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Search of human proteins with 125628665
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|125628665 hypothetical protein LOC388284 [Homo sapiens]
(317 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|125628665 hypothetical protein LOC388284 [Homo sapiens] 633 0.0
gi|30795231 brain abundant, membrane attached signal protein 1 [... 49 8e-06
gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 47 3e-05
gi|169216514 PREDICTED: similar to paraneoplastic antigen MA2 [H... 45 6e-05
gi|169216749 PREDICTED: similar to Putative paraneoplastic antig... 44 2e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 40 0.002
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 40 0.004
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 40 0.004
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 40 0.004
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 40 0.004
gi|92859678 small nuclear RNA activating complex, polypeptide 4,... 40 0.004
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 39 0.005
gi|31543392 peroxisome proliferator-activated receptor gamma, co... 39 0.006
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 39 0.008
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 38 0.014
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 38 0.014
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 37 0.018
gi|157671951 solute carrier family 4, anion exchanger, member 3 ... 37 0.018
gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens] 37 0.023
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 37 0.030
gi|21735548 centrosomal protein 2 [Homo sapiens] 36 0.039
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 36 0.039
gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens] 36 0.039
gi|47132587 protein kinase C, delta binding protein [Homo sapiens] 36 0.051
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 36 0.051
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 36 0.051
gi|14149805 hypothetical protein LOC84080 [Homo sapiens] 36 0.051
gi|24431933 reticulon 4 isoform B [Homo sapiens] 35 0.067
gi|47519490 reticulon 4 isoform D [Homo sapiens] 35 0.067
gi|24431935 reticulon 4 isoform A [Homo sapiens] 35 0.067
>gi|125628665 hypothetical protein LOC388284 [Homo sapiens]
Length = 317
Score = 633 bits (1633), Expect = 0.0
Identities = 317/317 (100%), Positives = 317/317 (100%)
Query: 1 MASAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPA 60
MASAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPA
Sbjct: 1 MASAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPA 60
Query: 61 GAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRA 120
GAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRA
Sbjct: 61 GAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRA 120
Query: 121 HLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLET 180
HLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLET
Sbjct: 121 HLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLET 180
Query: 181 LRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPL 240
LRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPL
Sbjct: 181 LRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPL 240
Query: 241 AGELGPGLALPCPSPLVTPTHALAPLGEEAGEEPGGLPSLGVSDHKAEVDKSTQVDIDKM 300
AGELGPGLALPCPSPLVTPTHALAPLGEEAGEEPGGLPSLGVSDHKAEVDKSTQVDIDKM
Sbjct: 241 AGELGPGLALPCPSPLVTPTHALAPLGEEAGEEPGGLPSLGVSDHKAEVDKSTQVDIDKM 300
Query: 301 LSVCTAPLVPPLSPQYK 317
LSVCTAPLVPPLSPQYK
Sbjct: 301 LSVCTAPLVPPLSPQYK 317
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 48.5 bits (114), Expect = 8e-06
Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 12/150 (8%)
Query: 20 QGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASESELQEEGPKLGEER 79
+G TEE G+ + SE A + PA G + DQ G A E E +++ EE
Sbjct: 27 EGAATEEEGTPKESEPQAAAE----PAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEA 82
Query: 80 PKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPP---KLPLQE 136
PK A E+ + P P+++ G A AEA P P
Sbjct: 83 PK----AEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAG 138
Query: 137 EEPEDSQSEPSPS-AKQHKKAKKRKSLGAP 165
EEP + EP + A A++ KS GAP
Sbjct: 139 EEPSKEEGEPKKTEAPAAPAAQETKSDGAP 168
Score = 30.0 bits (66), Expect = 2.8
Identities = 39/179 (21%), Positives = 62/179 (34%), Gaps = 15/179 (8%)
Query: 2 ASAGAERRPGVQEATVVGQGQLTEEPG----SAQTSECPVAGDQFLVPAHEARGTQSEDQ 57
A+ AE + G ++ +G+ E+ G +A E P A + A EA+ +
Sbjct: 45 AAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAP 104
Query: 58 RPAGAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRH-----GPKRKPVKS 112
AA E PK E P A G P P+ P + KS
Sbjct: 105 EQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKS 164
Query: 113 LSLPGLRAHLKAEAELP--PKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHA 169
P + + P + P E P + P+A A++ K + AP ++
Sbjct: 165 DGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAA----SAEEPKPVEAPAANS 219
>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
Length = 1059
Score = 46.6 bits (109), Expect = 3e-05
Identities = 63/268 (23%), Positives = 98/268 (36%), Gaps = 45/268 (16%)
Query: 71 EGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPP 130
EGP G K G+ + R + PR G +R PG+ A AE P
Sbjct: 465 EGP--GRAESKESVGS-RDSSKREGLLATHPRPGQER--------PGVARKEPARAEAPR 513
Query: 131 KLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRL 190
K + + P + + +P PS + + + R++ +V ++ + RKA
Sbjct: 514 KTEKEAKTPRELKKDPKPSVSRTQPREVRRAAS-----SVPNLKKTNAQAAPKPRKAPST 568
Query: 191 -------------RPLYQYVNYCNPELNQAGKGDGEAEVEAEAELAPVP--EEGGVEQLQ 235
P +P G + EL P+P EE +E
Sbjct: 569 SHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALE--- 625
Query: 236 ALLPLAGELGPGLALPCPSPLVTPTH-----ALAPL-GEEAGEEPG---GLPSLGVSDHK 286
LPLA P P P +P +L+PL G EAG + P++
Sbjct: 626 --LPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLP 683
Query: 287 AEVDKSTQVDIDKMLSVCTAPLVPPLSP 314
AEV ++D+ LSV ++PP +P
Sbjct: 684 AEVGSPHSTEVDESLSVSFEQVLPPSAP 711
>gi|169216514 PREDICTED: similar to paraneoplastic antigen MA2 [Homo
sapiens]
Length = 340
Score = 45.4 bits (106), Expect = 6e-05
Identities = 55/184 (29%), Positives = 78/184 (42%), Gaps = 19/184 (10%)
Query: 3 SAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPV---AGDQFLVPAHEARGTQSEDQRP 59
+AGA G A G+ + T E GSA +E AGD+ V A EAR +
Sbjct: 123 AAGAAGAIGETGAVGKGEAEATGEGGSASEAEGAGEGGAGDELRV-AEEARESDEGAAGD 181
Query: 60 AGAASESELQEEGPKLGEERPKPHAGAL-EERGPRPVVSIVRPRHGPKRKPVKSLSLPGL 118
G A E+E E +GE AGA+ E RG + V+PR + +++ + L
Sbjct: 182 TGPAGEAEAVGEAGAVGEAGAAGEAGAVGEARGTNVTRAWVQPRRCTLQAVLENRAYQEL 241
Query: 119 RAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQ---HKKAKKRK-----SLGAPVLHAV 170
R E P EEE +S E + Q H ++RK SLG P L V
Sbjct: 242 RPFSGREQ------PGCEEESFESWMEHAKDMLQLWYHASERERKRWLLESLGGPALDVV 295
Query: 171 ASMV 174
+ ++
Sbjct: 296 SGLL 299
>gi|169216749 PREDICTED: similar to Putative paraneoplastic
antigen-like protein 6B-like protein [Homo sapiens]
Length = 340
Score = 43.9 bits (102), Expect = 2e-04
Identities = 54/184 (29%), Positives = 78/184 (42%), Gaps = 19/184 (10%)
Query: 3 SAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPV---AGDQFLVPAHEARGTQSEDQRP 59
+AGA G A G+ + T E GSA +E AGD+ V A EAR +
Sbjct: 123 AAGAAGAIGETGAVGKGEAEATGEGGSASEAEGAGEGGAGDELRV-AEEARESDEGAAGD 181
Query: 60 AGAASESELQEEGPKLGEERPKPHAGAL-EERGPRPVVSIVRPRHGPKRKPVKSLSLPGL 118
G A E+E E +GE AGA+ E RG + V+PR + +++ + L
Sbjct: 182 TGPAGEAEAVGEAGAVGEAGAAGEAGAVGEARGTNVTRAWVQPRRCTLQAVLENRAYQEL 241
Query: 119 RAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQ---HKKAKKRK-----SLGAPVLHAV 170
R E P +EE +S E + Q H ++RK SLG P L V
Sbjct: 242 RPFSGREQ------PGCKEESFESWMEHAKDMLQLWYHASERERKRWLLESLGGPALDVV 295
Query: 171 ASMV 174
+ ++
Sbjct: 296 SGLL 299
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 40.4 bits (93), Expect = 0.002
Identities = 86/322 (26%), Positives = 117/322 (36%), Gaps = 66/322 (20%)
Query: 24 TEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASESELQEE--GPKLGEERPK 81
TEEP + E P Q P QSE+ + ES L E P L K
Sbjct: 810 TEEPHLSPVPEEPCLSPQ---PEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK 866
Query: 82 PHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPED 141
P EE G P + P P +P SLS P L +E PP PL EE P
Sbjct: 867 PP----EEPGQCPAPEEL-PLFPPPGEP--SLS-PLLGEPALSEPGEPPLSPLPEELPLS 918
Query: 142 SQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLYQYVNYCN 201
EPS S + L +P++ A A +PL L A+
Sbjct: 919 PSGEPSLSPQLMPPDPLPPPL-SPIITAAAPPALSPLGELEYPFGAK------------- 964
Query: 202 PELNQAGKGDGEAEVEA---EAELAPVPEEGGVEQLQA---LLPLA-----GELGPGLAL 250
G D E+ + A E ++P PE + +LP + G P L
Sbjct: 965 ------GDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILME 1018
Query: 251 PCP---SPLVTPTHALAPLGEEAGE-EPGGLP------------SLGVSD----HKAEVD 290
P P SPL+ H+L P + P LP +GVSD H+ E +
Sbjct: 1019 PLPPQCSPLL--QHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETE 1076
Query: 291 KSTQVDIDKMLSVCTAPLVPPL 312
K ++ + + T+PL P+
Sbjct: 1077 KVSEPECPALEPSATSPLPSPM 1098
Score = 32.3 bits (72), Expect = 0.57
Identities = 36/117 (30%), Positives = 47/117 (40%), Gaps = 28/117 (23%)
Query: 73 PKLGEERPKPHAGALEE--RGPRP-----------------VVSIVRPRHGPK--RKPVK 111
P+LG P P G L+E GPRP V+ V P P ++P +
Sbjct: 4261 PQLGGF-PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR 4319
Query: 112 SLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEP-----SPSAKQHKKAKKRKSLG 163
LP + L EA+LPP P +P+ EP SP+A Q K LG
Sbjct: 4320 PSQLPSPSSQLPTEAQLPPTHP-GTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLG 4375
Score = 30.0 bits (66), Expect = 2.8
Identities = 64/267 (23%), Positives = 93/267 (34%), Gaps = 47/267 (17%)
Query: 25 EEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASE----SELQEEGPKLGEERP 80
E P S E P + P +R + ++ PA E S EE P P
Sbjct: 446 ESPLSPPPEESPTSP-----PPEASRLSPPPEELPASPLPEALHLSRPLEESPL----SP 496
Query: 81 KPHAGALEERGPRPVVSIVRP-RHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEE- 138
P L P P S P P P +S P L L E P P EE
Sbjct: 497 PPEESPLS---PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP 553
Query: 139 ----PEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLY 194
PE+ + P P A + + + P S +S P E A RL P +
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPP---PEESPMSPPPE-------ASRLFPPF 603
Query: 195 QYVNYCNP----ELNQAGKGDGEAEVEAEAELAPVPEEGGVE---QLQALLPLAGELGPG 247
+ P L+ + + ++ ++P PEE + ++ L PL P
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL-----PV 658
Query: 248 LALPCPSPLVTPTHALAPLGEEAGEEP 274
++ P P +P L+P EE+ P
Sbjct: 659 VSRLSPPPEESP---LSPPPEESPTSP 682
Score = 28.5 bits (62), Expect = 8.2
Identities = 46/181 (25%), Positives = 67/181 (37%), Gaps = 30/181 (16%)
Query: 96 VSIVRPRH-GPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHK 154
V+ ++P+ GP + K L G++ + EA L ++PL PE+S P P
Sbjct: 401 VTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLL-PPPEESPLSPPPEESPTS 459
Query: 155 KAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEA 214
+ L P AS + E L L RPL + PE
Sbjct: 460 PPPEASRLSPPPEELPASPLP---EALHLS------RPLEESPLSPPPE----------- 499
Query: 215 EVEAEAELAPVPEEGGVEQL-QALLPLAGELGPGLALPCPSPLVTPTHALAPLGEEAGEE 273
E+ L+P PE L ++ L E P AL P ++P +PL E
Sbjct: 500 ----ESPLSPPPESSPFSPLEESPLSPPEESPPSPALETP---LSPPPEASPLSPPFEES 552
Query: 274 P 274
P
Sbjct: 553 P 553
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 39.7 bits (91), Expect = 0.004
Identities = 87/361 (24%), Positives = 128/361 (35%), Gaps = 84/361 (23%)
Query: 5 GAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAAS 64
GA +PG+ A GQ + E S+ + E V G + PA + S + PA A+
Sbjct: 183 GAAAKPGMVSA---GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAA 239
Query: 65 ESELQEEGPKLGEERPKPHAGAL----------------------EERGPRPVVSIVRPR 102
+ K+G+ P+ GAL EE P S V+
Sbjct: 240 PAP-----GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA- 293
Query: 103 HGPKRKPVKSLSLPGLRAHLKAEAELPP----------KLPLQEEEPEDSQSEPS----- 147
K V++ S P K PP K EE+ E S E S
Sbjct: 294 -SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352
Query: 148 -PSAK---QHKKAKKRKSLGAPVLHAVAS-----MVSAPLETLRLERKAQRLRPLYQYVN 198
P+AK Q K + K +GA A S + P +T KAQ +
Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK------- 405
Query: 199 YCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPLAGELGPGLALPCPSPLVT 258
E +Q+ + ++E EA A+ P G Q++A A E A P P
Sbjct: 406 --REEDSQSSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAAPAPPRKTG 460
Query: 259 PTHALAPLGEEAGEEPGGLPSLGVSDHKAEVDKSTQVDIDKMLSVCTAPLVPPL--SPQY 316
P A +G++ + S +++ D+ + L+ A V PL SPQ
Sbjct: 461 PAAAQVQVGKQEEDSRS-------SSEESDSDR-------EALAAMNAAQVKPLGKSPQV 506
Query: 317 K 317
K
Sbjct: 507 K 507
Score = 29.6 bits (65), Expect = 3.7
Identities = 54/266 (20%), Positives = 89/266 (33%), Gaps = 40/266 (15%)
Query: 3 SAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAG---DQFLVPAHEARGTQSEDQRP 59
+A R+ E+T +E+ ++C G + +P R
Sbjct: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
Query: 60 AGAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLR 119
A ++ ES +G K +E P + G P S P+ V++ LR
Sbjct: 1040 ASSSKESSRISDGKK--QEGPATQVDSAV--GTLPATS-------PQSTSVQAKGTNKLR 1088
Query: 120 AHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQ---HKKAKKRKSLGAPVLHAVASMVS- 175
E + K P ++ EDS S S + + AK +L P ++V
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE 1148
Query: 176 -----------APLETLRLERKAQRLRPLYQYVNYCNPELNQ--------AGKGDGEAEV 216
AP ++L L P + P+L+ A K D + +
Sbjct: 1149 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1208
Query: 217 EAEAELAP---VPEEGGVEQLQALLP 239
EA+ + A P+ GG E P
Sbjct: 1209 EAKPQQAAGMLSPKTGGKEAASGTTP 1234
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 39.7 bits (91), Expect = 0.004
Identities = 87/361 (24%), Positives = 128/361 (35%), Gaps = 84/361 (23%)
Query: 5 GAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAAS 64
GA +PG+ A GQ + E S+ + E V G + PA + S + PA A+
Sbjct: 183 GAAAKPGMVSA---GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAA 239
Query: 65 ESELQEEGPKLGEERPKPHAGAL----------------------EERGPRPVVSIVRPR 102
+ K+G+ P+ GAL EE P S V+
Sbjct: 240 PAP-----GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA- 293
Query: 103 HGPKRKPVKSLSLPGLRAHLKAEAELPP----------KLPLQEEEPEDSQSEPS----- 147
K V++ S P K PP K EE+ E S E S
Sbjct: 294 -SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352
Query: 148 -PSAK---QHKKAKKRKSLGAPVLHAVAS-----MVSAPLETLRLERKAQRLRPLYQYVN 198
P+AK Q K + K +GA A S + P +T KAQ +
Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK------- 405
Query: 199 YCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPLAGELGPGLALPCPSPLVT 258
E +Q+ + ++E EA A+ P G Q++A A E A P P
Sbjct: 406 --REEDSQSSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAAPAPPRKTG 460
Query: 259 PTHALAPLGEEAGEEPGGLPSLGVSDHKAEVDKSTQVDIDKMLSVCTAPLVPPL--SPQY 316
P A +G++ + S +++ D+ + L+ A V PL SPQ
Sbjct: 461 PAAAQVQVGKQEEDSRS-------SSEESDSDR-------EALAAMNAAQVKPLGKSPQV 506
Query: 317 K 317
K
Sbjct: 507 K 507
Score = 28.9 bits (63), Expect = 6.3
Identities = 50/219 (22%), Positives = 78/219 (35%), Gaps = 30/219 (13%)
Query: 48 EARGTQSEDQRPAGAA-SESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPK 106
E TQ + PA +++ L+ K E +P P A G V + P P+
Sbjct: 1056 EGPATQVSKKNPASLPLTQAALKVLAQKASEAQP-PVARTQPSSGVDSAVGTL-PATSPQ 1113
Query: 107 RKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQ---HKKAKKRKSLG 163
V++ LR E + K P ++ EDS S S + + AK +LG
Sbjct: 1114 STSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLG 1173
Query: 164 APVLHAVASMVS------------APLETLRLERKAQRLRPLYQYVNYCNPELNQ----- 206
P ++V AP ++L L P + P+L+
Sbjct: 1174 -PTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVS 1232
Query: 207 ---AGKGDGEAEVEAEAELAP---VPEEGGVEQLQALLP 239
A K D + + EA+ + A P+ GG E P
Sbjct: 1233 STLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTP 1271
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 39.7 bits (91), Expect = 0.004
Identities = 87/361 (24%), Positives = 128/361 (35%), Gaps = 84/361 (23%)
Query: 5 GAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAAS 64
GA +PG+ A GQ + E S+ + E V G + PA + S + PA A+
Sbjct: 183 GAAAKPGMVSA---GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAA 239
Query: 65 ESELQEEGPKLGEERPKPHAGAL----------------------EERGPRPVVSIVRPR 102
+ K+G+ P+ GAL EE P S V+
Sbjct: 240 PAP-----GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA- 293
Query: 103 HGPKRKPVKSLSLPGLRAHLKAEAELPP----------KLPLQEEEPEDSQSEPS----- 147
K V++ S P K PP K EE+ E S E S
Sbjct: 294 -SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352
Query: 148 -PSAK---QHKKAKKRKSLGAPVLHAVAS-----MVSAPLETLRLERKAQRLRPLYQYVN 198
P+AK Q K + K +GA A S + P +T KAQ +
Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK------- 405
Query: 199 YCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPLAGELGPGLALPCPSPLVT 258
E +Q+ + ++E EA A+ P G Q++A A E A P P
Sbjct: 406 --REEDSQSSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAAPAPPRKTG 460
Query: 259 PTHALAPLGEEAGEEPGGLPSLGVSDHKAEVDKSTQVDIDKMLSVCTAPLVPPL--SPQY 316
P A +G++ + S +++ D+ + L+ A V PL SPQ
Sbjct: 461 PAAAQVQVGKQEEDSRS-------SSEESDSDR-------EALAAMNAAQVKPLGKSPQV 506
Query: 317 K 317
K
Sbjct: 507 K 507
Score = 28.5 bits (62), Expect = 8.2
Identities = 55/266 (20%), Positives = 90/266 (33%), Gaps = 41/266 (15%)
Query: 3 SAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAG---DQFLVPAHEARGTQSEDQRP 59
+A R+ E+T +E+ ++C G + +P R
Sbjct: 980 AASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAG 1039
Query: 60 AGAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLR 119
A ++ ES +G K +E P + G P S P+ V++ LR
Sbjct: 1040 ASSSKESSRISDGKK--QEGPATQVDSAV--GTLPATS-------PQSTSVQAKGTNKLR 1088
Query: 120 AHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQ---HKKAKKRKSLGAPVLHAVASMVS- 175
E + K P ++ EDS S S + + AK +LG P ++V
Sbjct: 1089 KPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLG-PTPSRTETLVEE 1147
Query: 176 -----------APLETLRLERKAQRLRPLYQYVNYCNPELNQ--------AGKGDGEAEV 216
AP ++L L P + P+L+ A K D + +
Sbjct: 1148 TAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQ 1207
Query: 217 EAEAELAP---VPEEGGVEQLQALLP 239
EA+ + A P+ GG E P
Sbjct: 1208 EAKPQQAAGMLSPKTGGKEAASGTTP 1233
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 39.7 bits (91), Expect = 0.004
Identities = 87/361 (24%), Positives = 128/361 (35%), Gaps = 84/361 (23%)
Query: 5 GAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAAS 64
GA +PG+ A GQ + E S+ + E V G + PA + S + PA A+
Sbjct: 183 GAAAKPGMVSA---GQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAA 239
Query: 65 ESELQEEGPKLGEERPKPHAGAL----------------------EERGPRPVVSIVRPR 102
+ K+G+ P+ GAL EE P S V+
Sbjct: 240 PAP-----GKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA- 293
Query: 103 HGPKRKPVKSLSLPGLRAHLKAEAELPP----------KLPLQEEEPEDSQSEPS----- 147
K V++ S P K PP K EE+ E S E S
Sbjct: 294 -SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352
Query: 148 -PSAK---QHKKAKKRKSLGAPVLHAVAS-----MVSAPLETLRLERKAQRLRPLYQYVN 198
P+AK Q K + K +GA A S + P +T KAQ +
Sbjct: 353 TPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGK------- 405
Query: 199 YCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPLAGELGPGLALPCPSPLVT 258
E +Q+ + ++E EA A+ P G Q++A A E A P P
Sbjct: 406 --REEDSQSSSEESDSEEEAPAQAKP---SGKAPQVRAASAPAKESPRKGAAPAPPRKTG 460
Query: 259 PTHALAPLGEEAGEEPGGLPSLGVSDHKAEVDKSTQVDIDKMLSVCTAPLVPPL--SPQY 316
P A +G++ + S +++ D+ + L+ A V PL SPQ
Sbjct: 461 PAAAQVQVGKQEEDSRS-------SSEESDSDR-------EALAAMNAAQVKPLGKSPQV 506
Query: 317 K 317
K
Sbjct: 507 K 507
>gi|92859678 small nuclear RNA activating complex, polypeptide 4,
190kDa [Homo sapiens]
Length = 1469
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/178 (24%), Positives = 63/178 (35%), Gaps = 9/178 (5%)
Query: 10 PGVQEATVVGQGQLT---EEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASES 66
P +A +G GQ++ E G Q S+ P A + +P + P S
Sbjct: 1001 PAASQAPALGPGQISVSCPESGLGQ-SQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLS 1059
Query: 67 ELQEEGPKLGEERPKPHAGALEERGPRPV-----VSIVRPRHGPKRKPVKSLSLPGLRAH 121
GP + P P L +G PV VS+ RP P + + LP L
Sbjct: 1060 LTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTET 1119
Query: 122 LKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLE 179
A+ P L + P + EP PS + A +L A S+ P E
Sbjct: 1120 RAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGE 1177
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 39.3 bits (90), Expect = 0.005
Identities = 74/296 (25%), Positives = 109/296 (36%), Gaps = 57/296 (19%)
Query: 51 GTQSEDQRPAGAASESELQEEGPK--LGEERPKPHAGALEERGPRPVVSIVRPRH----- 103
G S P A + L ++ P L +RP P PRPV RP
Sbjct: 1116 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPP---------PRPVAPPTRPAPPQRPP 1166
Query: 104 --------GPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKK 155
P RK + P + E E P K P + +S+PSP A
Sbjct: 1167 PPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP-KSPGTTRKDNIGRSQPSPQAGLAGP 1225
Query: 156 AKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEAE 215
S P + A ++SAP R A RL P Q + ++ KG
Sbjct: 1226 GPAGYSTARPTIPPRAGVISAPQSHAR--ASAGRLTPESQ------SKTSETSKGSTFLP 1277
Query: 216 VEAEAELAPVPEEG---GVEQLQ-ALLPLAGEL---GPGLAL---PCPSPLVTPTHALAP 265
+ + A P+ ++LQ L+P+A + GP L P P P +H+L
Sbjct: 1278 EPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP- 1336
Query: 266 LGEEAGEEPGGLPSLGVSDHKAE----VDKSTQVDIDKM------LSVCTAPLVPP 311
EA +P + + G+SD K E +D + + + LSV T+P+ P
Sbjct: 1337 --SEASSQP-QVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTP 1389
>gi|31543392 peroxisome proliferator-activated receptor gamma,
coactivator 1 beta [Homo sapiens]
Length = 1023
Score = 38.9 bits (89), Expect = 0.006
Identities = 48/185 (25%), Positives = 69/185 (37%), Gaps = 16/185 (8%)
Query: 79 RPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEE 138
RP+P + G V VR PK + SL LR +K E P +L QEEE
Sbjct: 374 RPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRP-SLRPLRLEVKREVRRPARLQQQEEE 432
Query: 139 PE--DSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLYQY 196
E + + E ++ + +KR G P + S+ R R L P +
Sbjct: 433 DEEEEEEEEEEEKEEEEEWGRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWLTF 492
Query: 197 VNYCNPELNQAGKGD------GEAEVEAEAEL-APVPEEGGVEQLQALLPLAGELGPGLA 249
+ P + +G + E EL +P E+ G +Q L G P L
Sbjct: 493 AD--EPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQL----LRGPQIPALE 546
Query: 250 LPCPS 254
PC S
Sbjct: 547 SPCES 551
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 38.5 bits (88), Expect = 0.008
Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 17/119 (14%)
Query: 48 EARGTQSEDQRPAGAASESELQEEGPKLGEER-PKPHAGALEERGPRPVVSIVRPRHGPK 106
E++ + E +R +S+ + KLGE R PK EE+ P P + P+ K
Sbjct: 210 ESKSSSKELEREQAKSSK----DTSRKLGEGRLPK------EEKAPPPKAAFKEPKMALK 259
Query: 107 RKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAP 165
++S S G PP P + + P PSAK+ KK+ + S AP
Sbjct: 260 ETKLESTSPKG------GPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAP 312
Score = 29.3 bits (64), Expect = 4.8
Identities = 34/158 (21%), Positives = 53/158 (33%), Gaps = 24/158 (15%)
Query: 9 RPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASESEL 68
RP + +L E + G+ L +A ++ + P A E++L
Sbjct: 204 RPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKL 263
Query: 69 QEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVK----------SLSLPGL 118
+ PK G P P P P S RP KP S S PG
Sbjct: 264 ESTSPKGGPPPPPP---------PPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGT 314
Query: 119 RAHLKAEAELPPKLPLQEE-----EPEDSQSEPSPSAK 151
+ + K P +++ E ++SEP + K
Sbjct: 315 SPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKK 352
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 37.7 bits (86), Expect = 0.014
Identities = 63/237 (26%), Positives = 89/237 (37%), Gaps = 38/237 (16%)
Query: 51 GTQSEDQRPAGAASESELQEEGPK--LGEERPKPHAGALEERGPRPVVSIVRPRHGPKRK 108
G S P A + L ++ P L +RP P PRPV RP P+R
Sbjct: 1077 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPP---------PRPVAPPTRPAP-PQRP 1126
Query: 109 PVKSLSLPGLRAHLKAEAEL-PPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVL 167
P S G R+ E PK P + +S+PSP A S P +
Sbjct: 1127 PPPS----GARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTI 1182
Query: 168 HAVASMVSAPLETLRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEAEVEAEAELAPVPE 227
A ++SAP R A RL P Q + ++ KG + + A P+
Sbjct: 1183 PPRAGVISAPQSHAR--ASAGRLTPESQ------SKTSETSKGSTFLPEPLKPQAAFPPQ 1234
Query: 228 EG---GVEQLQ-ALLPLAGEL---GPGLAL---PCPSPLVTPTHALAPLGEEAGEEP 274
++LQ L+P+A + GP L P P P +H+L EA +P
Sbjct: 1235 SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP---SEASSQP 1288
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 37.7 bits (86), Expect = 0.014
Identities = 33/106 (31%), Positives = 40/106 (37%), Gaps = 19/106 (17%)
Query: 51 GTQSEDQRPAGAASESELQEEGPK--------LGEERPKPHAGALEERGPRPVVSIVRPR 102
G Q +D RP EL +G LG + G L ERGP
Sbjct: 887 GHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPP--------- 937
Query: 103 HGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSP 148
GP P + LPGL A+ EL P PL +E P + P P
Sbjct: 938 -GPPGPPGEQ-GLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGP 981
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 37.4 bits (85), Expect = 0.018
Identities = 27/118 (22%), Positives = 45/118 (38%), Gaps = 6/118 (5%)
Query: 48 EARGTQSEDQRPAGAASESELQEEGPKLGEERPKPHAGALEERGP---RPVVSIVRPRHG 104
+A T+ + P+ + S P + P P + P +P ++
Sbjct: 912 QAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAANKMPLAQKPALAPKPTSQT 971
Query: 105 PKRKPVKSLSLPGLRAHLKAEAELP---PKLPLQEEEPEDSQSEPSPSAKQHKKAKKR 159
P P+ LS P L L A P P P +E++ + PSP + +K +KR
Sbjct: 972 PPASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESSDRRPPSPPGPEERKGQKR 1029
>gi|157671951 solute carrier family 4, anion exchanger, member 3
isoform 1 [Homo sapiens]
Length = 1232
Score = 37.4 bits (85), Expect = 0.018
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 12/131 (9%)
Query: 44 VPAHEARGTQSEDQRPAGAASESE----LQEEGPKLGEERPKPHAGALEERGPRPVVSIV 99
+P AR T+ + ++ +A SE +QEEG +E + EE G +
Sbjct: 98 LPPTSARHTRRKRKKEKTSAPPSEGTPPIQEEGGAGVDEEEEEEE---EEEGESEAEPVE 154
Query: 100 RPRHGPKRKPVKSLSL-----PGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHK 154
P G +K S+ PGL LP P ++ P+ S S PSP A+ +
Sbjct: 155 PPPSGTPQKAKFSIGSDEDDSPGLPGRAAVTKPLPSVGPHTDKSPQHSSSSPSPRARASR 214
Query: 155 KAKKRKSLGAP 165
A ++ +P
Sbjct: 215 LAGEKSRPWSP 225
>gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens]
Length = 3996
Score = 37.0 bits (84), Expect = 0.023
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 5/109 (4%)
Query: 58 RPAGAASESELQEEGPKLGEERPK----PHAGALEERGPRPVVSIVRPRHGPKRKPVKSL 113
RP E +L + K G +PK ++ A +E+ P VVS RP P K L
Sbjct: 3303 RPPKKVLEDQLTQILRKYGVPKPKFDKSKYSKAGKEQHPVKVVSTKRPITKPPAKDKAVL 3362
Query: 114 SLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSL 162
+ A + + + PK P ++ +P++ E SP+ KQ +K +L
Sbjct: 3363 NSVSRTALSEKKPTVKPKSP-EKSKPDEKDPEKSPTKKQEVPEEKYLTL 3410
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 36.6 bits (83), Expect = 0.030
Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 16/106 (15%)
Query: 5 GAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSE-----DQRP 59
G E++ G +E + E G +T E G + + + +GT+ + R
Sbjct: 487 GVEKKGGEEEPEATKEPLEAERKGGEETLEAEKRGGEESLETEKTQGTEGDLNLEQGSRE 546
Query: 60 AGAASESELQEEGPKLG--------EERPKPH---AGALEERGPRP 94
+ E+ E GP L +E P+P GALEE G +P
Sbjct: 547 GSESQAEEMNEAGPPLEANTETRPEKEGPQPQEKPVGALEEEGVKP 592
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 36.2 bits (82), Expect = 0.039
Identities = 42/181 (23%), Positives = 80/181 (44%), Gaps = 7/181 (3%)
Query: 52 TQSEDQRPAGAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPK-RKPV 110
+Q+E +R A A ++ ++EG E++ H + + R R H + K +
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQL--REKWEKERSWHQQELAKAL 877
Query: 111 KSLSLPGLRAHLKAEAELPPKLPLQ-EEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHA 169
+SL + ++ + + +Q + E E +Q+E + Q + K+R SL +L
Sbjct: 878 ESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQT 937
Query: 170 VASMVSA--PLETLRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEAEVEAEAELAPVPE 227
+ A LE LR + K Q+L+ + +L +A + EA + +LA + E
Sbjct: 938 QKELADASQQLERLRQDMKVQKLKE-QETTGILQTQLQEAQRELKEAARQHRDDLAALQE 996
Query: 228 E 228
E
Sbjct: 997 E 997
>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
Length = 669
Score = 36.2 bits (82), Expect = 0.039
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 15/112 (13%)
Query: 54 SEDQRPAGAASESELQEEGPKLGEE-RPKPHAGAL-EERGPRPVVSIVRPRHGPKRKPVK 111
SE PA A S P G P+ +G L G RP + RP H P+R+P+
Sbjct: 389 SESSLPAAVAGFSSRHPLSPGFGAAGTPRWRSGGLVHSGGARPGL---RPSHPPRRRPLP 445
Query: 112 SLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLG 163
S G H A+ LPP P D QS PSA + R + G
Sbjct: 446 PASSLG---HPPAKPPLPP-------GPVDMQSFRRPSAASIDLRRTRSAAG 487
Score = 30.8 bits (68), Expect = 1.7
Identities = 41/137 (29%), Positives = 58/137 (42%), Gaps = 15/137 (10%)
Query: 54 SEDQRPAGAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSL 113
SE +R + A + Q ++ P+P G L P VS++ R P+ K+L
Sbjct: 260 SEPKRDSSAFPKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSVLPKR--PRPAEFKAL 317
Query: 114 S-------LPGL-RAHLKAEAELPPKLPLQEEE--PEDSQSEPSPSA--KQHKKAKKRKS 161
S L GL R + E P+ LQ E P S+P PSA K+H + +
Sbjct: 318 SKKPPQPELGGLPRTSSEPEFNSLPRKLLQPERRGPPRKFSQPEPSAVLKRHPQPEFFGD 377
Query: 162 L-GAPVLHAVASMVSAP 177
L P L + AS S P
Sbjct: 378 LPRKPPLPSSASESSLP 394
Score = 29.3 bits (64), Expect = 4.8
Identities = 51/217 (23%), Positives = 75/217 (34%), Gaps = 24/217 (11%)
Query: 18 VGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASESELQEEGPKLGE 77
+G +P + E P+ P AR D+ A SE PK G
Sbjct: 134 LGATPFPRKPLQPEVGEAPLKAS-LPEPGAPARKPLQPDELSHPARPPSE-----PKSGA 187
Query: 78 ERPK---PHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPL 134
K P AG R P+P +S PK+ ++ + LP K
Sbjct: 188 FPRKLWQPEAGEATPRSPQPELSTF-----PKKPAQPEFNVYPKKPPQPQVGGLPKK--- 239
Query: 135 QEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLY 194
+PE S++ +P K KR S P PL + L L
Sbjct: 240 SVPQPEFSEAAQTPLWKPQSSEPKRDSSAFP-----KKASQPPLSDFPKKPPQPELGDLT 294
Query: 195 QYVNYCNPELNQAGKGDGEAEVEAEAELAPVPEEGGV 231
+ + PE++ K AE +A ++ P PE GG+
Sbjct: 295 RTSS--EPEVSVLPKRPRPAEFKALSKKPPQPELGGL 329
>gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens]
Length = 473
Score = 36.2 bits (82), Expect = 0.039
Identities = 42/151 (27%), Positives = 62/151 (41%), Gaps = 28/151 (18%)
Query: 16 TVVGQGQLTEEPGSAQTSECPVAGD--------QFLVPAHEARGTQSEDQRPAGAASESE 67
T V TE P S +E PV G+ Q V E + +D G+A+ S+
Sbjct: 178 TPVQSSASTESPAS---TESPVGGEGSELGEVLQIQVEEEEEE-EEDDDDEDQGSATLSQ 233
Query: 68 LQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAE 127
+ ++ P+PH GP P+ PR P+ + L LP A
Sbjct: 234 TPQP-QRVSGVFPRPH-------GPHPLPMTATPRKLPEGESAP-LELP-------APPA 277
Query: 128 LPPKLPLQEEEPEDSQSEPSPSAKQHKKAKK 158
LPPK+ ++EP + + E S S Q AK+
Sbjct: 278 LPPKIFYIKQEPFEPKEEISGSGTQPGGAKE 308
>gi|47132587 protein kinase C, delta binding protein [Homo sapiens]
Length = 261
Score = 35.8 bits (81), Expect = 0.051
Identities = 32/101 (31%), Positives = 44/101 (43%), Gaps = 13/101 (12%)
Query: 59 PAGAASESELQEE------GPKLGEERPKPHAGALEERGPRPVVSIVRPRHG------PK 106
P G A +SEL E G EE + A L G + V S+ R G P
Sbjct: 144 PLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRRTGLQKVQSLRRALSGRKGPAAPP 203
Query: 107 RKPVKSLSL-PGLRAHLKAEAELPPKLPLQEEEPEDSQSEP 146
PVK L PG A + EA+ + L+ E P+D++ +P
Sbjct: 204 PTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDTEEDP 244
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 35.8 bits (81), Expect = 0.051
Identities = 45/215 (20%), Positives = 76/215 (35%), Gaps = 26/215 (12%)
Query: 19 GQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASESELQEEGPKLGEE 78
GQ + EE A++ + G + + + G Q E + A A E +E K+ E
Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE- 590
Query: 79 RPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEE 138
K A +E + +P P + G K+ E K P+ +
Sbjct: 591 --KSEEVATKEELVADA-KVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 647
Query: 139 PEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLYQYVN 198
E+ P P + +K K S A + + +P+E +
Sbjct: 648 VEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK---------------- 691
Query: 199 YCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQ 233
++A G GE + E E E+ P+E VE+
Sbjct: 692 ------SKAEVGKGEQKEEEEKEVKEAPKEEKVEK 720
Score = 28.5 bits (62), Expect = 8.2
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 203 ELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPLAGELGPGLALPCPSPLVTPTHA 262
E + + +GE E EAE E A EE VE+ + E+ L + + P A
Sbjct: 560 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEE------KSEEVATKEELVADAKVEKPEKA 613
Query: 263 LAPLGEEAGEEPGGLP 278
+P+ + EE G P
Sbjct: 614 KSPVPKSPVEEKGKSP 629
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 35.8 bits (81), Expect = 0.051
Identities = 45/215 (20%), Positives = 76/215 (35%), Gaps = 26/215 (12%)
Query: 19 GQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASESELQEEGPKLGEE 78
GQ + EE A++ + G + + + G Q E + A A E +E K+ E
Sbjct: 156 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE- 214
Query: 79 RPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEE 138
K A +E + +P P + G K+ E K P+ +
Sbjct: 215 --KSEEVATKEELVADA-KVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 271
Query: 139 PEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLYQYVN 198
E+ P P + +K K S A + + +P+E +
Sbjct: 272 VEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK---------------- 315
Query: 199 YCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQ 233
++A G GE + E E E+ P+E VE+
Sbjct: 316 ------SKAEVGKGEQKEEEEKEVKEAPKEEKVEK 344
Score = 28.5 bits (62), Expect = 8.2
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 203 ELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPLAGELGPGLALPCPSPLVTPTHA 262
E + + +GE E EAE E A EE VE+ + E+ L + + P A
Sbjct: 184 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEE------KSEEVATKEELVADAKVEKPEKA 237
Query: 263 LAPLGEEAGEEPGGLP 278
+P+ + EE G P
Sbjct: 238 KSPVPKSPVEEKGKSP 253
>gi|14149805 hypothetical protein LOC84080 [Homo sapiens]
Length = 346
Score = 35.8 bits (81), Expect = 0.051
Identities = 60/262 (22%), Positives = 100/262 (38%), Gaps = 62/262 (23%)
Query: 77 EERPKPHAGALEERGPRPVVSIVR-PRHGPKRKPVKS-LSLPG----------LRAHLKA 124
++R + + E+ PRP+ ++ R P++ VK+ L PG LRAH +
Sbjct: 112 QKRFREQERSREQGQPRPLKALWRSPKYDKVESRVKAQLQEPGPASGTESAHFLRAHSRC 171
Query: 125 EAELPPKLPLQEEEPEDSQSEPSPSAKQHKKA---------KKRKSLGAPVLHAVASMVS 175
LPP P S +P+P + K+ R + AP H+ + V
Sbjct: 172 GPGLPP--------PHVSSPQPTPPGPEAKEPGLGVDFIRHNARAAKRAPRRHSCSLQVL 223
Query: 176 APLETLRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEAEVEAEAELAP--------VPE 227
A + L +R+AQ Q + + L + EAE +++ P +PE
Sbjct: 224 A--QVLEQQRQAQEHYNATQKGHVPHYLLERRDLWRREAEARKQSQPDPAMPPGHTRMPE 281
Query: 228 EGGVEQLQALLPLAGELGPGLALPCPSPLVTPTHALAPLGEEAGEEPGGLPSLGVSDHKA 287
+E L LL +L L L P G SL H+A
Sbjct: 282 NQRLETLTKLLQSQSQLLRELVLL----------------------PAGADSLRAQSHRA 319
Query: 288 EVDKSTQVDIDKMLSVCTAPLV 309
E+D+ V +++ + + + P V
Sbjct: 320 ELDRKL-VQVEEAIKIFSRPKV 340
>gi|24431933 reticulon 4 isoform B [Homo sapiens]
Length = 373
Score = 35.4 bits (80), Expect = 0.067
Identities = 40/148 (27%), Positives = 52/148 (35%), Gaps = 17/148 (11%)
Query: 45 PAHEARGTQSEDQRPAGAASESELQEEGPKLG-EERPKPHAGAL--------------EE 89
P E + E++ E E+ E P G P P A A
Sbjct: 31 PEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAP 90
Query: 90 RGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPS 149
RGP P V P P P S + L A A P KLP +E P ++ P P
Sbjct: 91 RGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPP--ARPPPPPP 148
Query: 150 AKQHKKAKKRKSLGAPVLHAVASMVSAP 177
A +A+ + AP A S +AP
Sbjct: 149 ASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
>gi|47519490 reticulon 4 isoform D [Homo sapiens]
Length = 392
Score = 35.4 bits (80), Expect = 0.067
Identities = 40/148 (27%), Positives = 52/148 (35%), Gaps = 17/148 (11%)
Query: 45 PAHEARGTQSEDQRPAGAASESELQEEGPKLG-EERPKPHAGAL--------------EE 89
P E + E++ E E+ E P G P P A A
Sbjct: 31 PEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAP 90
Query: 90 RGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPS 149
RGP P V P P P S + L A A P KLP +E P ++ P P
Sbjct: 91 RGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPP--ARPPPPPP 148
Query: 150 AKQHKKAKKRKSLGAPVLHAVASMVSAP 177
A +A+ + AP A S +AP
Sbjct: 149 ASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 35.4 bits (80), Expect = 0.067
Identities = 40/148 (27%), Positives = 52/148 (35%), Gaps = 17/148 (11%)
Query: 45 PAHEARGTQSEDQRPAGAASESELQEEGPKLG-EERPKPHAGAL--------------EE 89
P E + E++ E E+ E P G P P A A
Sbjct: 31 PEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAP 90
Query: 90 RGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPS 149
RGP P V P P P S + L A A P KLP +E P ++ P P
Sbjct: 91 RGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPP--ARPPPPPP 148
Query: 150 AKQHKKAKKRKSLGAPVLHAVASMVSAP 177
A +A+ + AP A S +AP
Sbjct: 149 ASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.129 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,372,208
Number of Sequences: 37866
Number of extensions: 920752
Number of successful extensions: 4516
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 296
Number of HSP's that attempted gapping in prelim test: 4202
Number of HSP's gapped (non-prelim): 600
length of query: 317
length of database: 18,247,518
effective HSP length: 102
effective length of query: 215
effective length of database: 14,385,186
effective search space: 3092814990
effective search space used: 3092814990
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.