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Search of human proteins with 40068059
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40068059 CBF1 interacting corepressor [Homo sapiens]
(450 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 914 0.0
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 87 4e-17
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 87 4e-17
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 86 9e-17
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 86 9e-17
gi|8923271 coiled-coil domain containing 49 [Homo sapiens] 84 3e-16
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 82 1e-15
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 81 2e-15
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 80 3e-15
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 77 2e-14
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 77 2e-14
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 77 4e-14
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 75 9e-14
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 71 2e-12
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 71 2e-12
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 71 2e-12
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 71 2e-12
gi|52426743 cisplatin resistance-associated overexpressed protei... 71 2e-12
gi|19923485 cisplatin resistance-associated overexpressed protei... 71 2e-12
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 69 7e-12
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 69 7e-12
gi|50962882 G patch domain containing 8 [Homo sapiens] 69 9e-12
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 69 1e-11
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 69 1e-11
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 68 2e-11
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap... 67 3e-11
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 67 3e-11
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 67 3e-11
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 67 4e-11
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 66 7e-11
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 914 bits (2361), Expect = 0.0
Identities = 450/450 (100%), Positives = 450/450 (100%)
Query: 1 MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMG 60
MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMG
Sbjct: 1 MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMG 60
Query: 61 DERVKNGLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFG 120
DERVKNGLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFG
Sbjct: 61 DERVKNGLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFG 120
Query: 121 IQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFA 180
IQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFA
Sbjct: 121 IQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFA 180
Query: 181 LKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDR 240
LKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDR
Sbjct: 181 LKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDR 240
Query: 241 KKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCS 300
KKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCS
Sbjct: 241 KKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCS 300
Query: 301 GHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSR 360
GHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSR
Sbjct: 301 GHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSR 360
Query: 361 THKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRND 420
THKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRND
Sbjct: 361 THKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRND 420
Query: 421 SRSHGTDLYRGEKMYREHPGGTHTKVTQRE 450
SRSHGTDLYRGEKMYREHPGGTHTKVTQRE
Sbjct: 421 SRSHGTDLYRGEKMYREHPGGTHTKVTQRE 450
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 86.7 bits (213), Expect = 4e-17
Identities = 66/229 (28%), Positives = 113/229 (49%), Gaps = 14/229 (6%)
Query: 201 ASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSS 260
+SE ++D E+ F+K T +K K + D+ EK+KK+ + + ++S+S K + +S
Sbjct: 1783 SSEEKDDYEI-FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTS 1841
Query: 261 SSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEE-----KDKSKK 315
S S + S+++ S++ S ++ ++ +R R ++K G + E+ K +SK
Sbjct: 1842 ESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKS 1901
Query: 316 RKLHEELSSSHHNREKAKEKPRFLKHES-SREDSKWSHSDSDKKSRTHKHSPEKRGSERK 374
R+ + SSS NR+ + + R S S S+ S S + R+ SP +R S
Sbjct: 1902 RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRR-SRTP 1960
Query: 375 EGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRS 423
SR+ R R+ RSR+P ++ T R R P SRR SRS
Sbjct: 1961 SRRSRTPSRRSRTPSRRSRTPS--RRSRTPSRRSRTP----SRRRRSRS 2003
Score = 57.0 bits (136), Expect = 3e-08
Identities = 54/189 (28%), Positives = 74/189 (39%), Gaps = 33/189 (17%)
Query: 260 SSSSSSSSSSSTETSESSSESESNNK---EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKR 316
S++S SS SESSSE + + + + K +K KKNK +DK +K
Sbjct: 1766 SAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNK----------NRDKGEKE 1815
Query: 317 KLHEELSSSHHNREKAKE-KPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKE 375
K + S R K+ E K R ES K S +S+T S +R
Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR 1875
Query: 376 GSSRSHGREERSRRSRSRSPGSYKQRETRKR-------------------AQRNPGEEQS 416
S+S GR S+ R RSP + RKR ++R+ S
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935
Query: 417 RRNDSRSHG 425
RR SRS G
Sbjct: 1936 RRRRSRSVG 1944
Score = 54.7 bits (130), Expect = 2e-07
Identities = 57/217 (26%), Positives = 88/217 (40%), Gaps = 13/217 (5%)
Query: 214 KSLTTKQKQKLLRKLDRLEKKKKK-KDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTE 272
KS K +++ R K+ K K + + +SRS+ ++ S S S S S S E
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889
Query: 273 TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKA 332
+ S + S ++E+K +R + N+ + S + + S S R
Sbjct: 1890 KRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSF 1949
Query: 333 KEKPRFLKHESSREDSKWSHSDSDKKSRT---HKHSPEKRGSERKEGSSRSHGREERSR- 388
P SR S+ S + S ++SRT +P +R S SR+ R RSR
Sbjct: 1950 SISP----SRRSRTPSRRSRTPS-RRSRTPSRRSRTPSRR-SRTPSRRSRTPSRRRRSRS 2003
Query: 389 --RSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRS 423
R RS S + R +R +R RR SRS
Sbjct: 2004 VVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRS 2040
Score = 32.7 bits (73), Expect = 0.69
Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 10/93 (10%)
Query: 251 KHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEK 310
++K S S S + T E ++ +K+ K ++KK+KK K + E +
Sbjct: 78 RYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESE 137
Query: 311 DKSKKRKLHEELSSSHHNREKAKEKPRFLKHES 343
K+K SH + E FLK +S
Sbjct: 138 SKTK----------SHDDGNIDLESDSFLKFDS 160
Score = 32.3 bits (72), Expect = 0.90
Identities = 17/52 (32%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 216 LTTKQKQKLLRKLDRLEKKKKKKDRK-KKKFQKSRSKHKKHKSSSSSSSSSS 266
+ TK+ +K + ++ +KKKK+K++K K++ ++S SK K H + S S
Sbjct: 103 IPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
Score = 32.0 bits (71), Expect = 1.2
Identities = 14/46 (30%), Positives = 24/46 (52%)
Query: 232 EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESS 277
+K KK K++KKKK ++ K+K+ S S + S + + S
Sbjct: 109 KKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 86.7 bits (213), Expect = 4e-17
Identities = 66/229 (28%), Positives = 113/229 (49%), Gaps = 14/229 (6%)
Query: 201 ASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSS 260
+SE ++D E+ F+K T +K K + D+ EK+KK+ + + ++S+S K + +S
Sbjct: 1783 SSEEKDDYEI-FVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTS 1841
Query: 261 SSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEE-----KDKSKK 315
S S + S+++ S++ S ++ ++ +R R ++K G + E+ K +SK
Sbjct: 1842 ESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKS 1901
Query: 316 RKLHEELSSSHHNREKAKEKPRFLKHES-SREDSKWSHSDSDKKSRTHKHSPEKRGSERK 374
R+ + SSS NR+ + + R S S S+ S S + R+ SP +R S
Sbjct: 1902 RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRR-SRTP 1960
Query: 375 EGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRS 423
SR+ R R+ RSR+P ++ T R R P SRR SRS
Sbjct: 1961 SRRSRTPSRRSRTPSRRSRTPS--RRSRTPSRRSRTP----SRRRRSRS 2003
Score = 57.0 bits (136), Expect = 3e-08
Identities = 54/189 (28%), Positives = 74/189 (39%), Gaps = 33/189 (17%)
Query: 260 SSSSSSSSSSSTETSESSSESESNNK---EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKR 316
S++S SS SESSSE + + + + K +K KKNK +DK +K
Sbjct: 1766 SAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNK----------NRDKGEKE 1815
Query: 317 KLHEELSSSHHNREKAKE-KPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKE 375
K + S R K+ E K R ES K S +S+T S +R
Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR 1875
Query: 376 GSSRSHGREERSRRSRSRSPGSYKQRETRKR-------------------AQRNPGEEQS 416
S+S GR S+ R RSP + RKR ++R+ S
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935
Query: 417 RRNDSRSHG 425
RR SRS G
Sbjct: 1936 RRRRSRSVG 1944
Score = 54.7 bits (130), Expect = 2e-07
Identities = 57/217 (26%), Positives = 88/217 (40%), Gaps = 13/217 (5%)
Query: 214 KSLTTKQKQKLLRKLDRLEKKKKK-KDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTE 272
KS K +++ R K+ K K + + +SRS+ ++ S S S S S S E
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889
Query: 273 TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKA 332
+ S + S ++E+K +R + N+ + S + + S S R
Sbjct: 1890 KRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSF 1949
Query: 333 KEKPRFLKHESSREDSKWSHSDSDKKSRT---HKHSPEKRGSERKEGSSRSHGREERSR- 388
P SR S+ S + S ++SRT +P +R S SR+ R RSR
Sbjct: 1950 SISP----SRRSRTPSRRSRTPS-RRSRTPSRRSRTPSRR-SRTPSRRSRTPSRRRRSRS 2003
Query: 389 --RSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRS 423
R RS S + R +R +R RR SRS
Sbjct: 2004 VVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRS 2040
Score = 32.7 bits (73), Expect = 0.69
Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 10/93 (10%)
Query: 251 KHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEK 310
++K S S S + T E ++ +K+ K ++KK+KK K + E +
Sbjct: 78 RYKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESE 137
Query: 311 DKSKKRKLHEELSSSHHNREKAKEKPRFLKHES 343
K+K SH + E FLK +S
Sbjct: 138 SKTK----------SHDDGNIDLESDSFLKFDS 160
Score = 32.3 bits (72), Expect = 0.90
Identities = 17/52 (32%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 216 LTTKQKQKLLRKLDRLEKKKKKKDRK-KKKFQKSRSKHKKHKSSSSSSSSSS 266
+ TK+ +K + ++ +KKKK+K++K K++ ++S SK K H + S S
Sbjct: 103 IPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
Score = 32.0 bits (71), Expect = 1.2
Identities = 14/46 (30%), Positives = 24/46 (52%)
Query: 232 EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESS 277
+K KK K++KKKK ++ K+K+ S S + S + + S
Sbjct: 109 KKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDS 154
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 85.5 bits (210), Expect = 9e-17
Identities = 65/232 (28%), Positives = 98/232 (42%), Gaps = 22/232 (9%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKF-QKSRSKHKKHKSSSSSSSSSSSSSSTE----- 272
K+ Q R + ++KDR++ K K RSK ++ + S S S S T
Sbjct: 327 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 386
Query: 273 ---TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNR 329
E E E ++++ + K+R KNK EKDK K R+ E H +
Sbjct: 387 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE---KEHEK 443
Query: 330 EKAKEKPRFLKHESSREDSKWSHSDS----DKKSRTHKHSPEKRGSERKEGSSRSHGREE 385
++ KEK + E RE + D DKKSRT P + R+ SRS RE
Sbjct: 444 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT---PPRSYNASRR---SRSSSRER 497
Query: 386 RSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
R RRSRS S + ++++ R+P + D + + E+ RE
Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 549
Score = 70.1 bits (170), Expect = 4e-12
Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 12/185 (6%)
Query: 242 KKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKK---RKKNK 298
++K +SRS H + KS SSS S S S S S + S +++K +R K +K++K
Sbjct: 302 ERKGGRSRS-HTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360
Query: 299 CSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKK 358
S S + K++ E++ +EK +EK R + E +E + + D DK+
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420
Query: 359 SRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRR 418
+ +++ ER+ RE+ + R + + +E + R+ ++ R+
Sbjct: 421 REKDREKDKEKDRERE--------REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 472
Query: 419 NDSRS 423
D +S
Sbjct: 473 KDKKS 477
Score = 64.7 bits (156), Expect = 2e-10
Identities = 41/198 (20%), Positives = 82/198 (41%), Gaps = 4/198 (2%)
Query: 214 KSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTET 273
K T++K K ++ +++K+++ K+++ +K R K+K E
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 435
Query: 274 SESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAK 333
+ +KEK+ ++ K K+ + D + K K R ++S +R ++
Sbjct: 436 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 495
Query: 334 EKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRG-SERKEGSSRSHGREERSRRSRS 392
E+ R SSR S + K+ + SP R ++K R H E R R +
Sbjct: 496 ERRRRRSRSSSRSPRT---SKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERST 552
Query: 393 RSPGSYKQRETRKRAQRN 410
S R+ +++ ++N
Sbjct: 553 SMRKSSNDRDGKEKLEKN 570
Score = 60.8 bits (146), Expect = 2e-09
Identities = 45/223 (20%), Positives = 94/223 (42%), Gaps = 9/223 (4%)
Query: 205 EEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKK---KKFQKSRSKHKKHKSSSSS 261
E+ E E +K +++++ ++ ++ +++ K KDR K K +K + K ++ +
Sbjct: 382 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH 441
Query: 262 SSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHN-NSDSEEKDKSKKRKLHE 320
E + + +KE +RKK KK++ + N+ + S++R+
Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 501
Query: 321 ELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRS 380
SSS R + +K +SSR S S + DKK + +R + S R
Sbjct: 502 SRSSSRSPRTS-----KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 556
Query: 381 HGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRS 423
+ + ++ S K++E K + +E ++ R+
Sbjct: 557 SSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRT 599
Score = 54.7 bits (130), Expect = 2e-07
Identities = 45/179 (25%), Positives = 87/179 (48%), Gaps = 15/179 (8%)
Query: 205 EEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSS 264
E + E E K +++++ ++ +R + + K+ D K+KK +KSR+ + + +S S SS
Sbjct: 434 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 493
Query: 265 S---------SSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKK 315
S SSS S TS++ S + + + KK KK + + S+ E+++S
Sbjct: 494 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTS 553
Query: 316 RKLHEELSSSHHNREKAKEKPRFLKHE--SSREDSKWSHSDSDKKS-RTHKHSPEKRGS 371
+ + S+ +EK ++ LK + + DS S DK + RT ++ + G+
Sbjct: 554 MR---KSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGN 609
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 85.5 bits (210), Expect = 9e-17
Identities = 65/232 (28%), Positives = 98/232 (42%), Gaps = 22/232 (9%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKF-QKSRSKHKKHKSSSSSSSSSSSSSSTE----- 272
K+ Q R + ++KDR++ K K RSK ++ + S S S S T
Sbjct: 211 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 270
Query: 273 ---TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNR 329
E E E ++++ + K+R KNK EKDK K R+ E H +
Sbjct: 271 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE---KEHEK 327
Query: 330 EKAKEKPRFLKHESSREDSKWSHSDS----DKKSRTHKHSPEKRGSERKEGSSRSHGREE 385
++ KEK + E RE + D DKKSRT P + R+ SRS RE
Sbjct: 328 DRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT---PPRSYNASRR---SRSSSRER 381
Query: 386 RSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
R RRSRS S + ++++ R+P + D + + E+ RE
Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 433
Score = 70.1 bits (170), Expect = 4e-12
Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 12/185 (6%)
Query: 242 KKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKK---RKKNK 298
++K +SRS H + KS SSS S S S S S + S +++K +R K +K++K
Sbjct: 186 ERKGGRSRS-HTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244
Query: 299 CSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKK 358
S S + K++ E++ +EK +EK R + E +E + + D DK+
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304
Query: 359 SRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRR 418
+ +++ ER+ RE+ + R + + +E + R+ ++ R+
Sbjct: 305 REKDREKDKEKDRERE--------REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 356
Query: 419 NDSRS 423
D +S
Sbjct: 357 KDKKS 361
Score = 64.7 bits (156), Expect = 2e-10
Identities = 41/198 (20%), Positives = 82/198 (41%), Gaps = 4/198 (2%)
Query: 214 KSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTET 273
K T++K K ++ +++K+++ K+++ +K R K+K E
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 319
Query: 274 SESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAK 333
+ +KEK+ ++ K K+ + D + K K R ++S +R ++
Sbjct: 320 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 379
Query: 334 EKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRG-SERKEGSSRSHGREERSRRSRS 392
E+ R SSR S + K+ + SP R ++K R H E R R +
Sbjct: 380 ERRRRRSRSSSRSPRT---SKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERST 436
Query: 393 RSPGSYKQRETRKRAQRN 410
S R+ +++ ++N
Sbjct: 437 SMRKSSNDRDGKEKLEKN 454
Score = 60.8 bits (146), Expect = 2e-09
Identities = 45/223 (20%), Positives = 94/223 (42%), Gaps = 9/223 (4%)
Query: 205 EEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKK---KKFQKSRSKHKKHKSSSSS 261
E+ E E +K +++++ ++ ++ +++ K KDR K K +K + K ++ +
Sbjct: 266 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH 325
Query: 262 SSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHN-NSDSEEKDKSKKRKLHE 320
E + + +KE +RKK KK++ + N+ + S++R+
Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 385
Query: 321 ELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRS 380
SSS R + +K +SSR S S + DKK + +R + S R
Sbjct: 386 SRSSSRSPRTS-----KTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 440
Query: 381 HGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRS 423
+ + ++ S K++E K + +E ++ R+
Sbjct: 441 SSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRT 483
Score = 54.7 bits (130), Expect = 2e-07
Identities = 45/179 (25%), Positives = 87/179 (48%), Gaps = 15/179 (8%)
Query: 205 EEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSS 264
E + E E K +++++ ++ +R + + K+ D K+KK +KSR+ + + +S S SS
Sbjct: 318 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 377
Query: 265 S---------SSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKK 315
S SSS S TS++ S + + + KK KK + + S+ E+++S
Sbjct: 378 SRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTS 437
Query: 316 RKLHEELSSSHHNREKAKEKPRFLKHE--SSREDSKWSHSDSDKKS-RTHKHSPEKRGS 371
+ + S+ +EK ++ LK + + DS S DK + RT ++ + G+
Sbjct: 438 MR---KSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGN 493
>gi|8923271 coiled-coil domain containing 49 [Homo sapiens]
Length = 425
Score = 84.0 bits (206), Expect = 3e-16
Identities = 102/441 (23%), Positives = 179/441 (40%), Gaps = 90/441 (20%)
Query: 11 KKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGD----ERVKN 66
KK +HP + N++KVW AEQK ++KK EEL ++ +E+ + + D ++ +
Sbjct: 9 KKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEE 68
Query: 67 GLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNV 126
L++MY+ P G + E+ G P +KY + M
Sbjct: 69 KLDWMYQGPGGMVNRD--------------EYLLGRPIDKYVFEKME------------- 101
Query: 127 RCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVL 186
++E +G+ S+ S+ ++ +++R
Sbjct: 102 -------------EKEAGCSSETGLLPGSIFAPSGANSL--LDMASKIRE---------- 136
Query: 187 GRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQ 246
DP ++ + EE+ + E L + +K K L ++ LEKK+KKK ++KKK
Sbjct: 137 -------DPL--FIIRKKEEEKKREVLNNPVKMKKIKELLQMS-LEKKEKKKKKEKKK-- 184
Query: 247 KSRSKHKKHK--SSSSSSSSSSSSSSTETSESSSESESN--NKEKKIQRKKRKKNKCSGH 302
KHKKHK SSSS SSS S S+ + S +K + R ++ G
Sbjct: 185 ----KHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGL 240
Query: 303 NNSDSEEKDKSKKRKLHEELSSSHHN--REKAKEKPRFLKHESSREDSKWSHSDSDKKSR 360
+ E+ + K H SS H+ R +K+ R R S S S + S+
Sbjct: 241 QGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSK 300
Query: 361 THKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYK-------QRETRKRAQRNPGE 413
H + + R+ G +RS ++ R +PG + +R+ ++ +
Sbjct: 301 LH----NSKVNRRETGQTRSPS-PKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWR 355
Query: 414 EQSRRNDSRSHGTDLYRGEKM 434
E+ R N + H D R +++
Sbjct: 356 EEERLNILKRHAKDEEREQRL 376
Score = 48.1 bits (113), Expect = 2e-05
Identities = 52/230 (22%), Positives = 85/230 (36%), Gaps = 22/230 (9%)
Query: 242 KKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSG 301
K F+K K S + S + S S S+ I RKK ++ K
Sbjct: 94 KYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREV 153
Query: 302 HNNS------------DSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSK 349
NN E+K+K KK++ ++ H + +H + R K
Sbjct: 154 LNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKK 213
Query: 350 WSHSDSDKKSRTHKHSPEKRGSERKEG--------SSRSHGREERSR-RSRSRSPGSYKQ 400
++S S S+ + + R S+R +G R HG + SR RS S SP +
Sbjct: 214 MANS-SPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHAS 272
Query: 401 RETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE 450
+++ + A +S SRS K+ R G T + ++E
Sbjct: 273 KKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKE 322
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 81.6 bits (200), Expect = 1e-15
Identities = 50/216 (23%), Positives = 105/216 (48%), Gaps = 20/216 (9%)
Query: 226 RKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNK 285
R+++ ++ KK+++ ++KK ++ R K K+ + + E + K
Sbjct: 43 REIETRKEGKKERESERKKERREREKRKREREKER-----------KRERGKKEKKGERK 91
Query: 286 EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR 345
+++ +RKKR++ K N + EEK+K KK++ E +S +E+ +++ R + R
Sbjct: 92 KEERERKKRRREK----ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
Query: 346 EDSKWSHSD----SDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQR 401
E K ++K R K EK ERKE + + ER+R+ R + ++R
Sbjct: 148 ERKKEEREKERERKERKKRERKQVGEKE-EERKEKERKERKKRERNRKERKKERERKERR 206
Query: 402 ETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
E +K ++ ++ R+ D +++ + RG++ +E
Sbjct: 207 ERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 80.1 bits (196), Expect = 4e-15
Identities = 51/214 (23%), Positives = 94/214 (43%), Gaps = 10/214 (4%)
Query: 205 EEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSS 264
E + E+E K K++++ RK +R E++K+K++R+K ++ R + KK K
Sbjct: 40 EREREIETRKE--GKKERESERKKERREREKRKREREK---ERKRERGKKEKKGERKKEE 94
Query: 265 SSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSS 324
E+ E E K KK ++K+R + G EE+ + ++++ +
Sbjct: 95 RERKKRRREKENK-EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Query: 325 SHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGRE 384
RE+ + K R K +E+ + ++K R K+ ERKE R R+
Sbjct: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
Query: 385 ERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRR 418
++ R + R K R+T R + E+ R
Sbjct: 214 KKEERKKERQ----KDRQTNWREKERGKRERKER 243
Score = 72.0 bits (175), Expect = 1e-12
Identities = 46/205 (22%), Positives = 94/205 (45%), Gaps = 11/205 (5%)
Query: 203 EGEEDPEVEFLKSLTTKQKQKLLRKLDRL-EKKKKKKDRKKKKFQKSRSKHKKHKSSSSS 261
EG+++ E E K ++K+K R+ +R E+ KK+K ++KK ++ R K ++ K +
Sbjct: 50 EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEG 109
Query: 262 SSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEE 321
+ + E +E+K +RK+ ++ + +E+++ +++K +
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERK 169
Query: 322 LSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSH 381
K KE+ K E +R++ K K R K E++ ERK+ R
Sbjct: 170 QVGEKEEERKEKERKERKKRERNRKERK--------KERERKERRERK-KERKKKEERKK 220
Query: 382 GRE-ERSRRSRSRSPGSYKQRETRK 405
R+ +R R + G +++E +K
Sbjct: 221 ERQKDRQTNWREKERGKRERKERKK 245
Score = 61.2 bits (147), Expect = 2e-09
Identities = 46/204 (22%), Positives = 83/204 (40%), Gaps = 3/204 (1%)
Query: 247 KSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSD 306
K+ S K ++ S S S ++ +SE +E++I+ +K K + +
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKE 62
Query: 307 SEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSP 366
E++K +KR+ +E +EK E+ + + R K + +K+ R K
Sbjct: 63 RREREK-RKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121
Query: 367 EKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGT 426
E RG KEG R +EER R R ++RE + + E+ + +
Sbjct: 122 E-RGRTSKEGKERER-KEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK 179
Query: 427 DLYRGEKMYREHPGGTHTKVTQRE 450
+ R E+ RE K +R+
Sbjct: 180 EKERKERKKRERNRKERKKERERK 203
Score = 56.2 bits (134), Expect = 6e-08
Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 11/188 (5%)
Query: 188 RNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQK 247
R + +E G+++ + E K ++K++ ++ E+K+K+K ++KK
Sbjct: 66 REKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK---- 121
Query: 248 SRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDS 307
++ ++S E + +EK+ +RK+RKK + +
Sbjct: 122 -----ERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEE 176
Query: 308 EEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPE 367
E K+K +K + E + +E+ +++ R K E +++ + D+++ +
Sbjct: 177 ERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
Query: 368 KRGSERKE 375
KR ERKE
Sbjct: 237 KR--ERKE 242
Score = 37.4 bits (85), Expect = 0.028
Identities = 25/122 (20%), Positives = 52/122 (42%), Gaps = 11/122 (9%)
Query: 201 ASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSS 260
+ EG+E E K K+++ RK + EK++++K+RKK++ ++ K ++ K
Sbjct: 127 SKEGKERERKEERKREERKERE---RKKEEREKERERKERKKRERKQVGEKEEERKEKER 183
Query: 261 SSSSSSSSSSTETSESSSESESNNK--------EKKIQRKKRKKNKCSGHNNSDSEEKDK 312
+ E + E + E+K +R+K ++ E K++
Sbjct: 184 KERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
Query: 313 SK 314
K
Sbjct: 244 KK 245
Score = 32.7 bits (73), Expect = 0.69
Identities = 21/99 (21%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
Query: 197 QEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKK---DRKKKKFQKSRSKHK 253
+E E E++ E + K KQ + + E+K++KK +RK++K ++ R + +
Sbjct: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR 206
Query: 254 KHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRK 292
+ K + + E E +E+K ++K
Sbjct: 207 ERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 80.9 bits (198), Expect = 2e-15
Identities = 73/266 (27%), Positives = 117/266 (43%), Gaps = 31/266 (11%)
Query: 188 RNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQK 247
R +T + E + E++ +V+ KS K++ +R+ + K K K +K+ K K
Sbjct: 404 RKITDHRNVSESPNRKNEKEKKVKDHKS---NSKERDIRRNSEKDDKYKNKVKKRAK-SK 459
Query: 248 SRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDS 307
SRSK K+ S S S E S S ++ + ++K K++ G + S
Sbjct: 460 SRSKSKE-----KSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERS 514
Query: 308 EEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSRED-SKWSHS-DSDKKSRTHKHS 365
K+KSK+ E S+ H+ K+KEK R + S D +K HS +S + R+
Sbjct: 515 RSKEKSKQL----ESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD 570
Query: 366 PEKRGSERKEGSSRSHGRE-------ERSRRSRSRS------PGSYKQRETRKRAQRNPG 412
+R R RS +E E RR RSRS PG + ++ R+R +
Sbjct: 571 RSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRR---D 627
Query: 413 EEQSRRNDSRSHGTDLYRGEKMYREH 438
S R +S+S D YR ++ H
Sbjct: 628 SRSSEREESQSRNKDKYRNQESKSSH 653
Score = 76.6 bits (187), Expect = 4e-14
Identities = 60/223 (26%), Positives = 104/223 (46%), Gaps = 23/223 (10%)
Query: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKK 288
+R K K + + K+ Q+S + K+ K + + S S + E + + +SN+KE+
Sbjct: 378 ERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERD 437
Query: 289 IQRKKRK----KNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESS 344
I+R K KNK S S K K K + + + + ++ + + + HE+
Sbjct: 438 IRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENV 497
Query: 345 REDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGR---EERSRRSRSRS------- 394
+E K SD K + + S K S++ E S H +E+ RR++SRS
Sbjct: 498 KEKEK----QSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITK 553
Query: 395 -PGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYR 436
SY R TR+R++ ++SRR SR+H D R ++ +R
Sbjct: 554 GKHSYNSR-TRERSR---SRDRSRRVRSRTHDRDRSRSKEYHR 592
Score = 73.2 bits (178), Expect = 5e-13
Identities = 63/287 (21%), Positives = 125/287 (43%), Gaps = 23/287 (8%)
Query: 162 GPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQK 221
G +E+ R+ +R + + P+++ + +D + + +
Sbjct: 383 GDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNS 442
Query: 222 QKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSS----SSSSSSSSTETSESS 277
+K + ++++K+ K K R K K +KS+SK + K + + S S E
Sbjct: 443 EKDDKYKNKVKKRAKSKSRSKSK-EKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKE 501
Query: 278 SESESNNKEKKIQRKKRK----KNKCSGHNNSDSEEKDKSKKRKLHE-ELSSSHHN---- 328
+S+S K+++ R K K ++K + H++S S+EKD+ + + E +++ H+
Sbjct: 502 KQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSR 561
Query: 329 -REKAKEKPRFLK-----HESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHG 382
RE+++ + R + H+ R SK H +++ R S R ER+ RS
Sbjct: 562 TRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRS---RSRERRTPPGRSRS 618
Query: 383 REERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLY 429
++ R RR SRS + + K RN + S R ++ +Y
Sbjct: 619 KDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMY 665
Score = 72.8 bits (177), Expect = 6e-13
Identities = 62/224 (27%), Positives = 106/224 (47%), Gaps = 37/224 (16%)
Query: 231 LEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQ 290
+ K K KK+ KK+ HK SSSSSSS S SSS +++S SS+SES +EK +
Sbjct: 178 IPKSKVKKEEKKR--------HKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKK 229
Query: 291 RKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKP-------------- 336
RKK+ H + + K + KKRK ++ +SS E + +P
Sbjct: 230 RKKK-------HRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPE 282
Query: 337 -RFLKHES--SREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRS- 392
RFL +S ++ + + + +++ + + + +R+ +RS GR+ + R R
Sbjct: 283 NRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRS-GRKIKGRGPRRY 341
Query: 393 RSPGSYKQRETRKRAQRNPGEEQSRRNDSR---SHGTDLYRGEK 433
R+P + R+ +R++ P Q + R S G +G+K
Sbjct: 342 RTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDK 385
Score = 67.0 bits (162), Expect = 3e-11
Identities = 48/209 (22%), Positives = 96/209 (45%), Gaps = 21/209 (10%)
Query: 226 RKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNK 285
R + +++K+K+ D K K ++SRSK K + S S+ S+S K
Sbjct: 492 RDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSN-------------EHDHSKSKEK 538
Query: 286 EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR 345
+++ Q + R+ + G ++ +S +++S+ R + S H+R++++ K H
Sbjct: 539 DRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKE---YHRYRE 595
Query: 346 EDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRK 405
++ + ++ RT + R+ SRS REE S+SR+ Y+ +E++
Sbjct: 596 QEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREE----SQSRNKDKYRNQESKS 651
Query: 406 RAQRNPGEEQSRR-NDSRSHGTDLYRGEK 433
++ E + R + SR H + EK
Sbjct: 652 SHRKENSESEKRMYSKSRDHNSSNNSREK 680
Score = 63.2 bits (152), Expect = 5e-10
Identities = 57/221 (25%), Positives = 97/221 (43%), Gaps = 19/221 (8%)
Query: 233 KKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNN-KEKKIQR 291
++ + R + + + RS+ H + SS E +SE N KE +
Sbjct: 339 RRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSP 398
Query: 292 KKRKKNKCSGHNN---SDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDS 348
+ K+ K + H N S + + +K KK K H+ S R +++ ++ R S
Sbjct: 399 VRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKS 458
Query: 349 KWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGRE-----ERSRRS--------RSRSP 395
K S S S +KS++ + + +E K SRS GR+ E+ ++S RSRS
Sbjct: 459 K-SRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSK 517
Query: 396 GSYKQRETRKRA-QRNPGEEQSRRNDSRSHGTDLYRGEKMY 435
KQ E++ + +E+ RR SRS D+ +G+ Y
Sbjct: 518 EKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSY 558
Score = 51.2 bits (121), Expect = 2e-06
Identities = 62/302 (20%), Positives = 116/302 (38%), Gaps = 48/302 (15%)
Query: 193 NDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKH 252
+D S + +S D E + +K+++K RK R KK+KKK +K KK S S+
Sbjct: 204 SDSSSDSQSSSDSSDSESATEEK--SKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEA 261
Query: 253 KKHKSSSSSSSSSSSSSSTETSE---SSSESESNNKEKKIQRKKRKKNKCSGHNN----- 304
+ ++ S+ + S +++ KE+K R++ ++ +C+ N+
Sbjct: 262 ENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERK-NRERERERECNPPNSQPASY 320
Query: 305 ------SDSEEKDKSK-KRKLHEELSSSHHNREKAKEKPRFLKHESSR-------EDSKW 350
+ S K K + R+ S +R + E P + E R +W
Sbjct: 321 QRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERW 380
Query: 351 SHSD-----------------SDKKSRTHKH---SPEKRGSERKEGSSRSHGREERSRRS 390
D ++K H++ SP ++ + K+ +ER R
Sbjct: 381 IKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRR 440
Query: 391 RSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGE--KMYREHPGGTHTKVTQ 448
S YK + +KRA+ + ++ S+ + R E +M G H V +
Sbjct: 441 NSEKDDKYKNK-VKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKE 499
Query: 449 RE 450
+E
Sbjct: 500 KE 501
Score = 49.7 bits (117), Expect = 5e-06
Identities = 46/236 (19%), Positives = 99/236 (41%), Gaps = 18/236 (7%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKK---------KFQKSRSKHKKHKSSSSSSSSSSSSS 269
K KQ + + K K+KDR+ + K + S + + +S S S S
Sbjct: 519 KSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSR 578
Query: 270 STETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNR 329
+ + S S+ +E++ +R+ R +++ S KD+ ++R+ + SS
Sbjct: 579 THDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRR---DSRSSEREE 635
Query: 330 EKAKEKPRFLKHESSREDSKWSHSDSDKK--SRTHKHSPEKRGSERKEGSSRS-HGREER 386
+++ K ++ +++ S+ + +S+S+K+ S++ H+ E+K +S + ++
Sbjct: 636 SQSRNKDKY-RNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQ 694
Query: 387 SRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGT 442
S + K +E K E Q + H + + +K E GT
Sbjct: 695 SSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHE--KNKKFDHESSPGT 748
Score = 35.8 bits (81), Expect = 0.081
Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 11/124 (8%)
Query: 201 ASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDR--------KKKKFQKSRSKH 252
+SE EE K + K ++ EK+ K R ++KK + +S
Sbjct: 630 SSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPF 689
Query: 253 KKHKSSSSSSSSSSSSSSTETSE---SSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEE 309
K K SS + SS + E SS E E+ + + +KNK H +S +
Sbjct: 690 SKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTD 749
Query: 310 KDKS 313
+DKS
Sbjct: 750 EDKS 753
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 80.5 bits (197), Expect = 3e-15
Identities = 65/218 (29%), Positives = 100/218 (45%), Gaps = 19/218 (8%)
Query: 226 RKLDRLEKKKKKKDRKK------KKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSE 279
RK+ +E K + R+ +SRS+H + S S SS SS S S S S S
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 280 SESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFL 339
S S ++ + R + KK K S S K+KS+ R H S ++++A+EK
Sbjct: 228 SRSKSRSRSQSRSRSKKEK------SRSPSKEKSRSRS-HSAGKSRSKSKDQAEEK--IQ 278
Query: 340 KHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGS---SRSHGREERSRRSRSRSPG 396
+++ + S S KS++ S E+R E K GS RS + R RSRSRS G
Sbjct: 279 NNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKG 338
Query: 397 SYKQRETRKRAQRNPGEEQSR-RNDSRSHGTDLYRGEK 433
+ R + ++ + + R R +SRS + E+
Sbjct: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER 376
Score = 80.5 bits (197), Expect = 3e-15
Identities = 72/238 (30%), Positives = 104/238 (43%), Gaps = 19/238 (7%)
Query: 213 LKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTE 272
++ + K + R R + + R + +KSRS+ KSS S S S S S S
Sbjct: 170 IRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHS-RKSRSRSGSSKSSHSKSRSRSRSGSRS 228
Query: 273 TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKA 332
S+S S S+S ++ KK K R +K + S S K +SK + EE ++ N K
Sbjct: 229 RSKSRSRSQSRSRSKK--EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP 286
Query: 333 KEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRR--- 389
K + SR SK S S +S+ + EKRGS + S R+ RSR
Sbjct: 287 KSR------SPSRHKSK---SKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSK 337
Query: 390 --SRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTK 445
SRSRS K ++ RK +R+ E +SR RG K R+ G+ K
Sbjct: 338 GGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSK--RDSKAGSSKK 393
Score = 78.2 bits (191), Expect = 1e-14
Identities = 60/223 (26%), Positives = 98/223 (43%), Gaps = 9/223 (4%)
Query: 203 EGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSS 262
E P E +S + + + D+ E+K + D K +S S+HK S S
Sbjct: 245 EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSK----SKS 300
Query: 263 SSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSK-KRKLHEE 321
S S E + S S ++EK + R+ R +++ G + S S + KSK KRK +
Sbjct: 301 RSRSQERRVEEEKRGSVSRGRSQEKSL-RQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR 359
Query: 322 LSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSH 381
+R +++ K + S+ DSK S KK T + + R R R H
Sbjct: 360 SREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR--SQSRSPSRSVSKEREH 417
Query: 382 GREERSRR-SRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRS 423
+ E S+R R S + +ETR R++ N + + ++SRS
Sbjct: 418 AKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRS 460
Score = 72.8 bits (177), Expect = 6e-13
Identities = 64/224 (28%), Positives = 100/224 (44%), Gaps = 34/224 (15%)
Query: 230 RLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKI 289
R + + + + R + K +KSRS K+ S S S+ S S S + +E ++ N + K
Sbjct: 229 RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS 288
Query: 290 QRKKRKKNKCSGHNNSDS----EEKDKSKKRKLHEELS-------------SSHHNREKA 332
+ R K+K + S EEK S R +E S S +R ++
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348
Query: 333 KEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSER--KEGSSRSHGREERSR-- 388
K K + + SRE+S+ S +SR+ KRGS+R K GSS+ +E+ R
Sbjct: 349 KSKDKRKGRKRSREESR-----SRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
Query: 389 -RSRSRSPGSYKQRETRKRAQR-------NPGEEQSRRNDSRSH 424
RS SRS ++ + +QR N G Q R+ SRS+
Sbjct: 404 SRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSN 447
Score = 60.5 bits (145), Expect = 3e-09
Identities = 46/196 (23%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 218 TKQKQKLLRKLDRLEKKKK----KKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTET 273
+K K + + R+E++K+ + ++K ++SRS+ + S S S S S S
Sbjct: 296 SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRK 355
Query: 274 SESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAK 333
S ES ++ + R K ++++ G K KK++ + S +R +K
Sbjct: 356 GRKRSREESRSRSRS--RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
Query: 334 EKPRFLKHESSRE---DSKWSHSDSDKKSRTHKHSPEK-----RGSERKEGSSRSHGREE 385
E+ S RE +S+ + ++ + +SR+ +S K R + +S++ R +
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSK 473
Query: 386 RSRRSRSRSPGSYKQR 401
RS SRSP + R
Sbjct: 474 SRSRSASRSPSRSRSR 489
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 77.4 bits (189), Expect = 2e-14
Identities = 55/222 (24%), Positives = 97/222 (43%), Gaps = 22/222 (9%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSS 278
K++Q+L R+ EK++++ + ++ RS+ ++ S S S E
Sbjct: 299 KERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK 358
Query: 279 ESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRF 338
E+E + + K+R N +E+++S++R E+ S +K KE
Sbjct: 359 ENERGRRRDRDYDKER--------GNEREKERERSRERS-KEQRSRGEVEEKKHKEDKDD 409
Query: 339 LKHESSREDSKWSHSDSDKKSRTHKHSPEKRG----------SERKEGSSRSHGREERSR 388
+H + DSK S +SR KH R S+ K ++ +E+ ++
Sbjct: 410 RRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNK 469
Query: 389 RSRSRSPGSYKQRETRKRAQRNPGEEQSR---RNDSRSHGTD 427
RSRS S G E K+ + +P +E+SR R+ RSH D
Sbjct: 470 RSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRD 511
Score = 72.4 bits (176), Expect = 8e-13
Identities = 58/257 (22%), Positives = 107/257 (41%), Gaps = 29/257 (11%)
Query: 188 RNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQK 247
R L Q E + E +S+ +++ R +R + + +DRK + +
Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDR 352
Query: 248 SRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKK----IQRKKRKKNKCSGHN 303
R + K+++ E + S +KE++ ++ KK K++K +
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRH 412
Query: 304 NSDSEEKDKSKK-------RKLHEELSSSHH----NREKAKEKPRFLKHESSREDSKWSH 352
D + K KK + H S S + +R ++KEK K+ES + +K S
Sbjct: 413 RDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSR 472
Query: 353 S------DSDKKSRTHKHSPEKRGS-ERKEGSSRSHGREERSRRSRSRSPGSYKQRETRK 405
S DS +KS+ +HSP K S +R RSH R+ + +S + R+
Sbjct: 473 SGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQS-------DKHDRR 525
Query: 406 RAQRNPGEEQSRRNDSR 422
R+Q E Q +++ ++
Sbjct: 526 RSQSIEQESQEKQHKNK 542
Score = 69.3 bits (168), Expect = 7e-12
Identities = 57/249 (22%), Positives = 111/249 (44%), Gaps = 32/249 (12%)
Query: 207 DPEVEFLKSLTTKQKQKLLRKLDR-LEKKKKKKDRKKKKFQKS--RSKHKKHKSSSSSSS 263
D +++ K ++ ++DR +E+++ + R+ ++S RS+ + H SS
Sbjct: 230 DQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSS 289
Query: 264 SSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELS 323
S E E E+ +EK+ +R+ R ++ S S E+ +S+ R +
Sbjct: 290 SFDRELEREKERQRLEREAKEREKE-RRRSRSIDRGLERRRSRSRERHRSRSRS--RDRK 346
Query: 324 SSHHNREKAKEK------------------PRFLKHESSREDSKWSHSDSDKKSRTHK-- 363
+R++ +EK R + E SRE SK S + + + HK
Sbjct: 347 GDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKED 406
Query: 364 -----HSPEKRGSERKEGSSRSHGREERSR-RSRSRSPGSYKQRETRKRAQRNPGEEQSR 417
H +KR S++++ SRS RE + R RSRSR+ G + +++++ ++ E + +
Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEK 466
Query: 418 RNDSRSHGT 426
N G+
Sbjct: 467 SNKRSRSGS 475
Score = 67.4 bits (163), Expect = 3e-11
Identities = 48/230 (20%), Positives = 102/230 (44%), Gaps = 7/230 (3%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSS 278
+++++ R +DR ++++ + R++ + +SRS+ +K + +
Sbjct: 312 EKERRRSRSIDRGLERRRSRSRERHR-SRSRSRDRKGDRRDRDREREKENERGRRRDRDY 370
Query: 279 ESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKK--RKLHEELSSSHHNREKAKEKP 336
+ E N+ +K + + R+++K E+K K K R+ ++ S ++ ++ +
Sbjct: 371 DKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRS 430
Query: 337 RFLKHES---SREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSR 393
R KH S SR K S S S +KS HK+ +++ ++R S+ + R
Sbjct: 431 RERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREH 490
Query: 394 SPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTH 443
SP K R+ + +R+ + S D +S D R + + +E H
Sbjct: 491 SPSKEKSRKRSRSKERSHKRDHSDSKD-QSDKHDRRRSQSIEQESQEKQH 539
Score = 66.6 bits (161), Expect = 4e-11
Identities = 50/169 (29%), Positives = 83/169 (49%), Gaps = 22/169 (13%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSS 278
++K+ K DR + K+ +K+KK +SRS+ +KH+S S S ++ S S + E SS
Sbjct: 399 EEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRS-RSKEKSS 457
Query: 279 ESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRF 338
+ ++ +KEK K+++ +DS EK SKKR+ H+ K K + R
Sbjct: 458 KHKNESKEKS-----NKRSRSGSQGRTDSVEK--SKKRE---------HSPSKEKSRKRS 501
Query: 339 LKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERS 387
E S K HSDS K ++ KH + S +E + H ++ +
Sbjct: 502 RSKERSH---KRDHSDS--KDQSDKHDRRRSQSIEQESQEKQHKNKDET 545
Score = 50.4 bits (119), Expect = 3e-06
Identities = 35/126 (27%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 218 TKQKQKLLRKLDRLEK-KKKKKDRKKKKFQKSRSKHK--KHKSSSSSSSS----SSSSSS 270
+K+++K R R K + + + R K +SRSK K KHK+ S S+ S S
Sbjct: 419 SKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGR 478
Query: 271 TETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDS-EEKDKSKKRKLHEELSSSHHNR 329
T++ E S + E + ++K +++ R K + ++SDS ++ DK +R+ S +
Sbjct: 479 TDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538
Query: 330 EKAKEK 335
K K++
Sbjct: 539 HKNKDE 544
Score = 30.4 bits (67), Expect = 3.4
Identities = 20/98 (20%), Positives = 45/98 (45%), Gaps = 5/98 (5%)
Query: 214 KSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKS---RSKHKKHKSSSSSS--SSSSSS 268
K ++ K+K + + ++K K+ R + + +SK ++H S S S S
Sbjct: 446 KRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKE 505
Query: 269 SSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSD 306
S + S S+ +S+ +++ + ++++ H N D
Sbjct: 506 RSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 77.4 bits (189), Expect = 2e-14
Identities = 55/203 (27%), Positives = 100/203 (49%), Gaps = 16/203 (7%)
Query: 202 SEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSS 261
+E EE + K L K ++KLL + KK+++K ++KK KS SS
Sbjct: 59 AEFEEKMNENWKKELE-KSREKLLSGNESSSKKRERKKKRKK------------KSCRSS 105
Query: 262 SSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDK-SKKRKLHE 320
SSSSSS SS+ +S+S E + K +K ++ + K+ S + S+SE K+ KK+K +
Sbjct: 106 SSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKD 165
Query: 321 ELSSSHHNREKAKEKPRFLKHES--SREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSS 378
E R +K++ + + S E S S + D +++ + E+ ++ K
Sbjct: 166 ETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKK 225
Query: 379 RSHGREERSRRSRSRSPGSYKQR 401
+ ++ S++ + +S S+K R
Sbjct: 226 KKKQHKKHSKKKKKKSGSSHKSR 248
Score = 57.0 bits (136), Expect = 3e-08
Identities = 46/216 (21%), Positives = 85/216 (39%), Gaps = 3/216 (1%)
Query: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKK 288
D L + + + KK+ + ++ K + + + E S S + + KK
Sbjct: 32 DYLNRPRPTWEEVKKQLENKKTGSKA-LAEFEEKMNENWKKELEKSREKLLSGNESSSKK 90
Query: 289 IQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDS 348
+RKK++K K S ++S S D S E+ R K K+ + +SS +S
Sbjct: 91 RERKKKRKKK-SCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHES 149
Query: 349 KWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHG-REERSRRSRSRSPGSYKQRETRKRA 407
+ +S KK + K EK R R +++ S S S Y++ K+
Sbjct: 150 ESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKK 209
Query: 408 QRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTH 443
+R EQ++ + + K ++ G +H
Sbjct: 210 RRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSH 245
Score = 53.1 bits (126), Expect = 5e-07
Identities = 41/147 (27%), Positives = 65/147 (44%), Gaps = 7/147 (4%)
Query: 191 TANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRS 250
+++D S SE EE + + K + + E + K+ +KKKK +
Sbjct: 109 SSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETE 168
Query: 251 KHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEK 310
K K +S S S +SESSSES+ E+ +Q K KK +C ++EK
Sbjct: 169 KEKDVRSLSKKRKKSYPDDKPLSSESSSESD---YEEDVQAK--KKRRC--EEREQAKEK 221
Query: 311 DKSKKRKLHEELSSSHHNREKAKEKPR 337
K KK+K H++ S + + K R
Sbjct: 222 VKKKKKKQHKKHSKKKKKKSGSSHKSR 248
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 76.6 bits (187), Expect = 4e-14
Identities = 49/222 (22%), Positives = 94/222 (42%), Gaps = 25/222 (11%)
Query: 226 RKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNK 285
RK +R E++K+K++R+K++ ++ K KK + E E E K
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKR---------------ERGKERERKRK 80
Query: 286 EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR 345
E++ QRK+R+ + E + + K++K E R+K KE+ + R
Sbjct: 81 EREKQRKERR----------EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR 130
Query: 346 EDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRK 405
+ K K+ + K E+ ERK + RE++ R+R +++E R+
Sbjct: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
Query: 406 RAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVT 447
R + E + ++ + TD +++R +VT
Sbjct: 191 RKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVT 232
Score = 76.3 bits (186), Expect = 5e-14
Identities = 46/192 (23%), Positives = 88/192 (45%), Gaps = 9/192 (4%)
Query: 232 EKKKKKKDRKKKKFQKSRS-KHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQ 290
E+KK++++R+K+K ++ + K ++ K E E + + +K +
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
Query: 291 RKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKW 350
RK++K+ K E+ K K+RK E + R++ K + + + E RE +
Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER- 153
Query: 351 SHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRN 410
+ +K R + +KR RKE R RE + RR R + +++E RK+ +R
Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKE---RKKERERKERRERKKE----RKKERRKKKERK 206
Query: 411 PGEEQSRRNDSR 422
+ R+ DS+
Sbjct: 207 KDRKTDRQTDSQ 218
Score = 53.5 bits (127), Expect = 4e-07
Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 25/170 (14%)
Query: 269 SSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHN 328
S + S+ ++ ES K+++ +R+KRK+ E++K +KR+
Sbjct: 21 SCSHISKPCTQRESERKKERREREKRKR------------EREKERKRE--------RGK 60
Query: 329 REKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREER-S 387
+EK K K R + K + +K R K KR E+K+ + GR ER
Sbjct: 61 KEKKKRKKR---ERGKERERKRKEREKQRKERREKER-RKRKKEKKKRERKQRGRRERKK 116
Query: 388 RRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
++ R KQR RKR +R + + R + G + +K +E
Sbjct: 117 KKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166
Score = 42.0 bits (97), Expect = 0.001
Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 7/133 (5%)
Query: 319 HEELSSSHHNREKAKEKPRFLKHESSRE-DSKWSHSDSDKKSRTHKHSPEKRGSERKEGS 377
H + E+ KE+ K + RE + K +KK R + ++R +RKE
Sbjct: 24 HISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83
Query: 378 SRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
+ R E+ RR R K+++ R+R QR E + ++ + R E+ ++
Sbjct: 84 KQRKERREKERRKRK------KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137
Query: 438 HPGGTHTKVTQRE 450
K +RE
Sbjct: 138 RRKKKRRKERKRE 150
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 75.5 bits (184), Expect = 9e-14
Identities = 71/217 (32%), Positives = 95/217 (43%), Gaps = 21/217 (9%)
Query: 229 DRLEKKKKKKDRKKKKFQKSRS---KHKKHKSSSSSSSSSSSSSSTETSESSSESESNNK 285
D L +K DR KKK Q S + KH S S S S ++ S S +K
Sbjct: 9 DGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSK 68
Query: 286 EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR 345
E + K K +K H + + +K+ S K E L+SS + ++ K K R +SSR
Sbjct: 69 EGRRHESKDKSSK--KHKSEEHNDKEHSSD-KGRERLNSSENGEDRHKRKER----KSSR 121
Query: 346 EDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRK 405
S HS S + R H+ R ERK+ SRS R++ RSR R + RE RK
Sbjct: 122 GRS---HSRSRSRERRHR----SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRE-RK 173
Query: 406 RAQRNPGEEQSR---RNDSRSHGTDLYRGEKMYREHP 439
R R+ +SR R SRS R K E P
Sbjct: 174 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKP 210
Score = 71.2 bits (173), Expect = 2e-12
Identities = 57/192 (29%), Positives = 95/192 (49%), Gaps = 21/192 (10%)
Query: 236 KKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRK 295
+ + R +++ +KS ++ +KH+S S S S ++S+ E N+KE + + +
Sbjct: 42 RSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRER 101
Query: 296 KNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDS 355
N ++ + E++ K K+RK S H+R +++E+ +H S + K S S
Sbjct: 102 LN-----SSENGEDRHKRKERKSSRGRS---HSRSRSRER----RHRSRSRERKKSRS-- 147
Query: 356 DKKSRTHKHSPEKRGSERKEGSSRSHGREERSR-RSRSRSPGSYKQR---ETRKRAQRNP 411
+SR K S R ERK+ SRS R+ R R RSRSRS ++ R TR R++
Sbjct: 148 --RSRERKKS-RSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRK 204
Query: 412 GEEQSRRNDSRS 423
+ R SRS
Sbjct: 205 KRIEKPRRFSRS 216
Score = 63.2 bits (152), Expect = 5e-10
Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 24/187 (12%)
Query: 267 SSSSTETSESSSESESNNKEKKIQRKKRKKN-KCSGHNNSDSEEKDKSKKRKLHEELSSS 325
++S TE + E S +++KK ++ + + + S H+ S S + + +KRK E
Sbjct: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNE-GRK 60
Query: 326 HHNREKAKEKPRF-LKHESSREDSKWSHSD----SDK--------KSRTHKHSPEKRGSE 372
H +R ++KE R K +SS++ H+D SDK ++ +H ++R S
Sbjct: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
Query: 373 RKEGSSRSHGREERSR---------RSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRS 423
R SRS RE R R RSRSR + R ++ R+ E+ RR SRS
Sbjct: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
Query: 424 HGTDLYR 430
+R
Sbjct: 181 RSRSRHR 187
Score = 56.6 bits (135), Expect = 4e-08
Identities = 65/255 (25%), Positives = 104/255 (40%), Gaps = 53/255 (20%)
Query: 182 KRNVLGRNLTANDPSQEYVASEGEEDPEVE---FLKSLTTKQKQKLLRKLDRLEKKKKKK 238
+R+ L T+ D ++ SE P + +S + +++K RK D +K + +
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERK--RKSDNEGRKHRSR 64
Query: 239 DRKK--KKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESS------------------S 278
R K ++ + KKHKS + SS E SS S
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
Query: 279 ESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRF 338
S S ++E++ + + R++ K + S S E+ KS+ R +RE+ K + R
Sbjct: 125 HSRSRSRERRHRSRSRERKK----SRSRSRERKKSRSR-----------SRERKKSRSR- 168
Query: 339 LKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRR-----SRSR 393
SRE + S S +SR H+H R R R R E+ RR SR+
Sbjct: 169 -----SRERKRRIRSRSRSRSR-HRHRTRSRSRTRSRSRDRKK-RIEKPRRFSRSLSRTP 221
Query: 394 SPGSYKQRETRKRAQ 408
SP ++ R T AQ
Sbjct: 222 SPPPFRGRNTAMDAQ 236
Score = 39.7 bits (91), Expect = 0.006
Identities = 33/124 (26%), Positives = 61/124 (49%), Gaps = 15/124 (12%)
Query: 226 RKLDRLEKKKKKKDRKK-KKFQKSRSKHKKHKSSSSSSSSSSSSSSTET-SESSSESESN 283
RK R +++KK R + ++ +KSRS+ ++ K S S S S T S S + S S
Sbjct: 142 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201
Query: 284 NKEKKIQRKKRKKNKCS---------GHNNS-DSEE---KDKSKKRKLHEELSSSHHNRE 330
+++K+I++ +R S G N + D++E + + +KL E+ ++
Sbjct: 202 DRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQ 261
Query: 331 KAKE 334
K +E
Sbjct: 262 KQQE 265
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 71.2 bits (173), Expect = 2e-12
Identities = 59/262 (22%), Positives = 116/262 (44%), Gaps = 11/262 (4%)
Query: 180 ALKRNVLGRNLTANDPSQEYVASEGEEDPEVEF-LKSLTTKQKQKLLRKLDRLEKKKKKK 238
+L + L + ++ DP +VA+ G P ++ S ++ K +R+ L +
Sbjct: 181 SLAADQLLKLMSTVDPKLNHVAA-GLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEP 239
Query: 239 DRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKK----- 293
D+K++K + SRS+ + + + SSS S S S S+S S + K +R++
Sbjct: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE 299
Query: 294 --RKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWS 351
R+ S + E+K+K + + + S++ +R ++E+ R +R K
Sbjct: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKK-P 358
Query: 352 HSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNP 411
S K SR+ K+ ++ + RS ERS + +S K RE + + ++
Sbjct: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDV 418
Query: 412 GEEQSRRNDSRSHGTDLYRGEK 433
++ +R D G D + +K
Sbjct: 419 -KQVTRDYDEEEQGYDSEKEKK 439
Score = 58.5 bits (140), Expect = 1e-08
Identities = 49/171 (28%), Positives = 78/171 (45%), Gaps = 13/171 (7%)
Query: 230 RLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKI 289
R K +D+KK+ +K RSK S S++ S S+S E S S + + +K
Sbjct: 303 RSRSTSKTRDKKKEDKEKKRSKTPP---KSYSTARRSRSASRERRRRRSRSGTRSPKKPR 359
Query: 290 QRKKRKKNKCSGHNNSDSEEKDKSKKRKLHE-ELSSSHHNREKAKEKPRFLKHESSRE-- 346
K++ S + ++KDK K+R E E S+S + K KEK R K ES ++
Sbjct: 360 SPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVK 419
Query: 347 ------DSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSR 391
D + DS+K+ + K P + GS + + S G + R S+
Sbjct: 420 QVTRDYDEEEQGYDSEKEKKEEK-KPIETGSPKTKECSVEKGTGDSLRESK 469
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 8/147 (5%)
Query: 217 TTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSES 276
T+K + K +K D+ +K+ K + ++SRS ++ + S S + S
Sbjct: 307 TSKTRDK--KKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRK 364
Query: 277 SSESESNNKEKKIQRKKRKKNKC------SGHNNSDSEEKDKSKKRKLHEELSSSHHNRE 330
S S S + KK ++K + K + S S++K+K ++RK + R+
Sbjct: 365 LSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRD 424
Query: 331 KAKEKPRFLKHESSREDSKWSHSDSDK 357
+E+ + + +E+ K + S K
Sbjct: 425 YDEEEQGYDSEKEKKEEKKPIETGSPK 451
Score = 38.1 bits (87), Expect = 0.016
Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 8/118 (6%)
Query: 221 KQKLLRKLD-RLEKKKKKKDRKKKKF--QKSRSKHKKHKSSSSSSSSSSSSSSTE----- 272
K+KL R R KK+KKKD+ K++ ++ RS KK KS S S +
Sbjct: 362 KRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQV 421
Query: 273 TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNRE 330
T + E + + EK+ + +K+ S S EK + + HH +
Sbjct: 422 TRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEED 479
Score = 36.2 bits (82), Expect = 0.062
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSES-S 277
K+++K + +R ++++ KKKK K + K ++ KS S + E +
Sbjct: 375 KKEKKKDKDKERSRDERERSTSKKKK-SKDKEKDRERKSESDKDVKQVTRDYDEEEQGYD 433
Query: 278 SESESNNKEKKIQRKKRKKNKCSGHNNS-DSEEKDKSKKRKLHEE 321
SE E ++K I+ K +CS + DS + K HEE
Sbjct: 434 SEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEE 478
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 71.2 bits (173), Expect = 2e-12
Identities = 58/192 (30%), Positives = 85/192 (44%), Gaps = 18/192 (9%)
Query: 202 SEGEEDPEVEFLKSLTTKQKQKL----LRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKS 257
SEGEE+ E E L + + L K + L+ +++ KKK ++SRSK + S
Sbjct: 153 SEGEEEDEDEDLSKYKLDEDEDEDDADLSKYN-LDASEEEDSNKKKSNRRSRSKSRSSHS 211
Query: 258 SSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRK 317
SSS SSS SSS + + S S S+ + ++R +++ S +S + S RK
Sbjct: 212 RSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRK 271
Query: 318 LHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGS 377
SSS R + R S+ S S KK RT SPE+R GS
Sbjct: 272 RSYSSSSSSPERNR------------KRSRSRSSSSGDRKKRRTRSRSPERR-HRSSSGS 318
Query: 378 SRSHGREERSRR 389
S S R ++
Sbjct: 319 SHSGSRSSSKKK 330
Score = 66.6 bits (161), Expect = 4e-11
Identities = 68/232 (29%), Positives = 102/232 (43%), Gaps = 25/232 (10%)
Query: 198 EYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRL-EKKKKKKDRKKKKFQKSRSKHKKHK 256
EY+ E E D E + K + K + L E + K+ + +++ + SK+K +
Sbjct: 113 EYIERE-ESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDE 171
Query: 257 SSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKR 316
+ S + +SE E +NK KK R+ R K++ S H+ S S S R
Sbjct: 172 DEDEDDADLSKYNL-----DASEEEDSNK-KKSNRRSRSKSR-SSHSRSSSRSSSPSSSR 224
Query: 317 KLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEG 376
S +R ++ + SSRE S+ S S SR+H+ S S RK
Sbjct: 225 -------SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGS----SSPRKRS 273
Query: 377 SSRSHGREERSR---RSRSRSPGSYKQRETRKRA--QRNPGEEQSRRNDSRS 423
S S ER+R RSRS S G K+R TR R+ +R+ S + SRS
Sbjct: 274 YSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRS 325
Score = 63.9 bits (154), Expect = 3e-10
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 17/217 (7%)
Query: 234 KKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKK 293
++++ D + +F + + K++ +S +E E E E +K K + +
Sbjct: 116 EREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESE-GEEEDEDEDLSKYKLDEDED 174
Query: 294 RKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHS 353
S +N SEE+D +KK+ S S + ++ + SR S+ S S
Sbjct: 175 EDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSR-SRS 233
Query: 354 DSDKKSRTHKHSPEK---RGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQ-- 408
S +SR+ S E+ RGS+ + SSRSH R S R RS S S RKR++
Sbjct: 234 SSSSQSRSRSSSRERSRSRGSKSRS-SSRSH-RGSSSPRKRSYSSSSSSPERNRKRSRSR 291
Query: 409 -RNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHT 444
+ G+ + RR SRS E+ +R G +H+
Sbjct: 292 SSSSGDRKKRRTRSRS-------PERRHRSSSGSSHS 321
Score = 32.0 bits (71), Expect = 1.2
Identities = 41/168 (24%), Positives = 71/168 (42%), Gaps = 32/168 (19%)
Query: 272 ETSESSSESESNNKEKKIQRKKRK-KNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNRE 330
E E ES+ + + RKK+K + K G + E +DK + + +E + +
Sbjct: 110 ENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDE------DED 163
Query: 331 KAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRS 390
+K K L + +D+ S + D + E+ S +K+ + RRS
Sbjct: 164 LSKYK---LDEDEDEDDADLSKYNLD--------ASEEEDSNKKKSN----------RRS 202
Query: 391 RSRSPGSYKQRETRKRAQRNPGEEQSR-RNDSRSHGTDLYRGEKMYRE 437
RS+S S+ + +R +P +SR R+ SRS + R RE
Sbjct: 203 RSKSRSSHSRSSSR---SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRE 247
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 71.2 bits (173), Expect = 2e-12
Identities = 46/190 (24%), Positives = 91/190 (47%), Gaps = 14/190 (7%)
Query: 211 EFLKSLTTKQKQKLLRKLDRL----EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSS 266
EF + + K++L + ++L E KK+ RKKK+ KK SSSSSSS
Sbjct: 50 EFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKE--------KKKSGRYSSSSSSS 101
Query: 267 SSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSH 326
S SS+ +S+S E + K +K ++ + K+ S + ++S+ KD KK+K ++ +
Sbjct: 102 SDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKE 161
Query: 327 HNREKAKEKPRFLKHESSREDSKWSHSD--SDKKSRTHKHSPEKRGSERKEGSSRSHGRE 384
+ + +K + + S S+ + +++ K S E+ + K + H +
Sbjct: 162 KDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKH 221
Query: 385 ERSRRSRSRS 394
+ ++ ++ S
Sbjct: 222 SKKKKKKAAS 231
Score = 65.9 bits (159), Expect = 7e-11
Identities = 60/185 (32%), Positives = 85/185 (45%), Gaps = 24/185 (12%)
Query: 202 SEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKK-KKKDRKKKKFQKSRSKHKKHKSSSS 260
+E EE + K L K ++KLL + KK+ +KK KKK ++ SSSS
Sbjct: 49 AEFEEKMNENWKKELE-KHREKLLSGSESSSKKRQRKKKEKKKS-----GRYSSSSSSSS 102
Query: 261 SSSSSSSSSSTE-------------TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDS 307
SSSSSS S E S SSES + E + +KK K +
Sbjct: 103 DSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEK 162
Query: 308 EEKDKSKKRKLHEE---LSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKH 364
+ K SKKRK++ E LSS + + E+ R K +SS E K + + KK + KH
Sbjct: 163 DIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREK-ATEKTKKKKKHKKH 221
Query: 365 SPEKR 369
S +K+
Sbjct: 222 SKKKK 226
Score = 54.3 bits (129), Expect = 2e-07
Identities = 43/133 (32%), Positives = 64/133 (48%), Gaps = 17/133 (12%)
Query: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKK 288
D ++ KK+ R+KKK K++ HKSS SS S + S S + + KEK
Sbjct: 110 DSEDEDKKQGKRRKKK------KNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 163
Query: 289 IQ--RKKRK----KNKCSGHNNSDSE--EKDKSKKRKLHEELSSSHHNREKAKEKPRFLK 340
I+ KKRK S + S+SE E+ ++KK+K EE + EK K+K + K
Sbjct: 164 IKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKA---TEKTKKKKKHKK 220
Query: 341 HESSREDSKWSHS 353
H ++ S S
Sbjct: 221 HSKKKKKKAASSS 233
Score = 47.0 bits (110), Expect = 4e-05
Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 2/121 (1%)
Query: 287 KKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR- 345
K+ KK+K +K E K + K E+L S + K +++ + K +S R
Sbjct: 35 KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRY 94
Query: 346 EDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERS-RRSRSRSPGSYKQRETR 404
S S SDS S + +K+G RK+ +RSH E S + S S S K+++
Sbjct: 95 SSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS 154
Query: 405 K 405
K
Sbjct: 155 K 155
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 12/91 (13%)
Query: 229 DRLEKKKKKKD-RKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSE-------SSSE- 279
D L+KKKK KD +K+K K SK +K S SS S S S E SS E
Sbjct: 146 DSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEER 205
Query: 280 ---SESNNKEKKIQRKKRKKNKCSGHNNSDS 307
+E K+KK ++ +KK K + ++ DS
Sbjct: 206 EKATEKTKKKKKHKKHSKKKKKKAASSSPDS 236
Score = 40.0 bits (92), Expect = 0.004
Identities = 36/150 (24%), Positives = 67/150 (44%), Gaps = 15/150 (10%)
Query: 187 GRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQ 246
GR +++ S + +S + + E + + K+K+ K + + D K +
Sbjct: 92 GRYSSSSSSSSDSSSSSSDSEDE-DKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKK 150
Query: 247 KSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSD 306
K +SK K S +E SSES S ++ + R K+KK +S+
Sbjct: 151 KKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK-------SSE 203
Query: 307 SEEK--DKSKKRKLHEELSSSHHNREKAKE 334
EK +K+KK+K H++ H+++K K+
Sbjct: 204 EREKATEKTKKKKKHKK-----HSKKKKKK 228
Score = 34.7 bits (78), Expect = 0.18
Identities = 54/245 (22%), Positives = 94/245 (38%), Gaps = 50/245 (20%)
Query: 29 EQKISYDKKK---------QEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGAK 79
E K +KKK +E++ + + KE E + +LL G E +K
Sbjct: 33 EVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES-------------SSK 79
Query: 80 KENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNT 139
K ++K+E + Y + + D + D+ G + R + + HK
Sbjct: 80 KRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSED-EDKKQGKR-RKKKKNRSHK------ 131
Query: 140 DRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQEY 199
S ++ S S S+ + G ++++ G + S++
Sbjct: 132 ---------SSESSMSETESDSKDSLKKKK----KSKDGTEKEKDIKGLSKKRKMYSEDK 178
Query: 200 VASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSS 259
S E E E+++ + K+K+ + EK KKKK KK SK KK K++S
Sbjct: 179 PLSS-ESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKK------HSKKKKKKAAS 231
Query: 260 SSSSS 264
SS S
Sbjct: 232 SSPDS 236
Score = 33.9 bits (76), Expect = 0.31
Identities = 14/46 (30%), Positives = 25/46 (54%)
Query: 228 LDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTET 273
++ + KKKK +++K + K KKHK S ++SSS ++
Sbjct: 191 IEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDS 236
Score = 33.5 bits (75), Expect = 0.40
Identities = 25/137 (18%), Positives = 49/137 (35%), Gaps = 7/137 (5%)
Query: 308 EEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPE 367
++K SK EE + + +E K + + L S + KKS + S
Sbjct: 40 KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSS 99
Query: 368 KRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTD 427
S +++ +R + + S+K E+ + ++ ++ GT+
Sbjct: 100 SSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTE 159
Query: 428 -------LYRGEKMYRE 437
L + KMY E
Sbjct: 160 KEKDIKGLSKKRKMYSE 176
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 71.2 bits (173), Expect = 2e-12
Identities = 46/190 (24%), Positives = 91/190 (47%), Gaps = 14/190 (7%)
Query: 211 EFLKSLTTKQKQKLLRKLDRL----EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSS 266
EF + + K++L + ++L E KK+ RKKK+ KK SSSSSSS
Sbjct: 60 EFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKE--------KKKSGRYSSSSSSS 111
Query: 267 SSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSH 326
S SS+ +S+S E + K +K ++ + K+ S + ++S+ KD KK+K ++ +
Sbjct: 112 SDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKE 171
Query: 327 HNREKAKEKPRFLKHESSREDSKWSHSD--SDKKSRTHKHSPEKRGSERKEGSSRSHGRE 384
+ + +K + + S S+ + +++ K S E+ + K + H +
Sbjct: 172 KDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKH 231
Query: 385 ERSRRSRSRS 394
+ ++ ++ S
Sbjct: 232 SKKKKKKAAS 241
Score = 65.9 bits (159), Expect = 7e-11
Identities = 60/185 (32%), Positives = 85/185 (45%), Gaps = 24/185 (12%)
Query: 202 SEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKK-KKKDRKKKKFQKSRSKHKKHKSSSS 260
+E EE + K L K ++KLL + KK+ +KK KKK ++ SSSS
Sbjct: 59 AEFEEKMNENWKKELE-KHREKLLSGSESSSKKRQRKKKEKKKS-----GRYSSSSSSSS 112
Query: 261 SSSSSSSSSSTE-------------TSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDS 307
SSSSSS S E S SSES + E + +KK K +
Sbjct: 113 DSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEK 172
Query: 308 EEKDKSKKRKLHEE---LSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKH 364
+ K SKKRK++ E LSS + + E+ R K +SS E K + + KK + KH
Sbjct: 173 DIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREK-ATEKTKKKKKHKKH 231
Query: 365 SPEKR 369
S +K+
Sbjct: 232 SKKKK 236
Score = 54.3 bits (129), Expect = 2e-07
Identities = 43/133 (32%), Positives = 64/133 (48%), Gaps = 17/133 (12%)
Query: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKK 288
D ++ KK+ R+KKK K++ HKSS SS S + S S + + KEK
Sbjct: 120 DSEDEDKKQGKRRKKK------KNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 173
Query: 289 IQ--RKKRK----KNKCSGHNNSDSE--EKDKSKKRKLHEELSSSHHNREKAKEKPRFLK 340
I+ KKRK S + S+SE E+ ++KK+K EE + EK K+K + K
Sbjct: 174 IKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKA---TEKTKKKKKHKK 230
Query: 341 HESSREDSKWSHS 353
H ++ S S
Sbjct: 231 HSKKKKKKAASSS 243
Score = 47.0 bits (110), Expect = 4e-05
Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 2/121 (1%)
Query: 287 KKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR- 345
K+ KK+K +K E K + K E+L S + K +++ + K +S R
Sbjct: 45 KEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRY 104
Query: 346 EDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERS-RRSRSRSPGSYKQRETR 404
S S SDS S + +K+G RK+ +RSH E S + S S S K+++
Sbjct: 105 SSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS 164
Query: 405 K 405
K
Sbjct: 165 K 165
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 12/91 (13%)
Query: 229 DRLEKKKKKKD-RKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSE-------SSSE- 279
D L+KKKK KD +K+K K SK +K S SS S S S E SS E
Sbjct: 156 DSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEER 215
Query: 280 ---SESNNKEKKIQRKKRKKNKCSGHNNSDS 307
+E K+KK ++ +KK K + ++ DS
Sbjct: 216 EKATEKTKKKKKHKKHSKKKKKKAASSSPDS 246
Score = 40.0 bits (92), Expect = 0.004
Identities = 36/150 (24%), Positives = 67/150 (44%), Gaps = 15/150 (10%)
Query: 187 GRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQ 246
GR +++ S + +S + + E + + K+K+ K + + D K +
Sbjct: 102 GRYSSSSSSSSDSSSSSSDSEDE-DKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKK 160
Query: 247 KSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSD 306
K +SK K S +E SSES S ++ + R K+KK +S+
Sbjct: 161 KKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK-------SSE 213
Query: 307 SEEK--DKSKKRKLHEELSSSHHNREKAKE 334
EK +K+KK+K H++ H+++K K+
Sbjct: 214 EREKATEKTKKKKKHKK-----HSKKKKKK 238
Score = 34.7 bits (78), Expect = 0.18
Identities = 54/245 (22%), Positives = 94/245 (38%), Gaps = 50/245 (20%)
Query: 29 EQKISYDKKK---------QEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGAK 79
E K +KKK +E++ + + KE E + +LL G E +K
Sbjct: 43 EVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES-------------SSK 89
Query: 80 KENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNT 139
K ++K+E + Y + + D + D+ G + R + + HK
Sbjct: 90 KRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSED-EDKKQGKR-RKKKKNRSHK------ 141
Query: 140 DRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQEY 199
S ++ S S S+ + G ++++ G + S++
Sbjct: 142 ---------SSESSMSETESDSKDSLKKKK----KSKDGTEKEKDIKGLSKKRKMYSEDK 188
Query: 200 VASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSS 259
S E E E+++ + K+K+ + EK KKKK KK SK KK K++S
Sbjct: 189 PLSS-ESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKK------HSKKKKKKAAS 241
Query: 260 SSSSS 264
SS S
Sbjct: 242 SSPDS 246
Score = 33.9 bits (76), Expect = 0.31
Identities = 14/46 (30%), Positives = 25/46 (54%)
Query: 228 LDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTET 273
++ + KKKK +++K + K KKHK S ++SSS ++
Sbjct: 201 IEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDS 246
Score = 33.5 bits (75), Expect = 0.40
Identities = 25/137 (18%), Positives = 49/137 (35%), Gaps = 7/137 (5%)
Query: 308 EEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPE 367
++K SK EE + + +E K + + L S + KKS + S
Sbjct: 50 KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSS 109
Query: 368 KRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTD 427
S +++ +R + + S+K E+ + ++ ++ GT+
Sbjct: 110 SSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTE 169
Query: 428 -------LYRGEKMYRE 437
L + KMY E
Sbjct: 170 KEKDIKGLSKKRKMYSE 186
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 71.2 bits (173), Expect = 2e-12
Identities = 56/227 (24%), Positives = 112/227 (49%), Gaps = 33/227 (14%)
Query: 197 QEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHK--- 253
+E + EE E LK K+KQ+ + E+++++++RK+++ ++ R K +
Sbjct: 231 KEKLRKRTEEPDRDERLK----KEKQEREEREKEREREREERERKRRREEEEREKERARD 286
Query: 254 --KHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKD 311
+ K S S S SS +S S S S ++E++ + + R + + H+ S+ + +
Sbjct: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERR-RSRSRDRRRSRSHDRSERKHRS 345
Query: 312 KSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGS 371
+S+ R+ R K++++ + KH S D + D+KS+ EKRGS
Sbjct: 346 RSRDRR-----------RSKSRDRKSY-KHRSKSRD-----REQDRKSK----EKEKRGS 384
Query: 372 ERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQ--RNPGEEQS 416
+ K+ S +S RE++S + + S S + E ++ ++ G+ QS
Sbjct: 385 DDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
Score = 67.4 bits (163), Expect = 3e-11
Identities = 39/151 (25%), Positives = 76/151 (50%), Gaps = 6/151 (3%)
Query: 280 SESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFL 339
+E +++++++++K+++ + + EE+++ ++R+ E +RE+ K
Sbjct: 238 TEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRS 297
Query: 340 KHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYK 399
+H S D + S S K+SR+ + +R R SRSH R ER RSRSR K
Sbjct: 298 RHSSRTSDRRCSRSRDHKRSRSRE---RRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSK 354
Query: 400 QRETR--KRAQRNPGEEQSRRN-DSRSHGTD 427
R+ + K ++ EQ R++ + G+D
Sbjct: 355 SRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 10/141 (7%)
Query: 287 KKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSRE 346
++++ K RK+ + + + ++ KK K E RE+ + + + + E RE
Sbjct: 228 EELKEKLRKRTE-------EPDRDERLKKEKQEREEREKEREREREERERKRRREEEERE 280
Query: 347 DSKWSHSDSDKKSRT---HKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRET 403
+ + K+SR+ H R R RS RE R RSR R R
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 404 RKRAQRNPGEEQSRRNDSRSH 424
RK R+ +S+ D +S+
Sbjct: 341 RKHRSRSRDRRRSKSRDRKSY 361
Score = 45.8 bits (107), Expect = 8e-05
Identities = 56/259 (21%), Positives = 105/259 (40%), Gaps = 17/259 (6%)
Query: 190 LTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSR 249
L+ N S G+ + +++ L T + LL++++ L + K ++ + +
Sbjct: 109 LSQNQQSSGAAGPTGKNEEKIQVL----TDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQ 164
Query: 250 SKHKKHKSSSSSSSSSSSSSSTETSESSSESES----NNKEKKIQRKKRKKNKCSGHNNS 305
K ++ S++S+ S ++ + E + + + ++ K
Sbjct: 165 LKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIK 224
Query: 306 DSEEKDKSKKRKLHEELSSSHH-NREKAKEKPRFLKHESSRED---SKWSHSDSDKKSRT 361
+ E+ K K RK EE +EK + + R + E RE+ + + +K R
Sbjct: 225 ATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERA 284
Query: 362 HKHSPEKRGSERKEGSSRSHGRE-ERSR---RSRSRSPGSYKQRETRKRAQRNPGEEQSR 417
KR R SSR+ R RSR RSRSR + R+ R+R++ + E+
Sbjct: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD-RRRSRSHDRSERKH 343
Query: 418 RNDSRSHGTDLYRGEKMYR 436
R+ SR R K Y+
Sbjct: 344 RSRSRDRRRSKSRDRKSYK 362
Score = 40.4 bits (93), Expect = 0.003
Identities = 59/275 (21%), Positives = 98/275 (35%), Gaps = 56/275 (20%)
Query: 18 SKSNIKKVWMAEQKISYDKKKQ--EELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAP 75
++S + M +Q + Y K K EEL ++ K E D DER+K E
Sbjct: 204 AQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDR-----DERLKKEKQEREERE 258
Query: 76 PGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWG 135
++E +E+E E + E ++ RE R R +
Sbjct: 259 KEREREREERERKRRREEEEREKERARDRE------------------RRKRSRSRSRHS 300
Query: 136 HVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDP 195
+DR C S H E R S R+ R ++D
Sbjct: 301 SRTSDRRC-----------------SRSRDHKRSRSRERRRS-----RSRDRRRSRSHDR 338
Query: 196 SQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKH 255
S+ S + + + K + K + +++DRK K+ +K S KK
Sbjct: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSK---------SRDREQDRKSKEKEKRGSDDKKS 389
Query: 256 KSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQ 290
S S S ++TE+ ES +++E N + I+
Sbjct: 390 SVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIK 424
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 71.2 bits (173), Expect = 2e-12
Identities = 56/227 (24%), Positives = 112/227 (49%), Gaps = 33/227 (14%)
Query: 197 QEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHK--- 253
+E + EE E LK K+KQ+ + E+++++++RK+++ ++ R K +
Sbjct: 231 KEKLRKRTEEPDRDERLK----KEKQEREEREKEREREREERERKRRREEEEREKERARD 286
Query: 254 --KHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKD 311
+ K S S S SS +S S S S ++E++ + + R + + H+ S+ + +
Sbjct: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERR-RSRSRDRRRSRSHDRSERKHRS 345
Query: 312 KSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGS 371
+S+ R+ R K++++ + KH S D + D+KS+ EKRGS
Sbjct: 346 RSRDRR-----------RSKSRDRKSY-KHRSKSRD-----REQDRKSK----EKEKRGS 384
Query: 372 ERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQ--RNPGEEQS 416
+ K+ S +S RE++S + + S S + E ++ ++ G+ QS
Sbjct: 385 DDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
Score = 67.4 bits (163), Expect = 3e-11
Identities = 39/151 (25%), Positives = 76/151 (50%), Gaps = 6/151 (3%)
Query: 280 SESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFL 339
+E +++++++++K+++ + + EE+++ ++R+ E +RE+ K
Sbjct: 238 TEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRS 297
Query: 340 KHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYK 399
+H S D + S S K+SR+ + +R R SRSH R ER RSRSR K
Sbjct: 298 RHSSRTSDRRCSRSRDHKRSRSRE---RRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSK 354
Query: 400 QRETR--KRAQRNPGEEQSRRN-DSRSHGTD 427
R+ + K ++ EQ R++ + G+D
Sbjct: 355 SRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 10/141 (7%)
Query: 287 KKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSRE 346
++++ K RK+ + + + ++ KK K E RE+ + + + + E RE
Sbjct: 228 EELKEKLRKRTE-------EPDRDERLKKEKQEREEREKEREREREERERKRRREEEERE 280
Query: 347 DSKWSHSDSDKKSRT---HKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRET 403
+ + K+SR+ H R R RS RE R RSR R R
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 404 RKRAQRNPGEEQSRRNDSRSH 424
RK R+ +S+ D +S+
Sbjct: 341 RKHRSRSRDRRRSKSRDRKSY 361
Score = 45.8 bits (107), Expect = 8e-05
Identities = 56/259 (21%), Positives = 105/259 (40%), Gaps = 17/259 (6%)
Query: 190 LTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSR 249
L+ N S G+ + +++ L T + LL++++ L + K ++ + +
Sbjct: 109 LSQNQQSSGAAGPTGKNEEKIQVL----TDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQ 164
Query: 250 SKHKKHKSSSSSSSSSSSSSSTETSESSSESES----NNKEKKIQRKKRKKNKCSGHNNS 305
K ++ S++S+ S ++ + E + + + ++ K
Sbjct: 165 LKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIK 224
Query: 306 DSEEKDKSKKRKLHEELSSSHH-NREKAKEKPRFLKHESSRED---SKWSHSDSDKKSRT 361
+ E+ K K RK EE +EK + + R + E RE+ + + +K R
Sbjct: 225 ATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERA 284
Query: 362 HKHSPEKRGSERKEGSSRSHGRE-ERSR---RSRSRSPGSYKQRETRKRAQRNPGEEQSR 417
KR R SSR+ R RSR RSRSR + R+ R+R++ + E+
Sbjct: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD-RRRSRSHDRSERKH 343
Query: 418 RNDSRSHGTDLYRGEKMYR 436
R+ SR R K Y+
Sbjct: 344 RSRSRDRRRSKSRDRKSYK 362
Score = 40.4 bits (93), Expect = 0.003
Identities = 59/275 (21%), Positives = 98/275 (35%), Gaps = 56/275 (20%)
Query: 18 SKSNIKKVWMAEQKISYDKKKQ--EELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAP 75
++S + M +Q + Y K K EEL ++ K E D DER+K E
Sbjct: 204 AQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDR-----DERLKKEKQEREERE 258
Query: 76 PGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWG 135
++E +E+E E + E ++ RE R R +
Sbjct: 259 KEREREREERERKRRREEEEREKERARDRE------------------RRKRSRSRSRHS 300
Query: 136 HVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDP 195
+DR C S H E R S R+ R ++D
Sbjct: 301 SRTSDRRC-----------------SRSRDHKRSRSRERRRS-----RSRDRRRSRSHDR 338
Query: 196 SQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKH 255
S+ S + + + K + K + +++DRK K+ +K S KK
Sbjct: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSK---------SRDREQDRKSKEKEKRGSDDKKS 389
Query: 256 KSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQ 290
S S S ++TE+ ES +++E N + I+
Sbjct: 390 SVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIK 424
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 69.3 bits (168), Expect = 7e-12
Identities = 39/201 (19%), Positives = 87/201 (43%), Gaps = 1/201 (0%)
Query: 203 EGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSS 262
E E D + + + +++Q ++ R E+ ++ + +++++ ++ R + + K
Sbjct: 263 ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE 322
Query: 263 SSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEEL 322
ET E E E K K+ R++N+ +G E+++ ++R+ +
Sbjct: 323 RERERERQRET-ERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381
Query: 323 SSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHG 382
+ RE+ +++ R + E E + +++K+ K +RG ER + G
Sbjct: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
Query: 383 REERSRRSRSRSPGSYKQRET 403
RE R R G ++R T
Sbjct: 442 RERDRERQTDRQAGRQRKRST 462
Score = 67.0 bits (162), Expect = 3e-11
Identities = 38/212 (17%), Positives = 90/212 (42%)
Query: 226 RKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNK 285
R+ DR ++++K+R ++K ++ ++ + + + +E E +++ +
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166
Query: 286 EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR 345
++ + R+K + N + E+++ ++++ E S RE+ +E+ + E R
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226
Query: 346 EDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRK 405
+ + + K + +R SER+ + RE R R R +++ RK
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Query: 406 RAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
R +R + ++ R R + R RE
Sbjct: 287 RQRRTERDRETERKRERQRERERERERNRKRE 318
Score = 65.5 bits (158), Expect = 1e-10
Identities = 43/232 (18%), Positives = 104/232 (44%), Gaps = 8/232 (3%)
Query: 203 EGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSS 262
E E + E + T ++++ + +R ++++++K+R++++ ++ R + K++K+ S
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR-ERERQREKENKTEDRHS 206
Query: 263 SSSSSSSSTETSESSSESE-SNNKEKKIQRK-KRKKNKCSGHNNSDSEEKDKSKKRKLHE 320
+E+ +E + ++E+ QRK +R++ K + + E ++ K+R+
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 321 ELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRS 380
+ R+K +E+ K + E + + +++ + R ER+ R
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 381 HGREERSRRSRSRSPGSYKQRETRKRAQRN-----PGEEQSRRNDSRSHGTD 427
R+ + R R + ++R+T +RN G Q+ R R D
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERD 378
Score = 63.2 bits (152), Expect = 5e-10
Identities = 41/203 (20%), Positives = 85/203 (41%), Gaps = 17/203 (8%)
Query: 253 KKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDK 312
++ S S + + ++ + KE++ +R+KR+ + + EKD+
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 313 SKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSE 372
+KR H E R++ KE+ R E R+ K + +++ T + +RG +
Sbjct: 88 HRKRDRHRE-----RQRDREKERERQTDRERDRQREKERNRQKERERETEREG--ERGRD 140
Query: 373 RKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRR----------NDSR 422
R+ R R+ + + R R +QR+T + Q+ E++R+ +++
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 423 SHGTDLYRGEKMYREHPGGTHTK 445
+ RG + RE T T+
Sbjct: 201 TEDRHSERGRERERERETETETE 223
Score = 63.2 bits (152), Expect = 5e-10
Identities = 57/283 (20%), Positives = 111/283 (39%), Gaps = 22/283 (7%)
Query: 189 NLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDR-------- 240
N T + S+ E E + E E + T +++ RK +R +K+ +++R
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
Query: 241 -KKKKFQKSRSK-----HKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKR 294
K+++ ++ R + K+ + + + ET +E++ RK+
Sbjct: 259 DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRE 318
Query: 295 KKNKCSGHNNSDSE-----EKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSK 349
++ + E EK++ +KRK E+ NR+ +E R + E RE +
Sbjct: 319 RERERERERERQRETERDREKERERKRKRQTEM-DRERNRQTGREGRRQAERERERERER 377
Query: 350 WSHSDSDKKSRTHKHSPEK-RGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQ 408
S +++ R ++ + ER+ R RE +R R + S + RE + +
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 409 RNPGEEQSR-RNDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE 450
+ G E+ R R R G R P + V Q +
Sbjct: 438 KQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSD 480
Score = 62.8 bits (151), Expect = 6e-10
Identities = 47/242 (19%), Positives = 107/242 (44%), Gaps = 23/242 (9%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSS 278
++K++ R+ DR +++++KDR +K R +H++ + + +
Sbjct: 66 REKRQTERETDRKRERRREKDRHRK-----RDRHRERQRDREKERERQTDRERDRQREKE 120
Query: 279 ESESNNKEKKIQRK-KRKKNKCSGHNNSDSEEKDKSKKRKLH---EELSSSHHNREKAKE 334
+ +E++ +R+ +R +++ + ++D K+R+ E + NR+K +E
Sbjct: 121 RNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERE 180
Query: 335 KPRFLKHESSREDSKWSHSDSDKKSRTH-KHSPEKRGSERKEGSSRSHGREERSRRSRSR 393
+ E +R++ + +K+++T +HS R ER+ + R+ ++ R R R
Sbjct: 181 R------EKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 394 SPGSYKQRETRKRAQRNPGEEQSRRND-----SRSHGTDLYRGEKMYREHPGGTHTKVTQ 448
+ ++RE K+A+R E+ D R D R +K + T+
Sbjct: 235 QRKTERERE--KQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 449 RE 450
R+
Sbjct: 293 RD 294
Score = 62.8 bits (151), Expect = 6e-10
Identities = 44/241 (18%), Positives = 98/241 (40%), Gaps = 23/241 (9%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDR---------KKKKFQKSRSKHKKHKSSSSSSSSSSSSS 269
+Q++K + DR ++ ++++R +K++ + R + +K + + +S
Sbjct: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS 252
Query: 270 STETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNR 329
ET ++++ R+++++ + + E+D+ +RK + R
Sbjct: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ-----RER 307
Query: 330 EKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRR 389
E+ +E+ R + E RE + ++++ + KR +E +R GRE R +
Sbjct: 308 ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
Query: 390 SRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQR 449
R +RE + R E+ R R R + ++ G T+ QR
Sbjct: 368 ER--------ERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE-KQR 418
Query: 450 E 450
E
Sbjct: 419 E 419
Score = 62.0 bits (149), Expect = 1e-09
Identities = 52/252 (20%), Positives = 104/252 (41%), Gaps = 34/252 (13%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDR-------------------KKKKFQKSRSKHKKHKSSS 259
K +Q+ + + EK+ K +DR +K++ + R + +K +
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242
Query: 260 SSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLH 319
+ +S ET ++++ R+++++ + + E+D+ +RK
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 320 EELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSR 379
+ RE+ +E+ R + E RE + ++++ + KR +E +R
Sbjct: 303 RQ-----RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR 357
Query: 380 SHGRE-----ERSR-RSRSRSPGSYKQRETRKR-AQRNPGEEQSRRNDSRSHG---TDLY 429
GRE ER R R R R S ++RE R+R R+ +E+ R+ + G T+
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Query: 430 RGEKMYREHPGG 441
R + RE G
Sbjct: 418 REREKDRESERG 429
Score = 59.7 bits (143), Expect = 5e-09
Identities = 50/246 (20%), Positives = 111/246 (45%), Gaps = 20/246 (8%)
Query: 203 EGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKF-------QKSRSKHKKH 255
E + D E E + ++ ++ ++ +R ++++++ +R+ ++ Q+ R + +
Sbjct: 96 ERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDA 155
Query: 256 KSSSSSSSSSSSSSSTETS-ESSSESESNNKEKK-IQRKKRKKNKCSGHNNSDSEEKDKS 313
+ + TE + + E E N +E++ +R++ K+NK ++ E+++
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE 215
Query: 314 KKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSER 373
++ + E R+ +E+ R K E RE ++ ++ S ++R ER
Sbjct: 216 RETETETE-----RKRQTDRERDRQRKTERERE----KQAERERASERETERDKERERER 266
Query: 374 KEGSSRSHGREERSRRS-RSRSPGSYKQRET-RKRAQRNPGEEQSRRNDSRSHGTDLYRG 431
R ++ER R++ R R + + RET RKR ++ E + RN R + R
Sbjct: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 432 EKMYRE 437
+ RE
Sbjct: 327 RERQRE 332
Score = 59.3 bits (142), Expect = 7e-09
Identities = 33/196 (16%), Positives = 87/196 (44%), Gaps = 3/196 (1%)
Query: 226 RKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNK 285
R+ D ++++++D +K++ +++ + ++ + + E E + E NK
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 286 EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR 345
+ ++ ++ + +++E K ++ + + + + REK E+ R + E+ R
Sbjct: 201 TEDRHSERGRERERERETETETERKRQTDRER--DRQRKTEREREKQAERERASERETER 258
Query: 346 EDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRK 405
+ + D D + R + +R ++RK RE +R R R ++R ++
Sbjct: 259 DKERERERDRD-RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 406 RAQRNPGEEQSRRNDS 421
+R E+ R+ ++
Sbjct: 318 ERERERERERERQRET 333
Score = 55.1 bits (131), Expect = 1e-07
Identities = 41/219 (18%), Positives = 92/219 (42%), Gaps = 16/219 (7%)
Query: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETS-ESSSESESNNKEK 287
DR ++K+++R+++K Q R +K + E + E E +
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 288 KIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSRED 347
+ +++++++N+ E ++ + R+ + RE+ ++ + + ++ RE
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQ-----TDGQRERERQRDAEKERERQTDRER 167
Query: 348 SKWSHSDSDKKSRTHKHSPEKRGSER-KEGSSRSHGREERSRRSRSRSPGSYKQRETRKR 406
+ + + K+ K+ E+R ER +E +++ R R R R +RET
Sbjct: 168 QRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER------ERETETE 221
Query: 407 AQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTK 445
+R + Q+ R R T+ R ++ RE T+
Sbjct: 222 TER---KRQTDRERDRQRKTEREREKQAERERASERETE 257
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 69.3 bits (168), Expect = 7e-12
Identities = 99/420 (23%), Positives = 157/420 (37%), Gaps = 56/420 (13%)
Query: 60 GDERVKNGLNFMYEAPPGAKKENKEKEETEGETE-------YKFEWQKGAPREKYAKDDM 112
G R K + E P +++EN E E +++ Y E R+K ++ M
Sbjct: 119 GRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELM 178
Query: 113 NIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIA 172
+ + ++ R IK V + P L +S P S P +
Sbjct: 179 KLEQE--NMEKREEIIIKKEVSPEVVRSKLSPSPSLR--KSSKSPKRKSSPKSSSASK-K 233
Query: 173 EMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLE 232
+ + S + RN N ++ + P E + +L K K+K K DR+E
Sbjct: 234 DRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDI-ALGKKYKEKYKVK-DRIE 291
Query: 233 KKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRK 292
+K + + + F++ R K K +S+S + S SS S SS S + R+
Sbjct: 292 EKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRR 351
Query: 293 K----------------RKKNKCSGHNNSDSEEKD---------KSKKRKLHEELSSSHH 327
K R + H+ S + K + K R HE S SH
Sbjct: 352 KRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHD 411
Query: 328 NREKAKEKPRFL--KHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREE 385
R + +E R + + SRE+ ++ S SR H+ E R +G R R+
Sbjct: 412 RRHERREDTRGKRDREKDSREEREYEQDQS--SSRDHRDDREPR-----DGRDRRDARDT 464
Query: 386 RSRRSRSRSPGSYKQRETR-----KRAQRNPGEEQSRR--NDSRS-HGTDLYRGEKMYRE 437
R RR S RE R + R+P + +S R +D R G D +R E Y E
Sbjct: 465 RDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPE 524
Score = 62.0 bits (149), Expect = 1e-09
Identities = 44/204 (21%), Positives = 91/204 (44%), Gaps = 12/204 (5%)
Query: 226 RKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNK 285
R++DR++ ++ ++ R++ + ++ R + ++ + E + K
Sbjct: 663 RRVDRVDDRRDERARERDR-ERERDRERERERERERDREREKERELERERAREREREREK 721
Query: 286 EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR 345
E+ ++R +++ E+D+ K+R+ E RE+ +E+ R + E +R
Sbjct: 722 ERD---RERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERAR 778
Query: 346 EDSK--WSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRET 403
E K D + K + EKR R++ + R G +ER + R R+ GS R++
Sbjct: 779 ERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRD-GHDERKSKKRYRNEGSPSPRQS 837
Query: 404 RKRAQRNPGEEQSRRNDSRSHGTD 427
KR + E S +D+ + G D
Sbjct: 838 PKRRR-----EHSPDSDAYNSGDD 856
Score = 54.7 bits (130), Expect = 2e-07
Identities = 38/198 (19%), Positives = 86/198 (43%), Gaps = 6/198 (3%)
Query: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKK 288
DR ++ + + F++ R + + + SS + E + +E++
Sbjct: 606 DRYPERDNRDQARDSSFER-RHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664
Query: 289 IQRKKRKKNKCSGHNNSDSE---EKDKSKKRKLHEELSSSHH-NREKAKEKPRFLKHESS 344
+ R ++++ + + + E E+++ ++R+ E RE+A+E+ R + E
Sbjct: 665 VDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERD 724
Query: 345 REDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETR 404
RE + D +++ + ++R ER+E R RE R R R ++R+
Sbjct: 725 RERDRDRDHDRERERERERDREKEREREREE-RERERERERERERERERERERARERDKE 783
Query: 405 KRAQRNPGEEQSRRNDSR 422
+ QR+ ++ R+D R
Sbjct: 784 RERQRDWEDKDKGRDDRR 801
Score = 53.9 bits (128), Expect = 3e-07
Identities = 52/234 (22%), Positives = 102/234 (43%), Gaps = 32/234 (13%)
Query: 203 EGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSS 262
E E D E E +++++ R+ +R +++++++R++++ +++R + K+ +
Sbjct: 740 ERERDREKE-------REREREERERERERERERERERERER-ERARERDKERERQRDWE 791
Query: 263 SSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEEL 322
+ N ++ +RK +K+ + N + K+R+ H
Sbjct: 792 DKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYR----NEGSPSPRQSPKRRREHSPD 847
Query: 323 SSSHHNREKAKEKPRFLKHESSREDSKW---SHSDSDKKSRTHKHSPEKRGSERKEGSSR 379
S ++++ + EK R L ++S+ SH D++ R + E R ERKE S R
Sbjct: 848 SDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKE---EDRKPERKESSRR 904
Query: 380 SHGREERSRRSRSRSPGSYKQRE-------TRKRAQRNPGEEQS--RRNDSRSH 424
+E + + S KQRE +R RAQ G QS R R+H
Sbjct: 905 YEEQELKEKVS-----SVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAH 953
Score = 53.5 bits (127), Expect = 4e-07
Identities = 48/267 (17%), Positives = 102/267 (38%), Gaps = 23/267 (8%)
Query: 187 GRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQ 246
GRN + S+ + +E + E + ++ R R+ + +K R + Q
Sbjct: 530 GRNHLREESSRTEIRNESRNESRSEI-------RNDRMGRSRGRVPELPEKGSRGSRGSQ 582
Query: 247 -KSRSKHKKHKSSSSSSSS-------SSSSSSTETSESSSESESNNKEKKIQRKK--RKK 296
S S + + S + SS + + +SS E ++++ R++ R
Sbjct: 583 IDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPS 642
Query: 297 NKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSD 356
+ +D E+D+ ++ + + + R + +++ R E RE + + +
Sbjct: 643 SPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRERE 702
Query: 357 KKSRTHKHSPEKRGSERKE------GSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRN 410
K+ + +R ER++ R H RE R R R ++RE R+R +
Sbjct: 703 KERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERER 762
Query: 411 PGEEQSRRNDSRSHGTDLYRGEKMYRE 437
E + R R + + + R+
Sbjct: 763 ERERERERERERERARERDKERERQRD 789
Score = 53.5 bits (127), Expect = 4e-07
Identities = 47/228 (20%), Positives = 96/228 (42%), Gaps = 18/228 (7%)
Query: 203 EGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSS 262
E E D E E + ++++ R+L+R ++++++R+K++ + R + + H
Sbjct: 682 ERERDRERERERERERDREREKERELERERAREREREREKER-DRERDRDRDHDRERERE 740
Query: 263 SSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNS-----DSEEKDKSK--K 315
E E E + ++ + ++R++ + + D E+KDK + +
Sbjct: 741 RERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDR 800
Query: 316 RKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKE 375
R+ EE+ + R+ E + R ++ S S R +HSP+ +
Sbjct: 801 REKREEIREDRNPRDGHDE-----RKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGD 855
Query: 376 GSSRSH---GREERSRRSRSRSPGSY-KQRETR-KRAQRNPGEEQSRR 418
+ H + R + SRS SP + R+ R K R P ++S R
Sbjct: 856 DKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSR 903
Score = 47.0 bits (110), Expect = 4e-05
Identities = 42/207 (20%), Positives = 74/207 (35%), Gaps = 7/207 (3%)
Query: 232 EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQR 291
E+ + DR+ ++ + +R K + K S SS+ E + +
Sbjct: 404 ERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARD 463
Query: 292 KKRKKNKCSGHNNSDSEE-KDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKW 350
+ ++ + DS E +D S+ K + S R+ + R + +ED+
Sbjct: 464 TRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYP 523
Query: 351 SHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRN 410
S S ++ + S SRS R +R RSR R P E ++ R
Sbjct: 524 EESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVP------ELPEKGSRG 577
Query: 411 PGEEQSRRNDSRSHGTDLYRGEKMYRE 437
Q + S S+ D + Y E
Sbjct: 578 SRGSQIDSHSSNSNYHDSWETRSSYPE 604
Score = 46.2 bits (108), Expect = 6e-05
Identities = 58/292 (19%), Positives = 108/292 (36%), Gaps = 27/292 (9%)
Query: 173 EMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVE--FLKSLTTKQKQKLLRKLDR 230
EMR+ K + R+ + + +Y EG + E + + + + L + R
Sbjct: 481 EMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSR 540
Query: 231 LEKKKKKKDRKKKKFQKSRSKHKKHK--------SSSSSSSSSSSSSSTETSESSSESES 282
E + + ++ + + + R + + S S S S SS S E+ S
Sbjct: 541 TEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRS 600
Query: 283 NNKEKKIQRKKRKKNKCSGHNNSDSE---EKDKSKKRKLHEELSSSHHNREKAKEKPRFL 339
+ E+ R + N+ ++S E+D+ R+ + SS ++ + E L
Sbjct: 601 SYPER--DRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDE----L 654
Query: 340 KHESSREDSKWSHSDSDKKSRTHKHSPEK-RGSERKEGSSRSHGREERSRRSRSRSPGSY 398
+ + RE+ + D + R + E+ R ER+ R RE R R
Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARE 714
Query: 399 KQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPGGTHTKVTQRE 450
++RE K R R+ R H + R + RE + +RE
Sbjct: 715 REREREKERDRE-------RDRDRDHDRERERERERDREKEREREREERERE 759
Score = 41.6 bits (96), Expect = 0.001
Identities = 54/253 (21%), Positives = 99/253 (39%), Gaps = 39/253 (15%)
Query: 200 VASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSS 259
V G D E +T ++K ++ D+L K+ + R + H S
Sbjct: 1227 VLHSGSRDREKTKSLEITGERKSRI----DQL-----KRGEPSRSTSSDRQDSRSHSSRR 1277
Query: 260 SSSSSS----SSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKK 315
SS S S S S ++ + E + +++ +R++R + ++D + +
Sbjct: 1278 SSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDR 1337
Query: 316 RKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDK-KSRTHKHSPEKRGSERK 374
+L E RE+ ++K R L E R S D D+ + RT + S + K
Sbjct: 1338 DRLRE------RERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESS---QIESVK 1388
Query: 375 EGSSRSHGREERSRRSRSRSP------------GSYKQRETRKRAQR----NPGEEQSRR 418
++ G ER S SR GS + E +++R G+++S+
Sbjct: 1389 RCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKL 1448
Query: 419 NDSRSHGTDLYRG 431
+D+ S G+ G
Sbjct: 1449 DDAHSLGSGAGEG 1461
Score = 41.2 bits (95), Expect = 0.002
Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 9/189 (4%)
Query: 197 QEYVASEGEEDPEVEFLKSLTTKQKQKL-LRKLDRLEKKKKKKDRKKKKFQKSRSKHKKH 255
+E V+S ++ + E L+S + + + + + E + D KKK + + KK
Sbjct: 911 KEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKK 970
Query: 256 KSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNN-SDSEEKDKSK 314
K + +++E + S + K+K I++K++K G ++ SD E +SK
Sbjct: 971 KEDDVGIERGNIETTSEDGQVFSPKKGQ-KKKSIEKKRKK---SKGDSDISDEEAAQQSK 1026
Query: 315 KRK--LHEELSSSHHNREKAKEKPRFLKHESSREDSKWSH-SDSDKKSRTHKHSPEKRGS 371
K++ +++ E K L+ +ED+ +S SD D RT E +
Sbjct: 1027 KKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTAT 1086
Query: 372 ERKEGSSRS 380
GS+ S
Sbjct: 1087 ATTPGSTPS 1095
Score = 41.2 bits (95), Expect = 0.002
Identities = 46/178 (25%), Positives = 69/178 (38%), Gaps = 31/178 (17%)
Query: 250 SKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEE 309
++H+K SSS S+ S+ + S SN+ S H + D +
Sbjct: 1178 AQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSND---------------SAHRSGDDQS 1222
Query: 310 KDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKR 369
+KR LH S +REK K L+ R+ S D K+ + + R
Sbjct: 1223 ---GRKRVLH----SGSRDREKTKS----LEITGERK----SRIDQLKRGEPSRSTSSDR 1267
Query: 370 GSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTD 427
R S RS +R SRS S S + + R R + + E+ RR D+R D
Sbjct: 1268 QDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERR-DTRQREWD 1324
Score = 38.5 bits (88), Expect = 0.013
Identities = 42/196 (21%), Positives = 78/196 (39%), Gaps = 16/196 (8%)
Query: 226 RKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSS--------SSSSTETSESS 277
RK R +K + + + R + +SSS S+ S+ S S +++ S
Sbjct: 1158 RKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRS 1217
Query: 278 SESESNNK----EKKIQRKKRKKNKCSGHNNSDSEE---KDKSKKRKLHEELSSSHHNRE 330
+ +S K R+K K + +G S ++ + S+ + S SH +R
Sbjct: 1218 GDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRR 1277
Query: 331 KAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRS 390
+ E R + S DS+ + D+ + E+R + ++E R ++ R
Sbjct: 1278 SSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREW-DRDADKDWPRNRD 1336
Query: 391 RSRSPGSYKQRETRKR 406
R R ++RE KR
Sbjct: 1337 RDRLRERERERERDKR 1352
Score = 37.7 bits (86), Expect = 0.021
Identities = 51/246 (20%), Positives = 91/246 (36%), Gaps = 27/246 (10%)
Query: 218 TKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESS 277
T++ +RK + ++K+D K K R+ + ++ ++ S + +
Sbjct: 105 TEESSSPVRKESSRGRHREKEDIK---ITKERTPESEEENVEWETNRDDSDNGDINYDYV 161
Query: 278 SESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPR 337
E K +KIQR+ K + + + K + + +LS S R+ +K R
Sbjct: 162 HELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKR 221
Query: 338 FLKHESS---REDSKWSHSDS--------DKKSRTHKHSPEKR------------GSERK 374
+SS ++D K S S K +++ K P G + K
Sbjct: 222 KSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYK 281
Query: 375 EGSSRSHGREERSRRSRSRSPGSYKQRETR-KRAQRNPGEEQSRRNDSRSHGTDLYRGEK 433
E EE++R + R +QRE R K +P + SR H + G
Sbjct: 282 EKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSS 341
Query: 434 MYREHP 439
+ R P
Sbjct: 342 IQRHSP 347
Score = 37.7 bits (86), Expect = 0.021
Identities = 32/154 (20%), Positives = 58/154 (37%), Gaps = 8/154 (5%)
Query: 247 KSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSD 306
+S S H+S S S ++S E+K + + K+ + S +SD
Sbjct: 1207 RSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSD 1266
Query: 307 SEEKDKSKKRKLHEE-------LSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKS 359
++ R+ E S S +R++ +E+ R+ +H+ RE + +
Sbjct: 1267 RQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY-EHDRERERERRDTRQREWDR 1325
Query: 360 RTHKHSPEKRGSERKEGSSRSHGREERSRRSRSR 393
K P R +R R R++R R R
Sbjct: 1326 DADKDWPRNRDRDRLRERERERERDKRRDLDRER 1359
Score = 36.6 bits (83), Expect = 0.048
Identities = 47/230 (20%), Positives = 96/230 (41%), Gaps = 25/230 (10%)
Query: 188 RNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQK 247
R+L+ + +++ EED + E +S ++Q+L K+ ++K++++ + + +
Sbjct: 874 RSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMR 933
Query: 248 SRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEK-KIQRKKRKKNKCSGHNNSD 306
++ H+S E E+S + NK+K KIQ+K KK K ++
Sbjct: 934 AQDIIGHHQS--------------EDRETSDRAHDENKKKAKIQKKPIKKKK---EDDVG 976
Query: 307 SEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDS---DKKSRTHK 363
E + + + S ++K+ EK K + S+ DS S ++ KK R +
Sbjct: 977 IERGNIETTSEDGQVFSPKKGQKKKSIEK----KRKKSKGDSDISDEEAAQQSKKKRGPR 1032
Query: 364 HSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGE 413
P E E + +G E S++ + + + R + E
Sbjct: 1033 TPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAE 1082
Score = 32.0 bits (71), Expect = 1.2
Identities = 34/179 (18%), Positives = 67/179 (37%), Gaps = 28/179 (15%)
Query: 246 QKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCS----- 300
Q+SRS H + E ESS E ++K+ +++ +
Sbjct: 871 QESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESS 930
Query: 301 --------GHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSH 352
GH+ S+ D+ + H+E N++KAK + + +K + +D
Sbjct: 931 RMRAQDIIGHHQSE----DRETSDRAHDE------NKKKAKIQKKPIK-KKKEDDVGIER 979
Query: 353 SDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNP 411
+ + S + K+G ++K + ++S+ S Q+ +KR R P
Sbjct: 980 GNIETTSEDGQVFSPKKGQKKKS----IEKKRKKSKGDSDISDEEAAQQSKKKRGPRTP 1034
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 68.9 bits (167), Expect = 9e-12
Identities = 75/261 (28%), Positives = 101/261 (38%), Gaps = 80/261 (30%)
Query: 232 EKKKKKKDRKKKKFQKSRSKHK-KHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQ 290
E+ K KKKK K SKHK KHK+ +T E SS++ES K KK +
Sbjct: 667 ERSGKSHRHKKKKKHKKSSKHKRKHKA--------------DTEEKSSKAESGEKSKKRK 712
Query: 291 RKKRKKNKCSGHNNSDSEEK-------------------DKSKKRKLHEELSSS------ 325
++KRKKNK S +S+ K D S++R L E SS
Sbjct: 713 KRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEG 772
Query: 326 --------HHNREKAKEKP--RFLKHESSREDSKWSH----------SDSDKKSRTHKHS 365
H R+ E P + ++ S+ SH SD R H+ S
Sbjct: 773 GGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKS 832
Query: 366 P---------EKRGSERKEGSSRSHGREERSRRSRSRSPGS----------YKQRETRKR 406
P E GSE SRS GR S RS RS S Y ++ +
Sbjct: 833 PSQYSEEEEEEDSGSEHSRSRSRS-GRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSD 891
Query: 407 AQRNPGEEQSRRNDSRSHGTD 427
+ ++SRR+ RSH +D
Sbjct: 892 DSYSDYSDRSRRHSKRSHDSD 912
Score = 62.0 bits (149), Expect = 1e-09
Identities = 62/260 (23%), Positives = 100/260 (38%), Gaps = 41/260 (15%)
Query: 188 RNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQK 247
R+ ++ SQ E +D L + Q + + D + + + R ++
Sbjct: 803 RSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSS 862
Query: 248 SRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDS 307
RS + + SSS +SS S S + SD
Sbjct: 863 HRSSRRSYSSSSDASSDQSCYSRQ------------------------------RSYSDD 892
Query: 308 EEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPE 367
D S + + H + S + + A K R +H+ S D +S S S +SR+ H+ E
Sbjct: 893 SYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRE 952
Query: 368 K-RGSERKEGSSRSHGREERSRRS-------RSRSPGSYKQRETRKRAQRNPGEEQSRRN 419
+ R R SS S R +R RS RSRS + R TR +QR+ ++S +
Sbjct: 953 RSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGH 1012
Query: 420 DS---RSHGTDLYRGEKMYR 436
+S R G + K+YR
Sbjct: 1013 ESPEERHSGRRDFIRSKIYR 1032
Score = 59.3 bits (142), Expect = 7e-09
Identities = 57/207 (27%), Positives = 81/207 (39%), Gaps = 17/207 (8%)
Query: 246 QKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNS 305
+ SRS H+ SS S +SS S SE +E R +++ SG +S
Sbjct: 803 RSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSR-SGRRHS 861
Query: 306 DSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKH-ESSREDSKWSHS--DSDKKSRTH 362
+S S ++R+++ + + + SR SK SH DSD S H
Sbjct: 862 SHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKH 921
Query: 363 KHSPEKRGSERKEGS---------SRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGE 413
+ K S + S SRSH RE RSR RS S R KR R+
Sbjct: 922 RSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERS--RSRGRSRSSSCSRSRSKRRSRSTTA 979
Query: 414 EQSRRNDSRSHGTDLYRGEKMYREHPG 440
+R SRS+ D R + + G
Sbjct: 980 HSWQR--SRSYSRDRSRSTRSPSQRSG 1004
Score = 58.5 bits (140), Expect = 1e-08
Identities = 66/276 (23%), Positives = 114/276 (41%), Gaps = 37/276 (13%)
Query: 152 NASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDPEVE 211
+ASS PS + E E S + R+ GR +++ S+ +S + +
Sbjct: 822 DASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQS 881
Query: 212 FLKSLTTKQKQKLLRKLDRLEKKKKKK-DRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSS 270
+ DR + K+ D + S+ + K+HK SSS S S S
Sbjct: 882 CYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCS- 940
Query: 271 TETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNRE 330
+S S S S+ +E+ R + + + CS + +SK+R S +R
Sbjct: 941 ----QSRSRSRSHTRERSRSRGRSRSSSCS---------RSRSKRRSRSTTAHSWQRSRS 987
Query: 331 KAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRS 390
++++ R + S R S+ K+S H+ SPE+R S R++ RS+
Sbjct: 988 YSRDRSRSTRSPSQRSGSR-------KRSWGHE-SPEERHSGRRDFI--------RSKIY 1031
Query: 391 RSRSPGSYKQRETRKRAQRNPG-EEQSRRNDSRSHG 425
RS+SP + R PG ++ R +DS++ G
Sbjct: 1032 RSQSPHYF-----RSGRGEGPGKKDDGRGDDSKATG 1062
Score = 55.5 bits (132), Expect = 1e-07
Identities = 63/282 (22%), Positives = 105/282 (37%), Gaps = 64/282 (22%)
Query: 218 TKQKQKLLRKLDRLEKKKKKKDRKKKKF-----------------------QKSRSKHKK 254
T++K ++ +K+KK+K +K K ++ R++
Sbjct: 695 TEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDS 754
Query: 255 HKSSSSSSSSSSSSSSTETSESSSESESNNKEK------KIQRKK-RKKNKCSGHN---N 304
+ S + SS SSS+ K K QR+ K++ S H +
Sbjct: 755 QRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPS 814
Query: 305 SDSEEKDKSKKRKLH------------EELSSSHHNREKAKEKPRFLKHESSRE------ 346
S E+ D + +LH EE S S H+R +++ R H SSR
Sbjct: 815 SGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSS 874
Query: 347 ---------DSKWSHSD---SDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRS 394
+ S+SD SD R+ +HS S+ + +S H R +R + S S
Sbjct: 875 DASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKH-RSKRHKYSSSDD 933
Query: 395 PGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYR 436
S ++R R++ + E R SRS R ++ R
Sbjct: 934 DYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSR 975
Score = 51.2 bits (121), Expect = 2e-06
Identities = 96/420 (22%), Positives = 158/420 (37%), Gaps = 58/420 (13%)
Query: 74 APPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIK-CH 132
A GA+K E E ET + G+ E ++ DQ + V + C
Sbjct: 450 ASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCE 509
Query: 133 KWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTA 192
N+ +E L +G + P +GP ++++ ++ +L T
Sbjct: 510 S----NSSKETSLATPAGKESQEGPKHPTGPFF---PVLSKDESTALQWPSELL--IFTK 560
Query: 193 NDPSQEYVASEGEEDPEVEFLKSLTTKQKQKL----------LRKLDRLEKKKKKKDRKK 242
+PS Y + D ++ K TK +K L+ LD E K K+ +
Sbjct: 561 AEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGE 620
Query: 243 KKFQKSRSKHKKHKSSSSSSS------SSSSSSSTETSESSSESESNNKEKKIQRKKRKK 296
K + S + S S+ S S S TE + S S+ K + KK+KK
Sbjct: 621 KIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKK 680
Query: 297 NKCSGHNN----SDSEEK-------DKSKKRKLH---EELSSSHHNREKA-KEKPRFLKH 341
+K S + +D+EEK +KSKKRK + SS+ + E+ K +P
Sbjct: 681 HKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGS 740
Query: 342 ESSREDSKWSHSDSDKKSRTHKHSPEKRGSERK--EGSSRSHGREERSRRSRSR-SPGSY 398
+ + + DS ++S P + GS K EG S ++ R+ + P S
Sbjct: 741 PAPPRRRRRAQDDSQRRS-----LPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSC 795
Query: 399 KQRETRKRAQRNPGEEQSRRNDSRSHGTDLYR---------GEKMYREHPGGTHTKVTQR 449
++R KR+ R+ Q D S +R E+ E G H++ R
Sbjct: 796 QRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSR 855
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 68.6 bits (166), Expect = 1e-11
Identities = 57/231 (24%), Positives = 110/231 (47%), Gaps = 27/231 (11%)
Query: 205 EEDPEVEFLKSLTTKQKQKLLR-KLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSS 263
E D +V K T + +L K + EK+K+ + R S S + + S+SS+ S
Sbjct: 473 EADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVS 532
Query: 264 SSSSSSSTETSESSSESESNNKEKKIQRK-----KRKKNKCSGHNNSDSEEKDKSKKRKL 318
SSS SSS+ +S +SS S S ++K+ R K ++++ ++ E ++++ K+
Sbjct: 533 SSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARV-KI 591
Query: 319 HEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSR------------------ 360
+ S+ ++ E+ + + R E R S+ +++ SR
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSG 651
Query: 361 -THKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRN 410
+HKH E + ERK+ SRS + +R ++ + R K++E +KR +++
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDK-DRKKKDKEREREQDKRKEKQKREEKD 701
Score = 64.7 bits (156), Expect = 2e-10
Identities = 85/386 (22%), Positives = 150/386 (38%), Gaps = 42/386 (10%)
Query: 29 EQKISYDKKKQEELMQ--QYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGAKKENKEKE 86
EQ++ +DK+ +EE Q + KE + ++ +N L+ + EA EK+
Sbjct: 432 EQQLLHDKQMEEEKQQTERVTKEMNEFIHK-------EQNSLSLL-EAREADGDVVNEKK 483
Query: 87 ETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLF 146
T ET E +K +EK + G N R T
Sbjct: 484 RTPNETTSVLEPKK-EHKEKEKQGRSRSGSSSSGSSSSNSR-----------TSSTSSTV 531
Query: 147 GLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALK-RNVLGRNLTANDPSQEYVASEGE 205
S ++SS + S S P R+ +K R R+ + + A
Sbjct: 532 SSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKI 591
Query: 206 EDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKK----HKSSSSS 261
D S+ ++++ +R + + +DR+ + +SRS+ ++ + + S
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSG 651
Query: 262 SSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKD---KSKKRKL 318
+S + E S S +K++K + K+R++ + EEKD S+ +L
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
Query: 319 HEELSSSHHNREKAKEKPRFLKHESSREDSKWS-------HSDSDKKSRTHKHSP----E 367
+ S + ++H+S R+DSK S HS SD R+ SP E
Sbjct: 712 KRKRESERTFSRSGSISVKIIRHDS-RQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKE 770
Query: 368 KRGSERKEGSSRSHGREERSRRSRSR 393
K+ + K SRS + +RS + SR
Sbjct: 771 KKAKKPKHSRSRSVEKSQRSGKKASR 796
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/223 (27%), Positives = 101/223 (45%), Gaps = 41/223 (18%)
Query: 236 KKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRK 295
KK+ ++K+K +SRS SSSS+S +SS+SS+ +S SS S S+ + KRK
Sbjct: 496 KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
Query: 296 KNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDS 355
K + + + +S+ ++ S NR + K + D + S+ +S
Sbjct: 556 KRHSRSRSPTIKARRSRSRSYSRRIKIES---NRARVKIR-----------DRRRSNRNS 601
Query: 356 DKKSRTHKHSPEKRGSERKEGSSRSHGREERSRR-SRSRS-------------------- 394
++ R SP + ER+ SRS R+ R+ R SRSRS
Sbjct: 602 IERERRRNRSPSR---ERRR--SRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKH 656
Query: 395 PGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
G K++E +K R+ +++ +++ R D R EK RE
Sbjct: 657 KGEAKEQERKKERSRSIDKDRKKKDKEREREQD-KRKEKQKRE 698
Score = 60.8 bits (146), Expect = 2e-09
Identities = 44/200 (22%), Positives = 86/200 (43%), Gaps = 18/200 (9%)
Query: 232 EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQR 291
E+++ + ++++ +SRS+ ++ +S S S + S S + E K Q
Sbjct: 605 ERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQE 664
Query: 292 KKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWS 351
+K+++ S DK +K+K E +EK K + + K S + K
Sbjct: 665 RKKER----------SRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRK 714
Query: 352 HSDSDKKSRTH-------KHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETR 404
SR+ +H + + S+ H + S RS S SPGS K+++ +
Sbjct: 715 RESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAK 774
Query: 405 K-RAQRNPGEEQSRRNDSRS 423
K + R+ E+S+R+ ++
Sbjct: 775 KPKHSRSRSVEKSQRSGKKA 794
Score = 53.5 bits (127), Expect = 4e-07
Identities = 87/434 (20%), Positives = 169/434 (38%), Gaps = 73/434 (16%)
Query: 17 ASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPP 76
A K W+ E +++KQ++L ++ +++Q S +
Sbjct: 226 AVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLS--------------------- 264
Query: 77 GAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGH 136
KKE K E+ EG + + ++ +D N+ G R+ + +
Sbjct: 265 --KKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSD 322
Query: 137 ---VNTDRECPLFGLSGINASSVPTDGSGPSMH-------------PSELIAEMRNSGFA 180
++E + L+ + + + D + ++ P++ +A+ +S A
Sbjct: 323 PEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQ--SSALA 380
Query: 181 LKRNVLGRNLTANDPSQEYVASEGEE--DPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKK 238
+ G + S++ + G E D + E L+ ++++ RK EK+++
Sbjct: 381 SLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRK----EKEQQLL 436
Query: 239 DRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNK 298
K+ + +K +++ + + +S S E E+ + + KKR N+
Sbjct: 437 HDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV--------VNEKKRTPNE 488
Query: 299 CSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKK 358
+ E K+K K+ + SSS + ++ +S S S+S S
Sbjct: 489 TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTS------STSSTVSSSSYSSSSGS 542
Query: 359 SRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRET---------RKRAQR 409
SRT S + RK+ SRS ++RRSRSRS + E+ R+R+ R
Sbjct: 543 SRTSSRSSSPK---RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNR 599
Query: 410 NPGEEQSRRNDSRS 423
N E + RRN S S
Sbjct: 600 NSIERERRRNRSPS 613
Score = 53.1 bits (126), Expect = 5e-07
Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 10/166 (6%)
Query: 189 NLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQ-K 247
NL+ N S ++ E++ + E +S+ +K+K + +K+K+K+ R++K F+
Sbjct: 648 NLSGN--SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
Query: 248 SRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDS 307
S+ K K S + S S S S + S +S K KK + SG ++S+S
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTK-DSKKHSGSDSSGRSSSES 764
Query: 308 EEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHS 353
K KK K H+R ++ EK + ++SR+ S S
Sbjct: 765 PGSSKEKKAK------KPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
Score = 48.9 bits (115), Expect = 9e-06
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 9/151 (5%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSS 278
++K++ R +D+ ++KKK K+R++++ K + K K+ + SS SE +
Sbjct: 664 ERKKERSRSIDK-DRKKKDKEREREQ-DKRKEKQKREEKDFKFSSQDDRLKRKRESERTF 721
Query: 279 ESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRF 338
+ K I+ R+ +K S +S S R E SS +EK +KP
Sbjct: 722 SRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSS---KEKKAKKP-- 776
Query: 339 LKHESSREDSKWSHSDSDKKSRTHKHSPEKR 369
KH SR K S K SR HK R
Sbjct: 777 -KHSRSRSVEK-SQRSGKKASRKHKSKSRSR 805
Score = 32.7 bits (73), Expect = 0.69
Identities = 23/116 (19%), Positives = 52/116 (44%), Gaps = 2/116 (1%)
Query: 205 EEDPEVEFLKSLTTKQK-QKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSS 263
+E P+++ +K T ++ L K++R ++KK +K+R +++ + K KK +
Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGD 278
Query: 264 SSSSSSSTETSESSSESESNNKEKKIQRK-KRKKNKCSGHNNSDSEEKDKSKKRKL 318
++ E ++ N E K R + +SD E ++ K+ ++
Sbjct: 279 GPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQM 334
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 68.6 bits (166), Expect = 1e-11
Identities = 57/231 (24%), Positives = 110/231 (47%), Gaps = 27/231 (11%)
Query: 205 EEDPEVEFLKSLTTKQKQKLLR-KLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSS 263
E D +V K T + +L K + EK+K+ + R S S + + S+SS+ S
Sbjct: 473 EADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVS 532
Query: 264 SSSSSSSTETSESSSESESNNKEKKIQRK-----KRKKNKCSGHNNSDSEEKDKSKKRKL 318
SSS SSS+ +S +SS S S ++K+ R K ++++ ++ E ++++ K+
Sbjct: 533 SSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARV-KI 591
Query: 319 HEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSR------------------ 360
+ S+ ++ E+ + + R E R S+ +++ SR
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSG 651
Query: 361 -THKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRN 410
+HKH E + ERK+ SRS + +R ++ + R K++E +KR +++
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDK-DRKKKDKEREREQDKRKEKQKREEKD 701
Score = 64.7 bits (156), Expect = 2e-10
Identities = 85/386 (22%), Positives = 150/386 (38%), Gaps = 42/386 (10%)
Query: 29 EQKISYDKKKQEELMQ--QYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGAKKENKEKE 86
EQ++ +DK+ +EE Q + KE + ++ +N L+ + EA EK+
Sbjct: 432 EQQLLHDKQMEEEKQQTERVTKEMNEFIHK-------EQNSLSLL-EAREADGDVVNEKK 483
Query: 87 ETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLF 146
T ET E +K +EK + G N R T
Sbjct: 484 RTPNETTSVLEPKK-EHKEKEKQGRSRSGSSSSGSSSSNSR-----------TSSTSSTV 531
Query: 147 GLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALK-RNVLGRNLTANDPSQEYVASEGE 205
S ++SS + S S P R+ +K R R+ + + A
Sbjct: 532 SSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKI 591
Query: 206 EDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKK----HKSSSSS 261
D S+ ++++ +R + + +DR+ + +SRS+ ++ + + S
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSG 651
Query: 262 SSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKD---KSKKRKL 318
+S + E S S +K++K + K+R++ + EEKD S+ +L
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
Query: 319 HEELSSSHHNREKAKEKPRFLKHESSREDSKWS-------HSDSDKKSRTHKHSP----E 367
+ S + ++H+S R+DSK S HS SD R+ SP E
Sbjct: 712 KRKRESERTFSRSGSISVKIIRHDS-RQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKE 770
Query: 368 KRGSERKEGSSRSHGREERSRRSRSR 393
K+ + K SRS + +RS + SR
Sbjct: 771 KKAKKPKHSRSRSVEKSQRSGKKASR 796
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/223 (27%), Positives = 101/223 (45%), Gaps = 41/223 (18%)
Query: 236 KKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRK 295
KK+ ++K+K +SRS SSSS+S +SS+SS+ +S SS S S+ + KRK
Sbjct: 496 KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
Query: 296 KNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDS 355
K + + + +S+ ++ S NR + K + D + S+ +S
Sbjct: 556 KRHSRSRSPTIKARRSRSRSYSRRIKIES---NRARVKIR-----------DRRRSNRNS 601
Query: 356 DKKSRTHKHSPEKRGSERKEGSSRSHGREERSRR-SRSRS-------------------- 394
++ R SP + ER+ SRS R+ R+ R SRSRS
Sbjct: 602 IERERRRNRSPSR---ERRR--SRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKH 656
Query: 395 PGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
G K++E +K R+ +++ +++ R D R EK RE
Sbjct: 657 KGEAKEQERKKERSRSIDKDRKKKDKEREREQD-KRKEKQKRE 698
Score = 60.8 bits (146), Expect = 2e-09
Identities = 44/200 (22%), Positives = 86/200 (43%), Gaps = 18/200 (9%)
Query: 232 EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQR 291
E+++ + ++++ +SRS+ ++ +S S S + S S + E K Q
Sbjct: 605 ERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQE 664
Query: 292 KKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWS 351
+K+++ S DK +K+K E +EK K + + K S + K
Sbjct: 665 RKKER----------SRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRK 714
Query: 352 HSDSDKKSRTH-------KHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETR 404
SR+ +H + + S+ H + S RS S SPGS K+++ +
Sbjct: 715 RESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAK 774
Query: 405 K-RAQRNPGEEQSRRNDSRS 423
K + R+ E+S+R+ ++
Sbjct: 775 KPKHSRSRSVEKSQRSGKKA 794
Score = 53.5 bits (127), Expect = 4e-07
Identities = 87/434 (20%), Positives = 169/434 (38%), Gaps = 73/434 (16%)
Query: 17 ASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPP 76
A K W+ E +++KQ++L ++ +++Q S +
Sbjct: 226 AVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLS--------------------- 264
Query: 77 GAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGH 136
KKE K E+ EG + + ++ +D N+ G R+ + +
Sbjct: 265 --KKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSD 322
Query: 137 ---VNTDRECPLFGLSGINASSVPTDGSGPSMH-------------PSELIAEMRNSGFA 180
++E + L+ + + + D + ++ P++ +A+ +S A
Sbjct: 323 PEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQ--SSALA 380
Query: 181 LKRNVLGRNLTANDPSQEYVASEGEE--DPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKK 238
+ G + S++ + G E D + E L+ ++++ RK EK+++
Sbjct: 381 SLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRK----EKEQQLL 436
Query: 239 DRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNK 298
K+ + +K +++ + + +S S E E+ + + KKR N+
Sbjct: 437 HDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV--------VNEKKRTPNE 488
Query: 299 CSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKK 358
+ E K+K K+ + SSS + ++ +S S S+S S
Sbjct: 489 TTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTS------STSSTVSSSSYSSSSGS 542
Query: 359 SRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRET---------RKRAQR 409
SRT S + RK+ SRS ++RRSRSRS + E+ R+R+ R
Sbjct: 543 SRTSSRSSSPK---RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNR 599
Query: 410 NPGEEQSRRNDSRS 423
N E + RRN S S
Sbjct: 600 NSIERERRRNRSPS 613
Score = 53.1 bits (126), Expect = 5e-07
Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 10/166 (6%)
Query: 189 NLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQ-K 247
NL+ N S ++ E++ + E +S+ +K+K + +K+K+K+ R++K F+
Sbjct: 648 NLSGN--SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
Query: 248 SRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDS 307
S+ K K S + S S S S + S +S K KK + SG ++S+S
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTK-DSKKHSGSDSSGRSSSES 764
Query: 308 EEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHS 353
K KK K H+R ++ EK + ++SR+ S S
Sbjct: 765 PGSSKEKKAK------KPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
Score = 48.9 bits (115), Expect = 9e-06
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 9/151 (5%)
Query: 219 KQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSS 278
++K++ R +D+ ++KKK K+R++++ K + K K+ + SS SE +
Sbjct: 664 ERKKERSRSIDK-DRKKKDKEREREQ-DKRKEKQKREEKDFKFSSQDDRLKRKRESERTF 721
Query: 279 ESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRF 338
+ K I+ R+ +K S +S S R E SS +EK +KP
Sbjct: 722 SRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSS---KEKKAKKP-- 776
Query: 339 LKHESSREDSKWSHSDSDKKSRTHKHSPEKR 369
KH SR K S K SR HK R
Sbjct: 777 -KHSRSRSVEK-SQRSGKKASRKHKSKSRSR 805
Score = 32.7 bits (73), Expect = 0.69
Identities = 23/116 (19%), Positives = 52/116 (44%), Gaps = 2/116 (1%)
Query: 205 EEDPEVEFLKSLTTKQK-QKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSS 263
+E P+++ +K T ++ L K++R ++KK +K+R +++ + K KK +
Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGD 278
Query: 264 SSSSSSSTETSESSSESESNNKEKKIQRK-KRKKNKCSGHNNSDSEEKDKSKKRKL 318
++ E ++ N E K R + +SD E ++ K+ ++
Sbjct: 279 GPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQM 334
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 67.8 bits (164), Expect = 2e-11
Identities = 71/291 (24%), Positives = 117/291 (40%), Gaps = 36/291 (12%)
Query: 170 LIAEMRNSGFALKRNVLGRN-LTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKL 228
++++ + S R + GR + + P + SE ++D E K++ + LR
Sbjct: 318 IVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHW--KEEMQRLRAY 375
Query: 229 DRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKK 288
+K K K SR + S S S + S T+ S + KEKK
Sbjct: 376 RPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKK 435
Query: 289 IQRKKR--KKNKCSGHNNSDSE--------EKDKSKKRKLHEELSSSHHNREKAKEKPRF 338
++ KK+ K+ C H + E KS R++ S +RE++
Sbjct: 436 VKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRM-----KSSCDRERSSRSSSL 490
Query: 339 LKHESSREDSKWSHSDSDKKS----------RTHKHSPE-KRGSERKEGSSRSHGREERS 387
H SS+ D WS SD D +S R+ HS RGS R +S+S
Sbjct: 491 SSHHSSKRD--WSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSR 548
Query: 388 RRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREH 438
+SRS S + RKRA ++P + S+ ++++ T+ R E+
Sbjct: 549 SKSRSSSKSGH-----RKRASKSPRKTASQLSENKPVKTEPLRATMAQNEN 594
Score = 57.4 bits (137), Expect = 3e-08
Identities = 63/252 (25%), Positives = 96/252 (38%), Gaps = 63/252 (25%)
Query: 235 KKKKDRKKKKFQKSRSKHKKHKSSSSSS---------------------------SSSSS 267
++ K R + +K+ HKKH SSS + SS S
Sbjct: 753 RRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSE 812
Query: 268 SSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSE-EKDKSKKRKLHEELSSSH 326
SS + ++S+ E E K+ +++R K+ K G S SE E SKKR L E LS
Sbjct: 813 QSSVQATQSAQEKE---KQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHL 869
Query: 327 HNREKAKEKPRFLKHESSREDSKW-SHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREE 385
N K K K + SKW S S+S++ + + S+++EG + S E
Sbjct: 870 RNGSKPKRK--------NYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESE 921
Query: 386 RSRRSRSRSP--------------GSYKQRETRKRAQRNPGEEQSRRND-----SRSHGT 426
S P G++K + R + G + N+ HG+
Sbjct: 922 VSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGS 981
Query: 427 DLYRGEKMYREH 438
E + REH
Sbjct: 982 K----ENLKREH 989
Score = 54.7 bits (130), Expect = 2e-07
Identities = 39/173 (22%), Positives = 76/173 (43%), Gaps = 3/173 (1%)
Query: 236 KKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRK 295
K DR + +SRS+ + +S S S + S S +S+ + S S S+++ K +
Sbjct: 680 KYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCS 739
Query: 296 KNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDS 355
++ +SD + K + R ++ S SH + EK K+ R+ S S
Sbjct: 740 RSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYS 799
Query: 356 DKKSRTHKHSPEKRGSERKEGSSR---SHGREERSRRSRSRSPGSYKQRETRK 405
+ +S S ++ S + S++ G+ ER+ + ++ G K + R+
Sbjct: 800 ESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERE 852
Score = 54.3 bits (129), Expect = 2e-07
Identities = 59/272 (21%), Positives = 116/272 (42%), Gaps = 31/272 (11%)
Query: 202 SEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSS 261
S E V+ +S K+KQ + + ++K + +++ K + + SK + K + S
Sbjct: 808 SSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSD 867
Query: 262 SSSSSSSSSTETSESSS-ESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKD-----KSKK 315
+ S + S +SESN+ +R K +K H +SD EE + +S+
Sbjct: 868 HLRNGSKPKRKNYAGSKWDSESNS-----ERDVTKNSKNDSHPSSDKEEGEATSDSESEV 922
Query: 316 RKLHEEL-----SSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDK---KSRTHKHSPE 367
++H ++ SS++ + + K +S DS+ S S+S+ K + HKH +
Sbjct: 923 SEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSK 982
Query: 368 --------KRGSERKEG-SSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRR 418
K+ E+ +G + H +R + + P + + E + + +E +
Sbjct: 983 ENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEK 1042
Query: 419 NDSRSHGT---DLYRGEKMYREHPGGTHTKVT 447
S ++ T ++ + EK E G H VT
Sbjct: 1043 KVSENNETIKDNILKTEKSSEEDLSGKHDTVT 1074
Score = 53.9 bits (128), Expect = 3e-07
Identities = 67/249 (26%), Positives = 101/249 (40%), Gaps = 26/249 (10%)
Query: 200 VASEGEEDPEVEFLKSLTTKQKQKLLRKLD-RLEKKKKKKDRKKKKFQKSRSKHKKHKSS 258
V S E ++E LK+ + +R +D + K KD +KK +K SS
Sbjct: 143 VISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKSIKDVFEKKRKKPTHSEGSDSSS 202
Query: 259 SSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCS--------------GHN- 303
+SSSSS SSS S E S + + K++R K+++ + S GH+
Sbjct: 203 NSSSSSESSSES-ELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSE 261
Query: 304 NSDSEEK---DKSKKRK----LHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSD 356
SD+ EK D S KR+ EE+ NR + + E + + SD
Sbjct: 262 RSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSD 321
Query: 357 KKSRTHK--HSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEE 414
+K K + RG+ R RS E S +P +K+ R RA R P E
Sbjct: 322 QKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGE 381
Query: 415 QSRRNDSRS 423
+ + D S
Sbjct: 382 KWSKGDKLS 390
Score = 52.8 bits (125), Expect = 6e-07
Identities = 55/220 (25%), Positives = 90/220 (40%), Gaps = 24/220 (10%)
Query: 209 EVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSS--- 265
EV+ L ++ + Q L R+E K K K R F + R + ++ + SSS
Sbjct: 1247 EVKVLTTVPEMKPQGL-----RIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQ 1301
Query: 266 -------SSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKL 318
S S S S S SE++S ++ + + + S ++ S +S+ R
Sbjct: 1302 TPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGW 1361
Query: 319 HEELSSSHHNREKAKEKPRFLKHE-SSREDSKWSHSDSDKKSRTHKHS---PEKRGSERK 374
+ S R ++ + H SSR S+ S D +SR++ + R R
Sbjct: 1362 Y----SRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRS 1417
Query: 375 EGSSRSHGREERSRRSRS-RSPGSYKQRETRKRAQRNPGE 413
+ S H +RRSRS RS GS + + R+P E
Sbjct: 1418 QRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSE 1457
Score = 48.5 bits (114), Expect = 1e-05
Identities = 46/209 (22%), Positives = 86/209 (41%), Gaps = 13/209 (6%)
Query: 243 KKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGH 302
K+ S S HK+ K+S S S+ S + S+ SSES ++ + + + ++
Sbjct: 656 KETGSSSSYHKREKNSESDQSTYS-----KYSDRSSESSPRSRSRSSRSRSYSRSYTRSR 710
Query: 303 NNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTH 362
+ + S + +S + H S H++ + + R + S K S +H
Sbjct: 711 SLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSH 770
Query: 363 KHSPEKRGSERKEGSSRSHGREERS---RRSRSRSPGSYK--QRETRKRAQRNPGEEQSR 417
K SE+ S GR+ S + S SRS Y ++ +A ++ E++ +
Sbjct: 771 K--KHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQ 828
Query: 418 RNDSRSHG-TDLYRGEKMYREHPGGTHTK 445
R+H + RGE+ + H+K
Sbjct: 829 GQMERTHNKQEKNRGEEKSKSERECPHSK 857
Score = 46.2 bits (108), Expect = 6e-05
Identities = 92/439 (20%), Positives = 172/439 (39%), Gaps = 86/439 (19%)
Query: 11 KKDF-HPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLN 69
KKD H A K K+ + + + + ++++EE+ + + QES + ++ +E +K+ +
Sbjct: 1000 KKDKKHKAPKR--KQAFHWQPPLEFGEEEEEEIDDKQVT-QESKEKKVSENNETIKDNI- 1055
Query: 70 FMYEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVR-NVRC 128
K E +E+ G+ + + +++ KDD + P + NV C
Sbjct: 1056 --------LKTEKSSEEDLSGKHDTV---TVSSDLDQFTKDDSKLSISPTALNTEENVAC 1104
Query: 129 IKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGR 188
++ ++ E G+ + + TD + E+ R+S ++
Sbjct: 1105 LQ-----NIQHVEESVPNGVEDV----LQTDDN------MEICTPDRSSPAKVEETSPLG 1149
Query: 189 NLTANDPSQEYVASE--GEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQ 246
N + P V + E P+ E +K ++ + K+L ++
Sbjct: 1150 NARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVG----------------- 1192
Query: 247 KSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSD 306
K SSS+S +S+ ST E + +S+ N +KK + + N + + +
Sbjct: 1193 ---------KQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATS 1243
Query: 307 SEEKDK-------SKKRKLHEELSSSHHNR--------EKAKEKPRFLKHESSREDSKWS 351
S + K K + L E+ S + R K R +++ S D +
Sbjct: 1244 SAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTP 1303
Query: 352 HSDSDKKSRTHKHSPEK---RGSERKEGSSRSHGREERSRRSRSRSPGSYKQRE---TRK 405
D D +SR+ S K + R S SH R RSRS S SY+ R +R
Sbjct: 1304 SRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRS----RSRS-STSSYRSRSYSRSRS 1358
Query: 406 RAQRNPGEEQSRRNDSRSH 424
R + G +SR + RS+
Sbjct: 1359 RGWYSRGRTRSRSSSYRSY 1377
Score = 43.9 bits (102), Expect = 3e-04
Identities = 54/260 (20%), Positives = 95/260 (36%), Gaps = 48/260 (18%)
Query: 149 SGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQEYVASEGEEDP 208
S + +++ GS S H E +E S ++ +Y E P
Sbjct: 648 STYSLANIKETGSSSSYHKREKNSESDQSTYS-----------------KYSDRSSESSP 690
Query: 209 EVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSS 268
S + + R R + R SR+K+ H S SSS +S S
Sbjct: 691 RSRSRSSRSRSYSRSYTRS--RSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSIS 748
Query: 269 SSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHN 328
S+ + K+ R KKN S +S S EK + H
Sbjct: 749 -----------SDDGRRAKRRLRSSGKKNSVSHKKHSSSSEK-------------TLHSK 784
Query: 329 REKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSR 388
K +++ ++ S S SDS++ S S +++ E++ R+H ++E++R
Sbjct: 785 YVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEK--EKQGQMERTHNKQEKNR 842
Query: 389 ---RSRSRSPGSYKQRETRK 405
+S+S + ++ T K
Sbjct: 843 GEEKSKSERECPHSKKRTLK 862
Score = 35.0 bits (79), Expect = 0.14
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 353 SDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNP- 411
SDS S + S + E + R H R + +RS+ R + E R + NP
Sbjct: 198 SDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPK 257
Query: 412 -GEEQSRRNDSRSHGTDLYRGEKMYR 436
E+S N+ RS + R + + R
Sbjct: 258 GHSERSDTNEKRSVDSSAKREKPVVR 283
Score = 32.7 bits (73), Expect = 0.69
Identities = 27/125 (21%), Positives = 50/125 (40%), Gaps = 3/125 (2%)
Query: 230 RLEKKKKKKDRKKKKFQKSRSK--HKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEK 287
R + + + + +SRS+ + + ++ S SSS S S +S S S S S +
Sbjct: 1338 RSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHS 1397
Query: 288 KIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPR-FLKHESSRE 346
+ + + S S+ D + + + S S + E R + H S E
Sbjct: 1398 RSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSE 1457
Query: 347 DSKWS 351
S++S
Sbjct: 1458 SSRYS 1462
Score = 31.2 bits (69), Expect = 2.0
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Query: 236 KKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRK 295
K++ KK K + K KKHK+ + E E E +K++ ++ ++
Sbjct: 986 KREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPL----EFGEEEEEEIDDKQVTQESKE 1041
Query: 296 KNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHES 343
K K S +N + + K++K E+LS H + + +F K +S
Sbjct: 1042 K-KVSENNETIKDNILKTEKSS-EEDLSGKHDTVTVSSDLDQFTKDDS 1087
>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo
sapiens]
Length = 558
Score = 67.4 bits (163), Expect = 3e-11
Identities = 88/444 (19%), Positives = 176/444 (39%), Gaps = 27/444 (6%)
Query: 1 MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMG 60
+ +S KK +K I+K +AE Y+ + MQ K++E + +LL+G
Sbjct: 41 VSESLQREAAKKQAMKQTKLEIQKA-LAEDATVYEYDSIYDEMQ---KKKEENNPKLLLG 96
Query: 61 DERVKNGLNFMYEAPPGAKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFG 120
+R ++ + +A KKE +++ E + + E + E + +E + + Q
Sbjct: 97 KDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKLQERA 156
Query: 121 IQV-RNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSEL-IAEMRNSG 178
+ R R V ++ F +N + + S + I E ++ G
Sbjct: 157 EEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFREARSGIKEEKSRG 216
Query: 179 FALKRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKK 238
F+ V +N + + EE+P+ + K D +E+ +
Sbjct: 217 FS--NEVSSKNRIPQEKCILQTDVKVEENPDAD--SDFDAKSSAD-----DEIEETRVNC 267
Query: 239 DRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNK 298
R++K + + K H+S + S S S + + S EK+ + ++K+++
Sbjct: 268 -RREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSR 326
Query: 299 CSGHNNSDSE-EKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDK 357
++ +D + K++ R SH R + ++KPR + + R D W +
Sbjct: 327 DQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPR-ARDQRERSDRVWKREKDRE 385
Query: 358 K------SRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNP 411
K R + + + R SE+ E +S +EE + + R + K R+ R +R
Sbjct: 386 KYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRD---REKREV 442
Query: 412 GEEQSRRNDSRSHGTDLYRGEKMY 435
G + S RN R + R + +
Sbjct: 443 GVQSSERNQDRKESSPNSRAKDKF 466
Score = 48.9 bits (115), Expect = 9e-06
Identities = 61/269 (22%), Positives = 105/269 (39%), Gaps = 35/269 (13%)
Query: 205 EEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSS 264
E +P++ K K LL+ ++ +KK+++ R +KK Q+ R K + +
Sbjct: 88 ENNPKLLLGKDRKPKYIHNLLKAVEI--RKKEQEKRMEKKIQREREMEKGEFDDKEAFVT 145
Query: 265 SSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGH-----NNSDSEEK-----DKSK 314
S+ + E E + K+ SG N + EE+ +
Sbjct: 146 SAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFREA 205
Query: 315 KRKLHEELSSSHHNREKAK----EKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRG 370
+ + EE S N +K ++ L+ + E++ + SD D KS E R
Sbjct: 206 RSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETRV 265
Query: 371 SERKE------------GSSRSHGR---EERSRRSRSRSPGSYKQRETRKRAQRNPGEEQ 415
+ R+E S++H R EER +R + GS R +R +R +Q
Sbjct: 266 NCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGS---RTSRGHEKREDQHQQ 322
Query: 416 SRRNDSRSHGTDL-YRGEKMYREHPGGTH 443
+ D +H TD YR E+ H +H
Sbjct: 323 KQSRDQENHYTDRDYRKERDSHRHREASH 351
Score = 45.4 bits (106), Expect = 1e-04
Identities = 37/213 (17%), Positives = 91/213 (42%), Gaps = 21/213 (9%)
Query: 227 KLDRLEKKKKKKDRKK----KKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESES 282
K + ++K+ +D++ + ++K R H +H+ +S S + + + E
Sbjct: 315 KREDQHQQKQSRDQENHYTDRDYRKERDSH-RHREASHRDSHWKRHEQEDKPRARDQRER 373
Query: 283 NNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHE 342
+++ K ++ + K ++ E+++ +++ S EK+K K +K
Sbjct: 374 SDRVWKREKDREKYSQ---------REQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVR 424
Query: 343 SSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGR-----EERSRRSRSRSPGS 397
R ++ + D +K+ + S +R +RKE S S + +ERS + R+ +
Sbjct: 425 KERYENNDKYRDREKREVGVQSS--ERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDK 482
Query: 398 YKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYR 430
+ +E ++ + G + + + G + R
Sbjct: 483 ERNQEKPSNSESSLGAKHRLTEEGQEKGKEQER 515
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/195 (20%), Positives = 81/195 (41%), Gaps = 18/195 (9%)
Query: 235 KKKKDRKKKKFQKSRSKH-KKHKSSSSSSSSSSSSSSTETSESSSESES-NNKEKKIQRK 292
+K++D + + R H K+H+ + S + + E + +E++ R+
Sbjct: 338 RKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQ 397
Query: 293 KRKKNKCSGHNNSDSEEKDKSKK-----RKLHEELSSSHHNREK------AKEKPRFLKH 341
+ +N+ S + EEK K+K+ RK E + + +REK + E+ + K
Sbjct: 398 QNDQNRPS--EKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRKE 455
Query: 342 ESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQR 401
S +K D ++ ++ + +K ++ K +S S + + G ++R
Sbjct: 456 SSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTEEGQEKGKEQER 515
Query: 402 ---ETRKRAQRNPGE 413
K A+RN E
Sbjct: 516 PPEAVSKFAKRNNEE 530
Score = 37.7 bits (86), Expect = 0.021
Identities = 31/166 (18%), Positives = 71/166 (42%), Gaps = 13/166 (7%)
Query: 188 RNLTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQK 247
R+ ND ++ E EE + K++ +RK +R E K +DR+K++
Sbjct: 394 RDRQQNDQNRPSEKGEKEEKSKA--------KEEHMKVRK-ERYENNDKYRDREKREVGV 444
Query: 248 SRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNN--S 305
S+ + + SS +S + + + + + +KE+ ++ ++ +
Sbjct: 445 QSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTE 504
Query: 306 DSEEKDKSKKRKLHEELSSSHHNREKA--KEKPRFLKHESSREDSK 349
+ +EK K ++R + N E+ + R+L + +R ++K
Sbjct: 505 EGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAK 550
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 67.0 bits (162), Expect = 3e-11
Identities = 47/210 (22%), Positives = 86/210 (40%), Gaps = 14/210 (6%)
Query: 228 LDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEK 287
++ +E ++ K+D ++ K R HKK + E E E +E+
Sbjct: 264 INAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEK-------ERQEIEKERRERERER 316
Query: 288 KIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSRED 347
+ +R++R++ + E++K K+R+ E +R++ KE+ R E R+
Sbjct: 317 ERERERRERER----EREREREREKEKERERERERD---RDRDRTKERDRDRDRERDRDR 369
Query: 348 SKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRA 407
+ SD +K + R ER+ R RE R R R ++RE K
Sbjct: 370 DRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDK 429
Query: 408 QRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
+R+ E++ + R L E Y+E
Sbjct: 430 KRDREEDEEDAYERRKLERKLREKEAAYQE 459
Score = 62.0 bits (149), Expect = 1e-09
Identities = 46/240 (19%), Positives = 106/240 (44%), Gaps = 20/240 (8%)
Query: 201 ASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSS 260
A E EED + L +++ K +LE++K KK++++++ +K R + ++ +
Sbjct: 266 AIEMEEDK-----RDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERER---- 316
Query: 261 SSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKR---K 317
E E E E + +K + ++R++ + + + ++D+ ++R +
Sbjct: 317 -------ERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR 369
Query: 318 LHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGS 377
E S + +R +++EK R + E RE + + +++ + +R ER++
Sbjct: 370 DRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDK 429
Query: 378 SRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
R +E R + +++E + +R E R +R + + R E+ RE
Sbjct: 430 KRDREEDEEDAYERRKLERKLREKEAAYQ-ERLKNWEIRERKKTREYEKEAEREEERRRE 488
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/229 (16%), Positives = 99/229 (43%), Gaps = 7/229 (3%)
Query: 182 KRNVLGRNLTA-NDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDR 240
KR+++ R ++ D ++ +G+++ E + ++ +++++ R+ +R E++++++
Sbjct: 273 KRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERE 332
Query: 241 KKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCS 300
++++ +K R + ++ + E S+++ K R + K
Sbjct: 333 REREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRE 392
Query: 301 GHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSR 360
+ E + + ++ + E RE+ +EK + E ED+ + ++K R
Sbjct: 393 REREREREREREREREREREREREREREREREREKDKKRDREEDEEDA-YERRKLERKLR 451
Query: 361 THKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQR 409
+ + ++R + E R RE R ++RE K A+R
Sbjct: 452 EKEAAYQER-LKNWEIRERKKTREYEKEAEREEE----RRREMAKEAKR 495
Score = 50.1 bits (118), Expect = 4e-06
Identities = 47/229 (20%), Positives = 95/229 (41%), Gaps = 26/229 (11%)
Query: 203 EGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSS 262
E E + E E K +++++ R DR +++ + +DR++ + + ++K S S
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 263 SSSSSSSSTETSESSSESE-----SNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRK 317
S E E E +E++ +R++ ++ + + + +E+D ++RK
Sbjct: 386 EKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK 445
Query: 318 LHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGS 377
L +L REK LK+ RE KK+R ++ E+ R+E +
Sbjct: 446 LERKL------REKEAAYQERLKNWEIRE---------RKKTREYEKEAEREEERRREMA 490
Query: 378 SRSHGREE------RSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRND 420
+ +E R GS Q+ R R + +E+ R+ +
Sbjct: 491 KEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKRE 539
Score = 47.4 bits (111), Expect = 3e-05
Identities = 48/229 (20%), Positives = 87/229 (37%), Gaps = 18/229 (7%)
Query: 226 RKLDRLEKKKKKKDRKKKKF-----QKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSES 280
R DR ++K +DR++++ ++ R + ++ + + E
Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREED 436
Query: 281 ESNNKEK-KIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELS-SSHHNREKAKEKPR- 337
E + E+ K++RK R+K + E +++ K R+ +E RE AKE R
Sbjct: 437 EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRL 496
Query: 338 --FLK-HESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRS 394
FL+ ++ R+D K+ + S + R E ER + E R R
Sbjct: 497 KEFLEDYDDDRDDPKY-YRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGH 555
Query: 395 PG------SYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
P +Q R+R + E +S + + R E M E
Sbjct: 556 PDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604
Score = 42.4 bits (98), Expect = 9e-04
Identities = 54/221 (24%), Positives = 90/221 (40%), Gaps = 28/221 (12%)
Query: 211 EFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSS 270
E+ + +T + +LL L EKK K K K Q K KK +S+ ++ +
Sbjct: 133 EYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKK----KASNGNARPETV 188
Query: 271 TETSESSSESESNNKEKKIQRKKRKK-NKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNR 329
T E + + E+ +++ I+ + S N+ S+E D ++K E+
Sbjct: 189 TNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRF 248
Query: 330 EKAKEKPRFLKHESSREDSKWSHSDSDKKSR----------THKHSPEKRGSERKEGSSR 379
A P L ++ED + DK+ THK E++G + KE R
Sbjct: 249 PVAPLIPYPL---ITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKE---R 302
Query: 380 SHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRND 420
+ER R R R +RE R+R +R E+ R +
Sbjct: 303 QEIEKERRERERER------ERE-RERRERERERERERERE 336
Score = 39.7 bits (91), Expect = 0.006
Identities = 38/204 (18%), Positives = 88/204 (43%), Gaps = 18/204 (8%)
Query: 197 QEYVASEGEEDPEVEF--LKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKK 254
++ + +EG DP+ E ++ +++Q +++ E+++++K K++K ++ + ++
Sbjct: 547 RQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEE 606
Query: 255 HKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCS---GHNNSDSEEKD 311
+ + SS + S+S + + N ++ C H NS +++
Sbjct: 607 PEQKPCLKPTLRPISSAPSVSSASGNATPNTPGD-------ESPCGIIIPHENSPDQQQP 659
Query: 312 KSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDS---KWSHSDSDKKSRTHKHSPEK 368
+ + K+ L N + +P +K + DS K+ DSD R K P
Sbjct: 660 EEHRPKIGLSLKLGASN---SPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLD 716
Query: 369 RGSERKEGSSRSHGREERSRRSRS 392
G + K + + EE+ + +S
Sbjct: 717 YGEDDKNATKGTVNTEEKRKHIKS 740
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 67.0 bits (162), Expect = 3e-11
Identities = 40/236 (16%), Positives = 100/236 (42%), Gaps = 4/236 (1%)
Query: 190 LTANDPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSR 249
L + + + + + +D + + + + ++K ++ DR K+ +++ RK+K+ ++R
Sbjct: 54 LGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNR 113
Query: 250 SKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEE 309
+ K+ + E ++EK+ +R+ K G +++E
Sbjct: 114 DREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDR--DGQRETETER 171
Query: 310 KDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKR 369
+ ++ K E + +R++ EK R + ++ RE + + ++++ T + +
Sbjct: 172 ERDREREKQKERETERDRDRQRDTEKER--ERQTDRERDRQRKTQTERQRETDREGERET 229
Query: 370 GSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHG 425
R+ R G+E R R +++E +K + EE+ R + R G
Sbjct: 230 DRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWG 285
Score = 62.0 bits (149), Expect = 1e-09
Identities = 47/216 (21%), Positives = 100/216 (46%), Gaps = 15/216 (6%)
Query: 226 RKLDRL-EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNN 284
R+ DR+ EK +K++DR +K+ ++ R K K+ ++ + TE +
Sbjct: 79 RERDRVREKTEKERDRDRKRDRERRRKEKE------TNRNRDREKQTEIERDREREKQKG 132
Query: 285 KEKKIQR-KKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHES 343
+E++ R ++R++++ EKD+ +R+ E +RE+ K+K R + E
Sbjct: 133 RERERDRGRERERDRDREKERERQTEKDRDGQRETETE---RERDREREKQKER--ETER 187
Query: 344 SREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGRE--ERSRRSRSRSPGSYKQR 401
R+ + + + ++++ + K +ER+ + R RE R R R R G + R
Sbjct: 188 DRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDR 247
Query: 402 ETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
E ++ +R ++ R+ + + + R E R+
Sbjct: 248 ERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 49.3 bits (116), Expect = 7e-06
Identities = 38/168 (22%), Positives = 60/168 (35%), Gaps = 20/168 (11%)
Query: 290 QRKKRKKNKCSGHNNSDSE---------------EKDKSKKRKLHEELSSSHHNREKAKE 334
Q R H ++D + E+D+ +KR NR + +E
Sbjct: 57 QESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDRE 116
Query: 335 KPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRS 394
K ++ + RE K + D+ + ++ ER+ R RE + R R R
Sbjct: 117 KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
Query: 395 PGSYKQRET-----RKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYRE 437
K+RET R+R E Q+ R R T R + RE
Sbjct: 177 REKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDRE 224
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 66.6 bits (161), Expect = 4e-11
Identities = 71/239 (29%), Positives = 105/239 (43%), Gaps = 33/239 (13%)
Query: 189 NLTANDPSQEYVASEGEEDPE-----VEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKK 243
+L P+ + +G PE VE +K LT + +L + K K + R +
Sbjct: 506 SLAVLQPTPQVTQEQGHLLPERKDFPVESVK-LTEVPVEPVLTVHPESKSKTKTRSRSRG 564
Query: 244 KFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHN 303
+ + SK + +SSSSSSSSSSS+SS+ S SSS S S+ + SG +
Sbjct: 565 RARNKTSKSRS-RSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSS------SSSSTSGSS 617
Query: 304 NSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHK 363
+ DS S SS +R + + R KH S + + D+ R+HK
Sbjct: 618 SRDSSSSTSS---------SSESRSRSRGRGHNRDRKHRRSVDRKR---RDTSGLERSHK 665
Query: 364 HSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSR 422
S K GS R S+ + RS R RS S S + KR+ R+ + +S R D R
Sbjct: 666 SS--KGGSSRDTKGSKD--KNSRSDRKRSISESS----RSGKRSSRSERDRKSDRKDKR 716
Score = 39.7 bits (91), Expect = 0.006
Identities = 32/156 (20%), Positives = 54/156 (34%), Gaps = 17/156 (10%)
Query: 275 ESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKE 334
ES S++++ ++ + R K K++ ++S S S SS
Sbjct: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSS--------- 601
Query: 335 KPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRS 394
SSR S S S S SR S R R H R+ + RRS R
Sbjct: 602 --------SSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRK 653
Query: 395 PGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYR 430
E ++ + ++ + ++ +D R
Sbjct: 654 RRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKR 689
Score = 38.1 bits (87), Expect = 0.016
Identities = 52/247 (21%), Positives = 92/247 (37%), Gaps = 17/247 (6%)
Query: 194 DPSQEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHK 253
+PS+ + E E + E E K + L+ +K+ +++++K+ + + +
Sbjct: 415 EPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKE-SEPQPEPV 473
Query: 254 KHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEE--KD 311
S S S +S S+ + + + + + GH + ++ +
Sbjct: 474 AQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVE 533
Query: 312 KSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGS 371
K ++ E + H K+K K R +R + S S S S + S +
Sbjct: 534 SVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSS-----T 588
Query: 372 ERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRG 431
GSS S G S RS S S S +R + +SR SRS G RG
Sbjct: 589 SSSSGSSSSSGSS--SSRSSSSSSSSTSGSSSRDSSSSTSSSSESR---SRSRG----RG 639
Query: 432 EKMYREH 438
R+H
Sbjct: 640 HNRDRKH 646
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 65.9 bits (159), Expect = 7e-11
Identities = 51/154 (33%), Positives = 72/154 (46%), Gaps = 14/154 (9%)
Query: 301 GHNNSDSEEKDKSKKRKLHEELSSSH-------HNREKAKEKPRFLKHESSREDSKWSHS 353
G +SD+EE+ +SK++K H SSS ++R+K K R SR+ SHS
Sbjct: 2 GRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHS 61
Query: 354 DSDKKSRTHKHSPEKRGSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQ---RN 410
D++ R S GS RK SRS GR + R RSRS ++ +R R + R+
Sbjct: 62 -YDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRS 120
Query: 411 PGEEQSRRNDSRSHGTDLYRG---EKMYREHPGG 441
RR SRS + +G EK +E G
Sbjct: 121 SERSSHRRTRSRSRDRERRKGRDKEKREKEKDKG 154
Score = 59.3 bits (142), Expect = 7e-09
Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 16/168 (9%)
Query: 246 QKSRSKHKK--HKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHN 303
++SRSK KK + SSSSSSS S + S + S S+S + + +Q + ++ H
Sbjct: 10 EESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRRRRHR 69
Query: 304 NSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHK 363
+S S +KR +R +++ + + + + SR S+ S S + R+H
Sbjct: 70 SSSSSSYGSRRKR-----------SRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHS 118
Query: 364 HSPEKRGSERKEGSSRSHGR---EERSRRSRSRSPGSYKQRETRKRAQ 408
S E+ R SR R ++ +R + + G K+ KR +
Sbjct: 119 RSSERSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGE 166
Score = 49.7 bits (117), Expect = 5e-06
Identities = 49/217 (22%), Positives = 80/217 (36%), Gaps = 21/217 (9%)
Query: 218 TKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKK-----------HKSSSSSSSSSS 266
+K+K+K R+ + +KK +KSRSK + + SSSS
Sbjct: 14 SKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRRRRHRSSSS 73
Query: 267 SSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSH 326
SS + S S S K ++QR + K + +S +R H S
Sbjct: 74 SSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRS 133
Query: 327 HNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREER 386
+RE+ K + + RE K D K H + G+ K G E+
Sbjct: 134 RDRERRKGRDK-----EKREKEK----DKGKDKELHNIKRGESGN-IKAGLEHLPPAEQA 183
Query: 387 SRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRS 423
R + + K E K +RN E + R+ + ++
Sbjct: 184 KARLQLVLEAAAKADEALKAKERNEEEAKRRKEEDQA 220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.121 0.337
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,057,124
Number of Sequences: 37866
Number of extensions: 976890
Number of successful extensions: 31701
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 891
Number of HSP's successfully gapped in prelim test: 1034
Number of HSP's that attempted gapping in prelim test: 8450
Number of HSP's gapped (non-prelim): 10306
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.