Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 38569484
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38569484 kinesin family member 21A [Homo sapiens]
(1661 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38569484 kinesin family member 21A [Homo sapiens] 3249 0.0
gi|83716024 kinesin family member 21B [Homo sapiens] 1893 0.0
gi|116686122 kinesin family member 4 [Homo sapiens] 472 e-132
gi|150010604 kinesin family member 4B [Homo sapiens] 461 e-129
gi|30794488 kinesin family member 27 [Homo sapiens] 368 e-101
gi|203096856 kinesin family member 7 [Homo sapiens] 320 6e-87
gi|4758650 kinesin family member 5C [Homo sapiens] 281 5e-75
gi|4758648 kinesin family member 5B [Homo sapiens] 273 1e-72
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 272 2e-72
gi|4758646 kinesin family member 3B [Homo sapiens] 269 1e-71
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 269 1e-71
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 269 1e-71
gi|46852174 kinesin family member 3A [Homo sapiens] 266 2e-70
gi|9910266 kinesin family member 15 [Homo sapiens] 263 1e-69
gi|45446749 kinesin family member 5A [Homo sapiens] 259 1e-68
gi|46852172 kinesin family member 13B [Homo sapiens] 251 3e-66
gi|71061468 centromere protein E [Homo sapiens] 244 7e-64
gi|41352705 kinesin family member 3C [Homo sapiens] 243 9e-64
gi|7661878 kinesin family member 14 [Homo sapiens] 237 6e-62
gi|156616271 kinesin family member 19 [Homo sapiens] 237 6e-62
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 236 1e-61
gi|13699824 kinesin family member 11 [Homo sapiens] 236 2e-61
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 236 2e-61
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 236 2e-61
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 236 2e-61
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 236 2e-61
gi|148612831 kinesin family member 18A [Homo sapiens] 231 3e-60
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 227 6e-59
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 227 6e-59
gi|40254834 kinesin family member 1C [Homo sapiens] 219 2e-56
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 3249 bits (8425), Expect = 0.0
Identities = 1661/1661 (100%), Positives = 1661/1661 (100%)
Query: 1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 60
MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ
Sbjct: 1 MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQ 60
Query: 61 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 120
QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH
Sbjct: 61 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 120
Query: 121 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 180
LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED
Sbjct: 121 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 180
Query: 181 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 240
STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC
Sbjct: 181 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 240
Query: 241 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 300
PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG
Sbjct: 241 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 300
Query: 301 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 360
LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN
Sbjct: 301 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 360
Query: 361 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 420
TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND
Sbjct: 361 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESIND 420
Query: 421 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 480
MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH
Sbjct: 421 MFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIH 480
Query: 481 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 540
SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL
Sbjct: 481 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 540
Query: 541 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 600
AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE
Sbjct: 541 AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDE 600
Query: 601 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 660
EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT
Sbjct: 601 EEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQT 660
Query: 661 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 720
LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ
Sbjct: 661 LKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQ 720
Query: 721 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 780
RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR
Sbjct: 721 RLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNR 780
Query: 781 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 840
EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS
Sbjct: 781 EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLS 840
Query: 841 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 900
SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV
Sbjct: 841 SSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRV 900
Query: 901 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 960
FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK
Sbjct: 901 FISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK 960
Query: 961 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 1020
ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT
Sbjct: 961 ENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACT 1020
Query: 1021 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1080
LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL
Sbjct: 1021 LTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1080
Query: 1081 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1140
NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA
Sbjct: 1081 NPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKA 1140
Query: 1141 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1200
RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP
Sbjct: 1141 RRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP 1200
Query: 1201 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP 1260
PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP
Sbjct: 1201 PPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPP 1260
Query: 1261 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR 1320
SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR
Sbjct: 1261 SSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR 1320
Query: 1321 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV 1380
AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV
Sbjct: 1321 AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSV 1380
Query: 1381 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ 1440
KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ
Sbjct: 1381 KYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQ 1440
Query: 1441 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG 1500
INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG
Sbjct: 1441 INQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITG 1500
Query: 1501 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK 1560
SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK
Sbjct: 1501 SKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQK 1560
Query: 1561 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC 1620
DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC
Sbjct: 1561 DLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAIC 1620
Query: 1621 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1661
VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN
Sbjct: 1621 VNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1661
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 1893 bits (4904), Expect = 0.0
Identities = 977/1642 (59%), Positives = 1245/1642 (75%), Gaps = 64/1642 (3%)
Query: 10 VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCI 69
V+VAVRIRPQL+KEKIEGCHICTSVTPGEPQV LGKDKAFT+D+VFD+D+ QEQIY C+
Sbjct: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCV 68
Query: 70 EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKSIEEKK 129
KLIEGCFEGYNATV AYGQTGAGKTYTMGTGFD+ EEE GII RA+ HLF I E+K
Sbjct: 69 SKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLFGGIAERK 128
Query: 130 HIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGIYTVG 189
A + G+ P+FKV+AQFLELYNEE+LDLFD+TRD D + ++SNI+IHED+ GGIYT G
Sbjct: 129 RRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGIYTTG 188
Query: 190 VTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDADNAT 249
VT+R ++++ E++QCLK GALSRTTASTQMNVQSSRSHAIFTIH+CQ R+C Q D N
Sbjct: 189 VTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDLVNEA 248
Query: 250 DNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVIS 309
+ + +E+ETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVIS
Sbjct: 249 VTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVIS 308
Query: 310 ALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRAR 369
ALGD+SK+ HVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRAR
Sbjct: 309 ALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRAR 368
Query: 370 NIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQ 429
NIKNKV+VNQD+ SQQI+ALR+EI RLQMELMEYK GKR+I E+G E +D+F ENAMLQ
Sbjct: 369 NIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQ 428
Query: 430 TENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDL 489
EN LR+R+KAMQE +DA+ +R+TQL+S +AN +LA+AG+GNE I +I +YI+EIE+L
Sbjct: 429 KENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEEL 488
Query: 490 RAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTI----LSSDKETIEIIDLAKKDL 545
R KLLESEA+NE+LR++L+RA+AR+PY G+S +P SS ++ E+I AK+DL
Sbjct: 489 RTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDL 548
Query: 546 EKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEE 605
E+LK+KE R+++ KE + K +++ E + NE E EE + +EEE E
Sbjct: 549 ERLKKKEVRQRRKSPEKE--AFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGRE 606
Query: 606 EEEDDIDGGESSDESDSESDEK-ANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQ 664
+E++D ES +SDS+ +EK N+QADLA++TCEI IKQKLIDELENSQ+RLQTLK Q
Sbjct: 607 DEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQ 666
Query: 665 YEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQA 724
YEEKL++LQ+KIRDTQLERD+VLQNL ++E Y+EEKA K++++YEK+L+ MN++LQ+LQA
Sbjct: 667 YEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQA 726
Query: 725 AQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQ 784
AQKEHARLLKNQS+YE++LKKLQ +V EMKK KV LMKQM+EEQ++ RL E++RNREIAQ
Sbjct: 727 AQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQ 786
Query: 785 LKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDA 844
LKK+QR+++ Q+R LE+QKR QE+VLRRKT+EV+ALRR +PMS++VAG+ K D+
Sbjct: 787 LKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDS 846
Query: 845 PAQDTGSSAAAVETDASRTGAQQKMRIPVARVQAL----PTPATNGN---RKKYQRKGLT 897
A+ + S+ ++ E ++ +R ++ P P NG RKK+Q+KG +
Sbjct: 847 GAEVSASTTSS-EAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGAS 905
Query: 898 GRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREK 957
SK AR+KWQ LERR+ DI+MQ+MTI N+EADM RL+K+REEL +E L ++RE+
Sbjct: 906 QS--FSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKRER 963
Query: 958 IVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVIN 1017
+ E+ E +K + + EE+E L ANIDYIND I+DCQA I+Q+EE KEE ++ D + VI+
Sbjct: 964 LQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVIS 1023
Query: 1018 ACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEK 1077
+C+L EAR LLD+FL I+KGLQ AQKEAQI++LEGRL+QT++ ++QN LL L+EK
Sbjct: 1024 SCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREK 1083
Query: 1078 AELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMK-LCGEVKP 1136
AE +PEL AL+ + Q EN STDE+ S SEGS S MK
Sbjct: 1084 AEAHPELQALIYNVQQ-------ENGYASTDEEI---SEFSEGSFSQSFTMKGSTSHDDF 1133
Query: 1137 KNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREK 1196
K K+ + + QM+ + A+ D ST ++ L + E +E G+ R++
Sbjct: 1134 KFKSEPKLSAQMKAVSAECLGPPLDIST--KNITKSLASLVEIKEDGVGFSVRDPYYRDR 1191
Query: 1197 ELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEAS 1256
+S LP++ + RQS + E SP+TRRK+Y++ + + +++
Sbjct: 1192 -VSRTVSLPTRGSTFPRQS-----RATETSPLTRRKSYDRGQPIR----------STDVG 1235
Query: 1257 LSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPAS 1316
+PPSSPP+RPRN+ NVF+RLT +Q S +GII+P +
Sbjct: 1236 FTPPSSPPTRPRNDRNVFSRLTSNQSQGSALD------------------KGIISPVGGA 1277
Query: 1317 KGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNN 1376
KG R PLQC+ +AEGHTK +LC+D+TD+LLFTGSKDR+CK+WNLVTGQEI +L GHPNN
Sbjct: 1278 KGARTAPLQCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNN 1337
Query: 1377 VVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPS 1436
VVS+KYC+++ LVF+VSTSYIKVWDIRDSAKCIRTLTSSGQV GDAC+A+++R +
Sbjct: 1338 VVSIKYCSHSGLVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVISGDACAATSTRAITSAQ 1397
Query: 1437 GENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDL 1496
GE+QINQIAL+P+GT LYAASGNAVR+W+L RFQ GKLTGH+GPVMCLTV Q +S DL
Sbjct: 1398 GEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQTASQHDL 1457
Query: 1497 IITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWD 1556
++TGSKDHY+KMF++ E GT+ PTHNFEPPHYDGIE L IQGD LFSGSRDNGIKKWD
Sbjct: 1458 VVTGSKDHYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWD 1517
Query: 1557 LTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPI 1616
L Q++L+QQ+PNAHKDWVCAL +P P+LLS CR G++KVWN+D F P+GE+KGHDSPI
Sbjct: 1518 LDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTPIGEIKGHDSPI 1577
Query: 1617 NAICVNSTHIFTAADDRTVRIW 1638
NAIC N+ HIFTA+ D V++W
Sbjct: 1578 NAICTNAKHIFTASSDCRVKLW 1599
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 472 bits (1215), Expect = e-132
Identities = 336/1083 (31%), Positives = 541/1083 (49%), Gaps = 176/1083 (16%)
Query: 10 VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCI 69
VRVA+R RP + KE EGC +C S PGEPQV +G DK+FT+D+VFD ++QE+++ +
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAV 69
Query: 70 EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEE-ELGIISRAVKHLFKSIEEK 128
LI+G F+GYNATV AYGQTG+GKTY+MG + E +G+I R ++ LFK I++K
Sbjct: 70 APLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKK 129
Query: 129 KHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGIYTV 188
+F + +LE+YNEE+LDL +R+ K+ I I ED GI V
Sbjct: 130 SDF---------EFTLKVSYLEIYNEEILDLLCPSRE------KAQINIREDPKEGIKIV 174
Query: 189 GVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDADNA 248
G+T +TV + + CL+ G SRT AST MN QSSRSHAIFTI + Q +
Sbjct: 175 GLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK---------- 224
Query: 249 TDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVI 308
+ ++ + +K H VDLAGSER K+T A G+R KEGI+IN GLL LGNVI
Sbjct: 225 ----------KSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVI 274
Query: 309 SALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRA 368
SALGD K+ VPYRDSKLTRLLQDSLGGNS T+MIACVSP+D + ETLNTL+YA+RA
Sbjct: 275 SALGD-DKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRA 333
Query: 369 RNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTG--KRIIDEEGVESINDMFHENA 426
R IKNK +VN D + ++N L+ ++ +LQ+ L++ G I E E++ + +N
Sbjct: 334 RKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQ 393
Query: 427 MLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEI 486
L EN L + + RI ++++QAN +++ ++E+
Sbjct: 394 SLVEENEKLSRGLSEAAGQTAQMLERI--ILTEQAN--------------EKMNAKLEEL 437
Query: 487 EDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLE 546
A L+ + + E L KE +EII ++ +
Sbjct: 438 RQHAACKLDLQKLVETLED-----------------------QELKENVEIICNLQQLIT 474
Query: 547 KLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEE 606
+L ++VA DT E+ E +VE S E S
Sbjct: 475 QL------SDETVACMAAAIDTAVEQ------------EAQVETSPETS----------- 505
Query: 607 EEDDIDGGESSDE-SDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQY 665
SSD + + +A +L + +A+K+ L ++ + +LQ ++ QY
Sbjct: 506 --------RSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQY 557
Query: 666 EEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAA 725
++ + L+ ++ + Q E+++++ L + + + K+ K+LQ + ++ L+
Sbjct: 558 QDNIKELELEVINLQKEKEELVLELQTAK--KDANQAKLSERRRKRLQELEGQIADLKKK 615
Query: 726 QKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQL 785
E ++LLK + E+ + KL Q++ MK +V+LM+QMKE+ EK R + ++++E+ QL
Sbjct: 616 LNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQL 675
Query: 786 KKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAP 845
K+ RKR ++L LE + Q VLRRKTEE A ++++ K R+++
Sbjct: 676 KERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQK-----QREVADKRKE 730
Query: 846 AQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKT 905
Q G A + ++ + V+ +A
Sbjct: 731 TQSRGMEGTAARV---KNWLGNEIEVMVSTEEA--------------------------- 760
Query: 906 ARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEG 965
+R + D++ + ++ D+ +L +++E KL +R + + G+
Sbjct: 761 --------KRHLNDLLEDRKILAQ---DVAQLKEKKESGENPPPKLRRRTFSLTEVRGQV 809
Query: 966 DKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEAR 1025
++ +I +++ESL +++ + I+D Q ++ E + + N T+ EA+
Sbjct: 810 SESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWE-----NIATILEAK 864
Query: 1026 YLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELD 1085
L + + + + Q+ LE LKQ++ + A ++LF AE+ EL
Sbjct: 865 CALKYLIG-------ELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQ 917
Query: 1086 ALL 1088
A L
Sbjct: 918 AEL 920
Score = 51.6 bits (122), Expect = 6e-06
Identities = 80/414 (19%), Positives = 171/414 (41%), Gaps = 33/414 (7%)
Query: 380 DRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRI 439
+R +++ L +I L+ +L E ++ E +++ + E M++ + L +
Sbjct: 596 ERRRKRLQELEGQIADLKKKLNEQSKLLKL-KESTERTVSKLNQEIRMMKNQRVQL---M 651
Query: 440 KAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAV 499
+ M+E + R + Q + + R + E+ + ++ K+ LR K E+ A
Sbjct: 652 RQMKEDAEKFR-QWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAA 710
Query: 500 NENLRKNLT--------RATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRK 551
N+ L+ L R ++ G++ L ++ E + + AK+ L L
Sbjct: 711 NKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLED 770
Query: 552 EKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHED---EEEEEEEEE 608
K + VA ++ +E E R E +VS+ ED ++ E E E
Sbjct: 771 RKILAQDVAQLKEK----KESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETE 826
Query: 609 DDIDGGESSD------ESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLK 662
+ + +D +++SE K ++ + + A+K LI EL +S+ ++ L
Sbjct: 827 MEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKY-LIGELVSSKIQVSKL- 884
Query: 663 KQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRL 722
E L + D Q + + +E+ + + ++ ++++K+ + +LQ+
Sbjct: 885 ---ESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQS 941
Query: 723 QAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQE--KARLT 774
Q A+K+ + + Q K Q + +E + +Q+ E E K +LT
Sbjct: 942 QMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLT 995
Score = 34.7 bits (78), Expect = 0.79
Identities = 49/276 (17%), Positives = 122/276 (44%), Gaps = 35/276 (12%)
Query: 371 IKNKVMVNQDRASQQINALRSE-------ITRLQMELMEYKTGKRIIDE-EGVESINDMF 422
++ +V ++D ++QI +L +E I LQ +L++ ++ R E + +I +
Sbjct: 805 VRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAK 864
Query: 423 HENAMLQTENNNLRVRIKAMQETVDALRSR---ITQLVSDQANHVLARAGEGNEEISNMI 479
L E + ++++ ++ ++ ++ + +++ ++ NH E E+ M
Sbjct: 865 CALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRME 924
Query: 480 HSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIID 539
+ +++ L ++L +S+ + L ++++ + T+ D+E ++ +
Sbjct: 925 QQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQ---------LLSTLKCQDEELEKMRE 975
Query: 540 LAKKDLEKLKRKEKRKKK----SVAGKEDNT--------DTDQEKKEEKGVSERENNELE 587
+ +++ + L+ E K+K VA ++ + D+ E K R +
Sbjct: 976 VCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKF- 1034
Query: 588 VEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE 623
+E+S ++ D + E E +D DG + DE D E
Sbjct: 1035 LEQSMDIEDLKYCSEHSVNEHEDGDGDD--DEGDDE 1068
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 461 bits (1185), Expect = e-129
Identities = 336/1087 (30%), Positives = 543/1087 (49%), Gaps = 184/1087 (16%)
Query: 10 VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCI 69
VRVA+R RP + KE EGC +C S PGE QV +G DK+FT+D+VFD ++QE+++ + +
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAV 69
Query: 70 EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEE-ELGIISRAVKHLFKSIEEK 128
LI+G F+GYNATV AYGQTG+GKTY+MG + E +GII R ++ LFK I++K
Sbjct: 70 APLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEIDKK 129
Query: 129 KHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGIYTV 188
+F + +LE+YNEE+LDL +R+ K+ I I ED GI V
Sbjct: 130 SDF---------EFTLKVSYLEIYNEEILDLLCPSRE------KAQINIREDPKEGIKIV 174
Query: 189 GVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDADNA 248
G+T +TV + + CL+ G SRT AST MN QSSRSHAIFTI + Q +
Sbjct: 175 GLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK---------- 224
Query: 249 TDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVI 308
+ ++ + +K H VDLAGSER K+T A G+R KEGI+IN GLL LGNVI
Sbjct: 225 ----------KSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVI 274
Query: 309 SALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRA 368
SALGD K+ + VPYRDSKLTRLLQDSLGGNS T+MIACVSP+D + ETL+TL+YA+RA
Sbjct: 275 SALGD-DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRA 333
Query: 369 RNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTG--KRIIDEEGVESINDMFHENA 426
R IKNK +VN D + ++N L+ ++ +LQ+ L++ G I+ E E++ + +N
Sbjct: 334 RKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQ 393
Query: 427 MLQTENNNL-RVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKE 485
L EN L R KA +T L I E+++ +++ ++E
Sbjct: 394 SLVEENEKLSRCLSKAAGQTAQMLERIIL-----------------TEQVNEKLNAKLEE 436
Query: 486 IEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDL 545
+ A L+ + + E L KE +EII ++ +
Sbjct: 437 LRQHVACKLDLQKLVETLED-----------------------QELKENVEIICNLQQLI 473
Query: 546 EKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEE 605
+L ++VA DT E+ E +VE S E S
Sbjct: 474 TQL------SDETVACTAAAIDTAVEE------------EAQVETSPETS---------- 505
Query: 606 EEEDDIDGGESSDESDSESDEKANYQADLANITCE----IAIKQKLIDELENSQKRLQTL 661
SD+ + + A +QA ++ E +A+K+ L+ ++ + +LQ +
Sbjct: 506 ------------RSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPI 553
Query: 662 KKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQR 721
+ QY++ + L+ ++ + Q E++++++ L + + + K+ K LQ + ++
Sbjct: 554 QFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQ--AKLSEHRHKLLQELEGQIAD 611
Query: 722 LQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNRE 781
L+ E ++LLK + E+ + KL Q++ MK +V+LM+QMKE+ EK R + ++++E
Sbjct: 612 LKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE 671
Query: 782 IAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSS 841
+ QLK+ RKR ++L LE + Q VLRRKTEE A ++++ K R+++
Sbjct: 672 VIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQK-----QREVTD 726
Query: 842 SDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVF 901
Q G A R ++ + V+ +A
Sbjct: 727 KRKETQSHGKEGIAARV---RNWLGNEIEVMVSTEEA----------------------- 760
Query: 902 ISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKE 961
+R + D++ + ++ D+ +L +++E KL K + +
Sbjct: 761 ------------KRHLNDLLEDRKILAQ---DVVQLKEKKESRENPPPKLRKCTFSLSEV 805
Query: 962 NGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTL 1021
+G+ ++ I +++ESL ++ + I+D Q ++ E + + N T+
Sbjct: 806 HGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWE-----NIATI 860
Query: 1022 TEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELN 1081
EA+ L + + + + + LE L+Q++ + A ++LF +E+
Sbjct: 861 LEAKCALKYLIG-------ELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIE 913
Query: 1082 PELDALL 1088
EL A L
Sbjct: 914 TELQAEL 920
Score = 44.3 bits (103), Expect = 0.001
Identities = 82/418 (19%), Positives = 176/418 (42%), Gaps = 37/418 (8%)
Query: 374 KVMVNQDRASQQ----INALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQ 429
K VNQ + S+ + L +I L+ +L E ++ E +++ + E M++
Sbjct: 586 KKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKL-KESTERTVSKLNQEIWMMK 644
Query: 430 TENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDL 489
+ L ++ M+E + R + Q + + R + E+ + ++ K+ L
Sbjct: 645 NQRVQL---MRQMKEDAEKFR-QWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVL 700
Query: 490 RAKLLESEAVNENLRKNLT--------RATARAPYFSGSSTFSPTILSSDKETIEIIDLA 541
R K E+ A N+ L+ L R ++ G + L ++ E + + A
Sbjct: 701 RRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEA 760
Query: 542 KKDLEKLKRKEKRKKKSVAGKEDNTDTDQE-----KKEEKGVSERENNELEVEE--SQEV 594
K+ L L K + V ++ ++ + +K +SE LE E+ ++++
Sbjct: 761 KRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQI 820
Query: 595 SDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENS 654
E E E + D+ + +++SE K ++ + + A+K LI EL +S
Sbjct: 821 ESLETEMELRSAQIADLQ--QKLLDAESEDRPKQCWENIATILEAKCALKY-LIGELVSS 877
Query: 655 QKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQA 714
+ + L E L + D Q + + +E+ + + ++ ++++K+
Sbjct: 878 KIHVTKL----ENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLY 933
Query: 715 MNKELQRLQAAQKEHARLLKNQSQYEKQL---KKLQQDVMEMKKTKVRLMKQMKEEQE 769
+ +LQ Q A+K+ L K+ S+ E+QL + Q + +E + +Q+ +E E
Sbjct: 934 LVSQLQESQMAEKQ---LEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENE 988
Score = 38.1 bits (87), Expect = 0.072
Identities = 50/277 (18%), Positives = 118/277 (42%), Gaps = 35/277 (12%)
Query: 371 IKNKVMVNQDRASQQINALRSE-------ITRLQMELMEYKTGKRIIDEEGVESINDMFH 423
+ +V+ ++D ++QI +L +E I LQ +L++ ++ R ++ E+I +
Sbjct: 805 VHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDR--PKQCWENIATILE 862
Query: 424 ENAMLQTENNNL---RVRIKAMQETVDALRSR---ITQLVSDQANHVLARAGEGNEEISN 477
L+ L ++ + ++ ++ ++ + +++ ++ NH E E+
Sbjct: 863 AKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVR 922
Query: 478 MIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEI 537
M + +++ L ++L ES+ + L K+ + + T+ D+E ++
Sbjct: 923 MEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQ---------LVSTLQCQDEELEKM 973
Query: 538 IDLAKKDLEKLKRKEKRKKK----SVAGKEDNTDTDQEKKEEKGVS-------ERENNEL 586
++ +++ + L+ E K+K VA ++ + D + E
Sbjct: 974 REVCEQNQQLLQENEIIKQKLILLQVASRQKHLPNDTLLSPDSSFEYIPPKPKPSRVKEK 1033
Query: 587 EVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE 623
+E+S ++ D + E E +D DG SDE D E
Sbjct: 1034 FLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDE 1070
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 368 bits (945), Expect = e-101
Identities = 306/1099 (27%), Positives = 514/1099 (46%), Gaps = 170/1099 (15%)
Query: 6 DESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIY 65
+E V+VAVRIRP L KE + +C V P QV +G+D+ FTFD+VF +S Q+++Y
Sbjct: 2 EEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVY 61
Query: 66 IQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKSI 125
CI+ L+ EGYNATVFAYGQTG+GKTYT+G G ++VE + GII RA++ +F+SI
Sbjct: 62 NTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQSI 121
Query: 126 EEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGI 185
E P+ DF V ++E+Y E++ DL ++ ++ ++ I ED G
Sbjct: 122 SEH---------PSIDFNVKVSYIEVYKEDLRDL------LELETSMKDLHIREDEKGNT 166
Query: 186 YTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDA 245
VG V + E+M L++G +R T +TQMN SSRSHAIFTI +CQ
Sbjct: 167 VIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVH------- 219
Query: 246 DNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALG 305
N +E + +KFHFVDLAGSER+ +TG TGER KE I IN GLLALG
Sbjct: 220 ----KNMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALG 275
Query: 306 NVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYA 365
NVISALGD ++++H+PYRD+K+TRLL+DSLGG+++T+MI CVSPS +F E+LN+LKYA
Sbjct: 276 NVISALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYA 335
Query: 366 NRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHEN 425
NRARNI+NK VN S +I+ + EI L+ L + G +
Sbjct: 336 NRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAG---------------VSQT 380
Query: 426 AMLQTENNNLRVRIKAMQETVDALRSRIT--QLVSDQANHVLARAGEG---NEEISNMIH 480
+ E + RI +++E V L+ Q ++A L + NE+ + +
Sbjct: 381 TQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQ 440
Query: 481 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 540
+ I+++R +L S F G L + + ++ L
Sbjct: 441 EWFNMIQEVRKAVLTS--------------------FRGIG--GTASLEEGPQHVTVLQL 478
Query: 541 AKKDLEKLK-----RKEKRKKKSVAGKEDNTDTDQEKKEEKG--VSERENNELEVEESQE 593
K++L+K + + +K + KE +E KG VS +E ++ ++++
Sbjct: 479 -KRELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEK 537
Query: 594 VSDHEDEEEEEEEEEDDIDGGESS-------DESDSESDEKANYQADLANITCEIAIKQK 646
+ + + ++ EE ++ +S D D+ E+ Y + + +
Sbjct: 538 IIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPY-----TVPFDTHLGHY 592
Query: 647 LIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQL-----ERDQVL-----QNLGSVESY 696
+ +++ T Y + + R L E+D+VL N ES
Sbjct: 593 IYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESE 652
Query: 697 SEEKA----------------------KKVRSEYEKK-LQAMNKELQRLQAAQKEHARLL 733
+EK+ + E +K L+ + ++ LQ +Q+ + + L
Sbjct: 653 GQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKL 712
Query: 734 KNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRD 793
KN + + K+ +++ K K L+K++ + A+ + + ++ +L+ D +
Sbjct: 713 KNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQA- 771
Query: 794 HQLRLLEAQKRNQEVVLR---------------RKTEEVTALRRQVRPMSDKVAGKVTRK 838
++ L+E QK+ QE+ + RK + LR QV + + K+
Sbjct: 772 -KVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASL 830
Query: 839 LSSSDAPAQDTGSSAAAV-------------------ETDASRTGAQQKMR---IPVARV 876
++ A + S + + DA QQK++ + +
Sbjct: 831 SIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQE 890
Query: 877 QALPTPATNGNR-KKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMN 935
+ L A + + +RKG G + + + + L+ V ++ Q+ + +EAD
Sbjct: 891 EGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEAD-- 948
Query: 936 RLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISD--C 993
LK+RE + ++E L +EK EN + + A +N + ++ ++ + +S+
Sbjct: 949 --LKKREAIVSKKEAL--LQEKSHLENKKLRSSQA-LNTDSLKISTRLNLLEQELSEKNV 1003
Query: 994 QANIMQMEEAKEEGETLDV 1012
Q EE + E ++V
Sbjct: 1004 QLQTSTAEEKTKISEQVEV 1022
Score = 116 bits (291), Expect = 2e-25
Identities = 139/561 (24%), Positives = 261/561 (46%), Gaps = 55/561 (9%)
Query: 564 DNTDTDQEKKEEK-GVSERENNELEVEESQ----EVSDHEDEEEEEEEEEDD--IDGGES 616
DN+D ++ + +EK G R + ++ +S E+SD +DE ++ + E +D ID +
Sbjct: 644 DNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQE 703
Query: 617 SDESDSE---SDEKANYQAD--LANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMM 671
S E + + + E+ +A + +T I +K+ LI EL + +++ KQY K+
Sbjct: 704 SQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTK 763
Query: 672 LQHKIRDTQLERDQVLQNLGSVES--YSEEKAK-KVRSEYEKKLQAMNKELQRLQAAQKE 728
L+H ++E + + L +E+ S+ K K++ E+ KK+ A +Q LQ Q++
Sbjct: 764 LEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQD 823
Query: 729 HARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKD 788
+L Q EK+ +L+Q V MK K++L ++++EE EK R + A +K+D
Sbjct: 824 SKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEK-------RKQLDAVIKRD 876
Query: 789 QRK-RDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKV--TRKLSSSDAP 845
Q+K ++ QL K QE L+ K E++ A + R S G + +KL
Sbjct: 877 QQKIKEIQL------KTGQEEGLKPKAEDLDACNLKRRKGS---FGSIDHLQKLDEQKKW 927
Query: 846 AQDTGSSAAAVETDASRTGAQQKMR-IPVARVQALPTPATNGNRKKYQRKGLTGRVFISK 904
+ + A K R V++ +AL ++ KK + +
Sbjct: 928 LDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKI 987
Query: 905 TARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK--EN 962
+ R+ LLE+ +++ +Q T + + ++ +Q E L K +++L KRR + + +N
Sbjct: 988 STRL--NLLEQELSEKNVQLQT--STAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKN 1043
Query: 963 G-----EGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVIN 1017
G E + + + E +E+L A I+Y N+SI + Q ++ GE +V +
Sbjct: 1044 GRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEA-NVLEKLA 1102
Query: 1018 ACTLTEARYLLDHFLSMGIN-----KGLQAAQKEAQIKVLEGRLKQTEITSATQN---QL 1069
+ E R +L + + +N + Q +E ++KVLE E+ SA + Q
Sbjct: 1103 CLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQC 1162
Query: 1070 LFHMLKEKAELNPELDALLGH 1090
+ ++ E ++ LL H
Sbjct: 1163 DRRLTLQQKEHEQKMQLLLHH 1183
Score = 45.8 bits (107), Expect = 3e-04
Identities = 79/432 (18%), Positives = 177/432 (40%), Gaps = 46/432 (10%)
Query: 418 INDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISN 477
++D E EN +L+ I +QE+ + ++ + +L A + E++
Sbjct: 679 LSDTQDETQKSDLENEDLK--IDCLQESQELNLQKLKN-----SERILTEAKQKMRELT- 730
Query: 478 MIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEI 537
IK EDL +L+++ +++ K + + + + + + +E
Sbjct: 731 ---INIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELEN 787
Query: 538 IDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDH 597
DL+ ++ +KE RKK A +++ +K S NE E ++ DH
Sbjct: 788 KDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDH 847
Query: 598 EDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKR 657
++ + + + +E++ A + D Q+ I E++ +
Sbjct: 848 MKYQKIQLQR-------KLREENEKRKQLDAVIKRD-----------QQKIKEIQLKTGQ 889
Query: 658 LQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNK 717
+ LK + E+ L K R LQ L + + +E+ +KV ++ ++L+ +
Sbjct: 890 EEGLKPKAED-LDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQ-RQELEELEA 947
Query: 718 ELQRLQAAQKEHARLLKNQSQYE-KQLKKLQQ------------DVMEMKKTKVRLMKQM 764
+L++ +A + LL+ +S E K+L+ Q +++E + ++ + Q
Sbjct: 948 DLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQT 1007
Query: 765 KEEQEKARLTESRR--NREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRR 822
+EK +++E +E QL+K + D +L+ +E VL + E + AL
Sbjct: 1008 STAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEA 1067
Query: 823 QVRPMSDKVAGK 834
+ ++ + +
Sbjct: 1068 AIEYRNESIQNR 1079
Score = 44.3 bits (103), Expect = 0.001
Identities = 67/317 (21%), Positives = 146/317 (46%), Gaps = 41/317 (12%)
Query: 472 NEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSD 531
+EE+ +++ +E+E+L A L + EA+ L + + S L++D
Sbjct: 929 DEEVEKVLNQR-QELEELEADLKKREAIVSKKEALLQEKS----HLENKKLRSSQALNTD 983
Query: 532 KETIEI-IDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQE----KKEEKGVSERENNEL 586
I ++L +++L EK + + E+ T ++ +KE+ + +R +N
Sbjct: 984 SLKISTRLNLLEQELS-----EKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVD 1038
Query: 587 EVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSES--DEKANYQADLANITC-EIAI 643
E ++ V E+E + EE I+ E++ E +ES + + + +A N++ E +
Sbjct: 1039 EKLKNGRVLSPEEEHVLFQLEEG-IEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANV 1097
Query: 644 KQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQL----------ERDQVLQNLGSV 693
+KL S ++T+ +Y K++ L+ R QL ERD +++ L S
Sbjct: 1098 LEKLACL---SPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESA 1154
Query: 694 ESY----SEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQD 749
+ + + + E+E+K+Q + + +++ +++ YE ++++L++D
Sbjct: 1155 LDHLKLQCDRRLTLQQKEHEQKMQLLLHHFK-----EQDGEGIMETFKTYEDKIQQLEKD 1209
Query: 750 VMEMKKTKVRLMKQMKE 766
+ KKT K++KE
Sbjct: 1210 LYFYKKTSRDHKKKLKE 1226
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 320 bits (821), Expect = 6e-87
Identities = 175/377 (46%), Positives = 237/377 (62%), Gaps = 28/377 (7%)
Query: 2 LGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQ 61
L +E+ VRVA+R+RP L KE + G C V PG +V LG+D+ F F V D+ Q
Sbjct: 8 LPGAEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQ 67
Query: 62 EQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHL 121
E +Y C++ L+E FEG+NATVFAYGQTG+GKTYTMG +++E+E GI+ RA+
Sbjct: 68 EAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEA 127
Query: 122 FKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDS 181
FK I+E + D V+ +LE+Y EE DL ++ + +I++ ED
Sbjct: 128 FKLIDENDLL---------DCLVHVSYLEVYKEEFRDL------LEVGTASRDIQLREDE 172
Query: 182 TGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCP 241
G + GV V E++ L++G +R T +T +N SSRSH +FT+ + Q P
Sbjct: 173 RGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAP 232
Query: 242 QIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 301
S + + L +KFHFVDLAGSER+ +TG+TGER KE I IN L
Sbjct: 233 -------------SRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSL 279
Query: 302 LALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 361
LALGNVISALGD +R +H+PYRDSK+TR+L+DSLGGN++T+MIACVSPS DF ETLNT
Sbjct: 280 LALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNT 339
Query: 362 LKYANRARNIKNKVMVN 378
L YA+RA+NI+N+ VN
Sbjct: 340 LNYASRAQNIRNRATVN 356
Score = 103 bits (256), Expect = 2e-21
Identities = 88/446 (19%), Positives = 213/446 (47%), Gaps = 30/446 (6%)
Query: 628 ANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVL 687
A Q + + I +K++LI EL + K Q L +Q+ +++ L+ + + E +
Sbjct: 704 AQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQ 763
Query: 688 QNLGSVESYSEEKA--KKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKK 745
+ L +E + A + E+ +++ A ++Q L+ ++ RL+ +Q EK+L++
Sbjct: 764 RQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQE 823
Query: 746 LQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRN 805
L+++V M++ + +L ++++EE E+ R +L+ + KR H+++ LE +
Sbjct: 824 LERNVQLMRQQQGQLQRRLREETEQKR-----------RLEAEMSKRQHRVKELELKHEQ 872
Query: 806 QEVVLRRKTEEVTALRRQVRPMSD------KVAGKVTRKLSSSDAPAQDTGSSAAAVETD 859
Q+ +L+ KTEE+ A +R+ R S+ + K+ + D + A+E
Sbjct: 873 QQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEEL 932
Query: 860 ASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTD 919
K +A+ +AL T K+ + + ++R+ + LE+ +++
Sbjct: 933 GEEL---HKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRL--EHLEKELSE 987
Query: 920 IIMQ-----KMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINE 974
Q + + +++ L ++++ L K+R ++ + + + E ++ + ++E
Sbjct: 988 KSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDE 1047
Query: 975 EMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSM 1034
+E+L A I+Y N++I+ C+ +++ + +++ A ++ + +E R LL +
Sbjct: 1048 AIEALDAAIEYKNEAIT-CRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDK 1106
Query: 1035 GINKGLQAAQKEAQIKVLEGRLKQTE 1060
+ + Q++ LE +L++ +
Sbjct: 1107 VVTLREEQHQQQIAFSELEMQLEEQQ 1132
Score = 47.0 bits (110), Expect = 2e-04
Identities = 59/335 (17%), Positives = 144/335 (42%), Gaps = 23/335 (6%)
Query: 426 AMLQTENNNLRVRIKAMQETVDAL--RSRITQLVSDQANHVLARAGEGNEEISNMIHSYI 483
A Q + L + I+ +E + L + Q ++ Q + + + E++ +
Sbjct: 704 AQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQ 763
Query: 484 KEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIE-IIDLAK 542
+++ +L K L+ L++ R A +L K+ E ++ L+
Sbjct: 764 RQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQ--------VLKEKKQATERLVSLSA 815
Query: 543 KDLEKLKRKEK-----RKKKSVAGKEDNTDTDQEKKEEKGVSERENN--ELEVEESQEVS 595
+ ++L+ E+ R+++ + +T+Q+++ E +S+R++ ELE++ Q+
Sbjct: 816 QSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQK 875
Query: 596 DHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQK-LIDEL-EN 653
+ + EE + G + E +K Q + E ++Q+ ++EL E
Sbjct: 876 ILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEE 935
Query: 654 SQKRLQTLKKQ---YEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEK 710
KR L K+ +EK + ++R +Q + +++ +E +E ++K +
Sbjct: 936 LHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQG 995
Query: 711 KLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKK 745
Q+ + + + ++E LLK + + + +L++
Sbjct: 996 SAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQ 1030
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 281 bits (718), Expect = 5e-75
Identities = 243/913 (26%), Positives = 430/913 (47%), Gaps = 128/913 (14%)
Query: 5 PDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQI 64
P E S++V R RP E + G G+ V +G+ K + FD V ++ QEQ+
Sbjct: 4 PAECSIKVMCRFRPLNEAEILRGDKFIPKFK-GDETVVIGQGKPYVFDRVLPPNTTQEQV 62
Query: 65 YIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIVEEELGIISRAVKHLFK 123
Y C +++++ EGYN T+FAYGQT +GKT+TM G D + +GII R +F
Sbjct: 63 YNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQL----MGIIPRIAHDIFD 118
Query: 124 SIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTG 183
I ++ L +F + + E+Y +++ DL D + K+N+ +HED
Sbjct: 119 HI-----YSMDENL---EFHIKVSYFEIYLDKIRDLLDVS--------KTNLAVHEDKNR 162
Query: 184 GIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQI 243
Y G T R V++ E+M + G +R A T MN SSRSH+IF I++ Q V
Sbjct: 163 VPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENV---- 218
Query: 244 DADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLA 303
T+ K L+ K + VDLAGSE++ +TGA G E +IN L A
Sbjct: 219 ----ETEKK-------------LSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSA 261
Query: 304 LGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLK 363
LGNVISAL + +K THVPYRDSK+TR+LQDSLGGN +T ++ C SPS + ET +TL
Sbjct: 262 LGNVISALAEGTK--THVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLM 319
Query: 364 YANRARNIKNKVMVN-----------QDRASQQINALRSEITRLQMELMEYKTGKRIIDE 412
+ RA+ IKN V VN ++ ++ L++ I L+MEL ++ G+ + ++
Sbjct: 320 FGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPED 379
Query: 413 EGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGN 472
E + + + NL E D T ++ + A V + E
Sbjct: 380 EQISA------------KDQKNL--------EPCDN-----TPIIDNIAPVVAGISTEEK 414
Query: 473 EEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNL-----TRATARAPYFSGSSTFSPTI 527
E+ I S ++++D ++ + + E L++ + A+ R Y +
Sbjct: 415 EKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQ 474
Query: 528 LSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEE--KGVSERENNE 585
+ ++ E+ ++ + LE+L +K + V ED T +++ +E + + +
Sbjct: 475 IENEAAKDEVKEVLQA-LEELAVNYDQKSQEV---EDKTRANEQLTDELAQKTTTLTTTQ 530
Query: 586 LEVEESQEVSDHEDEEEEE-----EEEEDDIDGGESSDESDSESDEKANYQADLANITCE 640
E+ + QE+S+H+ + E ++ +I G +++ + +D + +
Sbjct: 531 RELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLY 590
Query: 641 IAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEK 700
I+ + + L N K+L++ + K+ + ++ QL Q + S+ Y +
Sbjct: 591 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM 650
Query: 701 AKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRL 760
+K R + E+ ++++EL +L+A +K H + Q + ++ L +L QD EMKK +
Sbjct: 651 EQK-RRQLEESQDSLSEELAKLRAQEKMHE--VSFQDKEKEHLTRL-QDAEEMKKALEQQ 706
Query: 761 MKQMKE-------------EQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQE 807
M+ +E E+++ + E R + QL++++ D+ +E Q+R +
Sbjct: 707 MESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMK 766
Query: 808 ----VVLRRKTEEVTALRRQVRPMSDKVAGKV-----TRKLSSSDAPAQDTGSSAAAVET 858
++L K E+ R ++ + + V+ ++ RKL D + + ++
Sbjct: 767 LEKLLLLNDKREQA---REDLKGLEETVSRELQTLHNLRKLFVQDLTTR--VKKSVELDN 821
Query: 859 DASRTGAQQKMRI 871
D A QK +I
Sbjct: 822 DDGGGSAAQKQKI 834
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 273 bits (698), Expect = 1e-72
Identities = 244/900 (27%), Positives = 423/900 (47%), Gaps = 130/900 (14%)
Query: 7 ESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYI 66
E +++V R RP E G GE V + K + FD VF + QEQ+Y
Sbjct: 6 ECNIKVMCRFRPLNESEVNRGDKYIAKFQ-GEDTVVIAS-KPYAFDRVFQSSTSQEQVYN 63
Query: 67 QCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIVEEELGIISRAVKHLFKSI 125
C +K+++ EGYN T+FAYGQT +GKT+TM G D E +GII R V+ +F I
Sbjct: 64 DCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD----PEGMGIIPRIVQDIFNYI 119
Query: 126 EEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGI 185
++ L +F + + E+Y +++ DL D + K+N+ +HED
Sbjct: 120 -----YSMDENL---EFHIKVSYFEIYLDKIRDLLDVS--------KTNLSVHEDKNRVP 163
Query: 186 YTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDA 245
Y G T R V + E+M + G +R A T MN SSRSH+IF I+V Q
Sbjct: 164 YVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQE-------- 215
Query: 246 DNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALG 305
+ T+ K L+ K + VDLAGSE++ +TGA G E +IN L ALG
Sbjct: 216 NTQTEQK-------------LSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALG 262
Query: 306 NVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYA 365
NVISAL + S T+VPYRDSK+TR+LQDSLGGN +T ++ C SPS + ET +TL +
Sbjct: 263 NVISALAEGS---TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFG 319
Query: 366 NRARNIKNKVMVNQDRASQQ-----------INALRSEITRLQMELMEYKTGKRI-IDEE 413
RA+ IKN V VN + ++Q LR+ I L+ EL ++ G+ + IDE+
Sbjct: 320 QRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQ 379
Query: 414 -GVESIN-DMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEG 471
E N + F + + N+ I + DA R + + ++ + + +
Sbjct: 380 FDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIA----KLYKQLDDK 435
Query: 472 NEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSD 531
+EEI+ + +E L+ ++L+ E + + R++ A + +S
Sbjct: 436 DEEINQQ----SQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAEND------ASK 485
Query: 532 KETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEES 591
+E E++ + LE+L +K + V K + ++ +K + + + E+++
Sbjct: 486 EEVKEVL----QALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSAT-LASIDAELQKL 540
Query: 592 QEVSDHEDEEEEE--------------EEEEDDIDGGESSDESDSESDEKANYQADLANI 637
+E+++H+ + E +D+ E + D E Y ++ +
Sbjct: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLY---ISKM 597
Query: 638 TCEIAIKQKLIDELENSQ----KRLQTLKK----------QYEEKLMMLQHKIRDTQLER 683
E+ K +LE++Q K+++ +K Q+E K+ L +++ + ++
Sbjct: 598 KSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKK 657
Query: 684 DQVLQNLGS-----VESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQ 738
Q+ +++ + V+ ++EK ++ E+ K+Q N+ Q ++ + H +
Sbjct: 658 RQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSH------RET 711
Query: 739 YEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRL 798
++KQ+ L+ +V + K +L+ ++++ +K L + R E +LK +++ +L
Sbjct: 712 HQKQISSLRDEV----EAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHE 767
Query: 799 LEAQKRNQEVVLR--RKTEEVTALRRQVRPMSDK--VAGKVTRKLSSSDAPAQDTGSSAA 854
L + +E + + EE A Q K V TR S++ + DTG SAA
Sbjct: 768 LTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAA 827
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 272 bits (696), Expect = 2e-72
Identities = 320/1205 (26%), Positives = 527/1205 (43%), Gaps = 164/1205 (13%)
Query: 8 SSVRVAVRIRPQLAKEK-IEGCHIC------TSVTPGE-PQVFLG-----KDKAFTFDYV 54
+SV+VAVR+RP +EK +E I T++T + P+ G + K FT+D+
Sbjct: 2 ASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61
Query: 55 F---DIDS----QQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNI 106
F D S QE ++ +++ FEGYNA VFAYGQTG+GK+YTM G D
Sbjct: 62 FYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS-- 119
Query: 107 VEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDI 166
G+I R + LF I E F+ +LE+YNE V DL
Sbjct: 120 -----GLIPRICEGLFSRINETTR------WDEASFRTEVSYLEIYNERVRDLLRRK--- 165
Query: 167 DAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRS 226
SK N+R+ E G Y ++ V ++ + + G ++RTTA+T MN SSRS
Sbjct: 166 --SSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRS 223
Query: 227 HAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGA 286
HAIFTI Q + ++ + + K H VDLAGSER TGA
Sbjct: 224 HAIFTIKFTQAKFDSEMPCETVS-------------------KIHLVDLAGSERADATGA 264
Query: 287 TGERAKEGISINCGLLALGNVISALGDKS---------KRATHVPYRDSKLTRLLQDSLG 337
TG R KEG +IN L+ LGNVISAL D S K+ VPYRDS LT LL+DSLG
Sbjct: 265 TGVRLKEGGNINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLG 324
Query: 338 GNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQ 397
GNS+TIMIA +SP+D ++ ETL+TL+YANRA+NI NK +N+D + I LR+EI RL+
Sbjct: 325 GNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLK 384
Query: 398 MELMEYKTGKRIIDEEGVESINDMFHENAMLQTE-----NNNLRVRIKAMQETVDALRSR 452
L+ ++D S+ + +N E N ++E ALR
Sbjct: 385 -TLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKE 443
Query: 453 ITQLVSD--------------QANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESE- 497
+V D +L EG + S ++I L LESE
Sbjct: 444 GIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIV-LHGLDLESEH 502
Query: 498 AVNENLRKNLTRATARAPYFS--GSSTFSPTILSSDKETIEIIDLAKKDL-------EKL 548
+ EN+ +T S G T L+ +I L + ++ E
Sbjct: 503 CIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQG----AVILLGRTNMFRFNHPKEAA 558
Query: 549 KRKEKRKKKSVAG-KEDNTDTDQEKKEEKGVS------ERENNELEVEESQEVSDHEDEE 601
K +EKRK ++ TD + ++ V E E + E E E EE
Sbjct: 559 KLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEE 618
Query: 602 EEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTL 661
EE+++ D + E +++ E Q + E ++K++ +EN K L
Sbjct: 619 MEEKQKSDKAELERMQQEVETQRKETEIVQLQIRK--QEESLKRRSF-HIENKLKDLLAE 675
Query: 662 KKQYEEKLMMLQHKI--------RDTQLERDQVLQNLGSVESYSEEKAKK---------V 704
K+++EE+ + Q +I +T L + LQ L E + EKA+K +
Sbjct: 676 KEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRL--KELNNNEKAEKFQIFQELDQL 733
Query: 705 RSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQM 764
+ E +++ + E +RL+ +KE L+ + E+QL++ Q+ + +++ +V+ +++
Sbjct: 734 QKEKDEQYAKLELEKKRLEEQEKEQVMLV---AHLEEQLREKQEMIQLLRRGEVQWVEEE 790
Query: 765 KEEQEKARLT------------ESRRNREIAQLKKDQRKRDHQLRLLEAQKR--NQEVVL 810
K + E R + E E AQL+ + KR ++L+ +K Q+ +L
Sbjct: 791 KRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDIL 850
Query: 811 RRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMR 870
+++ +E + ++ DK ++ K S + ++ R +++ +
Sbjct: 851 KKEVQEEQEILECLKCEHDK-ESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKER-Q 908
Query: 871 IPVARVQALPTPATNGNRK-KYQRKG---LTGRVF-ISKTARMKWQLLERRVTDIIMQKM 925
+ LPT R + +G L ++ + K K + L + + +
Sbjct: 909 LQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQK 968
Query: 926 TISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDY 985
+ E N + +Q E++ K+ +++ + REK +E E + +A + E S
Sbjct: 969 LQATFEFTAN-IARQEEKVRKKEKEILESREKQQREALE--RALARL-ERRHSALQRHST 1024
Query: 986 INDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINK--GLQAA 1043
+ I + + + + E L + L + + L++ + K +
Sbjct: 1025 LGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGV 1084
Query: 1044 QKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENV 1103
QK+ LEG++ + + + + L ++ A +N ++ + LQDL V E
Sbjct: 1085 QKDHH-GTLEGKVASSSLPVSAEKSHLVPLM--DARINAYIEEEVQRRLQDLHRVISEGC 1141
Query: 1104 EDSTD 1108
S D
Sbjct: 1142 STSAD 1146
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 269 bits (688), Expect = 1e-71
Identities = 211/718 (29%), Positives = 342/718 (47%), Gaps = 103/718 (14%)
Query: 9 SVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKA--------FTFDYVFDIDSQ 60
SVRV VR RP KEK V QV + K FTFD V+D +++
Sbjct: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAK 68
Query: 61 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKH 120
Q ++Y + L++ +G+N T+FAYGQTG GKTYTM + E+ G+I + H
Sbjct: 69 QFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTME---GIRGDPEKRGVIPNSFDH 125
Query: 121 LFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHED 180
+F I ++ + V A +LE+Y EE+ RD+ +K + + + E
Sbjct: 126 IFTHISRSQN---------QQYLVRASYLEIYQEEI-------RDLLSKDQTKRLELKER 169
Query: 181 STGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVC 240
G+Y +++ + E+ + +G +R+ +T MN SSRSHAIF I T C
Sbjct: 170 PDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVI----TIEC 225
Query: 241 PQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCG 300
++ D ++ K + VDLAGSER +TGA GER KE IN
Sbjct: 226 SEVGLDGENHIRV--------------GKLNLVDLAGSERQAKTGAQGERLKEATKINLS 271
Query: 301 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 360
L ALGNVISAL D ++TH+PYRDSKLTRLLQDSLGGN++T+M+A V P+ + ETL
Sbjct: 272 LSALGNVISALVDG--KSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLT 329
Query: 361 TLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVE---- 416
TL+YANRA+NIKNK VN+D + + EI RL+ +L + G+R E+ E
Sbjct: 330 TLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGS 389
Query: 417 --SINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEE 474
+ E + E ++ + QE ++ + I + +H L EE
Sbjct: 390 GGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVE------DHSLVA-----EE 438
Query: 475 ISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKET 534
++ K++EDLR + +E + ++ ++ + IL ++
Sbjct: 439 KMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQ- 497
Query: 535 IEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQE-----KKEEKGVSERENNELEVE 589
EI + +++ E ++ E R ++++ KE + QE KK +K S+ + + E+
Sbjct: 498 -EIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIH 556
Query: 590 ESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLID 649
+ QE +H E +E E+ +++ +T E+ +K +I+
Sbjct: 557 DLQE--EHIKERQELEQTQNE--------------------------LTRELKLKHLIIE 588
Query: 650 ELENSQKRLQTLKKQY--EEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVR 705
+++ + + + + EE+ H I T+LE Q+++ S Y ++ R
Sbjct: 589 NFIPLEEKSKIMNRAFFDEEEDHWKLHPI--TRLENQQMMKRPVSAVGYKRPLSQHAR 644
Score = 49.7 bits (117), Expect = 2e-05
Identities = 58/261 (22%), Positives = 114/261 (43%), Gaps = 22/261 (8%)
Query: 534 TIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQE 593
T+ + AK K + E K + ++ + + E++ + R+ E E
Sbjct: 330 TLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGS 389
Query: 594 VSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQ--ADLANITCEIAIKQKLIDEL 651
E+EEEE EE E++ G+ D+ E EK + A + + + K +L+ E
Sbjct: 390 GGGGEEEEEEGEEGEEE---GDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEK 446
Query: 652 ENSQKRLQTLK----------KQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKA 701
E + L+ K K E KL++ I D E+ ++L E +E A
Sbjct: 447 EKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKIL------EQKRQEIA 500
Query: 702 KKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLM 761
++ R E E + Q +++ + L+ ++ ++ L + K+LKKL + +K L
Sbjct: 501 EQKRREREIQQQMESRDEETLE-LKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQ 559
Query: 762 KQMKEEQEKARLTESRRNREI 782
++ +E+++ T++ RE+
Sbjct: 560 EEHIKERQELEQTQNELTREL 580
Score = 33.9 bits (76), Expect = 1.4
Identities = 45/218 (20%), Positives = 99/218 (45%), Gaps = 35/218 (16%)
Query: 651 LENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEK 710
L Q+ + LK Q E++ + R + E+ + G EE+ ++ E +
Sbjct: 355 LREFQEEIARLKAQLEKRSIG-----RRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDD 409
Query: 711 KLQAMNKELQRLQAAQK-----------EHARLLKNQSQYEKQLKKLQQDVMEMKKTKVR 759
K ++ ++L+ ++ E RLLK + + + L++ ++D EM K++
Sbjct: 410 KDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRR-EKDAAEMLGAKIK 468
Query: 760 LMKQ---------MKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVL 810
M+ + E+ ++ E +R +EIA+ K+ +R+ Q+ + R++E +
Sbjct: 469 AMESKLLVGGKNIVDHTNEQQKILEQKR-QEIAEQKRREREIQQQM-----ESRDEETLE 522
Query: 811 RRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQD 848
++T ++L+++V + K K+ KL + A D
Sbjct: 523 LKET--YSSLQQEV-DIKTKKLKKLFSKLQAVKAEIHD 557
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 269 bits (688), Expect = 1e-71
Identities = 195/615 (31%), Positives = 300/615 (48%), Gaps = 76/615 (12%)
Query: 9 SVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKD-------KAFTFDYVFDIDSQQ 61
+V+V VR RP +E+ C +V Q + K FTFD + +D
Sbjct: 5 AVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVT 64
Query: 62 EQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHL 121
EQIY + L+EG EGYN T+FAYGQTG+GK++TM D + GII RA +H+
Sbjct: 65 EQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDP---PSQRGIIPRAFEHV 121
Query: 122 FKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDS 181
F+S++ ++ F V A +LE+YNE+V DL D K K + + E
Sbjct: 122 FESVQCAENTK---------FLVRASYLEIYNEDVRDLLGA----DTKQK---LELKEHP 165
Query: 182 TGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCP 241
G+Y G++ TV++ ++ ++ G +R+ T MN SSRSH+IFTI + + V
Sbjct: 166 EKGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAV-- 223
Query: 242 QIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 301
+ + K + VDLAGSER +TGATGER KE IN L
Sbjct: 224 ----------------DERGKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSL 267
Query: 302 LALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 361
ALGNVISAL D R HVPYRDSKLTRLLQDSLGGN++T+M+AC+SP+D ++ ETL+T
Sbjct: 268 SALGNVISALVDG--RCKHVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLST 325
Query: 362 LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRII---------DE 412
L+YANRA+NI+NK +N+D + + EI +L+ L + + + D
Sbjct: 326 LRYANRAKNIRNKPRINEDPKDALLREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPDP 385
Query: 413 EGVES--------INDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHV 464
VE +D+ E +++ E R+KA + R+R+ + ++ N
Sbjct: 386 VQVEEKLLPQPVIQHDVEAEKQLIREEYEERLARLKADYKAEQESRARLEEDITAMRNSY 445
Query: 465 LARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFS 524
R E + + ++ +A+++ R + P F +
Sbjct: 446 DVRLSTLEENLRKETEAVLQVGVLYKAEVMS--------RAEFASSAEYPPAFQYETVVK 497
Query: 525 PTILSSDKETIEIIDLAKKDLE----KLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSE 580
P + S+ +T+ D++K + +L + E K + G +++ ++ E
Sbjct: 498 PKVFST-TDTLPSDDVSKTQVSSRFAELPKVEPSKSEISLGSSESSSLEETSVSEAFPGP 556
Query: 581 RENNELEVEESQEVS 595
E + +EV E S
Sbjct: 557 EEPSNVEVSMPTEES 571
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 269 bits (688), Expect = 1e-71
Identities = 195/615 (31%), Positives = 300/615 (48%), Gaps = 76/615 (12%)
Query: 9 SVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKD-------KAFTFDYVFDIDSQQ 61
+V+V VR RP +E+ C +V Q + K FTFD + +D
Sbjct: 5 AVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVT 64
Query: 62 EQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHL 121
EQIY + L+EG EGYN T+FAYGQTG+GK++TM D + GII RA +H+
Sbjct: 65 EQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDP---PSQRGIIPRAFEHV 121
Query: 122 FKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDS 181
F+S++ ++ F V A +LE+YNE+V DL D K K + + E
Sbjct: 122 FESVQCAENTK---------FLVRASYLEIYNEDVRDLLGA----DTKQK---LELKEHP 165
Query: 182 TGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCP 241
G+Y G++ TV++ ++ ++ G +R+ T MN SSRSH+IFTI + + V
Sbjct: 166 EKGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAV-- 223
Query: 242 QIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 301
+ + K + VDLAGSER +TGATGER KE IN L
Sbjct: 224 ----------------DERGKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSL 267
Query: 302 LALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 361
ALGNVISAL D R HVPYRDSKLTRLLQDSLGGN++T+M+AC+SP+D ++ ETL+T
Sbjct: 268 SALGNVISALVDG--RCKHVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLST 325
Query: 362 LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRII---------DE 412
L+YANRA+NI+NK +N+D + + EI +L+ L + + + D
Sbjct: 326 LRYANRAKNIRNKPRINEDPKDALLREYQEEIKKLKAILTQQMSPSSLSALLSRQVPPDP 385
Query: 413 EGVES--------INDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHV 464
VE +D+ E +++ E R+KA + R+R+ + ++ N
Sbjct: 386 VQVEEKLLPQPVIQHDVEAEKQLIREEYEERLARLKADYKAEQESRARLEEDITAMRNSY 445
Query: 465 LARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFS 524
R E + + ++ +A+++ R + P F +
Sbjct: 446 DVRLSTLEENLRKETEAVLQVGVLYKAEVMS--------RAEFASSAEYPPAFQYETVVK 497
Query: 525 PTILSSDKETIEIIDLAKKDLE----KLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSE 580
P + S+ +T+ D++K + +L + E K + G +++ ++ E
Sbjct: 498 PKVFST-TDTLPSDDVSKTQVSSRFAELPKVEPSKSEISLGSSESSSLEETSVSEAFPGP 556
Query: 581 RENNELEVEESQEVS 595
E + +EV E S
Sbjct: 557 EEPSNVEVSMPTEES 571
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 266 bits (679), Expect = 2e-70
Identities = 199/615 (32%), Positives = 311/615 (50%), Gaps = 65/615 (10%)
Query: 9 SVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKD-------KAFTFDYVFDIDSQQ 61
+V+V VR RP +EK SV + + K K FTFD VF +S+Q
Sbjct: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQ 73
Query: 62 EQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHL 121
+Y +I+ EGYN T+FAYGQTG GKT+TM V + E GII + H+
Sbjct: 74 LDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTME---GVRAIPELRGIIPNSFAHI 130
Query: 122 FKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDS 181
F HIA G F V +LE+YNEEV RD+ K + + + E
Sbjct: 131 FG------HIAKAEG--DTRFLVRVSYLEIYNEEV-------RDLLGKDQTQRLEVKERP 175
Query: 182 TGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCP 241
G+Y ++ VN +M + + LG +R+ +T MN SSRSHAIFTI T C
Sbjct: 176 DVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTI----TIEC- 230
Query: 242 QIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 301
SE K H VDLAGSER +TGATG+R KE IN L
Sbjct: 231 -------------SEKGIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSL 277
Query: 302 LALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 361
LGNVISAL D ++THVPYR+SKLTRLLQDSLGGNS+T+M A + P+D ++ ET++T
Sbjct: 278 STLGNVISALVDG--KSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETIST 335
Query: 362 LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRI--IDEEGVESIN 419
L+YANRA+NIKNK +N+D + + EI L+ +L E G+ I D G E +
Sbjct: 336 LRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEE---GEEISGSDISGSEEDD 392
Query: 420 DMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMI 479
D E + R + K + + ++++I D+ L + EE N
Sbjct: 393 DEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKI-----DEERKALETKLDMEEEERNKA 447
Query: 480 HSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIID 539
+ E+E LL+++ +++L + L+ A + G +L+ +E ++++
Sbjct: 448 RA---ELEKREKDLLKAQQEHQSLLEKLS-ALEKKVIVGGVD-----LLAKAEEQEKLLE 498
Query: 540 LAKKDLEKLKRKEKRKKKSVAGKE-DNTDTDQEKKEEKGVSERENNELEVEESQEVSDHE 598
+ +LE+ +++ ++ ++ + KE + D +++ + ++ + +L+ + ++
Sbjct: 499 ESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKS 558
Query: 599 DEEEEEEEEEDDIDG 613
+ + ++E + +I+G
Sbjct: 559 EMADLQQEHQREIEG 573
Score = 55.1 bits (131), Expect = 6e-07
Identities = 86/404 (21%), Positives = 160/404 (39%), Gaps = 68/404 (16%)
Query: 444 ETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENL 503
ET+ LR +++A ++ +A + ++ + KEIE+L+ KL E E +
Sbjct: 331 ETISTLR------YANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEI---- 380
Query: 504 RKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKE 563
SGS +S +E + +D EK RK++R KK V+
Sbjct: 381 --------------SGSD------ISGSEEDDDEEGEVGEDGEK--RKKRRGKKKVS--P 416
Query: 564 DNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE 623
D Q K +E E LE + E + E E+ E D+ + +S E
Sbjct: 417 DKMIEMQAKIDE------ERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLE 470
Query: 624 SDEKANYQADLANIT--CEIAIKQKLIDE----LENSQKRLQTLKKQYEEKLMMLQHKIR 677
+ + + + ++KL++E LE +KR + L+++ EEK
Sbjct: 471 KLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEK--------- 521
Query: 678 DTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQS 737
+ ER + + S++ ++ K KK++ + + A ++ Q Q+E LL+N
Sbjct: 522 --EQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIR 579
Query: 738 QYEKQLKK--------LQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQ 789
Q ++L+ + +D EM + V + + E Q K R+ + +
Sbjct: 580 QLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKK 639
Query: 790 RKRDHQLRLLEAQKRNQEVVLRR---KTEEVTALRRQVRPMSDK 830
K ++ L E LR+ K E + + RP + +
Sbjct: 640 EKDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGR 683
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 263 bits (671), Expect = 1e-69
Identities = 280/1052 (26%), Positives = 464/1052 (44%), Gaps = 167/1052 (15%)
Query: 9 SVRVAVRIRPQLAKE-KIEG-CHICTSVTPGEPQVFLG--KDKAFTFDYVFDIDSQQEQI 64
+++V VRIRP + +G ++C SV + K FTFD+V D+D+ QE +
Sbjct: 26 AIKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLHSNPEPKTFTFDHVADVDTTQESV 85
Query: 65 YIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIVEEELGIISRAVKHLFK 123
+ + ++E C GYN T+FAYGQTG+GKT+TM G N G+I R+ ++LF
Sbjct: 86 FATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIPRSFEYLFS 145
Query: 124 SIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTG 183
I+ +K K G F F+E+YNE++ DL D S + + + E
Sbjct: 146 LIDREKE---KAGA-GKSFLCKCSFIEIYNEQIYDLLD--------SASAGLYLREHIKK 193
Query: 184 GIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQI 243
G++ VG + V + +E Q L G +R AST MN +SSRSHA+FTI
Sbjct: 194 GVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTI----------- 242
Query: 244 DADNATDNKIISESAQMNEFETL-TAKFHFVDLAGSERLKRTGATGERAKEGISINCGLL 302
I + NE + T+ + VDLAGSER K T A G R KE +IN L
Sbjct: 243 ---------TIESMEKSNEIVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLS 293
Query: 303 ALGNVISALGDKSK-RATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 361
LG VI+AL D + HV YRDSKLT LL+DSLGGN++T +IA V P R F ETL+T
Sbjct: 294 CLGQVITALVDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLST 353
Query: 362 LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTG----KRIIDEEGVES 417
L +A RA+ IKNK +VN+D ++ L++E+ RL+ +L E +G + + + ++
Sbjct: 354 LNFAQRAKLIKNKAVVNED-TQGNVSQLQAEVKRLKEQLAELASGQTPPESFLTRDKKKT 412
Query: 418 INDMFHENAML-----QTENNNLRVRI-----------KAMQETVDALRSRITQLVSDQA 461
+ + AML + E +L ++ K +Q ++ R Q++ +
Sbjct: 413 NYMEYFQEAMLFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLEK 472
Query: 462 NHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAV------NENLRKNLTRATARAP 515
H +R G EE ++ EI+ LR ++ V N +LR+ R P
Sbjct: 473 LHKESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEP 532
Query: 516 YFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEE 575
+ TI +K EI + K D K ++ A KE + EK +
Sbjct: 533 VKRAQEMDAQTIAKLEKAFSEISGMEKSD------KNQQGFSPKAQKEPCLFANTEKLKA 586
Query: 576 KGV---SERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQA 632
+ + +E N++ E EE +E++ E ES+ +S +KAN
Sbjct: 587 QLLQIQTELNNSKQEYEEFKELTRKRQLEL----------------ESELQSLQKANLNL 630
Query: 633 DLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQ---N 689
+ + K E SQ L K + E L ++ + QL V +
Sbjct: 631 E------NLLEATKACKRQEVSQ-----LNKIHAETLKIITTPTKAYQLHSRPVPKLSPE 679
Query: 690 LGSVESYSEEKAKKVRSEY-------EKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQ 742
+GS S + + + ++ E QA + L+ Q++ + L + E +
Sbjct: 680 MGSFGSLYTQNSSILDNDILNEPVPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHK 739
Query: 743 LKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREI--------AQLKKDQRKRDH 794
KLQQ V +++ QM+E R+ +++ E+ QL++ Q K D
Sbjct: 740 NLKLQQHVDKLEHHST----QMQELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKND- 794
Query: 795 QLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAA 854
L+++ + VVL +E+++++ + K KLS Q
Sbjct: 795 ---FLKSEVHDLRVVLHSADKELSSVKLEYSSFKTN-QEKEFNKLSERHMHVQ------- 843
Query: 855 AVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQL-- 912
+++ R++ N K + K + + MK+++
Sbjct: 844 --------------LQLDNLRLE---------NEKLLESKACLQDSYDNLQEIMKFEIDQ 880
Query: 913 LERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGD--KNVA 970
L R + + + T +++D+N L++ E +R KLS + E+ KEN + K +
Sbjct: 881 LSRNLQNFKKENET---LKSDLNNLMELLEAEKERNNKLSLQFEE-DKENSSKEILKVLE 936
Query: 971 NINEEMESLTANIDYINDSISDCQANIMQMEE 1002
+ +E + TA + + + +++ E+
Sbjct: 937 AVRQEKQKETAKCEQQMAKVQKLEESLLATEK 968
Score = 64.3 bits (155), Expect = 9e-10
Identities = 119/660 (18%), Positives = 277/660 (41%), Gaps = 102/660 (15%)
Query: 383 SQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVR-IKA 441
S+++ ++ +++ LQ +L E + K + ++ V+ + H + +Q ++ R+ K
Sbjct: 716 SEELRTVQEQMSALQAKLDE-EEHKNLKLQQHVDKLE---HHSTQMQELFSSERIDWTKQ 771
Query: 442 MQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNE 501
+E + L QL Q + ++ ++ ++HS KE+ ++ LE +
Sbjct: 772 QEELLSQLNVLEKQLQETQTKNDFLKSEV--HDLRVVLHSADKELSSVK---LEYSSFKT 826
Query: 502 NLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAG 561
N K + + R + + L+ L+ + ++ +S A
Sbjct: 827 NQEKEFNKLSERHMH------------------------VQLQLDNLRLENEKLLESKAC 862
Query: 562 KEDNTDTDQE----------------KKEEKGVSERENNELEVEESQEVSDHEDEEEEEE 605
+D+ D QE KKE + + NN +E+ E+++ +++ + EE
Sbjct: 863 LQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEE 922
Query: 606 EEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQY 665
++E+ E ++ EK Q + A ++A QKL + L ++K + +L+K
Sbjct: 923 DKENS--SKEILKVLEAVRQEK---QKETAKCEQQMAKVQKLEESLLATEKVISSLEKSR 977
Query: 666 EEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAA 725
+ ++ + Q R V + ++++ +E K + +Y L
Sbjct: 978 DSDKKVVADLMNQIQELRTSVCEKTETIDTLKQE-LKDINCKYNSAL------------V 1024
Query: 726 QKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTE--SRRNREIA 783
+E +R+L +KK + D++++K+T +RL + + E+ E+ L E + ++
Sbjct: 1025 DREESRVL---------IKKQEVDILDLKET-LRL-RILSEDIERDMLCEDLAHATEQLN 1073
Query: 784 QLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSD 843
L + +K L+ + + +E +++ ++ + +V ++ K+ + D
Sbjct: 1074 MLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMD 1133
Query: 844 APAQDTGSSAAA--VETDASRTGAQQKMRIPVARVQ--ALPTPATNGNRKKYQRKGLTGR 899
+ A+D S +T ++ Q+ I R +L T N + +
Sbjct: 1134 SAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKN----- 1188
Query: 900 VFISKTARMKWQLLERRVTDIIMQKMTISN--MEADMNRLLKQREELTKRR---EKLSKR 954
++ RMK QL E + Q++ N ++ ++ + +Q+E + ++L
Sbjct: 1189 ---AEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNE 1245
Query: 955 REKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTA 1014
+E+ +KE K V EEM + A+++ + ++ + + ++M + E +TL+ A
Sbjct: 1246 QEESIKERLAKSKIV----EEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKA 1301
Score = 56.6 bits (135), Expect = 2e-07
Identities = 111/539 (20%), Positives = 233/539 (43%), Gaps = 84/539 (15%)
Query: 243 IDADNATDNKIISESAQMNEFETLTAK--FHFVDLAGSERLKRTGATGERAKEGISINCG 300
++A+ +NK+ S Q E + ++K ++ E+ K T ++ + +
Sbjct: 906 LEAEKERNNKL---SLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEES 962
Query: 301 LLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 360
LLA VIS+L +KS RDS +++ D + + C + ET++
Sbjct: 963 LLATEKVISSL-EKS--------RDSD-KKVVADLMNQIQELRTSVC------EKTETID 1006
Query: 361 TLKYANRARNIK-NKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRI-IDEEGVESI 418
TLK + N K N +V+++ + R I + ++++++ K R+ I E +E
Sbjct: 1007 TLKQELKDINCKYNSALVDREES-------RVLIKKQEVDILDLKETLRLRILSEDIE-- 1057
Query: 419 NDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQA-----NHVLARAGEGNE 473
DM E+ TE N+ +A ++ L+S +L +A H L + E E
Sbjct: 1058 RDMLCEDLAHATEQLNMLT--EASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVE 1115
Query: 474 EISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKE 533
+ N + ++++E + ++S A + K P+F T +L + ++
Sbjct: 1116 QKKNEYNFKMRQLEHV----MDSAAEDPQSPKT-------PPHFQ---THLAKLLETQEQ 1161
Query: 534 TIEIIDLAKKDLEKLKRKEK-----------RKKKSVAGKEDNTDTDQEKKEEKGVSERE 582
IE +K LE L K R K+ + E+ Q+ E+ + + +
Sbjct: 1162 EIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQGQ 1221
Query: 583 NNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIA 642
++++ ++ +H D ++ + E+E+ I + + +E +ADL + +
Sbjct: 1222 LDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKI---VEEMLKMKADLEEVQSALY 1278
Query: 643 IKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNL----GSVESYSE 698
K+ + + +R QTL+ + ++ L+ K+ + ER++ Q + VE +E
Sbjct: 1279 NKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVECLAE 1338
Query: 699 EKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTK 757
E K V Q +++++Q + +KE+ RL ++ +KL+ + + +K+ K
Sbjct: 1339 ENGKLVGH------QNLHQKIQYVVRLKKENVRL-------AEETEKLRAENVFLKEKK 1384
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 259 bits (663), Expect = 1e-68
Identities = 239/895 (26%), Positives = 412/895 (46%), Gaps = 129/895 (14%)
Query: 6 DESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIY 65
+E S++V R RP E + G + G+ V +G K + FD VF ++ QEQ+Y
Sbjct: 6 NECSIKVLCRFRPLNQAEILRGDKFIP-IFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVY 63
Query: 66 IQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIVEEELGIISRAVKHLFKS 124
C ++++ GYN T+FAYGQT +GKT+TM G D + +GII R + +F
Sbjct: 64 HACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQL----MGIIPRIARDIFNH 119
Query: 125 IEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGG 184
I ++ L +F + + E+Y +++ DL D T K+N+ +HED
Sbjct: 120 I-----YSMDENL---EFHIKVSYFEIYLDKIRDLLDVT--------KTNLSVHEDKNRV 163
Query: 185 IYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQID 244
+ G T R V++ E++ + G +R A T MN SSRSH+IF I++ Q
Sbjct: 164 PFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQEN------ 217
Query: 245 ADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLAL 304
M + L+ K + VDLAGSE++ +TGA G E +IN L AL
Sbjct: 218 ---------------METEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSAL 262
Query: 305 GNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKY 364
GNVISAL + +K ++VPYRDSK+TR+LQDSLGGN +T M C SPS + ET +TL +
Sbjct: 263 GNVISALAEGTK--SYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMF 320
Query: 365 ANRARNIKNKVMVNQDRASQQ-----------INALRSEITRLQMELMEYKTGKRIIDEE 413
RA+ IKN VN + ++Q A + I +L+ EL ++ G+ + + E
Sbjct: 321 GQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETE 380
Query: 414 GVESINDMFHENAMLQT---ENNNLRVRI--KAMQETVDALRSRITQLVSDQANHVLARA 468
+ +T +N+++ VRI + Q+ + +R R+ + + D+ + +
Sbjct: 381 RLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIR-RLYKQLDDKDDEI---- 435
Query: 469 GEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTIL 528
+ S +I +++ D L+ + NE +++ L+ +
Sbjct: 436 ----NQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSEND------------- 478
Query: 529 SSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEV 588
++ E E++ + LE+L +K + V K ++ +K V+ + E E+
Sbjct: 479 AAKDEVKEVL----QALEELAVNYDQKSQEVEEKSQQNQLLVDELSQK-VATMLSLESEL 533
Query: 589 EESQEVSDHEDEEEEE---------EEEEDDIDGGESS---DESDSESDEKANYQADLAN 636
+ QEVS H+ + E E + GE + S + +E + ++
Sbjct: 534 QRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISK 593
Query: 637 ITCEIAIKQKLIDELENSQ--------------KRLQTLKKQYEEKLMMLQHKIRDTQLE 682
I E+ K +LEN Q Q L Q+E K+ L ++ +L+
Sbjct: 594 IKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELK 653
Query: 683 RDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYE-- 740
+ + + S +S S+E AK E ++ +KE A + + A L+ +S E
Sbjct: 654 KRHLEE---SYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAH 710
Query: 741 -KQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLL 799
+QL +L+ ++ E +KT + ++K+ +K +L + + +LK ++ ++ +L+ L
Sbjct: 711 HRQLARLRDEINEKQKT----IDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQEL 766
Query: 800 E--AQKRNQEVVLRRKTEEVTALRRQVRPMSDK--VAGKVTRKLSSSDAPAQDTG 850
++ Q + EE A Q K V TR S++ +D+G
Sbjct: 767 TFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSG 821
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 251 bits (642), Expect = 3e-66
Identities = 228/780 (29%), Positives = 367/780 (47%), Gaps = 127/780 (16%)
Query: 7 ESSVRVAVRIRPQLAKE--------------KIEGCHICTSVTPGEPQVFLGKDKAFTFD 52
+S V+VAVRIRP +E K+ + T+++ G+ + G+ K F +D
Sbjct: 3 DSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDAR---GQPKVFAYD 59
Query: 53 YVF-DIDSQQEQIY------IQCI-EKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFD 103
+ F +D ++ Y +C+ E +++ F+GYNA +FAYGQTG+GK+YTM GT
Sbjct: 60 HCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTA-- 117
Query: 104 VNIVEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTT 163
++ G+I R LF+ +++++ FKV ++E+YNE+V DL
Sbjct: 118 -----DQPGLIPRLCSGLFERTQKEEN-------EEQSFKVEVSYMEIYNEKVRDL---- 161
Query: 164 RDIDAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQS 223
+D K + +++ E S G Y G++ V + ++ + G SRT A+T MN +S
Sbjct: 162 --LDPKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEES 219
Query: 224 SRSHAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKR 283
SRSHA+F I + T D + T + + K VDLAGSER +
Sbjct: 220 SRSHAVFKITLTHTLY----DVKSGTSGEKVG-------------KLSLVDLAGSERATK 262
Query: 284 TGATGERAKEGISINCGLLALGNVISALGDKS---KRATHVPYRDSKLTRLLQDSLGGNS 340
TGA G+R KEG +IN L LG VISAL D+S + VPYRDS LT LL+DSLGGNS
Sbjct: 263 TGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNS 322
Query: 341 QTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMEL 400
+T M+A VSP+ ++ ETL+TL+YA+RA++I N +VN+D ++ I LR E+ +L+ +L
Sbjct: 323 KTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQL 382
Query: 401 MEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQ 460
+ + K ++ +E + E M T LR + QE L S L S
Sbjct: 383 TKAEAMKSPELKDRLEESEKLIQE--MTVTWEEKLRKTEEIAQERQKQLESLGISLQS-- 438
Query: 461 ANHVLARAGEGNEEISNMIHSYIKEIED--LRAKLLESEAVNENLRKNLTRATARAPYFS 518
S IK +D L A+NE L L T
Sbjct: 439 --------------------SGIKVGDDKCFLVNLNADPALNELLVYYLKEHT-----LI 473
Query: 519 GSSTFSPTILSSDKETIE--IIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEK 576
GS+ L E IID+ + + + +K + V G ++ +
Sbjct: 474 GSANSQDIQLCGMGILPEHCIIDITSEG-QVMLTPQKNTRTFVNGSSVSSPIQLHHGDRI 532
Query: 577 GVSERENNELEVEESQEVSDHEDEEE------EEEEEEDDIDGGESSDESDSESDEKANY 630
L + + ++ ++ EDE++ E E+ D+DG SS+ S S+ NY
Sbjct: 533 LWGNNHFFRLNLPKKKKKAEREDEDQDPSMKNENSSEQLDVDGDSSSEVS---SEVNFNY 589
Query: 631 QADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEE--------KLMMLQHKIRDTQLE 682
+ ++ + K + + Q L +L++Q+EE + +M +H++ +
Sbjct: 590 E------YAQMEVTMKALGSNDPMQSILNSLEQQHEEEKRSALERQRLMYEHELEQLRRR 643
Query: 683 RDQVLQNLGSVESY---SEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQY 739
QN S++ + S +++R E++ +N L RL+ Q A LL ++ Y
Sbjct: 644 LSPEKQNCRSMDRFSFHSPSAQQRLRQWAEEREATLNNSLMRLR-EQIVKANLLVREANY 702
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 244 bits (622), Expect = 7e-64
Identities = 287/1207 (23%), Positives = 502/1207 (41%), Gaps = 209/1207 (17%)
Query: 6 DESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVF-LGKDKAFTFDYVFDIDSQQEQI 64
+E +V V VR+RP ++E+ G ++ + K+F FD VF + + +
Sbjct: 3 EEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNV 62
Query: 65 YIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKS 124
Y + +I+ +GYN T+FAYGQT +GKTYTM E+ LG+I RA+ +F+
Sbjct: 63 YEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGS------EDHLGVIPRAIHDIFQK 116
Query: 125 IEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGG 184
I++ P +F + ++E+YNE + DL T+ K + I ED
Sbjct: 117 IKK---------FPDREFLLRVSYMEIYNETITDLLCGTQ------KMKPLIIREDVNRN 161
Query: 185 IYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQID 244
+Y +T V T ++ + G SR T+MN +SSRSH IF
Sbjct: 162 VYVADLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIF-------------- 207
Query: 245 ADNATDNKIISESAQMN-----EFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINC 299
++I ES + E + + VDLAGSER +TGA G R KEG +IN
Sbjct: 208 -------RMILESREKGEPSNCEGSVKVSHLNLVDLAGSERAAQTGAAGVRLKEGCNINR 260
Query: 300 GLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETL 359
L LG VI L D + + YRDSKLTR+LQ+SLGGN++T +I ++P F ETL
Sbjct: 261 SLFILGQVIKKLSD-GQVGGFINYRDSKLTRILQNSLGGNAKTRIICTITPV--SFDETL 317
Query: 360 NTLKYANRARNIKNKVMVNQ--------DRASQQINALRSEITRLQME------------ 399
L++A+ A+ +KN VN+ R ++I L+ ++ + +E
Sbjct: 318 TALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLA 377
Query: 400 -LMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVS 458
L+E K + + E +E++ M ++ L + R + + + + +
Sbjct: 378 QLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYA 437
Query: 459 DQAN--------------HVLARAGEG----NEEISNMIHSYIKEIE-DLRAKLLESEAV 499
DQ N ++L E ++ SN + + + EIE + KLL E +
Sbjct: 438 DQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDT-LSEIEWNPATKLLNQENI 496
Query: 500 NENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSV 559
L + RA Y + L ++KE +E+ K DL++ + E++ KK
Sbjct: 497 ESELN------SLRADY--DNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKK-- 546
Query: 560 AGKEDNTDTDQEKKEEKGVSEREN--NELEVEESQEVSDHEDEEEEEEEEEDDIDGGESS 617
DQE + +S +N EV ++ + E E+ED I +
Sbjct: 547 ---------DQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEY 597
Query: 618 DESDSESDEKANYQADLANITCEIAIKQKLID--------------------ELENSQKR 657
+S + K + L +I +KQ L D EL+ K
Sbjct: 598 IDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKE 657
Query: 658 LQTLKKQYEEKLMMLQHKIR-------DTQLERDQVLQNLGSVESYSEEKAKK---VRSE 707
L T KQ E + + Q ++ D + E + + S + K K E
Sbjct: 658 LATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLE 717
Query: 708 YEKKLQAMNKELQR---LQAAQKEHARLLKNQSQYEKQLKKLQQDVME-------MKKTK 757
E K+ + KEL + A +E LL ++++L++++ + + K
Sbjct: 718 LEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEK 777
Query: 758 VRLMKQM--KEEQEKARLTESRRNR-EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKT 814
+L ++ KE + + L E + + ++A + + + D + + + + E +
Sbjct: 778 DKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVL 837
Query: 815 EEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDAS--RTGAQQKMRIP 872
EE + +++ +S + AQ SS A++T+ S Q+K R
Sbjct: 838 EENERMNQEIVNLSKE---------------AQKFDSSLGALKTELSYKTQELQEKTREV 882
Query: 873 VARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEA 932
R+ N + ++ L R +T + L+ ++ + + T++ +
Sbjct: 883 QERL----------NEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKD 932
Query: 933 DMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISD 992
D+ +L +E L R++L V N + + + N E ++ I+ + IS+
Sbjct: 933 DLKQL---QESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISE 989
Query: 993 CQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVL 1052
+ + MEE GET D E + + +GI+K K Q L
Sbjct: 990 EVSRNLHMEE--NTGETKD-----------EFQQKM-----VGIDKKQDLEAKNTQ--TL 1029
Query: 1053 EGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAP 1112
+K EI Q + +F +++EK EL L++++ + L + EN+E + +
Sbjct: 1030 TADVKDNEIIE--QQRKIFSLIQEKNELQQMLESVIAEK-EQLKTDLKENIEMTIENQEE 1086
Query: 1113 LNSPGSE 1119
L G E
Sbjct: 1087 LRLLGDE 1093
Score = 87.0 bits (214), Expect = 1e-16
Identities = 165/758 (21%), Positives = 317/758 (41%), Gaps = 87/758 (11%)
Query: 127 EKKHIAIKNGLPA--------PDFKVNAQFLELYNE-EVLDLFDTTRDID--AKSKKSNI 175
EK H ++ +P P+ K ++ E NE E+L TT+D A+ + +
Sbjct: 1272 EKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERL 1331
Query: 176 RIHE---DSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTI 232
R++E +S I ++ + T E ++ +K L T +Q S+S
Sbjct: 1332 RLNEKFQESQEEIKSLTKERDNLKTIKEALE-VKHDQLKEHIRETLAKIQESQSK----- 1385
Query: 233 HVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAK 292
Q + + DN T KI+SE Q ++ + L S+RL+ + + K
Sbjct: 1386 ---QEQSLNMKEKDNET-TKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESH---DEMK 1438
Query: 293 EGISINCGLLALGNVISALGDKSKR------ATHVPYRDSKLTRLLQDSLGGNSQTIMIA 346
L L V+ + D+ K A H+ + ++ L +TI
Sbjct: 1439 SVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEE--LKVAHCCLKEQEETINEL 1496
Query: 347 CVSPSDRDFMETLNTLKYANRARN--IKNKVMVNQDRASQQINALRSEITRLQMELMEYK 404
V+ S+++ ++T++ A N ++NK+ ++ Q SE+ EL ++K
Sbjct: 1497 RVNLSEKE--TEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFK 1554
Query: 405 TGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQE---TVDALRSRITQLVSDQA 461
++ D + M LQ +++ IK +E +AL+ QL +
Sbjct: 1555 EHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQL-KENT 1613
Query: 462 NHVLARAGEGNEE--------ISNMIHSYIKEIEDLRAKLLESEAVN------ENLRKNL 507
++A+ E E+ N + EIE L+ + E++ +N EN+R L
Sbjct: 1614 KEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQF-ETQKLNLENIETENIR--L 1670
Query: 508 TRATARAPYFSGSSTFSPTILSSDKETIEII-DLAKKDLEKLKRKEKRKKKSVAGKEDNT 566
T+ S T L S +ET+++ D K++L + ++ K++ + +
Sbjct: 1671 TQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHL 1730
Query: 567 DTDQEKKEE-KGVSERENNEL-----EVEESQEVSDHEDEEEEEE---------EEEDDI 611
QE ++ +G+ + NE+ ++E S + +D + +EE E+++ I
Sbjct: 1731 KEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETI 1790
Query: 612 DGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMM 671
D + ++D+ +N Q DL N ++ Q+ I EL+ ++ +L TLKK E
Sbjct: 1791 D--KLRGIVSEKTDKLSNMQKDLENSNAKL---QEKIQELKANEHQLITLKKDVNETQKK 1845
Query: 672 LQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKE--LQRLQAAQKEH 729
+ + + +DQ L L +E + A+K+ E+ M + L+R++ K
Sbjct: 1846 VSEMEQLKKQIKDQSL-TLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLE 1904
Query: 730 ARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQ 789
LK Q + K ++ + KT L K+ KE +K R S + +I+ ++KD
Sbjct: 1905 RDQLKESLQ---ETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDL 1961
Query: 790 RKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPM 827
K +L+ + + +E+ L R E+V +++ M
Sbjct: 1962 DKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEM 1999
Score = 77.4 bits (189), Expect = 1e-13
Identities = 145/727 (19%), Positives = 304/727 (41%), Gaps = 109/727 (14%)
Query: 363 KYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGV------- 415
K N N+KN++ N++ + + R E+ + E Y+ K I E V
Sbjct: 1155 KKINEIENLKNELK-NKELTLEHMETERLELAQKLNE--NYEEVKSITKERKVLKELQKS 1211
Query: 416 -ESINDMFH------ENAMLQT--ENNNLRVRIKAMQETVDALRSRITQLVSDQAN-HVL 465
E+ D E LQT E + +K QET+D LR +++ + N L
Sbjct: 1212 FETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDL 1271
Query: 466 ARAGEGNEEISNMIHSY------IKEIEDLRAKLLESEAVNENLRKNLTRATARAPY--- 516
++ +E ++H +KE+ + + + E E + E + AR
Sbjct: 1272 EKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERL 1331
Query: 517 -----FSGSSTFSPTI------LSSDKETIEII-----DLAKKDLEKLKRKEKRKKKSVA 560
F S ++ L + KE +E+ + ++ L K++ + ++++S+
Sbjct: 1332 RLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLN 1391
Query: 561 GKEDNTDTDQEKKEEKGVSERENNELEVEE-----SQEVSDHEDEEEEEEEEEDDIDGGE 615
KE + +T + E + +++ L +E S+ + + DE + +E+DD+
Sbjct: 1392 MKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQ--R 1449
Query: 616 SSDESDSESDE-KANY----------QADLANITCEIAIKQKLIDELE----NSQKRLQT 660
+ SESD+ K N + +L C + +++ I+EL + + T
Sbjct: 1450 LQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEIST 1509
Query: 661 LKKQYEEKLMMLQHKIRDTQLERDQV-LQNLGSVESYSEE--KAKKVRSEYEKKLQAMNK 717
++KQ E LQ+KI++ + +Q ++ + V+ E + K+ R + LQ++
Sbjct: 1510 IQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIES 1569
Query: 718 EL----QRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEK--- 770
++ RLQ +Q+E ++K + + ++ + LQ + ++K+ ++ +MKE QEK
Sbjct: 1570 KMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQ 1629
Query: 771 -ARLTESRRNR----EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEE---VTALRR 822
++T + EI LK+ + L +E + +L EE VT R
Sbjct: 1630 FLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERD 1689
Query: 823 QVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTP 882
+R + + + KV R + T E ++ + +++ + +
Sbjct: 1690 DLRSVEETL--KVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQE-TIDKLRGIVSE 1746
Query: 883 ATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQRE 942
T N +K L K +K I +++ I++M L +Q+E
Sbjct: 1747 KT--NEISNMQKDLEHSNDALKAQDLK-----------IQEELRIAHM-----HLKEQQE 1788
Query: 943 ELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTAN---IDYINDSISDCQANIMQ 999
+ K R +S++ +K+ + + + A + E+++ L AN + + +++ Q + +
Sbjct: 1789 TIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSE 1848
Query: 1000 MEEAKEE 1006
ME+ K++
Sbjct: 1849 MEQLKKQ 1855
Score = 74.3 bits (181), Expect = 9e-13
Identities = 142/693 (20%), Positives = 277/693 (39%), Gaps = 116/693 (16%)
Query: 357 ETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVE 416
E LK ++ K + ++N ++ +EI L+ EL + ++ E +E
Sbjct: 1124 EVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLE 1183
Query: 417 ---SINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNE 473
+N+ + E + E L+ K+ + D LR I ++ + G +
Sbjct: 1184 LAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEA---------TGLQTK 1234
Query: 474 EISNMIHSYIKE----IEDLRAKLLESEAV---NENLRKNLTRATARAPYFSGSSTFSPT 526
E + H ++KE I++LR + E A ++L K+ T+ P P
Sbjct: 1235 EELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPN 1294
Query: 527 I--LSSDKETIEIIDL-----AKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVS 579
+ +S +ET+ ++L KD L R E + + N + ++E K ++
Sbjct: 1295 VKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRL------NEKFQESQEEIKSLT 1348
Query: 580 ERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITC 639
+ +N ++E+ EV H+ +E E I +S E EK N + +
Sbjct: 1349 KERDNLKTIKEALEVK-HDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEME 1407
Query: 640 EIAIKQKLIDELE----NSQKRLQT----LKKQYEEK--LMMLQHKIRDTQLERDQVLQN 689
+ K + +E KRLQ +K +EK L LQ + Q E DQ+ +N
Sbjct: 1408 QFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVL---QSESDQLKEN 1464
Query: 690 LGSVESY---SEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKL 746
+ + + +EE+ K +++ + +N+ R+ ++KE + Q Q E KL
Sbjct: 1465 IKEIVAKHLETEEELKVAHCCLKEQEETINE--LRVNLSEKE-TEISTIQKQLEAINDKL 1521
Query: 747 QQDVMEMKKTKVRL-MKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRN 805
Q + E+ + + + +KQ+ E QEK E+ Q K+ ++ +D L+ +E++
Sbjct: 1522 QNKIQEIYEKEEQFNIKQISEVQEKVN--------ELKQFKEHRKAKDSALQSIESKMLE 1573
Query: 806 QEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGA 865
L+ EE+ + ++ M A +E D +
Sbjct: 1574 LTNRLQESQEEIQIMIKEKEEMKRV--------------------QEALQIERDQLKENT 1613
Query: 866 QQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKM 925
++ VA+++ K+YQ +T +++T ++ E QK+
Sbjct: 1614 KEI----VAKMK-------ESQEKEYQFLKMTA---VNETQEKMCEI-EHLKEQFETQKL 1658
Query: 926 TISNMEADMNRL-------LKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMES 978
+ N+E + RL L++ +TK R+ L E + E + +N+ E+
Sbjct: 1659 NLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENL------RET 1712
Query: 979 LTANIDYINDSISDCQANIMQMEEAKEEGETLD 1011
+T +++ + I+ M KE ET+D
Sbjct: 1713 ITRDLE------KQEELKIVHM-HLKEHQETID 1738
Score = 70.1 bits (170), Expect = 2e-11
Identities = 169/871 (19%), Positives = 356/871 (40%), Gaps = 136/871 (15%)
Query: 313 DKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVS---PSDRDF-------METLNTL 362
+K K + V +++S++ LL++ G ++ + S +D++F M+
Sbjct: 776 EKDKLFSEVVHKESRVQGLLEEI--GKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKY 833
Query: 363 KYANRARNIKNKVMVNQDRASQQ----INALRSEITRLQMELMEYKTGKRIIDEEGVESI 418
K N+ +VN + +Q+ + AL++E++ EL E KT E E +
Sbjct: 834 KMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQE-KT------REVQERL 886
Query: 419 NDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNM 478
N+M L+ ++ L +TV+ ++ IT+ + V E +++ +
Sbjct: 887 NEMEQLKEQLENRDSTL--------QTVEREKTLITEKLQQTLEEVKTLTQE-KDDLKQL 937
Query: 479 IHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEII 538
S E + L++ + ++ +N + ++ L A +E +
Sbjct: 938 QESLQIERDQLKSDIHDTVNMNIDTQEQLRNA------------------------LESL 973
Query: 539 DLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQ----EV 594
++ + LK K + E+NT +++ ++K V + +LE + +Q +V
Sbjct: 974 KQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADV 1033
Query: 595 SDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLA-NITCEIAIKQKLI---DE 650
D+E E++ + + E +S EK + DL NI I +++L DE
Sbjct: 1034 KDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDE 1093
Query: 651 LEN-----SQKRLQTLKKQYE-----EKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEK 700
L+ +Q++ +KK+ E ++L ++ K+++ + + Q L +V+ E
Sbjct: 1094 LKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEM 1153
Query: 701 AKKVRSEYEKKLQAMNKEL-------QRLQAAQK--EHARLLKNQSQYEKQLKKLQQDVM 751
KK+ K + NKEL +RL+ AQK E+ +K+ ++ K LK+LQ+
Sbjct: 1154 QKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQK--- 1210
Query: 752 EMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLR 811
+ + L ++E + T+ LK+ Q D +LR ++K Q + +
Sbjct: 1211 SFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETID-ELRRSVSEKTAQIINTQ 1269
Query: 812 RKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRI 871
+ T L+ ++ + ++ K S Q+T + + ++ + RI
Sbjct: 1270 DLEKSHTKLQEEIPVLHEEQELLPNVKEVSE---TQETMNELELLTEQSTTKDSTTLARI 1326
Query: 872 PVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIM--------- 922
+ R++ + K K I + +K L+ + + +
Sbjct: 1327 EMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQ 1386
Query: 923 -QKMTISNMEADMNRLLKQREELTKRREKLSKRR------EKIVKENGEGDKNVANINEE 975
Q + + + + +++ + E+ + L + K ++E+ + K+VA ++
Sbjct: 1387 EQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDD 1446
Query: 976 M----ESLTANIDYINDSISDCQANIMQMEE--------AKEEGETLDVTAVINACTLTE 1023
+ E L + D + ++I + A ++ EE KE+ ET++ V + TE
Sbjct: 1447 LQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETE 1506
Query: 1024 ARYLLDHFLSMGINKGLQAAQKEAQIKVLE--GRLKQTEITSATQNQLLFHMLKEKAELN 1081
I K L+A + Q K+ E + +Q I ++ Q + LK+ E
Sbjct: 1507 I---------STIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHR 1557
Query: 1082 PELDALLGHALQDLDSVPLE---NVEDSTDE 1109
D+ ALQ ++S LE +++S +E
Sbjct: 1558 KAKDS----ALQSIESKMLELTNRLQESQEE 1584
Score = 47.4 bits (111), Expect = 1e-04
Identities = 136/760 (17%), Positives = 305/760 (40%), Gaps = 105/760 (13%)
Query: 357 ETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVE 416
E + +K + R ++ + + +D+ + + ++ +Q EL KT R++ +E E
Sbjct: 1883 EMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQEL---KTA-RMLSKEHKE 1938
Query: 417 SINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEIS 476
+++ + + + + ++++ K + ++ D L+ +I +L + + + E
Sbjct: 1939 TVDKLREKISEKTIQISDIQ---KDLDKSKDELQKKIQELQKKELQLLRVK------EDV 1989
Query: 477 NMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIE 536
NM H I E+E L+ K E++ NL+ + R F + ++ E I
Sbjct: 1990 NMSHKKINEMEQLK-KQFEAQ--------NLSMQSVRMDNFQLTKKLHESL-----EEIR 2035
Query: 537 IIDLAKKDLEKLKRKEKRKKKS-VAGKEDNTDTDQEK---KEEKGVSERENNELEVEESQ 592
I+ + +L ++K K ++ +A + D++ K EK + L +
Sbjct: 2036 IVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLRE 2095
Query: 593 EVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELE 652
+ S ++ + E +D E + + +++ +Q +L+ + +K L
Sbjct: 2096 KCSRIKELLKRYSEMDDHY---ECLNRLSLDLEKEIEFQKELS-----MRVKANL----- 2142
Query: 653 NSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESY-------SEEKAKKVR 705
L L+ ++ EKL + +E ++++ L V SY E K
Sbjct: 2143 ----SLPYLQTKHIEKLFTANQRC---SMEFHRIMKKLKYVLSYVTKIKEEQHESINKFE 2195
Query: 706 SEYEKKLQAMNKELQRLQAAQKE------HARLLKNQSQYEKQLKKLQQDVMEMK--KTK 757
++ +++ + L ++Q Q++ R LK + ++++ +D E + K
Sbjct: 2196 MDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIK 2255
Query: 758 VRLMKQMKEEQEKARLTESRRNR--EIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKT- 814
+ + +E + E N +I +LK +K + ++ + N+ + + ++
Sbjct: 2256 TEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNEST 2315
Query: 815 --EEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIP 872
EE +A + K + KL + + + +S A V T K
Sbjct: 2316 EFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNP----TTQDNKNPHV 2371
Query: 873 VARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEA 932
+R L T + SK +M+ +L VT+ I+ K+ E+
Sbjct: 2372 TSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKEL---EVTNDIIAKLQAKVHES 2428
Query: 933 DMNRLLKQREELTK------------RREKLSKRREKIVKENGEGDKNVANINEEMESLT 980
N+ L++ +E + +E++ + K+VK + E KN +E+ +
Sbjct: 2429 --NKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATK 2486
Query: 981 ANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGL 1040
A ++Y + I + N+ + ++A++ T+VI+ T + + L+ G G+
Sbjct: 2487 ATVEYQKEVIRLLRENLRRSQQAQD-------TSVISEHTDPQPS---NKPLTCGGGSGI 2536
Query: 1041 QAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAEL 1080
K +K RL++ QN+ ++K+K EL
Sbjct: 2537 VQNTKALILKSEHIRLEKEISKLKQQNE---QLIKQKNEL 2573
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 243 bits (621), Expect = 9e-64
Identities = 199/670 (29%), Positives = 317/670 (47%), Gaps = 108/670 (16%)
Query: 9 SVRVAVRIRPQLAKEKIEGCH-ICT------SVTPGEPQVFLGK-DKAFTFDYVFDIDSQ 60
+++V R RP KE+ G I T VT P+ G+ K FTFD V+D S+
Sbjct: 10 ALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSK 69
Query: 61 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIVEEEL-GIISRAV 118
Q +Y + + LI+ +G+N TVFAYGQTG GKTYTM GT VE EL G+I A
Sbjct: 70 QADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTW-----VEPELRGVIPNAF 124
Query: 119 KHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIH 178
+H+F I ++ + V A +LE+Y EE+ RD+ +K + +
Sbjct: 125 EHIFTHISRSQN---------QQYLVRASYLEIYQEEI-------RDLLSKEPGKRLELK 168
Query: 179 EDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTR 238
E+ G+Y +++ E+ + LG +R ST MN SSRSHAIF I V
Sbjct: 169 ENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITV---- 224
Query: 239 VCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTG------------- 285
C + +D ++ K + VDLAGSER + G
Sbjct: 225 ECSERGSDGQDHIRV--------------GKLNLVDLAGSERQNKAGPNTAGGAATPSSG 270
Query: 286 -----------ATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQD 334
A GER KE IN L ALGNVI+AL R+TH+PYRDSKLTRLLQD
Sbjct: 271 GGGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALA--GNRSTHIPYRDSKLTRLLQD 328
Query: 335 SLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEIT 394
SLGGN++TIM+A + P+ + E+L+TL++ANRA+NIKNK VN+D + + EI
Sbjct: 329 SLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIA 388
Query: 395 RLQMEL-----MEYKTGKRIIDEEGVESINDMFHENAMLQT-------ENNNLRVRIKAM 442
RL+ +L + + ++ + S + E +++ +NNN + +
Sbjct: 389 RLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPI 448
Query: 443 QETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLL-ESEAVNE 501
E+ AL + + +Q + EE I + + + KLL E E + E
Sbjct: 449 LES--ALEKNMENYLQEQKERL--------EEEKAAIQDDRSLVSEEKQKLLEEKEKMLE 498
Query: 502 NLRKNLTRATARAPYFSGSST----FSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKK 557
+LR+ A + + I+ E ++++L ++++ + KR+E+ ++
Sbjct: 499 DLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQ 558
Query: 558 SVAGKEDNT----DTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDG 613
+ +++ T T ++E V ++ +L + ++ +D+ +E D++
Sbjct: 559 EMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLE- 617
Query: 614 GESSDESDSE 623
E+ +E E
Sbjct: 618 -EAQNEQTRE 626
Score = 39.7 bits (91), Expect = 0.025
Identities = 73/305 (23%), Positives = 120/305 (39%), Gaps = 72/305 (23%)
Query: 525 PTILSSDKETI-----EIIDLAKKDLEKL-------KRKEKRKKKSVAGK---------- 562
P + K+T+ E I K LEK +RK R+KK+V+
Sbjct: 369 PRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIE 428
Query: 563 ----EDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSD 618
E+ D + + + + E + LE + + ++ EEE+ D D S+
Sbjct: 429 AWVAEEEDDNNNNHRPPQPILE---SALEKNMENYLQEQKERLEEEKAAIQD-DRSLVSE 484
Query: 619 ESDSESDEKANYQADLAN---ITCEIAIKQKLID-----------ELENSQKRLQTLKKQ 664
E +EK DL T +A K K ++ + N Q+++ LK+Q
Sbjct: 485 EKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQ 544
Query: 665 YEEKLMMLQHKIRDTQLERDQVLQNL----GSVESYSEEKAKKVRSEYEKKLQAMNKEL- 719
+ + +++ + RD+ L S++ E K KK++ Y KLQA+ E+
Sbjct: 545 EIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLY-AKLQAVKAEIQ 603
Query: 720 ----------QRLQAAQKEHARLLKNQSQYEKQLKKL--QQDVMEMKKTKV--RLMKQMK 765
Q L+ AQ E R LK LK L + + +K K+ RL +
Sbjct: 604 DQHDEYIRVRQDLEEAQNEQTRELK--------LKYLIIENFIPPEEKNKIMNRLFLDCE 655
Query: 766 EEQEK 770
EEQ K
Sbjct: 656 EEQWK 660
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 237 bits (605), Expect = 6e-62
Identities = 213/787 (27%), Positives = 379/787 (48%), Gaps = 99/787 (12%)
Query: 6 DESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDID------- 58
+ S V VAVR+RP +EKIE ++ G+ D +++++D+
Sbjct: 355 ENSQVTVAVRVRPFTKREKIEKASQVVFMS-GKEITVEHPDTKQVYNFIYDVSFWSFDEC 413
Query: 59 ----SQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGII 114
+ Q +Y + L+E FEG+N +FAYGQTG+GK+YTM GF EE GII
Sbjct: 414 HPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTM-MGFS-----EEPGII 467
Query: 115 SRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSN 174
R + LF + K+ + + + F E+YNE++ DL +D + + +K
Sbjct: 468 PRFCEDLFSQVARKQTQEVS-------YHIEMSFFEVYNEKIHDLL-VCKDENGQ-RKQP 518
Query: 175 IRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHV 234
+R+ E G Y ++ V++ +++ L+LG R TA+T MN +SSRSH++FT+ +
Sbjct: 519 LRVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVM 578
Query: 235 CQTRVCPQIDADNATDNKIISESAQMNEFE-TLTAKFHFVDLAGSERLKRTGATGERAKE 293
QT+ +E + E + +T++ + +DLAGSER G+R KE
Sbjct: 579 TQTK----------------TEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKE 622
Query: 294 GISINCGLLALGNVISALGDKS-KRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSD 352
G+SIN LL LG VISAL +++ +R+ +PYR+S LT LL++SLGGNS+T MIA +SP+
Sbjct: 623 GVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAA 682
Query: 353 RDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDE 412
+ ETL+TL+YAN+AR I N VN+D ++ I L++EI +L+ + R ID
Sbjct: 683 SNIEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKAA----QRNSRNIDP 738
Query: 413 EGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQA-------NHVL 465
E + + E +LR+++ QE A R+ + +QA L
Sbjct: 739 E----------RYRLCRQEITSLRMKLH-QQERDMAEMQRVWKEKFEQAEKRKLQETKEL 787
Query: 466 ARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSP 525
+AG I + +++ + +L SE + +++ T P S S
Sbjct: 788 QKAG-----IMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSG 842
Query: 526 TILSSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSE--REN 583
+++ D TI+ + + K K + + T + G R N
Sbjct: 843 VLIADDHCTIKNFGGTVSIIPVGEAKTYVNGKHIL---EITVLRHGDRVILGGDHYFRFN 899
Query: 584 NELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADL--ANITCEI 641
+ +EV++ + S + E ++ + +++ +++ +A++ A + +
Sbjct: 900 HPVEVQKGKRPSGRDTPISEGPKDFE-------FAKNELLMAQRSQLEAEIKEAQLKAKE 952
Query: 642 AIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKA 701
+ Q + E +Q+ L + K YE K+ L+ ++R+ + +R ++ + ++ E+
Sbjct: 953 EMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELRE-ESQRKKMQEINNQKANHKIEEL 1011
Query: 702 KKVRSEYEKKLQAMNKELQRLQAAQKE--------HARLLK----NQSQYEKQLKKLQQD 749
+K + E+++ K L+ A K+ HAR+L+ + + K+++ LQQ+
Sbjct: 1012 EKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQN 1071
Query: 750 VMEMKKT 756
KT
Sbjct: 1072 RNNRDKT 1078
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 237 bits (605), Expect = 6e-62
Identities = 178/509 (34%), Positives = 249/509 (48%), Gaps = 82/509 (16%)
Query: 3 GAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFL--------------GKDKA 48
G + + VA+R+RP E EG + + V + ++K+
Sbjct: 5 GDSKDQQLMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKS 64
Query: 49 FTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIV 107
+ FD FD + QE +Y + LIEG GYNATVFAYG TG GKTYTM GT
Sbjct: 65 YLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGT------- 117
Query: 108 EEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDID 167
++E GI + + LF++IEE + +++V+ +LE+YNE + DL + +
Sbjct: 118 DQEPGIYVQTLNDLFRAIEETSNDM--------EYEVSMSYLEIYNEMIRDLLNPSLGY- 168
Query: 168 AKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSH 227
+ + EDS G I G+T + E+MQ L G RT T N SSRSH
Sbjct: 169 -------LELREDSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSH 221
Query: 228 AIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGAT 287
A+ + V Q + I+ E Q + +DLAGSER +T
Sbjct: 222 AVLQVTVRQ----------RSRVKNILQEVRQ--------GRLFMIDLAGSERASQTQNR 263
Query: 288 GERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIAC 347
G+R KEG IN LLALGN I+AL DK ++ YRDSKLTRLL+DSLGGNS+T+MIA
Sbjct: 264 GQRMKEGAHINRSLLALGNCINALSDKGSNK-YINYRDSKLTRLLKDSLGGNSRTVMIAH 322
Query: 348 VSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGK 407
+SP+ F E+ NTL YA RA+NIK +V N S I S I L+ E+ K
Sbjct: 323 ISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLNVSYHIAQYTSIIADLRGEIQRL---K 379
Query: 408 RIIDEE-------GVESINDMFHENAMLQTEN--------NNLRVRI-KAMQETVDA--- 448
R IDE+ G + D+ H A +Q + LR ++ A QE +D
Sbjct: 380 RKIDEQTGRGQARGRQDRGDIRHIQAEVQLHSGQGEKAGMGQLREQLASAFQEQMDVRRR 439
Query: 449 ---LRSRITQLVSDQANHVLARAGEGNEE 474
L +R ++ D + H+L AG +E+
Sbjct: 440 LLELENRAMEVQIDTSRHLLTIAGWKHEK 468
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 236 bits (602), Expect = 1e-61
Identities = 224/812 (27%), Positives = 377/812 (46%), Gaps = 138/812 (16%)
Query: 8 SSVRVAVRIRPQLAKE--KIEGCHI------CTSVTPGEPQVFLGKDKAFTFDYVF---- 55
+SV+VAVR+RP ++E + C I T V P +P+ K+F+FDY +
Sbjct: 4 ASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKE---TPKSFSFDYSYWSHT 60
Query: 56 ---DID-SQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEEL 111
DI+ + Q+Q+Y E++++ FEGYN +FAYGQTGAGK+YTM + +++
Sbjct: 61 SPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQE----KDQQ 116
Query: 112 GIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSK 171
GII + + LF I + + + + V ++E+Y E V DL +
Sbjct: 117 GIIPQLCEDLFSRINDTTNDNMS-------YSVEVSYMEIYCERVRDLLNP-------KN 162
Query: 172 KSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFT 231
K N+R+ E G Y ++ V + +++ + G +RT A+T MN SSRSHA+F
Sbjct: 163 KGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFN 222
Query: 232 IHVCQTRVCPQIDAD-NATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGER 290
I Q R DA+ N T K+ +K VDLAGSER TGA G R
Sbjct: 223 IIFTQKRH----DAETNITTEKV--------------SKISLVDLAGSERADSTGAKGTR 264
Query: 291 AKEGISINCGLLALGNVISALGD---------KSKRATHVPYRDSKLTRLLQDSLGGNSQ 341
KEG +IN L LG VISAL + K K+ +PYRDS LT LL+++LGGNS+
Sbjct: 265 LKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSR 324
Query: 342 TIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELM 401
T M+A +SP+D ++ ETL+TL+YA+RA+ I+ ++N+D ++ I L+ E+TRL
Sbjct: 325 TAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRL----- 379
Query: 402 EYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQA 461
+ ++ +G+ I DM NA++ ++ + + +V +L RI L + +
Sbjct: 380 -----RDLLYAQGLGDITDM--TNALVGMSPSSSLSALSSRAASVSSLHERI--LFAPGS 430
Query: 462 NHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSS 521
+ R E + I+ + ++ +++ A +E EA+ + + FS
Sbjct: 431 EEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKK 490
Query: 522 TFSPTILSSDKETIE-IIDLAKKDLEKLKRK--EKRKKKSVAGKEDNTDTDQEKKEEKGV 578
T L+ D E ++ K + ++ R+ E+R+ ++G + + + +G
Sbjct: 491 TPHLVNLNEDPLMSECLLYYIKDGITRVGREDGERRQDIVLSGHFIKEEHCVFRSDSRGG 550
Query: 579 SE--------------------------RENNELEVEESQEVSDHEDEEEEEEEEEDDID 612
SE R N + + +S + E+ +E E
Sbjct: 551 SEAVVTLEPCEGADTYVNGKKVTEPSILRSGNRIIMGKSHVFRFNHPEQARQERER---- 606
Query: 613 GGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQY----EEK 668
E+ +E + A Q +L ++++ ID + ++RLQ L+ QY EE
Sbjct: 607 --TPCAETPAEPVDWAFAQREL--------LEKQGIDMKQEMEQRLQELEDQYRREREEA 656
Query: 669 LMMLQHKIRDTQLERDQVLQNLGS--------VESYSEEKAKKVRSEYEKKLQAMNK--- 717
+L+ + D + + + + + + S E E++ + E E L A K
Sbjct: 657 TYLLEQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRKWKW 716
Query: 718 -ELQRLQAAQKEHARLLKNQSQYEKQLKKLQQ 748
+ L+ +A LK + +LKK Q
Sbjct: 717 YQFTSLRDLLWGNAIFLKEANAISVELKKKVQ 748
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 236 bits (601), Expect = 2e-61
Identities = 234/871 (26%), Positives = 385/871 (44%), Gaps = 120/871 (13%)
Query: 9 SVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFL--------GKDKAFTFDYVFDIDSQ 60
+++V VR RP E+ H P +V + K +TFD VF ++
Sbjct: 18 NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTK 77
Query: 61 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVN---IVEEE--LGIIS 115
Q +Y + +++ GYN T+FAYGQTG GKT+TM N EE+ GII
Sbjct: 78 QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP 137
Query: 116 RAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNI 175
R + +F+ + + NG +F V LE+YNEE+ DL + + D+ + +
Sbjct: 138 RTLHQIFEKLTD-------NGT---EFSVKVSLLEIYNEELFDLLNPSSDVSER-----L 182
Query: 176 RIHEDSTG--GIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIF--T 231
++ +D G+ G+ TV+ + E+ Q L+ GA RTTA+T MN SSRSH++F T
Sbjct: 183 QMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVT 242
Query: 232 IHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERA 291
IH+ +T + D + + + ++N VDLAGSE + R+GA +RA
Sbjct: 243 IHMKETTI----------DGEELVKIGKLN----------LVDLAGSENIGRSGAVDKRA 282
Query: 292 KEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPS 351
+E +IN LL LG VI+AL + R HVPYR+SKLTR+LQDSLGG ++T +IA +SP+
Sbjct: 283 REAGNINQSLLTLGRVITALVE---RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPA 339
Query: 352 DRDFMETLNTLKYANRARNIKNKVMVNQDRASQQ-INALRSEITRLQMELMEYKTGKRII 410
+ ETL+TL+YA+RA+NI NK VNQ + I EI RL+ +L + +
Sbjct: 340 SLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVY 399
Query: 411 DEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGE 470
E E+ M + + + + L +I A++E + +R+T+L D N +
Sbjct: 400 ISE--ENFRVMSGKLTVQEEQIVELIEKIGAVEEEL----NRVTELFMDNKNEL------ 447
Query: 471 GNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSS 530
++ + DL+ K E E ++L++ + S + + +
Sbjct: 448 --DQCKS----------DLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDA 495
Query: 531 DKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEE 590
+ + ++ KD+ L K RKK DQ E + + + N L
Sbjct: 496 ASKLLNTVEETTKDVSGLHSKLDRKKA----------VDQHNAEAQDIFGKNLNSLFNNM 545
Query: 591 SQEVSDHEDEEEEEEEEEDDIDGGESSDESD-----------SESDEKANYQADLANITC 639
+ + D +++ E + G S S + N ++ I
Sbjct: 546 EELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFN 605
Query: 640 EIAIKQKLIDELEN-SQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSE 698
I +Q L E + Q+ + LK L M+ + L+ + L+++
Sbjct: 606 MILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVA 665
Query: 699 EKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTK- 757
+K + + E + L + L LQ + L+++Q KQ L +D+ +K+T
Sbjct: 666 DKIEDQKKELDGFLSILCNNLHELQ--ENTICSLVESQ----KQCGNLTEDLKTIKQTHS 719
Query: 758 ---VRLMK-------QMKEEQEKARLTESRRNREIAQLKKD-QRKRDHQLRLLEAQKRNQ 806
+LM ++E+ E + S I Q KD K + A
Sbjct: 720 QELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGF 779
Query: 807 EVVLRRKTEEVTALRRQVRPMSDKVAGKVTR 837
LR +E T L + SDK+ G + +
Sbjct: 780 SQELRNFNQEGTKLVEESVKHSDKLNGNLEK 810
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 236 bits (601), Expect = 2e-61
Identities = 165/466 (35%), Positives = 249/466 (53%), Gaps = 59/466 (12%)
Query: 7 ESSVRVAVRIRPQLAKE---------KIEGCHICTSVTPGEPQVFLGKD-KAFTFDYVF- 55
++ V+VAVR+RP +E ++EG P + K K F FDY F
Sbjct: 3 DTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 56 DIDSQQ------EQIYIQCI-EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVE 108
+D +++ +C+ E ++E F+GYNA +FAYGQTG+GK+++M
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH------A 116
Query: 109 EELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDA 168
E+LG+I R LFK I +++ + FKV ++E+YNE+V DL +D
Sbjct: 117 EQLGLIPRLCCALFKRISLEQN-------ESQTFKVEVSYMEIYNEKVRDL------LDP 163
Query: 169 KSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHA 228
K + ++++ E G Y G++ V + ++ + G SRT A+T MN +SSRSHA
Sbjct: 164 KGSRQSLKVREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHA 223
Query: 229 IFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATG 288
+F I + QT D + + +S K VDLAGSER+ +TGA G
Sbjct: 224 VFNIIITQTLY----DLQSGNSGEKVS-------------KVSLVDLAGSERVSKTGAAG 266
Query: 289 ERAKEGISINCGLLALGNVISALGDKSK---RATHVPYRDSKLTRLLQDSLGGNSQTIMI 345
ER KEG +IN L LG VIS+L D++ ++ VPYRDS LT LL+D+LGGNSQT MI
Sbjct: 267 ERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMI 326
Query: 346 ACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKT 405
A +SP+ ++ ETL+TL+YA+RA+ I N +VN+D ++ I LR E+ +L+ +L + +
Sbjct: 327 ATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEA 386
Query: 406 GKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRS 451
K +E +E + E + T LR + QE L S
Sbjct: 387 MKAPELKEKLEESEKLIKE--LTVTWEEKLRKTEEIAQERQRQLES 430
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 236 bits (601), Expect = 2e-61
Identities = 165/466 (35%), Positives = 249/466 (53%), Gaps = 59/466 (12%)
Query: 7 ESSVRVAVRIRPQLAKE---------KIEGCHICTSVTPGEPQVFLGKD-KAFTFDYVF- 55
++ V+VAVR+RP +E ++EG P + K K F FDY F
Sbjct: 3 DTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 56 DIDSQQ------EQIYIQCI-EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVE 108
+D +++ +C+ E ++E F+GYNA +FAYGQTG+GK+++M
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH------A 116
Query: 109 EELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDA 168
E+LG+I R LFK I +++ + FKV ++E+YNE+V DL +D
Sbjct: 117 EQLGLIPRLCCALFKRISLEQN-------ESQTFKVEVSYMEIYNEKVRDL------LDP 163
Query: 169 KSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHA 228
K + ++++ E G Y G++ V + ++ + G SRT A+T MN +SSRSHA
Sbjct: 164 KGSRQSLKVREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHA 223
Query: 229 IFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATG 288
+F I + QT D + + +S K VDLAGSER+ +TGA G
Sbjct: 224 VFNIIITQTLY----DLQSGNSGEKVS-------------KVSLVDLAGSERVSKTGAAG 266
Query: 289 ERAKEGISINCGLLALGNVISALGDKSK---RATHVPYRDSKLTRLLQDSLGGNSQTIMI 345
ER KEG +IN L LG VIS+L D++ ++ VPYRDS LT LL+D+LGGNSQT MI
Sbjct: 267 ERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMI 326
Query: 346 ACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKT 405
A +SP+ ++ ETL+TL+YA+RA+ I N +VN+D ++ I LR E+ +L+ +L + +
Sbjct: 327 ATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEA 386
Query: 406 GKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRS 451
K +E +E + E + T LR + QE L S
Sbjct: 387 MKAPELKEKLEESEKLIKE--LTVTWEEKLRKTEEIAQERQRQLES 430
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 236 bits (601), Expect = 2e-61
Identities = 165/466 (35%), Positives = 249/466 (53%), Gaps = 59/466 (12%)
Query: 7 ESSVRVAVRIRPQLAKE---------KIEGCHICTSVTPGEPQVFLGKD-KAFTFDYVF- 55
++ V+VAVR+RP +E ++EG P + K K F FDY F
Sbjct: 3 DTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 56 DIDSQQ------EQIYIQCI-EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVE 108
+D +++ +C+ E ++E F+GYNA +FAYGQTG+GK+++M
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH------A 116
Query: 109 EELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDA 168
E+LG+I R LFK I +++ + FKV ++E+YNE+V DL +D
Sbjct: 117 EQLGLIPRLCCALFKRISLEQN-------ESQTFKVEVSYMEIYNEKVRDL------LDP 163
Query: 169 KSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHA 228
K + ++++ E G Y G++ V + ++ + G SRT A+T MN +SSRSHA
Sbjct: 164 KGSRQSLKVREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHA 223
Query: 229 IFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATG 288
+F I + QT D + + +S K VDLAGSER+ +TGA G
Sbjct: 224 VFNIIITQTLY----DLQSGNSGEKVS-------------KVSLVDLAGSERVSKTGAAG 266
Query: 289 ERAKEGISINCGLLALGNVISALGDKSK---RATHVPYRDSKLTRLLQDSLGGNSQTIMI 345
ER KEG +IN L LG VIS+L D++ ++ VPYRDS LT LL+D+LGGNSQT MI
Sbjct: 267 ERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMI 326
Query: 346 ACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKT 405
A +SP+ ++ ETL+TL+YA+RA+ I N +VN+D ++ I LR E+ +L+ +L + +
Sbjct: 327 ATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEA 386
Query: 406 GKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRS 451
K +E +E + E + T LR + QE L S
Sbjct: 387 MKAPELKEKLEESEKLIKE--LTVTWEEKLRKTEEIAQERQRQLES 430
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 236 bits (601), Expect = 2e-61
Identities = 165/466 (35%), Positives = 249/466 (53%), Gaps = 59/466 (12%)
Query: 7 ESSVRVAVRIRPQLAKE---------KIEGCHICTSVTPGEPQVFLGKD-KAFTFDYVF- 55
++ V+VAVR+RP +E ++EG P + K K F FDY F
Sbjct: 3 DTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 56 DIDSQQ------EQIYIQCI-EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVE 108
+D +++ +C+ E ++E F+GYNA +FAYGQTG+GK+++M
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH------A 116
Query: 109 EELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDA 168
E+LG+I R LFK I +++ + FKV ++E+YNE+V DL +D
Sbjct: 117 EQLGLIPRLCCALFKRISLEQN-------ESQTFKVEVSYMEIYNEKVRDL------LDP 163
Query: 169 KSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHA 228
K + ++++ E G Y G++ V + ++ + G SRT A+T MN +SSRSHA
Sbjct: 164 KGSRQSLKVREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHA 223
Query: 229 IFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATG 288
+F I + QT D + + +S K VDLAGSER+ +TGA G
Sbjct: 224 VFNIIITQTLY----DLQSGNSGEKVS-------------KVSLVDLAGSERVSKTGAAG 266
Query: 289 ERAKEGISINCGLLALGNVISALGDKSK---RATHVPYRDSKLTRLLQDSLGGNSQTIMI 345
ER KEG +IN L LG VIS+L D++ ++ VPYRDS LT LL+D+LGGNSQT MI
Sbjct: 267 ERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMI 326
Query: 346 ACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKT 405
A +SP+ ++ ETL+TL+YA+RA+ I N +VN+D ++ I LR E+ +L+ +L + +
Sbjct: 327 ATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEA 386
Query: 406 GKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRS 451
K +E +E + E + T LR + QE L S
Sbjct: 387 MKAPELKEKLEESEKLIKE--LTVTWEEKLRKTEEIAQERQRQLES 430
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 231 bits (590), Expect = 3e-60
Identities = 156/433 (36%), Positives = 217/433 (50%), Gaps = 71/433 (16%)
Query: 10 VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVF-----------------------LGKD 46
++V VR+RP+ KEK G H V VF KD
Sbjct: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
Query: 47 KAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNI 106
F FD VFD S Q +++ + ++ GYN TV AYG TGAGKT+TM D
Sbjct: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSAD--- 128
Query: 107 VEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDI 166
E G++ + HL+K ++E K I + +LE+YNE++ DL +
Sbjct: 129 ---EPGVMYLTMLHLYKCMDEIKEEKICS--------TAVSYLEVYNEQIRDLLVNS--- 174
Query: 167 DAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRS 226
+ + ED+ G+ G+T + E++ L G +RT T MN SSRS
Sbjct: 175 ------GPLAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRS 228
Query: 227 HAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGA 286
HA+F I++ Q ++A +N+ AK +DLAGSER +GA
Sbjct: 229 HAVFQIYLRQQ-----------------DKTASINQ-NVRIAKMSLIDLAGSERASTSGA 270
Query: 287 TGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIA 346
G R EG +IN LLALGNVI+AL D ++ H+PYR+SKLTRLL+DSLGGN QTIMIA
Sbjct: 271 KGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIA 330
Query: 347 CVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQI-------NALRSEITRLQME 399
VSPS + +T NTLKYANRA++IK+ + N + I N ++EI L+ +
Sbjct: 331 AVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEK 390
Query: 400 LMEYKTGKRIIDE 412
L Y+ K +E
Sbjct: 391 LKAYEEQKAFTNE 403
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 227 bits (579), Expect = 6e-59
Identities = 231/850 (27%), Positives = 384/850 (45%), Gaps = 134/850 (15%)
Query: 8 SSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKD-----KAFTFDYVF------- 55
+SV+VAVR+RP ++E + + + K+ K+F+FDY +
Sbjct: 4 ASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPE 63
Query: 56 -DIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGII 114
+ Q ++Y ++++ FEGYN +FAYGQTGAGK+YTM + E + GII
Sbjct: 64 DPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQE----ESQAGII 119
Query: 115 SRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSN 174
+ + LF+ I + N + V ++E+Y E V DL + K N
Sbjct: 120 PQLCEELFEKIND-------NCNEEMSYSVEVSYMEIYCERVRDLLNP-------KNKGN 165
Query: 175 IRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHV 234
+R+ E G Y ++ V + +++ + G +RT A+T MN SSRSHA+FTI
Sbjct: 166 LRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTI-- 223
Query: 235 CQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEG 294
V Q DN T N +K VDLAGSER TGA G R KEG
Sbjct: 224 ----VFTQKKHDNET-----------NLSTEKVSKISLVDLAGSERADSTGAKGTRLKEG 268
Query: 295 ISINCGLLALGNVISALGD---KSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPS 351
+IN L LG VISAL + K K+ +PYRDS LT LL+++LGGNS+T M+A +SP+
Sbjct: 269 ANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPA 328
Query: 352 DRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIID 411
D ++ ETL+TL+YA+RA+ IK ++N+D ++ + L+ E+TRL K ++
Sbjct: 329 DINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRL----------KDLLR 378
Query: 412 EEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEG 471
+G+ I D L + ++ + + +V +++ RI + + + R E
Sbjct: 379 AQGLGDIIDT--SMGSLTSSPSSCSLSSQVGLTSVTSIQERI--MSTPGGEEAIERLKES 434
Query: 472 NEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSD 531
+ I+ + ++ +++ A +E EA+ + + FS T L+ D
Sbjct: 435 EKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNED 494
Query: 532 KETIE---------IIDLAKKDLEKLKR--------KEK----RKKKSVAGKEDNTDTDQ 570
E I + + D E+ + KE+ R ++S +G+ T
Sbjct: 495 PLMSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNSGEVIVTLEPC 554
Query: 571 EKKEE----KGVSE----RENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDS 622
E+ E K VS+ R N + + ++ + E+ E E+ S E+ S
Sbjct: 555 ERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFRFNHPEQARAEREK------TPSAETPS 608
Query: 623 ESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTL----KKQYEEKLMMLQHKIRD 678
E + Q +L ++++ ID + +KRLQ + KK+ EE ++L+ + D
Sbjct: 609 EPVDWTFAQREL--------LEKQGIDMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLD 660
Query: 679 TQLERDQVLQNLGSVESYSEEKAKKVRSEYEK----KLQAMNKELQRLQAAQKEHARLLK 734
+ S + EE K + S EK KLQ + K+ L ++ K+ +
Sbjct: 661 ADSDSGD-----DSDKRSCEESWKLITSLREKLPPSKLQTIVKKC-GLPSSGKKREPIKM 714
Query: 735 NQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQL--------- 785
Q ++L K + + K++ +K++ E SR+ E +
Sbjct: 715 YQIPQRRRLSK-DSKWVTISDLKIQAVKEICYEVALNDFRHSRQEIEALAIVKMKELCAM 773
Query: 786 --KKDQRKRD 793
KKD +RD
Sbjct: 774 YGKKDPNERD 783
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 227 bits (579), Expect = 6e-59
Identities = 211/751 (28%), Positives = 348/751 (46%), Gaps = 113/751 (15%)
Query: 8 SSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKD-----KAFTFDYVF------- 55
+SV+VAVR+RP ++E + + + K+ K+F+FDY +
Sbjct: 4 ASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPE 63
Query: 56 -DIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGII 114
+ Q ++Y ++++ FEGYN +FAYGQTGAGK+YTM + E + GII
Sbjct: 64 DPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQE----ESQAGII 119
Query: 115 SRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSN 174
+ + LF+ I + N + V ++E+Y E V DL + K N
Sbjct: 120 PQLCEELFEKIND-------NCNEEMSYSVEVSYMEIYCERVRDLLNP-------KNKGN 165
Query: 175 IRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHV 234
+R+ E G Y ++ V + +++ + G +RT A+T MN SSRSHA+FTI
Sbjct: 166 LRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTI-- 223
Query: 235 CQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEG 294
V Q DN T N +K VDLAGSER TGA G R KEG
Sbjct: 224 ----VFTQKKHDNET-----------NLSTEKVSKISLVDLAGSERADSTGAKGTRLKEG 268
Query: 295 ISINCGLLALGNVISALGD---KSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPS 351
+IN L LG VISAL + K K+ +PYRDS LT LL+++LGGNS+T M+A +SP+
Sbjct: 269 ANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPA 328
Query: 352 DRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIID 411
D ++ ETL+TL+YA+RA+ IK ++N+D ++ + L+ E+TRL K ++
Sbjct: 329 DINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRL----------KDLLR 378
Query: 412 EEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEG 471
+G+ I D L + ++ + + +V +++ RI + + + R E
Sbjct: 379 AQGLGDIIDT--SMGSLTSSPSSCSLSSQVGLTSVTSIQERI--MSTPGGEEAIERLKES 434
Query: 472 NEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSD 531
+ I+ + ++ +++ A +E EA+ + + FS T L+ D
Sbjct: 435 EKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNED 494
Query: 532 KETIE---------IIDLAKKDLEKLKR--------KEK----RKKKSVAGKEDNTDTDQ 570
E I + + D E+ + KE+ R ++S +G+ T
Sbjct: 495 PLMSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNSGEVIVTLEPC 554
Query: 571 EKKEE----KGVSE----RENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDS 622
E+ E K VS+ R N + + ++ + E+ E E+ S E+ S
Sbjct: 555 ERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFRFNHPEQARAEREK------TPSAETPS 608
Query: 623 ESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTL----KKQYEEKLMMLQHKIRD 678
E + Q +L ++++ ID + +KRLQ + KK+ EE ++L+ + D
Sbjct: 609 EPVDWTFAQREL--------LEKQGIDMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLD 660
Query: 679 TQLERDQVLQNLGSVESYSEEKAKKVRSEYE 709
+ + Q LQ S + E ++ E E
Sbjct: 661 YE-SKLQALQKQVETRSLAAETTEEEEEEEE 690
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 219 bits (557), Expect = 2e-56
Identities = 150/410 (36%), Positives = 223/410 (54%), Gaps = 51/410 (12%)
Query: 8 SSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKD-----KAFTFDYVF-----DI 57
+SV+VAVR+RP A+E + S+ + K K+FTFDY +
Sbjct: 4 ASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTE 63
Query: 58 DSQ---QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGII 114
D Q Q+Q+Y E+++ FEGYN +FAYGQTGAGK+YTM + + GI+
Sbjct: 64 DPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPG----QQGIV 119
Query: 115 SRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSN 174
+ + LF + E + + + V ++E+Y E V DL ++ KS+ S
Sbjct: 120 PQLCEDLFSRVSENQSAQLS-------YSVEVSYMEIYCERVRDL------LNPKSRGS- 165
Query: 175 IRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHV 234
+R+ E G Y ++ V + +++ + G +RT A+T MN SSRSHA+FTI
Sbjct: 166 LRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVF 225
Query: 235 CQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEG 294
Q C D D++ +S K VDLAGSER +GA G R KEG
Sbjct: 226 TQR--CH--DQLTGLDSEKVS-------------KISLVDLAGSERADSSGARGMRLKEG 268
Query: 295 ISINCGLLALGNVISALGD---KSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPS 351
+IN L LG VISAL D K +++ +PYRDS LT LL+++LGGNS+T MIA +SP+
Sbjct: 269 ANINKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPA 328
Query: 352 DRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELM 401
D ++ ETL+TL+YA+R + I+ ++N+D ++ I L+ E+ RL+ LM
Sbjct: 329 DINYEETLSTLRYADRTKQIRCNAIINEDPNARLIRELQEEVARLRELLM 378
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,074,538
Number of Sequences: 37866
Number of extensions: 2802012
Number of successful extensions: 55861
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1015
Number of HSP's successfully gapped in prelim test: 1741
Number of HSP's that attempted gapping in prelim test: 18005
Number of HSP's gapped (non-prelim): 16938
length of query: 1661
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1545
effective length of database: 13,855,062
effective search space: 21406070790
effective search space used: 21406070790
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.