP  
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP---SPKR 1391

Query: 729  SPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSA-TPEDL 787
             P++ SP       G  +SP     PL  + +P +P    G A P+  D  P A TP  L
Sbjct: 1392 GPAIPSP------KGDPTSPAVI--PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443

Query: 788  LASPLSPSEVAAVPPADPGPEALHPTVPLDLPPA 821
              +P + +      PA P  +   PT+P   PP+
Sbjct: 1444 KKAPATSAPKGG--PATPSSKG-DPTLPAVTPPS 1474



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 44/150 (29%), Positives = 60/150 (40%), Gaps = 32/150 (21%)

Query: 673  ASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSL 732
            +S  SP + PDP A+ G        P +   PAP  LPV+  +  TA   D S       
Sbjct: 1709 SSATSPPICPDPSAKNGSK-----GPLSTVAPAP-LLPVQKDSSKTAKGKDASH------ 1756

Query: 733  LSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPL 792
             SP GP A   S +S   T +   +              +P P     SA P   ++ PL
Sbjct: 1757 -SPKGPLAPPESKASTPLTAAAFEK-------------VLPKPESASVSAAPSPPVSLPL 1802

Query: 793  SPSEVAAVP------PADPGPEALHPTVPL 816
            +PS V  +P      P+ PG     P+ PL
Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVLESPSKPL 1832



 Score = 45.4 bits (106), Expect = 6e-04
 Identities = 54/204 (26%), Positives = 73/204 (35%), Gaps = 32/204 (15%)

Query: 683 DPPARGGPSPSPPTA--PKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWA 740
           D P+  G S SP T   P    +  PDT       P    +S +SP  +  L  P    +
Sbjct: 792 DSPSPLGVSVSPQTKRPPTKKGSAGPDT-------PIGNLSSPVSPVEASFL--PENSLS 842

Query: 741 GSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAV 800
             GS  SP +T S     P+PPSP+  P           PSA       +PLSP  V   
Sbjct: 843 FQGSKDSPATTHS-----PTPPSPKGAP----------TPSA------VTPLSPKGVTLP 881

Query: 801 PPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDA 860
           P   P P  ++   P + P    P      +M S  P     T     +P +    G   
Sbjct: 882 PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT 941

Query: 861 PAFSTSTLLSGDGDSAELEGPPAP 884
           P  +T     G   +   +  P P
Sbjct: 942 PPAATPPSPKGGPATPSPKWAPTP 965



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 68/236 (28%), Positives = 91/236 (38%), Gaps = 24/236 (10%)

Query: 673 ASHQSPLVSPDPPARGGPSPS---PPTAPKALATPAPDTLPVEPGAPST---ATASDISP 726
           AS   P V+P P     P  +    P  PK++ +P+       PG       +  S ++P
Sbjct: 704 ASENCP-VAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762

Query: 727 GASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSA---T 783
            AS     P      S + SS G T + L + PSP      P T  P PT  + SA   T
Sbjct: 763 VASSPKECPTEDSGASATASSKG-TLTYLADSPSPLGVSVSPQTKRP-PTK-KGSAGPDT 819

Query: 784 PEDLLASPLSPSEVAAVPP-------ADPGPEALH-PTVPLDLPPATVPATTFPGAMGSV 835
           P   L+SP+SP E + +P        +   P   H PT P      T  A T     G  
Sbjct: 820 PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879

Query: 836 KPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDS-AELEGPPAPLILPSS 890
            P  +  T     LP   E  G   PA   +  LS    S  +    PAP  +P+S
Sbjct: 880 LPPKETPTPSVVNLPFPKE--GPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 51/223 (22%), Positives = 89/223 (39%), Gaps = 18/223 (8%)

Query: 688 GGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWAGSGSIS- 746
           G  + + P   + L  P  +T  +   +  + TA+   PG  P+L  P  P      +S 
Sbjct: 3   GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLSA 60

Query: 747 ----SPGSTGSPLHEEP-SPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVA--- 798
               SP  + S +   P   P PQ+  GTA+P  T         +L+  P+SP+ +A   
Sbjct: 61  ANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS 120

Query: 799 --AVPPADPGPEALHPTVPLDLPPATV-PATTFPGAMGSVKPALDWLTREGGELPEADEW 855
               P     P +  P   + L P +V  ++ FP  + +  P++     E G +      
Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSV--AVAESGSVITLSAP 178

Query: 856 TGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTP 898
                P  + + + S    +   +G P+P  + S++ Y   TP
Sbjct: 179 IAPSEPKTNLNKVPSEVVPNP--KGTPSPPCIVSTVPYHCVTP 219



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 41/160 (25%), Positives = 54/160 (33%), Gaps = 33/160 (20%)

Query: 661 THKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT 720
           T+  +  A P      +  VSP P + G  S   PT+P AL        PV P  PST  
Sbjct: 444 TNPCTIAAAPTTTFEVATCVSP-PMSSGPISNIEPTSPAALVMA-----PVAPKEPSTQV 497

Query: 721 ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTA-VPAPTDFR 779
           A+ +    SP L                          P P   +N P +  V  PT   
Sbjct: 498 ATTLRIPVSPPL--------------------------PDPEDLKNLPSSVLVKFPTQKD 531

Query: 780 PSATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLP 819
               P  L  +P SP++       DP    L    P + P
Sbjct: 532 LQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSP 571



 Score = 32.7 bits (73), Expect = 3.9
 Identities = 66/274 (24%), Positives = 98/274 (35%), Gaps = 60/274 (21%)

Query: 669 GPMVASHQSPLVSP--DPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISP 726
           GP ++     L SP   P  +G PS S P A  AL             AP +   S   P
Sbjct: 108 GPPISPAALALASPMIAPTLKGTPSSSAPLALVAL-------------APHSVQKSSAFP 154

Query: 727 GASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPED 786
              P+LL            +SP          PS    ++G    + AP    PS    +
Sbjct: 155 ---PNLL------------TSP----------PSVAVAESGSVITLSAP--IAPSEPKTN 187

Query: 787 LLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREG 846
           L      PSEV   P   P P  +  TVP        P  +    + S+ P     T   
Sbjct: 188 L---NKVPSEVVPNPKGTPSPPCIVSTVPYH---CVTPMASIQSGVASL-PQTTPTTTLA 240

Query: 847 GELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGLWELEEA 906
              P+  + T       S+  +   +  S  L+GP +P   P++L     +  +    + 
Sbjct: 241 IASPQVKDTT------ISSVLISPQNPGSLSLKGPVSP---PAALSLSTQSLPVVTSSQK 291

Query: 907 TLGASSCPCVESVQGSTLMPVHVER--EIRLLGR 938
           T G ++ P      GS L P+H      ++LLG+
Sbjct: 292 TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQ 325



 Score = 32.0 bits (71), Expect = 6.7
 Identities = 39/154 (25%), Positives = 57/154 (37%), Gaps = 5/154 (3%)

Query: 685 PARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSL-LSPWGPWAGSG 743
           PA    +P  P          P  LP+   AP  + +   S  +SP + LSP    A   
Sbjct: 536 PASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQ-STSSSPEIPLSPEATLAKK- 593

Query: 744 SISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPA 803
           S+  P   G P     SP    N   + +   +   P +    L +S ++P+ VAA P  
Sbjct: 594 SLGEPLPIGKPASSMTSPLGV-NSSASVIKTDSYAGPDSAGPLLKSSLITPT-VAAFPLE 651

Query: 804 DPGPEALHPTVPLDLPPATVPATTFPGAMGSVKP 837
              P  + PT        T  A+ F     S+ P
Sbjct: 652 SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAP 685



 Score = 31.6 bits (70), Expect = 8.7
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 13/137 (9%)

Query: 681  SPDPPARG--GPSPSPPTAPKALATPAPDTLPVE-PGAP-STATASDISPGASPSLLSPW 736
            +P PP      PSP P   PK    P+   L +E P  P + A   ++ P   P  +S  
Sbjct: 1793 APSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGG 1852

Query: 737  GPWAG-SGSISSPGSTGSPLHEEPSP----PSPQNGPGTAVPAPTDFR-PSATPEDLLAS 790
             P+     ++ +P S G P+   P+P    P  +N  G+   + +D   P    +D   +
Sbjct: 1853 VPFQSVLVNMPTPKSAGIPV---PTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQA 1909

Query: 791  PLSPSEVAAVPPADPGP 807
                +++AA    D  P
Sbjct: 1910 TTQQAQLAAAAEIDEEP 1926


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 74/234 (31%), Positives = 96/234 (41%), Gaps = 27/234 (11%)

Query: 660 CTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTA 719
           C+H +  +       H    VSP PP+   P   PPT P       P +LP EP + S A
Sbjct: 121 CSHSSPGEGASPQMFHT---VSPGPPSARPPCRVPPTTP---LNGGPGSLPPEPPSVSQA 174

Query: 720 TASDISPGA--SPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPT- 776
             +   PG    P L  P      SG  SSP          P+PP P   P  ++ AP+ 
Sbjct: 175 FPTLAGPGGLFPPRLADP----VPSGGSSSPRFLPRGNAPSPAPPPP---PAISLNAPSY 227

Query: 777 ----DFRPSATPEDLLASPLSPSEVAAVPPADPGP-EALHPTVPLDLPPAT-VPATTFPG 830
                 R S  P DL  SP +P   ++ PP+DP          P  LPP+  +PA   P 
Sbjct: 228 NWGAALRSSLVPSDL-GSPPAP-HASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPA 285

Query: 831 AMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAP 884
           +   V  A   L    G L  A    G  AP F  S+LLS    +A+ + PP P
Sbjct: 286 SQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSA---AAKAQHPPLP 336



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 57/211 (27%), Positives = 76/211 (36%), Gaps = 22/211 (10%)

Query: 678 PLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWG 737
           P   P PP   G    P     +L  P P  L   P AP +   +   P      L   G
Sbjct: 579 PPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLP------LLALG 632

Query: 738 PWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEV 797
           P AG G  S+ G+ G         PS +   G    +P  F P + P  L+A   +    
Sbjct: 633 PTAGDGEGSAEGAGG---------PSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAA 683

Query: 798 AAVPPADPGPEALHPTVPLDLPP--ATVPATTFPGAMGSVKPALDWLTREGGELPEADEW 855
              PP+   P+    + P   PP  +   ATT PGA      +L       G  P+    
Sbjct: 684 TLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGA-----SSLGKAPSNSGRPPQLLSP 738

Query: 856 TGGDAPAFSTSTLLSGDGDSAELEGPPAPLI 886
             G +     S+L S  G    L  PP PL+
Sbjct: 739 LLGASLLGDLSSLTSSPGALPSLLQPPGPLL 769



 Score = 45.4 bits (106), Expect = 6e-04
 Identities = 50/164 (30%), Positives = 56/164 (34%), Gaps = 31/164 (18%)

Query: 682 PDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGPWAG 741
           P P     P P PPT+    AT        +PGA S   A   S G  P LLSP    + 
Sbjct: 693 PQPCVLSAPQPGPPTSSVTTAT-------TDPGASSLGKAPSNS-GRPPQLLSPLLGASL 744

Query: 742 SGSISSPGSTGSPLHEEPSPPSP--------QNGPGTAVPAPTDFR-------------P 780
            G +SS  S+   L     PP P        Q  PG   P P                 P
Sbjct: 745 LGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIP 804

Query: 781 SATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVP 824
              PE     P SP+      PA P   AL P  P   P   VP
Sbjct: 805 PEQPEAPCLPPESPASALEPEPARPPLSALAP--PHGSPDPPVP 846



 Score = 40.4 bits (93), Expect = 0.019
 Identities = 70/240 (29%), Positives = 84/240 (35%), Gaps = 52/240 (21%)

Query: 682 PDPPARGGPSPSPPTAPKALATPAPDT--LPVEPGAPSTATASDISPGASPSLLSPWGPW 739
           P PP     SP  P  P   + P   +  L   PGAP+   AS      SP L S   P 
Sbjct: 440 PPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQS---PS 496

Query: 740 AGSGSISSPGSTGSPL-HEEPSP-PSPQNG--------PGT--AVPAPTDFRPSATPEDL 787
            G G  + P     PL   E  P PSP+ G        PG   A+P P        P  L
Sbjct: 497 EGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSL-GQPPPSPL 555

Query: 788 LASPL----------SPSEVAAVPPADPGP--------------EALHPTVPLD-LPPAT 822
           L   L           P E    PP  PGP               +L P  P D LPP +
Sbjct: 556 LNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPS 615

Query: 823 VPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPP 882
            P +     + S  P L  L    G+   + E  GG      +    SG GD + L  PP
Sbjct: 616 APPSNL---LASFLPLLA-LGPTAGDGEGSAEGAGG-----PSGEPFSGLGDLSPLLFPP 666


>gi|16306552 semaphorin Y [Homo sapiens]
          Length = 930

 Score = 68.9 bits (167), Expect = 5e-11
 Identities = 90/334 (26%), Positives = 125/334 (37%), Gaps = 68/334 (20%)

Query: 217 HFVSAFARGASAYFLFLRRDLQAQ--SRAFRAYVSRVCLRD---------QHYYSYVELP 265
           HFV A   G   YF F    ++     R   + V+RVC RD         +H+ S+++L 
Sbjct: 225 HFVQALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLR 284

Query: 266 LACE--GGRYGLIQAAAVATSREVAHGE-VLFAAFSSAAPPTVGRPPSAAAGASGASALC 322
           L C   G            T     HG   LF  F++      G            SA+C
Sbjct: 285 LNCSVPGDSTFYFDVLQALTGPVNLHGRSALFGVFTTQTNSIPG------------SAVC 332

Query: 323 AFPLDEVDR------LANRTRDACYT-----REGRAEDGTEVAYIEYDVNSDCAQLPVDT 371
           AF LDE++R         R+ D  +T     R      G+        + S    LP D 
Sbjct: 333 AFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDV 392

Query: 372 LD---AYPCGSDHTPSPMASRVPLEATPILEWPG-IQLTAVAVT-MEDGH---TIAFLGD 423
           L    A+P      P       P+   P+L       LT VAV  M   H   T+ FLG 
Sbjct: 393 LTFIKAHPLLDPAVP-------PVTHQPLLTLTSRALLTQVAVDGMAGPHSNITVMFLGS 445

Query: 424 SQGQLHRVYLGPGSDGHPY---------------STQSIQQGSAVSRDLTFDGTFEHLYV 468
           + G + +V    G  G P                S +   Q +     L  D     L+V
Sbjct: 446 NDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFV 505

Query: 469 MTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGW 501
                ++ +P++ CA+H  C  SCLA +DPYCGW
Sbjct: 506 AFSGCIVYLPLSRCARHGACQRSCLASQDPYCGW 539


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 66/239 (27%), Positives = 95/239 (39%), Gaps = 28/239 (11%)

Query: 682  PDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISP-GASPSLLSPWGPWA 740
            P  PA   P+P  PT+P A   P     P EP +P+ A  +   P   + ++ +P  P +
Sbjct: 1013 PTSPAAAVPTPEEPTSPAAAVPP-----PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067

Query: 741  GSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAV 800
             + ++ +P    SP    P+P  P   P  AVP P +     +P   + +P  P+  AA 
Sbjct: 1068 PAAAVPTPEEPTSPAAAVPTPEEP-TSPAAAVPTPEE---PTSPAAAVPTPEEPASPAAA 1123

Query: 801  PPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDA 860
             P    P +    VP    PA  PA   P    S   A+   T E    P A   T  ++
Sbjct: 1124 VPTPEEPASPAAAVPTPEEPA-FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182

Query: 861  PAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPG--LWELEEATLGASSCPCVE 917
             +F+           A LE P +P            TP   +  LEE T  A+S P  E
Sbjct: 1183 ASFAAVV--------ATLEEPTSPAA-------SVPTPAAMVATLEEFTSPAASVPTSE 1226



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 66/252 (26%), Positives = 97/252 (38%), Gaps = 36/252 (14%)

Query: 678  PLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWG 737
            P   P  PA   P+P  PT+P A A P P+  P  P A         SP A  ++ +P  
Sbjct: 1035 PPEEPTSPAAAVPTPEEPTSP-AAAVPTPEE-PTSPAAAVPTPEEPTSPAA--AVPTPEE 1090

Query: 738  PWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEV 797
            P + + ++ +P    SP    P+P  P + P  AVP P +      P    A+  +P E 
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPAS-PAAAVPTPEE------PASPAAAVPTPEEP 1143

Query: 798  AAVPPADPGPE-----ALHPTVPLD--LPPATVPATTFPGAMGSVKPALDWLTREGGELP 850
            A   PA P PE     A+    P +   P A VP      +  +V   L+  T     +P
Sbjct: 1144 AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203

Query: 851  EADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGLWELEEATLGA 910
                      PA   +TL      +A +     P  L +++            EE T  A
Sbjct: 1204 ---------TPAAMVATLEEFTSPAASVPTSEEPASLAAAVS---------NPEEPTSPA 1245

Query: 911  SSCPCVESVQGS 922
            ++ P +E    S
Sbjct: 1246 AAVPTLEEPTSS 1257



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 59/236 (25%), Positives = 84/236 (35%), Gaps = 22/236 (9%)

Query: 698  PKALATPAPDT-LPVEPGAPSTATASDISPGASPSLL--SPWGPWAGSGSISSPGSTGSP 754
            P+   TPA     P EP   +   ++   P ASP+    +P  P + + ++ +P    SP
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEP-ASPAAAVPTPEEPTSPAAAVPTPEEPTSP 1029

Query: 755  LHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHPTV 814
                P P  P + P  AVP P +    A        P SP+     P     P A  PT 
Sbjct: 1030 AAAVPPPEEPTS-PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088

Query: 815  PLDLPPA---------TVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFST 865
                 PA         T PA   P       PA    T E    P A   T  + PAF  
Sbjct: 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT-PEEPAFPA 1147

Query: 866  STLLSGDGDSAELEGPPAP-------LILPSSLDYQYDTPGLWELEEATLGASSCP 914
              + + +  ++     P P         +P+  +       +  LEE T  A+S P
Sbjct: 1148 PAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 59/229 (25%), Positives = 90/229 (39%), Gaps = 36/229 (15%)

Query: 674  SHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPST------ATASDISPG 727
            S  + +  P P     P+ + PT  ++ +  A      EP +P+       A  + +   
Sbjct: 1156 SASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEF 1215

Query: 728  ASPSLLSPWG--PWAGSGSISSPGSTGSPLH-----EEPSP-------PSPQNGPGTAVP 773
             SP+   P    P + + ++S+P    SP       EEP+        P   + P  +VP
Sbjct: 1216 TSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVP 1275

Query: 774  APTDFRPSATPEDLLASPLSPS------EVAAVPPAD-PGPEALHPTVPLDLPPATVPAT 826
             P +    A     L  P SP+      EVAA+P A  P PE     VP  +P A VP  
Sbjct: 1276 TPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE-----VPA-IPAAAVPPM 1329

Query: 827  TFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDS 875
                 +G   P L  ++     +P ++E T     A ST   +  D DS
Sbjct: 1330 EEVSPIG--VPFLG-VSAHTDSVPISEEGTPVLEEASSTGMWIKEDLDS 1375



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 46/194 (23%), Positives = 70/194 (36%), Gaps = 9/194 (4%)

Query: 696  TAPKALATPAPDTLPVEPGAPSTATAS---DISPGASPSLLSP-WGPWAGSGSISSPGST 751
            +AP+    PA  T+ V  G  + A  S   + +P  + ++        AG     +  + 
Sbjct: 902  SAPERATVPAV-TVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI 960

Query: 752  GSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALH 811
              P+ EE   P     P T V AP +   +A        P SP+     P     P A  
Sbjct: 961  TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020

Query: 812  PTVPLDL-PPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLS 870
            PT      P A VP    P +  +  P  +  T     +P  +E T   +PA +  T   
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPTPEE 1077

Query: 871  GDGDSAELEGPPAP 884
                +A +  P  P
Sbjct: 1078 PTSPAAAVPTPEEP 1091


>gi|28872814 semaphorin 4G [Homo sapiens]
          Length = 843

 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 89/364 (24%), Positives = 140/364 (38%), Gaps = 64/364 (17%)

Query: 190 WPPDPQAAFSY--EETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAY 247
           W  D +  FS    E+   AVG   +  + F        S  F       Q++S    A 
Sbjct: 212 WLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFT------QSRSSHRVAR 265

Query: 248 VSRVCLRD--------QHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAAFSS 299
           V+RVC  D        + + S+++  L C    Y  ++    +   E +     +AAF+ 
Sbjct: 266 VARVCKGDLGGKKILQKKWTSFLKARLICHIPLYETLRGVC-SLDAETSSRTHFYAAFTL 324

Query: 300 AAPPTVGRPPSAAAGASGASALCAFPLDEVDRLAN----RTRDACYTREGRAEDGT---- 351
                     S       ASA+C + L E+  +        +D    R GR E G     
Sbjct: 325 ----------STQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGS-RRWGRYEGGVPEPR 373

Query: 352 -------EVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQ 404
                   +    Y+ + D   L +D +  +P  +          VP    P+L    I+
Sbjct: 374 PGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPV-------VPTRGRPLLLKRNIR 426

Query: 405 ---LTAVAVTMEDGHT--IAFLGDSQGQLHR-VYLGPGSDGHPYSTQSIQQGSAVSRDLT 458
              LT   VT   G T  + FLG + G +H+ V LG G   H      + + S    +L 
Sbjct: 427 YTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGM--HIIEETQVFRESQSVENLV 484

Query: 459 FDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGW------CVLLGRCSRRS 512
                  LYV   S ++++P++SC+++  C  C+  RDPYCGW      C      + RS
Sbjct: 485 ISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTIANRS 544

Query: 513 ECSR 516
           + SR
Sbjct: 545 QGSR 548


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 62/185 (33%), Positives = 71/185 (38%), Gaps = 17/185 (9%)

Query: 664 ASCDAGPMVASHQSPLVSPDPPARGGPSPS-----PPTAPKALATPAPDTLPVEPGAPST 718
           AS  A  +      P  +P PPA   P  S     PP AP    TP P   P  P  P  
Sbjct: 554 ASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 613

Query: 719 ATASDISPGASP--SLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGP-GTAVPAP 775
                 SP + P  + +SP  P +G  +I  P     PL E    PSP + P GTA+P P
Sbjct: 614 GGVCISSPPSLPGGTAISPPPPLSGDATIPPP----PPLPEGVGIPSPSSLPGGTAIPPP 669

Query: 776 TDFRPSATPEDLLASPLSPSEVAAVPPADPGP-EALHPTVPLDLP--PATVPATTFPGAM 832
                SA        P  P      PP  P P EA  P  P  LP  P   P   FPG  
Sbjct: 670 PPLPGSARIPP--PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727

Query: 833 GSVKP 837
           G   P
Sbjct: 728 GIPPP 732



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 19/119 (15%)

Query: 680 VSPDPPARGGPS-PSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGP 738
           +SP PP  G  + P PP  P+ +  P+P +LP     P         PG S  +  P  P
Sbjct: 630 ISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL----PG-SARIPPPPPP 684

Query: 739 WAGSGSISSP-----GSTGSPLHEEPSPPSP--------QNGPGTAVPAPTDFRPSATP 784
             GS  I  P     G  G P    P P  P          GPG   P P    P   P
Sbjct: 685 LPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 743



 Score = 38.1 bits (87), Expect = 0.093
 Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 6/102 (5%)

Query: 742 SGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVA--- 798
           + +I+ P S  S     P+PP P +  GT +P P     S TP      P  P  +    
Sbjct: 558 AAAITVPPSVPSRAPVPPAPPLPGDS-GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 616

Query: 799 --AVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPA 838
             + PP+ PG  A+ P  PL       P    P  +G   P+
Sbjct: 617 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 658



 Score = 32.3 bits (72), Expect = 5.1
 Identities = 48/195 (24%), Positives = 61/195 (31%), Gaps = 9/195 (4%)

Query: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
           ++A++S A I+   +      VP  PPL PG+S     G    P    G     P P P 
Sbjct: 552 EMASLSAAAITVPPSVPSRAPVPPAPPL-PGDS-----GTIIPPPPAPGDSTTPPPPPPP 605

Query: 595 EAPVLPR-GADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNW 653
             P  P  G   +S    L  G  +     LS    +      P        SS  G   
Sbjct: 606 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 665

Query: 654 CVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARG--GPSPSPPTAPKALATPAPDTLPV 711
                     A     P      + +  P PP  G  G  P PP  P     P P   P 
Sbjct: 666 IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG 725

Query: 712 EPGAPSTATASDISP 726
            PG P       + P
Sbjct: 726 GPGIPPPPPGMGMPP 740


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 62/185 (33%), Positives = 71/185 (38%), Gaps = 17/185 (9%)

Query: 664 ASCDAGPMVASHQSPLVSPDPPARGGPSPS-----PPTAPKALATPAPDTLPVEPGAPST 718
           AS  A  +      P  +P PPA   P  S     PP AP    TP P   P  P  P  
Sbjct: 563 ASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 622

Query: 719 ATASDISPGASP--SLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGP-GTAVPAP 775
                 SP + P  + +SP  P +G  +I  P     PL E    PSP + P GTA+P P
Sbjct: 623 GGVCISSPPSLPGGTAISPPPPLSGDATIPPP----PPLPEGVGIPSPSSLPGGTAIPPP 678

Query: 776 TDFRPSATPEDLLASPLSPSEVAAVPPADPGP-EALHPTVPLDLP--PATVPATTFPGAM 832
                SA        P  P      PP  P P EA  P  P  LP  P   P   FPG  
Sbjct: 679 PPLPGSARIPP--PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736

Query: 833 GSVKP 837
           G   P
Sbjct: 737 GIPPP 741



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 19/119 (15%)

Query: 680 VSPDPPARGGPS-PSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGASPSLLSPWGP 738
           +SP PP  G  + P PP  P+ +  P+P +LP     P         PG S  +  P  P
Sbjct: 639 ISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL----PG-SARIPPPPPP 693

Query: 739 WAGSGSISSP-----GSTGSPLHEEPSPPSP--------QNGPGTAVPAPTDFRPSATP 784
             GS  I  P     G  G P    P P  P          GPG   P P    P   P
Sbjct: 694 LPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 752



 Score = 38.1 bits (87), Expect = 0.093
 Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 6/102 (5%)

Query: 742 SGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVA--- 798
           + +I+ P S  S     P+PP P +  GT +P P     S TP      P  P  +    
Sbjct: 567 AAAITVPPSVPSRAPVPPAPPLPGDS-GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 625

Query: 799 --AVPPADPGPEALHPTVPLDLPPATVPATTFPGAMGSVKPA 838
             + PP+ PG  A+ P  PL       P    P  +G   P+
Sbjct: 626 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 667



 Score = 32.3 bits (72), Expect = 5.1
 Identities = 48/195 (24%), Positives = 61/195 (31%), Gaps = 9/195 (4%)

Query: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
           ++A++S A I+   +      VP  PPL PG+S     G    P    G     P P P 
Sbjct: 561 EMASLSAAAITVPPSVPSRAPVPPAPPL-PGDS-----GTIIPPPPAPGDSTTPPPPPPP 614

Query: 595 EAPVLPR-GADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNW 653
             P  P  G   +S    L  G  +     LS    +      P        SS  G   
Sbjct: 615 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 674

Query: 654 CVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARG--GPSPSPPTAPKALATPAPDTLPV 711
                     A     P      + +  P PP  G  G  P PP  P     P P   P 
Sbjct: 675 IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG 734

Query: 712 EPGAPSTATASDISP 726
            PG P       + P
Sbjct: 735 GPGIPPPPPGMGMPP 749


>gi|126116589 fibrocystin L [Homo sapiens]
          Length = 4243

 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 70/272 (25%), Positives = 113/272 (41%), Gaps = 21/272 (7%)

Query: 1027 GDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGT 1086
            GD  R  +  PQ   V+  G   +C      G+          PL+ ++ P  G  + GT
Sbjct: 1030 GDLLRTPSQQPQVE-VYVNGIPAKC-----SGDCGFTWDSNITPLVLAISPSQGSYEEGT 1083

Query: 1087 RVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVP 1146
             +TI GS         + +  V     +VD +E +       + G++G      +  +V 
Sbjct: 1084 ILTIVGSGFSPSSAVTVSVGPVGCSLLSVDEKELKCQ----ILNGSAGHAPVAVSMADVG 1139

Query: 1147 -GRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCH 1205
              +  G  E  F YQ    H I+P  G  AGGT LTL+G     G  E+ +V+VG++ C+
Sbjct: 1140 LAQNVGGEEFYFVYQSQISH-IWPDSGSIAGGTLLTLSG----FGFNENSKVLVGNETCN 1194

Query: 1206 LLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTL--DPNITSAGPTKSF 1263
            ++ E    ++ C T P+ T  T+ ++V     +    R  F Y     P IT   P    
Sbjct: 1195 VI-EGDLNRITCRT-PKKTEGTVDISVTTNGFQ-ATARDAFSYNCLQTPIITDFSPKVRT 1251

Query: 1264 LSGGREICVRGQNLDVVQTPRIRVTVVSRMLQ 1295
            + G   + ++G N     T  + V V  +  Q
Sbjct: 1252 ILGEVNLTIKGYNFGNELTQNMAVYVGGKTCQ 1283



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 48/182 (26%), Positives = 73/182 (40%), Gaps = 11/182 (6%)

Query: 1072 IHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG 1131
            I ++ P  G   GG  +T+ G+        +L    V G  CA+D    + ++ L  I  
Sbjct: 2001 IQNINPSQGSFGGGQTMTVTGTGFNPQNSIIL----VCGSECAIDRLRSDYTTLLCEIPS 2056

Query: 1132 ASGEEVAGATAVEVP-GRGRGVSEHDFAYQ---DPKVHSIFPARGPRAGGTRLTLNGSKL 1187
             +G     A  V V  G+    S   F Y     P + ++ P RG  AGGTRLT+ GS  
Sbjct: 2057 NNGTGAEQACEVSVVNGKDLSQSMTPFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGSG- 2115

Query: 1188 LTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWF-GATERRLQRGQF 1246
             +  +ED+ + + +  C  +       + C T         PV V   G    +L    F
Sbjct: 2116 FSENMEDVHITIAEAKCD-VEYSNKTHIICMTDAHTLSGWAPVCVHIRGVGMAKLDNADF 2174

Query: 1247 KY 1248
             Y
Sbjct: 2175 LY 2176



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 53/210 (25%), Positives = 88/210 (41%), Gaps = 21/210 (10%)

Query: 1072 IHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG 1131
            I  + P +G + GGT +T+ G    ++ + ++G  T     C V      +   L  IT 
Sbjct: 1157 ISHIWPDSGSIAGGTLLTLSGFGFNENSKVLVGNET-----CNV------IEGDLNRITC 1205

Query: 1132 ASGEEVAGATAVEVPGRGRGVSEHD-FAY---QDPKVHSIFPARGPRAGGTRLTLNGSKL 1187
             + ++  G   + V   G   +  D F+Y   Q P +    P      G   LT+ G   
Sbjct: 1206 RTPKKTEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPKVRTILGEVNLTIKGYNF 1265

Query: 1188 LTGRLEDIRVVVGDQPCHLLPEQQSEQLRC---ETSPRPTPATLPVAVWFGATERRLQRG 1244
                 +++ V VG + C +L    ++ +RC   + SP      + V  W  A+ R     
Sbjct: 1266 GNELTQNMAVYVGGKTCQILHWNFTD-IRCLLPKLSPGKHDIYVEVRNWGFASTRDKLNS 1324

Query: 1245 QFKYTLDPNITSAGPTKSFLSGGREICVRG 1274
              +Y L+  +TS  P +  L GG EI +RG
Sbjct: 1325 SIQYVLE--VTSMFPQRGSLFGGTEITIRG 1352



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 10/95 (10%)

Query: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129
            PLI +V P  G   GGTR+T+ GS   ++++DV   +T+A   C V   EY   + ++C+
Sbjct: 2091 PLITAVSPKRGSTAGGTRLTVVGSGFSENMEDV--HITIAEAKCDV---EYSNKTHIICM 2145

Query: 1130 TGASGEEVAGATAVEVPGRGRGVSE---HDFAYQD 1161
            T A    ++G   V V  RG G+++    DF Y D
Sbjct: 2146 TDA--HTLSGWAPVCVHIRGVGMAKLDNADFLYVD 2178



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 51/215 (23%), Positives = 86/215 (40%), Gaps = 20/215 (9%)

Query: 1067 CPAPLIHSVEP-LTG----PVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYE 1121
            C    + S+ P +TG     V G  +V I G  LG  ++D+   +       A++  E  
Sbjct: 1739 CTFSYLESITPYITGVFPNSVIGSVKVLIEGEGLGTVLEDIAVFIGNQQFR-AIEVNENN 1797

Query: 1122 VSSSLVCITGASGEEVAGATAVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLT 1181
            +++ +  +         G  +V V    +G++  +     P V S+ P  G   GGT L 
Sbjct: 1798 ITALVTPLP-------VGHHSVSVVVGSKGLALGNLTVSSPPVASLSPTSGSIGGGTTLV 1850

Query: 1182 LNGSKLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRL 1241
            + G+    G   +  V +GD+PC ++    +E + C T P  T   + V ++        
Sbjct: 1851 ITGNGFYPG---NTTVTIGDEPCQIISINPNE-VYCRT-PAGTTGMVDVKIFVNTI--AY 1903

Query: 1242 QRGQFKYTLDPNITSAGPTKSFLSGGREICVRGQN 1276
                F Y L+      G   S    G EI + G N
Sbjct: 1904 PPLLFTYALEDTPFLRGIIPSRGPPGTEIEITGSN 1938



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 85/367 (23%), Positives = 137/367 (37%), Gaps = 77/367 (20%)

Query: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129
            P I  V P  G   G T VTI+GS  G  V      V +   PC V +  Y   +++ C 
Sbjct: 1659 PNIDLVLPNAGSTTGMTSVTIKGS--GFAVSSAGVKVLMGHFPCKVLSVNY---TAIECE 1713

Query: 1130 TGASGEEVAGATAV--EVPGRGRGVSEHDFAYQD---PKVHSIFPARGPRAGGTRLTLNG 1184
            T  + +++     +   VP + +G     F+Y +   P +  +FP      G  ++ + G
Sbjct: 1714 TSPAAQQLVDVDLLIHGVPAQCQG--NCTFSYLESITPYITGVFP--NSVIGSVKVLIEG 1769

Query: 1185 SKLLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRG 1244
              L T  LEDI V +G+Q    + E     +    +P P      V+V  G+  + L  G
Sbjct: 1770 EGLGT-VLEDIAVFIGNQQFRAI-EVNENNITALVTPLPV-GHHSVSVVVGS--KGLALG 1824

Query: 1245 QFKYTLDPNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRR 1304
                +  P + S  PT   + GG  + + G                              
Sbjct: 1825 NLTVS-SPPVASLSPTSGSIGGGTTLVITGNGF--------------------------- 1856

Query: 1305 RVVPETACSLGPSCSSQQFEEPCHVNS--SQLITCRTPALPGLPEDPWVRVEFILDNLVF 1362
                 T  ++G        +EPC + S     + CRTPA         V V+  ++ + +
Sbjct: 1857 -YPGNTTVTIG--------DEPCQIISINPNEVYCRTPA----GTTGMVDVKIFVNTIAY 1903

Query: 1363 DFATLNPTPFSY--EADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMI 1420
                  P  F+Y  E  P L+ +      +P R  PG+   + G N    +   E+  MI
Sbjct: 1904 P-----PLLFTYALEDTPFLRGI------IPSRGPPGTEIEITGSNFGFEIL--EISVMI 1950

Query: 1421 GDGPCVV 1427
             +  C V
Sbjct: 1951 NNIQCNV 1957



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 42/190 (22%)

Query: 1070 PLIHSVEPLTGPVDGGTRVTIRG-------------SNLGQHVQDVLGMVTVAGVPCA-- 1114
            P I S+ PL+G    GT +TI+G             S+ G++V+ +   V + G+PC   
Sbjct: 146  PTIRSITPLSGTP--GTLITIQGRIFTDVYGSNIALSSNGKNVRIL--RVYIGGMPCELL 201

Query: 1115 VDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRGRG-VSEHDFAYQDPK---------- 1163
            +   +      L    G  G  V   T   +       + ++D+    P+          
Sbjct: 202  IPQSDNLYGLKLDHPNGDMGSMVCKTTGTFIGHHNVSFILDNDYGRSFPQKMAYFVSSLN 261

Query: 1164 ----------VHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGDQPCHLLPEQQSE 1213
                      V  IFP++G   GGT LT++G +        +RV+VG +PC +L   ++ 
Sbjct: 262  KIAMFQTYAEVTMIFPSQGSIRGGTTLTISG-RFFDQTDFPVRVLVGGEPCDILNVTEN- 319

Query: 1214 QLRCETSPRP 1223
             + C+T P+P
Sbjct: 320  SICCKTPPKP 329



 Score = 40.4 bits (93), Expect = 0.019
 Identities = 49/210 (23%), Positives = 83/210 (39%), Gaps = 17/210 (8%)

Query: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129
            P +  + P  GP   GT + I GSN G  + ++   V +  + C V      V   +V  
Sbjct: 1916 PFLRGIIPSRGPP--GTEIEITGSNFGFEILEI--SVMINNIQCNVTMANDSVVQCIV-- 1969

Query: 1130 TGASGEEVAGATAVEVPGRGRGVSEHDFAYQDP-KVHSIFPARGPRAGGTRLTLNGSKLL 1188
                G+   G   V +  + +G +     ++ P  + +I P++G   GG  +T+ G+   
Sbjct: 1970 ----GDHAGGTFPVMMHHKTKGSAMSTVVFEYPLNIQNINPSQGSFGGGQTMTVTGTGF- 2024

Query: 1189 TGRLEDIRVVVGDQPCHLLPEQQSEQLRCE-TSPRPTPA--TLPVAVWFGA-TERRLQRG 1244
                  I +V G +            L CE  S   T A     V+V  G    + +   
Sbjct: 2025 -NPQNSIILVCGSECAIDRLRSDYTTLLCEIPSNNGTGAEQACEVSVVNGKDLSQSMTPF 2083

Query: 1245 QFKYTLDPNITSAGPTKSFLSGGREICVRG 1274
             +  +L P IT+  P +   +GG  + V G
Sbjct: 2084 TYAVSLTPLITAVSPKRGSTAGGTRLTVVG 2113



 Score = 37.4 bits (85), Expect = 0.16
 Identities = 43/181 (23%), Positives = 72/181 (39%), Gaps = 47/181 (25%)

Query: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLG------------MVTVAGVPCAVDA 1117
            P +  + P  G ++G TR+TIRG    Q  Q   G            + +   + C V+ 
Sbjct: 31   PKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAELGNSVQLISSFQSITCDVE- 89

Query: 1118 QEYEVSSSLVCITGASGEEVAGATAVEVPGRGRGVSEHDF---------------AYQDP 1162
            ++   S+ + C T A  E+   +  V V   G  V+E++                +++ P
Sbjct: 90   KDASHSTQITCYTRAMPED---SYTVRVSVDGVPVTENNTCKGHINSWECTFNAKSFRTP 146

Query: 1163 KVHSIFPARGPRAGGTRLTLNGSKLLTG-------------RLEDIRVVVGDQPCHLLPE 1209
             + SI P  G    GT +T+ G ++ T               +  +RV +G  PC LL  
Sbjct: 147  TIRSITPLSG--TPGTLITIQG-RIFTDVYGSNIALSSNGKNVRILRVYIGGMPCELLIP 203

Query: 1210 Q 1210
            Q
Sbjct: 204  Q 204



 Score = 36.6 bits (83), Expect = 0.27
 Identities = 49/198 (24%), Positives = 76/198 (38%), Gaps = 18/198 (9%)

Query: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREA--CGEAEAVATQC-PAPLIHSVEPL 1078
            C+V  GD +R     P+      EG     VT         +A +  C   P+I    P 
Sbjct: 1193 CNVIEGDLNRITCRTPKK----TEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPK 1248

Query: 1079 TGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVA 1138
               + G   +TI+G N G  +   +  V V G  C +    +     L+        ++ 
Sbjct: 1249 VRTILGEVNLTIKGYNFGNELTQNMA-VYVGGKTCQILHWNFTDIRCLLPKLSPGKHDIY 1307

Query: 1139 GATAVEVPGRG----RGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLED 1194
                VEV   G    R        Y   +V S+FP RG   GGT +T+ G    T   E+
Sbjct: 1308 ----VEVRNWGFASTRDKLNSSIQYV-LEVTSMFPQRGSLFGGTEITIRGFGFSTIPAEN 1362

Query: 1195 IRVVVGDQPCHLLPEQQS 1212
              V++G  PC++    ++
Sbjct: 1363 -TVLLGSIPCNVTSSSEN 1379


>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
          Length = 597

 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 80/359 (22%), Positives = 138/359 (38%), Gaps = 78/359 (21%)

Query: 217 HFVSAFARGASAYFLFLRRDLQAQS--RAFRAYVSRVCLRD---------QHYYSYVELP 265
           HF+ A   G   YF F    ++  +  +A  + V+R+C  D         +H+ S+++  
Sbjct: 222 HFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKAR 281

Query: 266 LACE--GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCA 323
           L C   G  +         T     +G            PTV    +    +   SA+CA
Sbjct: 282 LNCSVPGDSFFYFDVLQSITDIIQINGI-----------PTVVGVFTTQLNSIPGSAVCA 330

Query: 324 FPLDEVDRLAN----------------------RTRDACYTREGRAEDGTEVAYIEYDVN 361
           F +D+++++                        + R  C  + G AE         Y  +
Sbjct: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE--------AYKTS 382

Query: 362 SDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG----HT 417
            D     +  + ++P      P P+A       T +      +LTA++V    G    +T
Sbjct: 383 IDFPDETLSFIKSHPLMDSAVP-PIADEPWFTKTRVR----YRLTAISVDHSAGPYQNYT 437

Query: 418 IAFLGDSQGQLHRVYL--GPGSDGHPYSTQSIQ-----QGSAVSRD------LTFDGTFE 464
           + F+G   G + +V     P S       + I+     + SA + +      L  D    
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497

Query: 465 HLYVMTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQ 522
            LYV   S ++++P++ C ++  C  SC+A RDPYCGW +  G C R +     +G EQ
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW-LSQGSCGRVTPGMLAEGYEQ 555


>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
          Length = 1073

 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 80/359 (22%), Positives = 138/359 (38%), Gaps = 78/359 (21%)

Query: 217 HFVSAFARGASAYFLFLRRDLQAQS--RAFRAYVSRVCLRD---------QHYYSYVELP 265
           HF+ A   G   YF F    ++  +  +A  + V+R+C  D         +H+ S+++  
Sbjct: 222 HFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKAR 281

Query: 266 LACE--GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCA 323
           L C   G  +         T     +G            PTV    +    +   SA+CA
Sbjct: 282 LNCSVPGDSFFYFDVLQSITDIIQINGI-----------PTVVGVFTTQLNSIPGSAVCA 330

Query: 324 FPLDEVDRLAN----------------------RTRDACYTREGRAEDGTEVAYIEYDVN 361
           F +D+++++                        + R  C  + G AE         Y  +
Sbjct: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE--------AYKTS 382

Query: 362 SDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG----HT 417
            D     +  + ++P      P P+A       T +      +LTA++V    G    +T
Sbjct: 383 IDFPDETLSFIKSHPLMDSAVP-PIADEPWFTKTRVR----YRLTAISVDHSAGPYQNYT 437

Query: 418 IAFLGDSQGQLHRVYL--GPGSDGHPYSTQSIQ-----QGSAVSRD------LTFDGTFE 464
           + F+G   G + +V     P S       + I+     + SA + +      L  D    
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497

Query: 465 HLYVMTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQ 522
            LYV   S ++++P++ C ++  C  SC+A RDPYCGW +  G C R +     +G EQ
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW-LSQGSCGRVTPGMLAEGYEQ 555


>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
          Length = 1017

 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 80/359 (22%), Positives = 138/359 (38%), Gaps = 78/359 (21%)

Query: 217 HFVSAFARGASAYFLFLRRDLQAQS--RAFRAYVSRVCLRD---------QHYYSYVELP 265
           HF+ A   G   YF F    ++  +  +A  + V+R+C  D         +H+ S+++  
Sbjct: 222 HFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKAR 281

Query: 266 LACE--GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCA 323
           L C   G  +         T     +G            PTV    +    +   SA+CA
Sbjct: 282 LNCSVPGDSFFYFDVLQSITDIIQINGI-----------PTVVGVFTTQLNSIPGSAVCA 330

Query: 324 FPLDEVDRLAN----------------------RTRDACYTREGRAEDGTEVAYIEYDVN 361
           F +D+++++                        + R  C  + G AE         Y  +
Sbjct: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE--------AYKTS 382

Query: 362 SDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG----HT 417
            D     +  + ++P      P P+A       T +      +LTA++V    G    +T
Sbjct: 383 IDFPDETLSFIKSHPLMDSAVP-PIADEPWFTKTRVR----YRLTAISVDHSAGPYQNYT 437

Query: 418 IAFLGDSQGQLHRVYL--GPGSDGHPYSTQSIQ-----QGSAVSRD------LTFDGTFE 464
           + F+G   G + +V     P S       + I+     + SA + +      L  D    
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497

Query: 465 HLYVMTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQ 522
            LYV   S ++++P++ C ++  C  SC+A RDPYCGW +  G C R +     +G EQ
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW-LSQGSCGRVTPGMLAEGYEQ 555


>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
          Length = 998

 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 80/359 (22%), Positives = 138/359 (38%), Gaps = 78/359 (21%)

Query: 217 HFVSAFARGASAYFLFLRRDLQAQS--RAFRAYVSRVCLRD---------QHYYSYVELP 265
           HF+ A   G   YF F    ++  +  +A  + V+R+C  D         +H+ S+++  
Sbjct: 222 HFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKAR 281

Query: 266 LACE--GGRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCA 323
           L C   G  +         T     +G            PTV    +    +   SA+CA
Sbjct: 282 LNCSVPGDSFFYFDVLQSITDIIQINGI-----------PTVVGVFTTQLNSIPGSAVCA 330

Query: 324 FPLDEVDRLAN----------------------RTRDACYTREGRAEDGTEVAYIEYDVN 361
           F +D+++++                        + R  C  + G AE         Y  +
Sbjct: 331 FSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAE--------AYKTS 382

Query: 362 SDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG----HT 417
            D     +  + ++P      P P+A       T +      +LTA++V    G    +T
Sbjct: 383 IDFPDETLSFIKSHPLMDSAVP-PIADEPWFTKTRVR----YRLTAISVDHSAGPYQNYT 437

Query: 418 IAFLGDSQGQLHRVYL--GPGSDGHPYSTQSIQ-----QGSAVSRD------LTFDGTFE 464
           + F+G   G + +V     P S       + I+     + SA + +      L  D    
Sbjct: 438 VIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHH 497

Query: 465 HLYVMTQSTLLKVPVASCAQHLDCA-SCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQ 522
            LYV   S ++++P++ C ++  C  SC+A RDPYCGW +  G C R +     +G EQ
Sbjct: 498 ALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW-LSQGSCGRVTPGMLAEGYEQ 555


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 55/160 (34%), Positives = 66/160 (41%), Gaps = 26/160 (16%)

Query: 676 QSPLVSPDPPARGGPSP--SPPTAPKALATP-APDTLPVE------PGAPSTATASDISP 726
           Q+P     PP +  PSP  SPP +P A  +P AP+ L V          PS    +  SP
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454

Query: 727 GASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPED 786
            ASP    P  P A   S + P     PL   PSPP           A     PSATP  
Sbjct: 455 PASP----PVSPSATPPSQAPPSLAAPPLQVPPSPP-----------ASPPMSPSATPPP 499

Query: 787 LLASPLS--PSEVAAVPPADPGPEALHPTVPLDLPPATVP 824
               PL+  P ++A  PP  P   A  P   L  PPA+ P
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 62/190 (32%), Positives = 76/190 (40%), Gaps = 41/190 (21%)

Query: 667 DAGPMVAS-HQSPLVSPDPPARGGPSPSPPTAPKA---------LATPAP---------- 706
           DA P +     SPL +P P A    S +PPT P           LATP P          
Sbjct: 291 DAAPALGPLSSSPLATPSPSA-ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349

Query: 707 --DTLPVEPGA-PSTATASDISP--GASPSLL--SPWGPWAGSGSISSPGSTGSPLHEEP 759
              TLP  P   PS AT S  SP   A+ S L   P  P A     + P     PL   P
Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409

Query: 760 SPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADP-----GPEALHPTV 814
           SPP+  + P + +  P+   P+A    LL +P SP      PP+ P      P A  P  
Sbjct: 410 SPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSP------PPSPPVQAPFSPPASPPVS 461

Query: 815 PLDLPPATVP 824
           P   PP+  P
Sbjct: 462 PSATPPSQAP 471



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 58/191 (30%), Positives = 76/191 (39%), Gaps = 37/191 (19%)

Query: 665 SCDAGPMVASHQSPLVSPDPPAR---GGPS--------PSPPTAPKALATPAPDT----- 708
           S  A P + +  SP  +P   A    G P+        PSPP +P  LATP P       
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP--LATPPPQAPPALA 401

Query: 709 LPVEPGAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPP--SPQN 766
           LP     PS   +  +SP A+PS   P  P A +  +       +P    PSPP  +P +
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPS---PQAPNALAVHLLQ-----APFSPPPSPPVQAPFS 453

Query: 767 GPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLDLPPATVPAT 826
            P +   +P+   PS  P  L A PL       VPP+ P   A  P  P   PP   P  
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQ------VPPSPP---ASPPMSPSATPPPQAPPP 504

Query: 827 TFPGAMGSVKP 837
                +   KP
Sbjct: 505 LAAPPLQLAKP 515



 Score = 51.6 bits (122), Expect = 8e-06
 Identities = 63/201 (31%), Positives = 79/201 (39%), Gaps = 37/201 (18%)

Query: 658 HLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPT-APKALATP---APDTLPVEP 713
           HL     S    P V +  SP  SP       PS +PP+ AP +LA P    P + P  P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPV----SPSATPPSQAPPSLAAPPLQVPPSPPASP 489

Query: 714 GAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVP 773
               +AT     P A P L +P    A     + P     PL   PSPP+   G     P
Sbjct: 490 PMSPSATP---PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 546

Query: 774 -APTDFRPSATP----EDLLASPL---------SPSEVAAVPPADPGPE----------A 809
            A     P ATP      +LA+PL         SP+  A   P  PGP+          A
Sbjct: 547 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 606

Query: 810 LHPTVPLDLPPATVPATTFPG 830
           L P  P   PP+  P++T  G
Sbjct: 607 LAPGPP--PPPSRSPSSTLSG 625



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 58/191 (30%), Positives = 74/191 (38%), Gaps = 34/191 (17%)

Query: 668 AGPMVASHQSPLVSP---DPPARGGPS----PSPP-------------TAPKALATPAPD 707
           A   ++S  +PL SP    P ARG P     PS P             T P+  A PA  
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297

Query: 708 TL---PVEPGAPSTATASDISP--GASPSLLSPWGPWAGSGSISSPGSTGSP-LHEEPSP 761
            L   P+   +PS A  S   P   A+P   S     A    ++ P  +  P L   PSP
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357

Query: 762 P-SPQNGPGTAVPAPT-----DFRPSATPEDLLASPLSPSEVAAVPP--ADPGPEALHPT 813
           P +P +   T++ +PT      F PS     L   P       A+PP  A P P A  P 
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417

Query: 814 VPLDLPPATVP 824
            PL  P    P
Sbjct: 418 SPLATPSPQAP 428



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 74/284 (26%), Positives = 90/284 (31%), Gaps = 80/284 (28%)

Query: 668 AGPMVASHQSPLVSPDPPARGGPSP-----------------SPPTAPKALATPAPDTLP 710
           A P +    SP  SP  P     +P                  PP AP ALATP    LP
Sbjct: 475 AAPPLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532

Query: 711 VEPG-----APSTATAS------------------------DISPGASPSLLSPWGPWAG 741
             P      AP + +AS                          SP ASP+L +P  P   
Sbjct: 533 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 592

Query: 742 SGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPT----DFRPSATPEDL---------- 787
               S  G   +       PP P   P + +  P         ++TPE+L          
Sbjct: 593 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 652

Query: 788 -LASPLSPSEVAAVPPA----DPGPEALH---PTVPLDLPPATVPATTFPGAMGSVKPAL 839
             ASP   +E+AA  PA     P P       P  PL  PPAT P        GS     
Sbjct: 653 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP--------GSADGLC 704

Query: 840 DWLTREGGE--LPEADEWTGGDAPAFSTSTLLSGDGDSAELEGP 881
                EG E   P       G +P  S     +G G  A    P
Sbjct: 705 TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748



 Score = 39.7 bits (91), Expect = 0.032
 Identities = 57/188 (30%), Positives = 73/188 (38%), Gaps = 42/188 (22%)

Query: 677 SPLVSPDPPARGGPSPSPPTAPKALAT---PAPDTLPVEPGAPSTATASDISPGASPSLL 733
           +P   P PP  G P  S  +A +   T   PA    P   G      +  +S  A+P L 
Sbjct: 193 APSARPRPPTEG-PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LS 250

Query: 734 SPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQN--------------------GPGT--- 770
           SP    A SG  S+ G+  +P H  PS P P+                     GP +   
Sbjct: 251 SP----ARSGP-SARGTPRAPAH--PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303

Query: 771 -AVPAPTDFRPSATPEDLLASPLSPSEVAAV----PPADPGPEALHPTVPLDLPPATVP- 824
            A P+P+    S  P  L A+P S S    +    P A P P A      L  PPAT P 
Sbjct: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363

Query: 825 -ATTFPGA 831
            ATT  G+
Sbjct: 364 QATTSLGS 371



 Score = 35.8 bits (81), Expect = 0.46
 Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 18/128 (14%)

Query: 663 KASCDAGPMVASHQSP-LVSPDPPARGGPSPSPPTAPKAL----ATPAPDTLPV--EPGA 715
           KA   A     + ++P L++P PP  G P P PP  P AL    A  A    P+    G 
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64

Query: 716 PSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAP 775
              AT  + +P A P+        AG+ S +      +    E +PP+    PG   P  
Sbjct: 65  IGGATIPESAPRAGPTRS------AGTSSRNPASRPPASGRGERAPPAKNTSPG---PVS 115

Query: 776 TDFRPSAT 783
           +  R S T
Sbjct: 116 SPGRASGT 123


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 55/160 (34%), Positives = 66/160 (41%), Gaps = 26/160 (16%)

Query: 676 QSPLVSPDPPARGGPSP--SPPTAPKALATP-APDTLPVE------PGAPSTATASDISP 726
           Q+P     PP +  PSP  SPP +P A  +P AP+ L V          PS    +  SP
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415

Query: 727 GASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPED 786
            ASP    P  P A   S + P     PL   PSPP           A     PSATP  
Sbjct: 416 PASP----PVSPSATPPSQAPPSLAAPPLQVPPSPP-----------ASPPMSPSATPPP 460

Query: 787 LLASPLS--PSEVAAVPPADPGPEALHPTVPLDLPPATVP 824
               PL+  P ++A  PP  P   A  P   L  PPA+ P
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 58/200 (29%), Positives = 70/200 (35%), Gaps = 34/200 (17%)

Query: 667 DAGPMVAS-HQSPLVSPDPPARGGPS--------PSPPTAPKALAT-------------- 703
           DA P +     SPL +P P A   PS        PSPP  P + AT              
Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 341

Query: 704 -PAPDTLPVE---PGAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEP 759
            P+P   P+    P AP       +    SP    P  P A + S  +P +    L + P
Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA-TPSPQAPNALAVHLLQAP 400

Query: 760 --SPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEALHPTVPLD 817
              PPSP      + PA     PSATP     S   PS  A      P P A  P  P  
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPP----SQAPPSLAAPPLQVPPSPPASPPMSPSA 456

Query: 818 LPPATVPATTFPGAMGSVKP 837
            PP   P       +   KP
Sbjct: 457 TPPPQAPPPLAAPPLQLAKP 476



 Score = 51.6 bits (122), Expect = 8e-06
 Identities = 63/201 (31%), Positives = 79/201 (39%), Gaps = 37/201 (18%)

Query: 658 HLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPT-APKALATP---APDTLPVEP 713
           HL     S    P V +  SP  SP       PS +PP+ AP +LA P    P + P  P
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPV----SPSATPPSQAPPSLAAPPLQVPPSPPASP 450

Query: 714 GAPSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVP 773
               +AT     P A P L +P    A     + P     PL   PSPP+   G     P
Sbjct: 451 PMSPSATP---PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507

Query: 774 -APTDFRPSATP----EDLLASPL---------SPSEVAAVPPADPGPE----------A 809
            A     P ATP      +LA+PL         SP+  A   P  PGP+          A
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567

Query: 810 LHPTVPLDLPPATVPATTFPG 830
           L P  P   PP+  P++T  G
Sbjct: 568 LAPGPP--PPPSRSPSSTLSG 586



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 51/163 (31%), Positives = 65/163 (39%), Gaps = 30/163 (18%)

Query: 684 PPARGGPSPSPPTAPKALATPAP------------DTLPVEPGA-PSTATASDISP--GA 728
           PP +       P +   LATP+P             TLP  P   PS AT S  SP   A
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337

Query: 729 SPSLL--SPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPED 786
           + S L   P  P A     + P     PL   PSPP+  + P + +  P+   P+A    
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVH 395

Query: 787 LLASPLSPSEVAAVPPADP-----GPEALHPTVPLDLPPATVP 824
           LL +P SP      PP+ P      P A  P  P   PP+  P
Sbjct: 396 LLQAPFSP------PPSPPVQAPFSPPASPPVSPSATPPSQAP 432



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 74/284 (26%), Positives = 90/284 (31%), Gaps = 80/284 (28%)

Query: 668 AGPMVASHQSPLVSPDPPARGGPSP-----------------SPPTAPKALATPAPDTLP 710
           A P +    SP  SP  P     +P                  PP AP ALATP    LP
Sbjct: 436 AAPPLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493

Query: 711 VEPG-----APSTATAS------------------------DISPGASPSLLSPWGPWAG 741
             P      AP + +AS                          SP ASP+L +P  P   
Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553

Query: 742 SGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPT----DFRPSATPEDL---------- 787
               S  G   +       PP P   P + +  P         ++TPE+L          
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 613

Query: 788 -LASPLSPSEVAAVPPA----DPGPEALH---PTVPLDLPPATVPATTFPGAMGSVKPAL 839
             ASP   +E+AA  PA     P P       P  PL  PPAT P        GS     
Sbjct: 614 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP--------GSADGLC 665

Query: 840 DWLTREGGE--LPEADEWTGGDAPAFSTSTLLSGDGDSAELEGP 881
                EG E   P       G +P  S     +G G  A    P
Sbjct: 666 TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709



 Score = 39.7 bits (91), Expect = 0.032
 Identities = 38/120 (31%), Positives = 49/120 (40%), Gaps = 14/120 (11%)

Query: 663 KASCDAGPMVASHQSP-LVSPDPPARGGPSPSPPTAPKAL----ATPAPDTLPV--EPGA 715
           KA   A     + ++P L++P PP  G P P PP  P AL    A  A    P+    G 
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64

Query: 716 PSTATASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAP 775
              AT  + +P A P+  S   P +G G  + P    SP        SP    GT  P P
Sbjct: 65  IGGATIPESAPRAGPTRTSR-PPASGRGERAPPAKNTSP----GPVSSPGRASGTTRPGP 119


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,033,305
Number of Sequences: 37866
Number of extensions: 5325962
Number of successful extensions: 36765
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 189
Number of HSP's successfully gapped in prelim test: 1504
Number of HSP's that attempted gapping in prelim test: 21604
Number of HSP's gapped (non-prelim): 10004
length of query: 2135
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2017
effective length of database: 13,779,330
effective search space: 27792908610
effective search space used: 27792908610
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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