BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|40217812 cell cycle progression 2 protein isoform 1 [Homo sapiens] (631 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|40217812 cell cycle progression 2 protein isoform 1 [Homo sap... 1249 0.0 gi|40217810 cell cycle progression 2 protein isoform 2 [Homo sap... 561 e-160 gi|13569848 cell cycle progression 2 protein isoform 2 [Homo sap... 561 e-160 gi|40068497 FAST kinase domains 3 [Homo sapiens] 117 4e-26 gi|209969832 FAST kinase domains 2 [Homo sapiens] 76 1e-13 gi|209969830 FAST kinase domains 2 [Homo sapiens] 76 1e-13 gi|45267832 FAST kinase domains 2 [Homo sapiens] 76 1e-13 gi|188497683 FAST kinase domains 1 [Homo sapiens] 69 1e-11 gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo... 69 1e-11 gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Hom... 69 1e-11 gi|11141903 FAST kinase domains 5 [Homo sapiens] 51 4e-06 gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 32 1.8 gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 32 1.8 gi|239743173 PREDICTED: similar to solute carrier family 29 (nuc... 31 3.0 gi|239508837 PREDICTED: similar to solute carrier family 29 (nuc... 31 3.0 gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [H... 31 4.0 gi|47578107 delangin isoform B [Homo sapiens] 31 4.0 gi|47578105 delangin isoform A [Homo sapiens] 31 4.0 gi|148727311 hypothetical protein LOC389690 [Homo sapiens] 31 4.0 gi|239747159 PREDICTED: hypothetical protein XP_002343930 [Homo ... 30 5.2 gi|27881506 ATP-binding cassette, sub-family F, member 2 isoform... 30 5.2 gi|10947137 ATP-binding cassette, sub-family F, member 2 isoform... 30 5.2 gi|9945318 MAX binding protein [Homo sapiens] 30 5.2 gi|52353320 FSHD region gene 2 [Homo sapiens] 30 5.2 gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 30 5.2 gi|50233787 nuclear protein in testis [Homo sapiens] 30 5.2 gi|124487405 FSHD region gene 2 family, member B [Homo sapiens] 30 5.2 gi|118572603 ubinuclein 1 [Homo sapiens] 30 6.7 gi|118572601 ubinuclein 1 [Homo sapiens] 30 6.7 gi|13129124 caspase recruitment domain protein 14 isoform 1 [Hom... 30 6.7 >gi|40217812 cell cycle progression 2 protein isoform 1 [Homo sapiens] Length = 631 Score = 1249 bits (3231), Expect = 0.0 Identities = 631/631 (100%), Positives = 631/631 (100%) Query: 1 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK Sbjct: 1 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60 Query: 61 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL Sbjct: 61 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120 Query: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK Sbjct: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180 Query: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN Sbjct: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240 Query: 241 RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY 300 RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY Sbjct: 241 RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY 300 Query: 301 AYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNR 360 AYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNR Sbjct: 301 AYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNR 360 Query: 361 AQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQ 420 AQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQ Sbjct: 361 AQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQ 420 Query: 421 QAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSGPLLPASAVAP 480 QAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSGPLLPASAVAP Sbjct: 421 QAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSGPLLPASAVAP 480 Query: 481 GPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDF 540 GPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDF Sbjct: 481 GPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDF 540 Query: 541 VAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVP 600 VAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVP Sbjct: 541 VAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVP 600 Query: 601 FYEWLELKSEWQKGAYLKDKMRKAVAEELAK 631 FYEWLELKSEWQKGAYLKDKMRKAVAEELAK Sbjct: 601 FYEWLELKSEWQKGAYLKDKMRKAVAEELAK 631 >gi|40217810 cell cycle progression 2 protein isoform 2 [Homo sapiens] Length = 521 Score = 561 bits (1446), Expect = e-160 Identities = 317/467 (67%), Positives = 350/467 (74%), Gaps = 32/467 (6%) Query: 194 LSQEQHSQELLAELLTHLERRWTEIE------------DSHTLVTVMMKVGHLSEPLMNR 241 + +E+ S + + + HL ++ T E DS+ V++++ HL L + Sbjct: 58 VEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHL---LSEK 114 Query: 242 LEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHL-VQKPFSLTKDVLLDVAY 300 EDK L + + L + +A+ ++ L Y L + K + V +V + Sbjct: 115 PEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRW 174 Query: 301 AYGKLSFH-------------QTQVSQRLATDLLS-LMPSLTSGEVAHCAKSFAL-LKWL 345 KL + Q Q SQ L +LL+ L T E +H + + + L Sbjct: 175 RMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHL 234 Query: 346 SLPLFEAFA-QHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL 404 S PL +HVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL Sbjct: 235 SEPLMNRLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL 294 Query: 405 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE 464 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE Sbjct: 295 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE 354 Query: 465 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA 524 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA Sbjct: 355 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA 414 Query: 525 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL 584 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL Sbjct: 415 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL 474 Query: 585 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 631 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK Sbjct: 475 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 521 Score = 488 bits (1257), Expect = e-138 Identities = 260/334 (77%), Positives = 272/334 (81%), Gaps = 43/334 (12%) Query: 1 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK Sbjct: 1 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60 Query: 61 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL Sbjct: 61 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120 Query: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK Sbjct: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180 Query: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN Sbjct: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240 Query: 241 RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY 300 RLEDK H++ + +T L V Sbjct: 241 RLEDK------------------------------------HVLNRAQDITLPHLCSVLL 264 Query: 301 AYGKLSFHQTQ-------VSQRLATDLLSLMPSL 327 A+ +L+FH Q V ++L ++L L P+L Sbjct: 265 AFARLNFHPDQEDQFFSLVHEKLGSELPGLEPAL 298 >gi|13569848 cell cycle progression 2 protein isoform 2 [Homo sapiens] Length = 521 Score = 561 bits (1446), Expect = e-160 Identities = 317/467 (67%), Positives = 350/467 (74%), Gaps = 32/467 (6%) Query: 194 LSQEQHSQELLAELLTHLERRWTEIE------------DSHTLVTVMMKVGHLSEPLMNR 241 + +E+ S + + + HL ++ T E DS+ V++++ HL L + Sbjct: 58 VEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHL---LSEK 114 Query: 242 LEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHL-VQKPFSLTKDVLLDVAY 300 EDK L + + L + +A+ ++ L Y L + K + V +V + Sbjct: 115 PEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRW 174 Query: 301 AYGKLSFH-------------QTQVSQRLATDLLS-LMPSLTSGEVAHCAKSFAL-LKWL 345 KL + Q Q SQ L +LL+ L T E +H + + + L Sbjct: 175 RMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHL 234 Query: 346 SLPLFEAFA-QHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL 404 S PL +HVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL Sbjct: 235 SEPLMNRLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGL 294 Query: 405 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE 464 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE Sbjct: 295 EPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLE 354 Query: 465 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA 524 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA Sbjct: 355 YPEYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDA 414 Query: 525 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL 584 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL Sbjct: 415 EVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVL 474 Query: 585 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 631 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK Sbjct: 475 ARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 521 Score = 488 bits (1257), Expect = e-138 Identities = 260/334 (77%), Positives = 272/334 (81%), Gaps = 43/334 (12%) Query: 1 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK Sbjct: 1 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 60 Query: 61 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL Sbjct: 61 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 120 Query: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK Sbjct: 121 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 180 Query: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN Sbjct: 181 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 240 Query: 241 RLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLTKDVLLDVAY 300 RLEDK H++ + +T L V Sbjct: 241 RLEDK------------------------------------HVLNRAQDITLPHLCSVLL 264 Query: 301 AYGKLSFHQTQ-------VSQRLATDLLSLMPSL 327 A+ +L+FH Q V ++L ++L L P+L Sbjct: 265 AFARLNFHPDQEDQFFSLVHEKLGSELPGLEPAL 298 >gi|40068497 FAST kinase domains 3 [Homo sapiens] Length = 662 Score = 117 bits (292), Expect = 4e-26 Identities = 134/567 (23%), Positives = 244/567 (43%), Gaps = 42/567 (7%) Query: 76 IKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL---LIQDAHFHQLLC 132 + T EE+L + L AA L R+ + +K D+GL +++++ F L Sbjct: 106 LSNLTSSEEVLSFISTMETLPDTMAAGALQRICEV-EKKDGDQGLPKEILENSIFQALCF 164 Query: 133 LLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRK--LKYKHLAFLAES 190 + + + + +L L +L L + S L ++ E + R+RK ++ ++L L ES Sbjct: 165 QFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLVAECQNRLRKGGMEVRNLCILGES 224 Query: 191 CATL-SQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMM----KVGHLSEPLMNRLEDK 245 TL S + EL+ L + ED L ++ KV + +N++ + Sbjct: 225 LITLHSSGCVTLELIINQLQGEKLETFTPEDIVALYRILQACTEKVDE-HQTFLNKINNF 283 Query: 246 CLELVEHFGPNELRKVLVMLAAQSR-RSVPLLRAISYHLVQKPFSLTKDVLLDVAYAYGK 304 L +V + P + ++L L + ++ PL+ + ++V+ T + L V A+ Sbjct: 284 SLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIY 343 Query: 305 LSFHQT----QVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNR 360 H T + R+A L+L P + + +C++ L K P+ A A+ + + Sbjct: 344 FGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSRELILSK----PILNAVAETFVCQ 399 Query: 361 AQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQ 420 + + + +++ F +LN+ P F + L + P + L+ + C L Sbjct: 400 TEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHS-CSLN 458 Query: 421 QAREAELQAVLHPEFHIQFLGGK-SQKDQNTFQKLLHINATALLEYPEYSGP-LLPASAV 478 + A + +Q L GK S D + +L + ++LE P Y GP LLP V Sbjct: 459 ECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASVLECPFYKGPKLLPKYQV 518 Query: 479 APGPSALDRKVTPLQKELQETLK----GLLGSADKGSLEVATQYGWVLDAEVLLDSDGEF 534 + TP+ +L +K LLG+ + +V T Y + +D E+ LD +G Sbjct: 519 KSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFV 578 Query: 535 LPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGF 594 LP S + KR+A F S SK LLG+ + +RH+ G+ Sbjct: 579 LP--------------STANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGY 624 Query: 595 LIVDVPFYEWLELKSEWQKGAYLKDKM 621 +V +P++E LKS + YL+ K+ Sbjct: 625 QVVQIPYHEIGMLKSRRELVEYLQRKL 651 >gi|209969832 FAST kinase domains 2 [Homo sapiens] Length = 710 Score = 75.9 bits (185), Expect = 1e-13 Identities = 104/525 (19%), Positives = 217/525 (41%), Gaps = 28/525 (5%) Query: 113 EKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEV 172 +K +K L+ F+QL + + + + L L ++ LGIP+ + +Q++ + Sbjct: 199 QKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVT 258 Query: 173 RWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVG 232 + R+ + L+ L+ + ++ L ++++ +IED TL VM +G Sbjct: 259 QERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVVMKCIG 318 Query: 233 HLSE-PLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLT 291 + L +LE K L ++ F + + +LAA + RS+ LL S ++ Sbjct: 319 KDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNIHGCP 378 Query: 292 KDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFE 351 +++++ + L +H + + LA + + +V F L + + L + Sbjct: 379 LRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGLMD 438 Query: 352 AFAQHVLNRAQDITLPHLCSVLLAFARLN--FHPDQEDQFFSLVHEKLGSELPGLEPALQ 409 F + ++ + + + ++ S+L ++ LN + ++QF ++ L L + Sbjct: 439 LFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENL 498 Query: 410 VDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQ---NTFQKLLHINATALLEYP 466 +D V++ C++ A +L + + L K+ +T L ++ T L Sbjct: 499 LDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDI 558 Query: 467 EYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEV 526 S P LP + +A ++ E L LLG S +V + + +D E+ Sbjct: 559 ALSLPQLPRELPSSHTNA----------KVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEI 608 Query: 527 LLDSD-GEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLA 585 +D++ + LP+ D + +R+A L + S G + Sbjct: 609 RMDTNRNQVLPLSDV----------DTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMK 658 Query: 586 RRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELA 630 RH+ A GF ++ V +E +L+ E +LK K+ A +A Sbjct: 659 MRHLNAMGFHVILVNNWEMDKLEME-DAVTFLKTKIYSVEALPVA 702 >gi|209969830 FAST kinase domains 2 [Homo sapiens] Length = 710 Score = 75.9 bits (185), Expect = 1e-13 Identities = 104/525 (19%), Positives = 217/525 (41%), Gaps = 28/525 (5%) Query: 113 EKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEV 172 +K +K L+ F+QL + + + + L L ++ LGIP+ + +Q++ + Sbjct: 199 QKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVT 258 Query: 173 RWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVG 232 + R+ + L+ L+ + ++ L ++++ +IED TL VM +G Sbjct: 259 QERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVVMKCIG 318 Query: 233 HLSE-PLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLT 291 + L +LE K L ++ F + + +LAA + RS+ LL S ++ Sbjct: 319 KDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNIHGCP 378 Query: 292 KDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFE 351 +++++ + L +H + + LA + + +V F L + + L + Sbjct: 379 LRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGLMD 438 Query: 352 AFAQHVLNRAQDITLPHLCSVLLAFARLN--FHPDQEDQFFSLVHEKLGSELPGLEPALQ 409 F + ++ + + + ++ S+L ++ LN + ++QF ++ L L + Sbjct: 439 LFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENL 498 Query: 410 VDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQ---NTFQKLLHINATALLEYP 466 +D V++ C++ A +L + + L K+ +T L ++ T L Sbjct: 499 LDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDI 558 Query: 467 EYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEV 526 S P LP + +A ++ E L LLG S +V + + +D E+ Sbjct: 559 ALSLPQLPRELPSSHTNA----------KVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEI 608 Query: 527 LLDSD-GEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLA 585 +D++ + LP+ D + +R+A L + S G + Sbjct: 609 RMDTNRNQVLPLSDV----------DTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMK 658 Query: 586 RRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELA 630 RH+ A GF ++ V +E +L+ E +LK K+ A +A Sbjct: 659 MRHLNAMGFHVILVNNWEMDKLEME-DAVTFLKTKIYSVEALPVA 702 >gi|45267832 FAST kinase domains 2 [Homo sapiens] Length = 710 Score = 75.9 bits (185), Expect = 1e-13 Identities = 104/525 (19%), Positives = 217/525 (41%), Gaps = 28/525 (5%) Query: 113 EKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEV 172 +K +K L+ F+QL + + + + L L ++ LGIP+ + +Q++ + Sbjct: 199 QKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVT 258 Query: 173 RWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVG 232 + R+ + L+ L+ + ++ L ++++ +IED TL VM +G Sbjct: 259 QERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVVMKCIG 318 Query: 233 HLSE-PLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLT 291 + L +LE K L ++ F + + +LAA + RS+ LL S ++ Sbjct: 319 KDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNIHGCP 378 Query: 292 KDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFE 351 +++++ + L +H + + LA + + +V F L + + L + Sbjct: 379 LRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGLMD 438 Query: 352 AFAQHVLNRAQDITLPHLCSVLLAFARLN--FHPDQEDQFFSLVHEKLGSELPGLEPALQ 409 F + ++ + + + ++ S+L ++ LN + ++QF ++ L L + Sbjct: 439 LFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENL 498 Query: 410 VDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQ---NTFQKLLHINATALLEYP 466 +D V++ C++ A +L + + L K+ +T L ++ T L Sbjct: 499 LDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDI 558 Query: 467 EYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEV 526 S P LP + +A ++ E L LLG S +V + + +D E+ Sbjct: 559 ALSLPQLPRELPSSHTNA----------KVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEI 608 Query: 527 LLDSD-GEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLA 585 +D++ + LP+ D + +R+A L + S G + Sbjct: 609 RMDTNRNQVLPLSDV----------DTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMK 658 Query: 586 RRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELA 630 RH+ A GF ++ V +E +L+ E +LK K+ A +A Sbjct: 659 MRHLNAMGFHVILVNNWEMDKLEME-DAVTFLKTKIYSVEALPVA 702 >gi|188497683 FAST kinase domains 1 [Homo sapiens] Length = 847 Score = 69.3 bits (168), Expect = 1e-11 Identities = 112/521 (21%), Positives = 225/521 (43%), Gaps = 62/521 (11%) Query: 146 LSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLKYKHL-AFLAESCATLSQEQ-----H 199 +S+ L AL + A +++S + R+ + +KHL + ++QE Sbjct: 332 MSEDLTGEQALAVLGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQELTFLHFQ 391 Query: 200 SQELLAEL----LTHLERRWTEIEDSHTLVTV-MMKVGHLSEPLMNRLE---DKC-LELV 250 +E A+L L++L+ + E S + + ++ HL E ++R+E +C L + Sbjct: 392 RKEFFAKLRELLLSYLKNSFIPTEVSVLVRAISLLPSPHLDEVGISRIEAVLPQCDLNNL 451 Query: 251 EHFGPNELRKVL---VMLAAQSRRSVPLLRAISYHLVQK-PFSLTKDVLLDVAYAYGKLS 306 F + LR + + L + + + LL+ + ++ Q+ S + D+L + + Sbjct: 452 SSFATSVLRWIQHDHMYLDNMTAKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNT 511 Query: 307 FHQTQVSQRLAT--DLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDI 364 F ++ + + +AT + + + GE+A S L L L + A + + Sbjct: 512 FPESLLEEMIATLQHFMDDINYINVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPF 571 Query: 365 TLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQARE 424 T+P +++ F+ LN+ P Q D+F + L S L L+P + V L ++L L+ E Sbjct: 572 TIP---AIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPE 628 Query: 425 AELQAVLHPEFHIQFLG---------GKSQKDQNTFQKLLHINATALLEYPEYSGPLLP- 474 L+A+ F+I+FL S+ + F L+ +N + LE PE+ P Sbjct: 629 DLLKAI----FNIKFLARLDSQLEILSPSRSARVQFH-LMELNRSVCLECPEFQIPWFHD 683 Query: 475 --ASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDG 532 G +D Q+++ + L +LG + V T Y +D E +LD Sbjct: 684 RFCQQYNKGIGGMD----GTQQQIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKRK 739 Query: 533 EFLPVRDFVAPHLAQPTGSQSP------------PPGSKRLAFLRWEFPNFNSRSKDLLG 580 + LP + + ++A + P PPG++R+A + + G Sbjct: 740 KPLP---YGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALEFLDSKALCRNIPHMKG 796 Query: 581 RFVLARRHIVAAGFLIVDVPFYEW--LELKSEWQKGAYLKD 619 + + +RH+ G+ ++ + +EW + L ++ + YL++ Sbjct: 797 KSAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRE 837 >gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo sapiens] Length = 549 Score = 68.9 bits (167), Expect = 1e-11 Identities = 85/324 (26%), Positives = 138/324 (42%), Gaps = 21/324 (6%) Query: 314 QRLATDLLSLMPS-LTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLCSV 372 Q L + L P LT + A+ A + L EA A ++ + ++ + + Sbjct: 221 QHLISSLAEARPEELTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQLSSKVVQKL 280 Query: 373 LLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQAREAELQAVLH 432 +L F RLN+ P E QF + L E G+ P V+++ +LC L+ L V Sbjct: 281 VLPFGRLNYLP-LEQQFMPCLERILAREA-GVAPLATVNILMSLCQLRCLPFRALHFVFS 338 Query: 433 PEFHIQFLGGKSQKDQNTFQKLLHINATAL-LEYPEYSGPLLPASA---VAPGPSALDRK 488 P F I ++ G ++ L + TA+ LE P Y GP LP + P P DR Sbjct: 339 PGF-INYISGTPHA--LIVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRA 395 Query: 489 VTPLQKE--LQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVR--DFVAPH 544 + + E L+ LLG +K ++ G+ D + S G LPVR D P+ Sbjct: 396 RCKYSHKDIVAEGLRQLLGE-EKYRQDLTVPPGYCTDFLLCASSSGAVLPVRTQDPFLPY 454 Query: 545 ------LAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVD 598 Q S + ++R+ + E +F + LLG L RH+ G+ ++ Sbjct: 455 PPRSCPQGQAASSATTRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLP 514 Query: 599 VPFYEWLELKSEWQKGAYLKDKMR 622 +PF E + Q +YL+ K++ Sbjct: 515 LPFEELESQRGLPQLKSYLRQKLQ 538 >gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Homo sapiens] Length = 408 Score = 68.9 bits (167), Expect = 1e-11 Identities = 85/324 (26%), Positives = 138/324 (42%), Gaps = 21/324 (6%) Query: 314 QRLATDLLSLMPS-LTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLCSV 372 Q L + L P LT + A+ A + L EA A ++ + ++ + + Sbjct: 80 QHLISSLAEARPEELTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQLSSKVVQKL 139 Query: 373 LLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQAREAELQAVLH 432 +L F RLN+ P E QF + L E G+ P V+++ +LC L+ L V Sbjct: 140 VLPFGRLNYLP-LEQQFMPCLERILAREA-GVAPLATVNILMSLCQLRCLPFRALHFVFS 197 Query: 433 PEFHIQFLGGKSQKDQNTFQKLLHINATAL-LEYPEYSGPLLPASA---VAPGPSALDRK 488 P F I ++ G ++ L + TA+ LE P Y GP LP + P P DR Sbjct: 198 PGF-INYISGTPHA--LIVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRA 254 Query: 489 VTPLQKE--LQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVR--DFVAPH 544 + + E L+ LLG +K ++ G+ D + S G LPVR D P+ Sbjct: 255 RCKYSHKDIVAEGLRQLLGE-EKYRQDLTVPPGYCTDFLLCASSSGAVLPVRTQDPFLPY 313 Query: 545 ------LAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVD 598 Q S + ++R+ + E +F + LLG L RH+ G+ ++ Sbjct: 314 PPRSCPQGQAASSATTRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLP 373 Query: 599 VPFYEWLELKSEWQKGAYLKDKMR 622 +PF E + Q +YL+ K++ Sbjct: 374 LPFEELESQRGLPQLKSYLRQKLQ 397 >gi|11141903 FAST kinase domains 5 [Homo sapiens] Length = 764 Score = 50.8 bits (120), Expect = 4e-06 Identities = 88/459 (19%), Positives = 178/459 (38%), Gaps = 17/459 (3%) Query: 97 SNQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGT-LSKLLGSLYA 155 +N A V++ LS P ++ ++ + LLC L+ + ++ L +L + Sbjct: 156 NNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVI 215 Query: 156 LGIPKASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRW 215 LGIP + L E + ++ ++ L +A+ L ++ L ++L W Sbjct: 216 LGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKV--PRFLNIFSSYLNLHW 273 Query: 216 TEIEDSHT--LVTVMMKVGHLSEPLMNRLEDKCLELVEHFGPNELRKV-LVMLAAQSRRS 272 ++ S L+ V+ + +S+ LM +LE L+ ++ E+ + L + + S Sbjct: 274 KDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLS 333 Query: 273 VPLLRAISYHLVQKPFSLTKDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEV 332 ++R I L+ L+++ + +++ +PSL V Sbjct: 334 EFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGV 393 Query: 333 AHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSL 392 H + L++L+ + A A + R + +L +F LN+ P ++F+S Sbjct: 394 MHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSS 453 Query: 393 VHEKLGSELPGLE--PALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNT 450 + ++ ++P P + L L+ + L P F ++ +++ D Sbjct: 454 LISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGF-VRLAQERTKFD--L 510 Query: 451 FQKLLHINATALLEYPEYSGPLLPASAVAPGPSAL------DRKVTPLQKELQETLKGLL 504 ++L ++ T +E P+Y G L G L D P E L+ +L Sbjct: 511 LKELYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETML 570 Query: 505 GSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDFVAP 543 G + + D EV LD + + LP P Sbjct: 571 GGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATP 609 Score = 37.0 bits (84), Expect = 0.055 Identities = 17/49 (34%), Positives = 32/49 (65%), Gaps = 2/49 (4%) Query: 575 SKDLLGRFVLARRHIVAAGFLIVDVPFYEWLEL--KSEWQKGAYLKDKM 621 S+DLLG + RR + G+ +V++ ++EWL L ++ +K A+L +K+ Sbjct: 711 SRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKV 759 >gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2 [Homo sapiens] Length = 8749 Score = 32.0 bits (71), Expect = 1.8 Identities = 36/178 (20%), Positives = 76/178 (42%), Gaps = 13/178 (7%) Query: 201 QELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMNRLEDKCLELVEHFGPNELRK 260 +EL+ E +HLE+RW ++ED L+ ++V + +N ++ + EL+E E + Sbjct: 4240 KELVKEQTSHLEQRWFQLED---LIKRKIQVSVTNLEELNVVQSRFQELME--WAEEQQP 4294 Query: 261 VLVMLAAQSRRSVPLLRAISYHL-----VQKPFSLTKDVLLDVAYAYGKLSFHQTQVSQR 315 + QS + HL ++ L K ++ D L ++ QV Q+ Sbjct: 4295 NIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQK 4354 Query: 316 LATDL---LSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLC 370 +D ++ + L + K+ + + +F+A +Q + + + H+C Sbjct: 4355 ALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHIC 4412 >gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1 [Homo sapiens] Length = 8797 Score = 32.0 bits (71), Expect = 1.8 Identities = 36/178 (20%), Positives = 76/178 (42%), Gaps = 13/178 (7%) Query: 201 QELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMNRLEDKCLELVEHFGPNELRK 260 +EL+ E +HLE+RW ++ED L+ ++V + +N ++ + EL+E E + Sbjct: 4311 KELVKEQTSHLEQRWFQLED---LIKRKIQVSVTNLEELNVVQSRFQELME--WAEEQQP 4365 Query: 261 VLVMLAAQSRRSVPLLRAISYHL-----VQKPFSLTKDVLLDVAYAYGKLSFHQTQVSQR 315 + QS + HL ++ L K ++ D L ++ QV Q+ Sbjct: 4366 NIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQK 4425 Query: 316 LATDL---LSLMPSLTSGEVAHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLC 370 +D ++ + L + K+ + + +F+A +Q + + + H+C Sbjct: 4426 ALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHIC 4483 >gi|239743173 PREDICTED: similar to solute carrier family 29 (nucleoside transporters), member 4 [Homo sapiens] Length = 414 Score = 31.2 bits (69), Expect = 3.0 Identities = 12/26 (46%), Positives = 16/26 (61%) Query: 552 QSPPPGSKRLAFLRWEFPNFNSRSKD 577 Q PPPG+ R+A LRW P + + D Sbjct: 5 QQPPPGAGRVADLRWRGPQYQIQHSD 30 >gi|239508837 PREDICTED: similar to solute carrier family 29 (nucleoside transporters), member 4 [Homo sapiens] Length = 414 Score = 31.2 bits (69), Expect = 3.0 Identities = 12/26 (46%), Positives = 16/26 (61%) Query: 552 QSPPPGSKRLAFLRWEFPNFNSRSKD 577 Q PPPG+ R+A LRW P + + D Sbjct: 5 QQPPPGAGRVADLRWRGPQYQIQHSD 30 >gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [Homo sapiens] Length = 482 Score = 30.8 bits (68), Expect = 4.0 Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 9/94 (9%) Query: 150 LGSLYALGIPKASKELQSVEQEVRWR-----MRKLKYKHLAFLAESCATLSQEQHSQELL 204 LG +YA+ + + +K +++ + R + +K+ + LA + T + E L Sbjct: 92 LGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECL 151 Query: 205 A--ELLTHLERRWTEIEDS--HTLVTVMMKVGHL 234 + EL THLER +ED+ L + + +GHL Sbjct: 152 SGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185 >gi|47578107 delangin isoform B [Homo sapiens] Length = 2697 Score = 30.8 bits (68), Expect = 4.0 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 6/97 (6%) Query: 38 TLTSSATSPISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDS 97 TL+ S ++ + S+++ KER S+P E + ++ +RP + + + D DS Sbjct: 2456 TLSVSGSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDS 2515 Query: 98 NQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLL 134 ++ ++ PE+ LI+ A+ Q + LL Sbjct: 2516 ED------DINSVMKCLPENSAPLIEFANVSQGILLL 2546 >gi|47578105 delangin isoform A [Homo sapiens] Length = 2804 Score = 30.8 bits (68), Expect = 4.0 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 6/97 (6%) Query: 38 TLTSSATSPISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDS 97 TL+ S ++ + S+++ KER S+P E + ++ +RP + + + D DS Sbjct: 2456 TLSVSGSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDS 2515 Query: 98 NQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLL 134 ++ ++ PE+ LI+ A+ Q + LL Sbjct: 2516 ED------DINSVMKCLPENSAPLIEFANVSQGILLL 2546 >gi|148727311 hypothetical protein LOC389690 [Homo sapiens] Length = 1318 Score = 30.8 bits (68), Expect = 4.0 Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 15/145 (10%) Query: 84 ELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWH 143 + LE++ G+ D+ RL+ K + + QDA + L+ + V Sbjct: 147 QTLEMVIGASDVLEETWEKTFTRLALENMTKATELEDIYQDAASNMLVAICRHSWRVVAQ 206 Query: 144 GTLSKLLGS-------LYALGIPKASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQ 196 ++LL LY +G+ +S+EL S E + W + ++ +S LS Sbjct: 207 HLETELLTGVFPHRSLLYVMGVLSSSEELFSQEDKACWEEQLIQ-----MAIKSVPFLST 261 Query: 197 EQHSQELLAELLTHLERRWTEIEDS 221 + S+ELL L T WT+ E S Sbjct: 262 DVWSKELLWTLTT---PSWTQQEQS 283 >gi|239747159 PREDICTED: hypothetical protein XP_002343930 [Homo sapiens] Length = 278 Score = 30.4 bits (67), Expect = 5.2 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 452 QKLLHINATALLEYPEYSGPLLPASAVAPGPSALDRKVTPLQ-KELQETLKG 502 Q L + A +P S L+PA+ PG SALDR+ P +E+ ET+ G Sbjct: 222 QTLYSMATQAAYVFPAESW-LVPATLPGPGESALDREAHPFPGQEITETVSG 272 >gi|27881506 ATP-binding cassette, sub-family F, member 2 isoform a [Homo sapiens] Length = 623 Score = 30.4 bits (67), Expect = 5.2 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Query: 46 PISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLI 105 P P + V+ ERA +EK+ + L + E+L+EL +LD+++A M Sbjct: 153 PSDKTPLHCVMEVDTERAM---LEKEAERLAHEDAECEKLMELYERLEELDADKAEMRAS 209 Query: 106 RLSHLLSEKP 115 R+ H L P Sbjct: 210 RILHGLGFTP 219 >gi|10947137 ATP-binding cassette, sub-family F, member 2 isoform b [Homo sapiens] Length = 634 Score = 30.4 bits (67), Expect = 5.2 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Query: 46 PISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLI 105 P P + V+ ERA +EK+ + L + E+L+EL +LD+++A M Sbjct: 153 PSDKTPLHCVMEVDTERAM---LEKEAERLAHEDAECEKLMELYERLEELDADKAEMRAS 209 Query: 106 RLSHLLSEKP 115 R+ H L P Sbjct: 210 RILHGLGFTP 219 >gi|9945318 MAX binding protein [Homo sapiens] Length = 582 Score = 30.4 bits (67), Expect = 5.2 Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Query: 412 LVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSGP 471 L W Q+ARE + + L E + QK N+ +L H T +E P P Sbjct: 13 LEWQAQQQQRAREEQERLRLEQERE------QEQKKANSLARLAH---TLPVEEPRMEAP 63 Query: 472 LLPASAVAPGPSALDRKVTP 491 LP S AP P+ TP Sbjct: 64 PLPLSPPAPPPAPPPPLATP 83 >gi|52353320 FSHD region gene 2 [Homo sapiens] Length = 278 Score = 30.4 bits (67), Expect = 5.2 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 452 QKLLHINATALLEYPEYSGPLLPASAVAPGPSALDRKVTPLQ-KELQETLKG 502 Q L + A +P S L+PA+ PG SALDR+ P +E+ ET+ G Sbjct: 222 QTLYSMATQAAYVFPAESW-LVPATLPGPGESALDREAHPFPGQEITETVSG 272 >gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo sapiens] Length = 3312 Score = 30.4 bits (67), Expect = 5.2 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 3/105 (2%) Query: 83 EELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGLLI---QDAHFHQLLCLLNSQIA 139 + L E+ G + S + L+HLL+ + +G + QDAHF++ L S + Sbjct: 2210 QRLREVTGHTDHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLWAGSALL 2269 Query: 140 SVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLKYKHL 184 + G L LG G P ++ ++ +E+ R ++ +L Sbjct: 2270 APETGDLWAALGQRAPGGSPGSAGLVRHLEEYAATLARNMELTYL 2314 >gi|50233787 nuclear protein in testis [Homo sapiens] Length = 1132 Score = 30.4 bits (67), Expect = 5.2 Identities = 42/162 (25%), Positives = 62/162 (38%), Gaps = 30/162 (18%) Query: 420 QQAREAELQAVLHPEFHIQFLGGKSQKDQ------------NTFQKLLHINATALLEY-- 465 Q+ ++++AV+HP+F L + Q+D T +L+ AL E Sbjct: 420 QKVFVSKVEAVIHPQFLADLLSPEKQRDPLALIEELEQEEGLTLAQLVQKRLMALEEEED 479 Query: 466 ----PEYSGPLLPASAVAPGPSALD-------RKVTPLQKELQETLKGLLGSADKGSLEV 514 P +SG L +S P S D R LQ G + S+ K + EV Sbjct: 480 AEAPPSFSGAQLDSS---PSGSVEDEDGDGRLRPSPGLQGAGGAACLGKVSSSGKRAREV 536 Query: 515 ATQYGWVLDAEVLLDSDGEFLPVRDF--VAPHLAQPTGSQSP 554 LD+ + DG LP + P LA P G+ P Sbjct: 537 HGGQEQALDSPRGMHRDGNTLPSPSSWDLQPELAAPQGTPGP 578 >gi|124487405 FSHD region gene 2 family, member B [Homo sapiens] Length = 278 Score = 30.4 bits (67), Expect = 5.2 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 452 QKLLHINATALLEYPEYSGPLLPASAVAPGPSALDRKVTPLQ-KELQETLKG 502 Q L + A +P S L+PA+ PG SALDR+ P +E+ ET+ G Sbjct: 222 QTLYSMATQAAYVFPAESW-LVPATLPGPGESALDREAHPFPGQEITETVSG 272 >gi|118572603 ubinuclein 1 [Homo sapiens] Length = 1134 Score = 30.0 bits (66), Expect = 6.7 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%) Query: 59 EKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVL-----IRLSHLLSE 113 E + + P E Q ++ A+ P LL L G + D D QAA + + L HLLSE Sbjct: 265 EHKPVAVPSAEAQGLRELEGASDP--LLSLFGSTSDNDLLQAATAMDSLTDLDLEHLLSE 322 Query: 114 KPE 116 PE Sbjct: 323 SPE 325 >gi|118572601 ubinuclein 1 [Homo sapiens] Length = 1134 Score = 30.0 bits (66), Expect = 6.7 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 7/63 (11%) Query: 59 EKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVL-----IRLSHLLSE 113 E + + P E Q ++ A+ P LL L G + D D QAA + + L HLLSE Sbjct: 265 EHKPVAVPSAEAQGLRELEGASDP--LLSLFGSTSDNDLLQAATAMDSLTDLDLEHLLSE 322 Query: 114 KPE 116 PE Sbjct: 323 SPE 325 >gi|13129124 caspase recruitment domain protein 14 isoform 1 [Homo sapiens] Length = 1004 Score = 30.0 bits (66), Expect = 6.7 Identities = 39/174 (22%), Positives = 69/174 (39%), Gaps = 21/174 (12%) Query: 40 TSSATSPISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQ 99 TS T ++ GSL E + +E+ + ++ L + E E G H L+++ Sbjct: 121 TSKLTECLAGAIGSLQEELNQEKGQKEVLLRRCQQLQEHLGLAETRAE---GLHQLEADH 177 Query: 100 AAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIP 159 + M K E AHFH++L L + ++ H + + L A Sbjct: 178 SRM-----------KRE------VSAHFHEVLRLKDEMLSLSLHYSNALQEKELAASRCR 220 Query: 160 KASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLER 213 +EL ++QE++ R + L +S T S ++ E L L E+ Sbjct: 221 SLQEELYLLKQELQ-RANMVSSCELELQEQSLRTASDQESGDEELNRLKEENEK 273 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.134 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,345,836 Number of Sequences: 37866 Number of extensions: 1087116 Number of successful extensions: 3264 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 8 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 3219 Number of HSP's gapped (non-prelim): 54 length of query: 631 length of database: 18,247,518 effective HSP length: 108 effective length of query: 523 effective length of database: 14,157,990 effective search space: 7404628770 effective search space used: 7404628770 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.