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Search of human proteins with 124244083
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124244083 F-box protein 10 [Homo sapiens]
(956 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124244083 F-box protein 10 [Homo sapiens] 1950 0.0
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 168 3e-41
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 154 3e-37
gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens] 141 3e-33
gi|157743247 F-box protein 45 [Homo sapiens] 41 0.005
gi|190358504 SHC SH2-domain binding protein 1 [Homo sapiens] 40 0.014
gi|67003566 F-box protein 48 [Homo sapiens] 36 0.15
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 35 0.33
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 34 0.57
gi|208022703 modulator of retrovirus infection [Homo sapiens] 34 0.57
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 34 0.57
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H... 34 0.57
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 34 0.57
gi|93204885 chromosome 1 open reading frame 14 [Homo sapiens] 34 0.57
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 34 0.75
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 34 0.75
gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo... 33 0.97
gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo... 33 0.97
gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo s... 33 0.97
gi|71143127 IQ motif and Sec7 domain 3 [Homo sapiens] 33 1.7
gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens] 32 2.2
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 32 2.2
gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens] 32 2.2
gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens] 32 2.2
gi|14210518 PAR-6 gamma protein [Homo sapiens] 32 2.2
gi|58743365 ring finger protein 157 [Homo sapiens] 32 2.8
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 32 3.7
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 32 3.7
gi|149944548 neurobeachin-like 2 [Homo sapiens] 31 4.8
gi|29558099 protein phosphatase 1B isoform 3 [Homo sapiens] 31 4.8
>gi|124244083 F-box protein 10 [Homo sapiens]
Length = 956
Score = 1950 bits (5051), Expect = 0.0
Identities = 956/956 (100%), Positives = 956/956 (100%)
Query: 1 MEAGGLPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNW 60
MEAGGLPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNW
Sbjct: 1 MEAGGLPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNW 60
Query: 61 PNQPDVEPESWREAFKQHYLASKTWTKNALDLESSICFSLFRRRRERRTLSVGPGREFDS 120
PNQPDVEPESWREAFKQHYLASKTWTKNALDLESSICFSLFRRRRERRTLSVGPGREFDS
Sbjct: 61 PNQPDVEPESWREAFKQHYLASKTWTKNALDLESSICFSLFRRRRERRTLSVGPGREFDS 120
Query: 121 LGSALAMASLYDRIVLFPGVYEEQGEIILKVPVEIVGQGKLGEVALLASIDQHCSTTRLC 180
LGSALAMASLYDRIVLFPGVYEEQGEIILKVPVEIVGQGKLGEVALLASIDQHCSTTRLC
Sbjct: 121 LGSALAMASLYDRIVLFPGVYEEQGEIILKVPVEIVGQGKLGEVALLASIDQHCSTTRLC 180
Query: 181 NLVFTPAWFSPIMYKTTSGHVQFDNCNFENGHIQVHGPGTCQVKFCTFKNTHIFLHNVPL 240
NLVFTPAWFSPIMYKTTSGHVQFDNCNFENGHIQVHGPGTCQVKFCTFKNTHIFLHNVPL
Sbjct: 181 NLVFTPAWFSPIMYKTTSGHVQFDNCNFENGHIQVHGPGTCQVKFCTFKNTHIFLHNVPL 240
Query: 241 CVLENCEFVGSENNSVTVEGHPSADKNWAYKYLLGLIKSSPTFLPTEDSDFLMSLDLESR 300
CVLENCEFVGSENNSVTVEGHPSADKNWAYKYLLGLIKSSPTFLPTEDSDFLMSLDLESR
Sbjct: 241 CVLENCEFVGSENNSVTVEGHPSADKNWAYKYLLGLIKSSPTFLPTEDSDFLMSLDLESR 300
Query: 301 DQAWSPKTCDIVIEGSQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSP 360
DQAWSPKTCDIVIEGSQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSP
Sbjct: 301 DQAWSPKTCDIVIEGSQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSP 360
Query: 361 SGEDEDEDQLMYRLSYQVQGPRPVLGGSFLGPPLPGASIQLPSCLVLNSLQQELQKDKEA 420
SGEDEDEDQLMYRLSYQVQGPRPVLGGSFLGPPLPGASIQLPSCLVLNSLQQELQKDKEA
Sbjct: 361 SGEDEDEDQLMYRLSYQVQGPRPVLGGSFLGPPLPGASIQLPSCLVLNSLQQELQKDKEA 420
Query: 421 MALANSVQGCLIRKCLFRDGKGGVFVCSHGRAKMEGNIFRNLTYAVRCIHNSKIIMLRND 480
MALANSVQGCLIRKCLFRDGKGGVFVCSHGRAKMEGNIFRNLTYAVRCIHNSKIIMLRND
Sbjct: 421 MALANSVQGCLIRKCLFRDGKGGVFVCSHGRAKMEGNIFRNLTYAVRCIHNSKIIMLRND 480
Query: 481 IYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGN 540
IYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGN
Sbjct: 481 IYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGN 540
Query: 541 GKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQ 600
GKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQ
Sbjct: 541 GKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQ 600
Query: 601 WGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHV 660
WGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHV
Sbjct: 601 WGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHV 660
Query: 661 TSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPIT 720
TSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPIT
Sbjct: 661 TSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPIT 720
Query: 721 IALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNR 780
IALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNR
Sbjct: 721 IALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNR 780
Query: 781 QSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDIIGNRGSGLQLLPRSDTKVI 840
QSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDIIGNRGSGLQLLPRSDTKVI
Sbjct: 781 QSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDIIGNRGSGLQLLPRSDTKVI 840
Query: 841 KNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKS 900
KNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKS
Sbjct: 841 KNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKS 900
Query: 901 DTWRLVNPPARPHLENSLRRPSAAHNGQKVTAMATRITARVEGGYHSNRSVFCTIL 956
DTWRLVNPPARPHLENSLRRPSAAHNGQKVTAMATRITARVEGGYHSNRSVFCTIL
Sbjct: 901 DTWRLVNPPARPHLENSLRRPSAAHNGQKVTAMATRITARVEGGYHSNRSVFCTIL 956
>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
Length = 843
Score = 168 bits (425), Expect = 3e-41
Identities = 122/438 (27%), Positives = 196/438 (44%), Gaps = 40/438 (9%)
Query: 432 IRKCLFRDGKG-GVFVCSHGRAKMEGNIFRNLTYAVRCIHN-SKIIMLRNDIYRCRASGI 489
I+ C D + G+++ H + E N N A + N I+ RN I+ R G+
Sbjct: 316 IKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGV 375
Query: 490 FLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIRNNQ 549
F G G NI+ N AG +++ +NP ++ +IHHG GI V G+G N+
Sbjct: 376 FTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENK 435
Query: 550 IFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRG 609
I++N AG++I + +P + GN IF G G+ + +G+GLI N I N G+ IR
Sbjct: 436 IYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTN 495
Query: 610 GIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSYNG 669
P++R N I G G+ V ++G+G+IE N +Y+N GVW+ + S P + N +
Sbjct: 496 SCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGK 555
Query: 670 LYGVAVFSQKDGSSE------------------LPRGHRAQENFSEDGDAILWETELEKE 711
GV + G E P+ R + ++G +++ + L
Sbjct: 556 QVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGL--- 612
Query: 712 DDPLRRPITIALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRV 771
+E N I N +G+++++ + N IH D GI + + +
Sbjct: 613 ----------GCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGL-L 661
Query: 772 ANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIE-NDIIGNRGSGLQ 830
N I N Q+GV + LR N I+D GI +T +E N I NR GL
Sbjct: 662 EENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLF 721
Query: 831 L-----LPRSDTKVIKNR 843
L + D K++ N+
Sbjct: 722 LASGVNVTMKDNKIMNNQ 739
Score = 160 bits (404), Expect = 7e-39
Identities = 110/349 (31%), Positives = 172/349 (49%), Gaps = 17/349 (4%)
Query: 419 EAMALANSVQGCLIRKCLFRDGK-GGVFVCSHGRAK-MEGNIFRNLTYAVRCIHNSKIIM 476
E A AN + +C G+ GG++V GR + +E I+ N V NS +
Sbjct: 399 EVKAYANPT----VVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTI 454
Query: 477 LRNDIYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIV 536
N I+ G+++ +G GLI GN+IY NA AG+ IR S P++ N+IH G GI
Sbjct: 455 RGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIY 514
Query: 537 VLGNGKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVI 596
V G+G+I N+++SN AG+++ PV+ N I G+ G+ +NG G++ +N I
Sbjct: 515 VHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDI 574
Query: 597 RENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSS 656
+ + GV IR G P +R N I G + G++V + G G IE N I+ N GVW+ + S
Sbjct: 575 YNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDS 634
Query: 657 LPHVTSNHVSYNGLYGVAVFSQKDG---SSELPRGHRAQENFSEDGDAILWETELEKEDD 713
P + N + G+ +F+ G +++ R +A S + IL + + D
Sbjct: 635 NPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRI---FD 691
Query: 714 PLRRPITI-----ALVESNSINHNGASGLYVQSSEALHVITNVIHANGD 757
I I A +E N I +N GL++ S + + N I N D
Sbjct: 692 GFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQD 740
Score = 154 bits (388), Expect = 5e-37
Identities = 117/400 (29%), Positives = 187/400 (46%), Gaps = 26/400 (6%)
Query: 431 LIRKCLFRDGKG-GVFVCSHGRAKMEG-NIFRNLT--YAVRCIHNSKIIMLRNDIYRCRA 486
+IR+ G+ GVF HG E NI RN + V+ N ++ R +I+ +
Sbjct: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVV--RCEIHHGQT 418
Query: 487 SGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIR 546
GI++ +G G N IY N AGV I S+P I N I +G + G+ + G+G+G+I
Sbjct: 419 GGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIE 478
Query: 547 NNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDI 606
N I+ N AGI I + P+V N I G+ GI V+E G+G+I EN + N GV +
Sbjct: 479 GNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWV 538
Query: 607 RRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVS 666
G PVLR N I G GV D G G++E N IY + GV + + S P + N +
Sbjct: 539 TTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIW 598
Query: 667 YNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVES 726
G+ V++ G E ++ A +W ++ + +P R
Sbjct: 599 GGQNGGILVYNSGLGCIE-------DNEIFDNAMAGVW---IKTDSNPTLR--------R 640
Query: 727 NSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKV 786
N I+ G+ + + + N I N G+ ++ +S P + N I +G+++
Sbjct: 641 NKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPI-LRKNRIFDGFAAGIEI 699
Query: 787 EAQCKVELRGNGIYDNRGHGI-ITKGDSTIVIENDIIGNR 825
L GN I++NR G+ + G + + +N I+ N+
Sbjct: 700 TNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQ 739
Score = 91.3 bits (225), Expect = 4e-18
Identities = 90/374 (24%), Positives = 149/374 (39%), Gaps = 30/374 (8%)
Query: 528 HHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYILYHGN---PVVSGNHIFKGRAAGIAVN 584
HH + + N II + I S G + G P + +I G+ +
Sbjct: 273 HHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYIT 332
Query: 585 ENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYA 644
++ +G+ +N I N G+ ++ G P++R N I G GV D G G E I+
Sbjct: 333 DHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHR 392
Query: 645 NKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILW 704
N+ G + + + P V + + G+ V E RG + + A +W
Sbjct: 393 NRIAGFEVKAYANPTVVRCEIHHGQTGGIYV-------HEKGRGQFIENKIYANNFAGVW 445
Query: 705 ETELEKEDDPLRRPITI---------------ALVESNSINHNGASGLYVQSSEALHVIT 749
T DP R +I L+E N I N +G+ ++++ V
Sbjct: 446 IT---SNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRH 502
Query: 750 NVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIIT 809
N IH GI V + Q + N + N +GV V LR N I+ + G+
Sbjct: 503 NKIHDGQHGGIYVHEKGQGV-IEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYF 561
Query: 810 KGDSTIVIE-NDIIGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIF 868
+ V+E NDI + SG+Q+ S+ K+ +N+I + GI V +++N IF
Sbjct: 562 YDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIF 621
Query: 869 QGKTSKTIFQQISN 882
+ + SN
Sbjct: 622 DNAMAGVWIKTDSN 635
Score = 72.0 bits (175), Expect = 2e-12
Identities = 45/139 (32%), Positives = 71/139 (51%), Gaps = 1/139 (0%)
Query: 442 GGVFVCSHGRAKMEGN-IFRNLTYAVRCIHNSKIIMLRNDIYRCRASGIFLRLEGGGLIA 500
GG+ V + G +E N IF N V +S + RN I+ R GI + G GL+
Sbjct: 603 GGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLE 662
Query: 501 GNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYI 560
N+I+ NA+AGV I S+P++ N+I G +GI + + + NQIF+N+ G+++
Sbjct: 663 ENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFL 722
Query: 561 LYHGNPVVSGNHIFKGRAA 579
N + N I + A
Sbjct: 723 ASGVNVTMKDNKIMNNQDA 741
Score = 35.0 bits (79), Expect = 0.33
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 12/84 (14%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNWPNQP- 64
LP E+ I +YL DL R + VC+ + E L+ D W++L + E P +P
Sbjct: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSE--LANDPILWKRLYMEVFEYTRPMMHPEPG 132
Query: 65 ---DVEPES------WREAFKQHY 79
+ PE W+E+F+Q Y
Sbjct: 133 KFYQINPEEYEHPNPWKESFQQLY 156
>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
Length = 686
Score = 154 bits (390), Expect = 3e-37
Identities = 89/261 (34%), Positives = 138/261 (52%), Gaps = 6/261 (2%)
Query: 419 EAMALANSVQGCLIRKCLFRDGK-GGVFVCSHGRAK-MEGNIFRNLTYAVRCIHNSKIIM 476
E A AN + +C G+ GG++V GR + +E I+ N V NS +
Sbjct: 399 EVKAYANPT----VVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTI 454
Query: 477 LRNDIYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIV 536
N I+ G+++ +G GLI GN+IY NA AG+ IR S P++ N+IH G GI
Sbjct: 455 RGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIY 514
Query: 537 VLGNGKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVI 596
V G+G+I N+++SN AG+++ PV+ N I G+ G+ +NG G++ +N I
Sbjct: 515 VHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDI 574
Query: 597 RENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSS 656
+ + GV IR G P +R N I G + G++V + G G IE N I+ N GVW+ + S
Sbjct: 575 YNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDS 634
Query: 657 LPHVTSNHVSYNGLYGVAVFS 677
P + N + G+ +F+
Sbjct: 635 NPTLRRNKIHDGRDGGICIFN 655
Score = 153 bits (387), Expect = 6e-37
Identities = 112/396 (28%), Positives = 177/396 (44%), Gaps = 45/396 (11%)
Query: 432 IRKCLFRDGKG-GVFVCSHGRAKMEGNIFRNLTYAVRCIHN-SKIIMLRNDIYRCRASGI 489
I+ C D + G+++ H + E N N A + N I+ RN I+ R G+
Sbjct: 316 IKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGV 375
Query: 490 FLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIRNNQ 549
F G G NI+ N AG +++ +NP ++ +IHHG GI V G+G N+
Sbjct: 376 FTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENK 435
Query: 550 IFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRG 609
I++N AG++I + +P + GN IF G G+ + +G+GLI N I N G+ IR
Sbjct: 436 IYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTN 495
Query: 610 GIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSYNG 669
P++R N I G G+ V ++G+G+IE N +Y+N GVW+ + S P + N +
Sbjct: 496 SCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGK 555
Query: 670 LYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNSI 729
GV F ++G +L E N I
Sbjct: 556 QVGV--------------------YFYDNGHGVL---------------------EDNDI 574
Query: 730 NHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQ 789
++ SG+ +++ + N I + GI V S + +N I N +GV ++
Sbjct: 575 YNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGC-IEDNEIFDNAMAGVWIKTD 633
Query: 790 CKVELRGNGIYDNRGHGI-ITKGDSTIVIENDIIGN 824
LR N I+D R GI I G IV+ ++ N
Sbjct: 634 SNPTLRRNKIHDGRDGGICIFNGGRGIVVNFALVKN 669
Score = 142 bits (357), Expect = 2e-33
Identities = 105/409 (25%), Positives = 173/409 (42%), Gaps = 48/409 (11%)
Query: 480 DIYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLG 539
+I C G+++ G+ N I +NA AG+ ++ NP+I N IHHG G+
Sbjct: 320 NISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFD 379
Query: 540 NGKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIREN 599
+G G + I N+ AG + + NP V I G+ GI V+E G+G EN I N
Sbjct: 380 HGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYAN 439
Query: 600 QWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPH 659
+ GV I P +R N I G GV + +G+GLIEGN IY N G+ + ++S P
Sbjct: 440 NFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPI 499
Query: 660 VTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPI 719
V N + G+ V + G
Sbjct: 500 VRHNKIHDGQHGGIYVHEKGQG-------------------------------------- 521
Query: 720 TIALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCN 779
++E N + N +G++V + + N IH+ G+ + + +N I +
Sbjct: 522 ---VIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGV-LEDNDIYNH 577
Query: 780 RQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIE-NDIIGNRGSGLQLLPRSDTK 838
SGV++ ++R N I+ + GI+ IE N+I N +G+ + S+
Sbjct: 578 MYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPT 637
Query: 839 VIKNRIHSFRAYGIAVRGRAKALV-----QENIIFQGKTSKTIFQQISN 882
+ +N+IH R GI + + +V +N +F + + I+N
Sbjct: 638 LRRNKIHDGRDGGICIFNGGRGIVVNFALVKNPVFHYSSISLMINDIAN 686
Score = 135 bits (341), Expect = 1e-31
Identities = 90/258 (34%), Positives = 130/258 (50%), Gaps = 6/258 (2%)
Query: 431 LIRKCLFRDGKG-GVFVCSHGRAKMEG-NIFRNLT--YAVRCIHNSKIIMLRNDIYRCRA 486
+IR+ G+ GVF HG E NI RN + V+ N ++ R +I+ +
Sbjct: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVV--RCEIHHGQT 418
Query: 487 SGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIR 546
GI++ +G G N IY N AGV I S+P I N I +G + G+ + G+G+G+I
Sbjct: 419 GGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIE 478
Query: 547 NNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDI 606
N I+ N AGI I + P+V N I G+ GI V+E G+G+I EN + N GV +
Sbjct: 479 GNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWV 538
Query: 607 RRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVS 666
G PVLR N I G GV D G G++E N IY + GV + + S P + N +
Sbjct: 539 TTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIW 598
Query: 667 YNGLYGVAVFSQKDGSSE 684
G+ V++ G E
Sbjct: 599 GGQNGGILVYNSGLGCIE 616
Score = 91.3 bits (225), Expect = 4e-18
Identities = 90/374 (24%), Positives = 149/374 (39%), Gaps = 30/374 (8%)
Query: 528 HHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYILYHGN---PVVSGNHIFKGRAAGIAVN 584
HH + + N II + I S G + G P + +I G+ +
Sbjct: 273 HHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYIT 332
Query: 585 ENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYA 644
++ +G+ +N I N G+ ++ G P++R N I G GV D G G E I+
Sbjct: 333 DHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHR 392
Query: 645 NKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILW 704
N+ G + + + P V + + G+ V E RG + + A +W
Sbjct: 393 NRIAGFEVKAYANPTVVRCEIHHGQTGGIYV-------HEKGRGQFIENKIYANNFAGVW 445
Query: 705 ETELEKEDDPLRRPITI---------------ALVESNSINHNGASGLYVQSSEALHVIT 749
T DP R +I L+E N I N +G+ ++++ V
Sbjct: 446 IT---SNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRH 502
Query: 750 NVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIIT 809
N IH GI V + Q + N + N +GV V LR N I+ + G+
Sbjct: 503 NKIHDGQHGGIYVHEKGQGV-IEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYF 561
Query: 810 KGDSTIVIE-NDIIGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIF 868
+ V+E NDI + SG+Q+ S+ K+ +N+I + GI V +++N IF
Sbjct: 562 YDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIF 621
Query: 869 QGKTSKTIFQQISN 882
+ + SN
Sbjct: 622 DNAMAGVWIKTDSN 635
Score = 35.0 bits (79), Expect = 0.33
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 12/84 (14%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNWPNQP- 64
LP E+ I +YL DL R + VC+ + E L+ D W++L + E P +P
Sbjct: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSE--LANDPILWKRLYMEVFEYTRPMMHPEPG 132
Query: 65 ---DVEPES------WREAFKQHY 79
+ PE W+E+F+Q Y
Sbjct: 133 KFYQINPEEYEHPNPWKESFQQLY 156
>gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]
Length = 585
Score = 141 bits (355), Expect = 3e-33
Identities = 82/255 (32%), Positives = 128/255 (50%), Gaps = 2/255 (0%)
Query: 432 IRKCLFRDGKG-GVFVCSHGRAKMEGNIFRNLTYAVRCIHN-SKIIMLRNDIYRCRASGI 489
I+ C D + G+++ H + E N N A + N I+ RN I+ R G+
Sbjct: 316 IKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGV 375
Query: 490 FLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIRNNQ 549
F G G NI+ N AG +++ +NP ++ +IHHG GI V G+G N+
Sbjct: 376 FTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENK 435
Query: 550 IFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRG 609
I++N AG++I + +P + GN IF G G+ + +G+GLI N I N G+ IR
Sbjct: 436 IYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTN 495
Query: 610 GIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSYNG 669
P++R N I G G+ V ++G+G+IE N +Y+N GVW+ + S P + N +
Sbjct: 496 SCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGK 555
Query: 670 LYGVAVFSQKDGSSE 684
GV + G E
Sbjct: 556 QVGVYFYDNGHGVLE 570
Score = 128 bits (322), Expect = 2e-29
Identities = 83/224 (37%), Positives = 116/224 (51%), Gaps = 6/224 (2%)
Query: 431 LIRKCLFRDGKG-GVFVCSHGRAKMEG-NIFRNLT--YAVRCIHNSKIIMLRNDIYRCRA 486
+IR+ G+ GVF HG E NI RN + V+ N ++ R +I+ +
Sbjct: 361 IIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVV--RCEIHHGQT 418
Query: 487 SGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIR 546
GI++ +G G N IY N AGV I S+P I N I +G + G+ + G+G+G+I
Sbjct: 419 GGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIE 478
Query: 547 NNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDI 606
N I+ N AGI I + P+V N I G+ GI V+E G+G+I EN + N GV +
Sbjct: 479 GNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWV 538
Query: 607 RRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGV 650
G PVLR N I G GV D G G++E N IY + GV
Sbjct: 539 TTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGV 582
Score = 115 bits (287), Expect = 3e-25
Identities = 66/191 (34%), Positives = 102/191 (53%), Gaps = 6/191 (3%)
Query: 419 EAMALANSVQGCLIRKCLFRDGK-GGVFVCSHGRAK-MEGNIFRNLTYAVRCIHNSKIIM 476
E A AN + +C G+ GG++V GR + +E I+ N V NS +
Sbjct: 399 EVKAYANPT----VVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTI 454
Query: 477 LRNDIYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIV 536
N I+ G+++ +G GLI GN+IY NA AG+ IR S P++ N+IH G GI
Sbjct: 455 RGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIY 514
Query: 537 VLGNGKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVI 596
V G+G+I N+++SN AG+++ PV+ N I G+ G+ +NG G++ +N I
Sbjct: 515 VHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDI 574
Query: 597 RENQWGGVDIR 607
+ + GV IR
Sbjct: 575 YNHMYSGVQIR 585
Score = 77.0 bits (188), Expect = 8e-14
Identities = 78/323 (24%), Positives = 127/323 (39%), Gaps = 30/323 (9%)
Query: 528 HHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYILYHGN---PVVSGNHIFKGRAAGIAVN 584
HH + + N II + I S G + G P + +I G+ +
Sbjct: 273 HHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYIT 332
Query: 585 ENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYA 644
++ +G+ +N I N G+ ++ G P++R N I G GV D G G E I+
Sbjct: 333 DHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHR 392
Query: 645 NKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILW 704
N+ G + + + P V + + G+ V E RG + + A +W
Sbjct: 393 NRIAGFEVKAYANPTVVRCEIHHGQTGGIYV-------HEKGRGQFIENKIYANNFAGVW 445
Query: 705 ETELEKEDDPLRRPITI---------------ALVESNSINHNGASGLYVQSSEALHVIT 749
T DP R +I L+E N I N +G+ ++++ V
Sbjct: 446 IT---SNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRH 502
Query: 750 NVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIIT 809
N IH GI V + Q + N + N +GV V LR N I+ + G+
Sbjct: 503 NKIHDGQHGGIYVHEKGQGV-IEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYF 561
Query: 810 KGDSTIVIE-NDIIGNRGSGLQL 831
+ V+E NDI + SG+Q+
Sbjct: 562 YDNGHGVLEDNDIYNHMYSGVQI 584
Score = 75.5 bits (184), Expect = 2e-13
Identities = 67/285 (23%), Positives = 115/285 (40%), Gaps = 43/285 (15%)
Query: 608 RGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSY 667
+G P ++ I + G+ + D +G+ E N I N G+W+ + P + NH+ +
Sbjct: 310 QGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHH 369
Query: 668 NGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESN 727
GV F G E HR + + E++ +P T+ E
Sbjct: 370 GRDVGVFTFDHGMGYFESCNIHRNR----------IAGFEVKAYANP-----TVVRCE-- 412
Query: 728 SINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVE 787
I+H G+YV I N I+AN G+ + +S PT + NSI Q GV +
Sbjct: 413 -IHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPT-IRGNSIFNGNQGGVYIF 470
Query: 788 AQCKVELRGNGIYDNRGHGIITKGDSTIVI------------------------ENDIIG 823
+ + GN IY N GI + +S ++ EN++
Sbjct: 471 GDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYS 530
Query: 824 NRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIF 868
N +G+ + S + +NRIHS + G+ ++++N I+
Sbjct: 531 NTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIY 575
Score = 35.0 bits (79), Expect = 0.33
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 12/84 (14%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNWPNQP- 64
LP E+ I +YL DL R + VC+ + E L+ D W++L + E P +P
Sbjct: 75 LPDEVVLKIFSYLLEQDLCRAACVCKRFSE--LANDPILWKRLYMEVFEYTRPMMHPEPG 132
Query: 65 ---DVEPES------WREAFKQHY 79
+ PE W+E+F+Q Y
Sbjct: 133 KFYQINPEEYEHPNPWKESFQQLY 156
>gi|157743247 F-box protein 45 [Homo sapiens]
Length = 286
Score = 41.2 bits (95), Expect = 0.005
Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 4 GGLPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTR-WRQLC 49
G LP + ++ +YL L +L C+LVC+ WY + +++ WR LC
Sbjct: 37 GRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLC 83
>gi|190358504 SHC SH2-domain binding protein 1 [Homo sapiens]
Length = 672
Score = 39.7 bits (91), Expect = 0.014
Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 440 GKGGVFV-CSHGRAKMEGNIF--RNLTYAVRCIHNSKIIMLRNDIYRCRASGIFLRLEGG 496
GKG FV C+ K+ G F + + +H K L N + +C +G+ +R
Sbjct: 418 GKGDTFVDCTGADIKISGIKFVQHDAVEGILIVHRGKTT-LENCVLQCETTGVTVRTSAE 476
Query: 497 GLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVV 537
L+ +++Y AG++I S + N IHH + GI++
Sbjct: 477 FLMKNSDLYGAKGAGIEIYPGSQCTLSDNGIHH-CKEGILI 516
>gi|67003566 F-box protein 48 [Homo sapiens]
Length = 155
Score = 36.2 bits (82), Expect = 0.15
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGC-TECRHPNWPNQP 64
LP E+ I + L + L R SL CR+W + I + DS W+ C+ CR
Sbjct: 38 LPAEITFKIFSQLDIRSLCRASLTCRSWNDTIRNSDSL-WKPHCMTVRAVCRR---EIDD 93
Query: 65 DVEP-ESWREAFKQHYLASKTWTKNALDLESSIC 97
D+E SWR ++Y SK + S+IC
Sbjct: 94 DLESGYSWRVILLRNYQKSKVKHEWLSGRYSNIC 127
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo
sapiens]
Length = 436
Score = 35.0 bits (79), Expect = 0.33
Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCL 50
LP EL I ++L + L RC+ V RAW +L+LD + W+++ L
Sbjct: 28 LPKELLLRIFSFLDVVTLCRCAQVSRAWN--VLALDGSNWQRIDL 70
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 34.3 bits (77), Expect = 0.57
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 314 EGSQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSPSGEDEDEDQ 369
EG+ S +P +S + G+K G D D+SDG S +G DEDED+
Sbjct: 207 EGNTSEITPQINSKRNGTKEAEVTPGTGEDAGL-----DNSDGSPSGNGADEDEDE 257
>gi|208022703 modulator of retrovirus infection [Homo sapiens]
Length = 157
Score = 34.3 bits (77), Expect = 0.57
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 10/89 (11%)
Query: 290 DFLMSLDLESRDQAWSPKTCDI-VIEGSQSP--TSPASSSPKPGSKAGSQEAEVG----S 342
D + + +ESR Q K C+ + G+ +P + P S SP S + S+E + G +
Sbjct: 63 DVALGILIESRKQE---KACEQPALAGADNPEHSPPCSVSPHTSSGSSSEEEDSGKQALA 119
Query: 343 DGERVAQTPDSSDGGLSPSGEDEDEDQLM 371
G +Q P S S S E+E+E+ ++
Sbjct: 120 PGLSPSQRPGGSSSACSRSPEEEEEEDVL 148
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo
sapiens]
Length = 423
Score = 34.3 bits (77), Expect = 0.57
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCL 50
LP EL I ++L + L RC+ + +AW IL+LD + W+++ L
Sbjct: 15 LPKELLLRIFSFLDIVTLCRCAQISKAWN--ILALDGSNWQRIDL 57
>gi|30795121 F-box and WD repeat domain containing 8 isoform 2
[Homo sapiens]
Length = 532
Score = 34.3 bits (77), Expect = 0.57
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLC 49
LP EL I YL +LGRC+ V + W +++ D W +LC
Sbjct: 53 LPYELAINIFQYLDRKELGRCAQVSKTW--KVIAEDEVLWYRLC 94
>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
sapiens]
Length = 598
Score = 34.3 bits (77), Expect = 0.57
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 2/44 (4%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLC 49
LP EL I YL +LGRC+ V + W +++ D W +LC
Sbjct: 119 LPYELAINIFQYLDRKELGRCAQVSKTW--KVIAEDEVLWYRLC 160
>gi|93204885 chromosome 1 open reading frame 14 [Homo sapiens]
Length = 653
Score = 34.3 bits (77), Expect = 0.57
Identities = 29/98 (29%), Positives = 44/98 (44%), Gaps = 13/98 (13%)
Query: 477 LRNDIYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHH--GLRS- 533
L N I +C +G+ + I + I AGV++ S ++ N+IHH LR+
Sbjct: 498 LENCILKCEGTGVCVLTGAALTITDSEITGAQGAGVELYPGSIAILERNEIHHCNNLRTS 557
Query: 534 ----------GIVVLGNGKGIIRNNQIFSNKEAGIYIL 561
+ VL K + NN I+SNK G+ IL
Sbjct: 558 NSSKSTLGGVNMKVLPAPKLKMTNNHIYSNKGYGVSIL 595
Score = 32.0 bits (71), Expect = 2.8
Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 18/109 (16%)
Query: 557 GIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRGGIPVLRS 616
GI ++ G+ + N I K G+ V IT++ I Q GV++ G I +L
Sbjct: 487 GIVVVESGHMTLE-NCILKCEGTGVCVLTGAALTITDSEITGAQGAGVELYPGSIAILER 545
Query: 617 NLICFGYSDGVVVGDEGKGLIEG---------------NTIYANKGCGV 650
N I + + + + K + G N IY+NKG GV
Sbjct: 546 NEI--HHCNNLRTSNSSKSTLGGVNMKVLPAPKLKMTNNHIYSNKGYGV 592
Score = 31.2 bits (69), Expect = 4.8
Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 125 LAMASLY--DRIVLFPGVYEEQGEIILKVPVEIVGQGKLGEVALLAS------IDQHCST 176
LA+ + Y D +++FPG Y+ +L + I G GK E+ + + +
Sbjct: 412 LALDNCYSGDTVIIFPGEYQAANLALLTDDIIIKGVGKREEIMITSEPSRDSFVVSKADN 471
Query: 177 TRLCNLVFTPAWFSPIMYKTTSGHVQFDNCNFENGHIQVHGPGTC 221
+L +L + SGH+ +NC ++ G G C
Sbjct: 472 VKLMHLSLIQQGTVDGIVVVESGHMTLENC-----ILKCEGTGVC 511
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 33.9 bits (76), Expect = 0.75
Identities = 29/75 (38%), Positives = 31/75 (41%), Gaps = 8/75 (10%)
Query: 347 VAQTPDSSDGGLSPSGEDEDEDQLMYRLS-----YQVQGPRPVLGGSFLGPPLPGASIQL 401
V QTP S D GL S E + Y PRP LGGS P LP S +
Sbjct: 911 VTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSI--PTLPLRSNSI 968
Query: 402 PSCL-VLNSLQQELQ 415
P VL QQ LQ
Sbjct: 969 PGARPVLQQQQQMLQ 983
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 33.9 bits (76), Expect = 0.75
Identities = 29/75 (38%), Positives = 31/75 (41%), Gaps = 8/75 (10%)
Query: 347 VAQTPDSSDGGLSPSGEDEDEDQLMYRLS-----YQVQGPRPVLGGSFLGPPLPGASIQL 401
V QTP S D GL S E + Y PRP LGGS P LP S +
Sbjct: 911 VTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSI--PTLPLRSNSI 968
Query: 402 PSCL-VLNSLQQELQ 415
P VL QQ LQ
Sbjct: 969 PGARPVLQQQQQMLQ 983
>gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo
sapiens]
Length = 1977
Score = 33.5 bits (75), Expect = 0.97
Identities = 35/131 (26%), Positives = 58/131 (44%), Gaps = 17/131 (12%)
Query: 239 PLCVLENCEFVGSENNSVTVEGHPSADKNWAYKYLLGLIKSSPTFLPTEDSDFLMSLDLE 298
P+ + N +FV +EN+S+ + +P+ D K T T D +++ +
Sbjct: 555 PMSPVLNSKFVPAENDSILM--NPAQDGEVQLSQNDDKTKGDDT--DTRDDISILATGCK 610
Query: 299 SRDQAWSPKTC-DIVIE-GSQSPTSPASSSPKPGSKAGSQEA--------EVGSDG---E 345
R++ + C D+ + GSQ+ SPA+ S S +EA E GS G E
Sbjct: 611 GREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVE 670
Query: 346 RVAQTPDSSDG 356
+ +TP S G
Sbjct: 671 EIPETPCESQG 681
>gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo
sapiens]
Length = 1975
Score = 33.5 bits (75), Expect = 0.97
Identities = 35/131 (26%), Positives = 58/131 (44%), Gaps = 17/131 (12%)
Query: 239 PLCVLENCEFVGSENNSVTVEGHPSADKNWAYKYLLGLIKSSPTFLPTEDSDFLMSLDLE 298
P+ + N +FV +EN+S+ + +P+ D K T T D +++ +
Sbjct: 555 PMSPVLNSKFVPAENDSILM--NPAQDGEVQLSQNDDKTKGDDT--DTRDDISILATGCK 610
Query: 299 SRDQAWSPKTC-DIVIE-GSQSPTSPASSSPKPGSKAGSQEA--------EVGSDG---E 345
R++ + C D+ + GSQ+ SPA+ S S +EA E GS G E
Sbjct: 611 GREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVE 670
Query: 346 RVAQTPDSSDG 356
+ +TP S G
Sbjct: 671 EIPETPCESQG 681
>gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo
sapiens]
Length = 1972
Score = 33.5 bits (75), Expect = 0.97
Identities = 35/131 (26%), Positives = 58/131 (44%), Gaps = 17/131 (12%)
Query: 239 PLCVLENCEFVGSENNSVTVEGHPSADKNWAYKYLLGLIKSSPTFLPTEDSDFLMSLDLE 298
P+ + N +FV +EN+S+ + +P+ D K T T D +++ +
Sbjct: 550 PMSPVLNSKFVPAENDSILM--NPAQDGEVQLSQNDDKTKGDDT--DTRDDISILATGCK 605
Query: 299 SRDQAWSPKTC-DIVIE-GSQSPTSPASSSPKPGSKAGSQEA--------EVGSDG---E 345
R++ + C D+ + GSQ+ SPA+ S S +EA E GS G E
Sbjct: 606 GREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVE 665
Query: 346 RVAQTPDSSDG 356
+ +TP S G
Sbjct: 666 EIPETPCESQG 676
>gi|71143127 IQ motif and Sec7 domain 3 [Homo sapiens]
Length = 759
Score = 32.7 bits (73), Expect = 1.7
Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 9/62 (14%)
Query: 317 QSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDS---------SDGGLSPSGEDEDE 367
Q+P PA+ + G +G + E + G A DS +DG +P E+E+E
Sbjct: 214 QAPAEPAAGKAEQGETSGREAPEAPAVGREDASAEDSCAEAAASGAADGATAPKTEEEEE 273
Query: 368 DQ 369
++
Sbjct: 274 EE 275
>gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]
Length = 728
Score = 32.3 bits (72), Expect = 2.2
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 18/97 (18%)
Query: 280 SPTFLPTEDSDFLMSLDLESRDQAWSPKTCDIVIEGSQSPTSPASSSPKPGSKAGSQEAE 339
+P P ED D +++ESR++ TS SS P + S +
Sbjct: 469 APVAAPEEDKDSEAEVEVESREEF----------------TSSLSSLSSPSFTSSSSAKD 512
Query: 340 VGSDGERV--AQTPDSSDGGLSPSGEDEDEDQLMYRL 374
+GS G R + PD++ +PSG + + + L L
Sbjct: 513 LGSPGARALPSAVPDAAAPADAPSGLEAELEHLRQAL 549
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 32.3 bits (72), Expect = 2.2
Identities = 17/56 (30%), Positives = 23/56 (41%)
Query: 314 EGSQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSPSGEDEDEDQ 369
+GSQ+ +P P PG+ Q G AQT GG G D+ + Q
Sbjct: 19 QGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQ 74
>gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens]
Length = 758
Score = 32.3 bits (72), Expect = 2.2
Identities = 23/56 (41%), Positives = 25/56 (44%), Gaps = 6/56 (10%)
Query: 316 SQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSPSGEDEDEDQLM 371
S P A + P P S+ G EAEV DG TP DG GE E E LM
Sbjct: 493 SLEPEDAAPTPPGPSSEGGPAEAEV--DGA----TPTEGDGDGDGEGEGEGEAVLM 542
>gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens]
Length = 758
Score = 32.3 bits (72), Expect = 2.2
Identities = 23/56 (41%), Positives = 25/56 (44%), Gaps = 6/56 (10%)
Query: 316 SQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSPSGEDEDEDQLM 371
S P A + P P S+ G EAEV DG TP DG GE E E LM
Sbjct: 493 SLEPEDAAPTPPGPSSEGGPAEAEV--DGA----TPTEGDGDGDGEGEGEGEAVLM 542
>gi|14210518 PAR-6 gamma protein [Homo sapiens]
Length = 376
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 301 DQAWSPKTCDIVIEGSQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGL 358
D+A S + D+VIEG+ P P + PG+ AGS G+ + Q + DGGL
Sbjct: 291 DEAESDEDNDVVIEGTLEPARPPQT---PGAPAGSLSRVNGAGLAQRLQRDLALDGGL 345
>gi|58743365 ring finger protein 157 [Homo sapiens]
Length = 679
Score = 32.0 bits (71), Expect = 2.8
Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 6/45 (13%)
Query: 323 ASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSPSGEDEDE 367
A SSP+P S+A S+E E A++PDS+ GL P+GE + E
Sbjct: 550 ALSSPQPASRAPSEEGE-----GLPAESPDSNFAGL-PAGEQDAE 588
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 31.6 bits (70), Expect = 3.7
Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCL 50
LP EL I + L LP+L + S VC+ WY L+ D + W+ L L
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYR--LASDESLWQTLDL 142
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 31.6 bits (70), Expect = 3.7
Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCL 50
LP EL I + L LP+L + S VC+ WY L+ D + W+ L L
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYR--LASDESLWQTLDL 142
>gi|149944548 neurobeachin-like 2 [Homo sapiens]
Length = 2754
Score = 31.2 bits (69), Expect = 4.8
Identities = 15/44 (34%), Positives = 24/44 (54%)
Query: 317 QSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSP 360
+SPTSP + PKP +++ ++ ++V E PD LSP
Sbjct: 1308 ESPTSPKPAPPKPPTESPAEPSDVFLPSEAPCPDPDGFYHALSP 1351
>gi|29558099 protein phosphatase 1B isoform 3 [Homo sapiens]
Length = 192
Score = 31.2 bits (69), Expect = 4.8
Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 4/55 (7%)
Query: 313 IEGSQSPTSPASSSPKPGSKAGS----QEAEVGSDGERVAQTPDSSDGGLSPSGE 363
+EG +SP PA+++ S AG+ QE+ S+ + D G SGE
Sbjct: 136 VEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGE 190
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,666,693
Number of Sequences: 37866
Number of extensions: 1952144
Number of successful extensions: 6417
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 6198
Number of HSP's gapped (non-prelim): 136
length of query: 956
length of database: 18,247,518
effective HSP length: 112
effective length of query: 844
effective length of database: 14,006,526
effective search space: 11821507944
effective search space used: 11821507944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.