Guide to the Human Genome
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Search of human proteins with 40217849

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40217849 zinc finger protein 46 [Homo sapiens]
         (435 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40217849 zinc finger protein 46 [Homo sapiens]                     885   0.0  
gi|24308241 zinc finger and BTB domain containing 2 [Homo sapiens]    245   5e-65
gi|8923885 myoneurin [Homo sapiens]                                    90   5e-18
gi|182509180 zinc finger and BTB domain containing 1 isoform 1 [...    88   1e-17
gi|182509178 zinc finger and BTB domain containing 1 isoform 2 [...    88   1e-17
gi|167234429 zinc finger and BTB domain containing 17 [Homo sapi...    84   3e-16
gi|19923242 zinc finger protein 161 homolog [Homo sapiens]             72   1e-12
gi|219689126 zinc finger protein 161 homolog [Homo sapiens]            72   1e-12
gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]           72   1e-12
gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]           72   1e-12
gi|139394579 zinc finger and BTB domain containing 40 [Homo sapi...    69   8e-12
gi|139394556 zinc finger and BTB domain containing 40 [Homo sapi...    69   8e-12
gi|16418383 transcriptional repressor NAC1 [Homo sapiens]              68   1e-11
gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]      68   1e-11
gi|212286156 zinc finger and BTB domain containing 42 [Homo sapi...    68   2e-11
gi|94721342 zinc finger and BTB domain containing 8A [Homo sapiens]    67   2e-11
gi|84872173 zinc finger protein 131 [Homo sapiens]                     67   3e-11
gi|139394599 hypermethylated in cancer 2 [Homo sapiens]                67   3e-11
gi|7662128 zinc finger and BTB domain containing 24 [Homo sapiens]     65   9e-11
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]      64   2e-10
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]       64   2e-10
gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]     64   3e-10
gi|223972645 zinc finger protein 509 [Homo sapiens]                    64   4e-10
gi|189217876 sal-like 1 isoform b [Homo sapiens]                       60   3e-09
gi|118442837 sal-like 1 isoform a [Homo sapiens]                       60   3e-09
gi|224591419 zinc finger and BTB domain containing 8B [Homo sapi...    59   7e-09
gi|148491106 zinc finger protein 295 isoform S [Homo sapiens]          59   9e-09
gi|148491088 zinc finger protein 295 isoform L [Homo sapiens]          59   9e-09
gi|50345873 zinc finger protein 295 isoform L [Homo sapiens]           59   9e-09
gi|209413766 zinc finger and BTB domain containing 43 [Homo sapi...    59   9e-09

>gi|40217849 zinc finger protein 46 [Homo sapiens]
          Length = 435

 Score =  885 bits (2287), Expect = 0.0
 Identities = 435/435 (100%), Positives = 435/435 (100%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
           MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC
Sbjct: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60

Query: 61  IKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSP 120
           IKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSP
Sbjct: 61  IKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSP 120

Query: 121 ETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLDDGT 180
           ETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLDDGT
Sbjct: 121 ETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLDDGT 180

Query: 181 ADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTENSVKIHLC 240
           ADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTENSVKIHLC
Sbjct: 181 ADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTENSVKIHLC 240

Query: 241 HYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSF 300
           HYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSF
Sbjct: 241 HYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSF 300

Query: 301 IVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPR 360
           IVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPR
Sbjct: 301 IVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPR 360

Query: 361 KSQLLEHMYTHKGKSYRYNRCQRFGNALAQRFQPYCDSWSDVSLKSSRLSQEHLDLPCAL 420
           KSQLLEHMYTHKGKSYRYNRCQRFGNALAQRFQPYCDSWSDVSLKSSRLSQEHLDLPCAL
Sbjct: 361 KSQLLEHMYTHKGKSYRYNRCQRFGNALAQRFQPYCDSWSDVSLKSSRLSQEHLDLPCAL 420

Query: 421 ESELTQENVDTILVE 435
           ESELTQENVDTILVE
Sbjct: 421 ESELTQENVDTILVE 435


>gi|24308241 zinc finger and BTB domain containing 2 [Homo sapiens]
          Length = 514

 Score =  245 bits (626), Expect = 5e-65
 Identities = 164/422 (38%), Positives = 228/422 (54%), Gaps = 64/422 (15%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
           MD A+H L+LLQQLN QREFGFLCDCTVAIGDVYFKAH++VLA+FSNYFKM+F+HQTSEC
Sbjct: 1   MDLANHGLILLQQLNAQREFGFLCDCTVAIGDVYFKAHKSVLASFSNYFKMLFVHQTSEC 60

Query: 61  IKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQ-VFS 119
           ++++PTDIQPDIFSYLLH+MYTGK   Q++D  RLE+GI+FLHA  L   A+  +Q  FS
Sbjct: 61  VRLKPTDIQPDIFSYLLHLMYTGKMAPQLIDPVRLEQGIKFLHAYPLIQEASLASQGAFS 120

Query: 120 -PETV--QSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGL 176
            P+ V   +S+LYGIQI+  Q   ++Q  ++  AP     +         Q Q+  A  L
Sbjct: 121 HPDQVFPLASSLYGIQIADHQ---LRQATKIASAPEKLGRDPRPQTSRISQEQVPEASQL 177

Query: 177 DDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTG--------- 227
              T++  +       +      P    Q    PE V +   P P  E T          
Sbjct: 178 SQLTSNLAQ-------VNRTNMTPSDPLQTSLSPELVSTPVPPPPPGEETNLEASSSDEQ 230

Query: 228 ----------PTFTENS---VKIHLCHYCGERFDSRSNLRQHLHTHVSGSLPF------- 267
                     P+  + +    K + CH CG RF  RS+LR+HL  H    +PF       
Sbjct: 231 PASLTIAHVKPSIMKRNGSFPKYYACHLCGRRFTLRSSLREHLQIHT--GVPFTSSQQGE 288

Query: 268 -GVPASIL-ESNDLG----EVHPLNENSEALECRRLSSFIVKENEQQPDHTNRGTTEPLQ 321
             VP ++   + DLG    EV      S++ E + +S   + + +QQ +     T  P  
Sbjct: 289 SRVPLTLCSNAADLGKDAMEVPEAGMISDS-ELQHISDSPIIDGQQQSE-----TPPPSD 342

Query: 322 ISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKGKSYRYNRC 381
           I+ +  + +  +  E+       ++RK  CTICG KF +KS   EHMY H GK ++ + C
Sbjct: 343 IADIDNLEQADQEREV-------KRRKYECTICGRKFIQKSHWREHMYIHTGKPFKCSTC 395

Query: 382 QR 383
            +
Sbjct: 396 DK 397


>gi|8923885 myoneurin [Homo sapiens]
          Length = 610

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 110/450 (24%), Positives = 182/450 (40%), Gaps = 71/450 (15%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
           M  + H   LL++LN QRE GFLCDCT+ IG+  FKAHR VLA+FS YF  I+   +   
Sbjct: 1   MQYSHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLASFSEYFGAIYRSTSENN 60

Query: 61  IKIQPTDIQPDIFSYLLHIMYTG---------KGPKQIVDHSRLEEGI----------RF 101
           + +  + ++ D F  LL  +YTG         K   Q  D+ ++EE +           F
Sbjct: 61  VFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKCKIKMEDFAF 120

Query: 102 LHADYLSHIAT-----EMNQVFSPETVQSSNLYG--------IQISTTQKTVVKQGLEVK 148
           +     + I++     E+NQ     T++  N           IQ +  Q  + K+  + K
Sbjct: 121 IANPSSTEISSITGNIELNQQTCLLTLRDYNNREKSEVSTDLIQANPKQGALAKKSSQTK 180

Query: 149 EAP----SSNSGNRAAVQG-----DHPQLQLSL-AIGLDDGTADQQRACPATQALE---- 194
           +      S  +G    VQ      ++  ++L L A  L     +Q         LE    
Sbjct: 181 KKKKAFNSPKTGQNKTVQYPSDILENASVELFLDANKLPTPVVEQVAQINDNSELELTSV 240

Query: 195 -EHQKP------PVSIKQER--CDPESVISQSHPSPSSEVTGPTFTENSVK--------- 236
            E+  P       V++K++R    P   + +   S  + V  P   ENS +         
Sbjct: 241 VENTFPAQDIVHTVTVKRKRGKSQPNCALKEHSMSNIASVKSPYEAENSGEELDQRYSKA 300

Query: 237 IHLCHYCGERFDSRSNLRQHLHTHVSGSLPFG---VPASILESNDLGEVHPLNENSEALE 293
             +C+ CG+ F   S+LR+H+  H  G  P+       +  + N L      +   +  +
Sbjct: 301 KPMCNTCGKVFSEASSLRRHMRIH-KGVKPYVCHLCGKAFTQCNQLKTHVRTHTGEKPYK 359

Query: 294 CRRL-SSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCT 352
           C      F  K         + G  +P +    +L    +  ++++     S ++   C 
Sbjct: 360 CELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHAR-KHSGEKPYVCD 418

Query: 353 ICGHKFPRKSQLLEHMYTHKG-KSYRYNRC 381
            CG +F + S L  H+  H G K Y  + C
Sbjct: 419 RCGQRFAQASTLTYHVRRHTGEKPYVCDTC 448



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 44/148 (29%), Positives = 61/148 (41%), Gaps = 31/148 (20%)

Query: 262 SGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSFIVKENE---QQPDHT-----N 313
           + S+   + A+ L +  + +V  +N+NSE      L    V EN    Q   HT      
Sbjct: 206 NASVELFLDANKLPTPVVEQVAQINDNSE------LELTSVVENTFPAQDIVHTVTVKRK 259

Query: 314 RGTTEP---LQISQVSLISKDTEPVE-------LNCNFSFSRKRKMSCTICGHKFPRKSQ 363
           RG ++P   L+   +S I+    P E       L+  +S   K K  C  CG  F   S 
Sbjct: 260 RGKSQPNCALKEHSMSNIASVKSPYEAENSGEELDQRYS---KAKPMCNTCGKVFSEASS 316

Query: 364 LLEHMYTHKG-KSYRYNRCQRFGNALAQ 390
           L  HM  HKG K Y  + C   G A  Q
Sbjct: 317 LRRHMRIHKGVKPYVCHLC---GKAFTQ 341



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 351 CTICGHKFPRKSQLLEHMYTHKG-KSYRYNRCQR 383
           C +CG  F + +QL  H+ TH G K Y+   C +
Sbjct: 332 CHLCGKAFTQCNQLKTHVRTHTGEKPYKCELCDK 365



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 8/62 (12%)

Query: 206 ERCDPESVISQSHPSPSSEVTGPTFTENSVKIHLCHYCGERFDSRSNLRQHLHTHVSGSL 265
           + C     +S S  + S + TG        K ++C  CG+ F S   L +H  +H +G  
Sbjct: 446 DTCGKAFAVSSSLITHSRKHTGE-------KPYICGICGKSFISSGELNKHFRSH-TGER 497

Query: 266 PF 267
           PF
Sbjct: 498 PF 499


>gi|182509180 zinc finger and BTB domain containing 1 isoform 1
           [Homo sapiens]
          Length = 713

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 76/263 (28%), Positives = 117/263 (44%), Gaps = 30/263 (11%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFI---HQT 57
           M   SHS  +LQQLN QRE+GFLCDC +AI D+YF+AH+AVLAA S+YF+M F+   H T
Sbjct: 1   MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 60

Query: 58  SECIKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQV 117
           ++ + +    I  + F  +L  MY GK         + +  + +L    L ++   +  +
Sbjct: 61  AQ-LNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQ---LYNVPDCLEDI 116

Query: 118 FSPETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLD 177
              +   SS+      S+ Q + +  G+ + E   + +GN A      P   ++      
Sbjct: 117 QDADC--SSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVN------ 168

Query: 178 DGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPS-SEVTGPTFTENSVK 236
             T   + A   +  L    +P   +    C   SV   S P    S   G +FT     
Sbjct: 169 --TPHNREADEESLQLGNFPEPLFDV----CKKSSVSKLSTPKERVSRRFGRSFT----- 217

Query: 237 IHLCHYCGERFDSRSNLRQHLHT 259
              C  CG  F     L +H+ T
Sbjct: 218 ---CDSCGFGFSCEKLLDEHVLT 237



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 10/23 (43%), Positives = 14/23 (60%)

Query: 238 HLCHYCGERFDSRSNLRQHLHTH 260
           H C+ CG+ F  R +LR+H   H
Sbjct: 578 HFCNLCGKGFYQRCHLREHYTVH 600


>gi|182509178 zinc finger and BTB domain containing 1 isoform 2
           [Homo sapiens]
          Length = 644

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 76/263 (28%), Positives = 117/263 (44%), Gaps = 30/263 (11%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFI---HQT 57
           M   SHS  +LQQLN QRE+GFLCDC +AI D+YF+AH+AVLAA S+YF+M F+   H T
Sbjct: 1   MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 60

Query: 58  SECIKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQV 117
           ++ + +    I  + F  +L  MY GK         + +  + +L    L ++   +  +
Sbjct: 61  AQ-LNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQ---LYNVPDCLEDI 116

Query: 118 FSPETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLD 177
              +   SS+      S+ Q + +  G+ + E   + +GN A      P   ++      
Sbjct: 117 QDADC--SSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVN------ 168

Query: 178 DGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPS-SEVTGPTFTENSVK 236
             T   + A   +  L    +P   +    C   SV   S P    S   G +FT     
Sbjct: 169 --TPHNREADEESLQLGNFPEPLFDV----CKKSSVSKLSTPKERVSRRFGRSFT----- 217

Query: 237 IHLCHYCGERFDSRSNLRQHLHT 259
              C  CG  F     L +H+ T
Sbjct: 218 ---CDSCGFGFSCEKLLDEHVLT 237



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 10/23 (43%), Positives = 14/23 (60%)

Query: 238 HLCHYCGERFDSRSNLRQHLHTH 260
           H C+ CG+ F  R +LR+H   H
Sbjct: 578 HFCNLCGKGFYQRCHLREHYTVH 600


>gi|167234429 zinc finger and BTB domain containing 17 [Homo
           sapiens]
          Length = 803

 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 102/461 (22%), Positives = 170/461 (36%), Gaps = 86/461 (18%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
           MD   HS  +L+QLN QR+ G LCDCT  +  V+FKAH+AVLAA S YFKM+F+ Q  + 
Sbjct: 1   MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVDQ-KDV 59

Query: 61  IKIQPTDIQPDIFSYLLHIMYTGK---GPKQIVD------HSRLEEGIRFLHA------- 104
           + +  ++        +L  MYT K    P+ + D        ++++ I   HA       
Sbjct: 60  VHLDISNAAG--LGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSLAEP 117

Query: 105 -----DYLSHIATEMNQVFSPETVQSSNLYGIQISTTQKTVVKQGLEVKE-----APSSN 154
                     +ATE     + E   +++         + T +    ++KE     A S+ 
Sbjct: 118 ATSPGGNAEALATEGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEERGGQAQSAA 177

Query: 155 SGNRAAVQGDHPQ---------------LQLSLAIGLDDGTADQQRACPATQALEEHQKP 199
           SG     + D P+                       L + +  +    PA +  EE ++ 
Sbjct: 178 SGAEQTEKADAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEEQKEQ 237

Query: 200 ---------PVSIKQERC------------DPESVISQSHPSPSSEVTG---PTFTENSV 235
                    P  +K+E              + ES  + S     SE  G    T+ + + 
Sbjct: 238 EEQEEEGAGPAEVKEEGSQLENGEAPEENENEESAGTDSGQELGSEARGLRSGTYGDRTE 297

Query: 236 K------IHLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENS 289
                  IH C  CG+ F    N ++H+  H +G  PF         +D        +  
Sbjct: 298 SKAYGSVIHKCEDCGKEFTHTGNFKRHIRIH-TGEKPFSCRECSKAFSDPAACKAHEKTH 356

Query: 290 EAL------ECRRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSF 343
             L      EC +    I   N  +  H+           ++   S + +  +L      
Sbjct: 357 SPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQL----VH 412

Query: 344 SRKRKMSCTICGHKFPRKSQLLEHMYTH-KGKSYRYNRCQR 383
           S ++   C  CG  F   +  + H+ TH   K ++   C +
Sbjct: 413 SGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDK 453



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 43/190 (22%), Positives = 72/190 (37%), Gaps = 32/190 (16%)

Query: 193 LEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTENSVKIHLCHYCGERFDSRSN 252
           L+ HQ      K  +CD      +S   P+S++     T ++ K H C +C ++F+   N
Sbjct: 405 LKRHQLVHSGEKPYQCD---YCGRSFSDPTSKMRHLE-THDTDKEHKCPHCDKKFNQVGN 460

Query: 253 LRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSFIVKENEQQPDHT 312
           L+ HL  H++           L+  + G+    + N      +R       E      H 
Sbjct: 461 LKAHLKIHIAD--------GPLKCRECGKQFTTSGN-----LKRHLRIHSGEKPYVCIHC 507

Query: 313 NRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHK 372
            R   +P  + +   I    +P +              C +CG  F + S L+ H+  H 
Sbjct: 508 QRQFADPGALQRHVRIHTGEKPCQ--------------CVMCGKAFTQASSLIAHVRQHT 553

Query: 373 G-KSYRYNRC 381
           G K Y   RC
Sbjct: 554 GEKPYVCERC 563



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 35/143 (24%), Positives = 59/143 (41%), Gaps = 14/143 (9%)

Query: 236 KIHLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLN-ENSEALEC 294
           K +LC  CG  F+   NLR H+ T   G         ILE  +  EV  +  ++   L  
Sbjct: 612 KPYLCDKCGRGFNRVDNLRSHVKTVHQGK----AGIKILEPEEGSEVSVVTVDDMVTLAT 667

Query: 295 RRLSSFIVKENEQQP--DHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCT 352
             L++  V +    P         TE L+ +++S   K  +  + N +  +      +C 
Sbjct: 668 EALAATAVTQLTVVPVGAAVTADETEVLK-AEISKAVKQVQEEDPNTHILY------ACD 720

Query: 353 ICGHKFPRKSQLLEHMYTHKGKS 375
            CG KF   + L +H+  H  ++
Sbjct: 721 SCGDKFLDANSLAQHVRIHTAQA 743


>gi|19923242 zinc finger protein 161 homolog [Homo sapiens]
          Length = 449

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 104/458 (22%), Positives = 171/458 (37%), Gaps = 83/458 (18%)

Query: 6   HSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQP 65
           H  + L+ LN QR  G  CD  + + DV F+AHR VLAA S YFK +F     +   +  
Sbjct: 18  HKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTYFKKLFKKLEVDSSSVIE 77

Query: 66  TD-IQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSPE--T 122
            D ++ DIF  +L+ MYT K   +  D + +    + L   +L  + ++   V SP+   
Sbjct: 78  IDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFLDKLCSQKRDVSSPDENN 137

Query: 123 VQSSNLYGIQIST-------TQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQ-------- 167
            QS + Y ++I+        TQ   V++  +  ++PS ++     V+G  P         
Sbjct: 138 GQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDT-----VEGTPPSQEDGKSPT 192

Query: 168 --LQLSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEV 225
             L++  AI  + G+ + ++     Q +E  + P       +       +        E 
Sbjct: 193 TTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALTFNDGMSEVKDEQ 252

Query: 226 T-GPTFTENSVKIHL-----------CHYCGERFDSRSNLRQH--LHTHVSGSLPFGVPA 271
           T G T   + +K              C  CG+ F     LR+H  LHT     +      
Sbjct: 253 TPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADRPFVCEMCTK 312

Query: 272 SILESNDLGEVHPLNENSEALECRRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKD 331
                  L E   ++   +   C       ++     PD                   K 
Sbjct: 313 GFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIR----APD------------------LKK 350

Query: 332 TEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKG-KSYRYNRCQR-FGNALA 389
            E V        S +R  +C +C   F  KS L +H   H+G K +    C + F  A  
Sbjct: 351 HERVH-------SNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKA-- 401

Query: 390 QRFQPYCDSWSDVSLKSSRLSQEHLDL-PCALESELTQ 426
                     SD+    + +  E   + P A++SE  Q
Sbjct: 402 ----------SDLKRHENNMHSERKQVTPSAIQSETEQ 429


>gi|219689126 zinc finger protein 161 homolog [Homo sapiens]
          Length = 449

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 104/458 (22%), Positives = 171/458 (37%), Gaps = 83/458 (18%)

Query: 6   HSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQP 65
           H  + L+ LN QR  G  CD  + + DV F+AHR VLAA S YFK +F     +   +  
Sbjct: 18  HKTLFLKTLNEQRLEGEFCDIAIVVEDVKFRAHRCVLAACSTYFKKLFKKLEVDSSSVIE 77

Query: 66  TD-IQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSPE--T 122
            D ++ DIF  +L+ MYT K   +  D + +    + L   +L  + ++   V SP+   
Sbjct: 78  IDFLRSDIFEEVLNYMYTAKISVKKEDVNLMMSSGQILGIRFLDKLCSQKRDVSSPDENN 137

Query: 123 VQSSNLYGIQIST-------TQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQ-------- 167
            QS + Y ++I+        TQ   V++  +  ++PS ++     V+G  P         
Sbjct: 138 GQSKSKYCLKINRPIGDAADTQDDDVEEIGDQDDSPSDDT-----VEGTPPSQEDGKSPT 192

Query: 168 --LQLSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEV 225
             L++  AI  + G+ + ++     Q +E  + P       +       +        E 
Sbjct: 193 TTLRVQEAILKELGSEEVRKVNCYGQEVESMETPESKDLGSQTPQALTFNDGMSEVKDEQ 252

Query: 226 T-GPTFTENSVKIHL-----------CHYCGERFDSRSNLRQH--LHTHVSGSLPFGVPA 271
           T G T   + +K              C  CG+ F     LR+H  LHT     +      
Sbjct: 253 TPGWTTAASDMKFEYLLYGHHREQIACQACGKTFSDEGRLRKHEKLHTADRPFVCEMCTK 312

Query: 272 SILESNDLGEVHPLNENSEALECRRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKD 331
                  L E   ++   +   C       ++     PD                   K 
Sbjct: 313 GFTTQAHLKEHLKIHTGYKPYSCEVCGKSFIR----APD------------------LKK 350

Query: 332 TEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKG-KSYRYNRCQR-FGNALA 389
            E V        S +R  +C +C   F  KS L +H   H+G K +    C + F  A  
Sbjct: 351 HERVH-------SNERPFACHMCDKAFKHKSHLKDHERRHRGEKPFVCGSCTKAFAKA-- 401

Query: 390 QRFQPYCDSWSDVSLKSSRLSQEHLDL-PCALESELTQ 426
                     SD+    + +  E   + P A++SE  Q
Sbjct: 402 ----------SDLKRHENNMHSERKQVTPSAIQSETEQ 429


>gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]
          Length = 522

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 38/86 (44%), Positives = 50/86 (58%), Gaps = 2/86 (2%)

Query: 1  MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTS-- 58
          M+   HS  LLQ L+ QR  GFLCDCTV +GD  F+AHRAVLA+ S YF + +  Q    
Sbjct: 1  MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR 60

Query: 59 ECIKIQPTDIQPDIFSYLLHIMYTGK 84
          + + +    +    F+ LL  MY GK
Sbjct: 61 DIVHLNSDIVTAPAFALLLEFMYEGK 86


>gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]
          Length = 531

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 38/86 (44%), Positives = 50/86 (58%), Gaps = 2/86 (2%)

Query: 1  MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTS-- 58
          M+   HS  LLQ L+ QR  GFLCDCTV +GD  F+AHRAVLA+ S YF + +  Q    
Sbjct: 10 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR 69

Query: 59 ECIKIQPTDIQPDIFSYLLHIMYTGK 84
          + + +    +    F+ LL  MY GK
Sbjct: 70 DIVHLNSDIVTAPAFALLLEFMYEGK 95


>gi|139394579 zinc finger and BTB domain containing 40 [Homo
           sapiens]
          Length = 1239

 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 23/233 (9%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
           M+  ++S  LLQQL    +    CDCT++IG +YF+AH+ VLAA S  FK +     ++ 
Sbjct: 1   MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLL--DNTDT 58

Query: 61  IKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSP 120
           I I  + + P+ F+ LL +MYTGK P    + S++        AD L        Q+F  
Sbjct: 59  ISIDASVVSPEEFALLLEMMYTGKLPVGKHNFSKI-----ISLADSL--------QMFDV 105

Query: 121 ETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGL-DDG 179
                + L  +   + Q  VV+       APSS +  +   + + PQ+++  + G  +  
Sbjct: 106 AVSCKNLLTSLVNCSVQGQVVRD----VSAPSSETFRK---EPEKPQVEILSSEGAGEPH 158

Query: 180 TADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTE 232
           ++ +  A P      E ++   S+ QE         +S  +  +    PT  E
Sbjct: 159 SSPELAATPGGPVKAETEEAAHSVSQEMSVNSPTAQESQRNAETPAETPTTAE 211



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 1/35 (2%)

Query: 233  NSVKIHLCHYCGERFDSRSNLRQHLHTHVSGSLPF 267
            +S + H C  CG+ F + S L +H+ THV G  PF
Sbjct: 973  HSKEYHPCPTCGKIFSAPSMLERHVVTHVGGK-PF 1006



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 1/28 (3%)

Query: 240 CHYCGERFDSRSNLRQHLHTHVSGSLPF 267
           C  CG +F + S L+ HL  H +G  PF
Sbjct: 838 CEECGAKFAANSTLKNHLRLH-TGDRPF 864


>gi|139394556 zinc finger and BTB domain containing 40 [Homo
           sapiens]
          Length = 1239

 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 23/233 (9%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
           M+  ++S  LLQQL    +    CDCT++IG +YF+AH+ VLAA S  FK +     ++ 
Sbjct: 1   MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTLL--DNTDT 58

Query: 61  IKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSP 120
           I I  + + P+ F+ LL +MYTGK P    + S++        AD L        Q+F  
Sbjct: 59  ISIDASVVSPEEFALLLEMMYTGKLPVGKHNFSKI-----ISLADSL--------QMFDV 105

Query: 121 ETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGL-DDG 179
                + L  +   + Q  VV+       APSS +  +   + + PQ+++  + G  +  
Sbjct: 106 AVSCKNLLTSLVNCSVQGQVVRD----VSAPSSETFRK---EPEKPQVEILSSEGAGEPH 158

Query: 180 TADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTE 232
           ++ +  A P      E ++   S+ QE         +S  +  +    PT  E
Sbjct: 159 SSPELAATPGGPVKAETEEAAHSVSQEMSVNSPTAQESQRNAETPAETPTTAE 211



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 1/35 (2%)

Query: 233  NSVKIHLCHYCGERFDSRSNLRQHLHTHVSGSLPF 267
            +S + H C  CG+ F + S L +H+ THV G  PF
Sbjct: 973  HSKEYHPCPTCGKIFSAPSMLERHVVTHVGGK-PF 1006



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 1/28 (3%)

Query: 240 CHYCGERFDSRSNLRQHLHTHVSGSLPF 267
           C  CG +F + S L+ HL  H +G  PF
Sbjct: 838 CEECGAKFAANSTLKNHLRLH-TGDRPF 864


>gi|16418383 transcriptional repressor NAC1 [Homo sapiens]
          Length = 527

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 51/165 (30%), Positives = 71/165 (43%), Gaps = 18/165 (10%)

Query: 10  LLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQPTDIQ 69
           +L+ LN QR  G  CD +V +    FKAHRAVLAA S+YF+ +F +  S  +++ P  +Q
Sbjct: 16  ILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNNSRSAVVEL-PAAVQ 74

Query: 70  PDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSPETVQSSNLY 129
           P  F  +L   YTG+    + D   L     FL    +    TE     S  +  S    
Sbjct: 75  PQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEFFLKVSSPSCDS---- 130

Query: 130 GIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAI 174
                        QGL  +EAPSS   +  A     P     L +
Sbjct: 131 -------------QGLHAEEAPSSEPQSPVAQTSGWPACSTPLPL 162


>gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]
          Length = 677

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 35/86 (40%), Positives = 51/86 (59%), Gaps = 4/86 (4%)

Query: 1  MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFI----HQ 56
          MD   H   + QQLN QR  G LCDC + +G+ +FKAHR+VLAA S +F+ +F      Q
Sbjct: 1  MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQ 60

Query: 57 TSECIKIQPTDIQPDIFSYLLHIMYT 82
          T   I++    +  + F+ L+ +MYT
Sbjct: 61 TMNMIQLDSEVVTAEAFAALIDMMYT 86


>gi|212286156 zinc finger and BTB domain containing 42 [Homo
          sapiens]
          Length = 422

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 36/87 (41%), Positives = 49/87 (56%), Gaps = 3/87 (3%)

Query: 1  MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQ---T 57
          M+   H   LL +L  QRE GFLCDCTV +GD  F AHRAVLAA S YF + +  +   +
Sbjct: 1  MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGS 60

Query: 58 SECIKIQPTDIQPDIFSYLLHIMYTGK 84
           + +++    +    F  LL  MY G+
Sbjct: 61 RDTVRLNGDIVTAPAFGRLLDFMYEGR 87


>gi|94721342 zinc finger and BTB domain containing 8A [Homo
          sapiens]
          Length = 441

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 38/89 (42%), Positives = 49/89 (55%), Gaps = 7/89 (7%)

Query: 1  MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
          M+ +SH   LLQQLN QR     CDC++ +    FKAHR VL A S YFKM+    + E 
Sbjct: 1  MEISSHQSHLLQQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKE- 59

Query: 61 IKIQPTD-----IQPDIFSYLLHIMYTGK 84
             QPT        PD F+ +L  +Y+GK
Sbjct: 60 -TSQPTTATFQAFSPDTFTVILDFVYSGK 87


>gi|84872173 zinc finger protein 131 [Homo sapiens]
          Length = 589

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 79/313 (25%), Positives = 130/313 (41%), Gaps = 51/313 (16%)

Query: 6   HSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQP 65
           H  ++L +LN QRE     D T+ +   +FKAH+AVLAA S +F   F   T E + ++ 
Sbjct: 16  HHKMILDRLNEQREQDRFTDITLIVDGHHFKAHKAVLAACSKFFYKFFQEFTQEPL-VEI 74

Query: 66  TDIQPDIFSYLLHIMYTGK----GPKQIVDHSRLEEGIRFLHA------------DYLSH 109
             +    F +L+   YT K    G ++  D  +  E ++ L A              L  
Sbjct: 75  EGVSKMAFRHLIEFTYTAKLMIQGEEEANDVWKAAEFLQMLEAIKALEVRNKENSAPLEE 134

Query: 110 IATEMNQVFSPETVQSSNL--------------YGIQISTTQKTVVKQGLEVKEAPSSNS 155
             T  N+    +  ++SN+                ++I+     V  +G+E  E  +S  
Sbjct: 135 NTTGKNEAKKRKIAETSNVITESLPSAESEPVEIEVEIAEGTIEVEDEGIETLEEVASAK 194

Query: 156 GNRAAVQGDHPQLQLSLAIGLDDGTAD----------QQRACPA-TQALEEHQK--PPVS 202
            +   +Q        +LA+ L D T+           ++  CP+   + +EH K     S
Sbjct: 195 QSVKYIQSTGSSDDSALAL-LADITSKYRQGDRKGQIKEDGCPSDPTSKQEHMKSHSTES 253

Query: 203 IKQERCDP----ESVISQSHPSPSSEVTGPTFTENS-VKIHLCHYCGERFDSRSNLRQHL 257
            K E C+     ES   Q       E  G +  + +  KIH+C YC ++FD   + ++HL
Sbjct: 254 FKCEICNKRYLRESAWKQHLNCYHLEEGGVSKKQRTGKKIHVCQYCEKQFDHFGHFKEHL 313

Query: 258 HTHVSGSLPFGVP 270
             H +G  PF  P
Sbjct: 314 RKH-TGEKPFECP 325


>gi|139394599 hypermethylated in cancer 2 [Homo sapiens]
          Length = 615

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 35/84 (41%), Positives = 48/84 (57%), Gaps = 2/84 (2%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
           M+  SHS  LL QLN QR  GFLCD  + + +  F+AH+ VLAA S YFK + +H     
Sbjct: 23  MELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLH--DNL 80

Query: 61  IKIQPTDIQPDIFSYLLHIMYTGK 84
           I +    +   +F  +L  +YTGK
Sbjct: 81  INLDTDMVSSTVFQQILDFIYTGK 104



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 38/169 (22%), Positives = 63/169 (37%), Gaps = 22/169 (13%)

Query: 237 IHLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRR 296
           +++C  C + F S   L  H+ TH    L F       E+   G      E +E L    
Sbjct: 441 LYVCIPCAKGFPSSEQLNAHVETHTEEEL-FIKEEGAYETGSGGA----EEEAEDLSAPS 495

Query: 297 LSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELN-CNFSFSRKRKMS----- 350
            +++  +    +     +   +P  + Q       T P   N C   F+++  M+     
Sbjct: 496 -AAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRS 554

Query: 351 --------CTICGHKFPRKSQLLEHMYTHKGKSYRYNRCQRFGNALAQR 391
                   C  CG +F R+ +L EHM  H G+  +   CQ  G    Q+
Sbjct: 555 HLGLKPFACDECGMRFTRQYRLTEHMRVHSGE--KPYECQLCGGKFTQQ 601


>gi|7662128 zinc finger and BTB domain containing 24 [Homo sapiens]
          Length = 697

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 94/409 (22%), Positives = 164/409 (40%), Gaps = 69/409 (16%)

Query: 5   SHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQ 64
           +HS  +L     QR+ GFLCD T+ + +V+F+AH+A+LAA S YF M+F  +      I 
Sbjct: 18  AHSDTVLASFEDQRKKGFLCDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIY 77

Query: 65  PTD-IQPDIFSYLLHIMYTG------KGPKQIVDHSR------LEEGIRFLHADYLSHIA 111
             + +  D F  LL  +YTG      K  +QI+  ++      L +       ++ S   
Sbjct: 78  MLEGMVADTFGILLEFIYTGYLHASEKSTEQILATAQFLKVYDLVKAYTDFQNNHSSPKP 137

Query: 112 TEMNQVFSPETV---------QSSNLYGIQISTTQ----KTVVKQGLEVKEAPSSNSGNR 158
           T +N   +P  V         +       +++T Q    +   ++ ++++   S  +   
Sbjct: 138 TTLNTAGAPVVVIPNKKNDPPKRKRGRPKKVNTLQEEKSELAAEEEIQLRVNNSVQNRQN 197

Query: 159 AAVQGDHPQLQLSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSH 218
             V+GD   L   +A        +++ + P  +   E + P    K E  DP++   Q+ 
Sbjct: 198 FVVKGDSGVLNEQIA------AKEKEESEPTCEPSREEEMPVE--KDENYDPKTEDGQAS 249

Query: 219 PSPSSEVTGPTFTENSVKIHLCHYCGERFDSRSNLRQHLHTHVSG--SLPFGVPASILES 276
            S  S+         SVK+      G++ D  S  R      + G    P G  A     
Sbjct: 250 QSRYSK----RRIWRSVKLKDYKLVGDQEDHGSAKR------ICGRRKRPGGPEA---RC 296

Query: 277 NDLGEVHPLNENSEALECRRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVE 336
            D G+V   N             F+      Q  HT      P + ++          ++
Sbjct: 297 KDCGKVFKYNH------------FLA---IHQRSHTGE---RPFKCNECGKGFAQKHSLQ 338

Query: 337 LNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKG-KSYRYNRCQRF 384
           ++     + +R  +CT+C      K  LLEHM  H G KS+  ++C ++
Sbjct: 339 VHTRM-HTGERPYTCTVCSKALTTKHSLLEHMSLHSGQKSFTCDQCGKY 386



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 38/165 (23%), Positives = 67/165 (40%), Gaps = 23/165 (13%)

Query: 240 CHYCGERFDSRSNLRQHLHTHVSGSLPFGVPA---SILESNDLGEVHPLNENSEALECRR 296
           C+ CG+ F  + +L+ H   H +G  P+       ++   + L E   L+   ++  C +
Sbjct: 324 CNECGKGFAQKHSLQVHTRMH-TGERPYTCTVCSKALTTKHSLLEHMSLHSGQKSFTCDQ 382

Query: 297 LSSFIVKENEQQPDHTNRGTTEPL--------QISQVSLISKDTEPVELNCNFSFSRKRK 348
              +   +N Q   H    T   L        +   VS + K           + + ++ 
Sbjct: 383 CGKYF-SQNRQLKSHYRVHTGHSLPECKDCHRKFMDVSQLKKHLR--------THTGEKP 433

Query: 349 MSCTICGHKFPRKSQLLEHMYTHKG-KSYRYNRC-QRFGNALAQR 391
            +C ICG  F  KS L  H+  H+G K Y    C + F ++ A+R
Sbjct: 434 FTCEICGKSFTAKSSLQTHIRIHRGEKPYSCGICGKSFSDSSAKR 478



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 35/169 (20%), Positives = 59/169 (34%), Gaps = 11/169 (6%)

Query: 236 KIHLCHYCGERFDSRSNLRQHLHTHVSGSLP--FGVPASILESNDLGEVHPLNENSEALE 293
           K   C  CG+ F     L+ H   H   SLP         ++ + L +    +   +   
Sbjct: 376 KSFTCDQCGKYFSQNRQLKSHYRVHTGHSLPECKDCHRKFMDVSQLKKHLRTHTGEKPFT 435

Query: 294 CRRL-SSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCT 352
           C     SF  K + Q     +RG  +P           D+     +C    + K+  SC 
Sbjct: 436 CEICGKSFTAKSSLQTHIRIHRG-EKPYSCGICGKSFSDSSAKRRHC-ILHTGKKPFSCP 493

Query: 353 ICGHKFPRKSQLLEHMYTHKGKSYRYNRCQRFGNALAQ------RFQPY 395
            C  +F R   L  H+  H  + +  +     G++  +      + QPY
Sbjct: 494 ECNLQFARLDNLKAHLKIHSKEKHASDASSISGSSNTEEVRNILQLQPY 542


>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
          Length = 733

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 2/84 (2%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
           M+   HS  LL QLN QR  GFLCD  + + +  F+AH+ VLAA S Y K + +H     
Sbjct: 24  MEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVH--DNL 81

Query: 61  IKIQPTDIQPDIFSYLLHIMYTGK 84
           + +    + P +F  +L  +YTG+
Sbjct: 82  LNLDHDMVSPAVFRLVLDFIYTGR 105



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 44/195 (22%), Positives = 70/195 (35%), Gaps = 27/195 (13%)

Query: 216 QSHPSPSSEVTGP-TFTENSVKIHLCHYCGERFDSRSNLRQHLHTHV------------- 261
           + +P P      P +F +N   +++C  CG+ F S   L  H+  HV             
Sbjct: 417 EGYPCPHLAYGEPESFGDN---LYVCIPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAA 473

Query: 262 ---SGSLPFGVPASILESNDLGEVHPLNENSEALECRRLS-SFIVKENEQQPDHTNRGTT 317
              +G+   G P         G    L E      C     S+      +Q + T+  T 
Sbjct: 474 EVAAGAAGLGPPFGGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTR 533

Query: 318 E-PLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKGKSY 376
             P  I       + T    +  +      +  +C  CG +F R+ +L EHM  H G+  
Sbjct: 534 PYPCTICGKKFTQRGTMTRHMRSHLGL---KPFACDACGMRFTRQYRLTEHMRIHSGE-- 588

Query: 377 RYNRCQRFGNALAQR 391
           +   CQ  G   AQ+
Sbjct: 589 KPYECQVCGGKFAQQ 603


>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
          Length = 714

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 2/84 (2%)

Query: 1  MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
          M+   HS  LL QLN QR  GFLCD  + + +  F+AH+ VLAA S Y K + +H     
Sbjct: 5  MEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVH--DNL 62

Query: 61 IKIQPTDIQPDIFSYLLHIMYTGK 84
          + +    + P +F  +L  +YTG+
Sbjct: 63 LNLDHDMVSPAVFRLVLDFIYTGR 86



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 44/195 (22%), Positives = 70/195 (35%), Gaps = 27/195 (13%)

Query: 216 QSHPSPSSEVTGP-TFTENSVKIHLCHYCGERFDSRSNLRQHLHTHV------------- 261
           + +P P      P +F +N   +++C  CG+ F S   L  H+  HV             
Sbjct: 398 EGYPCPHLAYGEPESFGDN---LYVCIPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAA 454

Query: 262 ---SGSLPFGVPASILESNDLGEVHPLNENSEALECRRLS-SFIVKENEQQPDHTNRGTT 317
              +G+   G P         G    L E      C     S+      +Q + T+  T 
Sbjct: 455 EVAAGAAGLGPPFGGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTR 514

Query: 318 E-PLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKGKSY 376
             P  I       + T    +  +      +  +C  CG +F R+ +L EHM  H G+  
Sbjct: 515 PYPCTICGKKFTQRGTMTRHMRSHLGL---KPFACDACGMRFTRQYRLTEHMRIHSGE-- 569

Query: 377 RYNRCQRFGNALAQR 391
           +   CQ  G   AQ+
Sbjct: 570 KPYECQVCGGKFAQQ 584


>gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]
          Length = 574

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 35/87 (40%), Positives = 47/87 (54%), Gaps = 3/87 (3%)

Query: 1   MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQ---T 57
           M+   HS  LLQ L  QR  GFLCDCTV +G   F AHRAVLA+ S +F++ +  +    
Sbjct: 51  MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110

Query: 58  SECIKIQPTDIQPDIFSYLLHIMYTGK 84
            + + I    +    F  LL  MY G+
Sbjct: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQ 137


>gi|223972645 zinc finger protein 509 [Homo sapiens]
          Length = 765

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 35/80 (43%), Positives = 49/80 (61%), Gaps = 1/80 (1%)

Query: 4  ASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKI 63
          A+HS  LLQQL+ QR  G LCDC + +  V FKAH+ VLAAFS YF+ +F + +S+   +
Sbjct: 5  ATHSCHLLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRSLFQNSSSQKNDV 64

Query: 64 QPTDIQ-PDIFSYLLHIMYT 82
             D++       +L  MYT
Sbjct: 65 FHLDVKNVSGIGQILDFMYT 84



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 61/314 (19%), Positives = 114/314 (36%), Gaps = 27/314 (8%)

Query: 142 KQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLDDGTADQQRACPATQALEEHQKP-- 199
           K   +V E  S +   +         L+ + +   ++  +++  +C     + E ++P  
Sbjct: 319 KYAEQVSEPKSDDGLTKRLESASKNTLEKASSQSAEEKESEEVVSCENFNCISETERPED 378

Query: 200 PVSIKQERCDPESVISQSHPSPSSEVTGPTFTENS-VKIHL----------CHYCGERFD 248
           P +++ +     S   QS    + E+ G  F   S +++H           C+ CG+ F 
Sbjct: 379 PAALEDQ-----SQTLQSQRQYACELCGKPFKHPSNLELHKRSHTGEKPFECNICGKHFS 433

Query: 249 SRSNLRQHLHTHVSGSLPFGVPASILESNDLGEV--HPLNENSEALECRRLSSFIVKENE 306
              NL+ HL  H SG  P+            G+V  H +  + E      +         
Sbjct: 434 QAGNLQTHLRRH-SGEKPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDICGRGFSNFS 492

Query: 307 QQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLE 366
              +H    T + +        S + +   +      + +R  SC+ CG  F     L  
Sbjct: 493 NLKEHKKTHTADKVFTCDECGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFGGSGDLRR 552

Query: 367 HMYTHKG-KSYR---YNRCQRFGNALAQRFQPYCDSWSDVSLKSSRLSQ--EHLDLPCAL 420
           H+ TH G K Y     N+C      L +  + +C +  +       LSQ  E  DL  + 
Sbjct: 553 HVRTHTGEKPYTCEICNKCFTRSAVLRRHKKMHCKAGDESPDVLEELSQAIETSDLEKSQ 612

Query: 421 ESELTQENVDTILV 434
            S+   ++    L+
Sbjct: 613 SSDSFSQDTSVTLM 626


>gi|189217876 sal-like 1 isoform b [Homo sapiens]
          Length = 1227

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 71/346 (20%), Positives = 121/346 (34%), Gaps = 84/346 (24%)

Query: 119  SPETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGD-----------HPQ 167
            SP  ++ S++  ++    Q  ++  GL  +   S  S    +++GD             +
Sbjct: 757  SPLPLEMSSIAALE---NQMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDME 813

Query: 168  LQLSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSP------ 221
             Q + +  + + T+  Q   P+    E H+ P +  K +R  P    +   P+P      
Sbjct: 814  SQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAVPSEFANGLSPTPVNGGAL 873

Query: 222  -------------------------------SSEVTGPTFT-ENSVKIH----------L 239
                                           + ++ G TF  ++++ IH          +
Sbjct: 874  DLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFI 933

Query: 240  CHYCGERFDSRSNLRQHLHTHVSGSLPFGV--PASILESNDLGEVHPLNENSEALECRRL 297
            C  C   F ++ NL+QH+ TH    LP  +  P+S L  N    V P N  S  ++    
Sbjct: 934  CTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVN 993

Query: 298  SSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVEL-------NCNFSFSR----- 345
                V   + +   T+   + PL  S  S +     P           C  +FS      
Sbjct: 994  GFVHVSPQDSKDTPTSHVPSGPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQ 1053

Query: 346  --------KRKMSCTICGHKFPRKSQLLEHMYTHKGKSYRYNRCQR 383
                    ++  +CTICG  F  K  L  HM TH   S    R +R
Sbjct: 1054 IHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRR 1099



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 11/115 (9%)

Query: 238 HLCHYCGERFDSRSNLRQHLHTHVSGSLP-FGVPASILES--NDLGEVHPLNENSEALEC 294
           H C  C ++F +   L+QH+  H+ G +P   VP S  ES  +D G     N +      
Sbjct: 669 HSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGSFDEKNFDD----- 723

Query: 295 RRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKM 349
             L +F  +  E  P+ +   T +    SQ SL S    P+E++   +   + KM
Sbjct: 724 --LDNFSDENMEDCPEGSIPDTPKSADASQDSL-SSSPLPLEMSSIAALENQMKM 775



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 51/277 (18%), Positives = 101/277 (36%), Gaps = 20/277 (7%)

Query: 110 IATEMNQVFSPETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQ 169
           +A +  Q+   + ++    + I +  +Q   +       +     S N  +    H   Q
Sbjct: 137 LALQQQQIHQLQLIEQIR-HQILLLASQNADLPTSSSPSQGTLRTSANPLSTLSSHLSQQ 195

Query: 170 LSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPS-----SE 224
           L+ A GL    A Q  +    + L     PP+ + Q       + S S  SP+     + 
Sbjct: 196 LAAAAGLAQSLASQSASISGVKQL-----PPIQLPQSSSGNTIIPSNSGSSPNMNILAAA 250

Query: 225 VTGPTFTENSVKIHLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHP 284
           VT P+  + +      H       S S+    + + +S +    +P     ++      P
Sbjct: 251 VTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASNPLLPQQASANSVFPSPLP 310

Query: 285 LNENSEALECRRLSSFIVKENEQQPDHTN---RGTTEPLQISQ----VSLISKDTEPVEL 337
            N  + A +   LS+   +   + P+ T    + T++           + +      +++
Sbjct: 311 -NIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQI 369

Query: 338 NCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKGK 374
           +   S + +R   C ICG++F  K  L  H   HK K
Sbjct: 370 HLR-SHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 405


>gi|118442837 sal-like 1 isoform a [Homo sapiens]
          Length = 1324

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 71/346 (20%), Positives = 121/346 (34%), Gaps = 84/346 (24%)

Query: 119  SPETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGD-----------HPQ 167
            SP  ++ S++  ++    Q  ++  GL  +   S  S    +++GD             +
Sbjct: 854  SPLPLEMSSIAALE---NQMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDME 910

Query: 168  LQLSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSP------ 221
             Q + +  + + T+  Q   P+    E H+ P +  K +R  P    +   P+P      
Sbjct: 911  SQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAVPSEFANGLSPTPVNGGAL 970

Query: 222  -------------------------------SSEVTGPTFT-ENSVKIH----------L 239
                                           + ++ G TF  ++++ IH          +
Sbjct: 971  DLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFI 1030

Query: 240  CHYCGERFDSRSNLRQHLHTHVSGSLPFGV--PASILESNDLGEVHPLNENSEALECRRL 297
            C  C   F ++ NL+QH+ TH    LP  +  P+S L  N    V P N  S  ++    
Sbjct: 1031 CTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVN 1090

Query: 298  SSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVEL-------NCNFSFSR----- 345
                V   + +   T+   + PL  S  S +     P           C  +FS      
Sbjct: 1091 GFVHVSPQDSKDTPTSHVPSGPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQ 1150

Query: 346  --------KRKMSCTICGHKFPRKSQLLEHMYTHKGKSYRYNRCQR 383
                    ++  +CTICG  F  K  L  HM TH   S    R +R
Sbjct: 1151 IHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRR 1196



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 11/115 (9%)

Query: 238 HLCHYCGERFDSRSNLRQHLHTHVSGSLP-FGVPASILES--NDLGEVHPLNENSEALEC 294
           H C  C ++F +   L+QH+  H+ G +P   VP S  ES  +D G     N +      
Sbjct: 766 HSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGSFDEKNFDD----- 820

Query: 295 RRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKM 349
             L +F  +  E  P+ +   T +    SQ SL S    P+E++   +   + KM
Sbjct: 821 --LDNFSDENMEDCPEGSIPDTPKSADASQDSL-SSSPLPLEMSSIAALENQMKM 872



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 51/277 (18%), Positives = 101/277 (36%), Gaps = 20/277 (7%)

Query: 110 IATEMNQVFSPETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQ 169
           +A +  Q+   + ++    + I +  +Q   +       +     S N  +    H   Q
Sbjct: 234 LALQQQQIHQLQLIEQIR-HQILLLASQNADLPTSSSPSQGTLRTSANPLSTLSSHLSQQ 292

Query: 170 LSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPS-----SE 224
           L+ A GL    A Q  +    + L     PP+ + Q       + S S  SP+     + 
Sbjct: 293 LAAAAGLAQSLASQSASISGVKQL-----PPIQLPQSSSGNTIIPSNSGSSPNMNILAAA 347

Query: 225 VTGPTFTENSVKIHLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHP 284
           VT P+  + +      H       S S+    + + +S +    +P     ++      P
Sbjct: 348 VTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASNPLLPQQASANSVFPSPLP 407

Query: 285 LNENSEALECRRLSSFIVKENEQQPDHTN---RGTTEPLQISQ----VSLISKDTEPVEL 337
            N  + A +   LS+   +   + P+ T    + T++           + +      +++
Sbjct: 408 -NIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQI 466

Query: 338 NCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKGK 374
           +   S + +R   C ICG++F  K  L  H   HK K
Sbjct: 467 HLR-SHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 502


>gi|224591419 zinc finger and BTB domain containing 8B [Homo
          sapiens]
          Length = 495

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 31/87 (35%), Positives = 47/87 (54%), Gaps = 3/87 (3%)

Query: 1  MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSEC 60
          M+  S+   LL +LN QR+  F CDC++ +    FKAHR +L A S YF+ + IH   + 
Sbjct: 1  MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60

Query: 61 IKIQPTD---IQPDIFSYLLHIMYTGK 84
           +        +  D FS +L  +Y+GK
Sbjct: 61 GRHSTASLDIVTSDAFSIILDFLYSGK 87


>gi|148491106 zinc finger protein 295 isoform S [Homo sapiens]
          Length = 865

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 30/79 (37%), Positives = 49/79 (62%), Gaps = 1/79 (1%)

Query: 5  SHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQ 64
          +H++ LL  LN +R  G LCD  + +GD  F+AH+ VLAA S YF+ +F ++ +E   + 
Sbjct: 11 AHAISLLSALNEERLKGQLCDVLLIVGDQKFRAHKNVLAASSEYFQSLFTNKENESQTVF 70

Query: 65 PTDI-QPDIFSYLLHIMYT 82
            D  +PD F  +L+ +Y+
Sbjct: 71 QLDFCEPDAFDNVLNYIYS 89



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 42/195 (21%), Positives = 74/195 (37%), Gaps = 28/195 (14%)

Query: 197 QKPPVSIKQERCDPESVISQSHPSPSSEVT-------GPTFTEN-----------SVKIH 238
           ++ PV   +E   PE+  +     PS E +       G  FT +           SVK  
Sbjct: 678 KEEPVEEAEEEA-PEASTAPKEAGPSKEASLWPCEKCGKMFTVHKQLERHQELLCSVKPF 736

Query: 239 LCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLS 298
           +CH C + F +   L  H  +H+S        AS   ++   EV P+  NS +       
Sbjct: 737 ICHVCNKAFRTNFRLWSHFQSHMS-------QASEESAHKESEVCPVPTNSPSPPPLPPP 789

Query: 299 SFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCN--FSFSRKRKMSCTICGH 356
             + K    +PD     +  P   ++   + ++++ +  +     + + KR+  C +C  
Sbjct: 790 PPLPKIQPLEPDSPTGLSENPTPATEKLFVPQESDTLFYHAPPLSAITFKRQFMCKLCHR 849

Query: 357 KFPRKSQLLEHMYTH 371
            F     L  H  TH
Sbjct: 850 TFKTAFSLWSHEQTH 864


>gi|148491088 zinc finger protein 295 isoform L [Homo sapiens]
          Length = 1066

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 30/79 (37%), Positives = 49/79 (62%), Gaps = 1/79 (1%)

Query: 5  SHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQ 64
          +H++ LL  LN +R  G LCD  + +GD  F+AH+ VLAA S YF+ +F ++ +E   + 
Sbjct: 11 AHAISLLSALNEERLKGQLCDVLLIVGDQKFRAHKNVLAASSEYFQSLFTNKENESQTVF 70

Query: 65 PTDI-QPDIFSYLLHIMYT 82
            D  +PD F  +L+ +Y+
Sbjct: 71 QLDFCEPDAFDNVLNYIYS 89



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 42/195 (21%), Positives = 74/195 (37%), Gaps = 28/195 (14%)

Query: 197  QKPPVSIKQERCDPESVISQSHPSPSSEVT-------GPTFTEN-----------SVKIH 238
            ++ PV   +E   PE+  +     PS E +       G  FT +           SVK  
Sbjct: 879  KEEPVEEAEEEA-PEASTAPKEAGPSKEASLWPCEKCGKMFTVHKQLERHQELLCSVKPF 937

Query: 239  LCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLS 298
            +CH C + F +   L  H  +H+S        AS   ++   EV P+  NS +       
Sbjct: 938  ICHVCNKAFRTNFRLWSHFQSHMS-------QASEESAHKESEVCPVPTNSPSPPPLPPP 990

Query: 299  SFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCN--FSFSRKRKMSCTICGH 356
              + K    +PD     +  P   ++   + ++++ +  +     + + KR+  C +C  
Sbjct: 991  PPLPKIQPLEPDSPTGLSENPTPATEKLFVPQESDTLFYHAPPLSAITFKRQFMCKLCHR 1050

Query: 357  KFPRKSQLLEHMYTH 371
             F     L  H  TH
Sbjct: 1051 TFKTAFSLWSHEQTH 1065



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 6/75 (8%)

Query: 238 HLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECR-- 295
           ++C YCG+ +   S  +QH+  H  G  P GV              P+ EN E  +CR  
Sbjct: 670 YICTYCGKAYRFLSQFKQHIKMH-PGEKPLGVNKVAKPKEHAPLASPV-ENKEVYQCRLC 727

Query: 296 --RLSSFIVKENEQQ 308
             +LSS + + + ++
Sbjct: 728 NAKLSSLLEQGSHER 742



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 28/145 (19%), Positives = 54/145 (37%), Gaps = 22/145 (15%)

Query: 233 NSVKIHLCHYCGERFDSRSNLRQHLHTH---VSGSLPFGVPASILESNDLGEVHPLNENS 289
           N  K + C  C +RF +   +  H  T    V    P     ++L+     ++  +    
Sbjct: 570 NPEKPYACDICHKRFHTNFKVWTHCQTQHGIVKNPSPASSSHAVLDEKFQRKLIDIVRER 629

Query: 290 EALECRRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKM 349
           E  +     + I+K    +P    + +++  Q+ + +L S+               K   
Sbjct: 630 EIKK-----ALIIKLRRGKPGFQGQSSSQAQQVIKRNLRSR--------------AKGAY 670

Query: 350 SCTICGHKFPRKSQLLEHMYTHKGK 374
            CT CG  +   SQ  +H+  H G+
Sbjct: 671 ICTYCGKAYRFLSQFKQHIKMHPGE 695


>gi|50345873 zinc finger protein 295 isoform L [Homo sapiens]
          Length = 1066

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 30/79 (37%), Positives = 49/79 (62%), Gaps = 1/79 (1%)

Query: 5  SHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQ 64
          +H++ LL  LN +R  G LCD  + +GD  F+AH+ VLAA S YF+ +F ++ +E   + 
Sbjct: 11 AHAISLLSALNEERLKGQLCDVLLIVGDQKFRAHKNVLAASSEYFQSLFTNKENESQTVF 70

Query: 65 PTDI-QPDIFSYLLHIMYT 82
            D  +PD F  +L+ +Y+
Sbjct: 71 QLDFCEPDAFDNVLNYIYS 89



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 42/195 (21%), Positives = 74/195 (37%), Gaps = 28/195 (14%)

Query: 197  QKPPVSIKQERCDPESVISQSHPSPSSEVT-------GPTFTEN-----------SVKIH 238
            ++ PV   +E   PE+  +     PS E +       G  FT +           SVK  
Sbjct: 879  KEEPVEEAEEEA-PEASTAPKEAGPSKEASLWPCEKCGKMFTVHKQLERHQELLCSVKPF 937

Query: 239  LCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLS 298
            +CH C + F +   L  H  +H+S        AS   ++   EV P+  NS +       
Sbjct: 938  ICHVCNKAFRTNFRLWSHFQSHMS-------QASEESAHKESEVCPVPTNSPSPPPLPPP 990

Query: 299  SFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCN--FSFSRKRKMSCTICGH 356
              + K    +PD     +  P   ++   + ++++ +  +     + + KR+  C +C  
Sbjct: 991  PPLPKIQPLEPDSPTGLSENPTPATEKLFVPQESDTLFYHAPPLSAITFKRQFMCKLCHR 1050

Query: 357  KFPRKSQLLEHMYTH 371
             F     L  H  TH
Sbjct: 1051 TFKTAFSLWSHEQTH 1065



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 6/75 (8%)

Query: 238 HLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECR-- 295
           ++C YCG+ +   S  +QH+  H  G  P GV              P+ EN E  +CR  
Sbjct: 670 YICTYCGKAYRFLSQFKQHIKMH-PGEKPLGVNKVAKPKEHAPLASPV-ENKEVYQCRLC 727

Query: 296 --RLSSFIVKENEQQ 308
             +LSS + + + ++
Sbjct: 728 NAKLSSLLEQGSHER 742



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 28/145 (19%), Positives = 54/145 (37%), Gaps = 22/145 (15%)

Query: 233 NSVKIHLCHYCGERFDSRSNLRQHLHTH---VSGSLPFGVPASILESNDLGEVHPLNENS 289
           N  K + C  C +RF +   +  H  T    V    P     ++L+     ++  +    
Sbjct: 570 NPEKPYACDICHKRFHTNFKVWTHCQTQHGIVKNPSPASSSHAVLDEKFQRKLIDIVRER 629

Query: 290 EALECRRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKM 349
           E  +     + I+K    +P    + +++  Q+ + +L S+               K   
Sbjct: 630 EIKK-----ALIIKLRRGKPGFQGQSSSQAQQVIKRNLRSR--------------AKGAY 670

Query: 350 SCTICGHKFPRKSQLLEHMYTHKGK 374
            CT CG  +   SQ  +H+  H G+
Sbjct: 671 ICTYCGKAYRFLSQFKQHIKMHPGE 695


>gi|209413766 zinc finger and BTB domain containing 43 [Homo
           sapiens]
          Length = 467

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 94/432 (21%), Positives = 165/432 (38%), Gaps = 67/432 (15%)

Query: 7   SLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQPT 66
           S  +LQ+LN QR+ G LCD ++ +    F+AH+AVLAA S YF    + + S  I + P 
Sbjct: 16  SSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCDQVLLKNSRRI-VLPD 74

Query: 67  DIQPDIFSYLLHIMYTGK---GPKQIVDHSRLEEGIRFLH-ADYLSHI--------ATEM 114
            + P +F  +L   YTG+      +IV +      ++  H  D  + +          ++
Sbjct: 75  VMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKL 134

Query: 115 NQVFSPETVQSSNLYGI----QISTTQKTVVKQGLEVKEAPSSNSGNRAAVQG---DHPQ 167
           N     ++  SS+  G+    ++ +   T   +  E+++  +     +  +     +H  
Sbjct: 135 NHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQLTEHEY 194

Query: 168 L---------QLSLAIGLDDGTADQQRACPATQALEEHQKPP-------VSIKQER---- 207
           L         +LS  +   DG      +         + KP        + +K ER    
Sbjct: 195 LPSNSSTEHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVKPERLEQA 254

Query: 208 CDPESVISQSHPSPSSEVTGPTFTENSVK---IHLCHYCGER-----FDSR---SNLRQH 256
           C+   V +       +E      TE++V+   +    + GE+     FD +   SN  + 
Sbjct: 255 CEGMDVHATYDEHQVTESINTVQTEHTVQPSGVEEDFHIGEKKVEAEFDEQADESNYDEQ 314

Query: 257 LHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSFI--VKENEQQPDHTNR 314
           +  + S    F        S +  + + +    EA      S  I  V   +++  H   
Sbjct: 315 VDFYGSSMEEF--------SGERSDGNLIGHRQEAALAAGYSENIEMVTGIKEEASHLGF 366

Query: 315 GTTEPLQISQV--SLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHK 372
             T+ L   Q   S   K      ++ +      R   C +CG KF  K  L+ HM  H 
Sbjct: 367 SATDKLYPCQCGKSFTHKSQRDRHMSMHLGL---RPYGCGVCGKKFKMKHHLVGHMKIHT 423

Query: 373 G-KSYRYNRCQR 383
           G K Y  N C +
Sbjct: 424 GIKPYECNICAK 435


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,932,828
Number of Sequences: 37866
Number of extensions: 780722
Number of successful extensions: 14803
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 688
Number of HSP's successfully gapped in prelim test: 358
Number of HSP's that attempted gapping in prelim test: 2968
Number of HSP's gapped (non-prelim): 7495
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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