Search of human proteins with 38505220

Search of human proteins with 38505220

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38505220 acyl-CoA synthetase medium-chain family member 5
[Homo sapiens]
         (579 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho...  1193   0.0  
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H...   746   0.0  
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s...   735   0.0  
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H...   667   0.0  
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...   649   0.0  
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [...   646   0.0  
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [...   646   0.0  
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC...   597   e-170
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC...   597   e-170
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s...   481   e-136
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...   420   e-117
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo...   179   5e-45
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso...   179   6e-45
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom...   169   8e-42
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom...   166   5e-41
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]       129   1e-29
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]       129   1e-29
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]       125   1e-28
gi|38524616 solute carrier family 27, member 1 [Homo sapiens]          92   2e-18
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           71   3e-12
gi|40807357 solute carrier family 27 (fatty acid transporter), m...    69   1e-11
gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens]                  63   8e-10
gi|62865631 solute carrier family 27 (fatty acid transporter), m...    62   1e-09
gi|13325055 solute carrier family 27 (fatty acid transporter), m...    62   1e-09
gi|227499619 solute carrier family 27 (fatty acid transporter), ...    59   2e-08
gi|13325057 solute carrier family 27 (fatty acid transporter), m...    56   1e-07
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]     52   2e-06
gi|209529739 hypothetical protein LOC100132247 [Homo sapiens]          51   3e-06
gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-ch...    51   3e-06
gi|239745482 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06

>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
           sapiens]
          Length = 579

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 579/579 (100%), Positives = 579/579 (100%)

Query: 1   MRPWLRHLVLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQLVPEYFNFAHDVL 60
           MRPWLRHLVLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQLVPEYFNFAHDVL
Sbjct: 1   MRPWLRHLVLQALRNSRAFCGSHGKPAPLPVPQKIVATWEAISLGRQLVPEYFNFAHDVL 60

Query: 61  DVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMML 120
           DVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMML
Sbjct: 61  DVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMML 120

Query: 121 VLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAIS 180
           VLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAIS
Sbjct: 121 VLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAIS 180

Query: 181 AECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMV 240
           AECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMV
Sbjct: 181 AECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMV 240

Query: 241 EHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRV 300
           EHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRV
Sbjct: 241 EHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRV 300

Query: 301 DAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKH 360
           DAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKH
Sbjct: 301 DAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKH 360

Query: 361 QTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNVA 420
           QTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNVA
Sbjct: 361 QTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNVA 420

Query: 421 VRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSSY 480
           VRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSSY
Sbjct: 421 VRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSSY 480

Query: 481 RIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHV 540
           RIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHV
Sbjct: 481 RIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHV 540

Query: 541 KRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWGK 579
           KRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWGK
Sbjct: 541 KRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWGK 579


>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
           sapiens]
          Length = 580

 Score =  746 bits (1925), Expect = 0.0
 Identities = 349/543 (64%), Positives = 435/543 (80%), Gaps = 1/543 (0%)

Query: 36  VATWEAISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEEL 95
           +A +EAI+   + +P+ FNFA DVLD WS+ E+ G RP NPA WWVNG G E+KWSF EL
Sbjct: 35  LADFEAINRCNRPLPKNFNFAADVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFREL 94

Query: 96  GKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLK 155
           G  SRKAANVL   CGLQ GDR+ ++LPR+PEWWLV+VAC+RTG + +PG  QLT KD+ 
Sbjct: 95  GSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDIL 154

Query: 156 YRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHN 215
           YRL+AS+AK I+ S+ +AP V++I  ECP L+TKLLVS  S  GWL+F+EL + AS EH+
Sbjct: 155 YRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHS 214

Query: 216 CMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGW 275
           C+ T S++P+ IYFTSGTTG PKM +HSQSS G+GF   GR W+ L  SDI WN +DTGW
Sbjct: 215 CVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGW 274

Query: 276 VKAA-WTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTR 334
           VKAA  ++FS+W  G+C+FVH + + D    L+TL+ +PITTLC  PT++R+LVQ+DL R
Sbjct: 275 VKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQKDLKR 334

Query: 335 YQFQSLRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGK 394
           Y+F+SLRHCLTGGE LNP+V E+W+ QTG+ELYEGYGQ+E  +ICAN KG +IK GSMGK
Sbjct: 335 YKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGK 394

Query: 395 ASPPYDVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITG 454
              PYDVQI+D+ GNVLPPG+EG +A+R++PTRPFCFF+ Y+DNP+KTAA+ +GDFY+TG
Sbjct: 395 GMLPYDVQIIDENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYVTG 454

Query: 455 DRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVV 514
           DR  MD DGYFWF+GR DDVI SS YRIGP EVESAL EHPAV+ESAVVSSPD IRGEVV
Sbjct: 455 DRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVV 514

Query: 515 KAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRS 574
           KAF+VL   + S++PE LT ELQ+HVK+ TAPYKYPRKV FV ELPKT++GKI+R+ LR 
Sbjct: 515 KAFVVLAAPFKSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRD 574

Query: 575 QEW 577
           QEW
Sbjct: 575 QEW 577


>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
           sapiens]
          Length = 586

 Score =  735 bits (1897), Expect = 0.0
 Identities = 331/530 (62%), Positives = 426/530 (80%), Gaps = 1/530 (0%)

Query: 49  VPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGG 108
           +PEYFNFA DVLD W+  E+AG +P NPAFWW+N  G E++WSFEELG  SRK AN+L  
Sbjct: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113

Query: 109 ACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIIT 168
           AC LQ GDR++L+LPR+PEWWL +VAC+RTGTV+IPG TQLT+KD+ YRLQ+S+A  IIT
Sbjct: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173

Query: 169 SDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIY 228
           +D LAP VDA++++C +L +KL+VS++SR GW N +EL++ AS  H C++TK  + +AI+
Sbjct: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233

Query: 229 FTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWT-LFSAWP 287
           FTSGT+G PKM  H+ SS+GLG   +GR W+ LT SD+ WNT+DTGW K+AW+ +FS W 
Sbjct: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293

Query: 288 NGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGG 347
            G+C+F H LPR +   IL TLSK+PIT  C  PT++R+LVQ D+T Y+F+SL+HC++ G
Sbjct: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353

Query: 348 EALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDE 407
           E + PDV EKW+++TG+++YEGYGQ+ETV+IC N KGMKIK GSMGK SP +DV+IVD  
Sbjct: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413

Query: 408 GNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWF 467
           GNVLPPG+EG++ +++ P RPF  F  Y+DNP KTA++ +G+FYITGDR  MDKDGYFWF
Sbjct: 414 GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWF 473

Query: 468 MGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSH 527
           + R DDVI SS YRIGP EVE+AL EHP+V ESAVVSSPDPIRGEVVKAF+VL P Y SH
Sbjct: 474 VARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSH 533

Query: 528 DPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEW 577
           D E L +E+QEHVK+ TAPYKYPRKV F+ ELPKT+SGK +R++LR +EW
Sbjct: 534 DQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEW 583


>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
           sapiens]
          Length = 577

 Score =  667 bits (1721), Expect = 0.0
 Identities = 325/579 (56%), Positives = 415/579 (71%), Gaps = 12/579 (2%)

Query: 10  LQALRNSRAFCGSHGK-----PAPLPVPQKIVATWEAISLGRQLVPEYFNFAHDVLDVWS 64
           +Q L   R   G H       PAP  +  + ++ + A       VPE FNFA  VLD W+
Sbjct: 1   MQWLMRFRTLWGIHKSFHNIHPAPSQLRCRSLSEFGAPRWNDYEVPEEFNFASYVLDYWA 60

Query: 65  RLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPR 124
           + E+ G R PNPAFWWVNG G E+KWSF E+G  +R+ ANV    CGLQ GD + L+LPR
Sbjct: 61  QKEKEGKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHLALMLPR 120

Query: 125 LPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAISAECP 184
           +PEWWLV+V CMRTG + IP    L  KD+ YRLQ S+AK I+T D+LA  VD+I+++CP
Sbjct: 121 VPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDSIASQCP 180

Query: 185 SLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQ 244
           SL+TKLLVSD SR GWL+FR L++ AS EH C+++K+ DP+ I+FTSGTTG PKM +HS 
Sbjct: 181 SLKTKLLVSDHSREGWLDFRSLVKSASPEHTCVKSKTLDPMVIFFTSGTTGFPKMAKHS- 239

Query: 245 SSYGLGFVAS---GRRWVALTESDIFWNTTDTGWVKAA-WTLFSAWPNGSCIFVHELPRV 300
             +GL    S    R+  +L  SD+ W  +D+GW+ A  WTL   W  G  +F+H LP+ 
Sbjct: 240 --HGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTAGCTVFIHHLPQF 297

Query: 301 DAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKH 360
           D KVI+ TL K+PI     V +I+R+++Q+D T  +F +L HC TGGE + P  +E+WK 
Sbjct: 298 DTKVIIQTLLKYPINHFWGVSSIYRMILQQDFTSIRFPALEHCYTGGEVVLPKDQEEWKR 357

Query: 361 QTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNVA 420
           +TG+ LYE YGQSET +ICA   GMKIK G MGKA+PPYDVQ++DD+G++LPP  EGN+ 
Sbjct: 358 RTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVIDDKGSILPPNTEGNIG 417

Query: 421 VRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSSY 480
           +RI+P RP   F CY  +PEKTA  E GDFY TGDR +MD++GY  F+GR+DD+IN+S Y
Sbjct: 418 IRIKPVRPVSLFMCYEGDPEKTAKVECGDFYNTGDRGKMDEEGYICFLGRSDDIINASGY 477

Query: 481 RIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHV 540
           RIGP EVESAL EHPAV ESAVV SPDPIRGEVVKAFIVLTP + SHD + LT+ELQ+HV
Sbjct: 478 RIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQHV 537

Query: 541 KRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWGK 579
           K VTAPYKYPRKV FVSELPKT++GKI+R +LR +E G+
Sbjct: 538 KSVTAPYKYPRKVEFVSELPKTITGKIERKELRKKETGQ 576


>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score =  649 bits (1675), Expect = 0.0
 Identities = 306/538 (56%), Positives = 398/538 (73%), Gaps = 2/538 (0%)

Query: 41  AISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSR 100
           ++  G Q VP  FNFA DVLD W+ +E+AG R P+PA WWVNG G E+ W+F EL + S+
Sbjct: 32  SLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQ 91

Query: 101 KAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQA 160
           +AANVL GACGLQ GDR+ +VLPR+PEWWLV + C+R G + +PG  Q+   D+ YRLQ 
Sbjct: 92  QAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQM 151

Query: 161 SRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTK 220
           S+AK+I+  D +   VD +++ECPSL+ KLLVS+ S  GWLNF++LL EAST H+C+ T 
Sbjct: 152 SKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETG 211

Query: 221 SRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWV-KAA 279
           S++  AIYFTSGT+G PKM EHS SS GL        W  L  SDI W  +DTGW+    
Sbjct: 212 SQEASAIYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNIL 270

Query: 280 WTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQS 339
            +L   W  G+C FVH LP+ D  VIL TLS +PI ++   P ++R+L+Q+DL+ Y+F  
Sbjct: 271 CSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPH 330

Query: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399
           L++C+T GE+L P+  E W+ QTG+++ E YGQ+ET + C   K MKIK G MG A+  Y
Sbjct: 331 LQNCVTVGESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCY 390

Query: 400 DVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARM 459
           DVQI+DD+GNVLPPG EG++ +R++P RP   F+ Y+DNP+KTAA+ +GDF++ GDR   
Sbjct: 391 DVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIK 450

Query: 460 DKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIV 519
           D+DGYF FMGR DD+INSS YRIGP EVE+AL EHPAV+E+AV+SSPDP+RGEVVKAF+V
Sbjct: 451 DEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVV 510

Query: 520 LTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEW 577
           L   + SHDPE LT+ELQ+HVK VTAPYKYPRK+ FV  LPKTV+GKIQR+KLR +EW
Sbjct: 511 LASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEW 568


>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score =  646 bits (1667), Expect = 0.0
 Identities = 301/538 (55%), Positives = 399/538 (74%), Gaps = 2/538 (0%)

Query: 41  AISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSR 100
           ++  G Q VP  FNFA DVLD W+ +E+AG R P+PA WWVNG G E+ W+F EL + S+
Sbjct: 32  SLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQ 91

Query: 101 KAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQA 160
           +AAN+L GACGLQ GDR+ ++LPR+PEWWLV + C+R G + +PG  Q+   D+ YRLQ 
Sbjct: 92  QAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQM 151

Query: 161 SRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTK 220
           S+AK+I+  D +   VD +++ECPSL+ KLLVS+ S  GWLNF++LL EAST H+C+ T 
Sbjct: 152 SKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETG 211

Query: 221 SRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWV-KAA 279
           S++  AIYFTSGT+G PKM EHS SS GL        W  L  SDI W  +DTGW+    
Sbjct: 212 SQEASAIYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNIL 270

Query: 280 WTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQS 339
            +L  +W  G+C FVH LP+ D  VIL TLS +PI ++   P ++R+L+Q+DL+ Y+F  
Sbjct: 271 GSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPH 330

Query: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399
           L++CL GGE+L P+  E W+ QTG+++ E YGQ+ET + C   K MKIK G MG A+  Y
Sbjct: 331 LQNCLAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCY 390

Query: 400 DVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARM 459
           DVQ++DD+GNVLPPG EG++ +R++P RP   F+ Y++NP+KTAA+ +GDF++ GDR   
Sbjct: 391 DVQVIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIK 450

Query: 460 DKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIV 519
           D+DGYF FMGR DD+INSS YRIGP EVE+AL +HPAV+E+AV+SSPDP+RGEVVKAF++
Sbjct: 451 DEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510

Query: 520 LTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEW 577
           L   + SHDPE LT+ELQ+HVK VTAPYKYPRK+ FV  LPKTV+GKIQR+KLR +EW
Sbjct: 511 LASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEW 568


>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score =  646 bits (1667), Expect = 0.0
 Identities = 301/538 (55%), Positives = 399/538 (74%), Gaps = 2/538 (0%)

Query: 41  AISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSR 100
           ++  G Q VP  FNFA DVLD W+ +E+AG R P+PA WWVNG G E+ W+F EL + S+
Sbjct: 32  SLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQ 91

Query: 101 KAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQA 160
           +AAN+L GACGLQ GDR+ ++LPR+PEWWLV + C+R G + +PG  Q+   D+ YRLQ 
Sbjct: 92  QAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQM 151

Query: 161 SRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTK 220
           S+AK+I+  D +   VD +++ECPSL+ KLLVS+ S  GWLNF++LL EAST H+C+ T 
Sbjct: 152 SKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETG 211

Query: 221 SRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWV-KAA 279
           S++  AIYFTSGT+G PKM EHS SS GL        W  L  SDI W  +DTGW+    
Sbjct: 212 SQEASAIYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNIL 270

Query: 280 WTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQS 339
            +L  +W  G+C FVH LP+ D  VIL TLS +PI ++   P ++R+L+Q+DL+ Y+F  
Sbjct: 271 GSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPH 330

Query: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399
           L++CL GGE+L P+  E W+ QTG+++ E YGQ+ET + C   K MKIK G MG A+  Y
Sbjct: 331 LQNCLAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCY 390

Query: 400 DVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARM 459
           DVQ++DD+GNVLPPG EG++ +R++P RP   F+ Y++NP+KTAA+ +GDF++ GDR   
Sbjct: 391 DVQVIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIK 450

Query: 460 DKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIV 519
           D+DGYF FMGR DD+INSS YRIGP EVE+AL +HPAV+E+AV+SSPDP+RGEVVKAF++
Sbjct: 451 DEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 510

Query: 520 LTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEW 577
           L   + SHDPE LT+ELQ+HVK VTAPYKYPRK+ FV  LPKTV+GKIQR+KLR +EW
Sbjct: 511 LASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEW 568


>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 2 [Homo sapiens]
          Length = 571

 Score =  597 bits (1538), Expect = e-170
 Identities = 290/538 (53%), Positives = 382/538 (71%), Gaps = 8/538 (1%)

Query: 41  AISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSR 100
           ++  G Q VP  FNFA DVLD W+ +E+AG R P+PA WWVNG G E+ W+F EL + S+
Sbjct: 32  SLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQ 91

Query: 101 KAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQA 160
           +AANVL GACGLQ GDR+ ++LPR+PEWWLV + C+R G + +PG  Q+   D+ YRLQ 
Sbjct: 92  QAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQM 151

Query: 161 SRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTK 220
           S+AK+I+  D +   VD +++ECPSL+ KLLVS+ S  GWLNF++LL EAST H+C+ T 
Sbjct: 152 SKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETG 211

Query: 221 SRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWV-KAA 279
           S++  AIYFTSGT+G PKM EHS SS GL        W  L  SDI W  +DTGW+    
Sbjct: 212 SQEASAIYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNIL 270

Query: 280 WTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQS 339
            +L  +W  G+C FVH LP+ D  VIL TLS +PI ++   P ++R+L+Q+DL+ Y+F  
Sbjct: 271 GSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPH 330

Query: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399
           L++CL GGE+L P+  E W+ QTG+++ E YGQ+ET + C   K MKIK G MG A+  Y
Sbjct: 331 LQNCLAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCY 390

Query: 400 DVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARM 459
           DVQ++     V      G++      T  FC    + +NP+KTAA+ +GDF++ GDR   
Sbjct: 391 DVQVI---AFVHGSPRAGDLGFAGTMTLSFC---GHQENPDKTAANIRGDFWLLGDRGIK 444

Query: 460 DKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIV 519
           D+DGYF FMGR DD+INSS YRIGP EVE+AL +HPAV+E+AV+SSPDP+RGEVVKAF++
Sbjct: 445 DEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504

Query: 520 LTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEW 577
           L   + SHDPE LT+ELQ+HVK VTAPYKYPRK+ FV  LPKTV+GKIQR+KLR +EW
Sbjct: 505 LASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEW 562


>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 1 [Homo sapiens]
          Length = 571

 Score =  597 bits (1538), Expect = e-170
 Identities = 290/538 (53%), Positives = 382/538 (71%), Gaps = 8/538 (1%)

Query: 41  AISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSR 100
           ++  G Q VP  FNFA DVLD W+ +E+AG R P+PA WWVNG G E+ W+F EL + S+
Sbjct: 32  SLQWGHQEVPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQ 91

Query: 101 KAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQA 160
           +AANVL GACGLQ GDR+ ++LPR+PEWWLV + C+R G + +PG  Q+   D+ YRLQ 
Sbjct: 92  QAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQM 151

Query: 161 SRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTK 220
           S+AK+I+  D +   VD +++ECPSL+ KLLVS+ S  GWLNF++LL EAST H+C+ T 
Sbjct: 152 SKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETG 211

Query: 221 SRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWV-KAA 279
           S++  AIYFTSGT+G PKM EHS SS GL        W  L  SDI W  +DTGW+    
Sbjct: 212 SQEASAIYFTSGTSGLPKMAEHSYSSLGLK-AKMDAGWTGLQASDIMWTISDTGWILNIL 270

Query: 280 WTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQS 339
            +L  +W  G+C FVH LP+ D  VIL TLS +PI ++   P ++R+L+Q+DL+ Y+F  
Sbjct: 271 GSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPH 330

Query: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPY 399
           L++CL GGE+L P+  E W+ QTG+++ E YGQ+ET + C   K MKIK G MG A+  Y
Sbjct: 331 LQNCLAGGESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCY 390

Query: 400 DVQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARM 459
           DVQ++     V      G++      T  FC    + +NP+KTAA+ +GDF++ GDR   
Sbjct: 391 DVQVI---AFVHGSPRAGDLGFAGTMTLSFC---GHQENPDKTAANIRGDFWLLGDRGIK 444

Query: 460 DKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIV 519
           D+DGYF FMGR DD+INSS YRIGP EVE+AL +HPAV+E+AV+SSPDP+RGEVVKAF++
Sbjct: 445 DEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVI 504

Query: 520 LTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEW 577
           L   + SHDPE LT+ELQ+HVK VTAPYKYPRK+ FV  LPKTV+GKIQR+KLR +EW
Sbjct: 505 LASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEW 562


>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
           sapiens]
          Length = 438

 Score =  481 bits (1239), Expect = e-136
 Identities = 211/356 (59%), Positives = 283/356 (79%), Gaps = 1/356 (0%)

Query: 49  VPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGG 108
           +PEYFNFA DVLD W+  E+AG +P NPAFWW+N  G E++WSFEELG  SRK AN+L  
Sbjct: 54  IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113

Query: 109 ACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIIT 168
           AC LQ GDR++L+LPR+PEWWL +VAC+RTGTV+IPG TQLT+KD+ YRLQ+S+A  IIT
Sbjct: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173

Query: 169 SDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIY 228
           +D LAP VDA++++C +L +KL+VS++SR GW N +EL++ AS  H C++TK  + +AI+
Sbjct: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233

Query: 229 FTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAW-TLFSAWP 287
           FTSGT+G PKM  H+ SS+GLG   +GR W+ LT SD+ WNT+DTGW K+AW ++FS W 
Sbjct: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293

Query: 288 NGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGG 347
            G+C+F H LPR +   IL TLSK+PIT  C  PT++R+LVQ D+T Y+F+SL+HC++ G
Sbjct: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353

Query: 348 EALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQI 403
           E + PDV EKW+++TG+++YEGYGQ+ETV+IC N KGMKIK GSMGK SP +DV++
Sbjct: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
           sapiens]
          Length = 480

 Score =  420 bits (1079), Expect = e-117
 Identities = 201/438 (45%), Positives = 297/438 (67%), Gaps = 2/438 (0%)

Query: 47  QLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVL 106
           Q V + FNFA DVLD WS+LE+ G R P PA W V+  G E KWSFE + + S+KAA++L
Sbjct: 43  QAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASIL 102

Query: 107 GGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSI 166
              C L  GDR+M++LP  PE + + +AC+R G   +PG  QLT K ++Y+L+ S+A+ I
Sbjct: 103 SDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCI 162

Query: 167 ITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLA 226
           + ++++AP V++  ++CP+L+TKLLVSD S  GWL+F++L++ A  +   MRTKS+DP+A
Sbjct: 163 VANEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMA 222

Query: 227 IYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDT-GWVKAAWTLFSA 285
           I+FT GTTGAPKMVE+SQ   G+GF  + RRW+ L  +D+ W+  D  G   +   +   
Sbjct: 223 IFFTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGT 282

Query: 286 WPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQED-LTRYQFQSLRHCL 344
           W  G+C+F+  +P    + +LN LS+FPITTL   P +++ L+Q    T Y+F+SL+ C+
Sbjct: 283 WFQGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCV 342

Query: 345 TGGEALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIV 404
             G  ++P V E WK  T +++YEGYGQ+ET ++CA  K +K+K  S+GK  PPY VQIV
Sbjct: 343 AAGGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIV 402

Query: 405 DDEGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGY 464
           D+  N+LPPGEEGN+A+RI+  +P   +  ++ + E+ A++     Y+TGDR  MD+DGY
Sbjct: 403 DENSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGY 462

Query: 465 FWFMGRNDDVINSSSYRI 482
           FW+ GR DDV N+   R+
Sbjct: 463 FWWSGRVDDVANALGQRL 480


>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
           1 [Homo sapiens]
          Length = 701

 Score =  179 bits (455), Expect = 5e-45
 Identities = 162/576 (28%), Positives = 264/576 (45%), Gaps = 65/576 (11%)

Query: 54  NFAHDVLDVWSRLEEAGHRPPNPAFWWV-NGTGAEIKWSFEELGKQSRKAANVLGGACGL 112
           N  ++VLD     ++ G +    AF+W  N  G   + ++ +L  Q  + +NVL    G+
Sbjct: 102 NICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GI 157

Query: 113 QPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDS- 171
           Q GDR+ + +P +PE  +  +AC R G +        + + L  R+  S    +IT+D+ 
Sbjct: 158 QKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF 217

Query: 172 --------LAPRVDAISAECPSL--------------QTKLLVSDSSRPG---------- 199
                   L    D    +C                 + +L + DS+             
Sbjct: 218 YRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277

Query: 200 ---W-----LNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGF 251
              W     L + EL++EA  E       + DPL I +TSG+TG PK V H+   Y L +
Sbjct: 278 QISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYML-Y 336

Query: 252 VASGRRWVA-LTESDIFWNTTDTGWVKA-AWTLFSAWPNGSCIFVHE-LPRV-DAKVILN 307
           VA+  ++V      D+FW T D GW+   ++  +    NG+   + E +P   D   + +
Sbjct: 337 VATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWS 396

Query: 308 TLSKFPITTLCCVPTIFRLLVQ---EDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGV 364
            + K+ +T     PT  RLL++   E +T++   SL+   T GE +NP+    +    G 
Sbjct: 397 IVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGA 456

Query: 365 E---LYEGYGQSETV--VICANPKGMKIKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNV 419
           +   + + + Q+ET   ++   P    +K GS           I+++ G  L    EG +
Sbjct: 457 QRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYL 516

Query: 420 AVRIRPTRPFCFFNCYLDNP--EKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINS 477
               +   P      Y ++   E T   +   +Y+TGD  + D+DGY+W  GR DD++N 
Sbjct: 517 V--FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNV 574

Query: 478 SSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQ 537
           S + +   EVESAL EH AV E+AVV  P P++GE +  F+ L   + +  P+ LT EL+
Sbjct: 575 SGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGH-TFSPK-LTEELK 632

Query: 538 EHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLR 573
           + ++    P   P  +     LPKT SGKI R  LR
Sbjct: 633 KQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 668


>gi|253970489 acyl-CoA synthetase short-chain family member 2
           isoform 2 [Homo sapiens]
          Length = 714

 Score =  179 bits (454), Expect = 6e-45
 Identities = 162/589 (27%), Positives = 262/589 (44%), Gaps = 78/589 (13%)

Query: 54  NFAHDVLDVWSRLEEAGHRPPNPAFWWV-NGTGAEIKWSFEELGKQSRKAANVLGGACGL 112
           N  ++VLD     ++ G +    AF+W  N  G   + ++ +L  Q  + +NVL    G+
Sbjct: 102 NICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GI 157

Query: 113 QPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSL 172
           Q GDR+ + +P +PE  +  +AC R G +        + + L  R+  S    +IT+D+ 
Sbjct: 158 QKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF 217

Query: 173 ----------------------------------------------APRVDAISAECPSL 186
                                                           +   I   CP +
Sbjct: 218 YRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277

Query: 187 QTKLLVSDSS---RPGW-----LNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPK 238
           Q KL         +  W     L + EL++EA  E       + DPL I +TSG+TG PK
Sbjct: 278 QGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPK 337

Query: 239 MVEHSQSSYGLGFVASGRRWVA-LTESDIFWNTTDTGWVKA-AWTLFSAWPNGSCIFVHE 296
            V H+   Y L +VA+  ++V      D+FW T D GW+   ++  +    NG+   + E
Sbjct: 338 GVVHTVGGYML-YVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFE 396

Query: 297 -LPRV-DAKVILNTLSKFPITTLCCVPTIFRLLVQ---EDLTRYQFQSLRHCLTGGEALN 351
            +P   D   + + + K+ +T     PT  RLL++   E +T++   SL+   T GE +N
Sbjct: 397 GIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPIN 456

Query: 352 PDVREKWKHQTGVE---LYEGYGQSETV--VICANPKGMKIKSGSMGKASPPYDVQIVDD 406
           P+    +    G +   + + + Q+ET   ++   P    +K GS           I+++
Sbjct: 457 PEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNE 516

Query: 407 EGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNP--EKTAASEQGDFYITGDRARMDKDGY 464
            G  L    EG +    +   P      Y ++   E T   +   +Y+TGD  + D+DGY
Sbjct: 517 SGEELEGEAEGYLV--FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGY 574

Query: 465 FWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAY 524
           +W  GR DD++N S + +   EVESAL EH AV E+AVV  P P++GE +  F+ L   +
Sbjct: 575 YWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGH 634

Query: 525 SSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLR 573
            +  P+ LT EL++ ++    P   P  +     LPKT SGKI R  LR
Sbjct: 635 -TFSPK-LTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681


>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
           sapiens]
          Length = 689

 Score =  169 bits (427), Expect = 8e-42
 Identities = 151/524 (28%), Positives = 240/524 (45%), Gaps = 33/524 (6%)

Query: 79  WWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRT 138
           W  +  G E++ ++ EL + + + AN L    G+  GDR+ + +P  P      +AC R 
Sbjct: 130 WERDEPGTEVRITYRELLETTCRLANTLKRH-GVHRGDRVAIYMPVSPLAVAAMLACARI 188

Query: 139 GTVMIPGVTQLTEKDLKYRLQASRAKSIITSDS---------LAPRVDAISAECPSLQTK 189
           G V        + + L  R+  ++ K +IT +          L   VD     CP++Q  
Sbjct: 189 GAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHV 248

Query: 190 LLVSDSSRPGWLNFRELLRE---ASTEHNCMRTK--SRDPLAIYFTSGTTGAPKMVEHSQ 244
           L+   +     +   ++  E   A  +  C      S D L + +TSG+TG PK + H+Q
Sbjct: 249 LVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQ 308

Query: 245 SSYGLGFVASGRRWVALTESDIFWNTTDTGWVKA-AWTLFSAWPNGSCIFVHELPRV--D 301
           + Y L    + +        DIF    D GW+   ++ ++    NG+   + E   V  +
Sbjct: 309 AGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPN 368

Query: 302 AKVILNTLSKFPITTLCCVPTIFRLLVQED---LTRYQFQSLRHCLTGGEALNPDVREKW 358
           A     T+ +  I      PT  RLL++     + +Y   SLR   + GE +N +  E W
Sbjct: 369 AGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWE-W 427

Query: 359 KHQ----TGVELYEGYGQSETVVICANPKGMKIKSGSM-GKASPPYD--VQIVDDEGNVL 411
            H+    +   L + + Q+ET  IC  P+  +  +  +   A  P+   V ++ DE   +
Sbjct: 428 LHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSV 487

Query: 412 PPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQG--DFYITGDRARMDKDGYFWFMG 469
             G   + A+ I    P      Y D+     A  +    +Y TGD A   + GY+   G
Sbjct: 488 VEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITG 547

Query: 470 RNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDP 529
           R DDVIN S +R+G  E+E A+A+HPAV ESAV+  P  I+GE   AFIV+    S+ D 
Sbjct: 548 RMDDVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIVVKD--SAGDS 605

Query: 530 EALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLR 573
           + + +EL+  V    A Y  P ++  V  LPKT SGK+ R  LR
Sbjct: 606 DVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKVMRRLLR 649


>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
           sapiens]
          Length = 686

 Score =  166 bits (420), Expect = 5e-41
 Identities = 144/529 (27%), Positives = 241/529 (45%), Gaps = 37/529 (6%)

Query: 84  TGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMI 143
           T  +  ++++E+ +Q  K A VL    G++ GD +++ +P +P+     +AC R G +  
Sbjct: 138 TNTKATFTYKEVLEQVSKLAGVLVKH-GIKKGDTVVIYMPMIPQAMYTMLACARIGAIHS 196

Query: 144 PGVTQLTEKDLKYRLQASRAKSIITSD-SLAP--RVDAISAECPSLQT------KLLVSD 194
                   K+L  R+   + K ++T+   + P  RV+ +     +L+       K+L+ +
Sbjct: 197 LIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYN 256

Query: 195 SSR-------PGW-LNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSS 246
                     PG  L++ E + +A + H+C+   S  PL I +TSGTTG PK V      
Sbjct: 257 RPNMEAVPLAPGRDLDWDEEMAKAQS-HDCVPVLSEHPLYILYTSGTTGLPKGVIRPTGG 315

Query: 247 YGLGFVASGRRWVALTESDIFWNTTDTGWVKA-AWTLFSAWPNGSCIFVHELPRV---DA 302
           Y +    S      L   +++W  +D GWV   ++  +    +G+   ++E   V   DA
Sbjct: 316 YAVMLHWSMSSIYGLQPGEVWWAASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDA 375

Query: 303 KVILNTLSKFPITTLCCVPTIFRLLVQEDL-----TRYQFQSLRHCLTGGEALNPDVREK 357
                 L++  +  L   PT  R + Q+D       +Y     +     GE  + +  E 
Sbjct: 376 GAYFRVLAEHGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEW 435

Query: 358 WKHQTGVELYEGYGQSET----VVICANPKGMKIKS-GSMGKASPPYDVQIVDDEGNVLP 412
            K+   V + + + Q+ET       C      K    G  GK+ P Y+V I+DD    L 
Sbjct: 436 SKNVFRVPVLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLK 495

Query: 413 PGEEGNVAVRIRPTRPFCFFNCYLDNP--EKTAASEQGDFYITGDRARMDKDGYFWFMGR 470
               GN+ V++ P  P  F   + +    +     +   +Y T D   MD++GY + M R
Sbjct: 496 ARCLGNIVVKL-PLPPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSR 554

Query: 471 NDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPE 530
            DDVIN + +RI    +E ++  H  V + AVV   DP++G V  A  VL    ++ + +
Sbjct: 555 VDDVINVAGHRISAGAIEESILSHGTVADCAVVGKEDPLKGHVPLALCVLRKDINATEEQ 614

Query: 531 ALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWGK 579
            L  E+ +HV++   P    R   FV +LPKT SGKI RS L +   GK
Sbjct: 615 VL-EEIVKHVRQNIGPVAAFRNAVFVKQLPKTRSGKIPRSALSAIVNGK 662


>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score =  129 bits (323), Expect = 1e-29
 Identities = 137/530 (25%), Positives = 220/530 (41%), Gaps = 75/530 (14%)

Query: 91  SFEELGKQSRKAANVLGGACGLQPGD----RMMLVLPRLPEWWLVSVACMRTGTVMIPGV 146
           ++ EL  +S + +  +   CG   GD    R+  +      + +   A   +G V +P  
Sbjct: 67  TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126

Query: 147 TQLTEKDLKYRLQASRAKSIITSDS----LAPRVDAISAECPSLQTKLLVSDSSRPGWLN 202
            +     L+Y +  S++  ++ S      L+P V  +      L   +       P    
Sbjct: 127 RKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVEEPA--- 183

Query: 203 FRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALT 262
                 E        R K      I +TSGTTG PK V  +  +          +W A T
Sbjct: 184 ------EVPVPEQGWRNKGA---MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW-AWT 233

Query: 263 ESDIFWNTTDTGWVKAAWT--LFSAWPNGSCIFVHELP--RVDAKVILNTLSKFPITTLC 318
           + D+  +      V       L   W   +C+ + E    +V  K + +   +  I    
Sbjct: 234 KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPR--INVFM 291

Query: 319 CVPTIFRLLV------------QEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGVEL 366
            VPTI+  L+            Q+ L     + +R  ++G  AL   V EKWK+ TG  L
Sbjct: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351

Query: 367 YEGYGQSETVVICANPKGMKIK-SGSMGKASPPYDVQIV-----------------DDEG 408
            E YG +E  +  + P    ++  GS+G   P   V+IV                 D+ G
Sbjct: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411

Query: 409 NVLPPG---EEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGD-FYITGDRARMDKDGY 464
             + PG   +EG + VR  P+     F  Y + PE+T ++   D ++ TGD   + KDG 
Sbjct: 412 TKVTPGFEEKEGELLVR-GPS----VFREYWNKPEETKSAFTLDGWFKTGDTV-VFKDGQ 465

Query: 465 FWFMGRND-DVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPA 523
           +W  GR   D+I +  Y++  +EVE  L  HP++ + AV+  PD   G+ V A + L   
Sbjct: 466 YWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREG 525

Query: 524 YS-SHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKL 572
           +S SH      REL+E  + V APY  P ++  V E+P+   GKI +  L
Sbjct: 526 HSLSH------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score =  129 bits (323), Expect = 1e-29
 Identities = 137/530 (25%), Positives = 220/530 (41%), Gaps = 75/530 (14%)

Query: 91  SFEELGKQSRKAANVLGGACGLQPGD----RMMLVLPRLPEWWLVSVACMRTGTVMIPGV 146
           ++ EL  +S + +  +   CG   GD    R+  +      + +   A   +G V +P  
Sbjct: 67  TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126

Query: 147 TQLTEKDLKYRLQASRAKSIITSDS----LAPRVDAISAECPSLQTKLLVSDSSRPGWLN 202
            +     L+Y +  S++  ++ S      L+P V  +      L   +       P    
Sbjct: 127 RKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVEEPA--- 183

Query: 203 FRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALT 262
                 E        R K      I +TSGTTG PK V  +  +          +W A T
Sbjct: 184 ------EVPVPEQGWRNKGA---MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW-AWT 233

Query: 263 ESDIFWNTTDTGWVKAAWT--LFSAWPNGSCIFVHELP--RVDAKVILNTLSKFPITTLC 318
           + D+  +      V       L   W   +C+ + E    +V  K + +   +  I    
Sbjct: 234 KDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPR--INVFM 291

Query: 319 CVPTIFRLLV------------QEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGVEL 366
            VPTI+  L+            Q+ L     + +R  ++G  AL   V EKWK+ TG  L
Sbjct: 292 AVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTL 351

Query: 367 YEGYGQSETVVICANPKGMKIK-SGSMGKASPPYDVQIV-----------------DDEG 408
            E YG +E  +  + P    ++  GS+G   P   V+IV                 D+ G
Sbjct: 352 LERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERG 411

Query: 409 NVLPPG---EEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGD-FYITGDRARMDKDGY 464
             + PG   +EG + VR  P+     F  Y + PE+T ++   D ++ TGD   + KDG 
Sbjct: 412 TKVTPGFEEKEGELLVR-GPS----VFREYWNKPEETKSAFTLDGWFKTGDTV-VFKDGQ 465

Query: 465 FWFMGRND-DVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPA 523
           +W  GR   D+I +  Y++  +EVE  L  HP++ + AV+  PD   G+ V A + L   
Sbjct: 466 YWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREG 525

Query: 524 YS-SHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKL 572
           +S SH      REL+E  + V APY  P ++  V E+P+   GKI +  L
Sbjct: 526 HSLSH------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569


>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
          Length = 615

 Score =  125 bits (313), Expect = 1e-28
 Identities = 135/526 (25%), Positives = 225/526 (42%), Gaps = 51/526 (9%)

Query: 87  EIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGV 146
           +++ +F +L ++  KAA+ L  + GL  GDR+ +  P    W L+ +A  + G +++   
Sbjct: 97  DVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVN 155

Query: 147 TQLTEKDLKYRLQASRAKSIITSDSLAPR--VDAISAECPSLQ---------------TK 189
                 +L+Y L+    K+++       +   + +   CP ++               T 
Sbjct: 156 PAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTT 215

Query: 190 LLVSDSSRPGWLNFRELLREAST-------EHNCMRTKSRDPLAIYFTSGTTGAPKMVEH 242
           ++  D+  PG L   E++   ST       ++N       DP+ I FTSGTTG+PK    
Sbjct: 216 VISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATL 275

Query: 243 SQSSYGLGFVASGRRWVALTESD------IFWNTTDTGWVKAAWTLFSAWPNGSCIFVHE 296
           S  +        G R + L E        I  N         A T+       + I    
Sbjct: 276 SHYNIVNNSNILGER-LKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILAS- 333

Query: 297 LPRVDAKVILNTLSKFPITTLCCVPTIF-RLLVQEDLTRYQFQSLRHCLTGGEALNPDVR 355
            P  + K  L  +S+   T L   PT+F  +L Q D + Y   ++   +  G    P++ 
Sbjct: 334 -PIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELI 392

Query: 356 EKWKHQTGV-ELYEGYGQSET--VVICANPKG-MKIKSGSMGKASPPYDVQIVDDEGNVL 411
               ++  + +L   YG +E   V     P+  ++ K+ S+G+  P  + +I++ E   L
Sbjct: 393 RAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTL 452

Query: 412 PP-GEEGNVAVRIRPTRPFCFFNCYLDNPEKTA-ASEQGDFYITGDRARMDKDGYFWFMG 469
                 G + +R      +C    Y   P+KT  A +Q  +Y TGD A M++ G+   +G
Sbjct: 453 AKLNTPGELCIR-----GYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVG 507

Query: 470 RNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDP 529
           R+ D+I      I P E+E     HP V E  VV   D   GE + A I L         
Sbjct: 508 RSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL-----KDGE 562

Query: 530 EALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQ 575
           E    E++   K   + +K P+ + FV+  P T+SGKIQ+ KLR Q
Sbjct: 563 ETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608


>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
          Length = 646

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 129/518 (24%), Positives = 211/518 (40%), Gaps = 46/518 (8%)

Query: 90  WSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQL 149
           W+F +L   S   AN+     G  PGD + + L   PE+  + +   + G         L
Sbjct: 104 WTFAQLDAYSNAVANLFR-QLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162

Query: 150 TEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLN----FRE 205
             + L + L  S AK++I    +   V  +S        K    D    G L        
Sbjct: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222

Query: 206 LLREASTEHNC-MRTKSRDPLAIY-FTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTE 263
           LL+EAST     + +K  D    Y +TSGTTG PK      S Y     A G     +  
Sbjct: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRY-YRMAAFGHHAYRMQA 281

Query: 264 SDIFWNTTDTGWVKAAWTLFSAWPNGSCIF----VHELPRVDAKVILNTLSKFPITTLCC 319
           +D+ ++        +A  +      G C+     V    +  A    +   K+  T +  
Sbjct: 282 ADVLYDCLPL--YHSAGNIIGV---GQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQY 336

Query: 320 VPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTGV-ELYEGYGQSETVVI 378
           +  I R L+++ +   + +  R  L  G  L P + E++  + GV ++ E YG +E    
Sbjct: 337 IGEICRYLLKQPVREAERRH-RVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCS 395

Query: 379 CANPKGMKIKSGSMGKASPP-YDVQIV-----------DDEGNVLP--PGEEGNVAVRIR 424
            AN  G     G   +  P  Y +++V           D +G  +P   GE G +  +I 
Sbjct: 396 IANMDGKVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQIN 455

Query: 425 PTRPFCFFNCYLDNP---EKTAAS--EQGDF-YITGDRARMDKDGYFWFMGRNDDVINSS 478
              P   F+ Y+      +K A S   +GD  Y++GD   MD+ GY +F  R+ D     
Sbjct: 456 QQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWR 515

Query: 479 SYRIGPVEVESALAEHPAVLESAVVSSPDP-IRGEVVKAFIVLTPAYSSHDPEALTRELQ 537
              +   EVE  L+      + AV     P + G+   A   +   +S  DP A+ +ELQ
Sbjct: 516 GENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMA--AVADPHSLLDPNAIYQELQ 573

Query: 538 EHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQ 575
               +V APY  P  +  + ++  T + KIQ+++L+ +
Sbjct: 574 ----KVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQRE 607


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 131/529 (24%), Positives = 206/529 (38%), Gaps = 93/529 (17%)

Query: 102 AANVLGGACGLQPGDRMMLVLPRLPE----WWLVSVACMRTGTVMIPGVTQLTEKDLKYR 157
           AA   G A  L PG  + L+LP  PE    W+ ++ A +RT  V     T L    L + 
Sbjct: 201 AARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVP----TALRRGPLLHC 256

Query: 158 LQASRAKSIITSDSLAPR-VDAISAECPSLQTKLLVSDSSRPGW--LNFRELLREASTE- 213
           L++  A++++    LAP  ++++  + P+L+   L   ++ PG       +LL E S E 
Sbjct: 257 LRSCGARALV----LAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEV 312

Query: 214 ------HNCMRTKSRDPLAIYFTSGTTGAPKM--VEHSQSSYGLGFVASGRRWVALTESD 265
                 +        D     FTSGTTG PK   + H +     GF     +   + + D
Sbjct: 313 DGPVPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKILQCQGFY----QLCGVHQED 368

Query: 266 IFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFP------------ 313
           + +          A  L+    +GS + +     + A V+L   SKF             
Sbjct: 369 VIY---------LALPLYHM--SGSLLGIVGCMGIGATVVLK--SKFSAGQFWEDCQQHR 415

Query: 314 ITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTG-VELYEGYGQ 372
           +T    +  + R LV +  ++ + +  +  L  G  L PD  E++  + G +++ E YG 
Sbjct: 416 VTVFQYIGELCRYLVNQPPSKAE-RGHKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGL 474

Query: 373 SETVVICANPKGMKIKSGSMGKAS-----------PPYDVQ----IVDDEGNVLP--PGE 415
           +E  V   N  G +   G++G+AS             YDV     I D +G+ +   PGE
Sbjct: 475 TEGNVATINYTGQR---GAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGE 531

Query: 416 EGNVAVRIRPTRPFCFFNCYLDNPEKTAAS------EQGD-FYITGDRARMDKDGYFWFM 468
            G +   +    PF     Y   PE             GD F+ TGD    D  G+  F 
Sbjct: 532 PGLLVAPVSQQSPFLG---YAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFH 588

Query: 469 GRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDP-IRGEVVKAFIVLTPAYSSH 527
            R  D        +   EV         + E  V     P   G    A +VL P     
Sbjct: 589 DRTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRP----- 643

Query: 528 DPEALT-RELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQ 575
            P AL   +L  HV     PY  PR +     L  T + K Q+ ++ ++
Sbjct: 644 -PHALDLMQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANE 691


>gi|40807357 solute carrier family 27 (fatty acid transporter),
           member 4 [Homo sapiens]
          Length = 643

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 127/526 (24%), Positives = 209/526 (39%), Gaps = 53/526 (10%)

Query: 85  GAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIP 144
           G +  W+F +L + S   AN L  A GL  GD   + +    E+  + +   + G     
Sbjct: 97  GTDTHWTFRQLDEYSSSVANFLQ-ARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAAL 155

Query: 145 GVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAISAEC-PSLQTKLLVSDSSRPGWL-- 201
             T L    L + L  SRA++++    +A  +  + A   PSL   L  S S  PG +  
Sbjct: 156 INTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLS--LFCSGSWEPGAVPP 213

Query: 202 ---NFRELLREASTE-HNCMRTKSRDPLAIYFTSGTTGAPK--MVEHSQSSYGLGFVASG 255
              +   LL++A     +C      D L   +TSGTTG PK  +V HS+       V  G
Sbjct: 214 STEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYG 273

Query: 256 RRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIF----VHELPRVDAKVILNTLSK 311
            R   +  +DI ++        +A  +      G C+     V    +  A    +   K
Sbjct: 274 FR---MRPNDIVYDCLPL--YHSAGNIVGI---GQCLLHGMTVVIRKKFSASRFWDDCIK 325

Query: 312 FPITTLCCVPTIFRLLVQEDLTRYQFQ-SLRHCLTGGEALNPDVREKWKHQTGV-ELYEG 369
           +  T +  +  + R L+ +     + Q  +R  L  G  L   +   +  +  + ++ E 
Sbjct: 326 YNCTIVQYIGELCRYLLNQPPREAENQHQVRMAL--GNGLRQSIWTNFSSRFHIPQVAEF 383

Query: 370 YGQSETVVICANPKGMKIKSGSMGKA-SPPYDVQIV-----------DDEGNVLP--PGE 415
           YG +E      N        G   +  S  Y +++V             +G  +P  PGE
Sbjct: 384 YGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGE 443

Query: 416 EGNVAVRIRPTRPFCFFNCYLD---NPEKTAAS--EQGD-FYITGDRARMDKDGYFWFMG 469
            G +  RI    P   F+ YL+   N +K A    ++GD  Y+TGD   MD+ GY +F  
Sbjct: 444 PGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRD 503

Query: 470 RNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDP 529
           R  D        +   EVE  L+    + + AV     P          V +P   + D 
Sbjct: 504 RTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPT-GNCDL 562

Query: 530 EALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQ 575
           E   + L++ +      Y  P  +  + EL KT + K Q+++LR +
Sbjct: 563 ERFAQVLEKELPL----YARPIFLRLLPELHKTGTYKFQKTELRKE 604


>gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens]
          Length = 672

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 79/353 (22%), Positives = 140/353 (39%), Gaps = 13/353 (3%)

Query: 224 PLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLF 283
           PL I F+SGTTGAPK + HS     +  +        +T SDI    T  GW+   W + 
Sbjct: 284 PLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVS 343

Query: 284 SAWPNGSCIFVHELPRVDA-KVILNTLSKFPITTLCCVPTIFRLL---VQEDLTRYQFQS 339
                 + +     P V    V+ + + +  IT L        +L     + +  +  Q 
Sbjct: 344 LLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQM 403

Query: 340 LRHCLTGGEALNPDVREKWKHQTGVELYEGYGQSETVVI---CANPKGMKIKSGSMGKAS 396
           L   L+ G  L     E         +  G     T +I     +   + +  G +   +
Sbjct: 404 LHTILSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARN 463

Query: 397 PPYDVQIVDDEGNVLPPGEEGN-VAVRIRPTRPFCFFNCYLDNP-EKTAASEQGDFYITG 454
               V+  ++EG  +  GE G  V  +  P +P  F+N    N   K   S+    +  G
Sbjct: 464 LGMAVEAWNEEGKAV-WGESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHG 522

Query: 455 DRARMD-KDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEV 513
           D  R++ K G    +GR+D  +N +  R G  E+ + +     V +S  V   +  R E 
Sbjct: 523 DYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREER 582

Query: 514 VKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGK 566
           V  F+ +   + +  P+ L + +++ ++   +    P  +     +P T++GK
Sbjct: 583 VILFLKMASGH-AFQPD-LVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGK 633


>gi|62865631 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 114/517 (22%), Positives = 202/517 (39%), Gaps = 53/517 (10%)

Query: 90  WSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQL 149
           ++++++ K+S + A+V      L+ GD + L++   P++  V     + G V+    T +
Sbjct: 80  YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139

Query: 150 TEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLV---SDSSRPGWLNFREL 206
               L   ++A   ++++    L   V+ I    PSL   + V    DS   G ++ +E 
Sbjct: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEI---LPSLSENISVWGMKDSVPQGVISLKEK 196

Query: 207 LREASTE-----HNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWV-A 260
           L  +  E     H+ +       L I FTSGTTG PK    SQ     G   S   W   
Sbjct: 197 LSTSPDEPVPRSHHVVSLLKSTCLYI-FTSGTTGLPKAAVISQLQVLRG---SAVLWAFG 252

Query: 261 LTESDIFWNTTDTGWVKAAWTLFSAWP--NGSCIFVHELPRVDAKVILNTLSKFPITTLC 318
            T  DI + T       AA    S       +C+      +  A    +   K+ +T   
Sbjct: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCVL---KKKFSASQFWSDCKKYDVTVFQ 309

Query: 319 CVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTG-VELYEGYGQSETVV 377
            +  + R L ++   R   +  +  L  G  +  DV  ++  + G +++ E Y  +E+ +
Sbjct: 310 YIGELCRYLCKQS-KREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSI 368

Query: 378 ICANPKGMKIKSGSMGKAS-----------PPYDVQIVDDEGNV------LPPGEEGNVA 420
              N  G   + G++G+ +             YD Q  +   N       +  GE G + 
Sbjct: 369 SFMNYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425

Query: 421 VRIRPTRPFC-FFNCYLDNPEKTAAS--EQGDFYI-TGDRARMDKDGYFWFMGRNDDVIN 476
            R+    PF  +   Y    +K      ++GD Y+ TGD    D+D + +F  R  D   
Sbjct: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485

Query: 477 SSSYRIGPVEVESALAEHPAVLESAVVS-SPDPIRGEVVKAFIVLTPAYSSHDPEALTRE 535
                +   EV   +     + E+ V   +     G    A I+L P  +S D E    +
Sbjct: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKP-NTSLDLE----K 540

Query: 536 LQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKL 572
           + E V      Y  PR +    ++  T + K+ + +L
Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577


>gi|13325055 solute carrier family 27 (fatty acid transporter),
           member 6 [Homo sapiens]
          Length = 619

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 114/517 (22%), Positives = 202/517 (39%), Gaps = 53/517 (10%)

Query: 90  WSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQL 149
           ++++++ K+S + A+V      L+ GD + L++   P++  V     + G V+    T +
Sbjct: 80  YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139

Query: 150 TEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLV---SDSSRPGWLNFREL 206
               L   ++A   ++++    L   V+ I    PSL   + V    DS   G ++ +E 
Sbjct: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEI---LPSLSENISVWGMKDSVPQGVISLKEK 196

Query: 207 LREASTE-----HNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWV-A 260
           L  +  E     H+ +       L I FTSGTTG PK    SQ     G   S   W   
Sbjct: 197 LSTSPDEPVPRSHHVVSLLKSTCLYI-FTSGTTGLPKAAVISQLQVLRG---SAVLWAFG 252

Query: 261 LTESDIFWNTTDTGWVKAAWTLFSAWP--NGSCIFVHELPRVDAKVILNTLSKFPITTLC 318
            T  DI + T       AA    S       +C+      +  A    +   K+ +T   
Sbjct: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCVL---KKKFSASQFWSDCKKYDVTVFQ 309

Query: 319 CVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTG-VELYEGYGQSETVV 377
            +  + R L ++   R   +  +  L  G  +  DV  ++  + G +++ E Y  +E+ +
Sbjct: 310 YIGELCRYLCKQS-KREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSI 368

Query: 378 ICANPKGMKIKSGSMGKAS-----------PPYDVQIVDDEGNV------LPPGEEGNVA 420
              N  G   + G++G+ +             YD Q  +   N       +  GE G + 
Sbjct: 369 SFMNYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425

Query: 421 VRIRPTRPFC-FFNCYLDNPEKTAAS--EQGDFYI-TGDRARMDKDGYFWFMGRNDDVIN 476
            R+    PF  +   Y    +K      ++GD Y+ TGD    D+D + +F  R  D   
Sbjct: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485

Query: 477 SSSYRIGPVEVESALAEHPAVLESAVVS-SPDPIRGEVVKAFIVLTPAYSSHDPEALTRE 535
                +   EV   +     + E+ V   +     G    A I+L P  +S D E    +
Sbjct: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKP-NTSLDLE----K 540

Query: 536 LQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKL 572
           + E V      Y  PR +    ++  T + K+ + +L
Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577


>gi|227499619 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 1 [Homo sapiens]
          Length = 620

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 121/550 (22%), Positives = 212/550 (38%), Gaps = 64/550 (11%)

Query: 66  LEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRL 125
           LE+A   P  P   + + T      ++ ++ ++S + A  L    GL+ GD + L++   
Sbjct: 60  LEKARQTPHKPFLLFRDET-----LTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNE 114

Query: 126 PEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAI--SAEC 183
           P +  + +  ++ G  M      +  K L +  Q   AK ++ S  L   V+ I  S + 
Sbjct: 115 PAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKK 174

Query: 184 PSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSR----DPLAIYFTSGTTGAPK- 238
             +    +   S+  G  +F + + E STE      +S      P    +TSGTTG PK 
Sbjct: 175 DDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKA 234

Query: 239 -MVEHSQSSYGLGFV-ASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHE 296
            M+ H +  YG G    SG     L   D+ + T    +  +A  L        CI    
Sbjct: 235 AMITHQRIWYGTGLTFVSG-----LKADDVIYITLP--FYHSAALLIGI---HGCIVAGA 284

Query: 297 L----PRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNP 352
                 +  A    +   K+ +T +  +  + R L      +   +  +  L  G  L  
Sbjct: 285 TLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSP-QKPNDRDHKVRLALGNGLRG 343

Query: 353 DVREKWKHQTG-VELYEGYGQSETVVICANPKGMKIKSGSMGKAS-----------PPYD 400
           DV  ++  + G + +YE Y  +E  +   N      K G++G+ +             YD
Sbjct: 344 DVWRQFVKRFGDICIYEFYAATEGNIGFMN---YARKVGAVGRVNYLQKKIITYDLIKYD 400

Query: 401 VQ----IVDDEGNV--LPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASE---QGDFY 451
           V+    + D+ G    +P GE G +  +I    PF  +       EK    +   +GD Y
Sbjct: 401 VEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLY 460

Query: 452 I-TGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAV--VSSPDP 508
             +GD   +D + + +F  R  D        +   EV   +     V E  V  V  PD 
Sbjct: 461 FNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDH 520

Query: 509 IRGEVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQ 568
             G +  A I +     +H+ +   ++L +H+      Y  PR +     +   ++G  +
Sbjct: 521 -EGRIGMASIKMK---ENHEFDG--KKLFQHIADYLPSYARPRFLRIQDTI--EITGTFK 572

Query: 569 RSKLRSQEWG 578
             K+   E G
Sbjct: 573 HRKMTLVEEG 582


>gi|13325057 solute carrier family 27 (fatty acid transporter),
           member 5 [Homo sapiens]
          Length = 690

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 87/386 (22%), Positives = 155/386 (40%), Gaps = 59/386 (15%)

Query: 222 RDPLAIYFTSGTTGAPK--MVEHSQSSYGLGFVASGRRWVAL---TESDIFWNTTDTGWV 276
           R P    +TSGTTG PK  ++ H +       V    + ++L   T  D+ +       V
Sbjct: 287 RSPALFIYTSGTTGLPKPAILTHER-------VLQMSKMLSLSGATADDVVYTVLPLYHV 339

Query: 277 KA--AWTLFSAWPNGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQ----- 329
                  L       +C+     P+       +   +  +T +  V  + R L       
Sbjct: 340 MGLVVGILGCLDLGATCVLA---PKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQP 396

Query: 330 EDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTG-VELYEGYGQSETVVICANPKGMKIK 388
           ED T     ++R  L  G  L  DV E ++ + G + ++E YG +E  +   N  G   +
Sbjct: 397 EDRTH----TVR--LAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVG---R 447

Query: 389 SGSMGKAS------PPYDV---------QIVDDEGNVLPPG--EEGNVAVRIRPTRPFCF 431
            G++GK S       P+++          + D++G  +P G  E G +  ++   +PF  
Sbjct: 448 CGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVG 507

Query: 432 FNCYLDNPEKTAAS---EQGD-FYITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEV 487
           +    +  E+       + GD +Y TGD   MD++G+ +F  R  D        +   EV
Sbjct: 508 YRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEV 567

Query: 488 ESALAEHPAVLESAVVSSPDP-IRGEVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAP 546
           E  L++   + +  V     P   G+V  A + L P   + D E    +L +HV+     
Sbjct: 568 EGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPG-QTFDGE----KLYQHVRAWLPA 622

Query: 547 YKYPRKVAFVSELPKTVSGKIQRSKL 572
           Y  P  +     +  T + K+ +++L
Sbjct: 623 YATPHFIRIQDAMEVTSTFKLMKTRL 648


>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
          Length = 1098

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 84/380 (22%), Positives = 152/380 (40%), Gaps = 40/380 (10%)

Query: 209 EASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFW 268
           E + EH  +R K      ++ TSGTTG PK+V        +  +   R    +T+ D+ +
Sbjct: 178 EKAEEHMDLRLKHCLAYVLH-TSGTTGIPKIVRVPHKCI-VPNIQHFRVLFDITQEDVLF 235

Query: 269 NTTDTGWVKAAWTLFSAWPNGSCIFV--HELPRVDAKVILNTLSKFPITTLCCVPTIFRL 326
             +   +  +   +F A  +G+ + +    +  + +K+     S   +T L   PT+ R 
Sbjct: 236 LASPLTFDPSVVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRR 295

Query: 327 LVQEDLTRYQFQ---SLRHCLTGGEAL-NPDVREKWKHQTG-VELYEGYGQSETVVICAN 381
              + +         SLR    GGEA  +  V   W+ +    +++  YG +E       
Sbjct: 296 FGSQLIKSTVLSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATI 355

Query: 382 PKGMKIKSGSMGKASPPYD---------VQIVDDEGNVLPPGEEGNVAVRIRPTRPFCFF 432
            +  +    S  K   P           V++ D  G  +   +EG+  V +      CF 
Sbjct: 356 YRIPEKTLNSTLKCELPVQLGFPLLGTVVEVRDTNGFTI---QEGSGQVFLGGRNRVCFL 412

Query: 433 NCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALA 492
           +  +  P  T  +  GDF          KDG  +F+GR D  I     R+  +E+   +A
Sbjct: 413 DDEVTVPLGTMRAT-GDFVTV-------KDGEIFFLGRKDSQIKRHGKRLN-IELVQQVA 463

Query: 493 EHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRK 552
           E    +ES  V+  +       +  I+   +  +   E + +ELQ+++      +  P +
Sbjct: 464 EELQQVESCAVTWYNQ------EKLILFMVSKDASVKEYIFKELQKYL----PSHAVPDE 513

Query: 553 VAFVSELPKTVSGKIQRSKL 572
           +  +  LP T  GKI  S+L
Sbjct: 514 LVLIDSLPFTSHGKIDVSEL 533


>gi|209529739 hypothetical protein LOC100132247 [Homo sapiens]
          Length = 1133

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 25/41 (60%), Positives = 30/41 (73%)

Query: 513 VVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKV 553
           +VK  IVLTP + SHD   LT+ELQ+HVK VT P +Y RKV
Sbjct: 1   MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41


>gi|239745501 PREDICTED: similar to acyl-CoA synthetase medium-chain
           family member 2 [Homo sapiens]
          Length = 1122

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 25/41 (60%), Positives = 30/41 (73%)

Query: 513 VVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKV 553
           +VK  IVLTP + SHD   LT+ELQ+HVK VT P +Y RKV
Sbjct: 1   MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRKV 41


>gi|239745482 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 449

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 24/42 (57%), Positives = 30/42 (71%)

Query: 512 EVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKV 553
           ++VK  IVLTP + SHD    T+ELQ+HVK VT P +Y RKV
Sbjct: 17  QMVKLSIVLTPQFLSHDQSQFTKELQQHVKSVTCPCEYLRKV 58


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,753,462
Number of Sequences: 37866
Number of extensions: 1117314
Number of successful extensions: 2919
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2796
Number of HSP's gapped (non-prelim): 79
length of query: 579
length of database: 18,247,518
effective HSP length: 108
effective length of query: 471
effective length of database: 14,157,990
effective search space: 6668413290
effective search space used: 6668413290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.