Guide to the Human Genome
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Search of human proteins with 12408677

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12408677 prefoldin subunit 4 [Homo sapiens]
         (134 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12408677 prefoldin subunit 4 [Homo sapiens]                        259   3e-70
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       40   4e-04
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       40   4e-04
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        40   4e-04
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        40   4e-04
gi|38044112 restin isoform b [Homo sapiens]                            40   4e-04
gi|4506751 restin isoform a [Homo sapiens]                             40   4e-04
gi|5730075 fibrinogen-like 2 precursor [Homo sapiens]                  39   0.001
gi|96975038 coiled-coil domain containing 100 [Homo sapiens]           37   0.005
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    36   0.008
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       36   0.011
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi...    35   0.014
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             35   0.014
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    35   0.014
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo...    35   0.014
gi|18079254 p53 and DNA damage-regulated protein [Homo sapiens]        35   0.018
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    35   0.018
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     35   0.018
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    35   0.024
gi|15618995 keratin 71 [Homo sapiens]                                  35   0.024
gi|237858621 polyamine modulated factor 1 binding protein 1 isof...    35   0.024
gi|237858619 polyamine modulated factor 1 binding protein 1 isof...    35   0.024
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    35   0.024
gi|119395750 keratin 1 [Homo sapiens]                                  34   0.031
gi|112420968 coiled-coil domain containing 158 [Homo sapiens]          34   0.031
gi|31982906 cingulin-like 1 [Homo sapiens]                             34   0.031
gi|56961680 coiled-coil domain containing 147 [Homo sapiens]           34   0.031
gi|42794779 myosin 18A isoform b [Homo sapiens]                        34   0.040
gi|28416946 myosin 18A isoform a [Homo sapiens]                        34   0.040
gi|239754018 PREDICTED: hypothetical protein LOC100129791 [Homo ...    33   0.052

>gi|12408677 prefoldin subunit 4 [Homo sapiens]
          Length = 134

 Score =  259 bits (663), Expect = 3e-70
 Identities = 134/134 (100%), Positives = 134/134 (100%)

Query: 1   MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLA 60
           MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLA
Sbjct: 1   MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLA 60

Query: 61  DDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLY 120
           DDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLY
Sbjct: 61  DDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLY 120

Query: 121 AKFGSNINLEADES 134
           AKFGSNINLEADES
Sbjct: 121 AKFGSNINLEADES 134


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 20/88 (22%)

Query: 35  ELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNL 94
           E KE +E K++ ++ + D  D I +A  D                    +EM EE  ++L
Sbjct: 148 EAKEALEAKERYMEEMADTADAIEMATLD--------------------KEMAEERAESL 187

Query: 95  QEEIDALESRVESIQRVLADLKVQLYAK 122
           Q+E++AL+ RV+ +   L  LK ++  K
Sbjct: 188 QQEVEALKERVDELTTDLEILKAEIEEK 215



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 10/110 (9%)

Query: 10  AEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPY 69
           AE + +  ED++ + K  + + +I    EE+     +L  LE   D      D+ +    
Sbjct: 804 AEGLGLKLEDRETVIKELKKSLKIKG--EELSEANVRLSLLEKKLDSAAKDADERIEK-- 859

Query: 70  QIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQL 119
                 +    EETQ +L + +K  +E +DAL++ ++ ++   A+LK +L
Sbjct: 860 ------VQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRL 903


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 20/88 (22%)

Query: 35  ELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNL 94
           E KE +E K++ ++ + D  D I +A  D                    +EM EE  ++L
Sbjct: 262 EAKEALEAKERYMEEMADTADAIEMATLD--------------------KEMAEERAESL 301

Query: 95  QEEIDALESRVESIQRVLADLKVQLYAK 122
           Q+E++AL+ RV+ +   L  LK ++  K
Sbjct: 302 QQEVEALKERVDELTTDLEILKAEIEEK 329



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 10/110 (9%)

Query: 10   AEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPY 69
            AE + +  ED++ + K  + + +I    EE+     +L  LE   D      D+ +    
Sbjct: 918  AEGLGLKLEDRETVIKELKKSLKIKG--EELSEANVRLSLLEKKLDSAAKDADERIEK-- 973

Query: 70   QIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQL 119
                  +    EETQ +L + +K  +E +DAL++ ++ ++   A+LK +L
Sbjct: 974  ------VQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRL 1017


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 20/88 (22%)

Query: 35  ELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNL 94
           E KE +E K++ ++ + D  D I +A  D                    +EM EE  ++L
Sbjct: 148 EAKEALEAKERYMEEMADTADAIEMATLD--------------------KEMAEERAESL 187

Query: 95  QEEIDALESRVESIQRVLADLKVQLYAK 122
           Q+E++AL+ RV+ +   L  LK ++  K
Sbjct: 188 QQEVEALKERVDELTTDLEILKAEIEEK 215



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 10/110 (9%)

Query: 10  AEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPY 69
           AE + +  ED++ + K  + + +I    EE+     +L  LE   D      D+ +    
Sbjct: 804 AEGLGLKLEDRETVIKELKKSLKIKG--EELSEANVRLSLLEKKLDSAAKDADERIEK-- 859

Query: 70  QIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQL 119
                 +    EETQ +L + +K  +E +DAL++ ++ ++   A+LK +L
Sbjct: 860 ------VQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRL 903


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 20/88 (22%)

Query: 35  ELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNL 94
           E KE +E K++ ++ + D  D I +A  D                    +EM EE  ++L
Sbjct: 282 EAKEALEAKERYMEEMADTADAIEMATLD--------------------KEMAEERAESL 321

Query: 95  QEEIDALESRVESIQRVLADLKVQLYAK 122
           Q+E++AL+ RV+ +   L  LK ++  K
Sbjct: 322 QQEVEALKERVDELTTDLEILKAEIEEK 349



 Score = 36.6 bits (83), Expect = 0.006
 Identities = 27/110 (24%), Positives = 53/110 (48%), Gaps = 10/110 (9%)

Query: 10   AEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPY 69
            AE + +  ED++ + K  + + +I    EE+     +L  LE   D      D+ +    
Sbjct: 938  AEGLGLKLEDRETVIKELKKSLKIKG--EELSEANVRLSLLEKKLDSAAKDADERIEK-- 993

Query: 70   QIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQL 119
                  +    EETQ +L + +K  +E +DAL++ ++ ++   A+LK +L
Sbjct: 994  ------VQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRL 1037


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 22/92 (23%), Positives = 52/92 (56%), Gaps = 5/92 (5%)

Query: 29  NTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFIS--HSQEETQEM 86
           N+S++T++ +E+ +K++ ++ L+     +  A+++   +   I D+ +    SQ+E  + 
Sbjct: 894 NSSQLTKMNDELRLKERDVEELQLK---LTKANENASFLQKSIEDMTVKAEQSQQEAAKK 950

Query: 87  LEEAKKNLQEEIDALESRVESIQRVLADLKVQ 118
            EE KK L+ ++  LE ++E+      +LK +
Sbjct: 951 HEEEKKELERKLSDLEKKMETSHNQCQELKAR 982



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 26/146 (17%), Positives = 62/146 (42%), Gaps = 17/146 (11%)

Query: 5    MKKAAAEDVNVTFEDQQKINKFARNTS--------RITELKEEIEVKKKQLQNLEDACDD 56
            MKK  ++ +    E++  + K    TS         + +L+ E+ V + +  + +     
Sbjct: 1167 MKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 1226

Query: 57   IMLADDDCLMIPYQIGDVFI---------SHSQEETQEMLEEAKKNLQEEIDALESRVES 107
            +   + D + +  ++ ++ +         S S   T    +E ++  + +ID L S +  
Sbjct: 1227 VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVD 1286

Query: 108  IQRVLADLKVQLYAKFGSNINLEADE 133
            +QR   DLK+++     + +N   D+
Sbjct: 1287 LQRKNQDLKMKVEMMSEAALNGNGDD 1312


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 40.4 bits (93), Expect = 4e-04
 Identities = 22/92 (23%), Positives = 52/92 (56%), Gaps = 5/92 (5%)

Query: 29   NTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFIS--HSQEETQEM 86
            N+S++T++ +E+ +K++ ++ L+     +  A+++   +   I D+ +    SQ+E  + 
Sbjct: 929  NSSQLTKMNDELRLKERDVEELQLK---LTKANENASFLQKSIEDMTVKAEQSQQEAAKK 985

Query: 87   LEEAKKNLQEEIDALESRVESIQRVLADLKVQ 118
             EE KK L+ ++  LE ++E+      +LK +
Sbjct: 986  HEEEKKELERKLSDLEKKMETSHNQCQELKAR 1017



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 26/146 (17%), Positives = 62/146 (42%), Gaps = 17/146 (11%)

Query: 5    MKKAAAEDVNVTFEDQQKINKFARNTS--------RITELKEEIEVKKKQLQNLEDACDD 56
            MKK  ++ +    E++  + K    TS         + +L+ E+ V + +  + +     
Sbjct: 1202 MKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 1261

Query: 57   IMLADDDCLMIPYQIGDVFI---------SHSQEETQEMLEEAKKNLQEEIDALESRVES 107
            +   + D + +  ++ ++ +         S S   T    +E ++  + +ID L S +  
Sbjct: 1262 VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVD 1321

Query: 108  IQRVLADLKVQLYAKFGSNINLEADE 133
            +QR   DLK+++     + +N   D+
Sbjct: 1322 LQRKNQDLKMKVEMMSEAALNGNGDD 1347


>gi|5730075 fibrinogen-like 2 precursor [Homo sapiens]
          Length = 439

 Score = 38.9 bits (89), Expect = 0.001
 Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 13/93 (13%)

Query: 31  SRITELKEEIEVKKKQLQNLEDACDDIMLADDD-------CLMIPY-----QIGDVFISH 78
           SRI E+ +E++  K+ + +L+ +C D  L  DD        L++P      ++GD  +  
Sbjct: 73  SRIEEVFKEVQNLKEIVNSLKKSCQDCKLQADDNGDPGRNGLLLPSTGAPGEVGDNRVRE 132

Query: 79  SQEETQEMLEEAKKNLQEEIDALESRVESIQRV 111
            + E  ++  E  KN +EEI+ L  R+E +  V
Sbjct: 133 LESEVNKLSSEL-KNAKEEINVLHGRLEKLNLV 164


>gi|96975038 coiled-coil domain containing 100 [Homo sapiens]
          Length = 986

 Score = 37.0 bits (84), Expect = 0.005
 Identities = 27/119 (22%), Positives = 59/119 (49%), Gaps = 14/119 (11%)

Query: 5   MKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQ-----NLEDACDDIML 59
           +KK  AE   +  + Q+ +    +   ++  ++ E++ +KK+LQ     NL++  D I  
Sbjct: 698 VKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRR 757

Query: 60  ADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQ 118
           A +DC+   +Q+        +    + LEE K  LQ++++  E++ + +++     K Q
Sbjct: 758 AKEDCI---HQV------ELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQ 807


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 36.2 bits (82), Expect = 0.008
 Identities = 29/114 (25%), Positives = 59/114 (51%), Gaps = 18/114 (15%)

Query: 11   EDVNVTFEDQQKI--NKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIP 68
            ED N  F  ++K+  ++ A  +S++ E +E    K K L  + +   ++M++D +  +  
Sbjct: 991  EDQNSKFIKEKKLMEDRIAECSSQLAEEEE----KAKNLAKIRNK-QEVMISDLEERL-- 1043

Query: 69   YQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAK 122
                       +E+T++ LE+AK+ L  E   L+ ++  +Q  + +LK+QL  K
Sbjct: 1044 ---------KKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKK 1088



 Score = 36.2 bits (82), Expect = 0.008
 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 8/90 (8%)

Query: 18   EDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFIS 77
            E +QK+N     +SRI +L+EE    ++Q +  E+A  ++   +   L +  Q+ D    
Sbjct: 1327 ETRQKLNL----SSRIRQLEEEKNSLQEQQEEEEEARKNL---EKQVLALQSQLADTKKK 1379

Query: 78   HSQE-ETQEMLEEAKKNLQEEIDALESRVE 106
               +  T E LEEAKK L ++ +AL  R+E
Sbjct: 1380 VDDDLGTIESLEEAKKKLLKDAEALSQRLE 1409



 Score = 33.9 bits (76), Expect = 0.040
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 12/104 (11%)

Query: 18   EDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFIS 77
            E + K    AR      E KEE E + KQL+      +D+M + DD       +G     
Sbjct: 1480 EKETKALSLARALEEALEAKEEFERQNKQLR---ADMEDLMSSKDD-------VGKNV-- 1527

Query: 78   HSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYA 121
            H  E+++  LE+  + ++ +++ LE  +++ +     L+V + A
Sbjct: 1528 HELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 21/88 (23%), Positives = 47/88 (53%), Gaps = 5/88 (5%)

Query: 24   NKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFIS-----H 78
            ++ A   ++I ELK ++  K+++LQ      DD  L  ++ L +  ++            
Sbjct: 1069 DQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFE 1128

Query: 79   SQEETQEMLEEAKKNLQEEIDALESRVE 106
            S++ ++   E+ K++L EE++AL++ +E
Sbjct: 1129 SEKASRNKAEKQKRDLSEELEALKTELE 1156



 Score = 32.3 bits (72), Expect = 0.12
 Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 13/116 (11%)

Query: 10   AEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACD-DIMLADDDCLMIP 68
            +E   +  E  +K +K       ++ L EE E  KK ++  +DA   +  L D   L+  
Sbjct: 1269 SEGDRLRVELAEKASKLQNELDNVSTLLEEAE--KKGIKFAKDAASLESQLQDTQELLQE 1326

Query: 69   YQIGDVFIS----------HSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLAD 114
                 + +S          +S +E QE  EEA+KNL++++ AL+S++   ++ + D
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDD 1382


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 35.8 bits (81), Expect = 0.011
 Identities = 21/93 (22%), Positives = 51/93 (54%), Gaps = 3/93 (3%)

Query: 21   QKINKFARNTSRITELKEEIEVKKKQLQN-LEDACDDIMLADDDCLMIPYQIGDVF--IS 77
            +++ +  +N   + ++++++EV+K +LQ+ LE+A   +   +   L    +   +   I 
Sbjct: 1516 EQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE 1575

Query: 78   HSQEETQEMLEEAKKNLQEEIDALESRVESIQR 110
                E  E +E+AK+N Q  +D+L++ +++  R
Sbjct: 1576 RKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETR 1608



 Score = 34.7 bits (78), Expect = 0.024
 Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 9/89 (10%)

Query: 23   INKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEE 82
            IN+  +  S +T+L+ E+E   ++ +N E+       A  D  M+  ++        +++
Sbjct: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKK---AITDAAMMAEEL------KKEQD 1776

Query: 83   TQEMLEEAKKNLQEEIDALESRVESIQRV 111
            T   LE  KKN+++ I  L+ R++  +++
Sbjct: 1777 TSAHLERMKKNMEQTIKDLQHRLDEAEQI 1805



 Score = 33.1 bits (74), Expect = 0.069
 Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 24/108 (22%)

Query: 14   NVTFEDQQKI-----NKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIP 68
            N   ED+Q +      K   N +RI EL+EE+E ++     +E    D+           
Sbjct: 1093 NSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDL----------- 1141

Query: 69   YQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLK 116
                    S   EE  E LEEA      +I+  + R    Q++  DL+
Sbjct: 1142 --------SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLE 1181



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 27/136 (19%), Positives = 62/136 (45%), Gaps = 28/136 (20%)

Query: 7    KAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLE--------------- 51
            +A  +++N   ED++++N  A  T++  +L++E    KK + +LE               
Sbjct: 918  EAKVKEMNERLEDEEEMN--AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 975

Query: 52   ---DACDDIMLADDDCLMIPYQIGDVFISHSQ--------EETQEMLEEAKKNLQEEIDA 100
               +  +++   D+    +  +   +  +H Q        E+    L ++K  L++++D 
Sbjct: 976  KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDD 1035

Query: 101  LESRVESIQRVLADLK 116
            LE  +E  ++V  DL+
Sbjct: 1036 LEGSLEQEKKVRMDLE 1051



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 21/112 (18%)

Query: 30   TSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEE 89
            T  I   +E  E KKK  Q L+DA + +   +  C              S E+T+  L+ 
Sbjct: 1379 TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKC-------------SSLEKTKHRLQN 1425

Query: 90   AKKNLQEEID-------ALESRVESIQRVLADLKVQLYAKFGSNINLEADES 134
              ++L  +++       AL+ +  +  ++LA+ K Q Y +  S +     E+
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWK-QKYEESQSELESSQKEA 1476


>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
           sapiens]
          Length = 1002

 Score = 35.4 bits (80), Expect = 0.014
 Identities = 27/126 (21%), Positives = 59/126 (46%), Gaps = 18/126 (14%)

Query: 25  KFARNTSRITELKEEIEVKKKQLQNLEDACDDIM------------LADD-----DCLMI 67
           K      +++ELKE +E+K ++ Q+L+   D  +            L  +     + L++
Sbjct: 583 KLGELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLL 642

Query: 68  PYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNI 127
             Q+ D  +   + + + + E A++ LQE  + LE+  +  Q++ A L +  +   G  +
Sbjct: 643 QTQLVDQ-LQQQEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGL 701

Query: 128 NLEADE 133
           + E +E
Sbjct: 702 DREEEE 707


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 35.4 bits (80), Expect = 0.014
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 2/86 (2%)

Query: 27   ARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEM 86
            A+ T +IT L E +   KK+ Q+ +    ++    DD L     + +  + ++Q+E + +
Sbjct: 1237 AKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDD-LRGEIAVLEATVQNNQDERRAL 1295

Query: 87   LEEAKKNLQEEIDALESRVESIQRVL 112
            LE   K  + EI+ L+++V  +QR L
Sbjct: 1296 LERCLKG-EGEIEKLQTKVLELQRKL 1320



 Score = 28.5 bits (62), Expect = 1.7
 Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 18/93 (19%)

Query: 33   ITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKK 92
            I ELK+  E KKKQ++ L+      +L   +                + + Q+ L +A +
Sbjct: 961  INELKQSSEQKKKQIEALQGELKIAVLQKTEL---------------ENKLQQQLTQAAQ 1005

Query: 93   NL---QEEIDALESRVESIQRVLADLKVQLYAK 122
             L   +E+I  L++  E  Q     L+   Y +
Sbjct: 1006 ELAAEKEKISVLQNNYEKSQETFKQLQSDFYGR 1038


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 35.4 bits (80), Expect = 0.014
 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 10/103 (9%)

Query: 4    TMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDI--MLAD 61
            T  KA+AE +  T+EDQ    K      ++ EL+ ++     Q   L+    ++  +L +
Sbjct: 1288 TRAKASAEKLCRTYEDQLSEAKI-----KVEELQRQLADASTQRGRLQTESGELSRLLEE 1342

Query: 62   DDCLMIPYQIGDVFISHSQEETQEMLEE---AKKNLQEEIDAL 101
             +CL+     G    + S EE +  LEE   AK  L   + AL
Sbjct: 1343 KECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQAL 1385



 Score = 32.0 bits (71), Expect = 0.15
 Identities = 26/104 (25%), Positives = 56/104 (53%), Gaps = 8/104 (7%)

Query: 35   ELKEEIEVKKKQLQNLEDACDDIMLA----DDDCLMIPYQIGDVFISHSQEETQEMLEEA 90
            +L+ +++   ++L++ E+   D+       +D+C  +   I D+ ++ ++ E ++   E 
Sbjct: 963  QLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATEN 1022

Query: 91   K-KNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINLEADE 133
            K KNL EE+ AL+   ES+ R+  + K    A   +  +L+A+E
Sbjct: 1023 KVKNLTEEMAALD---ESVARLTKEKKALQEAHQQALGDLQAEE 1063



 Score = 30.0 bits (66), Expect = 0.58
 Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 8/124 (6%)

Query: 11   EDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQ 70
            E  +VT E ++  +  A    +   L+  +E +++Q + ++    ++  A  +   +  +
Sbjct: 1473 ESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQR---ELEAAQRESRGLGTE 1529

Query: 71   IGDVFISHSQEETQEMLEEAK---KNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNI 127
            +    + H  EE  E LE  K   KNLQEEI  L  +V    + + +L+    A  G   
Sbjct: 1530 L--FRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKS 1587

Query: 128  NLEA 131
             ++A
Sbjct: 1588 EIQA 1591


>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
           sapiens]
          Length = 805

 Score = 35.4 bits (80), Expect = 0.014
 Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 22/110 (20%)

Query: 18  EDQQKINKFARNTSR-ITELK-------EEIEVKKKQLQNLEDACDDIMLADDDCLMIPY 69
           E+++K+ +  +   R I+ LK       E+ + K+++++ LE    D+   DD       
Sbjct: 471 EEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDD------- 523

Query: 70  QIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQL 119
                    SQ    ++LEE  KNLQE +   E ++E I++   D + QL
Sbjct: 524 -------VQSQSLQLQILEEKNKNLQEALIDTEKKLEEIKKQCQDKETQL 566


>gi|18079254 p53 and DNA damage-regulated protein [Homo sapiens]
          Length = 133

 Score = 35.0 bits (79), Expect = 0.018
 Identities = 23/85 (27%), Positives = 48/85 (56%), Gaps = 15/85 (17%)

Query: 33  ITELKEEIEVKKKQLQNLEDACD-----------DIMLADDDCLMIPYQIGDVFISHSQE 81
           + EL EE+   K+Q+ +L+   +           D+ L++D  +M+ +  G++FI     
Sbjct: 16  VEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSED--VMVCF--GNMFIKMPHP 71

Query: 82  ETQEMLEEAKKNLQEEIDALESRVE 106
           ET+EM+E+ + +L +EI+ L  +++
Sbjct: 72  ETKEMIEKDQDHLDKEIEKLRKQLK 96


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 35.0 bits (79), Expect = 0.018
 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 23/110 (20%)

Query: 20   QQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHS 79
            + K+ +         E+  E+  KK+   NLED C  +    DD  +   ++        
Sbjct: 920  EAKVKELTERLEEEEEMNSELVAKKR---NLEDKCSSLKRDIDDLELTLTKV-------- 968

Query: 80   QEETQEMLEEAKKNLQEEIDALESRV-----------ESIQRVLADLKVQ 118
             E+ +   E   KNL EE+ ALE  +           E+ Q+ L DL+V+
Sbjct: 969  -EKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE 1017



 Score = 31.6 bits (70), Expect = 0.20
 Identities = 32/145 (22%), Positives = 72/145 (49%), Gaps = 20/145 (13%)

Query: 5   MKKAAAEDVNVTFEDQQKINK--FARNTSRITELKEEI-----EVKKKQLQNLEDACDDI 57
           +K A AE    T ++  +  K   AR+ +R  EL+E++     E    QLQ ++   +++
Sbjct: 844 LKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQ-VQSETENL 902

Query: 58  MLADDDC-------LMIPYQIGDVFISHSQEETQEMLEEA---KKNLQEEIDALESRVES 107
           M A++ C       +++  ++ +  ++   EE +EM  E    K+NL+++  +L+  ++ 
Sbjct: 903 MDAEERCEGLIKSKILLEAKVKE--LTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDD 960

Query: 108 IQRVLADLKVQLYAKFGSNINLEAD 132
           ++  L  ++ + +A      NL  +
Sbjct: 961 LELTLTKVEKEKHATENKVKNLSEE 985



 Score = 28.1 bits (61), Expect = 2.2
 Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 23/111 (20%)

Query: 7    KAAAEDVNV-TFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCL 65
            +A  +D  V + + Q+KI +     +RI EL+EEIE +      +E    D+        
Sbjct: 1095 QAKIDDEQVHSLQFQKKIKELQ---ARIEELEEEIEAEHTLRAKIEKQRSDL-------- 1143

Query: 66   MIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLK 116
                       +   EE  E LEEA      +I+  + R    Q++  DL+
Sbjct: 1144 -----------ARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 35.0 bits (79), Expect = 0.018
 Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 19/113 (16%)

Query: 20  QQKINKFARNTSRITELKEEIEVKKKQLQNLEDA----------CDDIMLADDDCLMIPY 69
           ++KIN   +   +I  L+E++  K KQL NL+D            D  +   ++ L    
Sbjct: 538 ERKINVLQK---KIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKE 594

Query: 70  QIGDVFISHSQEETQEMLEEAK------KNLQEEIDALESRVESIQRVLADLK 116
           +I +      + + +E LEE +      K+L+E+++AL++ +   +  L DLK
Sbjct: 595 RIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK 647



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 9/89 (10%)

Query: 31  SRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEA 90
           ++I +LK+E+  K+ +L  L+   + +   + DC     Q  +V      +E+    E+ 
Sbjct: 434 TKIDQLKQELSKKESELLALQTKLETLSNQNSDC----KQHIEVL-----KESLTAKEQR 484

Query: 91  KKNLQEEIDALESRVESIQRVLADLKVQL 119
              LQ E+DAL  R+E  +  L     QL
Sbjct: 485 AAILQTEVDALRLRLEEKESFLNKKTKQL 513


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 34.7 bits (78), Expect = 0.024
 Identities = 26/114 (22%), Positives = 57/114 (50%), Gaps = 5/114 (4%)

Query: 18   EDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFIS 77
            + +QKI + A   + + EL+ +++ +KKQLQ      + +        ++  +I D +  
Sbjct: 1109 QKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIAD-YER 1167

Query: 78   HSQEETQEMLEEAKK--NLQEEIDALESRVESIQRVLADLK--VQLYAKFGSNI 127
              +E  Q++  +  K  +L++EI   + + E++Q  +  L+  VQ Y +  + I
Sbjct: 1168 LMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKI 1221


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score = 34.7 bits (78), Expect = 0.024
 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 4/109 (3%)

Query: 24  NKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVF---ISHSQ 80
           N+ +  T  I  ++ EIE  KKQ  NLE A  D     D+ L       D     +  ++
Sbjct: 346 NEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAK 405

Query: 81  EETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINL 129
           EE   ML E ++ +  ++ AL+  + + +++L   + ++  +F S +++
Sbjct: 406 EELARMLREYQELMSLKL-ALDMEIATYRKLLESEECRMSGEFPSPVSI 453


>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
           b [Homo sapiens]
          Length = 882

 Score = 34.7 bits (78), Expect = 0.024
 Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 8/118 (6%)

Query: 23  INKFARNTSRITELKEEIEVKKKQLQNLED--ACDDIMLADDDCLMIPYQ--IGDVFISH 78
           I +      R++E+ +++  +   +Q L +  AC + ++ + +  +I  Q        +H
Sbjct: 87  IQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATH 146

Query: 79  ----SQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINLEAD 132
               S  E  E +++  K+LQE+ D+    VE  Q ++ DL+V+L A      N+  D
Sbjct: 147 RYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKD 204



 Score = 27.3 bits (59), Expect = 3.8
 Identities = 24/106 (22%), Positives = 54/106 (50%), Gaps = 12/106 (11%)

Query: 33  ITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKK 92
           + E  + +E K++QL+  ++  + +M  + + L   ++  D  +    +E    LEE  +
Sbjct: 464 LQEATKLLEDKREQLKKSKEH-EKLMEGELEALRQEFKKKDKTL----KENSRKLEEENE 518

Query: 93  NLQEEIDALESRVES-------IQRVLADLKVQLYAKFGSNINLEA 131
           NL+ E+    +++ES        Q+V+ DL  ++  +  S ++L+A
Sbjct: 519 NLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQA 564


>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
           a [Homo sapiens]
          Length = 1007

 Score = 34.7 bits (78), Expect = 0.024
 Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 8/118 (6%)

Query: 23  INKFARNTSRITELKEEIEVKKKQLQNLED--ACDDIMLADDDCLMIPYQ--IGDVFISH 78
           I +      R++E+ +++  +   +Q L +  AC + ++ + +  +I  Q        +H
Sbjct: 232 IQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATH 291

Query: 79  ----SQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINLEAD 132
               S  E  E +++  K+LQE+ D+    VE  Q ++ DL+V+L A      N+  D
Sbjct: 292 RYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKD 349



 Score = 27.3 bits (59), Expect = 3.8
 Identities = 24/106 (22%), Positives = 54/106 (50%), Gaps = 12/106 (11%)

Query: 33  ITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKK 92
           + E  + +E K++QL+  ++  + +M  + + L   ++  D  +    +E    LEE  +
Sbjct: 609 LQEATKLLEDKREQLKKSKEH-EKLMEGELEALRQEFKKKDKTL----KENSRKLEEENE 663

Query: 93  NLQEEIDALESRVES-------IQRVLADLKVQLYAKFGSNINLEA 131
           NL+ E+    +++ES        Q+V+ DL  ++  +  S ++L+A
Sbjct: 664 NLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQA 709


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 34.7 bits (78), Expect = 0.024
 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 17/119 (14%)

Query: 18   EDQQKINKFARNTS-RITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFI 76
            E ++K+ KFA++   +I EL+EE +  + ++    D   + M              +  +
Sbjct: 1673 EMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECM--------------ETLL 1718

Query: 77   SH--SQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINLEADE 133
            S   S +E  E ++   + L ++  +L S  +S+   + DLK Q+        NLEA E
Sbjct: 1719 SSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATE 1777



 Score = 34.3 bits (77), Expect = 0.031
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 22/119 (18%)

Query: 6    KKAAAE--DVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDD 63
            KKA AE     V  +D Q         +R+  L + +++KK+   N E     +   D+D
Sbjct: 2071 KKAQAELASFKVLLDDTQS------EAARV--LADNLKLKKELQSNKESVKSQMKQKDED 2122

Query: 64   CLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAK 122
                        +    E+ +E   + KKN+QE++DAL      ++  + +++V L  K
Sbjct: 2123 ------------LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKK 2169



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 24/127 (18%)

Query: 6    KKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCL 65
            K+AA   +     +Q+ + K A +T    + KE  E + KQLQ   + C+          
Sbjct: 1418 KEAALTKIQTEIIEQEDLIK-ALHTQLEMQAKEHDE-RIKQLQ--VELCE--------MK 1465

Query: 66   MIPYQIGDVFISHSQEETQEMLEEA----------KKNLQEEIDALESRVESIQRVLADL 115
              P +IG+   S ++++ Q  L+ A           K+LQEE+      +E + + LAD+
Sbjct: 1466 QKPEEIGEE--SRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADV 1523

Query: 116  KVQLYAK 122
            + Q+ A+
Sbjct: 1524 ESQVSAQ 1530



 Score = 28.9 bits (63), Expect = 1.3
 Identities = 23/94 (24%), Positives = 45/94 (47%), Gaps = 12/94 (12%)

Query: 20   QQKINKFARNTSRITELKEEIEV----KKKQLQNLEDACDDIMLADDDCLMIPYQIGDVF 75
            Q+K++   R    + E   EI+V    K K++Q L++  D  +                 
Sbjct: 2142 QEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQ--------LAAFTKS 2193

Query: 76   ISHSQEETQEMLEEAKKNLQEEIDALESRVESIQ 109
            +S  Q++   +++EAKK  ++  DA++S+ E I+
Sbjct: 2194 MSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIR 2227



 Score = 27.7 bits (60), Expect = 2.9
 Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 22/126 (17%)

Query: 14  NVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLM------- 66
           N T ED Q+   +A     + ELK+ I  K  QLQ  ++A  +   A D+ +        
Sbjct: 44  NTTQEDVQERLAYAEQL--VVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAK 101

Query: 67  ------------IPYQIGDVFISHSQEETQEMLEEAKKNLQE-EIDALESRVESIQRVLA 113
                       +  Q G V  +  Q E Q    +     +E EI+ ++ +++  + +++
Sbjct: 102 AKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELIS 161

Query: 114 DLKVQL 119
            L+ QL
Sbjct: 162 TLQAQL 167



 Score = 26.2 bits (56), Expect = 8.4
 Identities = 20/100 (20%), Positives = 51/100 (51%), Gaps = 5/100 (5%)

Query: 22   KINKFARNTS---RITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISH 78
            K +K A +T    +  EL++E E+  +  +N+ +  + I    +       ++     S 
Sbjct: 1594 KSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRST 1653

Query: 79   --SQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLK 116
              +++ET++ L+EA++ ++E  + +    +S Q+ + +L+
Sbjct: 1654 EANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE 1693


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 34.3 bits (77), Expect = 0.031
 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 22/97 (22%)

Query: 33  ITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKK 92
           I  L+ EI+  KKQ+ NL+ +                      IS +++  +  L++AK 
Sbjct: 405 IQRLRSEIDNVKKQISNLQQS----------------------ISDAEQRGENALKDAKN 442

Query: 93  NLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINL 129
            L +  DAL+   E + R+L D +  +  K   ++ +
Sbjct: 443 KLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEI 479


>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
          Length = 1113

 Score = 34.3 bits (77), Expect = 0.031
 Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 13/141 (9%)

Query: 4   TMKKAAAEDVNVTFED-----QQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIM 58
           T KK   E    T  D     Q+K        + IT+L+  +++K ++LQ+L++  D + 
Sbjct: 485 TAKKMTLESSERTISDLTTSLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLR 544

Query: 59  LADDDCLMIPYQI--GDVFISHSQEETQEMLEEAKKN------LQEEIDALESRVESIQR 110
               +C  +  Q+   D  I   +++ + M +   ++      +Q E   LE  +   + 
Sbjct: 545 NVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRM 604

Query: 111 VLADLKVQLYAKFGSNINLEA 131
            L +LK+    K      LEA
Sbjct: 605 ELKELKILKDKKDAKIRELEA 625



 Score = 26.6 bits (57), Expect = 6.4
 Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 4/42 (9%)

Query: 81  EETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAK 122
           E T+EML    + + EE+ A +  +ES +R ++DL   L  K
Sbjct: 471 ESTKEML----RKVVEELTAKKMTLESSERTISDLTTSLQEK 508


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 34.3 bits (77), Expect = 0.031
 Identities = 30/121 (24%), Positives = 56/121 (46%), Gaps = 11/121 (9%)

Query: 7   KAAAEDVNVTFEDQQKI-NKFARNTSRIT-ELKEEIEVKKKQLQNLEDACDDIMLADDDC 64
           K   +D+ +  E+Q+ +  K  R  + +   LKEE+    +++  L++  D  + A  + 
Sbjct: 736 KQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRES 795

Query: 65  LMIPYQIGDVFISHSQEETQE---------MLEEAKKNLQEEIDALESRVESIQRVLADL 115
           +    +  +V  S S    Q+         +L+E  + LQ   + LE RV  +QR + DL
Sbjct: 796 VEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDL 855

Query: 116 K 116
           K
Sbjct: 856 K 856



 Score = 30.8 bits (68), Expect = 0.34
 Identities = 22/89 (24%), Positives = 47/89 (52%), Gaps = 8/89 (8%)

Query: 31   SRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQ-----E 85
            +RI EL++ +E +++   NL+ +   +     + +M   Q+ D  +S + ++ Q     +
Sbjct: 1153 ARIAELEDRLESEERDRANLQLSNRRLERKVKELVM---QVDDEHLSLTDQKDQLSLRLK 1209

Query: 86   MLEEAKKNLQEEIDALESRVESIQRVLAD 114
             ++   +  +EEID LES  + +QR L +
Sbjct: 1210 AMKRQVEEAEEEIDRLESSKKKLQRELEE 1238


>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
          Length = 872

 Score = 34.3 bits (77), Expect = 0.031
 Identities = 20/86 (23%), Positives = 45/86 (52%), Gaps = 2/86 (2%)

Query: 31  SRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEA 90
           ++I  L+ E+E  KKQ +    A D+++   D  ++    +  V  +  Q +  ++ E+A
Sbjct: 356 NQIVGLEREVEASKKQAELDRKAMDELLRERD--ILNKNMLKAVNATQKQTDLVKLHEQA 413

Query: 91  KKNLQEEIDALESRVESIQRVLADLK 116
           K+NL+ EI   +   +  ++++  L+
Sbjct: 414 KRNLEGEIQNYKDEAQKQRKIIFHLE 439



 Score = 26.9 bits (58), Expect = 4.9
 Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 11/73 (15%)

Query: 20  QQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHS 79
           QQ+I +     SR    KE++E + KQ+Q           AD D      +    ++  S
Sbjct: 201 QQEIQQRQNEASREFRKKEKLEKELKQIQ-----------ADMDSRQTEIKALQQYVQKS 249

Query: 80  QEETQEMLEEAKK 92
           +EE Q++ ++ K+
Sbjct: 250 KEELQKLEQQLKE 262


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 33.9 bits (76), Expect = 0.040
 Identities = 27/129 (20%), Positives = 62/129 (48%), Gaps = 4/129 (3%)

Query: 6    KKAAAEDVNVTFEDQQKINK--FARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDD 63
            +K  A    V F +Q  ++K   +R  ++I EL+  +E ++ Q++ LE       L ++ 
Sbjct: 1795 EKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLAS--RLKENM 1852

Query: 64   CLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKF 123
              +   +   +   + ++E  + L+   ++ +EE+  L  +     R   +L++ L +  
Sbjct: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1912

Query: 124  GSNINLEAD 132
             +N +L+AD
Sbjct: 1913 AANQSLQAD 1921


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 33.9 bits (76), Expect = 0.040
 Identities = 27/129 (20%), Positives = 62/129 (48%), Gaps = 4/129 (3%)

Query: 6    KKAAAEDVNVTFEDQQKINK--FARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDD 63
            +K  A    V F +Q  ++K   +R  ++I EL+  +E ++ Q++ LE       L ++ 
Sbjct: 1795 EKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLAS--RLKENM 1852

Query: 64   CLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKF 123
              +   +   +   + ++E  + L+   ++ +EE+  L  +     R   +L++ L +  
Sbjct: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1912

Query: 124  GSNINLEAD 132
             +N +L+AD
Sbjct: 1913 AANQSLQAD 1921


>gi|239754018 PREDICTED: hypothetical protein LOC100129791 [Homo
           sapiens]
          Length = 338

 Score = 33.5 bits (75), Expect = 0.052
 Identities = 23/101 (22%), Positives = 51/101 (50%), Gaps = 12/101 (11%)

Query: 19  DQQKINKFARNTSRITELKEEIEVKKKQLQNLE---DACDDIMLADDDCLMIPYQIGDVF 75
           D  ++ +     S  +EL+E+I+ K K+++N E   + C   +   + CL    ++    
Sbjct: 38  DFDELREAGFRRSNYSELREDIQTKGKEVENFEKNLEECITRITNTEKCLKELMEL---- 93

Query: 76  ISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLK 116
               + + +E+ EE  ++L+   D LE RV +++  + ++K
Sbjct: 94  ----KTKARELCEEC-RSLRSRCDQLEERVSAMEDEMNEMK 129


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.327 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,908,221
Number of Sequences: 37866
Number of extensions: 152819
Number of successful extensions: 2066
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 271
Number of HSP's that attempted gapping in prelim test: 1524
Number of HSP's gapped (non-prelim): 823
length of query: 134
length of database: 18,247,518
effective HSP length: 91
effective length of query: 43
effective length of database: 14,801,712
effective search space: 636473616
effective search space used: 636473616
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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