Search of human proteins with 39753959

Search of human proteins with 39753959

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|39753959 potassium channel tetramerisation domain containing
9 [Homo sapiens]
         (389 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|39753959 potassium channel tetramerisation domain containing ...   783   0.0  
gi|169180181 PREDICTED: similar to potassium channel tetramerisa...   490   e-138
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...   488   e-138
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...   488   e-138
gi|9506651 potassium channel tetramerisation domain containing 5...    97   2e-20
gi|53829365 potassium channel tetramerisation domain containing ...    95   9e-20
gi|169234778 potassium channel tetramerisation domain containing...    84   2e-16
gi|142356950 potassium channel tetramerisation domain containing...    65   8e-11
gi|71143104 potassium channel tetramerisation domain containing ...    64   2e-10
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  61   2e-09
gi|23308551 potassium channel tetramerisation domain containing ...    59   1e-08
gi|46255026 potassium channel tetramerisation domain containing ...    59   1e-08
gi|189571693 potassium channel tetramerisation domain containing...    58   2e-08
gi|189571691 potassium channel tetramerisation domain containing...    58   2e-08
gi|30578412 potassium channel tetramerisation domain containing ...    57   4e-08
gi|19923973 potassium channel tetramerisation domain containing ...    56   6e-08
gi|45387953 potassium channel tetramerization domain containing ...    55   8e-08
gi|13994353 potassium channel tetramerisation domain containing ...    55   8e-08
gi|55926200 potassium channel tetramerisation domain containing ...    53   5e-07
gi|146198864 potassium channel tetramerisation domain containing...    52   1e-06
gi|194018443 potassium channel tetramerisation domain containing...    51   2e-06
gi|194018441 potassium channel tetramerisation domain containing...    51   2e-06
gi|194018439 potassium channel tetramerisation domain containing...    51   2e-06
gi|38198663 potassium channel tetramerisation domain containing ...    50   3e-06
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       48   2e-05
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       48   2e-05
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    47   2e-05
gi|218505694 potassium channel tetramerisation domain containing...    44   2e-04
gi|209969708 potassium channel tetramerisation domain containing...    44   2e-04
gi|40217617 potassium channel tetramerisation domain containing ...    44   2e-04

>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score =  783 bits (2022), Expect = 0.0
 Identities = 389/389 (100%), Positives = 389/389 (100%)

Query: 1   MRRVTLFLNGSPKNGKVVAVYGTLSDLLSVASSKLGIKATSVYNGKGGLIDDIALIRDDD 60
           MRRVTLFLNGSPKNGKVVAVYGTLSDLLSVASSKLGIKATSVYNGKGGLIDDIALIRDDD
Sbjct: 1   MRRVTLFLNGSPKNGKVVAVYGTLSDLLSVASSKLGIKATSVYNGKGGLIDDIALIRDDD 60

Query: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMF 120
           VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMF
Sbjct: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMF 120

Query: 121 KDKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSL 180
           KDKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSL
Sbjct: 121 KDKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSL 180

Query: 181 IEHLEVAIKNSQPPEDHSPISRKEFVRFLLATPTKSELRCQGLNFSGADLSRLDLRYINF 240
           IEHLEVAIKNSQPPEDHSPISRKEFVRFLLATPTKSELRCQGLNFSGADLSRLDLRYINF
Sbjct: 181 IEHLEVAIKNSQPPEDHSPISRKEFVRFLLATPTKSELRCQGLNFSGADLSRLDLRYINF 240

Query: 241 KMANLSRCNLAHANLCCANLERADLSGSVLDCANLQGVKMLCSNAEGASLKLCNFEDPSG 300
           KMANLSRCNLAHANLCCANLERADLSGSVLDCANLQGVKMLCSNAEGASLKLCNFEDPSG
Sbjct: 241 KMANLSRCNLAHANLCCANLERADLSGSVLDCANLQGVKMLCSNAEGASLKLCNFEDPSG 300

Query: 301 LKANLEGANLKGVDMEGSQMTGINLRVATLKNAKLKNCNLRGATLAGTDLENCDLSGCDL 360
           LKANLEGANLKGVDMEGSQMTGINLRVATLKNAKLKNCNLRGATLAGTDLENCDLSGCDL
Sbjct: 301 LKANLEGANLKGVDMEGSQMTGINLRVATLKNAKLKNCNLRGATLAGTDLENCDLSGCDL 360

Query: 361 QEANLRGSNVKGAIFEEMLTPLHMSQSVR 389
           QEANLRGSNVKGAIFEEMLTPLHMSQSVR
Sbjct: 361 QEANLRGSNVKGAIFEEMLTPLHMSQSVR 389


>gi|169180181 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score =  490 bits (1261), Expect = e-138
 Identities = 240/261 (91%), Positives = 249/261 (95%)

Query: 1   MRRVTLFLNGSPKNGKVVAVYGTLSDLLSVASSKLGIKATSVYNGKGGLIDDIALIRDDD 60
           MRRVTLFLNGSPKNGKVVA YGT  DLLSVASSKLGIKATSVYNGKGGL DDI LIRDDD
Sbjct: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGKGGLNDDIVLIRDDD 60

Query: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMF 120
           VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTL+VGG+YFTTT STLVNKEPD MLAHMF
Sbjct: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120

Query: 121 KDKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSL 180
           KDKGVWGNKQDHRGAFLID+SPEYFEPILNYLRHGQLIVNDGI+LLGVLEEARFFGIDSL
Sbjct: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180

Query: 181 IEHLEVAIKNSQPPEDHSPISRKEFVRFLLATPTKSELRCQGLNFSGADLSRLDLRYINF 240
           IEHL+VAIKNSQPPEDH PISRKEFVR LLATPTKSE+RCQGLNFSGA+LS LDLRYINF
Sbjct: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240

Query: 241 KMANLSRCNLAHANLCCANLE 261
           K+ NL+ CNLAHANLCCANLE
Sbjct: 241 KITNLNCCNLAHANLCCANLE 261


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score =  488 bits (1256), Expect = e-138
 Identities = 239/261 (91%), Positives = 248/261 (95%)

Query: 1   MRRVTLFLNGSPKNGKVVAVYGTLSDLLSVASSKLGIKATSVYNGKGGLIDDIALIRDDD 60
           MRRVTLFLNGSPKNGKVVA YGT  DLLSVASSKLGIKATSVYNG GGL DDI LIRDDD
Sbjct: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD 60

Query: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMF 120
           VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTL+VGG+YFTTT STLVNKEPD MLAHMF
Sbjct: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120

Query: 121 KDKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSL 180
           KDKGVWGNKQDHRGAFLID+SPEYFEPILNYLRHGQLIVNDGI+LLGVLEEARFFGIDSL
Sbjct: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180

Query: 181 IEHLEVAIKNSQPPEDHSPISRKEFVRFLLATPTKSELRCQGLNFSGADLSRLDLRYINF 240
           IEHL+VAIKNSQPPEDH PISRKEFVR LLATPTKSE+RCQGLNFSGA+LS LDLRYINF
Sbjct: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240

Query: 241 KMANLSRCNLAHANLCCANLE 261
           K+ NL+ CNLAHANLCCANLE
Sbjct: 241 KITNLNCCNLAHANLCCANLE 261


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score =  488 bits (1256), Expect = e-138
 Identities = 239/261 (91%), Positives = 248/261 (95%)

Query: 1   MRRVTLFLNGSPKNGKVVAVYGTLSDLLSVASSKLGIKATSVYNGKGGLIDDIALIRDDD 60
           MRRVTLFLNGSPKNGKVVA YGT  DLLSVASSKLGIKATSVYNG GGL DDI LIRDDD
Sbjct: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD 60

Query: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMF 120
           VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTL+VGG+YFTTT STLVNKEPD MLAHMF
Sbjct: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120

Query: 121 KDKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSL 180
           KDKGVWGNKQDHRGAFLID+SPEYFEPILNYLRHGQLIVNDGI+LLGVLEEARFFGIDSL
Sbjct: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180

Query: 181 IEHLEVAIKNSQPPEDHSPISRKEFVRFLLATPTKSELRCQGLNFSGADLSRLDLRYINF 240
           IEHL+VAIKNSQPPEDH PISRKEFVR LLATPTKSE+RCQGLNFSGA+LS LDLRYINF
Sbjct: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240

Query: 241 KMANLSRCNLAHANLCCANLE 261
           K+ NL+ CNLAHANLCCANLE
Sbjct: 241 KITNLNCCNLAHANLCCANLE 261


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 54/118 (45%), Positives = 72/118 (61%), Gaps = 6/118 (5%)

Query: 85  GFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEY 144
           G  + W+ LNVGG YF TTR TL  ++P S L  + +      + +D  GA+LIDR P Y
Sbjct: 40  GSVSKWVRLNVGGTYFLTTRQTLC-RDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTY 98

Query: 145 FEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAI-----KNSQPPEDH 197
           F P+LNYLRHG+L++N  +   GVLEEA F+ I SLI+ ++  I     K SQ P  H
Sbjct: 99  FGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPVKH 156


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 95.1 bits (235), Expect = 9e-20
 Identities = 50/112 (44%), Positives = 70/112 (62%), Gaps = 2/112 (1%)

Query: 90  WLTLNVGGRYFTTTRSTLVNKEPDSMLAHMF-KDKGVWGNKQDHRGAFLIDRSPEYFEPI 148
           W+ LNVGG YF TTR TL  +EP S L  +  ++     + +D  GA+LIDR P YF PI
Sbjct: 73  WVRLNVGGTYFVTTRQTL-GREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPI 131

Query: 149 LNYLRHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQPPEDHSPI 200
           LNYLRHG+LI+   +   GVLEEA F+ I SL+  ++  I++++      P+
Sbjct: 132 LNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPV 183


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 51/127 (40%), Positives = 74/127 (58%), Gaps = 10/127 (7%)

Query: 76  DSKPPEGL----LGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQD 131
           ++ PP G      G    W+ LNVGG  F TTR TL  +E  S L+ + + + +  ++ D
Sbjct: 14  EAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLC-REQKSFLSRLCQGEELQSDR-D 71

Query: 132 HRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNS 191
             GA+LIDR P YF PILN+LRHG+L+++  +   GVLEEA F+ I  LI      IK+ 
Sbjct: 72  ETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIR----IIKDR 127

Query: 192 QPPEDHS 198
              +D++
Sbjct: 128 MEEKDYT 134


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 51/125 (40%), Positives = 62/125 (49%), Gaps = 14/125 (11%)

Query: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPILNYL 152
           LNVGG + TTT  TL  K P S LA MF          D  G F IDR   YF PIL+YL
Sbjct: 37  LNVGGEFHTTTLGTL-RKFPGSKLAEMFSSLAKAST--DAEGRFFIDRPSTYFRPILDYL 93

Query: 153 RHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQPPEDHSPISRKEFVRFLLAT 212
           R GQ+      ++  V  EA+F+ I  L++ LE       P      +SRK+   FLL  
Sbjct: 94  RTGQVPTQ---HIPEVYREAQFYEIKPLVKLLE-----DMPQIFGEQVSRKQ---FLLQV 142

Query: 213 PTKSE 217
           P  SE
Sbjct: 143 PGYSE 147


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 4/99 (4%)

Query: 88  TDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEP 147
           +D +TLNVGG+ +TT+ +TL +  PDSML  MF  K     K+D +G   IDR  + F  
Sbjct: 2   SDPITLNVGGKLYTTSLATLTSF-PDSMLGAMFSGK--MPTKRDSQGNCFIDRDGKVFRY 58

Query: 148 ILNYLRHGQLIVNDGINLLGVL-EEARFFGIDSLIEHLE 185
           ILN+LR   L + +    +G+L  EA F+ +  LIE L+
Sbjct: 59  ILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQ 97


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 4/94 (4%)

Query: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPILNYL 152
           LNVGG+ F+T+R TL    PDS  + +    G     +D  GA  IDR P  F PILN+L
Sbjct: 23  LNVGGKRFSTSRQTLT-WIPDSFFSSLLS--GRISTLKDETGAIFIDRDPTVFAPILNFL 79

Query: 153 RHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEV 186
           R  +L    G++   +L EA+F+G+  L+  L++
Sbjct: 80  RTKELDPR-GVHGSSLLHEAQFYGLTPLVRRLQL 112


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 45/131 (34%), Positives = 66/131 (50%), Gaps = 14/131 (10%)

Query: 68  EPFIDPQTDSKPPEG-----LLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKD 122
           + F++P T +    G     L     + + LN+GG +FTT  STL   E D+MLA MF  
Sbjct: 25  DDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYE-DTMLAAMFSG 83

Query: 123 KGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSLIE 182
           +       D  G + IDR   +F  +LN+LR G L   + +    V +EA+++ I  L+E
Sbjct: 84  RHYIPT--DSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR--AVYKEAQYYAIGPLLE 139

Query: 183 HLEVAIKNSQP 193
            LE    N QP
Sbjct: 140 QLE----NMQP 146


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 4/92 (4%)

Query: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPILNYL 152
           LNVGG  F+T+R TL+   PDS  + +    G     +D  GA  IDR P  F PILN+L
Sbjct: 22  LNVGGTRFSTSRQTLM-WIPDSFFSSLLS--GRISTLRDETGAIFIDRDPAAFAPILNFL 78

Query: 153 RHGQLIVNDGINLLGVLEEARFFGIDSLIEHL 184
           R  +L +  G+++  +  EA F+GI  L+  L
Sbjct: 79  RTKELDLR-GVSINVLRHEAEFYGITPLVRRL 109


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 39/98 (39%), Positives = 57/98 (58%), Gaps = 4/98 (4%)

Query: 88  TDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEP 147
           TD +TLNVGG  +TT+ +TL  + PDSML  MF   G +   +D +G + IDR    F  
Sbjct: 11  TDPVTLNVGGHLYTTSLTTL-TRYPDSMLGAMF--GGDFPTARDPQGNYFIDRDGPLFRY 67

Query: 148 ILNYLRHGQLIVNDGINLLGVL-EEARFFGIDSLIEHL 184
           +LN+LR  +L +        +L +EA F+ I+ LI+ L
Sbjct: 68  VLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 39/98 (39%), Positives = 57/98 (58%), Gaps = 4/98 (4%)

Query: 88  TDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEP 147
           TD +TLNVGG  +TT+ +TL  + PDSML  MF   G +   +D +G + IDR    F  
Sbjct: 11  TDPVTLNVGGHLYTTSLTTL-TRYPDSMLGAMF--GGDFPTARDPQGNYFIDRDGPLFRY 67

Query: 148 ILNYLRHGQLIVNDGINLLGVL-EEARFFGIDSLIEHL 184
           +LN+LR  +L +        +L +EA F+ I+ LI+ L
Sbjct: 68  VLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 44/115 (38%), Positives = 63/115 (54%), Gaps = 7/115 (6%)

Query: 87  HTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFE 146
           ++ ++ LNVGG    TT  TL  +  D+ML  MF   G      D  G  LIDRS  +F 
Sbjct: 39  NSKYVKLNVGGSLHYTTLRTLTGQ--DTMLKAMFS--GRVEVLTDAGGWVLIDRSGRHFG 94

Query: 147 PILNYLRHGQLIVNDGINLLG-VLEEARFFGIDSLIEHLEVAIKNSQPPEDHSPI 200
            ILNYLR G + + +    LG +L EAR++ +  LIE  ++A++  Q  E  SP+
Sbjct: 95  TILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQ--QKRETLSPL 147


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 41/116 (35%), Positives = 59/116 (50%), Gaps = 6/116 (5%)

Query: 89  DWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPI 148
           D + LNVGG+ + T R T+V+  PDS+L  MF  +      +D +G F +DR    F  I
Sbjct: 34  DIVELNVGGQVYVTRRCTVVSV-PDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYI 92

Query: 149 LNYLRHGQLIVNDGINLLGVLE-EARFFGIDSLIEHLEVAIKNSQPPEDHSPISRK 203
           L+YLR  QL++ D       L+ EA +F +  L+  L       Q P    P SR+
Sbjct: 93  LDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGA----PQQPGPGPPPSRR 144


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 43/100 (43%), Positives = 57/100 (57%), Gaps = 8/100 (8%)

Query: 89  DWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPI 148
           D L LNVGG  +T  R +L   + DSMLA MF   G +  K D  GA +IDR    F+ +
Sbjct: 12  DVLRLNVGGCIYTARRESLCRFK-DSMLASMFS--GRFPLKTDESGACVIDRDGRLFKYL 68

Query: 149 LNYLRHGQL-IVNDGINLLGVLEEARFFGID---SLIEHL 184
           L+YL HG++ I  D    + + EEA +FGI    SL +HL
Sbjct: 69  LDYL-HGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHL 107


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 44/135 (32%), Positives = 68/135 (50%), Gaps = 10/135 (7%)

Query: 90  WLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPIL 149
           ++ LNVGG  + TT  TL  +  D+ML  MF   G      D  G  LIDR  ++F  IL
Sbjct: 33  YVKLNVGGALYYTTMQTLTKQ--DTMLKAMFS--GRMEVLTDSEGWILIDRCGKHFGTIL 88

Query: 150 NYLRHGQL-IVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQPPEDHSPI----SRKE 204
           NYLR G + +      +  +L EA+++ +  L+E  + A++N    E    +    S KE
Sbjct: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKE 148

Query: 205 FVRFLLATPTKSELR 219
             + L+AT  K  ++
Sbjct: 149 EQK-LIATSNKPAVK 162


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 37/95 (38%), Positives = 53/95 (55%), Gaps = 4/95 (4%)

Query: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNK--QDHRGAFLIDRSPEYFEPILN 150
           LNVGG+ + T  STL++  P S+L  MF  K    N   +D +G F IDR    F  IL+
Sbjct: 29  LNVGGQVYFTRHSTLISI-PHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILD 87

Query: 151 YLRHGQLIVNDGINLLGVLE-EARFFGIDSLIEHL 184
           YLR  Q+++ D     G L+ EA +F +  L++ L
Sbjct: 88  YLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 34/96 (35%), Positives = 53/96 (55%), Gaps = 4/96 (4%)

Query: 91  LTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPILN 150
           +TLNVGG  + T + TL  K PD+ L  +   K +     D  G + IDR    F  +LN
Sbjct: 35  MTLNVGGYLYITQKQTLT-KYPDTFLEGIVNGKILCPFDAD--GHYFIDRDGLLFRHVLN 91

Query: 151 YLRHGQLIVNDGINLLGVL-EEARFFGIDSLIEHLE 185
           +LR+G+L++ +G     +L +EA FF +  L E ++
Sbjct: 92  FLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVK 127


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/148 (27%), Positives = 71/148 (47%), Gaps = 17/148 (11%)

Query: 41  SVYNGKGGLIDDIALIRDDDVLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYF 100
           S    +GG +  ++L R        +G P     T S  P          + ++VGG  +
Sbjct: 18  STGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAP----------VHIDVGGHMY 67

Query: 101 TTTRSTLVNKEPDSMLAHMFK--DKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLI 158
           T++ +TL  K PDS ++ +F   +  V  + + H   + IDR  E F  +L++LR  +L+
Sbjct: 68  TSSLATLT-KYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGEIFRYVLSFLRTSKLL 123

Query: 159 VNDGINLLGVL-EEARFFGIDSLIEHLE 185
           + D      +L EEAR++ +  ++  LE
Sbjct: 124 LPDDFKDFSLLYEEARYYQLQPMVRELE 151


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/148 (27%), Positives = 71/148 (47%), Gaps = 17/148 (11%)

Query: 41  SVYNGKGGLIDDIALIRDDDVLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYF 100
           S    +GG +  ++L R        +G P     T S  P          + ++VGG  +
Sbjct: 18  STGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAP----------VHIDVGGHMY 67

Query: 101 TTTRSTLVNKEPDSMLAHMFK--DKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLI 158
           T++ +TL  K PDS ++ +F   +  V  + + H   + IDR  E F  +L++LR  +L+
Sbjct: 68  TSSLATLT-KYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGEIFRYVLSFLRTSKLL 123

Query: 159 VNDGINLLGVL-EEARFFGIDSLIEHLE 185
           + D      +L EEAR++ +  ++  LE
Sbjct: 124 LPDDFKDFSLLYEEARYYQLQPMVRELE 151


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 40/148 (27%), Positives = 71/148 (47%), Gaps = 17/148 (11%)

Query: 41  SVYNGKGGLIDDIALIRDDDVLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYF 100
           S    +GG +  ++L R        +G P     T S  P          + ++VGG  +
Sbjct: 18  STGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAP----------VHIDVGGHMY 67

Query: 101 TTTRSTLVNKEPDSMLAHMFK--DKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLI 158
           T++ +TL  K PDS ++ +F   +  V  + + H   + IDR  E F  +L++LR  +L+
Sbjct: 68  TSSLATLT-KYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGEIFRYVLSFLRTSKLL 123

Query: 159 VNDGINLLGVL-EEARFFGIDSLIEHLE 185
           + D      +L EEAR++ +  ++  LE
Sbjct: 124 LPDDFKDFSLLYEEARYYQLQPMVRELE 151


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 9/112 (8%)

Query: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQ-------DHRGAFLIDRSPEYF 145
           LNVGG+ + T  STL++  PDS LA MF      G  +       D R  F IDR    F
Sbjct: 48  LNVGGQVYVTKHSTLLSV-PDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLF 106

Query: 146 EPILNYLRHGQLIVNDGI-NLLGVLEEARFFGIDSLIEHLEVAIKNSQPPED 196
             +L+YLR  QL + +       +L EA +F +  L++ L   +       D
Sbjct: 107 RYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLND 158


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 10/107 (9%)

Query: 91  LTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHR---GAFLIDRSPEYFEP 147
           +TLNVGG+ FTT  ST + + P S LA M       G  Q+ +   G   +DR  + F  
Sbjct: 7   VTLNVGGKIFTTRFST-IKQFPASRLARMLD-----GRDQEFKMVGGQIFVDRDGDLFSF 60

Query: 148 ILNYLR-HGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQP 193
           IL++LR H  L+  +  + L +  EA F+ + SL++ L   +   +P
Sbjct: 61  ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRP 107


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 10/107 (9%)

Query: 91  LTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHR---GAFLIDRSPEYFEP 147
           +TLNVGG+ FTT  ST + + P S LA M       G  Q+ +   G   +DR  + F  
Sbjct: 7   VTLNVGGKIFTTRFST-IKQFPASRLARMLD-----GRDQEFKMVGGQIFVDRDGDLFSF 60

Query: 148 ILNYLR-HGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQP 193
           IL++LR H  L+  +  + L +  EA F+ + SL++ L   +   +P
Sbjct: 61  ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRP 107


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 18/160 (11%)

Query: 67  GEPFIDPQTDSKPPEGLLGFH-----TDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFK 121
           G+  + P + +KP   L GF        ++ LNVGG  + TT   L     D+ML  MF 
Sbjct: 3   GDTCLCPASGAKPK--LSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRH--DTMLKAMFS 58

Query: 122 DKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQL-IVNDGINLLGVLEEARFFGIDSL 180
             G      D  G  LIDR  ++F  ILNYLR   + +  +   +  ++ EA+++ I  L
Sbjct: 59  --GRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL 116

Query: 181 IEHLEVAI---KNSQPPEDHSPI--SRKEFVRFLLATPTK 215
           +   + A+   K+S  P  + PI  S KE  R L+ + TK
Sbjct: 117 VNMCQSALQDKKDSYQPVCNIPIITSLKEEER-LIESSTK 155


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 29/96 (30%), Positives = 54/96 (56%), Gaps = 7/96 (7%)

Query: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFK--DKGVWGNKQDHRGAFLIDRSPEYFEPILN 150
           ++VGG  +T++ +TL  K P+S +  +F   +  V  + + H   + IDR  + F  ILN
Sbjct: 642 IDVGGHMYTSSLATLT-KYPESRIGRLFDGTEPIVLDSLKQH---YFIDRDGQMFRYILN 697

Query: 151 YLRHGQLIVNDGINLLGVL-EEARFFGIDSLIEHLE 185
           +LR  +L++ D      +L EEA++F +  ++  +E
Sbjct: 698 FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME 733


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 29/96 (30%), Positives = 54/96 (56%), Gaps = 7/96 (7%)

Query: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFK--DKGVWGNKQDHRGAFLIDRSPEYFEPILN 150
           ++VGG  +T++ +TL  K P+S +  +F   +  V  + + H   + IDR  + F  ILN
Sbjct: 34  IDVGGHMYTSSLATLT-KYPESRIGRLFDGTEPIVLDSLKQH---YFIDRDGQMFRYILN 89

Query: 151 YLRHGQLIVNDGINLLGVL-EEARFFGIDSLIEHLE 185
           +LR  +L++ D      +L EEA++F +  ++  +E
Sbjct: 90  FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME 125


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 29/96 (30%), Positives = 54/96 (56%), Gaps = 7/96 (7%)

Query: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFK--DKGVWGNKQDHRGAFLIDRSPEYFEPILN 150
           ++VGG  +T++ +TL  K P+S +  +F   +  V  + + H   + IDR  + F  ILN
Sbjct: 34  IDVGGHMYTSSLATLT-KYPESRIGRLFDGTEPIVLDSLKQH---YFIDRDGQMFRYILN 89

Query: 151 YLRHGQLIVNDGINLLGVL-EEARFFGIDSLIEHLE 185
           +LR  +L++ D      +L EEA++F +  ++  +E
Sbjct: 90  FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME 125


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,316,001
Number of Sequences: 37866
Number of extensions: 623408
Number of successful extensions: 1580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1190
Number of HSP's gapped (non-prelim): 343
length of query: 389
length of database: 18,247,518
effective HSP length: 104
effective length of query: 285
effective length of database: 14,309,454
effective search space: 4078194390
effective search space used: 4078194390
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.