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Search of human proteins with 38455427
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
sapiens]
(539 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ... 1025 0.0
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom... 348 5e-96
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 306 3e-83
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 300 2e-81
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 297 2e-80
gi|57863257 T-complex protein 1 isoform a [Homo sapiens] 276 3e-74
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] 261 1e-69
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 254 1e-67
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 240 3e-63
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 239 6e-63
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom... 235 7e-62
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho... 179 4e-45
gi|57863259 T-complex protein 1 isoform b [Homo sapiens] 152 6e-37
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom... 150 2e-36
gi|7657253 T-complex protein 1 [Homo sapiens] 135 9e-32
gi|41399285 chaperonin [Homo sapiens] 82 1e-15
gi|31542947 chaperonin [Homo sapiens] 82 1e-15
gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens] 62 1e-09
gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens] 62 1e-09
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens] 45 2e-04
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens] 34 0.30
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 33 0.66
gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens] 33 0.66
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 32 1.1
gi|47519562 reticulon 4 isoform E [Homo sapiens] 32 1.5
gi|24431935 reticulon 4 isoform A [Homo sapiens] 32 1.5
gi|33695153 guanine nucleotide binding protein (G protein), alph... 31 2.5
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 31 2.5
gi|31542779 tripartite motif family-like 1 [Homo sapiens] 31 2.5
gi|38348396 hypothetical protein LOC375307 [Homo sapiens] 31 3.3
>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
sapiens]
Length = 539
Score = 1025 bits (2651), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 1 MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKM 60
MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKM
Sbjct: 1 MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKM 60
Query: 61 IQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSC 120
IQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSC
Sbjct: 61 IQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSC 120
Query: 121 TKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQYS 180
TKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQYS
Sbjct: 121 TKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQYS 180
Query: 181 SLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGITR 240
SLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGITR
Sbjct: 181 SLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGITR 240
Query: 241 VEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLI 300
VEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLI
Sbjct: 241 VEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLI 300
Query: 301 QKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAE 360
QKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAE
Sbjct: 301 QKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAE 360
Query: 361 LAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRA 420
LAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRA
Sbjct: 361 LAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRA 420
Query: 421 LIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTEL 480
LIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTEL
Sbjct: 421 LIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTEL 480
Query: 481 RNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNTR 539
RNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNTR
Sbjct: 481 RNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNTR 539
>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
sapiens]
Length = 541
Score = 348 bits (894), Expect = 5e-96
Identities = 201/505 (39%), Positives = 314/505 (62%), Gaps = 12/505 (2%)
Query: 36 SNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELS 95
S+I AAKAVA+ +RTSLGP G+DKM+ D GDVT+TNDGATIL M V H A+++VELS
Sbjct: 36 SHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELS 95
Query: 96 KAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPV 155
K+QD E GDGTT VV++AG+LL+ +LL +GIHP I++ +++A IE L +S V
Sbjct: 96 KSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSV 155
Query: 156 --ELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKK 213
++ D E L+ +A T+L SKVV+ ++ ++VNAV+ V D VD IK+ K
Sbjct: 156 LVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVAD-MERRDVDFELIKVEGK 214
Query: 214 LGGTIDDCELVEGLVLTQKVSNSGITR-VEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQM 272
+GG ++D +L++G+++ + S+ + + VE AKI ++ PK +++ V+
Sbjct: 215 VGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDY 274
Query: 273 DRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIERED 332
+ + E+ +++QIK+TG N+ + Q D A H L + + ++ + +
Sbjct: 275 KALQKYEKEKFEEMIQQIKETGANLAICQWGF-----DDEANHLLLQNNLPAVRWVGGPE 329
Query: 333 IEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGS-GKLLKITGCASPGKTVTIVVR 391
IE I G + V + TA+ LG A L +E++ + K+L I C + + VTI +R
Sbjct: 330 IELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKN-SRAVTIFIR 388
Query: 392 GSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCV 451
G NK++IEEA+RS+HDALCVIR L++ ++ GGGA EI AL +++ + +E Y +
Sbjct: 389 GGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAM 448
Query: 452 RAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTA-GINVRKGGISNILEELVVQ 510
RAFADA+EVIP L+EN+G+NPI T+TE+R R + A GI+ G +++ ++ V++
Sbjct: 449 RAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIE 508
Query: 511 PLLVSVSALTLATETVRSILKIDDV 535
L+ ++LAT+ VR ILKIDD+
Sbjct: 509 TLIGKKQQISLATQMVRMILKIDDI 533
>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
sapiens]
Length = 545
Score = 306 bits (784), Expect = 3e-83
Identities = 178/515 (34%), Positives = 302/515 (58%), Gaps = 10/515 (1%)
Query: 27 RDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHP 86
R+ +++ NI+AAK +AD IRT LGPK M KM+ D G + +TNDG IL+++QV HP
Sbjct: 16 RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75
Query: 87 AARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIE 146
AA+ ++E+S+ QD E GDGTTSV+I+AG +L L++ +HPT++ +++KAL+ I
Sbjct: 76 AAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 135
Query: 147 ILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKV-IDPATATSVDL 205
L +S PV++SD + +LN +S+ +K +S++SSL ++++AV V + +D+
Sbjct: 136 TLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDI 195
Query: 206 RDIKIVKKL-GGTIDDCELVEGLVLTQKVSNSGITR-VEKAKIGLIQFCLSAPKTDMDNQ 263
+ V+K+ GG I+D ++ G+++ + V++ + R ++ +I L+ L K +
Sbjct: 196 KKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTD 255
Query: 264 IVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIM 323
I ++ R+L+ E YI L + I + +V++ +K I SDLA H+L + I
Sbjct: 256 IEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGI-----SDLAQHYLMRANIT 310
Query: 324 VIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPG 383
I+ + + D I + G + V+ ++ D +G+ E+ G IT C P
Sbjct: 311 AIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDP- 369
Query: 384 KTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTL 443
K TI++RG++K ++ E ER++ DA+ V R ++ L+ GGGA E+ +A LTE S+ +
Sbjct: 370 KACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAM 429
Query: 444 SGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE-KTAGINVRKGGISN 502
+G+E + RA A A+EVIP TL +N G + I +T LR +H Q +T G+N G + +
Sbjct: 430 TGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVD 489
Query: 503 ILEELVVQPLLVSVSALTLATETVRSILKIDDVVN 537
+ E + +PL V + A ET +L+IDD+V+
Sbjct: 490 MKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVS 524
>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
sapiens]
Length = 544
Score = 300 bits (768), Expect = 2e-81
Identities = 177/515 (34%), Positives = 301/515 (58%), Gaps = 11/515 (2%)
Query: 27 RDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHP 86
R+ +++ NI+AAK +AD IRT LGPK M KM+ D G + +TNDG IL+++QV HP
Sbjct: 16 RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75
Query: 87 AARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIE 146
AA+ ++E+S+ QD E GDGTTSV+I+ G +L L++ +HPT++ +++KAL+ I
Sbjct: 76 AAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 134
Query: 147 ILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKV-IDPATATSVDL 205
L +S PV++SD + +LN +S+ +K +S++SSL ++++AV V + +D+
Sbjct: 135 TLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDI 194
Query: 206 RDIKIVKKL-GGTIDDCELVEGLVLTQKVSNSGITR-VEKAKIGLIQFCLSAPKTDMDNQ 263
+ V+K+ GG I+D ++ G+++ + V++ + R ++ +I L+ L K +
Sbjct: 195 KKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTD 254
Query: 264 IVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIM 323
I ++ R+L+ E YI L + I + +V++ +K I SDLA H+L + I
Sbjct: 255 IEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGI-----SDLAQHYLMRANIT 309
Query: 324 VIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPG 383
I+ + + D I + G + V+ ++ D +G+ E+ G IT C P
Sbjct: 310 AIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDP- 368
Query: 384 KTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTL 443
K TI++RG++K ++ E ER++ DA+ V R ++ L+ GGGA E+ +A LTE S+ +
Sbjct: 369 KACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAM 428
Query: 444 SGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE-KTAGINVRKGGISN 502
+G+E + RA A A+EVIP TL +N G + I +T LR +H Q +T G+N G + +
Sbjct: 429 TGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVD 488
Query: 503 ILEELVVQPLLVSVSALTLATETVRSILKIDDVVN 537
+ E + +PL V + A ET +L+IDD+V+
Sbjct: 489 MKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVS 523
>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
sapiens]
Length = 543
Score = 297 bits (760), Expect = 2e-80
Identities = 177/510 (34%), Positives = 290/510 (56%), Gaps = 22/510 (4%)
Query: 36 SNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELS 95
SNISA + +A+A+RT+LGP+GMDK+I DG+G TI+NDGATILK + V+HPAA+ LV+++
Sbjct: 24 SNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHPAAKTLVDIA 83
Query: 96 KAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESF----QKALEKGIEILTDM 151
K+QD E GDGTTSV ++A L +++G+HP II +F Q A+ K EI +
Sbjct: 84 KSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAVTV 143
Query: 152 SRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIV 211
+ ++ R+ L A T+L+SK++SQ + + M V+AVM + D + L+ I I
Sbjct: 144 KKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDD-----LLQLKMIGIK 198
Query: 212 KKLGGTIDDCELVEGLVLTQKVSNSGI----TRVEKAKIGLIQFCLSAPKTDMDN-QIVV 266
K GG ++D +LV G+ + S +G + KI L+ L K + DN +I V
Sbjct: 199 KVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL-KAEKDNAEIRV 257
Query: 267 SDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIK 326
++ E + + +++I +G V+L + I D+A + +
Sbjct: 258 HTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPI-----GDVATQYFADRDMFCAG 312
Query: 327 DIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTV 386
+ ED++ G ++ +AD+LG ++ EE + G + TGC KT
Sbjct: 313 RVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGE-RYNFFTGCPK-AKTC 370
Query: 387 TIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGM 446
T ++RG + +EE ERS+HDA+ ++R +K +++AGGGA E+EL+ L +YSRT+ G
Sbjct: 371 TFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGK 430
Query: 447 ESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEE 506
+ + A+A A+E+IP L +NAG + + + +LR RHAQG G+++ I++ E
Sbjct: 431 QQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEA 490
Query: 507 LVVQPLLVSVSALTLATETVRSILKIDDVV 536
V +P +V ++ALT A+E I+ +D+ +
Sbjct: 491 FVWEPAMVRINALTAASEAACLIVSVDETI 520
>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
Length = 556
Score = 276 bits (707), Expect = 3e-74
Identities = 173/532 (32%), Positives = 296/532 (55%), Gaps = 27/532 (5%)
Query: 24 YQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQV 83
+ DR IR N+ AA ++A+ +++SLGP G+DKM+ D GDVTITNDGATILK ++V
Sbjct: 8 FGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEV 67
Query: 84 LHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEK 143
HPAA++L EL+ QD E GDGTTSVVIIA LL + +L+++ IHPT + ++ A ++
Sbjct: 68 EHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKE 127
Query: 144 GIEILTD-MSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVM--KVIDPATA 200
+ + + + + R+ L+N+A TS++SK++ + M V+AV+ K D
Sbjct: 128 AVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQ 187
Query: 201 TSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGI-TRVEKAKIGLIQFCLSAPKTD 259
+ + I+K G + + L+ G L V + G+ R+ AKI + F L K
Sbjct: 188 PRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMK 247
Query: 260 MDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNK 319
+ Q+V++D ++D++ + E +++I TG NV+L I D+ L + +
Sbjct: 248 LGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGI-----DDMCLKYFVE 302
Query: 320 MKIMVIKDIEREDIEFICKTIGTKPVAHI------DQFTADMLGSA-ELAEEVNLNGSGK 372
M ++ + + D++ I K G ++ + + F A MLG A E+ +E +
Sbjct: 303 AGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELI 362
Query: 373 LLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIEL 432
L+K T + + +I++RG+N + +E ERS+HDALCV++ +++ ++++ GGGA E L
Sbjct: 363 LIKNTKART---SASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAAL 419
Query: 433 ALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE---- 488
++ L Y+ ++ E + FA ++ VIP+TLA NA + V +LR H + +
Sbjct: 420 SIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPE 479
Query: 489 ----KTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVV 536
K G+++ G + + V +P +V V +L ATE +IL+IDD++
Sbjct: 480 RKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLI 531
>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
Length = 535
Score = 261 bits (666), Expect = 1e-69
Identities = 164/517 (31%), Positives = 284/517 (54%), Gaps = 18/517 (3%)
Query: 26 DRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVT--ITNDGATILKQMQV 83
D ++ R ++ A A+ D ++++LGPKGMDK++ D + +TNDGATILK + V
Sbjct: 17 DEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGV 76
Query: 84 LHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEK 143
+PAA++LV++S+ QD E GDGTTSV ++A LL L+ K IHP I +++A +
Sbjct: 77 DNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKA 136
Query: 144 GIEILTDMS---RPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATA 200
E L + E+ R+ L+N A T+L+SK+++ + + ++V AV+++
Sbjct: 137 AREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRL-----K 191
Query: 201 TSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGITRVEKAKIGLIQFCLSAPKTDM 260
S +L I I+KKLGG++ D L EG +L +K+ + R+E AKI + + K +
Sbjct: 192 GSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKI 251
Query: 261 -DNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNK 319
+++ V A++ + E+ + V++I K G N I R + +
Sbjct: 252 FGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCF-----INRQLIYNYPEQLFGA 306
Query: 320 MKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGC 379
+M I+ + +E + G + + D LGS +L EEV + G KL+ +G
Sbjct: 307 AGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMI-GEDKLIHFSGV 365
Query: 380 ASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEY 439
A G+ TIV+RG+ + +++EAERS+HDALCV+ VK + GGG E+ +A +T+
Sbjct: 366 AL-GEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQL 424
Query: 440 SRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGG 499
+ G E+ + ++A A+ ++P+ +A+NAG + V +LR H++G TAG+++R+G
Sbjct: 425 ANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGT 484
Query: 500 ISNILEELVVQPLLVSVSALTLATETVRSILKIDDVV 536
I ++ + + V L A E IL++D+++
Sbjct: 485 IGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNII 521
>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
sapiens]
Length = 507
Score = 254 bits (650), Expect = 1e-67
Identities = 152/462 (32%), Positives = 266/462 (57%), Gaps = 10/462 (2%)
Query: 80 QMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQK 139
++QV HPAA+ ++E+S+ QD E GDGTTSV+I+AG +L L++ +HPT++ +++K
Sbjct: 31 KIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRK 90
Query: 140 ALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKV-IDPA 198
AL+ I L +S PV++SD + +LN +S+ +K +S++SSL ++++AV V +
Sbjct: 91 ALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEEN 150
Query: 199 TATSVDLRDIKIVKKL-GGTIDDCELVEGLVLTQKVSNSGITR-VEKAKIGLIQFCLSAP 256
+D++ V+K+ GG I+D ++ G+++ + V++ + R ++ +I L+ L
Sbjct: 151 GRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYK 210
Query: 257 KTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHF 316
K + I ++ R+L+ E YI L + I + +V++ +K I SDLA H+
Sbjct: 211 KGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGI-----SDLAQHY 265
Query: 317 LNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKI 376
L + I I+ + + D I + G + V+ ++ D +G+ E+ G I
Sbjct: 266 LMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFI 325
Query: 377 TGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRL 436
T C P K TI++RG++K ++ E ER++ DA+ V R ++ L+ GGGA E+ +A L
Sbjct: 326 TDCKDP-KACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHAL 384
Query: 437 TEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE-KTAGINV 495
TE S+ ++G+E + RA A A+EVIP TL +N G + I +T LR +H Q +T G+N
Sbjct: 385 TEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNG 444
Query: 496 RKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVN 537
G + ++ E + +PL V + A ET +L+IDD+V+
Sbjct: 445 ETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVS 486
>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
Length = 530
Score = 240 bits (612), Expect = 3e-63
Identities = 160/510 (31%), Positives = 272/510 (53%), Gaps = 20/510 (3%)
Query: 37 NISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSK 96
NI AA+ + D +RT+LGPKG KM+ G GD+ +T DG +L +MQ+ HP A ++ +++
Sbjct: 23 NICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVAT 82
Query: 97 AQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVE 156
AQD GDGTTS V+I G LL + +G+HP II+E F+ A K +E+L ++ E
Sbjct: 83 AQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKE 142
Query: 157 LSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGG 216
+ R+ LL+ A TSL +KV ++ + +L+ + V++V+ V P + + +I +K G
Sbjct: 143 MK-RKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLG 201
Query: 217 TIDDCELVEGLVLTQKVSNSGI-TRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRV 275
T D +L++GLVL + + RVE A I + L KT++++ + +++
Sbjct: 202 T--DTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKL 259
Query: 276 LREERAYILNLVKQI---KKTGCN------VLLIQKSILRDALSDLALHFLNKMKIMVIK 326
++ ER +I + V++I K C V++ QK I +L LA H I+ ++
Sbjct: 260 VKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKH-----GIVALR 314
Query: 327 DIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTV 386
+R ++E + G V + T D LG A L E L G K I C +P +V
Sbjct: 315 RAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTL-GEEKFTFIEECVNP-CSV 372
Query: 387 TIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGM 446
T++V+G NK + + + +I D L I+ ++ ++ G GA E+ +A L Y ++ G
Sbjct: 373 TLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGR 432
Query: 447 ESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEE 506
V+AFADA+ +IP LA+NAG +P T+ +++ H + ++ G+++ G +
Sbjct: 433 ARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADA 492
Query: 507 LVVQPLLVSVSALTLATETVRSILKIDDVV 536
V V L T +IL +D+++
Sbjct: 493 GVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
sapiens]
Length = 548
Score = 239 bits (609), Expect = 6e-63
Identities = 149/508 (29%), Positives = 270/508 (53%), Gaps = 18/508 (3%)
Query: 35 FSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVEL 94
+ NI A K +A RT+ GP GM+KM+ + + +TND ATIL++++V HPAA+M+V
Sbjct: 30 YRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMA 89
Query: 95 SKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDM--S 152
S Q+ E GDGT V++ AG+LL+ +LL+ G+ + + E ++ A K EIL ++
Sbjct: 90 SHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNLVCC 149
Query: 153 RPVELSDRETLLNSATTSLNSKVVSQYSS--LLSPMSVNAVMKVIDPATATSVDLRDIKI 210
L D + + + TS+ SK QY + L+ + A + + + +VD +I++
Sbjct: 150 SAKNLRDIDEVSSLLRTSIMSK---QYGNEVFLAKLIAQACVSIFPDSGHFNVD--NIRV 204
Query: 211 VKKLGGTIDDCELVEGLVLTQKVSNSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYA 270
K LG I ++ G+V +K + +T V+ AKI + T+ +++
Sbjct: 205 CKILGSGISSSSVLHGMVF-KKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAE 263
Query: 271 QMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIER 330
++ + E + VK I TG NV+ + ++D+ALH+ NK IM+++ +
Sbjct: 264 ELMNFSKGEENLMDAQVKAIADTGANVV-----VTGGKVADMALHYANKYNIMLVRLNSK 318
Query: 331 EDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVV 390
D+ +CKT+G + + + +G + + ++ G +++ G TIV+
Sbjct: 319 WDLRRLCKTVGATALPRLTPPVLEEMGHCD-SVYLSEVGDTQVVVFKHEKEDGAISTIVL 377
Query: 391 RGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYC 450
RGS ++++ ER++ D + + L + + L+ GGGA EIELA ++T Y T G+E Y
Sbjct: 378 RGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYA 437
Query: 451 VRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRK--GGISNILEELV 508
++ FA+A E IP LAEN+G+ +++L H +G K G+++ + ++LE +
Sbjct: 438 IKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGI 497
Query: 509 VQPLLVSVSALTLATETVRSILKIDDVV 536
+ L A+ LAT ++L++D ++
Sbjct: 498 LDTYLGKYWAIKLATNAAVTVLRVDQII 525
>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
sapiens]
Length = 531
Score = 235 bits (600), Expect = 7e-62
Identities = 154/510 (30%), Positives = 272/510 (53%), Gaps = 20/510 (3%)
Query: 37 NISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSK 96
NISAA+ + D +RT+LGPKG KM+ G GD+ +T DG +L +MQ+ HP A ++ +++
Sbjct: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
Query: 97 AQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVE 156
AQD GDGTTS V+I G LL + +G+HP II+E F+ A EK ++ L ++ E
Sbjct: 83 AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSRE 142
Query: 157 LSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGG 216
+ DRETL++ A TSL +KV ++ + +L+ V++++ + +DL I+I++
Sbjct: 143 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAI--KKQDEPIDLFMIEIMEMKHK 199
Query: 217 TIDDCELVEGLVLTQKVSNSGI-TRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRV 275
+ D L+ GLVL + + RVE A I L KT++++ + +++
Sbjct: 200 SETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKL 259
Query: 276 LREERAYILNLVKQI---KKTGCN------VLLIQKSILRDALSDLALHFLNKMKIMVIK 326
++ ER +I + VK+I K+ C V++ QK I +L L+K I+ ++
Sbjct: 260 VKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGI-----DPFSLDALSKEGIVALR 314
Query: 327 DIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTV 386
+R ++E + G + D + D LG A L E L G K I C +P ++V
Sbjct: 315 RAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTL-GEEKFTFIEKCNNP-RSV 372
Query: 387 TIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGM 446
T++++G NK + + + ++ D L ++ + ++ G GA E+ +A L ++ ++ G
Sbjct: 373 TLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGR 432
Query: 447 ESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEE 506
V+AFADA+ +IP LA+N+G + T+ +++ H++ + G+++ G E
Sbjct: 433 AQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEV 492
Query: 507 LVVQPLLVSVSALTLATETVRSILKIDDVV 536
V V L T +IL +D+++
Sbjct: 493 GVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
sapiens]
Length = 486
Score = 179 bits (455), Expect = 4e-45
Identities = 136/510 (26%), Positives = 245/510 (48%), Gaps = 65/510 (12%)
Query: 37 NISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSK 96
NISAA+ + D +RT+LGPKG KM+ G GD+ +T DG +L +M
Sbjct: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEM--------------- 67
Query: 97 AQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVE 156
G+HP II+E F+ A EK ++ L ++ E
Sbjct: 68 ------------------------------GLHPRIITEGFEAAKEKALQFLEEVKVSRE 97
Query: 157 LSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGG 216
+ DRETL++ A TSL +KV ++ + +L+ V++++ + +DL I+I++
Sbjct: 98 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAI--KKQDEPIDLFMIEIMEMKHK 154
Query: 217 TIDDCELVEGLVLTQKVSNSGIT-RVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRV 275
+ D L+ GLVL + + RVE A I L KT++++ + +++
Sbjct: 155 SETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKL 214
Query: 276 LREERAYILNLVKQI---KKTGCN------VLLIQKSILRDALSDLALHFLNKMKIMVIK 326
++ ER +I + VK+I K+ C V++ QK I +L L+K I+ ++
Sbjct: 215 VKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGI-----DPFSLDALSKEGIVALR 269
Query: 327 DIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTV 386
+R ++E + G + D + D LG A L E L G K I C +P ++V
Sbjct: 270 RAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTL-GEEKFTFIEKCNNP-RSV 327
Query: 387 TIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGM 446
T++++G NK + + + ++ D L ++ + ++ G GA E+ +A L ++ ++ G
Sbjct: 328 TLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGR 387
Query: 447 ESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEE 506
V+AFADA+ +IP LA+N+G + T+ +++ H++ + G+++ G E
Sbjct: 388 AQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEV 447
Query: 507 LVVQPLLVSVSALTLATETVRSILKIDDVV 536
V V L T +IL +D+++
Sbjct: 448 GVWDNYCVKKQLLHSCTVIATNILLVDEIM 477
>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
Length = 401
Score = 152 bits (385), Expect = 6e-37
Identities = 106/384 (27%), Positives = 196/384 (51%), Gaps = 26/384 (6%)
Query: 171 LNSKVVSQYSSLLSPMSVNAVM--KVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLV 228
++SK++ + M V+AV+ K D + + I+K G + + L+ G
Sbjct: 1 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYA 60
Query: 229 LTQKVSNSGIT-RVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLV 287
L V + G+ R+ AKI + F L K + Q+V++D ++D++ + E +
Sbjct: 61 LNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERI 120
Query: 288 KQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAH 347
++I TG NV+L I D+ L + + M ++ + + D++ I K G ++
Sbjct: 121 QKILATGANVILTTGGI-----DDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILST 175
Query: 348 I------DQFTADMLGSAE-LAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEE 400
+ + F A MLG AE + +E + L+K T + + +I++RG+N + +E
Sbjct: 176 LANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKART---SASIILRGANDFMCDE 232
Query: 401 AERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEV 460
ERS+HDALCV++ +++ ++++ GGGA E L++ L Y+ ++ E + FA ++ V
Sbjct: 233 MERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLV 292
Query: 461 IPSTLAENAGLNPISTVTELRNRHAQGE--------KTAGINVRKGGISNILEELVVQPL 512
IP+TLA NA + V +LR H + + K G+++ G + + V +P
Sbjct: 293 IPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPT 352
Query: 513 LVSVSALTLATETVRSILKIDDVV 536
+V V +L ATE +IL+IDD++
Sbjct: 353 IVKVKSLKFATEAAITILRIDDLI 376
>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
sapiens]
Length = 339
Score = 150 bits (380), Expect = 2e-36
Identities = 96/322 (29%), Positives = 167/322 (51%), Gaps = 13/322 (4%)
Query: 220 DCELVEGLVLTQKVSNSGITRVEKA----KIGLIQFCLSAPKTDMDN-QIVVSDYAQMDR 274
D +LV G+ + S +G K KI L+ L K + DN +I V
Sbjct: 3 DSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELEL-KAEKDNAEIRVHTVEDYQA 61
Query: 275 VLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIE 334
++ E + + +++I +G V+L + I D+A + + + ED++
Sbjct: 62 IVDAEWNILYDKLEKIHHSGAKVVLSKLPI-----GDVATQYFADRDMFCAGRVPEEDLK 116
Query: 335 FICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSN 394
G ++ +AD+LG ++ EE + G + TGC KT T ++RG
Sbjct: 117 RTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGE-RYNFFTGCPK-AKTCTFILRGGA 174
Query: 395 KLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAF 454
+ +EE ERS+HDA+ ++R +K +++AGGGA E+EL+ L +YSRT+ G + + A+
Sbjct: 175 EQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAY 234
Query: 455 ADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLV 514
A A+E+IP L +NAG + + + +LR RHAQG G+++ I++ E V +P +V
Sbjct: 235 AKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAMV 294
Query: 515 SVSALTLATETVRSILKIDDVV 536
++ALT A+E I+ +D+ +
Sbjct: 295 RINALTAASEAACLIVSVDETI 316
>gi|7657253 T-complex protein 1 [Homo sapiens]
Length = 557
Score = 135 bits (340), Expect = 9e-32
Identities = 120/504 (23%), Positives = 220/504 (43%), Gaps = 20/504 (3%)
Query: 36 SNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELS 95
S+++A + +A IR GP G K + KG+ T IL+ +++ HPAA +L E
Sbjct: 35 SSLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLREAG 94
Query: 96 KAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPV 155
+ Q +GDGT VV++ +LL+ +LL+ G+ + E++ A + + L ++
Sbjct: 95 QTQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSLAIQS 154
Query: 156 --ELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNA-VMKVIDPATATSVDLRDIKIVK 212
L D L+S +N+ +S L ++ +K +D S + +
Sbjct: 155 LGPLEDPSWALHSV---MNTHTLSPMDHLTKLVAHACWAIKELD----GSFKPERVGVCA 207
Query: 213 KLGGTIDDCELVEGLVLTQKVSNSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQM 272
GGT++D L+ GL ++ K+ T + A++ L + +S A +
Sbjct: 208 LPGGTLEDSCLLPGLAISGKLCGQMATVLSGARVALFACPFGPAHPNAPATARLSSPADL 267
Query: 273 DRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIERED 332
+ + + V Q+ G NV ++ + + L+ +K I+VI+ +
Sbjct: 268 AQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLT-----LADKYGIVVIQARSWME 322
Query: 333 IEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRG 392
I ++ + + T + + G + L G G + + +T+V+RG
Sbjct: 323 IIYLSEVLDTPLLPRL--LPPQRPGKCQRVYRQEL-GDGLAVVFEWECTGTPALTVVLRG 379
Query: 393 SNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVR 452
+ + AE++++ + L + LI G GA E+ LA L++ L G
Sbjct: 380 ATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSGPAFL 439
Query: 453 AFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPL 512
AFA A++ +P TLAENAGL + E+ H G G+ GI N+ +E V L
Sbjct: 440 AFAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNLLMGVGTE--GIINVAQEGVWDTL 497
Query: 513 LVSVSALTLATETVRSILKIDDVV 536
+V E V ++ +D++V
Sbjct: 498 IVKAQGFRAVAEVVLQLVTVDEIV 521
>gi|41399285 chaperonin [Homo sapiens]
Length = 573
Score = 82.0 bits (201), Expect = 1e-15
Identities = 119/539 (22%), Positives = 230/539 (42%), Gaps = 56/539 (10%)
Query: 31 AQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHP---- 86
A R + +ADA+ ++GPKG +I+ G +T DG T+ K + +
Sbjct: 34 ADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNI 93
Query: 87 AARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIE 146
A+++ +++ + EAGDGTT+ ++A S+ + + KG +P I A++ I
Sbjct: 94 GAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIA 153
Query: 147 ILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLR 206
L S+PV + E + AT S N + +++S +A+ KV T D +
Sbjct: 154 ELKKQSKPV--TTPEEIAQVATISANGD--KEIGNIIS----DAMKKVGRKGVITVKDGK 205
Query: 207 DIKIVKKLGGTIDDCELVEGLVLTQKVSNS---GITRVEKAKIGLIQFCLSAPKTDMDNQ 263
+ D+ E++EG+ + + ++ +K + LS K
Sbjct: 206 TLN---------DELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQS 256
Query: 264 IVVS-DYAQMDR----VLRE--ERAYILNLVKQIKKTGCNVLLI--------QKSILRD- 307
IV + + A R ++ E + + LV K G V+ + +K+ L+D
Sbjct: 257 IVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDM 316
Query: 308 ALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADML----GSAELAE 363
A++ F + + ++D++ D+ + + I TK A + + D E+ E
Sbjct: 317 AIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIE 376
Query: 364 EVNLNGS----GKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKR 419
++++ S KL + S G V + V G++ + + E + + DAL R V++
Sbjct: 377 QLDVTTSEYEKEKLNERLAKLSDGVAV-LKVGGTSDVEVNEKKDRVTDALNATRAAVEE- 434
Query: 420 ALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTE 479
++ GGG + L + + + + +++ T+A+NAG+ V +
Sbjct: 435 GIVLGGGCALLRCIPALDSLT-PANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEK 493
Query: 480 LRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNT 538
+ Q G + G N++E+ ++ P V +AL L V S+L +VV T
Sbjct: 494 I----MQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTAL-LDAAGVASLLTTAEVVVT 547
>gi|31542947 chaperonin [Homo sapiens]
Length = 573
Score = 82.0 bits (201), Expect = 1e-15
Identities = 119/539 (22%), Positives = 230/539 (42%), Gaps = 56/539 (10%)
Query: 31 AQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHP---- 86
A R + +ADA+ ++GPKG +I+ G +T DG T+ K + +
Sbjct: 34 ADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNI 93
Query: 87 AARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIE 146
A+++ +++ + EAGDGTT+ ++A S+ + + KG +P I A++ I
Sbjct: 94 GAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIA 153
Query: 147 ILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLR 206
L S+PV + E + AT S N + +++S +A+ KV T D +
Sbjct: 154 ELKKQSKPV--TTPEEIAQVATISANGD--KEIGNIIS----DAMKKVGRKGVITVKDGK 205
Query: 207 DIKIVKKLGGTIDDCELVEGLVLTQKVSNS---GITRVEKAKIGLIQFCLSAPKTDMDNQ 263
+ D+ E++EG+ + + ++ +K + LS K
Sbjct: 206 TLN---------DELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQS 256
Query: 264 IVVS-DYAQMDR----VLRE--ERAYILNLVKQIKKTGCNVLLI--------QKSILRD- 307
IV + + A R ++ E + + LV K G V+ + +K+ L+D
Sbjct: 257 IVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDM 316
Query: 308 ALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADML----GSAELAE 363
A++ F + + ++D++ D+ + + I TK A + + D E+ E
Sbjct: 317 AIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIE 376
Query: 364 EVNLNGS----GKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKR 419
++++ S KL + S G V + V G++ + + E + + DAL R V++
Sbjct: 377 QLDVTTSEYEKEKLNERLAKLSDGVAV-LKVGGTSDVEVNEKKDRVTDALNATRAAVEE- 434
Query: 420 ALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTE 479
++ GGG + L + + + + +++ T+A+NAG+ V +
Sbjct: 435 GIVLGGGCALLRCIPALDSLT-PANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEK 493
Query: 480 LRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNT 538
+ Q G + G N++E+ ++ P V +AL L V S+L +VV T
Sbjct: 494 I----MQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTAL-LDAAGVASLLTTAEVVVT 547
>gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 62.4 bits (150), Expect = 1e-09
Identities = 94/450 (20%), Positives = 185/450 (41%), Gaps = 43/450 (9%)
Query: 48 IRTSLGPKGMDKMIQDGKGD-VTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGT 106
+ + GP G K + +G G V T+ + +L + V HP ++L + D
Sbjct: 33 VTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCG 92
Query: 107 TSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSR----PVELSDRET 162
I+ +L+++ +L G+ PT + + L I L + PV+ S +
Sbjct: 93 LFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQI 149
Query: 163 LLNSATTSLNSK----VVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTI 218
LL + L SK + + + +S + + A + I + L IV G +
Sbjct: 150 LLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGKSLIVPLKGQRV 209
Query: 219 DDCELVEGLVLTQ-KVSNSGITRVEKA---KIGLIQFCLSAPKTDM-DNQIVVSDYAQMD 273
D ++ G+++ +V + ++K+ K+ L LS +D + +VVS ++
Sbjct: 210 IDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLE 269
Query: 274 RVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDI 333
+ ++ +LNL +Q+ +++L QK ++ +L FLN +I+ I I +
Sbjct: 270 NAVLDQ---LLNLGRQLISDHVDLVLCQK-VIHPSLKQ----FLNMHRIIAIDRIGVTLM 321
Query: 334 EFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRGS 393
E + K GT+P+ + + GS ++V G + ++++
Sbjct: 322 EPLTKMTGTQPIGSLGSICPNSYGS---VKDVCTAKFGSKHFFHLIPNEATICSLLLCNR 378
Query: 394 NKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMES----- 448
N +E + + AL V++ +K+ + GGG E LA + +T + ES
Sbjct: 379 NDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRH--KTHNDPESILKDD 436
Query: 449 --------YCVRAFADAMEVIPSTLAENAG 470
AF A+E + +L + G
Sbjct: 437 ECTQTELQLIAEAFCSALESVVGSLEHDGG 466
>gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 62.4 bits (150), Expect = 1e-09
Identities = 94/450 (20%), Positives = 185/450 (41%), Gaps = 43/450 (9%)
Query: 48 IRTSLGPKGMDKMIQDGKGD-VTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGT 106
+ + GP G K + +G G V T+ + +L + V HP ++L + D
Sbjct: 33 VTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCG 92
Query: 107 TSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSR----PVELSDRET 162
I+ +L+++ +L G+ PT + + L I L + PV+ S +
Sbjct: 93 LFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQI 149
Query: 163 LLNSATTSLNSK----VVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTI 218
LL + L SK + + + +S + + A + I + L IV G +
Sbjct: 150 LLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGKSLIVPLKGQRV 209
Query: 219 DDCELVEGLVLTQ-KVSNSGITRVEKA---KIGLIQFCLSAPKTDM-DNQIVVSDYAQMD 273
D ++ G+++ +V + ++K+ K+ L LS +D + +VVS ++
Sbjct: 210 IDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLE 269
Query: 274 RVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDI 333
+ ++ +LNL +Q+ +++L QK ++ +L FLN +I+ I I +
Sbjct: 270 NAVLDQ---LLNLGRQLISDHVDLVLCQK-VIHPSLKQ----FLNMHRIIAIDRIGVTLM 321
Query: 334 EFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRGS 393
E + K GT+P+ + + GS ++V G + ++++
Sbjct: 322 EPLTKMTGTQPIGSLGSICPNSYGS---VKDVCTAKFGSKHFFHLIPNEATICSLLLCNR 378
Query: 394 NKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMES----- 448
N +E + + AL V++ +K+ + GGG E LA + +T + ES
Sbjct: 379 NDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRH--KTHNDPESILKDD 436
Query: 449 --------YCVRAFADAMEVIPSTLAENAG 470
AF A+E + +L + G
Sbjct: 437 ECTQTELQLIAEAFCSALESVVGSLEHDGG 466
>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
Length = 723
Score = 44.7 bits (104), Expect = 2e-04
Identities = 90/429 (20%), Positives = 169/429 (39%), Gaps = 60/429 (13%)
Query: 37 NISAAKAVADAIRT----SLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLV 92
++ AA VA+ + +GP+G + G+V ++ +G +L+ + + HP ARM+V
Sbjct: 10 SVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIV 69
Query: 93 ELSKAQDIEAGDGTTSVVIIAGSLLDS-------------CTKLLQKGIHPTIISE---- 135
+ + + GDG + +I LL C + G H S
Sbjct: 70 DCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKNCSRWKFI 129
Query: 136 -----SFQKALEKGI--EILTDMSRPVELSDRETLLNSATTSL-------------NSKV 175
+FQ + GI + L+ + S +E L ++ L N K
Sbjct: 130 SQALLTFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRVGRNNHKF 189
Query: 176 VSQY--SSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKV 233
+SQ M+ + + V + V+L V G + D ++ GLVL QK
Sbjct: 190 ISQLMCDYFFKCMTCKSGIGVFELVDDHFVELN----VGVTGLPVSDSRIIAGLVL-QKD 244
Query: 234 SNSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKK- 292
+ ++ ++ + + ++ +++ AQ + + +I+ K I K
Sbjct: 245 FSVYRPADGDMRMVIVTETIQPLFSTSGSEFILNSEAQ----FQTSQFWIMEKTKAIMKH 300
Query: 293 -TGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQF 351
NV L+ S+ + DL ++ I V++ + E++ I + IG P F
Sbjct: 301 LHSQNVKLLISSVKQ---PDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAF 357
Query: 352 TADMLGSAELAEEVN-LNGSGKLLKITGCASPGKTV--TIVVRGSNKLVIEEAERSIHDA 408
+ + + L + L K G S + +IV+ G +IE+ E ++H A
Sbjct: 358 SQCEIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGA 417
Query: 409 LCVIRCLVK 417
L ++R L K
Sbjct: 418 LKMLRQLFK 426
>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
Length = 676
Score = 34.3 bits (77), Expect = 0.30
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 22/133 (16%)
Query: 124 LQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRE----------TLLNSATTSLNS 173
L H ++ QKA + IE+LT S VEL+ +E L ++ T L
Sbjct: 268 LSSANHSLQLASQIQKAPDVAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRE 327
Query: 174 KVVSQYSSLLSPMSV-NAVMKVIDPATATSVDLRDIK----IVKKL-------GGTIDDC 221
SQ S L +S N+ +K ++ D ++K I+K + GT D
Sbjct: 328 NSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQDAA 387
Query: 222 ELVEGLVLTQKVS 234
+ +E L+L + S
Sbjct: 388 KPLEVLLLEKNRS 400
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 33.1 bits (74), Expect = 0.66
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 24/135 (17%)
Query: 124 LQKGIHPTIISESFQKA--LEKGIEILTDMSRPVELSDRE----------TLLNSATTSL 171
L H ++ QKA +E+ IE+LT S VEL+ +E L ++ T L
Sbjct: 257 LSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKL 316
Query: 172 NSKVVSQYSSLLSPMSV-NAVMKVIDPATATSVDLRDIK----IVKKL-------GGTID 219
SQ S L +S N+ +K ++ D ++K I+K + GT D
Sbjct: 317 RENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQD 376
Query: 220 DCELVEGLVLTQKVS 234
+ +E L+L + S
Sbjct: 377 AAKPLEVLLLEKNRS 391
>gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]
Length = 678
Score = 33.1 bits (74), Expect = 0.66
Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 24/135 (17%)
Query: 124 LQKGIHPTIISESFQKA--LEKGIEILTDMSRPVELSDRE----------TLLNSATTSL 171
L H ++ QKA +E+ IE+LT S VEL+ +E L ++ T L
Sbjct: 268 LSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKL 327
Query: 172 NSKVVSQYSSLLSPMSV-NAVMKVIDPATATSVDLRDIK----IVKKL-------GGTID 219
SQ S L +S N+ +K ++ D ++K I+K + GT D
Sbjct: 328 RENSASQISQLEQQLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQD 387
Query: 220 DCELVEGLVLTQKVS 234
+ +E L+L + S
Sbjct: 388 AAKPLEVLLLEKNRS 402
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 465 LAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATE 524
L+ A + P TV + RN TAGI R+ G S +EL P+++ S+ + +
Sbjct: 528 LSPEAAIKPNFTVRDFRNN------TAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSS 581
Query: 525 TVRSILKI 532
T +++
Sbjct: 582 TNTMTIRV 589
>gi|47519562 reticulon 4 isoform E [Homo sapiens]
Length = 986
Score = 32.0 bits (71), Expect = 1.5
Identities = 42/216 (19%), Positives = 87/216 (40%), Gaps = 16/216 (7%)
Query: 62 QDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSL-LDSC 120
QD + D T++ + +++ P + +A + E + T + + + L
Sbjct: 317 QDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQT 376
Query: 121 TKLLQKGIHPTI-ISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQY 179
++++Q+ ++P + SF+++ +L D+ E LNSA S + V+
Sbjct: 377 SEVMQESLYPAAQLCPSFEESEATPSPVLPDIVM-------EAPLNSAVPSAGASVIQPS 429
Query: 180 SSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGIT 239
SS L SVN +P + +KK+ G ++ + E + N+ +
Sbjct: 430 SSPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPENI-------NAALQ 482
Query: 240 RVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRV 275
E I + + K + SDY++M +V
Sbjct: 483 ETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKV 518
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 32.0 bits (71), Expect = 1.5
Identities = 42/216 (19%), Positives = 87/216 (40%), Gaps = 16/216 (7%)
Query: 62 QDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSL-LDSC 120
QD + D T++ + +++ P + +A + E + T + + + L
Sbjct: 523 QDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQT 582
Query: 121 TKLLQKGIHPTI-ISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQY 179
++++Q+ ++P + SF+++ +L D+ E LNSA S + V+
Sbjct: 583 SEVMQESLYPAAQLCPSFEESEATPSPVLPDIVM-------EAPLNSAVPSAGASVIQPS 635
Query: 180 SSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGIT 239
SS L SVN +P + +KK+ G ++ + E + N+ +
Sbjct: 636 SSPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPENI-------NAALQ 688
Query: 240 RVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRV 275
E I + + K + SDY++M +V
Sbjct: 689 ETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKV 724
>gi|33695153 guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide, olfactory type isoform
1 [Homo sapiens]
Length = 458
Score = 31.2 bits (69), Expect = 2.5
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 17/93 (18%)
Query: 7 PRSGATAGA-AGGRGKGAYQDRDKPAQIRFSNISAAK---AVADAIRTSLGPKGMDKMIQ 62
PR G + A A + + R + Q+ AAK AV +A + S +G+D+M++
Sbjct: 54 PRGGEGSPACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVS---RGIDRMLR 110
Query: 63 DGKGDVTITN----------DGATILKQMQVLH 85
D K D+ T+ +TI+KQM++LH
Sbjct: 111 DQKRDLQQTHRLLLLGAGESGKSTIVKQMRILH 143
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 31.2 bits (69), Expect = 2.5
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 12/76 (15%)
Query: 117 LDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELS---DRETLLNSATTSLNS 173
+D C LLQ G PTI + + AL+ L D S L+ ++ LL SA +
Sbjct: 137 IDVCIVLLQHGAEPTIRNTDGRTALD-----LADPSAKAVLTGEYKKDELLESARSGNEE 191
Query: 174 KVVSQYSSLLSPMSVN 189
K++ +LL+P++VN
Sbjct: 192 KMM----ALLTPLNVN 203
>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
Length = 468
Score = 31.2 bits (69), Expect = 2.5
Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 6/71 (8%)
Query: 222 ELVEGLVLTQKVSNSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERA 281
E++ L + +K + + +T EK ++ L Q +T Q+VVS+Y +M + L+EE
Sbjct: 141 EILNLLRVRRKEAQAVLTH-EKERVKLCQ-----EETKTCKQVVVSEYMKMHQFLKEEEQ 194
Query: 282 YILNLVKQIKK 292
L L++Q +K
Sbjct: 195 LQLQLLEQEEK 205
>gi|38348396 hypothetical protein LOC375307 [Homo sapiens]
Length = 387
Score = 30.8 bits (68), Expect = 3.3
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 420 ALIAGGGAPEIELALRLT--EYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTV 477
A+++ G P+ EL + + +Y L GM +YC+ A + + L N+ L +S
Sbjct: 54 AMVSDTGEPQGELTIEVQRGKYQEKL-GMLTYCLFVHASSRGFLDKMLCGNSLLGYLSEK 112
Query: 478 TELRNRHAQ 486
EL +H+Q
Sbjct: 113 LELMEQHSQ 121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,789,199
Number of Sequences: 37866
Number of extensions: 657849
Number of successful extensions: 2104
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2030
Number of HSP's gapped (non-prelim): 45
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.