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Search of human proteins with 12545395
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12545395 islet cell autoantigen 1 [Homo sapiens]
(483 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209862841 islet cell autoantigen 1 [Homo sapiens] 972 0.0
gi|94721350 islet cell autoantigen 1 [Homo sapiens] 972 0.0
gi|12545395 islet cell autoantigen 1 [Homo sapiens] 972 0.0
gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo ... 415 e-116
gi|30102946 islet cell autoantigen 1,69kDa-like isoform 2 [Homo ... 102 1e-21
gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo s... 41 0.002
gi|71040094 ADP-ribosylation factor interacting protein 1 isofor... 41 0.002
gi|71040092 ADP-ribosylation factor interacting protein 1 isofor... 41 0.002
gi|7657210 ADP-ribosylation factor interacting protein 1 isoform... 41 0.002
gi|96975038 coiled-coil domain containing 100 [Homo sapiens] 40 0.006
gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo s... 39 0.011
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 39 0.014
gi|4504063 golgin 97 [Homo sapiens] 39 0.014
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 38 0.018
gi|24415404 MDN1, midasin homolog [Homo sapiens] 38 0.018
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 35 0.12
gi|94721344 zinc finger, CW type with PWWP domain 1 [Homo sapiens] 35 0.12
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 35 0.15
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 35 0.15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 35 0.20
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens] 34 0.34
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 33 0.44
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 33 0.44
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 33 0.58
gi|117938307 doublecortin domain containing 2 [Homo sapiens] 33 0.75
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 33 0.75
gi|4758220 XAP-5 protein [Homo sapiens] 32 0.99
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 32 0.99
gi|145580615 KRI1 homolog [Homo sapiens] 32 0.99
gi|207113199 erythrocyte membrane protein band 4.1-like 2 isofor... 32 0.99
>gi|209862841 islet cell autoantigen 1 [Homo sapiens]
Length = 483
Score = 972 bits (2512), Expect = 0.0
Identities = 483/483 (100%), Positives = 483/483 (100%)
Query: 1 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL 60
MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
Sbjct: 1 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL 60
Query: 61 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL 120
ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
Sbjct: 61 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL 120
Query: 121 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL 180
CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
Sbjct: 121 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL 180
Query: 181 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH 240
DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
Sbjct: 181 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH 240
Query: 241 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS 300
FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
Sbjct: 241 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS 300
Query: 301 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA 360
QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
Sbjct: 301 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA 360
Query: 361 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ 420
GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
Sbjct: 361 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ 420
Query: 421 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL 480
TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
Sbjct: 421 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL 480
Query: 481 LNA 483
LNA
Sbjct: 481 LNA 483
>gi|94721350 islet cell autoantigen 1 [Homo sapiens]
Length = 483
Score = 972 bits (2512), Expect = 0.0
Identities = 483/483 (100%), Positives = 483/483 (100%)
Query: 1 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL 60
MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
Sbjct: 1 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL 60
Query: 61 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL 120
ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
Sbjct: 61 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL 120
Query: 121 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL 180
CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
Sbjct: 121 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL 180
Query: 181 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH 240
DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
Sbjct: 181 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH 240
Query: 241 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS 300
FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
Sbjct: 241 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS 300
Query: 301 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA 360
QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
Sbjct: 301 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA 360
Query: 361 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ 420
GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
Sbjct: 361 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ 420
Query: 421 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL 480
TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
Sbjct: 421 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL 480
Query: 481 LNA 483
LNA
Sbjct: 481 LNA 483
>gi|12545395 islet cell autoantigen 1 [Homo sapiens]
Length = 483
Score = 972 bits (2512), Expect = 0.0
Identities = 483/483 (100%), Positives = 483/483 (100%)
Query: 1 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL 60
MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
Sbjct: 1 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL 60
Query: 61 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL 120
ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
Sbjct: 61 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL 120
Query: 121 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL 180
CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
Sbjct: 121 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL 180
Query: 181 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH 240
DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
Sbjct: 181 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH 240
Query: 241 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS 300
FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
Sbjct: 241 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS 300
Query: 301 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA 360
QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
Sbjct: 301 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA 360
Query: 361 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ 420
GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
Sbjct: 361 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ 420
Query: 421 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL 480
TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
Sbjct: 421 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL 480
Query: 481 LNA 483
LNA
Sbjct: 481 LNA 483
>gi|22095388 islet cell autoantigen 1,69kDa-like isoform 1 [Homo
sapiens]
Length = 482
Score = 415 bits (1066), Expect = e-116
Identities = 243/500 (48%), Positives = 305/500 (61%), Gaps = 52/500 (10%)
Query: 13 QDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLD 72
Q R ++SVV +MQ+KYW+TKQ FIKATGKKEDEH+VASDA+LDAKLE+FHS+Q TC +
Sbjct: 6 QPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTE 65
Query: 73 LSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRN 132
L K I YQ R+ +S+EENELG FL+ Q +D T+AGKMM ATGKALC S++QRLAL
Sbjct: 66 LLKIIEKYQLRLNVISEEENELGLFLKFQAERDATQAGKMMDATGKALCSSAKQRLALCT 125
Query: 133 PLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFR 192
PL R QEV TF RA+SDT +T+NRMEQ RTEYRGALLWMKDVSQELDPD KQMEKFR
Sbjct: 126 PLSRLKQEVATFSQRAVSDTLMTINRMEQARTEYRGALLWMKDVSQELDPDTLKQMEKFR 185
Query: 193 KVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAI 252
KVQ QVR +K +FDKLKMDVCQKVDLLGASRCN+LSH L TYQ TLL FW+KT+ M+ I
Sbjct: 186 KVQMQVRNSKASFDKLKMDVCQKVDLLGASRCNMLSHSLTTYQRTLLGFWKKTARMMSQI 245
Query: 253 HESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRK 312
HE+ G+ PY+F LK LQD K+ E N+ E + E + L +E
Sbjct: 246 HEACIGFHPYDFVALKQLQDTPSKISED------NKDEQIGGFLTEQLNKLVLSDEEASF 299
Query: 313 ESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDD 372
ES + + + G+ + S + + L + S EG E +K +
Sbjct: 300 ESEQANKDHNEKHSQMREFGAPQFSNSENVAKDLPVDSLEG------------EDFEK-E 346
Query: 373 LLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLD 432
L+ + ++ S EF++E FG ++G +P A + S FLPSQL D
Sbjct: 347 FSFLNNLLSSGSSSTSEFTQECQTAFGSPSASLTSQEPSMGS-EPLAHS-SRFLPSQLFD 404
Query: 433 --------------QNMKDLQAS---------------LQEPAKAASDLTAWFSLFADLD 463
Q +L S + P D++AWF+LFADLD
Sbjct: 405 LGFHVAGAFNNWVSQEESELCLSHTDNQPVPSQSPKKLTRSPNNGNQDMSAWFNLFADLD 464
Query: 464 PLSNPDAVGKTDKEHELLNA 483
PLSNPDA+G +D ELLNA
Sbjct: 465 PLSNPDAIGHSD--DELLNA 482
>gi|30102946 islet cell autoantigen 1,69kDa-like isoform 2 [Homo
sapiens]
Length = 82
Score = 102 bits (253), Expect = 1e-21
Identities = 48/72 (66%), Positives = 59/72 (81%)
Query: 13 QDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLD 72
Q R ++SVV +MQ+KYW+TKQ FIKATGKKEDEH+VASDA+LDAKLE+FHS+Q TC +
Sbjct: 6 QPRPEDNQSVVRRMQKKYWKTKQVFIKATGKKEDEHLVASDAELDAKLEVFHSVQETCTE 65
Query: 73 LSKAIVLYQKRI 84
L K I YQ R+
Sbjct: 66 LLKIIEKYQLRL 77
>gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo
sapiens]
Length = 1638
Score = 41.2 bits (95), Expect = 0.002
Identities = 74/318 (23%), Positives = 133/318 (41%), Gaps = 78/318 (24%)
Query: 60 LELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKA 119
L+L ++QRT LD + A Y++RI L QE+ EL + L Q+ T+ + +Q +
Sbjct: 425 LDLDVNVQRT-LDNNLATEAYERRIKRLEQEKLELSRKL-----QESTQTVQALQYSTVD 478
Query: 120 LCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQE 179
++ + L ++N +E+E R + + L ++E+ V QE
Sbjct: 479 GPLTASKDLEIKN----LKEEIEKLRKQVTESSHLE-QQLEEANA-----------VRQE 522
Query: 180 LDPDLYKQMEKFRKVQTQVR-LAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTL 238
LD D ++Q++ + K Q++ L ++ D K++V + AS+ L
Sbjct: 523 LD-DAFRQIKAYEK---QIKTLQQEREDLNKLEVHTEALAAEASKDRKLREQSE------ 572
Query: 239 LHFWEKTSHTMAAIHESFKGYQP--------YEFTTLKSLQDPMKKLVEKEE-------- 282
H+ ++ + + + + Y P E T LK+ D KK + EE
Sbjct: 573 -HYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKT--DLEKKSIFYEEELSKREGI 629
Query: 283 --------KKKINQQESTDAAVQEPSQLISLEEENQRKES--------SSFK-------- 318
KK+++ E A+ + ++ + E R+ES S FK
Sbjct: 630 HANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKV 689
Query: 319 --TEDGKSILSALDKGST 334
TE+ K + S LDK +T
Sbjct: 690 LLTEENKKLTSELDKLTT 707
>gi|71040094 ADP-ribosylation factor interacting protein 1 isoform 1
[Homo sapiens]
Length = 373
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 137 FHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQT 196
F V T ++ I DT +TV + E R EY +++++ L P + K + Q
Sbjct: 238 FIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDANTLPKIEQSQH 295
Query: 197 QVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFW----EKTSHTMAAI 252
+ K+ +DK++ DV K+ L ++ +L + L + + ++ ++ T+
Sbjct: 296 LFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQF 355
Query: 253 HESFK 257
H K
Sbjct: 356 HIKLK 360
>gi|71040092 ADP-ribosylation factor interacting protein 1 isoform 2
[Homo sapiens]
Length = 341
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 137 FHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQT 196
F V T ++ I DT +TV + E R EY +++++ L P + K + Q
Sbjct: 206 FIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDANTLPKIEQSQH 263
Query: 197 QVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFW----EKTSHTMAAI 252
+ K+ +DK++ DV K+ L ++ +L + L + + ++ ++ T+
Sbjct: 264 LFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQF 323
Query: 253 HESFK 257
H K
Sbjct: 324 HIKLK 328
>gi|7657210 ADP-ribosylation factor interacting protein 1 isoform 2
[Homo sapiens]
Length = 341
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Query: 137 FHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQT 196
F V T ++ I DT +TV + E R EY +++++ L P + K + Q
Sbjct: 206 FIASVNTLVNKTIEDTLMTVKQYESARIEYDAYRTDLEELN--LGPRDANTLPKIEQSQH 263
Query: 197 QVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFW----EKTSHTMAAI 252
+ K+ +DK++ DV K+ L ++ +L + L + + ++ ++ T+
Sbjct: 264 LFQAHKEKYDKMRNDVSVKLKFLEENKVKVLHNQLVLFHNAIAAYFAGNQKQLEQTLKQF 323
Query: 253 HESFK 257
H K
Sbjct: 324 HIKLK 328
>gi|96975038 coiled-coil domain containing 100 [Homo sapiens]
Length = 986
Score = 39.7 bits (91), Expect = 0.006
Identities = 43/237 (18%), Positives = 98/237 (41%), Gaps = 18/237 (7%)
Query: 125 QQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRM-EQCRTEYRGALLWMKDVSQELDPD 183
QQ ++ + L R +E+++ R R + + ++ R E C + L +K +L+ D
Sbjct: 724 QQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIK----QLEED 779
Query: 184 LYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLS-------HMLATYQT 236
++ ++ + + ++ +K F + K K ++ S NLL+ L +
Sbjct: 780 KHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATK 839
Query: 237 TLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAV 296
+ LH+ ++ + + + Q + LK Q+ ++++ + + E D
Sbjct: 840 SKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQM-----RLRYLAAEEKDTVK 894
Query: 297 QEPSQLISLEEE-NQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEE 352
E +L+ + E N+ ++ + +D I S G + +D+ L EE
Sbjct: 895 TERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEE 951
>gi|6912602 ADP-ribosylation factor interacting protein 2 [Homo
sapiens]
Length = 341
Score = 38.9 bits (89), Expect = 0.011
Identities = 42/196 (21%), Positives = 81/196 (41%), Gaps = 23/196 (11%)
Query: 53 DADLDAKLELFHSIQR---TCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRA 109
D +L+ ++EL +R + L L +A+ + + L Q ++ LG F D ++
Sbjct: 123 DLELELQIELLRETKRKYESVLQLGRALTAH---LYSLLQTQHALG-----DAFADLSQK 174
Query: 110 GKMMQA-------TGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQC 162
+Q T K LC + + L N F + T + + DT +TV + E
Sbjct: 175 SPELQEEFGYNAETQKLLCKNGETLLGAVN---FFVSSINTLVTKTMEDTLMTVKQYEAA 231
Query: 163 RTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGAS 222
R EY ++++S L P + Q + + ++KL+ DV K+ L +
Sbjct: 232 RLEYDAYRTDLEELS--LGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEEN 289
Query: 223 RCNLLSHMLATYQTTL 238
+ ++ L + +
Sbjct: 290 KIKVMHKQLLLFHNAV 305
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 38.5 bits (88), Expect = 0.014
Identities = 47/236 (19%), Positives = 93/236 (39%), Gaps = 8/236 (3%)
Query: 98 LRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVN 157
LR Q +++ ++ +A KA +Q R + +E+E + +
Sbjct: 1347 LREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1406
Query: 158 RMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVD 217
E ++ + + E++ DL + +E+ + ++NFDK+ + QK+D
Sbjct: 1407 NTETANSKCASLEKTKQRLQGEVE-DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLD 1465
Query: 218 LLGAS--RCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMK 275
A S L+T + + +E+ + + K Q + + + K
Sbjct: 1466 ESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGK 1525
Query: 276 KLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQR-----KESSSFKTEDGKSIL 326
L E E+ KK+ +QE +D V SLE E + E S K+E + ++
Sbjct: 1526 NLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVI 1581
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 38.5 bits (88), Expect = 0.014
Identities = 94/478 (19%), Positives = 188/478 (39%), Gaps = 88/478 (18%)
Query: 13 QDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL--------ELFH 64
Q+ + + + QK E ++ + +T +++ +HV+AS ++K+ EL
Sbjct: 213 QEELMNSNQMSSDLSQKLEELQRHY--STLEEQRDHVIASKTGAESKITALEQKEQELQA 270
Query: 65 SIQRTCLDLSK----------AIVLYQKRICFLSQ--EENELGKFLRSQGFQDKTRAGKM 112
IQ+ +DL K I Q+++ L + E+N G+ + ++KT A +
Sbjct: 271 LIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQN 330
Query: 113 MQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLW 172
++ T QQ LA R+ + +ET + + T+ E+ + +G +
Sbjct: 331 LEDT-------RQQLLAARSSQAKAINTLET----RVRELEQTLQASEEQLQQSKGIVAA 379
Query: 173 MKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLA 232
+ QE L ++ VQ Q ++ F + + ++ L +R A
Sbjct: 380 QETQIQE----LAAANQESSHVQQQALALEQQFLERTQALEAQIVALERTR--------A 427
Query: 233 TYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKI------ 286
QTT + AA+ E Y+ +L++ Q +KKL E+ +++I
Sbjct: 428 ADQTTAEQGMRQLEQENAALKECRNEYE----RSLQNHQFELKKLKEEWSQREIVSVAMA 483
Query: 287 -------NQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGKSILSALDKGSTHT--- 336
Q+E + +I +E+N R+++ ++ + + L++G
Sbjct: 484 QALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQE--ILQLERGHNSALLQ 541
Query: 337 --ACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEW 394
++ L +K+EE A + A+++DLL L A +L E
Sbjct: 542 IHQLQAELEALRTLKAEEAAVV-----------AEQEDLLRLRGPLQAEALSVNESHVTS 590
Query: 395 AAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLDQNMKDLQASLQEPAKAASDL 452
A +++PV + P + G+ L L + +DL+ L E K +
Sbjct: 591 RA------MQDPVFQLPTAGRTPNGEVGAMDLTQ--LQKEKQDLEQQLLEKNKTIKQM 640
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 38.1 bits (87), Expect = 0.018
Identities = 66/310 (21%), Positives = 121/310 (39%), Gaps = 49/310 (15%)
Query: 50 VASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRA 109
V + L+ +LE +++++ D + I Y+K+I L QE +L K L + K ++
Sbjct: 503 VTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS 562
Query: 110 GKMMQATGKALCFSSQQRLALRNPLCRFH-QEVETFRH--RAISDTWLTVNRMEQCRTEY 166
++ A + + Q+ + + L H Q+ + RH + L + ++E R E
Sbjct: 563 KELKDAHCQRK-LAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQEL 621
Query: 167 RGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNL 226
R K++ + L + K RK++ Q K + + QK C++
Sbjct: 622 RRTERAKKELEVHTEA-LAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSI 680
Query: 227 LSHMLATYQTTLLH----FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEE 282
T T L F+E+ IH + +K+L
Sbjct: 681 EHQQEITKLKTDLEKKSIFYEEELSKREGIHAN----------EIKNL------------ 718
Query: 283 KKKINQQESTDAAVQEPSQLISLEEENQRKES--------SSFK----------TEDGKS 324
KK+++ E A+ + ++ + E R+ES S FK TE+ K
Sbjct: 719 KKELHDSEGQQLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKK 778
Query: 325 ILSALDKGST 334
+ S LDK +T
Sbjct: 779 LTSELDKLTT 788
Score = 33.9 bits (76), Expect = 0.34
Identities = 39/160 (24%), Positives = 77/160 (48%), Gaps = 26/160 (16%)
Query: 60 LELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKA 119
L+L ++QRT LD + A Y++RI L QE+ EL S+ Q+ T+ + +Q +
Sbjct: 425 LDLDVNVQRT-LDNNLATEAYERRIKRLEQEKLEL-----SRKLQESTQTVQALQYSTVD 478
Query: 120 LCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQE 179
++ + L ++N +E+E R + + L ++E+ V QE
Sbjct: 479 GPLTASKDLEIKN----LKEEIEKLRKQVTESSHLE-QQLEEANA-----------VRQE 522
Query: 180 LDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLL 219
LD D ++Q++ + K Q++ ++ + L ++ Q + L
Sbjct: 523 LD-DAFRQIKAYEK---QIKTLQQEREDLNKELVQASERL 558
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 38.1 bits (87), Expect = 0.018
Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 22/179 (12%)
Query: 279 EKEEKKKINQQESTDAAV-QEPSQLIS----LEEENQRKESSSFKTEDGKSILSALDKGS 333
E++E+++ N+ E T + +E S+L++ L+ N K+ S ++ K A D G
Sbjct: 4785 EEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQ 4844
Query: 334 THTACSGPIDELLDMKSEEGACLGPVAGTPEPEGAD-KDDLLLLSEIFNASSLEEGEFSK 392
+ IDE ++E G PEPE D DDL L SE N + E +
Sbjct: 4845 GEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGE 4904
Query: 393 EWAAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLDQNMKDLQASLQEPAKAASD 451
E + ++KE P A E + + +T + DQN S QEP + S+
Sbjct: 4905 EENPL----EIKEK-PEEAGHEAEERGETET--------DQNESQ---SPQEPEEGPSE 4947
Score = 29.3 bits (64), Expect = 8.3
Identities = 68/343 (19%), Positives = 126/343 (36%), Gaps = 48/343 (13%)
Query: 57 DAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQAT 116
D+++ L S++ ++SKA+ + L +++ G + +GF +
Sbjct: 4454 DSQMALVESLEYVRGEISKAMADFTTWKTHLLTSDSQGGNQMLDEGFVED---------- 4503
Query: 117 GKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRG-ALLWMKD 175
FS Q +A+R LC E +A +T + +Y G L
Sbjct: 4504 -----FSEQMEIAIRAILCAIQNLEERKNEKAEENT-----DQASPQEDYAGFERLQSGH 4553
Query: 176 VSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKM---DVCQKVDLLGASRCNLLSHM-- 230
+++ L+ D + + VQ + + ++LK D L + C+LL +
Sbjct: 4554 LTKLLEDDFWADVSTLH-VQKIISAISELLERLKSYGEDGTAAKHLFFSQSCSLLVRLVP 4612
Query: 231 -LATYQTTLLHFW-------EKTSHTMAAIHESF-----KGY-QPYEFTTLKSLQDPMK- 275
L++Y +L F T+ ++ + + F KG+ P EF + + +
Sbjct: 4613 VLSSYSDLVLFFLTMSLATHRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGATEF 4672
Query: 276 ------KLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGKSILSAL 329
+ E E K ++ Q + V++ Q +++ S K ED +S
Sbjct: 4673 HDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSED 4732
Query: 330 DKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDD 372
G H +E + EG L G E ADK D
Sbjct: 4733 FDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLD 4775
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 35.4 bits (80), Expect = 0.12
Identities = 46/198 (23%), Positives = 83/198 (41%), Gaps = 35/198 (17%)
Query: 154 LTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLA-KKNFDKLKMDV 212
+ + +++Q EY+ L+++ Q L+ + K M+ + V L KK+ +K ++
Sbjct: 535 MEIKQLQQELQEYQNKLIYLVPEKQLLNERI-KNMQFSNTPDSGVSLLHKKSLEK--EEL 591
Query: 213 CQKV----DLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFK---------GY 259
CQ++ D L + LS M ++ L E + A+ + +K
Sbjct: 592 CQRLKEQLDALEKETASKLSEM-DSFNNQLKELRETYNTQQLALEQLYKIKRDKLKEIER 650
Query: 260 QPYEFTTLKSLQDPMKKLV--------------EKEEKKKINQQESTDAAVQEPSQLISL 305
+ E K L+D + E+EEK+K Q+E T +QE +
Sbjct: 651 KRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEER---K 707
Query: 306 EEENQRKESSSFKTEDGK 323
EE QRK+ + K E+ K
Sbjct: 708 AEEKQRKDKDTLKAEEKK 725
>gi|94721344 zinc finger, CW type with PWWP domain 1 [Homo sapiens]
Length = 648
Score = 35.4 bits (80), Expect = 0.12
Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 17/149 (11%)
Query: 273 PMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGKSILSALDKG 332
P L +KEEK + S + + +Q+ E+ ++++SS E + + L K
Sbjct: 56 PKASLKKKEEKATMKNVPSREQEKKRKAQINKQAEKKEKEKSSLTNAEFEEIVQIVLQKS 115
Query: 333 STHTACSGPIDELLDMKS----EEGACLGPVAGTPEPEGADKDDLLLLSEIFNASSLEEG 388
+ E L M S E +C PV T +DK+ + S ++ E
Sbjct: 116 ---------LQECLGMGSGLDFAETSCAQPVVSTQ----SDKEPGITASATDTDNANGEE 162
Query: 389 EFSKEWAAVFGDGQVKEPVPTMALGEPDP 417
+ +V +G+ + T LG+PDP
Sbjct: 163 VPHTQEISVSWEGEAAPEIRTSKLGQPDP 191
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 35.0 bits (79), Expect = 0.15
Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 20/162 (12%)
Query: 163 RTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLK--MDVCQKVDLLG 220
RTE GA ++++E++ + +F ++Q L K N K+K +D+ Q +
Sbjct: 175 RTEISGA-----EIAEEMEKE-----RRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYF 224
Query: 221 ASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEK 280
++CN L ++ + + T++ + K Q E L L+D +K ++
Sbjct: 225 HAQCNFFQDGLKAVESL-----KPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQV 279
Query: 281 EEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDG 322
E+K+ ++ST ++ +P +E + S +K DG
Sbjct: 280 EQKEDSQIRQSTAYSLHQPQ---GNKEHGTERNGSLYKKSDG 318
>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform a [Homo sapiens]
Length = 1006
Score = 35.0 bits (79), Expect = 0.15
Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 20/162 (12%)
Query: 163 RTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLK--MDVCQKVDLLG 220
RTE GA ++++E++ + +F ++Q L K N K+K +D+ Q +
Sbjct: 175 RTEISGA-----EIAEEMEKE-----RRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYF 224
Query: 221 ASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEK 280
++CN L ++ + + T++ + K Q E L L+D +K ++
Sbjct: 225 HAQCNFFQDGLKAVESL-----KPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQV 279
Query: 281 EEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDG 322
E+K+ ++ST ++ +P +E + S +K DG
Sbjct: 280 EQKEDSQIRQSTAYSLHQPQ---GNKEHGTERNGSLYKKSDG 318
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 34.7 bits (78), Expect = 0.20
Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 22/159 (13%)
Query: 261 PYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTE 320
P T +K + K+VEK EK+ + +E T+ + ++ ++ EEE + KE E
Sbjct: 430 PSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEET--QVTEEVTEEEEKEAKE------E 481
Query: 321 DGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDDLLLLSEIF 380
+GK ++G G +E +EE A A +P E A
Sbjct: 482 EGKE-----EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP--------A 528
Query: 381 NASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKA 419
A S E+ E +K A V + K P A P+ K+
Sbjct: 529 EAKSPEKEE-AKSPAEVKSPEKAKSPAKEEAKSPPEAKS 566
>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
Length = 440
Score = 33.9 bits (76), Expect = 0.34
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 10/101 (9%)
Query: 245 TSHTMAAIH----ESFKGYQPYEFTTLKSLQDPMKKLVEK--EEKKKINQQESTDAAVQE 298
T HT + E K Y E +++ Q+ MK L EK EE+ K++ T +V
Sbjct: 53 TPHTQCRLKLLKLERIKDYLLMEEEFIRN-QEQMKPLEEKQEEERSKVDDLRGTPMSVGT 111
Query: 299 PSQLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACS 339
++I ++N S+S +E SILS +DK CS
Sbjct: 112 LEEII---DDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCS 149
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 33.5 bits (75), Expect = 0.44
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 3/45 (6%)
Query: 279 EKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGK 323
E+EEK+K Q+E T +QE + EE QRK+ + K E+ K
Sbjct: 711 EEEEKQKRLQEEKTQEKIQEEER---KAEEKQRKDKDTLKAEEKK 752
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 33.5 bits (75), Expect = 0.44
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 3/45 (6%)
Query: 279 EKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGK 323
E+EEK+K Q+E T +QE + EE QRK+ + K E+ K
Sbjct: 711 EEEEKQKRLQEEKTQEKIQEEER---KAEEKQRKDKDTLKAEEKK 752
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 267 LKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGKSIL 326
+K + P+ +EK+++K+ ++ AVQ+ Q L+EE +R+ K +G +
Sbjct: 315 VKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEGMCSV 374
Query: 327 SALDKGSTHTACSGPIDELLDMKSEE 352
+ +G+ + S P+D K E
Sbjct: 375 RVVWRGAC-LSTSRPVDRAKRRKLRE 399
>gi|117938307 doublecortin domain containing 2 [Homo sapiens]
Length = 476
Score = 32.7 bits (73), Expect = 0.75
Identities = 30/139 (21%), Positives = 56/139 (40%), Gaps = 13/139 (9%)
Query: 285 KINQQESTDAAV---QEPSQLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGP 341
++ + E T V Q P++++ EE+ ++ + + ED + L++ A P
Sbjct: 326 EVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGREATDAP 385
Query: 342 --IDELLDMKSEEGACLGPVAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFG 399
++E+LD ++ GT E G + L ++ N L + K A G
Sbjct: 386 EQVEEILDHSEQQARPARVNGGTDEENGEE------LQQVNNELQLVLDKERKSQGA--G 437
Query: 400 DGQVKEPVPTMALGEPDPK 418
GQ + V P+ K
Sbjct: 438 SGQDEADVDPQRPPRPEVK 456
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 32.7 bits (73), Expect = 0.75
Identities = 45/218 (20%), Positives = 87/218 (39%), Gaps = 22/218 (10%)
Query: 265 TTLKSLQDPMKKLVEKEEKKKINQQE----STDAAVQEPSQLISLEEENQRKESSSFKTE 320
T +K + P K+ V+KE KK+I ++E + + P + + E + + K+ + +
Sbjct: 667 TPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEK 726
Query: 321 DGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDDLLLLSEIF 380
+ K + L K + + S P+ E +++ A L P P+ E + K D + +
Sbjct: 727 EPKKEIKKLPKDAKKS--STPLSE-----AKKPAALKP--KVPKKEESVKKDSVAAGKPK 777
Query: 381 NASSL----EEGEFSKEWAAVFGDGQVKEPVPT---MALGEPDPKAQTGSGFLPSQLLDQ 433
+ +EG+ ++ AA G G V +A P + + + S +
Sbjct: 778 EKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSP--ED 835
Query: 434 NMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAV 471
KD + E D+ L D + L + V
Sbjct: 836 LTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPV 873
>gi|4758220 XAP-5 protein [Homo sapiens]
Length = 339
Score = 32.3 bits (72), Expect = 0.99
Identities = 37/151 (24%), Positives = 68/151 (45%), Gaps = 18/151 (11%)
Query: 184 LYKQMEKFRKVQTQV--RLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF 241
L K+ EK R+ Q+ R+A++N K +D ++ + + L + L+
Sbjct: 17 LMKKREKQREQMEQMKQRIAEENIMK------SNIDKKFSAHYDAVEAELKSSTVGLVTL 70
Query: 242 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQ--------ESTD 293
+ + A + E K E + K LQ ++KL EKE KK+ ++ E +
Sbjct: 71 NDMKAKQEALVKEREKQLAKKEQS--KELQMKLEKLREKERKKEAKRKISSLSFTLEEEE 128
Query: 294 AAVQEPSQLISLEEENQRKESSSFKTEDGKS 324
+E + EEE +R+E ++ K + GK+
Sbjct: 129 EGGEEEEEAAMYEEEMEREEITTKKRKLGKN 159
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 32.3 bits (72), Expect = 0.99
Identities = 51/256 (19%), Positives = 103/256 (40%), Gaps = 35/256 (13%)
Query: 125 QQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDL 184
++RL + R H+E + + + + E+ E L ++ +E + L
Sbjct: 240 EERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERL 299
Query: 185 YKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEK 244
+Q E+ R+ + ++ ++ + + +C++ L G R LL EK
Sbjct: 300 CEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQER--------------LLEEVEK 345
Query: 245 TSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLIS 304
+ + + + + L + +++L+E+E ++ +++ +QE +L
Sbjct: 346 L------LEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRE 399
Query: 305 LEE----------ENQRKESSSFK--TEDGKSILSALDKGSTHTACSGPIDELLDMKSEE 352
LE E + + S F+ + KS L L++ SG +E SE
Sbjct: 400 LERMLELGWEALYEQRAEPRSGFEELNNENKSTLQ-LEQQVKELKKSGGAEE--PRGSES 456
Query: 353 GACLGPVAGTPEPEGA 368
A PVAG P P+GA
Sbjct: 457 AAAARPVAGAPVPQGA 472
>gi|145580615 KRI1 homolog [Homo sapiens]
Length = 709
Score = 32.3 bits (72), Expect = 0.99
Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Query: 270 LQDPMKKLVEKEEKKKINQQ----ESTDAAVQEPSQLISLEEENQRKESSSFKTEDGKSI 325
L+D +K++ ++ K ++++ E+++ +QE S +EE+ Q KES ED +
Sbjct: 121 LKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEEQKQLKESFRAFVEDSEDE 180
Query: 326 LSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADK-DDLLLLSEIFNASS 384
A + GS+ + + EE + + G E D +L L E +N
Sbjct: 181 DGAGEGGSSLLQKRAKTRQ--EKAQEEADYIEWLKGQKEIRNPDSLKELTHLKEYWNDPE 238
Query: 385 LEEGE 389
L+EGE
Sbjct: 239 LDEGE 243
>gi|207113199 erythrocyte membrane protein band 4.1-like 2 isoform b
[Homo sapiens]
Length = 673
Score = 32.3 bits (72), Expect = 0.99
Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 276 KLVEKEEKKKINQQE--STDAAVQEPSQLISLEEENQRKESSSFKTEDG 322
K+ KEEK ++++E S +P++L+S E E + KE+ K E G
Sbjct: 140 KVEVKEEKPSVSKEEKPSVSKVEMQPTELVSKEREEKVKETQEDKLEGG 188
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,407,192
Number of Sequences: 37866
Number of extensions: 845063
Number of successful extensions: 3352
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 3235
Number of HSP's gapped (non-prelim): 205
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.