Search of human proteins with 38424079

Search of human proteins with 38424079

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38424079 short-chain dehydrogenase/reductase 10 isoform c
[Homo sapiens]
         (199 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Ho...   391   e-109
gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Ho...   391   e-109
gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Ho...   358   2e-99
gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Ho...   298   3e-81
gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Ho...   265   2e-71
gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Ho...   171   3e-43
gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]     140   5e-34
gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]      140   5e-34
gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo s...    56   2e-08
gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]          52   3e-07
gi|5031737 dehydrogenase/reductase member 2 isoform 2 [Homo sapi...    51   6e-07
gi|33667109 dehydrogenase/reductase member 2 isoform 1 [Homo sap...    51   6e-07
gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Hom...    51   6e-07
gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo...    50   1e-06
gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo...    48   5e-06
gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [H...    47   8e-06
gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [H...    47   8e-06
gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [H...    47   8e-06
gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo sa...    47   1e-05
gi|22507405 short chain dehydrogenase/reductase family 9C, membe...    47   1e-05
gi|150247226 retinol dehydrogenase 16 [Homo sapiens]                   47   1e-05
gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens]    47   1e-05
gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]     45   3e-05
gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo...    43   2e-04
gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Hom...    43   2e-04
gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Hom...    43   2e-04
gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo...    43   2e-04
gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]         43   2e-04
gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B...    43   2e-04
gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A...    43   2e-04

>gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Homo
           sapiens]
          Length = 199

 Score =  391 bits (1005), Expect = e-109
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 60
           MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS
Sbjct: 1   MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 60

Query: 61  RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 120
           RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM
Sbjct: 61  RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 120

Query: 121 CVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWL 180
           CVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWL
Sbjct: 121 CVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWL 180

Query: 181 PRPRAWFIRQELNVTAAAA 199
           PRPRAWFIRQELNVTAAAA
Sbjct: 181 PRPRAWFIRQELNVTAAAA 199


>gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Homo
           sapiens]
          Length = 286

 Score =  391 bits (1005), Expect = e-109
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 60
           MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS
Sbjct: 88  MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 147

Query: 61  RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 120
           RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM
Sbjct: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 207

Query: 121 CVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWL 180
           CVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWL
Sbjct: 208 CVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWL 267

Query: 181 PRPRAWFIRQELNVTAAAA 199
           PRPRAWFIRQELNVTAAAA
Sbjct: 268 PRPRAWFIRQELNVTAAAA 286


>gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Homo
           sapiens]
          Length = 205

 Score =  358 bits (918), Expect = 2e-99
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 19  GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 78
           GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS
Sbjct: 25  GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 84

Query: 79  LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 138
           LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV
Sbjct: 85  LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 144

Query: 139 TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA 198
           TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA
Sbjct: 145 TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA 204

Query: 199 A 199
           A
Sbjct: 205 A 205


>gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Homo
           sapiens]
          Length = 152

 Score =  298 bits (762), Expect = 3e-81
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 48  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 107
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60

Query: 108 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 167
           ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP
Sbjct: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 120

Query: 168 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 199
           WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA
Sbjct: 121 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 152


>gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Homo
           sapiens]
          Length = 315

 Score =  265 bits (677), Expect = 2e-71
 Identities = 137/139 (98%), Positives = 137/139 (98%)

Query: 1   MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 60
           MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS
Sbjct: 88  MASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 147

Query: 61  RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 120
           RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM
Sbjct: 148 RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITM 207

Query: 121 CVLGLRDRASAAEAVRGVT 139
           CVLGLRDRASAAEAVR  T
Sbjct: 208 CVLGLRDRASAAEAVRSST 226


>gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Homo
           sapiens]
          Length = 181

 Score =  171 bits (434), Expect = 3e-43
 Identities = 90/92 (97%), Positives = 90/92 (97%)

Query: 48  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 107
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60

Query: 108 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 139
           ELDVQDVNVAITMCVLGLRDRASAAEAVR  T
Sbjct: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 92


>gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 292

 Score =  140 bits (354), Expect = 5e-34
 Identities = 79/159 (49%), Positives = 99/159 (62%)

Query: 8   ESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLT 67
           E  V  A   +GGLD L+LNHI               R  M+VNF+SYV LT  ALP L 
Sbjct: 100 EQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLK 159

Query: 68  DSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRD 127
            S GS+VVVSSL G+V       YSA+KFALDGFF S+R+E  V  VNV+IT+CVLGL D
Sbjct: 160 QSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLID 219

Query: 128 RASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFY 166
             +A +AV G+  ++AAP  + AL +I+GGA R   V+Y
Sbjct: 220 TETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYY 258


>gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 292

 Score =  140 bits (354), Expect = 5e-34
 Identities = 79/159 (49%), Positives = 99/159 (62%)

Query: 8   ESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLT 67
           E  V  A   +GGLD L+LNHI               R  M+VNF+SYV LT  ALP L 
Sbjct: 100 EQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLK 159

Query: 68  DSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRD 127
            S GS+VVVSSL G+V       YSA+KFALDGFF S+R+E  V  VNV+IT+CVLGL D
Sbjct: 160 QSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLID 219

Query: 128 RASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFY 166
             +A +AV G+  ++AAP  + AL +I+GGA R   V+Y
Sbjct: 220 TETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYY 258


>gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo
           sapiens]
          Length = 339

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 37/115 (32%), Positives = 56/115 (48%), Gaps = 1/115 (0%)

Query: 8   ESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLT 67
           E+  +  L + G +D LV N      +     S    R L+++N++  V LT   LP + 
Sbjct: 119 EAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMI 178

Query: 68  DSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMC 121
           + K G +V V+S+LG +    S  Y A+K AL GFF  LR EL      +   +C
Sbjct: 179 ERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNIC 233


>gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]
          Length = 311

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 37/103 (35%), Positives = 52/103 (50%), Gaps = 1/103 (0%)

Query: 8   ESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLT 67
           ESV Q      G +D LV N   G        S  A + +   NF   V+L    LP + 
Sbjct: 71  ESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMK 130

Query: 68  DSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRREL 109
             + G +VV+SS++G     F+  Y+A+KFAL+GFF SL  +L
Sbjct: 131 RRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQL 173


>gi|5031737 dehydrogenase/reductase member 2 isoform 2 [Homo
           sapiens]
          Length = 280

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 38/116 (32%), Positives = 61/116 (52%), Gaps = 7/116 (6%)

Query: 5   EAPESVVQFALDKLGGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 60
           E  E +V  AL+  GG+D+LV    +N + G+  GT   S Q    ++ VN  S   L S
Sbjct: 98  EDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGT---SEQIWDKILSVNVKSPALLLS 154

Query: 61  RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
           + LP + + +G++++VSS+    P      Y+ +K AL G   +L  EL  +D+ V
Sbjct: 155 QLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRV 210


>gi|33667109 dehydrogenase/reductase member 2 isoform 1 [Homo
           sapiens]
          Length = 300

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 38/116 (32%), Positives = 61/116 (52%), Gaps = 7/116 (6%)

Query: 5   EAPESVVQFALDKLGGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTS 60
           E  E +V  AL+  GG+D+LV    +N + G+  GT   S Q    ++ VN  S   L S
Sbjct: 98  EDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGT---SEQIWDKILSVNVKSPALLLS 154

Query: 61  RALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
           + LP + + +G++++VSS+    P      Y+ +K AL G   +L  EL  +D+ V
Sbjct: 155 QLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRV 210


>gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Homo
           sapiens]
          Length = 311

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 1/109 (0%)

Query: 10  VVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDS 69
           V +  LD  G +D L+ N            S +  + +M  N+   + LT   LP++   
Sbjct: 109 VAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKALLPNMISR 168

Query: 70  K-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 117
           + G +V+V+++ G+    F T Y+A+K A  GFF  LR E++  DV ++
Sbjct: 169 RTGQIVLVNNIQGKFGIPFRTTYAASKHAALGFFDCLRAEVEEYDVVIS 217


>gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo
           sapiens]
          Length = 325

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 33/106 (31%), Positives = 56/106 (52%), Gaps = 3/106 (2%)

Query: 15  LDKLGGLDYLVLNHIGGAPAGT-RARSPQATRWLMQVNFVSYVQLTSRALPSLTDSK-GS 72
           L   G +D LV N+ G +  GT    +    + +M+ N+   V LT   LPS+   + G 
Sbjct: 130 LQCFGYVDILV-NNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGH 188

Query: 73  LVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 118
           +V +SS+ G++   F + Y+A+K A   FF  LR E++  ++ V +
Sbjct: 189 IVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTV 234


>gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo
           sapiens]
          Length = 270

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 3/93 (3%)

Query: 8   ESVVQFALDKLGGLDYLVLNHIGGAPAGTRAR--SPQATRWLMQVNFVSYVQLTSRALPS 65
           +++V   + + G LD  V+N+ G  P   R    S Q  R L+++N +    LT  ALP 
Sbjct: 70  KTLVSETIRRFGRLD-CVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPY 128

Query: 66  LTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFAL 98
           L  S+G+++ +SSL+G +  + + PY A K A+
Sbjct: 129 LRKSQGNVINISSLVGAIGQAQAVPYVATKGAV 161


>gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
           sapiens]
          Length = 343

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 4/122 (3%)

Query: 1   MASPEAPESVVQFALDKLGGLD---YLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYV 56
           + S E  E VV+     L   +   + ++N+ G +  G     S +  + + +VN    V
Sbjct: 114 VCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTV 173

Query: 57  QLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
           ++T   LP +  +KG +V +SS+LGR+     +PY   KF ++ F   LR E+    V V
Sbjct: 174 RMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKV 233

Query: 117 AI 118
           ++
Sbjct: 234 SV 235


>gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
           sapiens]
          Length = 343

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 4/122 (3%)

Query: 1   MASPEAPESVVQFALDKLGGLD---YLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYV 56
           + S E  E VV+     L   +   + ++N+ G +  G     S +  + + +VN    V
Sbjct: 114 VCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTV 173

Query: 57  QLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
           ++T   LP +  +KG +V +SS+LGR+     +PY   KF ++ F   LR E+    V V
Sbjct: 174 RMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKV 233

Query: 117 AI 118
           ++
Sbjct: 234 SV 235


>gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
           sapiens]
          Length = 343

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 4/122 (3%)

Query: 1   MASPEAPESVVQFALDKLGGLD---YLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYV 56
           + S E  E VV+     L   +   + ++N+ G +  G     S +  + + +VN    V
Sbjct: 114 VCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTV 173

Query: 57  QLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
           ++T   LP +  +KG +V +SS+LGR+     +PY   KF ++ F   LR E+    V V
Sbjct: 174 RMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKV 233

Query: 117 AI 118
           ++
Sbjct: 234 SV 235


>gi|4503817 3-ketodihydrosphingosine reductase precursor [Homo
           sapiens]
          Length = 332

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 42/131 (32%), Positives = 69/131 (52%), Gaps = 5/131 (3%)

Query: 8   ESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQAT-RWLMQVNFVSYVQLTSRALPSL 66
           E+V++ A +KLG +D LV N  G A +G       +T   LM +N++  V  +   + ++
Sbjct: 102 ENVIKQAQEKLGPVDMLV-NCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTM 160

Query: 67  TDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGL 125
            + + G +V VSS  G++     T YSA+KFA+ G   +L  +++V+  NV IT+     
Sbjct: 161 KERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEAL--QMEVKPYNVYITVAYPPD 218

Query: 126 RDRASAAEAVR 136
            D    AE  R
Sbjct: 219 TDTPGFAEENR 229


>gi|22507405 short chain dehydrogenase/reductase family 9C, member 7
           [Homo sapiens]
          Length = 313

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 40/124 (32%), Positives = 59/124 (47%), Gaps = 18/124 (14%)

Query: 5   EAPESVVQFALDKLG--GLDYLVLNHIGGAPAGTRARSPQATRWL--------MQVNFVS 54
           E+ ++  Q+  DK+G  GL  LV N   G P+G          WL        + VN V 
Sbjct: 84  ESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPN-------EWLTKDDFVKVINVNLVG 136

Query: 55  YVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDV 114
            +++T   LP +  ++G +V +SS  GRV       Y  +KF ++ F  S+RREL    V
Sbjct: 137 LIEVTLHMLPMVKRARGRVVNMSSSGGRVAV-IGGGYCVSKFGVEAFSDSIRRELYYFGV 195

Query: 115 NVAI 118
            V I
Sbjct: 196 KVCI 199


>gi|150247226 retinol dehydrogenase 16 [Homo sapiens]
          Length = 317

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 26/72 (36%), Positives = 43/72 (59%), Gaps = 1/72 (1%)

Query: 47  LMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 106
           ++ VN +  + +T   LP +  ++G +V VSS++GRV + F   Y  +K+ ++ F  SLR
Sbjct: 133 ILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRV-SLFGGGYCISKYGVEAFSDSLR 191

Query: 107 RELDVQDVNVAI 118
           REL    V VA+
Sbjct: 192 RELSYFGVKVAM 203


>gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens]
          Length = 317

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 25/72 (34%), Positives = 43/72 (59%), Gaps = 1/72 (1%)

Query: 47  LMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 106
           +++VN +  +Q+T   LP +  ++G +V VSS+LGRV   F   Y  +K+ ++ F   LR
Sbjct: 133 MLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRV-AFFVGGYCVSKYGVEAFSDILR 191

Query: 107 RELDVQDVNVAI 118
           RE+    V ++I
Sbjct: 192 REIQHFGVKISI 203


>gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]
          Length = 387

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 2/97 (2%)

Query: 23  YLVLNHIG--GAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLL 80
           + V+N+ G  G P           +  M VNF   V++T   LP L  SKG LV VSS+ 
Sbjct: 162 WAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMG 221

Query: 81  GRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 117
           G  P      Y ++K A+  F   +R EL    + VA
Sbjct: 222 GGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVA 258


>gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 34/120 (28%), Positives = 64/120 (53%), Gaps = 4/120 (3%)

Query: 1   MASPEAPESVVQFALDKLG--GLDYLVLNH-IGGAPAGTRARSPQATRWLMQVNFVSYVQ 57
           +  PE  +   Q+  +++G  GL  L+ N  + G  A T   + +  R  ++VN    + 
Sbjct: 84  VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143

Query: 58  LTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 117
           +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR++    V+V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202


>gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 34/120 (28%), Positives = 64/120 (53%), Gaps = 4/120 (3%)

Query: 1   MASPEAPESVVQFALDKLG--GLDYLVLNH-IGGAPAGTRARSPQATRWLMQVNFVSYVQ 57
           +  PE  +   Q+  +++G  GL  L+ N  + G  A T   + +  R  ++VN    + 
Sbjct: 84  VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143

Query: 58  LTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 117
           +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR++    V+V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202


>gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 34/120 (28%), Positives = 64/120 (53%), Gaps = 4/120 (3%)

Query: 1   MASPEAPESVVQFALDKLG--GLDYLVLNH-IGGAPAGTRARSPQATRWLMQVNFVSYVQ 57
           +  PE  +   Q+  +++G  GL  L+ N  + G  A T   + +  R  ++VN    + 
Sbjct: 84  VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143

Query: 58  LTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 117
           +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR++    V+V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202


>gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 34/120 (28%), Positives = 64/120 (53%), Gaps = 4/120 (3%)

Query: 1   MASPEAPESVVQFALDKLG--GLDYLVLNH-IGGAPAGTRARSPQATRWLMQVNFVSYVQ 57
           +  PE  +   Q+  +++G  GL  L+ N  + G  A T   + +  R  ++VN    + 
Sbjct: 84  VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143

Query: 58  LTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 117
           +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR++    V+V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202


>gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]
          Length = 300

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 49  QVNFVSYVQLTSRALPSLT-DSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 107
           +VN +++   T   LP++T ++ G +V V+S  G V   F   Y ++KFA  GF  +L  
Sbjct: 142 EVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTD 201

Query: 108 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAAL-AVIRGGATRAAGVFY 166
           EL    +    T C+    +  +        T +     P+  +  ++ G  T    +F 
Sbjct: 202 ELAALQITGVKTTCL--CPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFI 259

Query: 167 PWRFRLLCLLRRWLPRPRAWFIRQELNV 194
           P     L  L R LP      ++Q+++V
Sbjct: 260 PSSIAFLTTLERILPERFLAVLKQKISV 287


>gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B
           [Homo sapiens]
          Length = 264

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 39/174 (22%), Positives = 73/174 (41%), Gaps = 5/174 (2%)

Query: 24  LVLNHIGGA-PAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLG 81
           +V+N+ G   PA   +   +      +VN + +  +T   LPS+ + + G +V V+S+ G
Sbjct: 80  IVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCG 139

Query: 82  RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRV 141
                +  PY ++KFA  GF   L  EL         T C+  +    +        TR+
Sbjct: 140 HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV--FVNTGFTKNPSTRL 197

Query: 142 -KAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNV 194
                  +   ++I G  T    +F P    +   L+++LP   +  + +  N+
Sbjct: 198 WPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNI 251


>gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A
           [Homo sapiens]
          Length = 300

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 39/174 (22%), Positives = 73/174 (41%), Gaps = 5/174 (2%)

Query: 24  LVLNHIGGA-PAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLG 81
           +V+N+ G   PA   +   +      +VN + +  +T   LPS+ + + G +V V+S+ G
Sbjct: 116 IVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCG 175

Query: 82  RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRV 141
                +  PY ++KFA  GF   L  EL         T C+  +    +        TR+
Sbjct: 176 HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV--FVNTGFTKNPSTRL 233

Query: 142 -KAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNV 194
                  +   ++I G  T    +F P    +   L+++LP   +  + +  N+
Sbjct: 234 WPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNI 287


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,291,543
Number of Sequences: 37866
Number of extensions: 288497
Number of successful extensions: 1027
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 985
Number of HSP's gapped (non-prelim): 55
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.