Guide to the Human Genome
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Search of human proteins with 40217812

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40217812 cell cycle progression 2 protein isoform 1 [Homo
sapiens]
         (631 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40217812 cell cycle progression 2 protein isoform 1 [Homo sap...  1249   0.0  
gi|40217810 cell cycle progression 2 protein isoform 2 [Homo sap...   561   e-160
gi|13569848 cell cycle progression 2 protein isoform 2 [Homo sap...   561   e-160
gi|40068497 FAST kinase domains 3 [Homo sapiens]                      117   4e-26
gi|209969832 FAST kinase domains 2 [Homo sapiens]                      76   1e-13
gi|209969830 FAST kinase domains 2 [Homo sapiens]                      76   1e-13
gi|45267832 FAST kinase domains 2 [Homo sapiens]                       76   1e-13
gi|188497683 FAST kinase domains 1 [Homo sapiens]                      69   1e-11
gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo...    69   1e-11
gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Hom...    69   1e-11
gi|11141903 FAST kinase domains 5 [Homo sapiens]                       51   4e-06
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    32   1.8  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    32   1.8  
gi|239743173 PREDICTED: similar to solute carrier family 29 (nuc...    31   3.0  
gi|239508837 PREDICTED: similar to solute carrier family 29 (nuc...    31   3.0  
gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [H...    31   4.0  
gi|47578107 delangin isoform B [Homo sapiens]                          31   4.0  
gi|47578105 delangin isoform A [Homo sapiens]                          31   4.0  
gi|148727311 hypothetical protein LOC389690 [Homo sapiens]             31   4.0  
gi|239747159 PREDICTED: hypothetical protein XP_002343930 [Homo ...    30   5.2  
gi|27881506 ATP-binding cassette, sub-family F, member 2 isoform...    30   5.2  
gi|10947137 ATP-binding cassette, sub-family F, member 2 isoform...    30   5.2  
gi|9945318 MAX binding protein [Homo sapiens]                          30   5.2  
gi|52353320 FSHD region gene 2 [Homo sapiens]                          30   5.2  
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...    30   5.2  
gi|50233787 nuclear protein in testis [Homo sapiens]                   30   5.2  
gi|124487405 FSHD region gene 2 family, member B [Homo sapiens]        30   5.2  
gi|118572603 ubinuclein 1 [Homo sapiens]                               30   6.7  
gi|118572601 ubinuclein 1 [Homo sapiens]                               30   6.7  
gi|13129124 caspase recruitment domain protein 14 isoform 1 [Hom...    30   6.7  

>gi|40217812 cell cycle progression 2 protein isoform 1 [Homo
           sapiens]
          Length = 631

 Score = 1249 bits (3231), Expect = 0.0
 Identities = 631/631 (100%), Positives = 631/631 (100%)

Query: 1   MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60
           MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK
Sbjct: 1   MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60

Query: 61  ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120
           ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL
Sbjct: 61  ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120

Query: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180
           LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK
Sbjct: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180

Query: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240
           YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN
Sbjct: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240

Query: 241 RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY 300
           RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY
Sbjct: 241 RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY 300

Query: 301 AYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNR 360
           AYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNR
Sbjct: 301 AYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNR 360

Query: 361 AQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQ 420
           AQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQ
Sbjct: 361 AQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQ 420

Query: 421 QAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSGPLLPASAVAP 480
           QAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSGPLLPASAVAP
Sbjct: 421 QAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSGPLLPASAVAP 480

Query: 481 GPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDF 540
           GPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDF
Sbjct: 481 GPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDF 540

Query: 541 VAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVP 600
           VAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVP
Sbjct: 541 VAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVP 600

Query: 601 FYEWLELKSEWQKGAYLKDKMRKAVAEELAK 631
           FYEWLELKSEWQKGAYLKDKMRKAVAEELAK
Sbjct: 601 FYEWLELKSEWQKGAYLKDKMRKAVAEELAK 631


>gi|40217810 cell cycle progression 2 protein isoform 2 [Homo
           sapiens]
          Length = 521

 Score =  561 bits (1446), Expect = e-160
 Identities = 317/467 (67%), Positives = 350/467 (74%), Gaps = 32/467 (6%)

Query: 194 LSQEQHSQELLAELLTHLERRWTEIE------------DSHTLVTVMMKVGHLSEPLMNR 241
           + +E+ S   + + + HL ++ T  E            DS+    V++++ HL   L  +
Sbjct: 58  VEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHL---LSEK 114

Query: 242 LEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHL-VQKPFSLTKDVLLDVAY 300
            EDK L + +      L  +   +A+    ++  L    Y L + K     + V  +V +
Sbjct: 115 PEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRW 174

Query: 301 AYGKLSFH-------------QTQVSQRLATDLLS-LMPSLTSGEVAHCAKSFAL-LKWL 345
              KL +              Q Q SQ L  +LL+ L    T  E +H   +  + +  L
Sbjct: 175 RMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHL 234

Query: 346 SLPLFEAFA-QHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL 404
           S PL      +HVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL
Sbjct: 235 SEPLMNRLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL 294

Query: 405 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE 464
           EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE
Sbjct: 295 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE 354

Query: 465 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA 524
           YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA
Sbjct: 355 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA 414

Query: 525 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL 584
           EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL
Sbjct: 415 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL 474

Query: 585 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 631
           ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK
Sbjct: 475 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 521



 Score =  488 bits (1257), Expect = e-138
 Identities = 260/334 (77%), Positives = 272/334 (81%), Gaps = 43/334 (12%)

Query: 1   MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60
           MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK
Sbjct: 1   MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60

Query: 61  ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120
           ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL
Sbjct: 61  ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120

Query: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180
           LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK
Sbjct: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180

Query: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240
           YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN
Sbjct: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240

Query: 241 RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY 300
           RLEDK                                    H++ +   +T   L  V  
Sbjct: 241 RLEDK------------------------------------HVLNRAQDITLPHLCSVLL 264

Query: 301 AYGKLSFHQTQ-------VSQRLATDLLSLMPSL 327
           A+ +L+FH  Q       V ++L ++L  L P+L
Sbjct: 265 AFARLNFHPDQEDQFFSLVHEKLGSELPGLEPAL 298


>gi|13569848 cell cycle progression 2 protein isoform 2 [Homo
           sapiens]
          Length = 521

 Score =  561 bits (1446), Expect = e-160
 Identities = 317/467 (67%), Positives = 350/467 (74%), Gaps = 32/467 (6%)

Query: 194 LSQEQHSQELLAELLTHLERRWTEIE------------DSHTLVTVMMKVGHLSEPLMNR 241
           + +E+ S   + + + HL ++ T  E            DS+    V++++ HL   L  +
Sbjct: 58  VEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHL---LSEK 114

Query: 242 LEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHL-VQKPFSLTKDVLLDVAY 300
            EDK L + +      L  +   +A+    ++  L    Y L + K     + V  +V +
Sbjct: 115 PEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRW 174

Query: 301 AYGKLSFH-------------QTQVSQRLATDLLS-LMPSLTSGEVAHCAKSFAL-LKWL 345
              KL +              Q Q SQ L  +LL+ L    T  E +H   +  + +  L
Sbjct: 175 RMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHL 234

Query: 346 SLPLFEAFA-QHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL 404
           S PL      +HVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL
Sbjct: 235 SEPLMNRLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL 294

Query: 405 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE 464
           EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE
Sbjct: 295 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE 354

Query: 465 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA 524
           YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA
Sbjct: 355 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA 414

Query: 525 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL 584
           EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL
Sbjct: 415 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL 474

Query: 585 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 631
           ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK
Sbjct: 475 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 521



 Score =  488 bits (1257), Expect = e-138
 Identities = 260/334 (77%), Positives = 272/334 (81%), Gaps = 43/334 (12%)

Query: 1   MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60
           MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK
Sbjct: 1   MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60

Query: 61  ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120
           ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL
Sbjct: 61  ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120

Query: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180
           LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK
Sbjct: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180

Query: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240
           YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN
Sbjct: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240

Query: 241 RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY 300
           RLEDK                                    H++ +   +T   L  V  
Sbjct: 241 RLEDK------------------------------------HVLNRAQDITLPHLCSVLL 264

Query: 301 AYGKLSFHQTQ-------VSQRLATDLLSLMPSL 327
           A+ +L+FH  Q       V ++L ++L  L P+L
Sbjct: 265 AFARLNFHPDQEDQFFSLVHEKLGSELPGLEPAL 298


>gi|40068497 FAST kinase domains 3 [Homo sapiens]
          Length = 662

 Score =  117 bits (292), Expect = 4e-26
 Identities = 134/567 (23%), Positives = 244/567 (43%), Gaps = 42/567 (7%)

Query: 76  IKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL---LIQDAHFHQLLC 132
           +   T  EE+L  +     L    AA  L R+  +  +K  D+GL   +++++ F  L  
Sbjct: 106 LSNLTSSEEVLSFISTMETLPDTMAAGALQRICEV-EKKDGDQGLPKEILENSIFQALCF 164

Query: 133 LLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRK--LKYKHLAFLAES 190
               + + + + +L   L +L  L +   S  L ++  E + R+RK  ++ ++L  L ES
Sbjct: 165 QFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLVAECQNRLRKGGMEVRNLCILGES 224

Query: 191 CATL-SQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMM----KVGHLSEPLMNRLEDK 245
             TL S    + EL+   L   +      ED   L  ++     KV    +  +N++ + 
Sbjct: 225 LITLHSSGCVTLELIINQLQGEKLETFTPEDIVALYRILQACTEKVDE-HQTFLNKINNF 283

Query: 246 CLELVEHFGPNELRKVLVMLAAQSR-RSVPLLRAISYHLVQKPFSLTKDVLLDVAYAYGK 304
            L +V +  P  + ++L  L    + ++ PL+  +  ++V+     T + L  V  A+  
Sbjct: 284 SLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIY 343

Query: 305 LSFHQT----QVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNR 360
              H T     +  R+A   L+L P +    + +C++   L K    P+  A A+  + +
Sbjct: 344 FGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSRELILSK----PILNAVAETFVCQ 399

Query: 361 AQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQ 420
            +  +   + +++  F +LN+ P      F  +   L +      P   + L+ + C L 
Sbjct: 400 TEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHS-CSLN 458

Query: 421 QAREAELQAVLHPEFHIQFLGGK-SQKDQNTFQKLLHINATALLEYPEYSGP-LLPASAV 478
           +       A +     +Q L GK S  D  +  +L  +   ++LE P Y GP LLP   V
Sbjct: 459 ECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASVLECPFYKGPKLLPKYQV 518

Query: 479 APGPSALDRKVTPLQKELQETLK----GLLGSADKGSLEVATQYGWVLDAEVLLDSDGEF 534
               +      TP+  +L   +K     LLG+    + +V T Y + +D E+ LD +G  
Sbjct: 519 KSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFV 578

Query: 535 LPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGF 594
           LP              S +     KR+A        F S SK LLG+  + +RH+   G+
Sbjct: 579 LP--------------STANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGY 624

Query: 595 LIVDVPFYEWLELKSEWQKGAYLKDKM 621
            +V +P++E   LKS  +   YL+ K+
Sbjct: 625 QVVQIPYHEIGMLKSRRELVEYLQRKL 651


>gi|209969832 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 104/525 (19%), Positives = 217/525 (41%), Gaps = 28/525 (5%)

Query: 113 EKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEV 172
           +K  +K L+     F+QL   +  +   + +  L   L ++  LGIP+ +  +Q++ +  
Sbjct: 199 QKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVT 258

Query: 173 RWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVG 232
           + R+ +     L+ L+     +   ++   L       ++++  +IED  TL  VM  +G
Sbjct: 259 QERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVVMKCIG 318

Query: 233 HLSE-PLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLT 291
             +   L  +LE K L  ++ F     + +  +LAA + RS+ LL   S  ++       
Sbjct: 319 KDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNIHGCP 378

Query: 292 KDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFE 351
             +++++  +   L +H   + + LA  + +        +V      F  L +  + L +
Sbjct: 379 LRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGLMD 438

Query: 352 AFAQHVLNRAQDITLPHLCSVLLAFARLN--FHPDQEDQFFSLVHEKLGSELPGLEPALQ 409
            F + ++   + + + ++ S+L  ++ LN  +    ++QF  ++   L   L  +     
Sbjct: 439 LFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENL 498

Query: 410 VDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQ---NTFQKLLHINATALLEYP 466
           +D V++ C++     A    +L  +   + L     K+    +T    L ++ T  L   
Sbjct: 499 LDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDI 558

Query: 467 EYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEV 526
             S P LP    +   +A          ++ E L  LLG     S +V   + + +D E+
Sbjct: 559 ALSLPQLPRELPSSHTNA----------KVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEI 608

Query: 527 LLDSD-GEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLA 585
            +D++  + LP+ D             +     +R+A L      +   S    G   + 
Sbjct: 609 RMDTNRNQVLPLSDV----------DTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMK 658

Query: 586 RRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELA 630
            RH+ A GF ++ V  +E  +L+ E     +LK K+    A  +A
Sbjct: 659 MRHLNAMGFHVILVNNWEMDKLEME-DAVTFLKTKIYSVEALPVA 702


>gi|209969830 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 104/525 (19%), Positives = 217/525 (41%), Gaps = 28/525 (5%)

Query: 113 EKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEV 172
           +K  +K L+     F+QL   +  +   + +  L   L ++  LGIP+ +  +Q++ +  
Sbjct: 199 QKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVT 258

Query: 173 RWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVG 232
           + R+ +     L+ L+     +   ++   L       ++++  +IED  TL  VM  +G
Sbjct: 259 QERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVVMKCIG 318

Query: 233 HLSE-PLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLT 291
             +   L  +LE K L  ++ F     + +  +LAA + RS+ LL   S  ++       
Sbjct: 319 KDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNIHGCP 378

Query: 292 KDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFE 351
             +++++  +   L +H   + + LA  + +        +V      F  L +  + L +
Sbjct: 379 LRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGLMD 438

Query: 352 AFAQHVLNRAQDITLPHLCSVLLAFARLN--FHPDQEDQFFSLVHEKLGSELPGLEPALQ 409
            F + ++   + + + ++ S+L  ++ LN  +    ++QF  ++   L   L  +     
Sbjct: 439 LFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENL 498

Query: 410 VDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQ---NTFQKLLHINATALLEYP 466
           +D V++ C++     A    +L  +   + L     K+    +T    L ++ T  L   
Sbjct: 499 LDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDI 558

Query: 467 EYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEV 526
             S P LP    +   +A          ++ E L  LLG     S +V   + + +D E+
Sbjct: 559 ALSLPQLPRELPSSHTNA----------KVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEI 608

Query: 527 LLDSD-GEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLA 585
            +D++  + LP+ D             +     +R+A L      +   S    G   + 
Sbjct: 609 RMDTNRNQVLPLSDV----------DTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMK 658

Query: 586 RRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELA 630
            RH+ A GF ++ V  +E  +L+ E     +LK K+    A  +A
Sbjct: 659 MRHLNAMGFHVILVNNWEMDKLEME-DAVTFLKTKIYSVEALPVA 702


>gi|45267832 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 104/525 (19%), Positives = 217/525 (41%), Gaps = 28/525 (5%)

Query: 113 EKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEV 172
           +K  +K L+     F+QL   +  +   + +  L   L ++  LGIP+ +  +Q++ +  
Sbjct: 199 QKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVT 258

Query: 173 RWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVG 232
           + R+ +     L+ L+     +   ++   L       ++++  +IED  TL  VM  +G
Sbjct: 259 QERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVVMKCIG 318

Query: 233 HLSE-PLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLT 291
             +   L  +LE K L  ++ F     + +  +LAA + RS+ LL   S  ++       
Sbjct: 319 KDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNIHGCP 378

Query: 292 KDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFE 351
             +++++  +   L +H   + + LA  + +        +V      F  L +  + L +
Sbjct: 379 LRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGLMD 438

Query: 352 AFAQHVLNRAQDITLPHLCSVLLAFARLN--FHPDQEDQFFSLVHEKLGSELPGLEPALQ 409
            F + ++   + + + ++ S+L  ++ LN  +    ++QF  ++   L   L  +     
Sbjct: 439 LFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENL 498

Query: 410 VDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQ---NTFQKLLHINATALLEYP 466
           +D V++ C++     A    +L  +   + L     K+    +T    L ++ T  L   
Sbjct: 499 LDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDI 558

Query: 467 EYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEV 526
             S P LP    +   +A          ++ E L  LLG     S +V   + + +D E+
Sbjct: 559 ALSLPQLPRELPSSHTNA----------KVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEI 608

Query: 527 LLDSD-GEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLA 585
            +D++  + LP+ D             +     +R+A L      +   S    G   + 
Sbjct: 609 RMDTNRNQVLPLSDV----------DTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMK 658

Query: 586 RRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELA 630
            RH+ A GF ++ V  +E  +L+ E     +LK K+    A  +A
Sbjct: 659 MRHLNAMGFHVILVNNWEMDKLEME-DAVTFLKTKIYSVEALPVA 702


>gi|188497683 FAST kinase domains 1 [Homo sapiens]
          Length = 847

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 112/521 (21%), Positives = 225/521 (43%), Gaps = 62/521 (11%)

Query: 146 LSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLKYKHL-AFLAESCATLSQEQ-----H 199
           +S+ L    AL +  A  +++S    +  R+  + +KHL  +       ++QE       
Sbjct: 332 MSEDLTGEQALAVLGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQELTFLHFQ 391

Query: 200 SQELLAEL----LTHLERRWTEIEDSHTLVTV-MMKVGHLSEPLMNRLE---DKC-LELV 250
            +E  A+L    L++L+  +   E S  +  + ++   HL E  ++R+E    +C L  +
Sbjct: 392 RKEFFAKLRELLLSYLKNSFIPTEVSVLVRAISLLPSPHLDEVGISRIEAVLPQCDLNNL 451

Query: 251 EHFGPNELRKVL---VMLAAQSRRSVPLLRAISYHLVQK-PFSLTKDVLLDVAYAYGKLS 306
             F  + LR +    + L   + + + LL+ + ++  Q+   S + D+L     +    +
Sbjct: 452 SSFATSVLRWIQHDHMYLDNMTAKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNT 511

Query: 307 FHQTQVSQRLAT--DLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDI 364
           F ++ + + +AT    +  +  +  GE+A    S   L  L L    + A   + +    
Sbjct: 512 FPESLLEEMIATLQHFMDDINYINVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPF 571

Query: 365 TLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQARE 424
           T+P   +++  F+ LN+ P Q D+F     + L S L  L+P + V L ++L  L+   E
Sbjct: 572 TIP---AIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPE 628

Query: 425 AELQAVLHPEFHIQFLG---------GKSQKDQNTFQKLLHINATALLEYPEYSGPLLP- 474
             L+A+    F+I+FL            S+  +  F  L+ +N +  LE PE+  P    
Sbjct: 629 DLLKAI----FNIKFLARLDSQLEILSPSRSARVQFH-LMELNRSVCLECPEFQIPWFHD 683

Query: 475 --ASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDG 532
                   G   +D      Q+++ + L  +LG  +     V T Y   +D E +LD   
Sbjct: 684 RFCQQYNKGIGGMD----GTQQQIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKRK 739

Query: 533 EFLPVRDFVAPHLAQPTGSQSP------------PPGSKRLAFLRWEFPNFNSRSKDLLG 580
           + LP   + + ++A     + P            PPG++R+A    +          + G
Sbjct: 740 KPLP---YGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALEFLDSKALCRNIPHMKG 796

Query: 581 RFVLARRHIVAAGFLIVDVPFYEW--LELKSEWQKGAYLKD 619
           +  + +RH+   G+ ++ +  +EW  + L ++  +  YL++
Sbjct: 797 KSAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRE 837


>gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo
           sapiens]
          Length = 549

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 85/324 (26%), Positives = 138/324 (42%), Gaps = 21/324 (6%)

Query: 314 QRLATDLLSLMPS-LTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLCSV 372
           Q L + L    P  LT   +   A+  A  +     L EA A  ++ +   ++   +  +
Sbjct: 221 QHLISSLAEARPEELTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQLSSKVVQKL 280

Query: 373 LLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQAREAELQAVLH 432
           +L F RLN+ P  E QF   +   L  E  G+ P   V+++ +LC L+      L  V  
Sbjct: 281 VLPFGRLNYLP-LEQQFMPCLERILAREA-GVAPLATVNILMSLCQLRCLPFRALHFVFS 338

Query: 433 PEFHIQFLGGKSQKDQNTFQKLLHINATAL-LEYPEYSGPLLPASA---VAPGPSALDRK 488
           P F I ++ G         ++ L +  TA+ LE P Y GP LP      + P P   DR 
Sbjct: 339 PGF-INYISGTPHA--LIVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRA 395

Query: 489 VTPLQKE--LQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVR--DFVAPH 544
                 +  + E L+ LLG  +K   ++    G+  D  +   S G  LPVR  D   P+
Sbjct: 396 RCKYSHKDIVAEGLRQLLGE-EKYRQDLTVPPGYCTDFLLCASSSGAVLPVRTQDPFLPY 454

Query: 545 ------LAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVD 598
                   Q   S +    ++R+  +  E  +F    + LLG   L  RH+   G+ ++ 
Sbjct: 455 PPRSCPQGQAASSATTRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLP 514

Query: 599 VPFYEWLELKSEWQKGAYLKDKMR 622
           +PF E    +   Q  +YL+ K++
Sbjct: 515 LPFEELESQRGLPQLKSYLRQKLQ 538


>gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Homo
           sapiens]
          Length = 408

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 85/324 (26%), Positives = 138/324 (42%), Gaps = 21/324 (6%)

Query: 314 QRLATDLLSLMPS-LTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLCSV 372
           Q L + L    P  LT   +   A+  A  +     L EA A  ++ +   ++   +  +
Sbjct: 80  QHLISSLAEARPEELTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQLSSKVVQKL 139

Query: 373 LLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQAREAELQAVLH 432
           +L F RLN+ P  E QF   +   L  E  G+ P   V+++ +LC L+      L  V  
Sbjct: 140 VLPFGRLNYLP-LEQQFMPCLERILAREA-GVAPLATVNILMSLCQLRCLPFRALHFVFS 197

Query: 433 PEFHIQFLGGKSQKDQNTFQKLLHINATAL-LEYPEYSGPLLPASA---VAPGPSALDRK 488
           P F I ++ G         ++ L +  TA+ LE P Y GP LP      + P P   DR 
Sbjct: 198 PGF-INYISGTPHA--LIVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRA 254

Query: 489 VTPLQKE--LQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVR--DFVAPH 544
                 +  + E L+ LLG  +K   ++    G+  D  +   S G  LPVR  D   P+
Sbjct: 255 RCKYSHKDIVAEGLRQLLGE-EKYRQDLTVPPGYCTDFLLCASSSGAVLPVRTQDPFLPY 313

Query: 545 ------LAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVD 598
                   Q   S +    ++R+  +  E  +F    + LLG   L  RH+   G+ ++ 
Sbjct: 314 PPRSCPQGQAASSATTRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLP 373

Query: 599 VPFYEWLELKSEWQKGAYLKDKMR 622
           +PF E    +   Q  +YL+ K++
Sbjct: 374 LPFEELESQRGLPQLKSYLRQKLQ 397


>gi|11141903 FAST kinase domains 5 [Homo sapiens]
          Length = 764

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 88/459 (19%), Positives = 178/459 (38%), Gaps = 17/459 (3%)

Query: 97  SNQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGT-LSKLLGSLYA 155
           +N  A V++     LS  P ++  ++  +    LLC L+ +   ++    L  +L +   
Sbjct: 156 NNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVI 215

Query: 156 LGIPKASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRW 215
           LGIP +   L   E +   ++ ++    L  +A+    L ++      L    ++L   W
Sbjct: 216 LGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKV--PRFLNIFSSYLNLHW 273

Query: 216 TEIEDSHT--LVTVMMKVGHLSEPLMNRLEDKCLELVEHFGPNELRKV-LVMLAAQSRRS 272
            ++  S    L+ V+ +   +S+ LM +LE   L+ ++     E+  + L    + +  S
Sbjct: 274 KDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLS 333

Query: 273 VPLLRAISYHLVQKPFSLTKDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEV 332
             ++R I          L+   L+++   +           +++       +PSL    V
Sbjct: 334 EFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGV 393

Query: 333 AHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSL 392
            H     + L++L+  +  A A  +  R        +  +L +F  LN+ P   ++F+S 
Sbjct: 394 MHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSS 453

Query: 393 VHEKLGSELPGLE--PALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNT 450
           +  ++  ++P     P      +  L  L+      +   L P F ++    +++ D   
Sbjct: 454 LISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGF-VRLAQERTKFD--L 510

Query: 451 FQKLLHINATALLEYPEYSGPLLPASAVAPGPSAL------DRKVTPLQKELQETLKGLL 504
            ++L  ++ T  +E P+Y G  L       G   L      D    P   E    L+ +L
Sbjct: 511 LKELYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETML 570

Query: 505 GSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDFVAP 543
           G        +   +    D EV LD + + LP      P
Sbjct: 571 GGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATP 609



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 17/49 (34%), Positives = 32/49 (65%), Gaps = 2/49 (4%)

Query: 575 SKDLLGRFVLARRHIVAAGFLIVDVPFYEWLEL--KSEWQKGAYLKDKM 621
           S+DLLG   + RR +   G+ +V++ ++EWL L  ++  +K A+L +K+
Sbjct: 711 SRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKV 759


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 36/178 (20%), Positives = 76/178 (42%), Gaps = 13/178 (7%)

Query: 201  QELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMNRLEDKCLELVEHFGPNELRK 260
            +EL+ E  +HLE+RW ++ED   L+   ++V   +   +N ++ +  EL+E     E + 
Sbjct: 4240 KELVKEQTSHLEQRWFQLED---LIKRKIQVSVTNLEELNVVQSRFQELME--WAEEQQP 4294

Query: 261  VLVMLAAQSRRSVPLLRAISYHL-----VQKPFSLTKDVLLDVAYAYGKLSFHQTQVSQR 315
             +     QS         +  HL     ++    L K ++ D       L  ++ QV Q+
Sbjct: 4295 NIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQK 4354

Query: 316  LATDL---LSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLC 370
              +D    ++ +  L      +  K+ +      + +F+A +Q   +  + +   H+C
Sbjct: 4355 ALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHIC 4412


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 36/178 (20%), Positives = 76/178 (42%), Gaps = 13/178 (7%)

Query: 201  QELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMNRLEDKCLELVEHFGPNELRK 260
            +EL+ E  +HLE+RW ++ED   L+   ++V   +   +N ++ +  EL+E     E + 
Sbjct: 4311 KELVKEQTSHLEQRWFQLED---LIKRKIQVSVTNLEELNVVQSRFQELME--WAEEQQP 4365

Query: 261  VLVMLAAQSRRSVPLLRAISYHL-----VQKPFSLTKDVLLDVAYAYGKLSFHQTQVSQR 315
             +     QS         +  HL     ++    L K ++ D       L  ++ QV Q+
Sbjct: 4366 NIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQK 4425

Query: 316  LATDL---LSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLC 370
              +D    ++ +  L      +  K+ +      + +F+A +Q   +  + +   H+C
Sbjct: 4426 ALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHIC 4483


>gi|239743173 PREDICTED: similar to solute carrier family 29
           (nucleoside transporters), member 4 [Homo sapiens]
          Length = 414

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 12/26 (46%), Positives = 16/26 (61%)

Query: 552 QSPPPGSKRLAFLRWEFPNFNSRSKD 577
           Q PPPG+ R+A LRW  P +  +  D
Sbjct: 5   QQPPPGAGRVADLRWRGPQYQIQHSD 30


>gi|239508837 PREDICTED: similar to solute carrier family 29
           (nucleoside transporters), member 4 [Homo sapiens]
          Length = 414

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 12/26 (46%), Positives = 16/26 (61%)

Query: 552 QSPPPGSKRLAFLRWEFPNFNSRSKD 577
           Q PPPG+ R+A LRW  P +  +  D
Sbjct: 5   QQPPPGAGRVADLRWRGPQYQIQHSD 30


>gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [Homo
           sapiens]
          Length = 482

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 9/94 (9%)

Query: 150 LGSLYALGIPKASKELQSVEQEVRWR-----MRKLKYKHLAFLAESCATLSQEQHSQELL 204
           LG +YA+ + + +K +++ +     R     +  +K+  +  LA +  T  +     E L
Sbjct: 92  LGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECL 151

Query: 205 A--ELLTHLERRWTEIEDS--HTLVTVMMKVGHL 234
           +  EL THLER    +ED+    L  + + +GHL
Sbjct: 152 SGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185


>gi|47578107 delangin isoform B [Homo sapiens]
          Length = 2697

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 38   TLTSSATSPISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDS 97
            TL+ S ++ +     S+++   KER S+P  E +     ++ +RP +  + +    D DS
Sbjct: 2456 TLSVSGSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDS 2515

Query: 98   NQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLL 134
                     ++ ++   PE+   LI+ A+  Q + LL
Sbjct: 2516 ED------DINSVMKCLPENSAPLIEFANVSQGILLL 2546


>gi|47578105 delangin isoform A [Homo sapiens]
          Length = 2804

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 6/97 (6%)

Query: 38   TLTSSATSPISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDS 97
            TL+ S ++ +     S+++   KER S+P  E +     ++ +RP +  + +    D DS
Sbjct: 2456 TLSVSGSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDS 2515

Query: 98   NQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLL 134
                     ++ ++   PE+   LI+ A+  Q + LL
Sbjct: 2516 ED------DINSVMKCLPENSAPLIEFANVSQGILLL 2546


>gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
          Length = 1318

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 15/145 (10%)

Query: 84  ELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWH 143
           + LE++ G+ D+          RL+     K  +   + QDA  + L+ +       V  
Sbjct: 147 QTLEMVIGASDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQ 206

Query: 144 GTLSKLLGS-------LYALGIPKASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQ 196
              ++LL         LY +G+  +S+EL S E +  W  + ++        +S   LS 
Sbjct: 207 HLETELLTGVFPHRSLLYVMGVLSSSEELFSQEDKACWEEQLIQ-----MAIKSVPFLST 261

Query: 197 EQHSQELLAELLTHLERRWTEIEDS 221
           +  S+ELL  L T     WT+ E S
Sbjct: 262 DVWSKELLWTLTT---PSWTQQEQS 283


>gi|239747159 PREDICTED: hypothetical protein XP_002343930 [Homo
           sapiens]
          Length = 278

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)

Query: 452 QKLLHINATALLEYPEYSGPLLPASAVAPGPSALDRKVTPLQ-KELQETLKG 502
           Q L  +   A   +P  S  L+PA+   PG SALDR+  P   +E+ ET+ G
Sbjct: 222 QTLYSMATQAAYVFPAESW-LVPATLPGPGESALDREAHPFPGQEITETVSG 272


>gi|27881506 ATP-binding cassette, sub-family F, member 2 isoform a
           [Homo sapiens]
          Length = 623

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 3/70 (4%)

Query: 46  PISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLI 105
           P    P   +  V+ ERA    +EK+ + L  +    E+L+EL     +LD+++A M   
Sbjct: 153 PSDKTPLHCVMEVDTERAM---LEKEAERLAHEDAECEKLMELYERLEELDADKAEMRAS 209

Query: 106 RLSHLLSEKP 115
           R+ H L   P
Sbjct: 210 RILHGLGFTP 219


>gi|10947137 ATP-binding cassette, sub-family F, member 2 isoform b
           [Homo sapiens]
          Length = 634

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 3/70 (4%)

Query: 46  PISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLI 105
           P    P   +  V+ ERA    +EK+ + L  +    E+L+EL     +LD+++A M   
Sbjct: 153 PSDKTPLHCVMEVDTERAM---LEKEAERLAHEDAECEKLMELYERLEELDADKAEMRAS 209

Query: 106 RLSHLLSEKP 115
           R+ H L   P
Sbjct: 210 RILHGLGFTP 219


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 9/80 (11%)

Query: 412 LVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSGP 471
           L W     Q+ARE + +  L  E        + QK  N+  +L H   T  +E P    P
Sbjct: 13  LEWQAQQQQRAREEQERLRLEQERE------QEQKKANSLARLAH---TLPVEEPRMEAP 63

Query: 472 LLPASAVAPGPSALDRKVTP 491
            LP S  AP P+      TP
Sbjct: 64  PLPLSPPAPPPAPPPPLATP 83


>gi|52353320 FSHD region gene 2 [Homo sapiens]
          Length = 278

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)

Query: 452 QKLLHINATALLEYPEYSGPLLPASAVAPGPSALDRKVTPLQ-KELQETLKG 502
           Q L  +   A   +P  S  L+PA+   PG SALDR+  P   +E+ ET+ G
Sbjct: 222 QTLYSMATQAAYVFPAESW-LVPATLPGPGESALDREAHPFPGQEITETVSG 272


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 83   EELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGLLI---QDAHFHQLLCLLNSQIA 139
            + L E+ G +    S    +    L+HLL+ +   +G  +   QDAHF++ L    S + 
Sbjct: 2210 QRLREVTGHTDHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLWAGSALL 2269

Query: 140  SVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLKYKHL 184
            +   G L   LG     G P ++  ++ +E+      R ++  +L
Sbjct: 2270 APETGDLWAALGQRAPGGSPGSAGLVRHLEEYAATLARNMELTYL 2314


>gi|50233787 nuclear protein in testis [Homo sapiens]
          Length = 1132

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 42/162 (25%), Positives = 62/162 (38%), Gaps = 30/162 (18%)

Query: 420 QQAREAELQAVLHPEFHIQFLGGKSQKDQ------------NTFQKLLHINATALLEY-- 465
           Q+   ++++AV+HP+F    L  + Q+D              T  +L+     AL E   
Sbjct: 420 QKVFVSKVEAVIHPQFLADLLSPEKQRDPLALIEELEQEEGLTLAQLVQKRLMALEEEED 479

Query: 466 ----PEYSGPLLPASAVAPGPSALD-------RKVTPLQKELQETLKGLLGSADKGSLEV 514
               P +SG  L +S   P  S  D       R    LQ        G + S+ K + EV
Sbjct: 480 AEAPPSFSGAQLDSS---PSGSVEDEDGDGRLRPSPGLQGAGGAACLGKVSSSGKRAREV 536

Query: 515 ATQYGWVLDAEVLLDSDGEFLPVRDF--VAPHLAQPTGSQSP 554
                  LD+   +  DG  LP      + P LA P G+  P
Sbjct: 537 HGGQEQALDSPRGMHRDGNTLPSPSSWDLQPELAAPQGTPGP 578


>gi|124487405 FSHD region gene 2 family, member B [Homo sapiens]
          Length = 278

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)

Query: 452 QKLLHINATALLEYPEYSGPLLPASAVAPGPSALDRKVTPLQ-KELQETLKG 502
           Q L  +   A   +P  S  L+PA+   PG SALDR+  P   +E+ ET+ G
Sbjct: 222 QTLYSMATQAAYVFPAESW-LVPATLPGPGESALDREAHPFPGQEITETVSG 272


>gi|118572603 ubinuclein 1 [Homo sapiens]
          Length = 1134

 Score = 30.0 bits (66), Expect = 6.7
 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%)

Query: 59  EKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVL-----IRLSHLLSE 113
           E +  + P  E Q    ++ A+ P  LL L G + D D  QAA  +     + L HLLSE
Sbjct: 265 EHKPVAVPSAEAQGLRELEGASDP--LLSLFGSTSDNDLLQAATAMDSLTDLDLEHLLSE 322

Query: 114 KPE 116
            PE
Sbjct: 323 SPE 325


>gi|118572601 ubinuclein 1 [Homo sapiens]
          Length = 1134

 Score = 30.0 bits (66), Expect = 6.7
 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%)

Query: 59  EKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVL-----IRLSHLLSE 113
           E +  + P  E Q    ++ A+ P  LL L G + D D  QAA  +     + L HLLSE
Sbjct: 265 EHKPVAVPSAEAQGLRELEGASDP--LLSLFGSTSDNDLLQAATAMDSLTDLDLEHLLSE 322

Query: 114 KPE 116
            PE
Sbjct: 323 SPE 325


>gi|13129124 caspase recruitment domain protein 14 isoform 1 [Homo
           sapiens]
          Length = 1004

 Score = 30.0 bits (66), Expect = 6.7
 Identities = 39/174 (22%), Positives = 69/174 (39%), Gaps = 21/174 (12%)

Query: 40  TSSATSPISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQ 99
           TS  T  ++   GSL E + +E+     + ++   L +     E   E   G H L+++ 
Sbjct: 121 TSKLTECLAGAIGSLQEELNQEKGQKEVLLRRCQQLQEHLGLAETRAE---GLHQLEADH 177

Query: 100 AAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIP 159
           + M           K E        AHFH++L L +  ++   H + +     L A    
Sbjct: 178 SRM-----------KRE------VSAHFHEVLRLKDEMLSLSLHYSNALQEKELAASRCR 220

Query: 160 KASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLER 213
              +EL  ++QE++ R   +    L    +S  T S ++   E L  L    E+
Sbjct: 221 SLQEELYLLKQELQ-RANMVSSCELELQEQSLRTASDQESGDEELNRLKEENEK 273


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,345,836
Number of Sequences: 37866
Number of extensions: 1087116
Number of successful extensions: 3264
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3219
Number of HSP's gapped (non-prelim): 54
length of query: 631
length of database: 18,247,518
effective HSP length: 108
effective length of query: 523
effective length of database: 14,157,990
effective search space: 7404628770
effective search space used: 7404628770
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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