BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38373671 SEC24-related protein C [Homo sapiens] (1094 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|38373671 SEC24-related protein C [Homo sapiens] 2227 0.0 gi|38373669 SEC24-related protein C [Homo sapiens] 2227 0.0 gi|190343021 Sec24-related protein D [Homo sapiens] 1158 0.0 gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sap... 426 e-119 gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 418 e-116 gi|116174780 SEC24 related gene family, member A [Homo sapiens] 395 e-109 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 93 2e-18 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 81 5e-15 gi|163965366 nascent polypeptide-associated complex alpha subuni... 81 5e-15 gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 81 5e-15 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 80 1e-14 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 75 3e-13 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 75 3e-13 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 4e-13 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 74 6e-13 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 74 6e-13 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 74 6e-13 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 74 6e-13 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 70 8e-12 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 70 8e-12 gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 70 8e-12 gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 69 2e-11 gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 69 2e-11 gi|55750053 atrophin-1 [Homo sapiens] 69 2e-11 gi|55750041 atrophin-1 [Homo sapiens] 69 2e-11 gi|150170670 piccolo isoform 2 [Homo sapiens] 69 3e-11 gi|150378539 piccolo isoform 1 [Homo sapiens] 69 3e-11 gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho... 68 5e-11 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 67 7e-11 gi|47132519 Ras association and pleckstrin homology domains 1 is... 67 1e-10 >gi|38373671 SEC24-related protein C [Homo sapiens] Length = 1094 Score = 2227 bits (5770), Expect = 0.0 Identities = 1094/1094 (100%), Positives = 1094/1094 (100%) Query: 1 MNVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMS 60 MNVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMS Sbjct: 1 MNVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMS 60 Query: 61 RAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQ 120 RAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQ Sbjct: 61 RAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQ 120 Query: 121 PPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYG 180 PPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYG Sbjct: 121 PPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYG 180 Query: 181 SYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPS 240 SYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPS Sbjct: 181 SYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPS 240 Query: 241 VSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPY 300 VSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPY Sbjct: 241 VSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPY 300 Query: 301 PAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTN 360 PAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTN Sbjct: 301 PAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTN 360 Query: 361 FLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGES 420 FLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGES Sbjct: 361 FLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGES 420 Query: 421 GPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELS 480 GPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELS Sbjct: 421 GPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELS 480 Query: 481 LGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGA 540 LGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGA Sbjct: 481 LGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGA 540 Query: 541 EESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITS 600 EESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITS Sbjct: 541 EESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITS 600 Query: 601 LLDQIPEMFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDD 660 LLDQIPEMFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDD Sbjct: 601 LLDQIPEMFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDD 660 Query: 661 RKLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSV 720 RKLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSV Sbjct: 661 RKLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSV 720 Query: 721 YKYASFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVEL 780 YKYASFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVEL Sbjct: 721 YKYASFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVEL 780 Query: 781 AGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYR 840 AGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYR Sbjct: 781 AGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYR 840 Query: 841 NCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILPEC 900 NCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILPEC Sbjct: 841 NCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILPEC 900 Query: 901 MKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVE 960 MKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVE Sbjct: 901 MKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVE 960 Query: 961 STTEPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSGLSV 1020 STTEPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSGLSV Sbjct: 961 STTEPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSGLSV 1020 Query: 1021 LPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGASYVD 1080 LPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGASYVD Sbjct: 1021 LPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGASYVD 1080 Query: 1081 FLCHMHKEIRQLLS 1094 FLCHMHKEIRQLLS Sbjct: 1081 FLCHMHKEIRQLLS 1094 >gi|38373669 SEC24-related protein C [Homo sapiens] Length = 1094 Score = 2227 bits (5770), Expect = 0.0 Identities = 1094/1094 (100%), Positives = 1094/1094 (100%) Query: 1 MNVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMS 60 MNVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMS Sbjct: 1 MNVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMS 60 Query: 61 RAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQ 120 RAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQ Sbjct: 61 RAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQ 120 Query: 121 PPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYG 180 PPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYG Sbjct: 121 PPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYG 180 Query: 181 SYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPS 240 SYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPS Sbjct: 181 SYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPS 240 Query: 241 VSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPY 300 VSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPY Sbjct: 241 VSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPY 300 Query: 301 PAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTN 360 PAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTN Sbjct: 301 PAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTN 360 Query: 361 FLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGES 420 FLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGES Sbjct: 361 FLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGES 420 Query: 421 GPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELS 480 GPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELS Sbjct: 421 GPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELS 480 Query: 481 LGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGA 540 LGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGA Sbjct: 481 LGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGA 540 Query: 541 EESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITS 600 EESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITS Sbjct: 541 EESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITS 600 Query: 601 LLDQIPEMFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDD 660 LLDQIPEMFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDD Sbjct: 601 LLDQIPEMFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDD 660 Query: 661 RKLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSV 720 RKLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSV Sbjct: 661 RKLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSV 720 Query: 721 YKYASFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVEL 780 YKYASFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVEL Sbjct: 721 YKYASFQVENDQERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVEL 780 Query: 781 AGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYR 840 AGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYR Sbjct: 781 AGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYR 840 Query: 841 NCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILPEC 900 NCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILPEC Sbjct: 841 NCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILPEC 900 Query: 901 MKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVE 960 MKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVE Sbjct: 901 MKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVE 960 Query: 961 STTEPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSGLSV 1020 STTEPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSGLSV Sbjct: 961 STTEPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSGLSV 1020 Query: 1021 LPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGASYVD 1080 LPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGASYVD Sbjct: 1021 LPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGASYVD 1080 Query: 1081 FLCHMHKEIRQLLS 1094 FLCHMHKEIRQLLS Sbjct: 1081 FLCHMHKEIRQLLS 1094 >gi|190343021 Sec24-related protein D [Homo sapiens] Length = 1032 Score = 1158 bits (2995), Expect = 0.0 Identities = 599/1061 (56%), Positives = 766/1061 (72%), Gaps = 50/1061 (4%) Query: 44 YNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQ--APCGQAAYGQFGQGDVQNGPSSTVQM 101 Y+ P PG +PP PS A P + P G A +G + GP Sbjct: 12 YSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATAT----RGMLPPGPPP---- 63 Query: 102 QRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFG 161 PG FG A PP P GPPP + ++ + AP PS+ + Sbjct: 64 ---PGPHQFGQNGAHATGHPPQRFP-GPPPVN----------NVASSHAPYQPSAQSSYP 109 Query: 162 PPTSLASAS--GSFPNSGLYGSYPQGQAPPLSQAQGHPG------IQTPQRSAPSQASSF 213 P S +S + GS ++ SY G APP +QG PG +QTP R P Q S Sbjct: 110 GPISTSSVTQLGSQLSAMQINSYGSGMAPP---SQGPPGPLSATSLQTPPR--PPQPSIL 164 Query: 214 TPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSP 273 P + P P+ PG S + +P+ +S PP PP Q P PLP Sbjct: 165 QPGSQVLPPPPTTLNG--PGASPLPLPMYRPDGLSGPP---PPNAQYQPP--PLPGQ--T 215 Query: 274 QQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVI 333 GY PQQ S G Q +Y G +P P GPPQP K+LDPD+IPSPIQVI Sbjct: 216 LGAGYPPQQANSGPQMAGAQLSYPGGFPGGPA--QMAGPPQP--QKKLDPDSIPSPIQVI 271 Query: 334 EDDRNNRGTEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQV 393 E+DR +RG + + T RGQ+PPLVTT+ +++DQGNASPR+IRCT+Y PCTSDMAKQAQ+ Sbjct: 272 ENDRASRGGQVYATNTRGQIPPLVTTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQI 331 Query: 394 PLAAVIKPLARLPPEEASPYVVDHGESGPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCI 453 PLAAVIKP A +P E+ Y+V+HGESGP+RCNRCKAYMCPFMQFIEGGRR+QC FC+C+ Sbjct: 332 PLAAVIKPFATIPSNESPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCNCV 391 Query: 454 NDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYN 513 NDVPP YFQHLDH G+R+D Y++PELSLGSYE++AT+DYC+ +K P+PPAFIFMIDVSY+ Sbjct: 392 NDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYS 451 Query: 514 AIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVV 573 I+ GLV+L+CEELK++L+ +P+E E SAIRVGF+TYNKVLHF+NVKS+LAQPQMMVV Sbjct: 452 NIKNGLVKLICEELKTMLEKIPKEEQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVV 511 Query: 574 SDVADMFVPLLDGFLVNVNESRAVITSLLDQIPEMFADTRETETVFVPVIQAGMEALKAA 633 +DV ++FVPLLDGFLVN ES++VI +LLDQIP+MFAD+ E ETVF PVIQAGMEALKAA Sbjct: 512 TDVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPDMFADSNENETVFAPVIQAGMEALKAA 571 Query: 634 ECAGKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGAYQTLAKECVAQGCC 693 +C GKLF+FH+SLP AEAPGKLKNRDD+KL+NTDKEK LFQPQT Y +LAK+CVA GC Sbjct: 572 DCPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTNVYDSLAKDCVAHGCS 631 Query: 694 VDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQERFLSDLRRDVQKVVGFDAVM 753 V LFLFP+QYVDVA+L +VPQLTGG++YKY +FQ+ D+++FL+DLR D++K +GFDA+M Sbjct: 632 VTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQFLNDLRNDIEKKIGFDAIM 691 Query: 754 RVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEESGALLQCALLY 813 RVRTSTG RA DFFG M+NTTDVE+A +D DK VTVEFKHDD+L+E+SGAL+QCA+LY Sbjct: 692 RVRTSTGFRATDFFGGILMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLY 751 Query: 814 TSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRGVLNSPVKAVRDTLIT 873 T+ +GQRRLRIHNL LNC +QLADLY++CETD LIN+ AK A++ VL+ P+K +R+ L+ Sbjct: 752 TTISGQRRLRIHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVN 811 Query: 874 QCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQ 933 Q A +LACYRKNCASPS+A QLILP+ MK+LPVY+NC+LK+ VL E++TD+RAY RQ Sbjct: 812 QTAHMLACYRKNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQ 871 Query: 934 LVTSMDVTETNVFFYPRLLPLTKSPVESTTEPPAVRASEERLSNGDIYLLENGLNLFLWV 993 LV +M V ++ +FFYP+LLP+ V+ST P AVR SE RLS I+LL NGL++FLW+ Sbjct: 872 LVMTMGVADSQLFFYPQLLPIHTLDVKSTMLPAAVRCSESRLSEEGIFLLANGLHMFLWL 931 Query: 994 GASVQQGVVQSLFSVSSFSQITSGLSVLPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVK 1053 G S ++Q +F+V SF+ I + +++LP + NP S+++R ++ ++ +R MKLT+VK Sbjct: 932 GVSSPPELIQGIFNVPSFAHINTDMTLLPEVGNPYSQQLRMIMGIIQQKRPYSMKLTIVK 991 Query: 1054 QEDKMEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQLLS 1094 Q ++ EM+F+ FLVEDK L GG+SYVDFLC +HKEI QLL+ Sbjct: 992 QREQPEMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN 1032 Score = 43.9 bits (102), Expect = 8e-04 Identities = 41/149 (27%), Positives = 53/149 (35%), Gaps = 18/149 (12%) Query: 199 IQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGT 258 + TP S P +PP G PS T GP + PP PPG Sbjct: 7 VATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGP 66 Query: 259 QMTGPLGPLPPMHSPQQ-PGYQPQQN--GSFGPAR-GPQSNYGGPYPAAP---------- 304 G G H PQ+ PG P N S P + QS+Y GP + Sbjct: 67 HQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSA 126 Query: 305 ----TFGSQPGPPQPLPPKRLDPDAIPSP 329 ++GS PP PP L ++ +P Sbjct: 127 MQINSYGSGMAPPSQGPPGPLSATSLQTP 155 Score = 43.9 bits (102), Expect = 8e-04 Identities = 69/275 (25%), Positives = 84/275 (30%), Gaps = 78/275 (28%) Query: 2 NVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSR 61 NV S P P Q YPG +S Q GS A+ +Y G Sbjct: 92 NVASSHAPYQPSAQSS--YPGPISTSSVTQLGSQLSAMQINSY-------------GSGM 136 Query: 62 APPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQP 121 APPS G P GP S +Q P QP Sbjct: 137 APPSQGPP------------------------GPLSATSLQTPPRPP-----------QP 161 Query: 122 PVLQP----YGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSG 177 +LQP PPPT+ L+G S P GL PP + P Sbjct: 162 SILQPGSQVLPPPPTT------LNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQT 215 Query: 178 LYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPS-MTGPLLPGQSF 236 L YP QA S P A + G P P+ M GP P + Sbjct: 216 LGAGYPPQQA----------------NSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKL 259 Query: 237 GGPSVSQPNHVSSPPQALPPG-TQMTGPLGPLPPM 270 S+ P V +A G T G +PP+ Sbjct: 260 DPDSIPSPIQVIENDRASRGGQVYATNTRGQIPPL 294 >gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sapiens] Length = 1268 Score = 426 bits (1096), Expect = e-119 Identities = 324/1099 (29%), Positives = 508/1099 (46%), Gaps = 77/1099 (7%) Query: 37 PAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPS 96 P++P G G + Q P + SG A + +P Q Q +G S Sbjct: 199 PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYS 258 Query: 97 S-TVQMQRLPGSQP-----FGSPLAPVGNQP----------PVLQPYGPPPTSAQVATQL 140 + T LP +Q LA N P PV+Q PP +S V+T L Sbjct: 259 TLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVL 318 Query: 141 SGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGL-YGSYPQGQAP----PLSQAQG 195 SG S + PP++ P TS+ S G+ YG Y QA PLS Sbjct: 319 SGSSGSSSTR-TPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSD 377 Query: 196 HPGIQTPQRSAPSQASSFTPPASGGPR-LPSMTGPLLPGQSFGGPSVSQPNHVSSP-PQA 253 + A +SS T AS P ++ G P S P+ P P + Sbjct: 378 DEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPAS 437 Query: 254 LPPGTQMTGPLGPLPP-MHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGP 312 P P+ P P M P GY Q G + A P + G P+ P + Sbjct: 438 APAPASAPAPVVPQPSKMAKPFGYGYPTLQPG-YQNATAPLIS--GVQPSNPVYSGFQQY 494 Query: 313 PQPLPPKR--------LDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTNFLVK 364 PQ P L + P P + + +T V VP L N +K Sbjct: 495 PQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNL---NADLK 551 Query: 365 DQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKP---LARLPPEEASPYVVDHGESG 421 N SP RCT NIP T + +A++PL ++ P L +LP ++ V Sbjct: 552 KL-NCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIV------- 603 Query: 422 PLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSL 481 RC C+ Y+ PF+ FI+ RR++C C +NDVP + F + T + + RPE+ Sbjct: 604 --RCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEE-FMYNPLTRSYGEPHKRPEVQN 659 Query: 482 GSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGAE 541 + EF+A+ DY P P ++F++DVS+NA+ G + +LC+ L LD LP + Sbjct: 660 STVEFIASSDYMLRP--PQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGD---- 713 Query: 542 ESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITSL 601 S R+GF+T++ +HFYN++ L+QPQM++VSD+ D+F+P D LVN+ ES+ +I L Sbjct: 714 -SRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDL 772 Query: 602 LDQIPEMFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDDR 661 L+ +P MF +TRET + P +QA + + + G++ +F T LP A G L++R+D Sbjct: 773 LNALPNMFTNTRETHSALGPALQAAFKLM--SPTGGRVSVFQTQLPSLGA-GLLQSREDP 829 Query: 662 KLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVY 721 ++ K P T Y+ LA +C Q VDLFL +QY D+A+L+ + + + G +Y Sbjct: 830 NQRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIY 889 Query: 722 KYASFQVEND---QERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDV 778 Y SF ++ E+ DL+R + + +GF+AVMR+R + G+ F G F++ +T + Sbjct: 890 YYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLL 949 Query: 779 ELAGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADL 838 LA ++ D V+ ++ L + S Q ALLYTS G+RR+R+H L L + LAD+ Sbjct: 950 SLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADV 1009 Query: 839 YRNCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILP 898 Y + I +A A ++S + RD L+ L+ Y ++ + L+ P Sbjct: 1010 YAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSA-LMAP 1068 Query: 899 ECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSP 958 +KL P+Y+ +LK + G DDR Y + S + +P L + + Sbjct: 1069 SSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLT 1128 Query: 959 VESTT--------EPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSS 1010 E +PP + S E+L+ +L++ G ++WVG ++ + ++ Sbjct: 1129 DEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTN 1188 Query: 1011 FSQITSGLSVLPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDK 1070 F+ I ++ LP LD S++ R I LR R L +VK E + F L+ED+ Sbjct: 1189 FASIPQKMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDR 1248 Query: 1071 SLSGGASYVDFLCHMHKEI 1089 + SY +FL H+ ++I Sbjct: 1249 T-EAAFSYYEFLLHVQQQI 1266 Score = 38.5 bits (88), Expect = 0.035 Identities = 78/289 (26%), Positives = 95/289 (32%), Gaps = 66/289 (22%) Query: 12 PFGQPQPIYPGYHQSSYGGQ--SGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG-- 67 P G P +GG SG+ APA P GA GP P Q P Q + P G Sbjct: 4 PAGSSHPAASARIPPKFGGAAVSGAAAPAGP-GA--GPAPHQQNGPAQNQMQVPSGYGLH 60 Query: 68 -----APPASTAQAP-----------CGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFG 111 AP +Q P CG Y QN +TV Q PG+Q Sbjct: 61 HQNYIAPSGHYSQGPGKMTSLPLDTQCGD-YYSALYTVPTQNVTPNTVNQQ--PGAQQ-- 115 Query: 112 SPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASG 171 L GPP A + G + A +S L TS + Sbjct: 116 ------------LYSRGPP------APHIVGSTLGSFQGAASSASHL----HTSASQPYS 153 Query: 172 SFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLL 231 SF N Y S A +QG P T A S S+ P+ P LP+ Sbjct: 154 SFVNH--YNSPAMYSASSSVASQGFP--STCGHYAMSTVSNAAYPSVSYPSLPA------ 203 Query: 232 PGQSFGGPSVSQPNHVSSPPQALPPGTQMT-----GPLGPLPPMHSPQQ 275 G ++G SQ P + Q T PL PLP QQ Sbjct: 204 -GDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQ 251 >gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sapiens] Length = 1233 Score = 418 bits (1075), Expect = e-116 Identities = 319/1093 (29%), Positives = 509/1093 (46%), Gaps = 100/1093 (9%) Query: 37 PAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPS 96 P++P G G + Q P + SG A + +P Q Q +G S Sbjct: 199 PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYS 258 Query: 97 S-TVQMQRLPGSQP-----FGSPLAPVGNQP----------PVLQPYGPPPTSAQVATQL 140 + T LP +Q LA N P PV+Q PP +S V+T L Sbjct: 259 TLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVL 318 Query: 141 SGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQ------ 194 SG S + PP++ P TS+ S G+ S A P+ + Sbjct: 319 SGSSGSSSTR-TPPTANHPVEPVTSVTQPSELLQQKGVDSSSTTSSASPMPNSYDALEGG 377 Query: 195 GHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQAL 254 +P + + S+P+ + P + P S P++P S +++P P L Sbjct: 378 SYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPS----KMAKPFGYGYP--TL 431 Query: 255 PPGTQ-MTGPLGPLPPMHSPQQPGYQ--PQQNGSFGPARGPQSNYGGPYPAAPTFGSQPG 311 PG Q T PL +P G+Q PQQ + S+ GG Q Sbjct: 432 QPGYQNATAPLISGVQPSNPVYSGFQQYPQQ---YPGVNQLSSSIGG-------LSLQSS 481 Query: 312 P-PQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTNFLVKDQGNAS 370 P P+ L P L + P+ T V VP L N +K N S Sbjct: 482 PQPESLRPVNLTQERNILPM----------------TPVWAPVPNL---NADLKKL-NCS 521 Query: 371 PRYIRCTSYNIPCTSDMAKQAQVPLAAVIKP---LARLPPEEASPYVVDHGESGPLRCNR 427 P RCT NIP T + +A++PL ++ P L +LP ++ V RC Sbjct: 522 PDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIV---------RCRS 572 Query: 428 CKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFL 487 C+ Y+ PF+ FI+ RR++C C +NDVP + F + T + + RPE+ + EF+ Sbjct: 573 CRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEE-FMYNPLTRSYGEPHKRPEVQNSTVEFI 630 Query: 488 ATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGAEESAIRV 547 A+ DY P P ++F++DVS+NA+ G + +LC+ L LD LP + S R+ Sbjct: 631 ASSDYMLRP--PQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGD-----SRTRI 683 Query: 548 GFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITSLLDQIPE 607 GF+T++ +HFYN++ L+QPQM++VSD+ D+F+P D LVN+ ES+ +I LL+ +P Sbjct: 684 GFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPN 743 Query: 608 MFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDDRKLINTD 667 MF +TRET + P +QA + + + G++ +F T LP A G L++R+D ++ Sbjct: 744 MFTNTRETHSALGPALQAAFKLM--SPTGGRVSVFQTQLPSLGA-GLLQSREDPNQRSST 800 Query: 668 KEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQ 727 K P T Y+ LA +C Q VDLFL +QY D+A+L+ + + + G +Y Y SF Sbjct: 801 KVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFH 860 Query: 728 VEND---QERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLD 784 ++ E+ DL+R + + +GF+AVMR+R + G+ F G F++ +T + LA ++ Sbjct: 861 YTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANIN 920 Query: 785 GDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADLYRNCET 844 D V+ ++ L + S Q ALLYTS G+RR+R+H L L + LAD+Y + Sbjct: 921 PDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDV 980 Query: 845 DTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILPECMKLL 904 I +A A ++S + RD L+ L+ Y ++ + L+ P +KL Sbjct: 981 QAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSA-LMAPSSLKLF 1039 Query: 905 PVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSPVESTT- 963 P+Y+ +LK + G DDR Y + S + +P L + + E Sbjct: 1040 PLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVH 1099 Query: 964 -------EPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITS 1016 +PP + S E+L+ +L++ G ++WVG ++ + ++F+ I Sbjct: 1100 VNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQ 1159 Query: 1017 GLSVLPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGA 1076 ++ LP LD S++ R I LR R L +VK E + F L+ED++ Sbjct: 1160 KMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRT-EAAF 1218 Query: 1077 SYVDFLCHMHKEI 1089 SY +FL H+ ++I Sbjct: 1219 SYYEFLLHVQQQI 1231 Score = 41.2 bits (95), Expect = 0.005 Identities = 99/413 (23%), Positives = 140/413 (33%), Gaps = 105/413 (25%) Query: 12 PFGQPQPIYPGYHQSSYGGQ--SGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG-- 67 P G P +GG SG+ APA P GA GP P Q P Q + P G Sbjct: 4 PAGSSHPAASARIPPKFGGAAVSGAAAPAGP-GA--GPAPHQQNGPAQNQMQVPSGYGLH 60 Query: 68 -----APPASTAQAP-----------CGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFG 111 AP +Q P CG Y QN +TV Q PG+Q Sbjct: 61 HQNYIAPSGHYSQGPGKMTSLPLDTQCGD-YYSALYTVPTQNVTPNTVNQQ--PGAQQLY 117 Query: 112 S--PLAP--VGNQPPVLQPYGPPPTSAQVATQLSG--------------MQISGAVAPAP 153 S P AP VG+ Q G +++ + T S S +VA Sbjct: 118 SRGPPAPHIVGSTLGSFQ--GAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQG 175 Query: 154 PSSGLGFGPPTSLASA---SGSFPNSGLYGSYPQ-------------------GQAPPLS 191 S G +++++A S S+P+ +Y Q GQ +S Sbjct: 176 FPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAIS 235 Query: 192 QAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQ------SFGGPSVSQPN 245 P + + Q S ++ P LPS L+ + P+++ + Sbjct: 236 HPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVAD 295 Query: 246 HVS-------SPPQALP-PGTQMTGPLG------------PLPPMHSPQQPGYQPQQNG- 284 +S PP++ P T ++G G P+ P+ S QP QQ G Sbjct: 296 SLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGV 355 Query: 285 ---SFGPARGPQSN-----YGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSP 329 S + P N GG YP S P P P DP + P+P Sbjct: 356 DSSSTTSSASPMPNSYDALEGGSYP--DMLSSSASSPAPDPAPEPDPASAPAP 406 >gi|116174780 SEC24 related gene family, member A [Homo sapiens] Length = 1093 Score = 395 bits (1015), Expect = e-109 Identities = 312/1130 (27%), Positives = 510/1130 (45%), Gaps = 144/1130 (12%) Query: 63 PPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQ------RLPGSQPFGSP--- 113 P S GAP + AQ A+ + G VQN S+ + +LPGS P P Sbjct: 7 PASGGAPASLQAQNGAALASGSPYTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAKT 66 Query: 114 LAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGP------PTSLA 167 L PV Q YG S Q + VA P + L GP P S Sbjct: 67 LNPVSGQ----SNYGGSQGSGQTLNR-------PPVASNPVTPSLHSGPAPRMPLPASQN 115 Query: 168 SASGSFPNSGLYGSYPQGQAPP-LSQAQGHPGIQTPQRSAPSQASSFTPPASG------- 219 A+ P+S P+ PP L+ +P + P +S P SG Sbjct: 116 PATTPMPSSSFL---PEANLPPPLNWQYNYPSTASQTNHCPRASSQ--PTVSGNTSLTTN 170 Query: 220 ------------------GPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPP-QALPPGTQM 260 GP +P + P LP G P PP +AL P T Sbjct: 171 HQYVSSGYPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGPPPVRALTPLTSS 230 Query: 261 TGPLGPLPPMHSP--QQPGYQPQQNGSF------------GPARGPQSNYGGP------- 299 + P P +S Q+ NGS G PQ P Sbjct: 231 YRDV-PQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSVG 289 Query: 300 --YPAAPTFGSQPGPPQP--LPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPP 355 YP+ P PP +PP L+ + P N+ T ++G+ Q Sbjct: 290 YSYPSLPPGYQNTTPPGATGVPPSSLNYPSGPQAFTQTPLGANHLTTS--MSGLSLQPEG 347 Query: 356 LVTTNFLVK--------------------DQGNASPRYIRCTSYNIPCTSDMAKQAQVPL 395 L N L + + N +P RCT +IP T + +A++PL Sbjct: 348 LRVVNLLQERNMLPSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQTQALLNKAKLPL 407 Query: 396 AAVIKP---LARLPPEEASPYVVDHGESGPLRCNRCKAYMCPFMQFIEGGRRFQCCFCSC 452 ++ P L +LP +S V RC C+ Y+ PF+ F++ RR++C C Sbjct: 408 GLLLHPFKDLVQLPVVTSSTIV---------RCRSCRTYINPFVSFLDQ-RRWKCNLCYR 457 Query: 453 INDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVDYCKNNKFPSPPAFIFMIDVSY 512 +NDVP ++ + T + + RPE+ + EF+A +Y P PP ++F+ DVS+ Sbjct: 458 VNDVPEEFLYN-PLTRVYGEPHRRPEVQNATIEFMAPSEYMLRP--PQPPVYLFVFDVSH 514 Query: 513 NAIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMV 572 NA+ TG + +C+ L LD LP + ++GF+T++ +HFY ++ SL+QPQM++ Sbjct: 515 NAVETGYLNSVCQSLLDNLDLLPGN-----TRTKIGFITFDSTIHFYGLQESLSQPQMLI 569 Query: 573 VSDVADMFVPLLDGFLVNVNESRAVITSLLDQIPEMFADTRETETVFVPVIQAGMEALKA 632 VSD+ D+F+P+ + LVN+NES+ ++ LL +P+MF T ET++ P +QA + + Sbjct: 570 VSDIEDVFIPMPENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLM-- 627 Query: 633 AECAGKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGAYQTLAKECVAQGC 692 + G++ +F T LP G LK R++ ++ K+ + P T Y+ LA +C Q Sbjct: 628 SPTGGRMSVFQTQLPTL-GVGALKPREEPNHRSSAKDIHM-TPSTDFYKKLALDCSGQQV 685 Query: 693 CVDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQ---ERFLSDLRRDVQKVVGF 749 VDLFL QY D+A+L + + + GSVY Y S+ +++ ++ +L+R + + +GF Sbjct: 686 AVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGF 745 Query: 750 DAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLDGDKTVTVEFKHDDRLNEESGALLQC 809 +AVMR+R + G+ F G F++ +T + L ++ D V+ ++ L + Q Sbjct: 746 EAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQS 805 Query: 810 ALLYTSCAGQRRLRIHNLALNCCTQLADLYRNCETDTLINYMAKFAYRGVLNSPVKAVRD 869 ALLYTS G+RR+R+H L L + L D++ + + +A A + + + RD Sbjct: 806 ALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLSDARD 865 Query: 870 TLITQCAQILACYRKNCASPSSAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRA 929 L+ L+ YR + S G L++P ++L P+++ +LK Q G D+R Sbjct: 866 ALVNAVIDSLSAYRSSVLSNQQPG-LMVPFSLRLFPLFVLALLKQKSFQTGTNARLDERI 924 Query: 930 YVRQLVTSMDVTETNVFFYPRLLPLTKSPVE--------STTEPPAVRASEERLSNGDIY 981 + V + + + +P L + E + +PP ++ S E+LS + Sbjct: 925 FAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALNISDRTIPQPPILQLSVEKLSRDGAF 984 Query: 982 LLENGLNLFLWVGASVQQGVVQSLFSVSSFSQITSGLSVLPVLDNPLSKKVRGLIDSLRA 1041 L++ G L LWVG + Q + + V +++ I ++ LP LD P S ++ I LR Sbjct: 985 LMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQPMTDLPELDTPESARIIAFISWLRE 1044 Query: 1042 QRSRYMKLTVVKQEDKMEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQ 1091 QR + L V++ E M+ F ++ED++ S SY +FL H+ +++ + Sbjct: 1045 QRPFFPILYVIRDESPMKANFLQNMIEDRTES-ALSYYEFLLHIQQQVNK 1093 Score = 42.4 bits (98), Expect = 0.002 Identities = 52/171 (30%), Positives = 71/171 (41%), Gaps = 26/171 (15%) Query: 151 PAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQA 210 P P+SG G P SL + +G+ SG Y G P+ A + + Q S SQ Sbjct: 4 PGIPASG---GAPASLQAQNGAALASG--SPYTNG---PVQNA-----LLSSQESV-SQG 49 Query: 211 SSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQM--TGPLGPLP 268 +F P S +P+ T + GQS G S ++ PP A P T +GP P Sbjct: 50 YNFQLPGSYPHPIPAKTLNPVSGQSNYGGSQGSGQTLNRPPVASNPVTPSLHSGP-APRM 108 Query: 269 PMHSPQQPGYQPQQNGSFGPARG--PQSNYGGPYPA-------APTFGSQP 310 P+ + Q P P + SF P P N+ YP+ P SQP Sbjct: 109 PLPASQNPATTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQP 159 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 92.8 bits (229), Expect = 2e-18 Identities = 109/362 (30%), Positives = 128/362 (35%), Gaps = 72/362 (19%) Query: 4 NQSVPPVPPFGQPQ------------PIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVP-G 50 NQ P PP G+PQ P PG Q S +P P G GP P G Sbjct: 66 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 125 Query: 51 YQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPF 110 Q PQG P PP P G G+ QG G + + + R P +P Sbjct: 126 GNQ--PQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGDNKS-RSSRSPPGKPQ 181 Query: 111 GSPLA----PVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSL 166 G P P G PP +P GPPP G PP G GPP Sbjct: 182 GPPPQGGNQPQGPPPPPGKPQGPPPQG-------------GNKPQGPPPPGKPQGPPPQG 228 Query: 167 ASASGSF----------PNSGLYGSYPQGQAPPLSQAQGHP--GIQTPQRSAPSQASSFT 214 + S S P G G+ PQG PP + QG P G PQ P Sbjct: 229 DNKSQSARSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNKPQ-GPPPPGKPQG 285 Query: 215 PPASGGPRLPSMTGPLLPGQSFGGPSV--SQPNHVSSPP---QALPP--GTQMTGPLGPL 267 PP GG + S P PG+ G P +QP PP Q PP G + GP P Sbjct: 286 PPPQGGSKSRSSRSP--PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343 Query: 268 PPMHSPQQPGYQ--------------PQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPP 313 P P Q G + PQQ G+ P + P AP G GPP Sbjct: 344 KPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP 403 Query: 314 QP 315 +P Sbjct: 404 RP 405 Score = 82.8 bits (203), Expect = 2e-15 Identities = 108/345 (31%), Positives = 123/345 (35%), Gaps = 61/345 (17%) Query: 2 NVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVP-GYQQTPPQGMS 60 +V+Q P G PQ P G + P P G GP P G Q PQG Sbjct: 22 DVSQEESPSLIAGNPQGAPPQ-------GGNKPQGPPSPPGKPQGPPPQGGNQ--PQGPP 72 Query: 61 RAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLA----P 116 P PP P G G+ QG G S + R P +P G P P Sbjct: 73 PPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGDKS--RSPRSPPGKPQGPPPQGGNQP 129 Query: 117 VGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSF--- 173 G PP +P GPPP G PP G GPP + S S Sbjct: 130 QGPPPPPGKPQGPPPQG-------------GNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176 Query: 174 -------PNSGLYGSYPQGQAPPLSQAQGHP--GIQTPQRSAPSQASSFTPPASGGPRLP 224 P G G+ PQG PP + QG P G PQ P PP G + Sbjct: 177 PGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNKPQ-GPPPPGKPQGPPPQGDNKSQ 233 Query: 225 SMTGPLLPGQSFGGPSV--SQPNHVSSPPQALPPGTQMTG---PLGPLPPMHSPQQPGYQ 279 S P PG+ G P +QP PP P G G P GP PP PQ P Sbjct: 234 SARSP--PGKPQGPPPQGGNQPQG-PPPPPGKPQGPPPQGGNKPQGP-PPPGKPQGP--- 286 Query: 280 PQQNGSFG-PARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDP 323 P Q GS +R P GP P G+QP P P P K P Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQG---GNQPQGPPPPPGKPQGP 328 Score = 80.5 bits (197), Expect = 8e-15 Identities = 103/330 (31%), Positives = 118/330 (35%), Gaps = 71/330 (21%) Query: 4 NQSVPPVPPFGQPQ------------PIYPGYHQSSYG-GQSGSTAPAIPYGAYNGPVP- 49 NQ P PP G+PQ P PG Q G + S + P G GP P Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186 Query: 50 GYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQP 109 G Q PQG P PP P G G+ QG G + + Q R P +P Sbjct: 187 GGNQ--PQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGDNKS-QSARSPPGKP 242 Query: 110 FGSPLA----PVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTS 165 G P P G PP +P GPPP G PP G GPP Sbjct: 243 QGPPPQGGNQPQGPPPPPGKPQGPPPQG-------------GNKPQGPPPPGKPQGPPPQ 289 Query: 166 LASASGSF----------PNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTP 215 S S S P G G+ PQG PP + QG P PQ Q P Sbjct: 290 GGSKSRSSRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPP----PQGGNKPQG----P 339 Query: 216 PASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPM-HSPQ 274 P G P+ GP G S + S P PPQ + P GP PP +PQ Sbjct: 340 PPPGKPQ-----GPPPQGGSKSRSARSPPGKPQGPPQQ-----EGNNPQGPPPPAGGNPQ 389 Query: 275 QPGYQPQQNGSFGPARGPQSNYGGPYPAAP 304 QP P GP R PQ G P+ P Sbjct: 390 QP-QAPPAGQPQGPPRPPQ----GGRPSRP 414 Score = 37.4 bits (85), Expect = 0.078 Identities = 41/133 (30%), Positives = 49/133 (36%), Gaps = 10/133 (7%) Query: 244 PNHVSSPPQALPP--GTQMTGPLGPL-PPMHSPQQPGYQPQQNGSFGPARGPQSN--YGG 298 P+ ++ PQ PP G + GP P P P Q G QPQ G P PQ GG Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQ--GPPPPPGKPQGPPPQGG 86 Query: 299 PYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVT 358 P P +P P P K P + P Q N+ P + Q PP Sbjct: 87 NKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 146 Query: 359 TNFLVKDQGNASP 371 N K QG P Sbjct: 147 GN---KPQGPPPP 156 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 81.3 bits (199), Expect = 5e-15 Identities = 91/311 (29%), Positives = 111/311 (35%), Gaps = 41/311 (13%) Query: 32 SGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDV 91 S +P++ G GP P PQG P PP P G G+ QG Sbjct: 24 SQEESPSLIAGNPQGPSP-QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPP 81 Query: 92 QNGPSSTVQMQRLPGSQPFGSPLA----PVGNQPPVLQPYGPPPTSAQVATQLSGMQISG 147 G S + R P +P G P P G PP +P GPPP Q + G G Sbjct: 82 PQGDKS--RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP---QGGNRPQGPPPPG 136 Query: 148 AVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHP--GIQTPQRS 205 PP P + G P G + PQG PP + QG P G + PQ Sbjct: 137 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGG---NQPQGPPPPPGKPQGPPPQGGKKPQGP 193 Query: 206 APSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSV--SQPNHVSSPP---QALPP--GT 258 P PP G + S P PG+ G P +QP PP Q PP G Sbjct: 194 PPPGKPQGPPPQ--GDKSRSSQSP--PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249 Query: 259 QMTGPLGPLPPMHSPQQPGYQ--------------PQQNGSFGPARGPQSNYGGPYPAAP 304 + GP P P P Q G + PQQ G+ P + P AP Sbjct: 250 KPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP 309 Query: 305 TFGSQPGPPQP 315 G GPP+P Sbjct: 310 PAGQPQGPPRP 320 Score = 81.3 bits (199), Expect = 5e-15 Identities = 99/328 (30%), Positives = 114/328 (34%), Gaps = 70/328 (21%) Query: 4 NQSVPPVPPFGQPQ------------PIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVP-G 50 N+ P PP G+PQ P PG Q S +P P G GP P G Sbjct: 45 NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 104 Query: 51 YQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPF 110 Q PQG P PP P G G+ QG G S + R P +P Sbjct: 105 GNQ--PQGPPPPPGKPQGPPPQGGNRPQGPPPPGK-PQGPPPQGDKS--RSPRSPPGKPQ 159 Query: 111 GSPLA----PVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSL 166 G P P G PP +P GPPP G PP G GPP Sbjct: 160 GPPPQGGNQPQGPPPPPGKPQGPPPQG-------------GKKPQGPPPPGKPQGPPPQG 206 Query: 167 ASASGSFPNSGLY-------GSYPQGQAPPLSQAQGHP--GIQTPQRSAPSQASSFTPPA 217 + S G G+ PQG PP + QG P G PQ P PPA Sbjct: 207 DKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ-GPPPPGKPQGPPA 265 Query: 218 SGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPM-HSPQQP 276 GG + S P PG+ G PP + P GP PP +PQQP Sbjct: 266 QGGSKSQSARSP--PGKPQG-----------------PPQQEGNNPQGPPPPAGGNPQQP 306 Query: 277 GYQPQQNGSFGPARGPQSNYGGPYPAAP 304 P GP R PQ G P+ P Sbjct: 307 -QAPPAGQPQGPPRPPQ----GGRPSRP 329 Score = 68.9 bits (167), Expect = 2e-11 Identities = 73/251 (29%), Positives = 85/251 (33%), Gaps = 46/251 (18%) Query: 90 DVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAV 149 DV S ++ G P G P G PP +P GPPP Q + G G Sbjct: 22 DVSQEESPSLIAGNPQGPSPQGGN-KPQGPPPPPGKPQGPPP---QGGNKPQGPPPPGKP 77 Query: 150 APAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQ 209 PP P + G P G + PQG PP + QG Sbjct: 78 QGPPPQGDKSRSPRSPPGKPQGPPPQGG---NQPQGPPPPPGKPQG-------------- 120 Query: 210 ASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTG---PLGP 266 PP GG R GP PG+ G P + P P G G P GP Sbjct: 121 -----PPPQGGNR---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 172 Query: 267 LPPMHSPQQP----GYQPQQNGSFGPARGP----------QSNYGGPYPAAPTFGSQPGP 312 PP PQ P G +PQ G +GP QS G P P G+QP Sbjct: 173 PPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQG 232 Query: 313 PQPLPPKRLDP 323 P P P K P Sbjct: 233 PPPPPGKPQGP 243 Score = 43.9 bits (102), Expect = 8e-04 Identities = 54/178 (30%), Positives = 61/178 (34%), Gaps = 40/178 (22%) Query: 180 GSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGP 239 G+ PQG PP + QG P PQ Q PP G P+ P P Q G Sbjct: 44 GNKPQGPPPPPGKPQGPP----PQGGNKPQG----PPPPGKPQGP-------PPQ---GD 85 Query: 240 SVSQPNHVSSPPQALPP--GTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYG 297 P PQ PP G Q P GP PP PQ P P +G G Sbjct: 86 KSRSPRSPPGKPQGPPPQGGNQ---PQGPPPPPGKPQGP-----------PPQGGNRPQG 131 Query: 298 GPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPP 355 P P P GPP P K P + P Q N+ P + Q PP Sbjct: 132 PPPPGKPQ-----GPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 183 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 81.3 bits (199), Expect = 5e-15 Identities = 95/334 (28%), Positives = 114/334 (34%), Gaps = 64/334 (19%) Query: 33 GSTAPAIPYGAYNGPVPGYQQTP-PQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDV 91 G A P GA P+P P P+G PP GAP A P + Sbjct: 1092 GGPATPSPKGA---PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148 Query: 92 QNGPSSTVQMQR--LPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAV 149 P++T + L P G+P P P P G + A Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPS--------PKGGLATPSPKGAPTTPAA 1200 Query: 150 APAPPSSGLGF----GPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRS 205 P P GL G PT+ A+ S P GL P+G AP TP + Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPS-PKGGLATPSPKG-APT-----------TPAAT 1247 Query: 206 APS-QASSFTPPASGGPRLPSMTGPLL-------------------PGQSFGGPSVSQPN 245 PS + TPP G P P+ T P L P GGP+ S P Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307 Query: 246 HVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQP--QQNGSFGPARGPQSNYG------ 297 +PP A PP + G G PP +P P P + PA P S G Sbjct: 1308 GAPTPPAATPPSPK--GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365 Query: 298 --GPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSP 329 GP P A T S G P PP AIPSP Sbjct: 1366 KEGPTPPAAT-PSHKGGPAMTPPSPKRGPAIPSP 1398 Score = 78.2 bits (191), Expect = 4e-14 Identities = 107/448 (23%), Positives = 145/448 (32%), Gaps = 74/448 (16%) Query: 6 SVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTP------PQGM 59 + PP P G P G + +T P+ G P G TP P+G Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTP-----AATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185 Query: 60 SRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQR--LPGSQPFGSPLAPV 117 P GAP A P + P++T + L P G+P P Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245 Query: 118 GNQP-PVLQPYGPPPTSAQVATQLSGMQISGAVAPAP--------------PSSGLGFGP 162 P P P PPP A + + G +A P P G P Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305 Query: 163 PTSLASASGSFPNSGLYGSYPQGQ--APPLSQAQGHPGIQTPQRSAPSQASSFTPPASGG 220 P + + P S P+G PP A P + P + TP + GG Sbjct: 1306 PKGAPTPPAATPPS------PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359 Query: 221 PRLPSMT-GPLLPGQS---FGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQP 276 P PS GP P + GGP+++ P+ P P G + + PL P +P P Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419 Query: 277 -----GYQPQQNGSFGPARGPQSNYGGPY-------PAAPTFGSQPGPPQPLPPKRLDPD 324 P + PA P S P PA P+ P P PP +P Sbjct: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP- 1478 Query: 325 AIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCT 384 P+P QV + P G P L P I + +P T Sbjct: 1479 --PAPKQVATSSSPKKA--PATPAPMG-APTL--------------PAVIPSSPKEVPAT 1519 Query: 385 SDMAKQAQVPLAAVI--KPLARLPPEEA 410 + P A ++ K A L P+EA Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEA 1547 Score = 73.6 bits (179), Expect = 1e-12 Identities = 86/311 (27%), Positives = 106/311 (34%), Gaps = 44/311 (14%) Query: 36 APAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAP--PASTAQAPCGQAAYGQFGQGDVQN 93 APA+ + + P P+G+ +P GAP PA+T +P G G Sbjct: 908 APALSMTS-SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG---------GPATP 957 Query: 94 GPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAP 153 P P G P P P PP AT S AP P Sbjct: 958 SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP------SPKGAPTP 1011 Query: 154 PSSGLGFGPPTSLAS-ASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASS 212 P+ PP+ S A+ FP S P PP +G P + AP+ ++ Sbjct: 1012 PA----VTPPSPKGSPAATPFPKGA---STPPAATPP--SPKGSPAATPLPKGAPTTPAA 1062 Query: 213 FTPPASGGPRLPSMTG-----PLLPGQSFGGPSVSQPNHVSSPPQALPP---GTQMTGPL 264 P GGP PS+ G P GGP+ P PP A PP G T P Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122 Query: 265 --GPLPPMHSPQQP----GYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPP 318 P P +P P P + PA P S GG A P P P PP Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG--LATPPPKGAPTTPAATPP 1180 Query: 319 KRLDPDAIPSP 329 A PSP Sbjct: 1181 SPKGGLATPSP 1191 Score = 68.2 bits (165), Expect = 4e-11 Identities = 82/330 (24%), Positives = 104/330 (31%), Gaps = 72/330 (21%) Query: 31 QSGSTAPAIPYGAYNGPVP---------------GYQQTPPQGMSRAPPSSGAPPASTAQ 75 + GS P P G + PV G + +P S PPS P +A Sbjct: 811 KKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAV 870 Query: 76 APCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQ 135 P V P T + P P P Q P L P A+ Sbjct: 871 TPLSPKG--------VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922 Query: 136 VATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQG 195 G+ PA PS G PT P PP +G Sbjct: 923 ATPAPKGI-------PASPSPK---GAPT------------------PPAATPP--SPKG 952 Query: 196 HPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSF-----GGPSVSQPNHVSSP 250 P +P + AP+ ++ P GGP PS G P + GGP+ P +P Sbjct: 953 GPATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011 Query: 251 PQALPPGTQMTGPLGPL------PPMHSPQQPGYQP-----QQNGSFGPARGPQSNYGGP 299 P PP + + P PP +P P P + PA S GG Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG- 1070 Query: 300 YPAAPTFGSQPGPPQPLPPKRLDPDAIPSP 329 PA P+ P PP PP A PSP Sbjct: 1071 -PATPSLKGAPTPPAATPPSPKGGPATPSP 1099 Score = 60.8 bits (146), Expect = 7e-09 Identities = 88/352 (25%), Positives = 121/352 (34%), Gaps = 61/352 (17%) Query: 8 PPV--PPFGQPQPIYPGYHQSSYGG------QSGSTAPAIPYGAYNGPV---PGYQQTP- 55 PP PP + P P SS GG + G T PA GP P ++ P Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394 Query: 56 ---PQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPG-SQPFG 111 P+G +P P P + +GD+ + V +++ P S P G Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454 Query: 112 SPLAPVGNQPPVLQPYGPP-----PTSAQVATQLSGMQISGAVAP--------------- 151 P P P L PP P QVAT S + AP Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK 1514 Query: 152 ---APPSSGLG-FGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRS-- 205 A PSS P +L S + P P + P I TP+ + Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT--PAIPTPKEAPA 1572 Query: 206 APSQASSFTPPA------SGGPRL------PSMTGPLLPGQSFGGPSVSQPNHVSSPPQA 253 PS + +PPA G P P++T P P ++ P+V+ P+ P Sbjct: 1573 TPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS-PKEAPTPPAVTPPSPEKGPATP 1631 Query: 254 LPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPT 305 P GT + P+ P SP P + G A PQ++ G P PT Sbjct: 1632 APKGTPTSPPVTPSSLKDSPTSPASVTCKMG----ATVPQASKGLPAKKGPT 1679 Score = 47.0 bits (110), Expect = 1e-04 Identities = 72/295 (24%), Positives = 106/295 (35%), Gaps = 38/295 (12%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQS--GSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPS 65 PP P Q P+ S + S ST +P+ + T P+ + P Sbjct: 47 PPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNL 106 Query: 66 SGAP--PASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPV 123 G P PA+ A A S + L G+ +PLA V P Sbjct: 107 IGPPISPAALALA--------------------SPMIAPTLKGTPSSSAPLALVALAPHS 146 Query: 124 LQPYG--PP-----PTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNS 176 +Q PP P S VA S + +S +AP+ P + L P + + G+ Sbjct: 147 VQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPP 206 Query: 177 GLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPS-MTGPLLPGQ- 234 + + P P++ Q G+ + ++ P+ + P + S + P PG Sbjct: 207 CIVSTVPYHCVTPMASIQS--GVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSL 264 Query: 235 SFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPG--YQPQQNGSFG 287 S GP VS P +S Q+LP T GP P P G P SFG Sbjct: 265 SLKGP-VSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFG 318 Score = 35.4 bits (80), Expect = 0.30 Identities = 102/466 (21%), Positives = 160/466 (34%), Gaps = 74/466 (15%) Query: 6 SVPPVPPFGQPQPIYPGYHQSSYG-----GQSGSTAPAIP---------------YGAYN 45 + PP P + P HQSS+G GQ+G +A + P Y + Sbjct: 296 NTPPDFPISLGSHLAP-LHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQR 354 Query: 46 G---PVPGYQQTPPQGMSRAP---PSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTV 99 P+P + P ++ P PS P++ + C + P++++ Sbjct: 355 SVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATS-FSLSPTTSL 413 Query: 100 QMQRLPGSQ---PFGS--PLAPVGNQPPVLQP----YGPPPTSAQVATQLSGMQISGAVA 150 ++ P + P + P++ VG P V+ P T+ +VAT +S SG ++ Sbjct: 414 ILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPIS 473 Query: 151 PAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQR-SAPSQ 209 P+S +A + P++ + + +PPL + + + P+Q Sbjct: 474 NIEPTSPAAL----VMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQ 529 Query: 210 ASSFTPPAS--GGPRLPSMTG----------PLLPGQSFGGPSVSQPNHVSSPPQAL-PP 256 T PAS G P P+ G PL+ PS + SSP L P Sbjct: 530 KDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTS--SSPEIPLSPE 587 Query: 257 GTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPP--Q 314 T LG P+ P P S S Y GP A P S P Sbjct: 588 ATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDS-YAGPDSAGPLLKSSLITPTVA 646 Query: 315 PLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYI 374 P + DP + +P PF+ G P N VK+ + + Sbjct: 647 AFPLESADPAGV-APTTAKGTSTYTTTASPFLEGTVSLAP----KNHPVKEGTLTTLPLV 701 Query: 375 RCTSYNIPCTSDMAKQAQVPLAAVI--------KPLARLPPEEASP 412 S N P + + PLA ++ P LPP P Sbjct: 702 PTASENCP-VAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPP 746 >gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] Length = 1336 Score = 81.3 bits (199), Expect = 5e-15 Identities = 111/362 (30%), Positives = 123/362 (33%), Gaps = 86/362 (23%) Query: 1 MNVNQSVPPVP--------PFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQ 52 MN+ Q PP P P GQ P P HQ GG G P P G G Sbjct: 612 MNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGG-GGPQGFMGPQGPQGPPQGLPRPQD 670 Query: 53 QTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGS 112 PQGM R P G P G + GP + Q PG Q Sbjct: 671 MHGPQGMQRHPGPHGPLGPQGPPGPQGSS------------GPQGHMGPQGPPGPQGHIG 718 Query: 113 PLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGS 172 P P G Q L P GPP T GMQ P P G P + GS Sbjct: 719 PQGPPGPQGH-LGPQGPPGTQ--------GMQ-----GPPGPRGMQGPPHPHGIQGGPGS 764 Query: 173 FPNSGLYGSYPQGQAPPLSQA--QGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPL 230 G+ G QG L+ QG PG + Q AP PP M GP Sbjct: 765 ---QGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQE-------MRGPH 814 Query: 231 LPGQSFG-GPSVSQ-PNHVSS------------PPQAL--PPGTQMT-----GPLGPLPP 269 PG G GP + P + PPQ L PPG+Q G LGP P Sbjct: 815 PPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQ 874 Query: 270 MHSPQQPGYQPQQNGSFGPARGPQSNYG------------GPYPAAP--TFGSQPGPPQP 315 PG Q QQN PARGP + G G P AP G GPP Sbjct: 875 GGMQGPPGPQGQQN----PARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPL 930 Query: 316 LP 317 +P Sbjct: 931 IP 932 Score = 65.5 bits (158), Expect = 3e-10 Identities = 109/377 (28%), Positives = 128/377 (33%), Gaps = 88/377 (23%) Query: 63 PPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQ-------------RLPGSQ- 108 PPSSG P P GQ Q QG Q PS + M R PG Q Sbjct: 575 PPSSGTPLLGPQPFP-GQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 Query: 109 ---PFGSPLAPVGNQPP-VLQPYGP--PPTSAQVATQLSGMQISGAVAPAPPSSGLGFGP 162 P G PL G P + P GP PP + G Q G P LG Sbjct: 634 QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQ--GMQRHPGPHGPLGPQG 691 Query: 163 PTSLASASGSFPNSGLYG-SYPQG----QAPPLSQA----QGHPGIQTPQRSAPSQASSF 213 P +SG + G G PQG Q PP Q QG PG Q Q P Sbjct: 692 PPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQ-GPPGPRGMQ 750 Query: 214 TPP----ASGGPRLPSMTGPLLPGQSFG-------GPSVSQPNHVSSPPQALPPGTQMTG 262 PP GGP + GP+ G G GP + N PQ + G Sbjct: 751 GPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQ-GPAPQGMIMGHPPQE 809 Query: 263 PLGPLPP----MHSPQQ-------PGYQ--PQQNGSFGP---ARGP---QSNYGGPYPA- 302 GP PP H PQ+ G Q P Q GP RGP QS G P + Sbjct: 810 MRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSL 869 Query: 303 -APTFGSQPGPPQPL----PPKRLDPDAIPSPIQ-------------VIEDDRNNRGTEP 344 P G GPP P P + P P P Q + + G P Sbjct: 870 GPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPP 929 Query: 345 FVTGV-----RGQVPPL 356 + G+ +G++PPL Sbjct: 930 LIPGLGQQGAQGRIPPL 946 Score = 62.8 bits (151), Expect = 2e-09 Identities = 76/294 (25%), Positives = 96/294 (32%), Gaps = 58/294 (19%) Query: 48 VPGYQQTPPQGMSRAPPSS-GAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPG 106 + G Q PPQG PP PP S +Q Q + G QG +Q P Sbjct: 833 IRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPG---------- 882 Query: 107 SQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAP-PSSGLGFGPPTS 165 P G Q P GP P+ + Q + G AP G GPP Sbjct: 883 ---------PQGQQNPAR---GPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPL 930 Query: 166 LASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQ----ASSFTPPASGGP 221 + P G G+ QG+ PPL+ QG + R P+ S SGGP Sbjct: 931 I-------PGLGQQGA--QGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP 981 Query: 222 RLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPG------------TQMTGPLGPLPP 269 GP GQ GP + H P P + G GPLP Sbjct: 982 EHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQ 1041 Query: 270 MHSPQQPGYQP---------QQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQ 314 ++ G P + G ARGP + G P F P P+ Sbjct: 1042 EEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPR 1095 Score = 39.3 bits (90), Expect = 0.021 Identities = 38/120 (31%), Positives = 43/120 (35%), Gaps = 20/120 (16%) Query: 203 QRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPS----VSQPNHVSSPPQALPPGT 258 +R A Q PP S G PLL Q F G + Q P Q +P Sbjct: 562 ERLAQKQVEQIQPPPSSGT-------PLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNM 614 Query: 259 QMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQP-GPPQPLP 317 GP G PQ P G GP +GP + GG P P GPPQ LP Sbjct: 615 AQMGPPG-------PQGQFRPPGPQGQMGP-QGPPLHQGGGGPQGFMGPQGPQGPPQGLP 666 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 80.1 bits (196), Expect = 1e-14 Identities = 117/430 (27%), Positives = 150/430 (34%), Gaps = 91/430 (21%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSG----STAPAIPYGAYNGPVPGYQQTPPQGMSRAP 63 P V P P I+P SS S S+ P + P QTPP ++ P Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP 534 Query: 64 ----PSSGAPPASTAQAP----------CGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQP 109 PS PP TA AP C Q + P T P Q Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594 Query: 110 FGSPLAPV--GNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTS-L 166 + +P G P L P PP A L +Q P+PP+S PP S L Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ----APPSPPAS-----PPLSPL 645 Query: 167 ASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTP--QRSAPSQASSFTPPASGGPRLP 224 A+ S PN+ +PP S P +Q P ++P + S TPP+ P Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPS-----PPVQAPFSPPASPPVSPSATPPSQAPP--- 697 Query: 225 SMTGPLLPGQSFGGPSVSQPNHVSS--PPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQ 282 S+ P P Q P S P S+ PPQA PP + P PP P P P Sbjct: 698 SLAAP--PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP-- 753 Query: 283 NGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGT 342 P R P P AAP P PP LP + P A P P Sbjct: 754 -----PPRVP------PLLAAPPLQVPPSPPASLP---MSPLAKPPP------------- 786 Query: 343 EPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPL 402 Q PP + T L Q SP + P + + A +P++ + P Sbjct: 787 ---------QAPPALATPPL---QALPSP------PASFPGQAPFSPSASLPMSPLATPP 828 Query: 403 ARLPPEEASP 412 + PP A+P Sbjct: 829 PQAPPVLAAP 838 Score = 71.6 bits (174), Expect = 4e-12 Identities = 97/348 (27%), Positives = 125/348 (35%), Gaps = 62/348 (17%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPA----IPYGAYNGPVPGYQQTPPQGMSRAP 63 PP+ P P P P S P+ P+ P TPP S+AP Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP---SQAP 696 Query: 64 PSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPV 123 PS APP +P Q P ++P S P P++P PP Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756 Query: 124 LQPY--GPP---PTSAQVATQLSGM-----QISGAVA-------PAPPSSGLGFGPPTSL 166 + P PP P S + +S + Q A+A P+PP+S G P Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP---- 812 Query: 167 ASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSM 226 S S S P S L + P QAPP+ A P +Q P PS +S P PR P Sbjct: 813 FSPSASLPMSPL--ATPPPQAPPVLAA---PLLQVP----PSPPAS---PTLQAPRRPPT 860 Query: 227 TGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPL-GPLPPMHS------PQQ-PGY 278 G P S GP ++ PP PP + L GP HS P++ GY Sbjct: 861 PG---PDTSVSGPRLTLALAPGPPP---PPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 914 Query: 279 QPQQNGSFGPARGPQSNYGGPYPAA--------PTFGSQPGPPQPLPP 318 G + P + +PAA F PG P P PP Sbjct: 915 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962 Score = 66.2 bits (160), Expect = 2e-10 Identities = 121/494 (24%), Positives = 169/494 (34%), Gaps = 115/494 (23%) Query: 6 SVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPV--------PGYQQTPPQ 57 ++PP PP P P+ P + Q+ + PA P + P Q PP Sbjct: 330 TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI 389 Query: 58 GM--SRAPPSSGAPPA----STAQA------PCGQAAYGQFGQGDVQNGPSSTVQMQRL- 104 + S PS APP+ S+ QA P QA + Q S T + Sbjct: 390 QVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449 Query: 105 --PGSQPFGSPLAPVGNQP--PVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGF 160 P S P +PL+ + P L P P +S L + + +P P S L Sbjct: 450 TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIM 509 Query: 161 GP---PTSLASASGSFPNSGL----YGSYPQGQAPPLSQAQGH---PGIQTPQRSAP--- 207 P +SLA S P + L + P PPL A P ++TP AP Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569 Query: 208 -------------SQASSFTPPASGGPRL--PSMTG-PLLPGQSFGGPSVSQPNHVSSPP 251 + +S TPP P L P + G P P P P ++ PP Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629 Query: 252 QALPPGTQMTGPLGPL-------------------------PPMHSPQQPGYQPQQNGSF 286 PP + PL PL PP+ +P P P + S Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 689 Query: 287 GP-ARGPQSNYGGPY------PAAPTFG-SQPGPPQPLPPKRLDPDAIPSPIQVIEDDRN 338 P ++ P S P PA+P S PPQ PP P +P P + Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP-PSPPASPPMS 748 Query: 339 NRGTEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAV 398 T P +VPPL+ A+P P + A +P++ + Sbjct: 749 PSATPP------PRVPPLL-----------AAP----------PLQVPPSPPASLPMSPL 781 Query: 399 IKPLARLPPEEASP 412 KP + PP A+P Sbjct: 782 AKPPPQAPPALATP 795 Score = 42.4 bits (98), Expect = 0.002 Identities = 80/330 (24%), Positives = 113/330 (34%), Gaps = 62/330 (18%) Query: 26 SSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQ 85 SS G SG+T P P G G ++T +G + P A A + Sbjct: 115 SSPGRASGTTRPG-PLGQ-KGLRISAEETVARGKATEAPKRSALSAGARRDT-------- 164 Query: 86 FGQGDVQNGPSSTVQMQRLPGSQPFGSPL-APVGNQPPVLQPYGPPPTSAQVATQLSGMQ 144 G PS + + G P AP P P P S A++ S + Sbjct: 165 --SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP---PTEGPRKSVSSASEHSTTE 219 Query: 145 ISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLS------------Q 192 S A A PS+G G P S + +S + P S S P + P + Q Sbjct: 220 PSPA-ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278 Query: 193 AQGHPGIQTPQRSA-----PSQASSFTPPASGGPRL-----PSMTGPLLPGQSFGGPSVS 242 A P + P++ A P +S P+ G + P LP P ++ Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338 Query: 243 QPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPA 302 P ++ P + PP Q T P P P P++ P S P A Sbjct: 339 TPLPLAPPSPSAPPSLQ-TLPSPPATP------------------PSQAPPSMTTPPMQA 379 Query: 303 APTFGSQPGPPQPLPPKRLDP--DAIPSPI 330 P+ Q PP +P P A PSP+ Sbjct: 380 PPSL--QTIPPIQVPHSLTSPSLQAPPSPL 407 Score = 32.7 bits (73), Expect = 1.9 Identities = 59/238 (24%), Positives = 84/238 (35%), Gaps = 61/238 (25%) Query: 122 PVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGS 181 P P PPP + L +GAV P LA +G + + S Sbjct: 29 PPGSPRPPPPVTPAALRVLGA---AGAVGRKP------------LAERAGGIGGATIPES 73 Query: 182 YPQGQAPPLSQAQGHPGIQTPQRSA--PSQASSFTPPASG-GPRLPSMTGPLLPGQSFGG 238 P+ P RSA S+ + PPASG G R P P ++ Sbjct: 74 APRA---------------GPTRSAGTSSRNPASRPPASGRGERAP-------PAKN--- 108 Query: 239 PSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQP---GYQPQQNGSFGPARGPQSN 295 + P VSSP +A GT GPLG S ++ G + + G + + Sbjct: 109 ---TSPGPVSSPGRA--SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 163 Query: 296 YGGPYPAAPT---------FGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEP 344 GP P P+ G++ G P+P P R P P + + + TEP Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT-EGPRKSVSSASEHSTTEP 220 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 75.1 bits (183), Expect = 3e-13 Identities = 94/322 (29%), Positives = 115/322 (35%), Gaps = 47/322 (14%) Query: 33 GSTAPAIPYGAYNGPVPGYQQTPPQGMSRAP-PS----SGAPPASTAQAPCGQAAYGQFG 87 GS P +P G + + +PP G R P PS SG P + P + G Sbjct: 123 GSRPPLLPPGGRSTSAKPF--SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180 Query: 88 QGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISG 147 PS+ +Q P ++ GSP P G + P P PPP T L G G Sbjct: 181 DSIPPPVPSTPRPIQSSPHNR--GSPPVPGGPRQPSPGPT-PPPFPGNRGTALGG----G 233 Query: 148 AVAPAPPSSGLGFG-----PPT-SLASASGSFPNSGLYGSYP----QGQAPPLSQAQGHP 197 ++ +P SS F PPT S A P G+ P + PP Q P Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293 Query: 198 GIQTPQRSAPSQASSFTPPAS--GGPRLP-------------------SMTGPLLPGQSF 236 TP+ SA SQA PP S G P LP S + P LP Sbjct: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR 353 Query: 237 GGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNY 296 GP P+ PP PPG +GPL P PP+ G S Sbjct: 354 SGPLPPPPSERPPPPVRDPPGR--SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPR 411 Query: 297 GGPYPAAPTFGSQPGPPQPLPP 318 GP P P G P P PP Sbjct: 412 SGPRPPLPPDRPSAGAPPPPPP 433 Score = 66.2 bits (160), Expect = 2e-10 Identities = 86/312 (27%), Positives = 110/312 (35%), Gaps = 25/312 (8%) Query: 29 GGQSGSTAPAIPYGAYNGPVPGYQQTPPQ----GMSRAP---PSSGAPPASTAQAPCGQA 81 GG G P G + +P + T + G SR P P + A P G Sbjct: 89 GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPG 148 Query: 82 AYGQFGQGDVQNGPSSTVQMQRLPGSQP-FGSPLAPVGNQPPVLQPYGPPPTSAQVATQL 140 + G ++GP Q R+P +P GS P PPV P P P + + Sbjct: 149 RFPVPSPGH-RSGPPEP-QRNRMPPPRPDVGSK--PDSIPPPV--PSTPRPIQSSPHNRG 202 Query: 141 SGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQ 200 S G P+P + F A GS S L S P PPL Sbjct: 203 SPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP-------- 254 Query: 201 TPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPN-HVSSPPQALPPGTQ 259 TP R+ + PP P + P P Q+ P S P SS PP Sbjct: 255 TPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS 314 Query: 260 MTGPLGPLPPMHSPQQPGYQ-PQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPP 318 GP PLPP S + PQ+N S + P + G P P +P PP PP Sbjct: 315 RPGP-PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPP 373 Query: 319 KRLDPDAIPSPI 330 R P P P+ Sbjct: 374 GRSGPLPPPPPV 385 Score = 55.5 bits (132), Expect = 3e-07 Identities = 75/320 (23%), Positives = 111/320 (34%), Gaps = 71/320 (22%) Query: 29 GGQSGSTAPAIPY---GAYNGPVPGYQQTPPQGM-SRAPP---------SSGAPPASTAQ 75 GG+S S P P G + P PG++ PP+ +R PP S PP + Sbjct: 132 GGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTP 191 Query: 76 APCGQAAYGQFGQGDVQNGP---------------------SSTVQMQRLPGSQPFGS-- 112 P + + + G V GP +++ L S PF + Sbjct: 192 RPIQSSPHNR-GSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRP 250 Query: 113 ----------------PLAPVGNQPPVLQPY--GPPPTSAQVATQLSGMQISGAVAPAPP 154 P PVGN+P + + PPP + + + + + AP PP Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310 Query: 155 SSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFT 214 GPP S+SG+ + P L Q TP +P ++ Sbjct: 311 PPPSRPGPPPLPPSSSGN------------DETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358 Query: 215 PPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQ 274 PP S P P + P PG+S P + S +ALP Q+ G P P+ Sbjct: 359 PPPSERPP-PPVRDP--PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR 415 Query: 275 QPGYQPQQNGSFGPARGPQS 294 P P + + P P S Sbjct: 416 PP-LPPDRPSAGAPPPPPPS 434 Score = 43.9 bits (102), Expect = 8e-04 Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 25/107 (23%) Query: 265 GPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQP----LPPKR 320 G PP+ PG + F P GP G +P P+ G + GPP+P +PP R Sbjct: 123 GSRPPL---LPPGGRSTSAKPFSPPSGP-----GRFPV-PSPGHRSGPPEPQRNRMPPPR 173 Query: 321 LD----PDAIPSPI----QVIEDDRNNRGTEPFVTGVR----GQVPP 355 D PD+IP P+ + I+ +NRG+ P G R G PP Sbjct: 174 PDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 75.1 bits (183), Expect = 3e-13 Identities = 94/322 (29%), Positives = 115/322 (35%), Gaps = 47/322 (14%) Query: 33 GSTAPAIPYGAYNGPVPGYQQTPPQGMSRAP-PS----SGAPPASTAQAPCGQAAYGQFG 87 GS P +P G + + +PP G R P PS SG P + P + G Sbjct: 123 GSRPPLLPPGGRSTSAKPF--SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180 Query: 88 QGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISG 147 PS+ +Q P ++ GSP P G + P P PPP T L G G Sbjct: 181 DSIPPPVPSTPRPIQSSPHNR--GSPPVPGGPRQPSPGPT-PPPFPGNRGTALGG----G 233 Query: 148 AVAPAPPSSGLGFG-----PPT-SLASASGSFPNSGLYGSYP----QGQAPPLSQAQGHP 197 ++ +P SS F PPT S A P G+ P + PP Q P Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293 Query: 198 GIQTPQRSAPSQASSFTPPAS--GGPRLP-------------------SMTGPLLPGQSF 236 TP+ SA SQA PP S G P LP S + P LP Sbjct: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR 353 Query: 237 GGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNY 296 GP P+ PP PPG +GPL P PP+ G S Sbjct: 354 SGPLPPPPSERPPPPVRDPPGR--SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPR 411 Query: 297 GGPYPAAPTFGSQPGPPQPLPP 318 GP P P G P P PP Sbjct: 412 SGPRPPLPPDRPSAGAPPPPPP 433 Score = 66.2 bits (160), Expect = 2e-10 Identities = 86/312 (27%), Positives = 110/312 (35%), Gaps = 25/312 (8%) Query: 29 GGQSGSTAPAIPYGAYNGPVPGYQQTPPQ----GMSRAP---PSSGAPPASTAQAPCGQA 81 GG G P G + +P + T + G SR P P + A P G Sbjct: 89 GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPG 148 Query: 82 AYGQFGQGDVQNGPSSTVQMQRLPGSQP-FGSPLAPVGNQPPVLQPYGPPPTSAQVATQL 140 + G ++GP Q R+P +P GS P PPV P P P + + Sbjct: 149 RFPVPSPGH-RSGPPEP-QRNRMPPPRPDVGSK--PDSIPPPV--PSTPRPIQSSPHNRG 202 Query: 141 SGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQ 200 S G P+P + F A GS S L S P PPL Sbjct: 203 SPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP-------- 254 Query: 201 TPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPN-HVSSPPQALPPGTQ 259 TP R+ + PP P + P P Q+ P S P SS PP Sbjct: 255 TPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS 314 Query: 260 MTGPLGPLPPMHSPQQPGYQ-PQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPP 318 GP PLPP S + PQ+N S + P + G P P +P PP PP Sbjct: 315 RPGP-PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPP 373 Query: 319 KRLDPDAIPSPI 330 R P P P+ Sbjct: 374 GRSGPLPPPPPV 385 Score = 55.5 bits (132), Expect = 3e-07 Identities = 75/320 (23%), Positives = 111/320 (34%), Gaps = 71/320 (22%) Query: 29 GGQSGSTAPAIPY---GAYNGPVPGYQQTPPQGM-SRAPP---------SSGAPPASTAQ 75 GG+S S P P G + P PG++ PP+ +R PP S PP + Sbjct: 132 GGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTP 191 Query: 76 APCGQAAYGQFGQGDVQNGP---------------------SSTVQMQRLPGSQPFGS-- 112 P + + + G V GP +++ L S PF + Sbjct: 192 RPIQSSPHNR-GSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRP 250 Query: 113 ----------------PLAPVGNQPPVLQPY--GPPPTSAQVATQLSGMQISGAVAPAPP 154 P PVGN+P + + PPP + + + + + AP PP Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310 Query: 155 SSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFT 214 GPP S+SG+ + P L Q TP +P ++ Sbjct: 311 PPPSRPGPPPLPPSSSGN------------DETPRLPQRNLSLSSSTPPLPSPGRSGPLP 358 Query: 215 PPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQ 274 PP S P P + P PG+S P + S +ALP Q+ G P P+ Sbjct: 359 PPPSERPP-PPVRDP--PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR 415 Query: 275 QPGYQPQQNGSFGPARGPQS 294 P P + + P P S Sbjct: 416 PP-LPPDRPSAGAPPPPPPS 434 Score = 43.9 bits (102), Expect = 8e-04 Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 25/107 (23%) Query: 265 GPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQP----LPPKR 320 G PP+ PG + F P GP G +P P+ G + GPP+P +PP R Sbjct: 123 GSRPPL---LPPGGRSTSAKPFSPPSGP-----GRFPV-PSPGHRSGPPEPQRNRMPPPR 173 Query: 321 LD----PDAIPSPI----QVIEDDRNNRGTEPFVTGVR----GQVPP 355 D PD+IP P+ + I+ +NRG+ P G R G PP Sbjct: 174 PDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 74.7 bits (182), Expect = 4e-13 Identities = 99/394 (25%), Positives = 139/394 (35%), Gaps = 44/394 (11%) Query: 47 PVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPG 106 P P + PP R SS + ++T +P + G +Q S ++ P Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS--AGGGLQRPASRSLSSSATPL 249 Query: 107 SQPF-------GSPLAPVGNQPPV---LQPYGPP---PTSAQVATQLSGMQISGAVAPAP 153 S P G+P AP P LQ PP P A L + S P+P Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309 Query: 154 PSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQT---PQRSAPSQA 210 ++ PPT A+ S L + P APP A P +QT P + PSQA Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQL--ATPLPLAPPSPSAP--PSLQTLPSPPATPPSQA 365 Query: 211 SSFTPPASGGPRLPSMTG--PLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLP 268 ++ + G P L + P P P P ++ PP PP + PL PL Sbjct: 366 TT----SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421 Query: 269 PMHSPQQPGYQPQQ--NGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAI 326 SPQ P F P P PA+P P P PP + P Sbjct: 422 TP-SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-----PVSPSATPPSQAPPSLA 475 Query: 327 PSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTNF-LVKDQGNASP-------RYIRCTS 378 P+QV + P T PPL L K A P + + Sbjct: 476 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535 Query: 379 YNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASP 412 + P + + A +P++ + P + PP A+P Sbjct: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 569 Score = 74.3 bits (181), Expect = 6e-13 Identities = 86/325 (26%), Positives = 119/325 (36%), Gaps = 46/325 (14%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG 67 P PP Q P P S GS + P TPP +APP+ Sbjct: 345 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP---QAPPALA 401 Query: 68 APPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQP--PVLQ 125 PP +P Q + V + + P S P P+ + P P + Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461 Query: 126 PYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQG 185 P PP+ A + +Q V P+PP+S PP S ++ P Sbjct: 462 PSATPPSQAPPSLAAPPLQ----VPPSPPAS-----PPMSPSAT-------------PPP 499 Query: 186 QAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQP- 244 QAPP A + P ++ P+ A TPP P P+ PGQ+ PS S P Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALA---TPPLQALPSPPAS----FPGQAPFSPSASLPM 552 Query: 245 NHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAP 304 + +++PP PP + PL +PP P P Q + P GP ++ GP Sbjct: 553 SPLATPPPQAPP--VLAAPLLQVPPS-PPASPTLQAPRRP---PTPGPDTSVSGP---RL 603 Query: 305 TFGSQPGPPQPLPPKRLDPDAIPSP 329 T PGPP PP R + P Sbjct: 604 TLALAPGPPP--PPSRSPSSTLSGP 626 Score = 61.2 bits (147), Expect = 5e-09 Identities = 94/388 (24%), Positives = 130/388 (33%), Gaps = 87/388 (22%) Query: 12 PFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGP-------VPGYQQTP-PQGMSRAP 63 P + +P G Q S+A + A +GP P + P P+G+ Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281 Query: 64 PSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPG--SQPFGS--------- 112 P PP A G + PS+ +Q Q P + P S Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPS----PSAALQSQAPPTLPATPHSSSLTCQLATP 337 Query: 113 -PLAPVG-NQPPVLQPYGPPPTS--AQVATQLSG--MQISGAVAPAPPSSGLGFGPPTS- 165 PLAP + PP LQ PP + +Q T L +Q + + P+PP S L PP + Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397 Query: 166 ----------------------LASASGSFPNS----------------GLYGSYPQGQA 187 LA+ S PN+ + + + Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457 Query: 188 PPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHV 247 PP+S + P P +AP +PPAS P M+ P P + P + Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPAS-----PPMSPSATPPPQAPPPLAAPPLQL 512 Query: 248 SSPPQALPPGTQMTGPLG--PLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPT 305 + PP PP T PL P PP P Q + P A P S P P AP Sbjct: 513 AKPPPQAPPALA-TPPLQALPSPPASFPGQAPFSPS-------ASLPMSPLATPPPQAPP 564 Query: 306 FGSQP----GPPQPLPPKRLDPDAIPSP 329 + P P P P P P+P Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTP 592 Score = 47.4 bits (111), Expect = 8e-05 Identities = 65/274 (23%), Positives = 95/274 (34%), Gaps = 61/274 (22%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG 67 PP+ P P P P AP + P TPP +PP+S Sbjct: 489 PPMSPSATPPPQAP----------PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 538 Query: 68 APPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPV---- 123 P +P Q P + ++P S P SP +PP Sbjct: 539 --PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP-ASPTLQAPRRPPTPGPD 595 Query: 124 -----------LQPYGPPPTSAQVATQLSGMQISG--AVAPAPPSSGLGFGPPTSLASAS 170 L P PPP S ++ LSG ++G + A + P G+ +A+ Sbjct: 596 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655 Query: 171 GSFPNSGLYGSYP----QGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSM 226 P++ L +P +G APPL+ +G PG P PPA+G Sbjct: 656 SPPPDAELAACHPAAWSRGPAPPLA-FRGAPGAPLP-----------WPPATG------- 696 Query: 227 TGPLLPGQSFGGPSVSQ---PNHVSSPPQALPPG 257 PG + G ++ + P + P AL PG Sbjct: 697 -----PGSADGLCTIYETEGPESATPAPGALDPG 725 Score = 32.7 bits (73), Expect = 1.9 Identities = 59/238 (24%), Positives = 84/238 (35%), Gaps = 61/238 (25%) Query: 122 PVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGS 181 P P PPP + L +GAV P LA +G + + S Sbjct: 29 PPGSPRPPPPVTPAALRVLGA---AGAVGRKP------------LAERAGGIGGATIPES 73 Query: 182 YPQGQAPPLSQAQGHPGIQTPQRSA--PSQASSFTPPASG-GPRLPSMTGPLLPGQSFGG 238 P+ P RSA S+ + PPASG G R P P ++ Sbjct: 74 APRA---------------GPTRSAGTSSRNPASRPPASGRGERAP-------PAKN--- 108 Query: 239 PSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQP---GYQPQQNGSFGPARGPQSN 295 + P VSSP +A GT GPLG S ++ G + + G + + Sbjct: 109 ---TSPGPVSSPGRA--SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 163 Query: 296 YGGPYPAAPT---------FGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEP 344 GP P P+ G++ G P+P P R P P + + + TEP Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT-EGPRKSVSSASEHSTTEP 220 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 74.3 bits (181), Expect = 6e-13 Identities = 86/325 (26%), Positives = 119/325 (36%), Gaps = 46/325 (14%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG 67 P PP Q P P S GS + P TPP +APP+ Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP---QAPPALA 362 Query: 68 APPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQP--PVLQ 125 PP +P Q + V + + P S P P+ + P P + Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422 Query: 126 PYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQG 185 P PP+ A + +Q V P+PP+S PP S ++ P Sbjct: 423 PSATPPSQAPPSLAAPPLQ----VPPSPPAS-----PPMSPSAT-------------PPP 460 Query: 186 QAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQP- 244 QAPP A + P ++ P+ A TPP P P+ PGQ+ PS S P Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALA---TPPLQALPSPPAS----FPGQAPFSPSASLPM 513 Query: 245 NHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAP 304 + +++PP PP + PL +PP P P Q + P GP ++ GP Sbjct: 514 SPLATPPPQAPP--VLAAPLLQVPPS-PPASPTLQAPRRP---PTPGPDTSVSGP---RL 564 Query: 305 TFGSQPGPPQPLPPKRLDPDAIPSP 329 T PGPP PP R + P Sbjct: 565 TLALAPGPPP--PPSRSPSSTLSGP 587 Score = 67.4 bits (163), Expect = 7e-11 Identities = 92/378 (24%), Positives = 131/378 (34%), Gaps = 42/378 (11%) Query: 47 PVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPG 106 P P + PP R SS + ++T +P + G +Q S ++ P Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS--AGGGLQRPASRSLSSSATPL 240 Query: 107 SQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSL 166 S P S + G P P P Q L Q++ A P+ G P L Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQA---LRPPQVTPPRKDAAPALGPLSSSP--L 295 Query: 167 ASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSM 226 A+ S S P P APP Q + +P + PSQA++ + G P L + Sbjct: 296 ATPSPSAP--------PSPSAPPSLQT-----LPSPPATPPSQATT----SLGSPTLQAT 338 Query: 227 TG--PLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQ-- 282 P P P P ++ PP PP + PL PL SPQ P Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLL 397 Query: 283 NGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGT 342 F P P PA+P P P PP + P P+QV + Sbjct: 398 QAPFSPPPSPPVQAPFSPPASP-----PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452 Query: 343 EPFVTGVRGQVPPLVTTNF-LVKDQGNASP-------RYIRCTSYNIPCTSDMAKQAQVP 394 P T PPL L K A P + + + P + + A +P Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512 Query: 395 LAAVIKPLARLPPEEASP 412 ++ + P + PP A+P Sbjct: 513 MSPLATPPPQAPPVLAAP 530 Score = 65.5 bits (158), Expect = 3e-10 Identities = 85/354 (24%), Positives = 118/354 (33%), Gaps = 49/354 (13%) Query: 12 PFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGP-------VPGYQQTP-PQGMSRAP 63 P + +P G Q S+A + A +GP P + P P+G+ Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 272 Query: 64 PSSGAPPASTAQAPCGQAAYGQFG--QGDVQNGPSSTVQMQRLPG---------SQPFGS 112 P PP A G + PS+ +Q LP + GS Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332 Query: 113 PLAPVGNQ---PPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTS---- 165 P + P L P PP A A L +Q + +PP S L P + Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392 Query: 166 ----LASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGP 221 L + P+ + + +PP+S + P P +AP +PPAS Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS--- 449 Query: 222 RLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLG--PLPPMHSPQQPGYQ 279 P M+ P P + P ++ PP PP T PL P PP P Q + Sbjct: 450 --PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA-TPPLQALPSPPASFPGQAPFS 506 Query: 280 PQQNGSFGPARGPQSNYGGPYPAAPTFGSQP----GPPQPLPPKRLDPDAIPSP 329 P A P S P P AP + P P P P P P+P Sbjct: 507 PS-------ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553 Score = 47.4 bits (111), Expect = 8e-05 Identities = 65/274 (23%), Positives = 95/274 (34%), Gaps = 61/274 (22%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG 67 PP+ P P P P AP + P TPP +PP+S Sbjct: 450 PPMSPSATPPPQAP----------PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 499 Query: 68 APPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPV---- 123 P +P Q P + ++P S P SP +PP Sbjct: 500 --PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP-ASPTLQAPRRPPTPGPD 556 Query: 124 -----------LQPYGPPPTSAQVATQLSGMQISG--AVAPAPPSSGLGFGPPTSLASAS 170 L P PPP S ++ LSG ++G + A + P G+ +A+ Sbjct: 557 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 616 Query: 171 GSFPNSGLYGSYP----QGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSM 226 P++ L +P +G APPL+ +G PG P PPA+G Sbjct: 617 SPPPDAELAACHPAAWSRGPAPPLA-FRGAPGAPLP-----------WPPATG------- 657 Query: 227 TGPLLPGQSFGGPSVSQ---PNHVSSPPQALPPG 257 PG + G ++ + P + P AL PG Sbjct: 658 -----PGSADGLCTIYETEGPESATPAPGALDPG 686 Score = 36.6 bits (83), Expect = 0.13 Identities = 99/439 (22%), Positives = 138/439 (31%), Gaps = 131/439 (29%) Query: 94 GPSSTVQMQRLPG---SQPFGSPLAPVGNQPPVLQPYGPP-------------------- 130 G ++ R PG +P GSP P P L+ G Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 Query: 131 PTSAQVA--TQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGS-----FPNSGL----- 178 P SA A T+ S SG APP+ GP +S ASG+ GL Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130 Query: 179 -------------------------YGSYPQGQAPPLSQ-----------------AQGH 196 G P +P +++ A+ Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190 Query: 197 PGIQTPQRSA----------PSQASSFTPPASGGPRLPS----------MTGPLLPGQSF 236 P + P++S PS A+ P A GG + P+ ++ P G S Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250 Query: 237 GG-------PSVSQPNHVSS--PPQALPPGTQMTGPLGPL-------PPMHSPQQPGYQP 280 G PS +P + + PPQ PP LGPL P +P P P Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 Query: 281 QQNGSFGPARGPQS----NYGGPYPAAPTFGSQPGPP-QPL--PPKRLDPDAIPSPIQVI 333 P P S + G P A T P PP PL PP + P P+Q Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQA-THSFLPSPPLSPLATPPPQAPPALALPPLQAP 369 Query: 334 EDDRNNRGTEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYNIPCTSDMAKQAQV 393 + P T Q P + + L Q SP + P + + A Sbjct: 370 PSPPASPPLSPLAT-PSPQAPNALAVHLL---QAPFSP------PPSPPVQAPFSPPASP 419 Query: 394 PLAAVIKPLARLPPEEASP 412 P++ P ++ PP A+P Sbjct: 420 PVSPSATPPSQAPPSLAAP 438 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 74.3 bits (181), Expect = 6e-13 Identities = 96/309 (31%), Positives = 109/309 (35%), Gaps = 35/309 (11%) Query: 34 STAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCG--QAAYGQFGQGDV 91 S P P GP P PPQG A + P A TA P Q A Q Sbjct: 199 SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 258 Query: 92 Q----NGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPP-PTSAQVATQLSGMQIS 146 PS +Q L GS G P AP QPP L GPP P S Q L Q Sbjct: 259 SPHPPPHPSPHPPLQPLTGSA--GQPSAPSHAQPP-LHGQGPPGPHSLQAGPLL---QHP 312 Query: 147 GAVAP--APPSSG-----LGFGPPTSLASASGSFP--NSGLYGSYPQGQAP----PLSQA 193 G P PP + LG P + S P S L P + P PL+ Sbjct: 313 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 372 Query: 194 QGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQA 253 P TP P+ + PP GP SM L P + S +H PP A Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH---PPSA 429 Query: 254 LPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQP--- 310 PP Q+ PLP + Q PG QN PA P + P P F P Sbjct: 430 HPPPLQLMPQSQPLPSSPA-QPPGLTQSQNLPPPPASHPPTGLHQVAP-QPPFAQHPFVP 487 Query: 311 -GPPQPLPP 318 GPP PP Sbjct: 488 GGPPPITPP 496 Score = 49.7 bits (117), Expect = 2e-05 Identities = 61/201 (30%), Positives = 72/201 (35%), Gaps = 16/201 (7%) Query: 139 QLSGMQISGAVAPAPPSSGLG---FGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQG 195 Q +Q V PAP S+ G P SA+ P GS QAP QA Sbjct: 183 QPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ----GSPTASQAPNQPQAPT 238 Query: 196 HPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQAL- 254 P T + AP+ PP+ P PS PL P G S P+H P Sbjct: 239 APVPHTHIQQAPALHPQ-RPPSPHPPPHPSPHPPLQPLTGSAGQP-SAPSHAQPPLHGQG 296 Query: 255 PPGTQ--MTGPL----GPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGS 308 PPG GPL GP P P Q G+ A P ++ P + Sbjct: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356 Query: 309 QPGPPQPLPPKRLDPDAIPSP 329 QP QPLPP L I P Sbjct: 357 QPPREQPLPPAPLAMPHIKPP 377 Score = 36.2 bits (82), Expect = 0.17 Identities = 61/224 (27%), Positives = 73/224 (32%), Gaps = 45/224 (20%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG 67 PP P Q H G S + A N P P + + PPS+ Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA------NLPPPPALKPLSSLSTHHPPSAH 430 Query: 68 APPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSP--LAPVGNQPPVLQ 125 PP P Q Q P Q Q LP P L V QPP Q Sbjct: 431 PPPLQLM--PQSQPLPSSPAQ------PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 482 Query: 126 ----PYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGS 181 P GPPP + S + PA P G PP S A+ASG GS Sbjct: 483 HPFVPGGPPPITPPTCP-------STSTPPAGP--GTSAQPPCSGAAASG--------GS 525 Query: 182 YPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPS 225 G + PL P +Q + + +PP PR PS Sbjct: 526 IAGGSSCPL------PTVQIKEEALDDAEEPESPPPP--PRSPS 561 Score = 33.5 bits (75), Expect = 1.1 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 20/109 (18%) Query: 239 PSVSQPNHVSSPPQALPPGTQMTGPLGP------LPPMHSP--QQPGYQPQ--------Q 282 P++ P V+ P + PPGT GP +PP SP Q QPQ Sbjct: 185 PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 244 Query: 283 NGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQ 331 + PA PQ P P P S P QPL P A PS Q Sbjct: 245 HIQQAPALHPQR---PPSPHPPPHPSPHPPLQPLTGSAGQPSA-PSHAQ 289 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 74.3 bits (181), Expect = 6e-13 Identities = 96/309 (31%), Positives = 109/309 (35%), Gaps = 35/309 (11%) Query: 34 STAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCG--QAAYGQFGQGDV 91 S P P GP P PPQG A + P A TA P Q A Q Sbjct: 753 SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812 Query: 92 Q----NGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPP-PTSAQVATQLSGMQIS 146 PS +Q L GS G P AP QPP L GPP P S Q L Q Sbjct: 813 SPHPPPHPSPHPPLQPLTGSA--GQPSAPSHAQPP-LHGQGPPGPHSLQAGPLL---QHP 866 Query: 147 GAVAP--APPSSG-----LGFGPPTSLASASGSFP--NSGLYGSYPQGQAP----PLSQA 193 G P PP + LG P + S P S L P + P PL+ Sbjct: 867 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926 Query: 194 QGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQA 253 P TP P+ + PP GP SM L P + S +H PP A Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH---PPSA 983 Query: 254 LPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQP--- 310 PP Q+ PLP + Q PG QN PA P + P P F P Sbjct: 984 HPPPLQLMPQSQPLPSSPA-QPPGLTQSQNLPPPPASHPPTGLHQVAP-QPPFAQHPFVP 1041 Query: 311 -GPPQPLPP 318 GPP PP Sbjct: 1042 GGPPPITPP 1050 Score = 49.7 bits (117), Expect = 2e-05 Identities = 61/201 (30%), Positives = 72/201 (35%), Gaps = 16/201 (7%) Query: 139 QLSGMQISGAVAPAPPSSGLG---FGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQG 195 Q +Q V PAP S+ G P SA+ P GS QAP QA Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ----GSPTASQAPNQPQAPT 792 Query: 196 HPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQAL- 254 P T + AP+ PP+ P PS PL P G S P+H P Sbjct: 793 APVPHTHIQQAPALHPQ-RPPSPHPPPHPSPHPPLQPLTGSAGQP-SAPSHAQPPLHGQG 850 Query: 255 PPGTQ--MTGPL----GPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGS 308 PPG GPL GP P P Q G+ A P ++ P + Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910 Query: 309 QPGPPQPLPPKRLDPDAIPSP 329 QP QPLPP L I P Sbjct: 911 QPPREQPLPPAPLAMPHIKPP 931 Score = 36.2 bits (82), Expect = 0.17 Identities = 61/224 (27%), Positives = 73/224 (32%), Gaps = 45/224 (20%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG 67 PP P Q H G S + A N P P + + PPS+ Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA------NLPPPPALKPLSSLSTHHPPSAH 984 Query: 68 APPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSP--LAPVGNQPPVLQ 125 PP P Q Q P Q Q LP P L V QPP Q Sbjct: 985 PPPLQLM--PQSQPLPSSPAQ------PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036 Query: 126 ----PYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGS 181 P GPPP + S + PA P G PP S A+ASG GS Sbjct: 1037 HPFVPGGPPPITPPTCP-------STSTPPAGP--GTSAQPPCSGAAASG--------GS 1079 Query: 182 YPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPS 225 G + PL P +Q + + +PP PR PS Sbjct: 1080 IAGGSSCPL------PTVQIKEEALDDAEEPESPPPP--PRSPS 1115 Score = 33.5 bits (75), Expect = 1.1 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 20/109 (18%) Query: 239 PSVSQPNHVSSPPQALPPGTQMTGPLGP------LPPMHSP--QQPGYQPQ--------Q 282 P++ P V+ P + PPGT GP +PP SP Q QPQ Sbjct: 739 PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798 Query: 283 NGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQ 331 + PA PQ P P P S P QPL P A PS Q Sbjct: 799 HIQQAPALHPQR---PPSPHPPPHPSPHPPLQPLTGSAGQPSA-PSHAQ 843 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 74.3 bits (181), Expect = 6e-13 Identities = 96/309 (31%), Positives = 109/309 (35%), Gaps = 35/309 (11%) Query: 34 STAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCG--QAAYGQFGQGDV 91 S P P GP P PPQG A + P A TA P Q A Q Sbjct: 753 SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812 Query: 92 Q----NGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPP-PTSAQVATQLSGMQIS 146 PS +Q L GS G P AP QPP L GPP P S Q L Q Sbjct: 813 SPHPPPHPSPHPPLQPLTGSA--GQPSAPSHAQPP-LHGQGPPGPHSLQAGPLL---QHP 866 Query: 147 GAVAP--APPSSG-----LGFGPPTSLASASGSFP--NSGLYGSYPQGQAP----PLSQA 193 G P PP + LG P + S P S L P + P PL+ Sbjct: 867 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926 Query: 194 QGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQA 253 P TP P+ + PP GP SM L P + S +H PP A Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHH---PPSA 983 Query: 254 LPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQP--- 310 PP Q+ PLP + Q PG QN PA P + P P F P Sbjct: 984 HPPPLQLMPQSQPLPSSPA-QPPGLTQSQNLPPPPASHPPTGLHQVAP-QPPFAQHPFVP 1041 Query: 311 -GPPQPLPP 318 GPP PP Sbjct: 1042 GGPPPITPP 1050 Score = 49.7 bits (117), Expect = 2e-05 Identities = 61/201 (30%), Positives = 72/201 (35%), Gaps = 16/201 (7%) Query: 139 QLSGMQISGAVAPAPPSSGLG---FGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQG 195 Q +Q V PAP S+ G P SA+ P GS QAP QA Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ----GSPTASQAPNQPQAPT 792 Query: 196 HPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQAL- 254 P T + AP+ PP+ P PS PL P G S P+H P Sbjct: 793 APVPHTHIQQAPALHPQ-RPPSPHPPPHPSPHPPLQPLTGSAGQP-SAPSHAQPPLHGQG 850 Query: 255 PPGTQ--MTGPL----GPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGS 308 PPG GPL GP P P Q G+ A P ++ P + Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910 Query: 309 QPGPPQPLPPKRLDPDAIPSP 329 QP QPLPP L I P Sbjct: 911 QPPREQPLPPAPLAMPHIKPP 931 Score = 36.2 bits (82), Expect = 0.17 Identities = 61/224 (27%), Positives = 73/224 (32%), Gaps = 45/224 (20%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG 67 PP P Q H G S + A N P P + + PPS+ Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNA------NLPPPPALKPLSSLSTHHPPSAH 984 Query: 68 APPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSP--LAPVGNQPPVLQ 125 PP P Q Q P Q Q LP P L V QPP Q Sbjct: 985 PPPLQLM--PQSQPLPSSPAQ------PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036 Query: 126 ----PYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGS 181 P GPPP + S + PA P G PP S A+ASG GS Sbjct: 1037 HPFVPGGPPPITPPTCP-------STSTPPAGP--GTSAQPPCSGAAASG--------GS 1079 Query: 182 YPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPS 225 G + PL P +Q + + +PP PR PS Sbjct: 1080 IAGGSSCPL------PTVQIKEEALDDAEEPESPPPP--PRSPS 1115 Score = 33.5 bits (75), Expect = 1.1 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 20/109 (18%) Query: 239 PSVSQPNHVSSPPQALPPGTQMTGPLGP------LPPMHSP--QQPGYQPQ--------Q 282 P++ P V+ P + PPGT GP +PP SP Q QPQ Sbjct: 739 PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798 Query: 283 NGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQ 331 + PA PQ P P P S P QPL P A PS Q Sbjct: 799 HIQQAPALHPQR---PPSPHPPPHPSPHPPLQPLTGSAGQPSA-PSHAQ 843 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 70.5 bits (171), Expect = 8e-12 Identities = 107/407 (26%), Positives = 133/407 (32%), Gaps = 77/407 (18%) Query: 9 PVPPFGQPQPI----YPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQ------- 57 P P G P P PGY G+ G P P VPG P + Sbjct: 67 PAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPK 126 Query: 58 ---GMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPL 114 G + P G P P G + G+ GQ GP+ + PG + G+P Sbjct: 127 GDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQ----QGPTGAPGPRGFPGEK--GAPG 180 Query: 115 APVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFP 174 P N YG P + L G Q G P+ P G+G + G Sbjct: 181 VPGMNGQKGEMGYGAPGRPGERG--LPGPQ--GPTGPSGPP-GVGKRGENGVPGQPGIKG 235 Query: 175 NSGLYGSY-----PQGQAPP------------LSQAQGHPGIQTPQR--SAPSQASSFTP 215 + G G P Q PP + A G PGI + AP A P Sbjct: 236 DRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGP 295 Query: 216 PASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQ 275 P G P LP + G P GGP P LP +TGP G + P Sbjct: 296 PGFGKPGLPGLKGERGPAGLPGGPGAKG----EQGPAGLPGKPGLTGPPGNMGPQGPKGI 351 Query: 276 PGYQ--PQQNGSFGPA-----------RGPQSNYGGP-YPAAPTFGSQPGPPQPLPPKRL 321 PG P G GPA RG + G P YP P G P LP + Sbjct: 352 PGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNP-GLPGPKG 410 Query: 322 D-----PDAIPSPIQVI--------EDDRNNRGTEPFVTGVRGQVPP 355 D P +P P+ + RG P + G RG + P Sbjct: 411 DPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGA-PGIPGTRGPIGP 456 Score = 54.7 bits (130), Expect = 5e-07 Identities = 84/317 (26%), Positives = 109/317 (34%), Gaps = 70/317 (22%) Query: 28 YGGQSGSTAPAIPYG--AYNGPV----PGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQA 81 + G+ G P P G GP PG P G P + G P A P G Sbjct: 239 FPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAP--GQPGIPGTKGLPGAPGIAGPPGPP 296 Query: 82 AYGQFGQGDV--QNGPSSTVQMQRLPGSQ-PFGSPLAPVGNQPPV-LQPYGPPPTSAQVA 137 +G+ G + + GP+ G Q P G P P PP + P GP Sbjct: 297 GFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKG------ 350 Query: 138 TQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHP 197 I G+ P G P A G + G G P L +G+P Sbjct: 351 -------IPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNP 403 Query: 198 GIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALP-- 255 G+ P+ P GGP P + GP+ P + G P ++ + P+ P Sbjct: 404 GLPGPKGD----------PGVGGP--PGLPGPVGPAGAKGMPG----HNGEAGPRGAPGI 447 Query: 256 PGTQMTGPLGPLPPMHSPQQPGY-----QPQQNGSFGPA-------RGPQSNYGGP---- 299 PGT+ GP+GP P PG+ P G GPA GP G P Sbjct: 448 PGTR--GPIGP------PGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRG 499 Query: 300 ---YPAAPTFGSQPGPP 313 P P PGPP Sbjct: 500 HSGEPGLPGPPGPPGPP 516 Score = 32.3 bits (72), Expect = 2.5 Identities = 26/77 (33%), Positives = 30/77 (38%), Gaps = 5/77 (6%) Query: 255 PPGTQMTGPLGPLPPMHSPQQPGY-QPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPP 313 PPG GP G P P +PGY P G G GP P P +PG Sbjct: 64 PPGP--AGPRGHPGPSGPPGKPGYGSPGLQGEPG-LPGPPGPSAVGKPGVPGLPGKPGER 120 Query: 314 QPLPPK-RLDPDAIPSP 329 P PK + P +P P Sbjct: 121 GPYGPKGDVGPAGLPGP 137 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 70.5 bits (171), Expect = 8e-12 Identities = 104/355 (29%), Positives = 127/355 (35%), Gaps = 67/355 (18%) Query: 9 PVPPFGQPQPI-YP----GYHQSSYGGQSGSTAPAIPYG-------AYNGPVPGYQQTPP 56 P P+G P YP G QS+ GG S T PYG G P Y Q P Sbjct: 418 PGQPYGSQTPQRYPMTMQGRAQSAMGGLS-YTQQIPPYGQQGPSGYGQQGQTPYYNQQSP 476 Query: 57 QGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAP 116 + PP S PP+ T P Q +Y Q Q SS + P P AP Sbjct: 477 HPQQQQPPYSQQPPSQT---PHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP 533 Query: 117 VGNQ-----------PPVLQPYGPPPTSAQVATQLSGMQISGAVA-PAPPS--------S 156 +Q PP QP P Q Q + +S A P P S S Sbjct: 534 YPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYS 593 Query: 157 GLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPP 216 F PP L+ S +GS AP ++ ++G G + S S+ SS Sbjct: 594 QQRFPPPQELSQDS--------FGSQASS-APSMTSSKG--GQEDMNLSLQSRPSSLPDL 642 Query: 217 ASGGPRLPSMT-GPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQ 275 + LP T G L PG S G S SQ S+P Q+ P P SP Sbjct: 643 SGSIDDLPMGTEGALSPGVSTSGISSSQGEQ-SNPAQS------------PFSPHTSPHL 689 Query: 276 PGYQ-PQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSP 329 PG + P + PA QS G PAA PG P P D+I P Sbjct: 690 PGIRGPSPSPVGSPASVAQSRSGPLSPAA-----VPGNQMPPRPPSGQSDSIMHP 739 Score = 68.2 bits (165), Expect = 4e-11 Identities = 96/380 (25%), Positives = 119/380 (31%), Gaps = 74/380 (19%) Query: 20 YPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRA----PPSSGAPPASTAQ 75 +P + +SY + P P A + P G TP G + A PP S + AS++ Sbjct: 207 FPNHQYNSYYPNRSAYPPPAPAYALSSPRGG---TPGSGAAAAAGSKPPPSSSASASSSS 263 Query: 76 APCGQAAYGQFGQG-------------------DVQNGPSSTVQMQRLPGSQPFGSPL-- 114 + Q +G G G + PSS Q PG G P Sbjct: 264 SSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDG 323 Query: 115 -APVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLA-SASGS 172 A G Q +G +A A G Q AP P S G G P + S Sbjct: 324 GAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSP 383 Query: 173 FPNSGLYGSYPQGQAPPLSQAQGHP--------------GIQTPQRSAPSQASSFTPPAS 218 G P G P SQ QG P G QTPQR P A Sbjct: 384 MDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY-PMTMQGRAQSAM 442 Query: 219 GG----PRLP--SMTGPLLPGQS---------FGGPSVSQPNHVSSPP------------ 251 GG ++P GP GQ P QP + PP Sbjct: 443 GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502 Query: 252 --QALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQ 309 Q+ PP Q + P P P Q P + + PQS P A + Q Sbjct: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQ 562 Query: 310 PGPPQPLPPKRLDPDAIPSP 329 P QP P A P P Sbjct: 563 QQPQQPAPSTLSQQAAYPQP 582 Score = 57.4 bits (137), Expect = 7e-08 Identities = 101/357 (28%), Positives = 128/357 (35%), Gaps = 68/357 (19%) Query: 2 NVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNG-PVPGYQQTPPQGMS 60 N N + P P PG GG S A P+ A P P Y P G S Sbjct: 102 NSNGNAGPRPALNNNLTEPPG----GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRS 157 Query: 61 RAPPSSGAPPASTAQAPCGQAAYGQFGQG--DVQNGPSSTVQMQRLP--GSQPFGSPLAP 116 PS+ A+ A A Q GQ G +Q+G ++ P S G P Sbjct: 158 ---PSA---VAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQ 211 Query: 117 VGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVA-----PAPPSSGLGFGPPTSLA---- 167 + P Y PP + +++ G SGA A P P SS +S A Sbjct: 212 YNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRF 271 Query: 168 SASGSFPNSGLYGSYPQGQAPPL--------SQAQGHPGIQTPQRSAPSQ---------- 209 A G S G PQ A P S A+G+ G S Q Sbjct: 272 GAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPAD 331 Query: 210 ----------ASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQ 259 A++ ASGG + S P+ PG S GG QP ++ PQ P Q Sbjct: 332 MASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGG---GQP--LARTPQPSSPMDQ 386 Query: 260 MTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPL 316 M G + P P + P Y QQ GP GPQ +G YP P +GSQ P+ Sbjct: 387 M-GKMRPQP--YGGTNP-YSQQQ----GPPSGPQQGHG--YPGQP-YGSQTPQRYPM 432 Score = 45.1 bits (105), Expect = 4e-04 Identities = 77/321 (23%), Positives = 100/321 (31%), Gaps = 64/321 (19%) Query: 12 PFGQPQPIYPGYHQSSYGGQSG--STAPAIPYGAYNGP-VPGYQQTPPQGMSRAPPSSGA 68 P G + PG S G S P+ + P +PG + G S +P S A Sbjct: 650 PMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIR-----GPSPSPVGSPA 704 Query: 69 PPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYG 128 A + P AA P + QM P S S + P NQ + Q G Sbjct: 705 SVAQSRSGPLSPAAV-----------PGN--QMPPRPPSGQSDSIMHPSMNQSSIAQDRG 751 Query: 129 -------------PPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPN 175 P P SA Q SG QI + +S +GP G +P Sbjct: 752 YMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPR 811 Query: 176 SGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGG-----PRLPSMTGPL 230 Y + P P A G P +GG P +P G L Sbjct: 812 QPNYNALPNANYPSAGMAGG-----------------INPMGAGGQMHGQPGIPPY-GTL 853 Query: 231 LPGQ---SFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNG-SF 286 PG+ + G PN + PPQ G+ M P G + N Sbjct: 854 PPGRMSHASMGNRPYGPNMANMPPQV---GSGMCPPPGGMNRKTQETAVAMHVAANSIQN 910 Query: 287 GPARGPQSNYGGPYPAAPTFG 307 P P N GG P +G Sbjct: 911 RPPGYPNMNQGGMMGTGPPYG 931 Score = 39.3 bits (90), Expect = 0.021 Identities = 80/336 (23%), Positives = 106/336 (31%), Gaps = 67/336 (19%) Query: 37 PAIPYGAYNGPVPGYQQTPPQGMSRA----PPSSGAPPASTAQAPCGQAAYGQFGQGDVQ 92 P P G+ + P Q+ M+ PP+ + P S G + G D Sbjct: 1132 PPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAF 1191 Query: 93 N-GPSSTVQ----MQRLPGSQPFGSPLAPVGNQP--PVLQPYGPPPTSAQVATQLSGMQI 145 N G ST Q M PG QP + +G P PYG Sbjct: 1192 NDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYG----------------- 1234 Query: 146 SGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRS 205 ++ AP S +SG PN G+ Y + P L P P Sbjct: 1235 --SMRKAPGSDPF---------MSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGG 1283 Query: 206 APSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPP--------- 256 + T P GP TG P P + PPQ Sbjct: 1284 PYDRVR--TEPGI-GPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYG 1340 Query: 257 ---GTQMTGPLGPLP----PMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQ 309 TQ T P P M+ QQ Y+ +G++GP P + G + P Q Sbjct: 1341 NQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGP---PAKRHEGEMYSVPYSTGQ 1397 Query: 310 PGP-PQPLPPKRLDP-----DAIPSPIQVIEDDRNN 339 P Q LPP + P A PSP Q + + N Sbjct: 1398 GQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGN 1433 Score = 34.7 bits (78), Expect = 0.51 Identities = 88/364 (24%), Positives = 110/364 (30%), Gaps = 79/364 (21%) Query: 7 VPPVPPFGQPQPI-YPGYHQS-------SYGGQSGSTAPAIPYGAYNGPVPGYQQT---- 54 +P P G P YP Q SYG Q + P G+ P P Q T Sbjct: 1310 MPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGT--PSGS---PFPSQQTTMYQQ 1364 Query: 55 PPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPL 114 Q R + PPA + Y GQG Q Q+LP +QP Sbjct: 1365 QQQNYKRPMDGTYGPPAKRHEGEMYSVPYST-GQGQPQQ--------QQLPPAQP----- 1410 Query: 115 APVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFP 174 QP Q P V Q A A A GP G Sbjct: 1411 -----QPASQQQAAQPSPQQDVYNQYGNAY--PATATAATERRPAGGPQNQFPFQFGRDR 1463 Query: 175 NSGLYGSYPQGQAPPLSQAQGHP---GIQTPQRSAPSQASS----------FTPPASGGP 221 S G+ Q PP Q G P + Q+ Q + T A GP Sbjct: 1464 VSAPPGTNAQQNMPP--QMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGP 1521 Query: 222 RLPSM--TGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQ 279 + T +L S P+H + P GP P+PPM P YQ Sbjct: 1522 AYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPY--------GPSAPVPPMTRPPPSNYQ 1573 Query: 280 P--------QQNGSFGPARGPQSNYGGPYPAAPTFGS-----QPGPPQPLPPKRLDPDAI 326 P Q S P P N P +P S + GP P+P + P + Sbjct: 1574 PPPSMQNHIPQVSSPAPLPRPMENRTSP-SKSPFLHSGMKMQKAGP--PVPASHIAPAPV 1630 Query: 327 PSPI 330 P+ Sbjct: 1631 QPPM 1634 Score = 33.9 bits (76), Expect = 0.86 Identities = 48/179 (26%), Positives = 63/179 (35%), Gaps = 28/179 (15%) Query: 159 GFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQA--SSFTPP 216 G PP + +A+ S S P+ Q P + + G QTPQ ++ S A PP Sbjct: 1110 GEDPPPDIFAAADSKK------SQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPP 1163 Query: 217 ASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQP 276 P P LPG S Q MT G P M++ Sbjct: 1164 TPAS--TPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMM 1221 Query: 277 G---YQPQQN--GSFGPA----------RGPQSNYGGPY--PAAPTFGS-QPGPPQPLP 317 G Y+P ++ GS A +GP G PY A P G+ GP Q P Sbjct: 1222 GRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYP 1280 >gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] Length = 2068 Score = 70.5 bits (171), Expect = 8e-12 Identities = 104/355 (29%), Positives = 127/355 (35%), Gaps = 67/355 (18%) Query: 9 PVPPFGQPQPI-YP----GYHQSSYGGQSGSTAPAIPYG-------AYNGPVPGYQQTPP 56 P P+G P YP G QS+ GG S T PYG G P Y Q P Sbjct: 418 PGQPYGSQTPQRYPMTMQGRAQSAMGGLS-YTQQIPPYGQQGPSGYGQQGQTPYYNQQSP 476 Query: 57 QGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAP 116 + PP S PP+ T P Q +Y Q Q SS + P P AP Sbjct: 477 HPQQQQPPYSQQPPSQT---PHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP 533 Query: 117 VGNQ-----------PPVLQPYGPPPTSAQVATQLSGMQISGAVA-PAPPS--------S 156 +Q PP QP P Q Q + +S A P P S S Sbjct: 534 YPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYS 593 Query: 157 GLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPP 216 F PP L+ S +GS AP ++ ++G G + S S+ SS Sbjct: 594 QQRFPPPQELSQDS--------FGSQASS-APSMTSSKG--GQEDMNLSLQSRPSSLPDL 642 Query: 217 ASGGPRLPSMT-GPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQ 275 + LP T G L PG S G S SQ S+P Q+ P P SP Sbjct: 643 SGSIDDLPMGTEGALSPGVSTSGISSSQGEQ-SNPAQS------------PFSPHTSPHL 689 Query: 276 PGYQ-PQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSP 329 PG + P + PA QS G PAA PG P P D+I P Sbjct: 690 PGIRGPSPSPVGSPASVAQSRSGPLSPAA-----VPGNQMPPRPPSGQSDSIMHP 739 Score = 68.2 bits (165), Expect = 4e-11 Identities = 96/380 (25%), Positives = 119/380 (31%), Gaps = 74/380 (19%) Query: 20 YPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRA----PPSSGAPPASTAQ 75 +P + +SY + P P A + P G TP G + A PP S + AS++ Sbjct: 207 FPNHQYNSYYPNRSAYPPPAPAYALSSPRGG---TPGSGAAAAAGSKPPPSSSASASSSS 263 Query: 76 APCGQAAYGQFGQG-------------------DVQNGPSSTVQMQRLPGSQPFGSPL-- 114 + Q +G G G + PSS Q PG G P Sbjct: 264 SSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDG 323 Query: 115 -APVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLA-SASGS 172 A G Q +G +A A G Q AP P S G G P + S Sbjct: 324 GAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSP 383 Query: 173 FPNSGLYGSYPQGQAPPLSQAQGHP--------------GIQTPQRSAPSQASSFTPPAS 218 G P G P SQ QG P G QTPQR P A Sbjct: 384 MDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY-PMTMQGRAQSAM 442 Query: 219 GG----PRLP--SMTGPLLPGQS---------FGGPSVSQPNHVSSPP------------ 251 GG ++P GP GQ P QP + PP Sbjct: 443 GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502 Query: 252 --QALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQ 309 Q+ PP Q + P P P Q P + + PQS P A + Q Sbjct: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQ 562 Query: 310 PGPPQPLPPKRLDPDAIPSP 329 P QP P A P P Sbjct: 563 QQPQQPAPSTLSQQAAYPQP 582 Score = 57.4 bits (137), Expect = 7e-08 Identities = 101/357 (28%), Positives = 128/357 (35%), Gaps = 68/357 (19%) Query: 2 NVNQSVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNG-PVPGYQQTPPQGMS 60 N N + P P PG GG S A P+ A P P Y P G S Sbjct: 102 NSNGNAGPRPALNNNLTEPPG----GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRS 157 Query: 61 RAPPSSGAPPASTAQAPCGQAAYGQFGQG--DVQNGPSSTVQMQRLP--GSQPFGSPLAP 116 PS+ A+ A A Q GQ G +Q+G ++ P S G P Sbjct: 158 ---PSA---VAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQ 211 Query: 117 VGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVA-----PAPPSSGLGFGPPTSLA---- 167 + P Y PP + +++ G SGA A P P SS +S A Sbjct: 212 YNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRF 271 Query: 168 SASGSFPNSGLYGSYPQGQAPPL--------SQAQGHPGIQTPQRSAPSQ---------- 209 A G S G PQ A P S A+G+ G S Q Sbjct: 272 GAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPAD 331 Query: 210 ----------ASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQ 259 A++ ASGG + S P+ PG S GG QP ++ PQ P Q Sbjct: 332 MASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGG---GQP--LARTPQPSSPMDQ 386 Query: 260 MTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPL 316 M G + P P + P Y QQ GP GPQ +G YP P +GSQ P+ Sbjct: 387 M-GKMRPQP--YGGTNP-YSQQQ----GPPSGPQQGHG--YPGQP-YGSQTPQRYPM 432 Score = 45.1 bits (105), Expect = 4e-04 Identities = 77/321 (23%), Positives = 100/321 (31%), Gaps = 64/321 (19%) Query: 12 PFGQPQPIYPGYHQSSYGGQSG--STAPAIPYGAYNGP-VPGYQQTPPQGMSRAPPSSGA 68 P G + PG S G S P+ + P +PG + G S +P S A Sbjct: 650 PMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIR-----GPSPSPVGSPA 704 Query: 69 PPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYG 128 A + P AA P + QM P S S + P NQ + Q G Sbjct: 705 SVAQSRSGPLSPAAV-----------PGN--QMPPRPPSGQSDSIMHPSMNQSSIAQDRG 751 Query: 129 -------------PPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPN 175 P P SA Q SG QI + +S +GP G +P Sbjct: 752 YMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPR 811 Query: 176 SGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGG-----PRLPSMTGPL 230 Y + P P A G P +GG P +P G L Sbjct: 812 QPNYNALPNANYPSAGMAGG-----------------INPMGAGGQMHGQPGIPPY-GTL 853 Query: 231 LPGQ---SFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNG-SF 286 PG+ + G PN + PPQ G+ M P G + N Sbjct: 854 PPGRMSHASMGNRPYGPNMANMPPQV---GSGMCPPPGGMNRKTQETAVAMHVAANSIQN 910 Query: 287 GPARGPQSNYGGPYPAAPTFG 307 P P N GG P +G Sbjct: 911 RPPGYPNMNQGGMMGTGPPYG 931 Score = 39.7 bits (91), Expect = 0.016 Identities = 67/288 (23%), Positives = 99/288 (34%), Gaps = 46/288 (15%) Query: 53 QTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGS 112 + PP + A S + P +P G + G Q+ SS + L P + Sbjct: 1111 EDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQ--GPQTPQSTSSSMAEGGDLKPPTPAST 1168 Query: 113 PLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGS 172 P + + P + + A S Q ++ P P G+ P + + G Sbjct: 1169 PHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNP-----GYQPSMNTSDMMGR 1223 Query: 173 F---PNSGLYGSYPQ--GQAPPLSQAQG-HPGIQTPQRSAPSQASSFTPPASGGPRLPSM 226 PN YGS + G P +S QG + G+ P A GP L ++ Sbjct: 1224 MSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRA------------AGPGLGNV 1271 Query: 227 TGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGP------------LPPMHSPQ 274 +GGP + V + P P G TG P P + PQ Sbjct: 1272 AMGPRQHYPYGGPY----DRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQ 1327 Query: 275 QPGYQPQQNGSFGPARGPQSN-YGGPYPAAPTF----GSQPGPPQPLP 317 Q Q Q++ S+G Q G P+P+ T Q P PLP Sbjct: 1328 QQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLP 1375 >gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo sapiens] Length = 1858 Score = 69.3 bits (168), Expect = 2e-11 Identities = 90/334 (26%), Positives = 117/334 (35%), Gaps = 66/334 (19%) Query: 2 NVNQSVPPVPPFGQPQPIY-----PGYHQSSYGGQSGSTAP----------AIPYGAYNG 46 ++N + PP PP P Y P + +Y GS + A+P Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597 Query: 47 PVPGYQQTPPQGMSR-------------APPSSGAPPASTAQAPCGQAAYGQFGQGDVQN 93 VPG+ TP + PP PPA ++ Q V Sbjct: 1598 TVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVV- 1656 Query: 94 GPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQ------ISG 147 GP V SQ G L P P + PPP +T L G+Q ++ Sbjct: 1657 GPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPP---HPSTGLQGLQAQHQHVVNS 1713 Query: 148 AVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAP 207 A P PP PP S ASG S +P Q PPL + HP + P Sbjct: 1714 APPPPPP-------PPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVP----PYP 1762 Query: 208 SQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQ--PNHVSSPPQ----------ALP 255 SQA+ T G PS TGP P GP + PN + +P ALP Sbjct: 1763 SQATHHTTLGPGPQHQPSGTGPHCP-LPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALP 1821 Query: 256 PGTQMTGPLGPLP---PMHSPQ-QPGYQPQQNGS 285 G Q P+P P+H Q P +Q +GS Sbjct: 1822 HGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGS 1855 Score = 42.4 bits (98), Expect = 0.002 Identities = 75/308 (24%), Positives = 99/308 (32%), Gaps = 73/308 (23%) Query: 105 PGSQPFGSPLAPVGNQ-PPVLQPYGPP-----------PTSAQVAT-------------- 138 P SQ GSP P +Q P V P P P + Q AT Sbjct: 1469 PPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSS 1528 Query: 139 ----QLSGMQISGAVAPAPPSSGLGFGPPTS--------------LASASGSFPNSGLYG 180 Q + ++ P PP PP+S GS ++ Sbjct: 1529 ATYSQFNQQSLNSTAPPPPPPP-----PPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFT 1583 Query: 181 SYPQGQAPPLSQAQGHPGIQ-TPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGP 239 S P P + Q PG TP PSQ + + P P PG Sbjct: 1584 SGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHL--- 1640 Query: 240 SVSQPN--------HVSSPPQALPPG----TQMTGPLGPLPPMHSPQQPGYQPQQNGSFG 287 V QPN HV P A+ PG +Q G P PP P + P + S G Sbjct: 1641 -VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTG 1699 Query: 288 PARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVT 347 +G Q+ + +AP P PP P P L + Q + ++G F + Sbjct: 1700 -LQGLQAQHQHVVNSAP-----PPPPPPPPSSVLASGHHTTSAQALHHP-PHQGPPLFPS 1752 Query: 348 GVRGQVPP 355 VPP Sbjct: 1753 SAHPTVPP 1760 Score = 32.3 bits (72), Expect = 2.5 Identities = 54/232 (23%), Positives = 80/232 (34%), Gaps = 57/232 (24%) Query: 119 NQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGL 178 N P LQ GP P+ +++ M+ P P ++ P TS + Sbjct: 1304 NHIPQLQAKGPVPSFSEL------MEDPDPENPEPTTTNECPSPDTSQNTC--------- 1348 Query: 179 YGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGG 238 ++PP G PG P A + FT P P + ++ G Sbjct: 1349 -------KSPPKMSKPGSPGSVIP---AQAHGKIFTKPD------PQWDSTVSASEAENG 1392 Query: 239 PSVS---QPNHVSSPPQAL----PPGT-------QMTGPLGPLPP-MHSPQQPGYQ---- 279 + Q +S+ QAL PP T Q++ L +P +H P P + Sbjct: 1393 VHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPK 1452 Query: 280 ------PQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDA 325 P Q+G P + P G PY + Q G PQ P + P A Sbjct: 1453 SSTPHTPVQHGYLSP-KPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAA 1503 >gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo sapiens] Length = 1858 Score = 69.3 bits (168), Expect = 2e-11 Identities = 90/334 (26%), Positives = 117/334 (35%), Gaps = 66/334 (19%) Query: 2 NVNQSVPPVPPFGQPQPIY-----PGYHQSSYGGQSGSTAP----------AIPYGAYNG 46 ++N + PP PP P Y P + +Y GS + A+P Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597 Query: 47 PVPGYQQTPPQGMSR-------------APPSSGAPPASTAQAPCGQAAYGQFGQGDVQN 93 VPG+ TP + PP PPA ++ Q V Sbjct: 1598 TVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVV- 1656 Query: 94 GPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQ------ISG 147 GP V SQ G L P P + PPP +T L G+Q ++ Sbjct: 1657 GPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPP---HPSTGLQGLQAQHQHVVNS 1713 Query: 148 AVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAP 207 A P PP PP S ASG S +P Q PPL + HP + P Sbjct: 1714 APPPPPP-------PPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVP----PYP 1762 Query: 208 SQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQ--PNHVSSPPQ----------ALP 255 SQA+ T G PS TGP P GP + PN + +P ALP Sbjct: 1763 SQATHHTTLGPGPQHQPSGTGPHCP-LPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALP 1821 Query: 256 PGTQMTGPLGPLP---PMHSPQ-QPGYQPQQNGS 285 G Q P+P P+H Q P +Q +GS Sbjct: 1822 HGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGS 1855 Score = 42.4 bits (98), Expect = 0.002 Identities = 75/308 (24%), Positives = 99/308 (32%), Gaps = 73/308 (23%) Query: 105 PGSQPFGSPLAPVGNQ-PPVLQPYGPP-----------PTSAQVAT-------------- 138 P SQ GSP P +Q P V P P P + Q AT Sbjct: 1469 PPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSS 1528 Query: 139 ----QLSGMQISGAVAPAPPSSGLGFGPPTS--------------LASASGSFPNSGLYG 180 Q + ++ P PP PP+S GS ++ Sbjct: 1529 ATYSQFNQQSLNSTAPPPPPPP-----PPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFT 1583 Query: 181 SYPQGQAPPLSQAQGHPGIQ-TPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGP 239 S P P + Q PG TP PSQ + + P P PG Sbjct: 1584 SGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHL--- 1640 Query: 240 SVSQPN--------HVSSPPQALPPG----TQMTGPLGPLPPMHSPQQPGYQPQQNGSFG 287 V QPN HV P A+ PG +Q G P PP P + P + S G Sbjct: 1641 -VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTG 1699 Query: 288 PARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVT 347 +G Q+ + +AP P PP P P L + Q + ++G F + Sbjct: 1700 -LQGLQAQHQHVVNSAP-----PPPPPPPPSSVLASGHHTTSAQALHHP-PHQGPPLFPS 1752 Query: 348 GVRGQVPP 355 VPP Sbjct: 1753 SAHPTVPP 1760 Score = 32.3 bits (72), Expect = 2.5 Identities = 54/232 (23%), Positives = 80/232 (34%), Gaps = 57/232 (24%) Query: 119 NQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGL 178 N P LQ GP P+ +++ M+ P P ++ P TS + Sbjct: 1304 NHIPQLQAKGPVPSFSEL------MEDPDPENPEPTTTNECPSPDTSQNTC--------- 1348 Query: 179 YGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGG 238 ++PP G PG P A + FT P P + ++ G Sbjct: 1349 -------KSPPKMSKPGSPGSVIP---AQAHGKIFTKPD------PQWDSTVSASEAENG 1392 Query: 239 PSVS---QPNHVSSPPQAL----PPGT-------QMTGPLGPLPP-MHSPQQPGYQ---- 279 + Q +S+ QAL PP T Q++ L +P +H P P + Sbjct: 1393 VHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPK 1452 Query: 280 ------PQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDA 325 P Q+G P + P G PY + Q G PQ P + P A Sbjct: 1453 SSTPHTPVQHGYLSP-KPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAA 1503 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 68.9 bits (167), Expect = 2e-11 Identities = 96/367 (26%), Positives = 119/367 (32%), Gaps = 71/367 (19%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPS-- 65 PP Q P P H Y G +G P G G P G PP+ Sbjct: 200 PPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTP 259 Query: 66 --------SGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAP- 116 SGAPP P G N P T + P +P + A Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPS--APPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 117 --VGNQP-----PVLQPYGP--------PPTSAQVATQLSGMQISGAVAPAPP------- 154 +G QP P G P +A + + + APAPP Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSS 377 Query: 155 ---SSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQA- 210 SS +S +S++ FP S SYP PP S + + + Q S PSQA Sbjct: 378 SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAV 437 Query: 211 -SSFTPPASGGPRL-------PSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMT- 261 S PP RL P P QS P VS +H Q Q Sbjct: 438 WSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497 Query: 262 -------GPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGS-QPGPP 313 G GP PP P P G S++ PY +P+ GS +P PP Sbjct: 498 QQQQQHHGNSGPPPPGAFPH-------------PLEGGSSHHAHPYAMSPSLGSLRPYPP 544 Query: 314 QP--LPP 318 P LPP Sbjct: 545 GPAHLPP 551 Score = 57.0 bits (136), Expect = 1e-07 Identities = 99/375 (26%), Positives = 127/375 (33%), Gaps = 77/375 (20%) Query: 6 SVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPS 65 S+PP P+ Y SS + S++ + + + P P Q P S PP+ Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS-PFPASQALPSYPHSFPPPT 416 Query: 66 S----GAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQP 121 S PP T + QA + Q GP P P+G LA P Sbjct: 417 SLSVSNQPPKYTQPSLPSQAVWSQ--------GP---------PPPPPYGRLLANSNAHP 459 Query: 122 PVLQPY------GPPPTSA--------------QVATQLSGMQISGAVAPAPPSSGLGFG 161 P PP S Q Q Q G P PP + F Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGA---FP 516 Query: 162 PPTSLASASGSFPNS-----GLYGSYPQGQA---PPLSQAQ-GHPGIQTPQRSAPSQASS 212 P S+ + P + G YP G A PP SQ G P S+ S +SS Sbjct: 517 HPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSS 576 Query: 213 FT---------PPASGGPRLPSMTGPLLPGQSFGGPSVSQ--PNHVSSPP---QALPPGT 258 T P S GP+ P +P + ++S SSP A PPG Sbjct: 577 STSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP 636 Query: 259 QMTGPLGPLPPMH-SPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQ--- 314 G P P + + PGY+P SF G Y G P A +PG P Sbjct: 637 PPYGKRAPSPGAYKTATPPGYKPGSPPSF--RTGTPPGYRGTSPPAGPGTFKPGSPTVGP 694 Query: 315 -PLPPKRLDPDAIPS 328 PLPP P +PS Sbjct: 695 GPLPP--AGPSGLPS 707 Score = 56.6 bits (135), Expect = 1e-07 Identities = 78/351 (22%), Positives = 117/351 (33%), Gaps = 83/351 (23%) Query: 86 FGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPP----------------------- 122 + G V+N S+ + + P PL P QPP Sbjct: 136 YSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYH 195 Query: 123 ----------VLQPYGPPPTSAQVATQLSGMQISG----------AVAPAPPSSGLGFGP 162 P G PP Q+ +G +SG A + P+ G P Sbjct: 196 APMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP 255 Query: 163 PTSLASASGSF---------PNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSF 213 PT+ S S S P + + G PP + P + P P +S Sbjct: 256 PTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASA 315 Query: 214 TPPASGGPRLPS-MTGPLLPGQSFGG--PSVSQPNHVSSPPQALPPGTQMTGPLGPLPPM 270 +PP G LP + P GQ GG P + ++ P +LPP + P PPM Sbjct: 316 SPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS----APAPPM 371 Query: 271 HSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQP---GPPQPL-----PPKRLD 322 P + + + S+ P+PA+ S P PP L PPK Sbjct: 372 RFPYSS--SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQ 429 Query: 323 PDAIPSPI-------------QVIEDDRNNRGTEPFVTGVRGQVPPLVTTN 360 P ++PS +++ + + G P TG + P V+T+ Sbjct: 430 P-SLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTH 479 Score = 56.6 bits (135), Expect = 1e-07 Identities = 75/284 (26%), Positives = 91/284 (32%), Gaps = 65/284 (22%) Query: 25 QSSYGGQSGSTAPAIPYGAYNGPVPG--------YQQTPPQGMSRAPPSSGA--PPASTA 74 Q + G SG P GA+ P+ G Y +P G R P A PP Sbjct: 500 QQQHHGNSGPPPP----GAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP---- 551 Query: 75 QAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSA 134 P Q +Y Q G SS GS P P G Q P+ P PT Sbjct: 552 --PHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPY-PFPPVPTVT 608 Query: 135 QVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQ 194 + LS + + A +PA + GPP P G+ P + Sbjct: 609 TSSATLSTVIATVASSPAGYKTASPPGPP-------------------PYGKRAP---SP 646 Query: 195 GHPGIQTPQRSAPSQASSF---TPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSS-- 249 G TP P SF TPP G P+ G PG GP P S Sbjct: 647 GAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLP 706 Query: 250 ---PPQALP--------------PGTQMTGPLGPLPPMHSPQQP 276 PP A P P + P P+PP SP P Sbjct: 707 SLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP 750 Score = 42.7 bits (99), Expect = 0.002 Identities = 61/235 (25%), Positives = 82/235 (34%), Gaps = 33/235 (14%) Query: 6 SVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYN------GPVPGYQQTPPQGM 59 S+ P PP P + P + Q SY Q+G P + + + G P +P QG Sbjct: 538 SLRPYPP--GPAHLPPPHSQVSYS-QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP 594 Query: 60 SRAP-PSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFG----SPL 114 AP P P +T+ A V + P+ + PG P+G SP Sbjct: 595 QGAPYPFPPVPTVTTSSATLSTVI------ATVASSPAG-YKTASPPGPPPYGKRAPSPG 647 Query: 115 APVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFP 174 A PP +P PP G P +G G P S G P Sbjct: 648 AYKTATPPGYKPGSPPSFRTGTPPGYRG---------TSPPAGPGTFKPGSPTVGPGPLP 698 Query: 175 NSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGP 229 +G G P PP + A G P T + P A + P S P S + P Sbjct: 699 PAGPSG-LPSLPPPPAAPASGPPLSATQIKQEP--AEEYETPESPVPPARSPSPP 750 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 68.9 bits (167), Expect = 2e-11 Identities = 96/367 (26%), Positives = 119/367 (32%), Gaps = 71/367 (19%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPS-- 65 PP Q P P H Y G +G P G G P G PP+ Sbjct: 200 PPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTP 259 Query: 66 --------SGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAP- 116 SGAPP P G N P T + P +P + A Sbjct: 260 ISVSSSGASGAPPTKPPTTPVGGGNLPS--APPPANFPHVTPNLPPPPALRPLNNASASP 317 Query: 117 --VGNQP-----PVLQPYGP--------PPTSAQVATQLSGMQISGAVAPAPP------- 154 +G QP P G P +A + + + APAPP Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSS 377 Query: 155 ---SSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQA- 210 SS +S +S++ FP S SYP PP S + + + Q S PSQA Sbjct: 378 SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAV 437 Query: 211 -SSFTPPASGGPRL-------PSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMT- 261 S PP RL P P QS P VS +H Q Q Sbjct: 438 WSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497 Query: 262 -------GPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGS-QPGPP 313 G GP PP P P G S++ PY +P+ GS +P PP Sbjct: 498 QQQQQHHGNSGPPPPGAFPH-------------PLEGGSSHHAHPYAMSPSLGSLRPYPP 544 Query: 314 QP--LPP 318 P LPP Sbjct: 545 GPAHLPP 551 Score = 57.0 bits (136), Expect = 1e-07 Identities = 99/375 (26%), Positives = 127/375 (33%), Gaps = 77/375 (20%) Query: 6 SVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPS 65 S+PP P+ Y SS + S++ + + + P P Q P S PP+ Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS-PFPASQALPSYPHSFPPPT 416 Query: 66 S----GAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQP 121 S PP T + QA + Q GP P P+G LA P Sbjct: 417 SLSVSNQPPKYTQPSLPSQAVWSQ--------GP---------PPPPPYGRLLANSNAHP 459 Query: 122 PVLQPY------GPPPTSA--------------QVATQLSGMQISGAVAPAPPSSGLGFG 161 P PP S Q Q Q G P PP + F Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGA---FP 516 Query: 162 PPTSLASASGSFPNS-----GLYGSYPQGQA---PPLSQAQ-GHPGIQTPQRSAPSQASS 212 P S+ + P + G YP G A PP SQ G P S+ S +SS Sbjct: 517 HPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSS 576 Query: 213 FT---------PPASGGPRLPSMTGPLLPGQSFGGPSVSQ--PNHVSSPP---QALPPGT 258 T P S GP+ P +P + ++S SSP A PPG Sbjct: 577 STSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP 636 Query: 259 QMTGPLGPLPPMH-SPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQ--- 314 G P P + + PGY+P SF G Y G P A +PG P Sbjct: 637 PPYGKRAPSPGAYKTATPPGYKPGSPPSF--RTGTPPGYRGTSPPAGPGTFKPGSPTVGP 694 Query: 315 -PLPPKRLDPDAIPS 328 PLPP P +PS Sbjct: 695 GPLPP--AGPSGLPS 707 Score = 56.6 bits (135), Expect = 1e-07 Identities = 78/351 (22%), Positives = 117/351 (33%), Gaps = 83/351 (23%) Query: 86 FGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPP----------------------- 122 + G V+N S+ + + P PL P QPP Sbjct: 136 YSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYH 195 Query: 123 ----------VLQPYGPPPTSAQVATQLSGMQISG----------AVAPAPPSSGLGFGP 162 P G PP Q+ +G +SG A + P+ G P Sbjct: 196 APMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPP 255 Query: 163 PTSLASASGSF---------PNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSF 213 PT+ S S S P + + G PP + P + P P +S Sbjct: 256 PTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASA 315 Query: 214 TPPASGGPRLPS-MTGPLLPGQSFGG--PSVSQPNHVSSPPQALPPGTQMTGPLGPLPPM 270 +PP G LP + P GQ GG P + ++ P +LPP + P PPM Sbjct: 316 SPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS----APAPPM 371 Query: 271 HSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQP---GPPQPL-----PPKRLD 322 P + + + S+ P+PA+ S P PP L PPK Sbjct: 372 RFPYSS--SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQ 429 Query: 323 PDAIPSPI-------------QVIEDDRNNRGTEPFVTGVRGQVPPLVTTN 360 P ++PS +++ + + G P TG + P V+T+ Sbjct: 430 P-SLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTH 479 Score = 56.6 bits (135), Expect = 1e-07 Identities = 75/284 (26%), Positives = 91/284 (32%), Gaps = 65/284 (22%) Query: 25 QSSYGGQSGSTAPAIPYGAYNGPVPG--------YQQTPPQGMSRAPPSSGA--PPASTA 74 Q + G SG P GA+ P+ G Y +P G R P A PP Sbjct: 500 QQQHHGNSGPPPP----GAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP---- 551 Query: 75 QAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSA 134 P Q +Y Q G SS GS P P G Q P+ P PT Sbjct: 552 --PHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPY-PFPPVPTVT 608 Query: 135 QVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQ 194 + LS + + A +PA + GPP P G+ P + Sbjct: 609 TSSATLSTVIATVASSPAGYKTASPPGPP-------------------PYGKRAP---SP 646 Query: 195 GHPGIQTPQRSAPSQASSF---TPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSS-- 249 G TP P SF TPP G P+ G PG GP P S Sbjct: 647 GAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLP 706 Query: 250 ---PPQALP--------------PGTQMTGPLGPLPPMHSPQQP 276 PP A P P + P P+PP SP P Sbjct: 707 SLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP 750 Score = 42.7 bits (99), Expect = 0.002 Identities = 61/235 (25%), Positives = 82/235 (34%), Gaps = 33/235 (14%) Query: 6 SVPPVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYN------GPVPGYQQTPPQGM 59 S+ P PP P + P + Q SY Q+G P + + + G P +P QG Sbjct: 538 SLRPYPP--GPAHLPPPHSQVSYS-QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP 594 Query: 60 SRAP-PSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFG----SPL 114 AP P P +T+ A V + P+ + PG P+G SP Sbjct: 595 QGAPYPFPPVPTVTTSSATLSTVI------ATVASSPAG-YKTASPPGPPPYGKRAPSPG 647 Query: 115 APVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFP 174 A PP +P PP G P +G G P S G P Sbjct: 648 AYKTATPPGYKPGSPPSFRTGTPPGYRG---------TSPPAGPGTFKPGSPTVGPGPLP 698 Query: 175 NSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGP 229 +G G P PP + A G P T + P A + P S P S + P Sbjct: 699 PAGPSG-LPSLPPPPAAPASGPPLSATQIKQEP--AEEYETPESPVPPARSPSPP 750 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 68.6 bits (166), Expect = 3e-11 Identities = 81/305 (26%), Positives = 107/305 (35%), Gaps = 58/305 (19%) Query: 64 PSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSS--------TVQMQRLPGSQPFGSPLA 115 PS PP Q G+ Q G Q GP+ T + + PG+ P+ Sbjct: 299 PSPSKPPIQ--QPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK--PPVQ 354 Query: 116 PVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPN 175 P G P QP GP A+ Q +G + + P P + P + P Sbjct: 355 PPGTTKPPAQPLGP----AKPPAQQTGSEKPSSEQPGPKA----LAQPPGVGKTPAQQPG 406 Query: 176 SGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASG---------GPRLPSM 226 + G PL+Q PG+Q+P ++ + P G G Sbjct: 407 PAKPPTQQVGTPKPLAQ---QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463 Query: 227 TGPLLPGQSFGGPSV---SQPNHVSSPPQ--------ALPPGTQMTGPLGPLPPMHSPQQ 275 TGP P GP+ QP PPQ + PG+ P P P SPQQ Sbjct: 464 TGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523 Query: 276 PGYQP---QQNGSFGPARGPQSNYGGPYPAAPTFG------SQPGPPQPLPPKRLDPDAI 326 PG QQ GS P+ P PA P+ SQ G +PL P + P A Sbjct: 524 PGSTKPPSQQPGSAKPSAQQ------PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577 Query: 327 PSPIQ 331 P Q Sbjct: 578 QPPSQ 582 Score = 61.6 bits (148), Expect = 4e-09 Identities = 82/304 (26%), Positives = 105/304 (34%), Gaps = 43/304 (14%) Query: 56 PQGMSRAPPSSGAPPASTAQAPCGQ---------AAYGQFGQGDVQNG---------PSS 97 P+ + PP +G P Q P A+ Q Q D+ G PS Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK 303 Query: 98 TVQMQRLPGSQPFGSP---LAPVGNQPPVLQPYG-PPPTSAQVATQLSGMQISGAVAPAP 153 Q PG P P + G P QP G P + Q T +Q G P Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP-- 361 Query: 154 PSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSF 213 P+ LG P + + S P+S G Q P + + P Q P+Q Sbjct: 362 PAQPLGPAKPPAQQTGSEK-PSSEQPGPKALAQPPGVGKT---PAQQPGPAKPPTQQVGT 417 Query: 214 TPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPG---TQMTGPLGPLPPM 270 P + P L S P ++ V QP P Q PG Q TGP P + Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKT----PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473 Query: 271 HSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQ---PLPPKRLDPDAIP 327 P +P PQQ G PA+ P G P + GS PPQ P P P + Sbjct: 474 PGPAKP--PPQQPG---PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528 Query: 328 SPIQ 331 P Q Sbjct: 529 PPSQ 532 Score = 58.2 bits (139), Expect = 4e-08 Identities = 78/296 (26%), Positives = 104/296 (35%), Gaps = 37/296 (12%) Query: 8 PPVPPFGQPQPIYPGYHQSSYG-GQSGSTAPAIPYGAYNGPV---PGYQQTPPQGMSRAP 63 P PP QP P P Q + Q G P P+ PG + P Q P Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ-----P 355 Query: 64 PSSGAPPAST---AQAPCGQAAYGQFGQGDVQNGPSSTVQ---MQRLPGSQPFGSPLAPV 117 P + PPA A+ P Q G Q GP + Q + + P QP + Sbjct: 356 PGTTKPPAQPLGPAKPPAQQT--GSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA----- 408 Query: 118 GNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSG 177 +PP Q P P + Q Q S A AP P + + P + + G Sbjct: 409 --KPPTQQVGTPKPLAQQPGLQ------SPAKAPGPTKTPVQQPGPGKIPAQQAG---PG 457 Query: 178 LYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGP-RLPSMTGPLLPGQSF 236 + G P SQ G P PQ+ P++ P ++ P + P T P Sbjct: 458 KTSAQQTGPTKPPSQLPG-PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516 Query: 237 GGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGP 292 PS QP S+ P + PG+ P P S QQ Q GS P + P Sbjct: 517 AKPSPQQPG--STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570 Score = 47.0 bits (110), Expect = 1e-04 Identities = 64/232 (27%), Positives = 79/232 (34%), Gaps = 23/232 (9%) Query: 8 PPVPPFGQPQPIYPGYHQSSY---GGQSGSTAPAIPYGAYNGPV--PGYQQTPPQGMSRA 62 PP P G +P P S Q G A A P G P PG + P Q + Sbjct: 361 PPAQPLGPAKP--PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418 Query: 63 PPSSGAPPA-STAQAPCG-QAAYGQFGQGDV---QNGPSSTVQMQRLPGSQPFG------ 111 P + P S A+AP + Q G G + Q GP T Q P P Sbjct: 419 KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAK 478 Query: 112 -SPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASAS 170 P P +PP QP P S Q + Q G P+P G P SA Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538 Query: 171 GSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPR 222 S Q P+SQ +Q P S S+ PP+ G P+ Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPK 586 Score = 38.9 bits (89), Expect = 0.027 Identities = 65/256 (25%), Positives = 89/256 (34%), Gaps = 53/256 (20%) Query: 15 QPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTA 74 QP+ + P S S +T P IP + TPP A PS PP Sbjct: 756 QPKMVKPTTDLVS--SSSATTKPDIPSSKVQSQAEE-KTTPPLKTDSAKPSQSFPPTGEK 812 Query: 75 QAPCGQAAYGQFGQGDV---QNGPSST--------------------VQMQRLPGSQPF- 110 +P A + GPSS +M P ++P Sbjct: 813 VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872 Query: 111 -GSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQIS-GAVAPAPPS---------SGLG 159 GSP P G +P Q P S + Q ++ G++ AP S +G Sbjct: 873 KGSPTPP-GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931 Query: 160 FGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASG 219 FG S+ S + + ++ GQ P SQ+ PG Q APSQ PP S Sbjct: 932 FGFGASIFSQASNLISTA-------GQPGPHSQSG--PGAPMKQAPAPSQ-----PPTSQ 977 Query: 220 GPRLPSMTGPLLPGQS 235 GP + P P +S Sbjct: 978 GPPKSTGQAPPAPAKS 993 Score = 32.0 bits (71), Expect = 3.3 Identities = 40/179 (22%), Positives = 61/179 (34%), Gaps = 31/179 (17%) Query: 96 SSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPP- 154 SS++ + P P P P PP P PP + + ++ V A P Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPL 2455 Query: 155 --------------SSGLGF-----GPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQG 195 S+GL P + S P+ ++ P+ PP++ Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPV 2515 Query: 196 HPGIQT---------PQRSAPSQASSFT--PPASGGPRLPSMTGPLLPGQSFGGPSVSQ 243 P + T P+ + S SS T S +LPS T PL P + P S+ Sbjct: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 68.6 bits (166), Expect = 3e-11 Identities = 81/305 (26%), Positives = 107/305 (35%), Gaps = 58/305 (19%) Query: 64 PSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSS--------TVQMQRLPGSQPFGSPLA 115 PS PP Q G+ Q G Q GP+ T + + PG+ P+ Sbjct: 299 PSPSKPPIQ--QPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK--PPVQ 354 Query: 116 PVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPN 175 P G P QP GP A+ Q +G + + P P + P + P Sbjct: 355 PPGTTKPPAQPLGP----AKPPAQQTGSEKPSSEQPGPKA----LAQPPGVGKTPAQQPG 406 Query: 176 SGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASG---------GPRLPSM 226 + G PL+Q PG+Q+P ++ + P G G Sbjct: 407 PAKPPTQQVGTPKPLAQ---QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463 Query: 227 TGPLLPGQSFGGPSV---SQPNHVSSPPQ--------ALPPGTQMTGPLGPLPPMHSPQQ 275 TGP P GP+ QP PPQ + PG+ P P P SPQQ Sbjct: 464 TGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523 Query: 276 PGYQP---QQNGSFGPARGPQSNYGGPYPAAPTFG------SQPGPPQPLPPKRLDPDAI 326 PG QQ GS P+ P PA P+ SQ G +PL P + P A Sbjct: 524 PGSTKPPSQQPGSAKPSAQQ------PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK 577 Query: 327 PSPIQ 331 P Q Sbjct: 578 QPPSQ 582 Score = 61.6 bits (148), Expect = 4e-09 Identities = 82/304 (26%), Positives = 105/304 (34%), Gaps = 43/304 (14%) Query: 56 PQGMSRAPPSSGAPPASTAQAPCGQ---------AAYGQFGQGDVQNG---------PSS 97 P+ + PP +G P Q P A+ Q Q D+ G PS Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK 303 Query: 98 TVQMQRLPGSQPFGSP---LAPVGNQPPVLQPYG-PPPTSAQVATQLSGMQISGAVAPAP 153 Q PG P P + G P QP G P + Q T +Q G P Sbjct: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP-- 361 Query: 154 PSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSF 213 P+ LG P + + S P+S G Q P + + P Q P+Q Sbjct: 362 PAQPLGPAKPPAQQTGSEK-PSSEQPGPKALAQPPGVGKT---PAQQPGPAKPPTQQVGT 417 Query: 214 TPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPG---TQMTGPLGPLPPM 270 P + P L S P ++ V QP P Q PG Q TGP P + Sbjct: 418 PKPLAQQPGLQSPAKAPGPTKT----PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473 Query: 271 HSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQ---PLPPKRLDPDAIP 327 P +P PQQ G PA+ P G P + GS PPQ P P P + Sbjct: 474 PGPAKP--PPQQPG---PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528 Query: 328 SPIQ 331 P Q Sbjct: 529 PPSQ 532 Score = 58.2 bits (139), Expect = 4e-08 Identities = 78/296 (26%), Positives = 104/296 (35%), Gaps = 37/296 (12%) Query: 8 PPVPPFGQPQPIYPGYHQSSYG-GQSGSTAPAIPYGAYNGPV---PGYQQTPPQGMSRAP 63 P PP QP P P Q + Q G P P+ PG + P Q P Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ-----P 355 Query: 64 PSSGAPPAST---AQAPCGQAAYGQFGQGDVQNGPSSTVQ---MQRLPGSQPFGSPLAPV 117 P + PPA A+ P Q G Q GP + Q + + P QP + Sbjct: 356 PGTTKPPAQPLGPAKPPAQQT--GSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA----- 408 Query: 118 GNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSG 177 +PP Q P P + Q Q S A AP P + + P + + G Sbjct: 409 --KPPTQQVGTPKPLAQQPGLQ------SPAKAPGPTKTPVQQPGPGKIPAQQAG---PG 457 Query: 178 LYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGP-RLPSMTGPLLPGQSF 236 + G P SQ G P PQ+ P++ P ++ P + P T P Sbjct: 458 KTSAQQTGPTKPPSQLPG-PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516 Query: 237 GGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGP 292 PS QP S+ P + PG+ P P S QQ Q GS P + P Sbjct: 517 AKPSPQQPG--STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570 Score = 47.0 bits (110), Expect = 1e-04 Identities = 64/232 (27%), Positives = 79/232 (34%), Gaps = 23/232 (9%) Query: 8 PPVPPFGQPQPIYPGYHQSSY---GGQSGSTAPAIPYGAYNGPV--PGYQQTPPQGMSRA 62 PP P G +P P S Q G A A P G P PG + P Q + Sbjct: 361 PPAQPLGPAKP--PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418 Query: 63 PPSSGAPPA-STAQAPCG-QAAYGQFGQGDV---QNGPSSTVQMQRLPGSQPFG------ 111 P + P S A+AP + Q G G + Q GP T Q P P Sbjct: 419 KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAK 478 Query: 112 -SPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASAS 170 P P +PP QP P S Q + Q G P+P G P SA Sbjct: 479 PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538 Query: 171 GSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPR 222 S Q P+SQ +Q P S S+ PP+ G P+ Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPK 586 Score = 38.9 bits (89), Expect = 0.027 Identities = 65/256 (25%), Positives = 89/256 (34%), Gaps = 53/256 (20%) Query: 15 QPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTA 74 QP+ + P S S +T P IP + TPP A PS PP Sbjct: 756 QPKMVKPTTDLVS--SSSATTKPDIPSSKVQSQAEE-KTTPPLKTDSAKPSQSFPPTGEK 812 Query: 75 QAPCGQAAYGQFGQGDV---QNGPSST--------------------VQMQRLPGSQPF- 110 +P A + GPSS +M P ++P Sbjct: 813 VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872 Query: 111 -GSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQIS-GAVAPAPPS---------SGLG 159 GSP P G +P Q P S + Q ++ G++ AP S +G Sbjct: 873 KGSPTPP-GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931 Query: 160 FGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASG 219 FG S+ S + + ++ GQ P SQ+ PG Q APSQ PP S Sbjct: 932 FGFGASIFSQASNLISTA-------GQPGPHSQSG--PGAPMKQAPAPSQ-----PPTSQ 977 Query: 220 GPRLPSMTGPLLPGQS 235 GP + P P +S Sbjct: 978 GPPKSTGQAPPAPAKS 993 Score = 32.0 bits (71), Expect = 3.3 Identities = 40/179 (22%), Positives = 61/179 (34%), Gaps = 31/179 (17%) Query: 96 SSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPP- 154 SS++ + P P P P PP P PP + + ++ V A P Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPL 2455 Query: 155 --------------SSGLGF-----GPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQG 195 S+GL P + S P+ ++ P+ PP++ Sbjct: 2456 FDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPV 2515 Query: 196 HPGIQT---------PQRSAPSQASSFT--PPASGGPRLPSMTGPLLPGQSFGGPSVSQ 243 P + T P+ + S SS T S +LPS T PL P + P S+ Sbjct: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574 >gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo sapiens] Length = 245 Score = 67.8 bits (164), Expect = 5e-11 Identities = 67/238 (28%), Positives = 85/238 (35%), Gaps = 41/238 (17%) Query: 102 QRLPGSQPFGSPLAPVG-------NQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPP 154 Q PGS P+ +P AP + P P+GP PT + P+ P Sbjct: 32 QGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPAPTG---------------MYPSVP 76 Query: 155 SSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFT 214 +G GPP + S P G G YP P +P P P + T Sbjct: 77 PTGPPPGPPAPFPPSGPSCPPPG--GPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPT 134 Query: 215 PPASGGPRLP---SMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMH 271 PA+ GP P +GP PG P+ + P + S P PP Q G P+P Sbjct: 135 DPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMP-YPSPGPYPAPPPPQAPGAAPPVPWGT 193 Query: 272 SPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDAIPSP 329 P PG A GP + Y P + PT G P P P A P P Sbjct: 194 VP--PG-----------AWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMP 238 Score = 51.6 bits (122), Expect = 4e-06 Identities = 64/218 (29%), Positives = 75/218 (34%), Gaps = 52/218 (23%) Query: 6 SVPPV-PPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPP 64 SVPP PP G P P P G AP +P GP P TP P Sbjct: 74 SVPPTGPPPGPPAPFPPSGPSCPPPG-GPYPAPTVPGPGPTGPYP----TPNMPFPELPR 128 Query: 65 SSGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPG-SQPFGSPLAPVGNQPPV 123 GAP A P G G + +GP + + P + P+ SP P PP Sbjct: 129 PYGAPTDPAAAGPLGP-------WGSMSSGPWAPGMGGQYPTPNMPYPSP-GPYPAPPPP 180 Query: 124 LQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYP 183 P PP G V P +GPP + +GS+P GL YP Sbjct: 181 QAPGAAPPVPW------------GTVPPG------AWGPPAPYPAPTGSYPTPGL---YP 219 Query: 184 QGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGP 221 P Q P S PS A PP GGP Sbjct: 220 TPSNP----------FQVP--SGPSGA----PPMPGGP 241 Score = 46.2 bits (108), Expect = 2e-04 Identities = 47/174 (27%), Positives = 59/174 (33%), Gaps = 13/174 (7%) Query: 151 PAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQA 210 P P G P + SA S P SGL PP + P P PS Sbjct: 27 PGQPPQGWPGSNPWNNPSAPSSVP-SGL---------PPSATPSTVPFGPAPTGMYPSVP 76 Query: 211 SSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLG-PLPP 269 + PP P PS PG + P+V P P P ++ P G P P Sbjct: 77 PTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDP 136 Query: 270 MHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDP 323 + + +G + P G Q Y P P+ G P PP P P P Sbjct: 137 AAAGPLGPWGSMSSGPWAPGMGGQ--YPTPNMPYPSPGPYPAPPPPQAPGAAPP 188 Score = 41.6 bits (96), Expect = 0.004 Identities = 31/96 (32%), Positives = 36/96 (37%), Gaps = 30/96 (31%) Query: 225 SMTGPLLPGQSFGGPSV-SQPNHVSSPPQALPPG-TQMTGPLGPLPPMHSPQQPGYQPQQ 282 S T P P Q + G + + P+ SS P LPP T T P GP P Sbjct: 23 SNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPAPT------------- 69 Query: 283 NGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPP 318 G YP+ P G PGPP P PP Sbjct: 70 ---------------GMYPSVPPTGPPPGPPAPFPP 90 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 67.4 bits (163), Expect = 7e-11 Identities = 65/190 (34%), Positives = 68/190 (35%), Gaps = 26/190 (13%) Query: 144 QISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQ 203 Q+SG PP P G FP + G G A P P QTP Sbjct: 179 QMSGEGKAGPPGGSSRAAFPQG-GRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPP 237 Query: 204 RSAPSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQ-ALPPGTQM-T 261 R P G P P GP PGQ P PN PP L PG Sbjct: 238 R-----------PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQ 286 Query: 262 GPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPL-PPKR 320 PLGPLPP P PGY GP GP GP P F P PP PL PP Sbjct: 287 PPLGPLPPGPPPPVPGY--------GPPPGPPPPQQGPPPPPGPF--PPRPPGPLGPPLT 336 Query: 321 L-DPDAIPSP 329 L P +P P Sbjct: 337 LAPPPHLPGP 346 Score = 61.2 bits (147), Expect = 5e-09 Identities = 66/246 (26%), Positives = 82/246 (33%), Gaps = 24/246 (9%) Query: 60 SRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNG--PSSTVQMQRLPGSQPFGSPLAPV 117 SR SG P G ++ F QG G P + R PG G P P Sbjct: 171 SRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPF 230 Query: 118 -GNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNS 176 Q P P GPP G + +A PP+ G PP P Sbjct: 231 PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA-GPPNRGDRPPPPVLFPGQPFGQPP- 288 Query: 177 GLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLLPGQSF 236 G P G PP+ PG PQ+ P PP PR P GP L Sbjct: 289 --LGPLPPGPPPPVPGYGPPPGPPPPQQGPPP------PPGPFPPRPPGPLGPPL----- 335 Query: 237 GGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHS--PQQPGYQPQQNGSFG-PARGPQ 293 +++ P H+ PP PP P PP +S P P +G P + Sbjct: 336 ---TLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR 392 Query: 294 SNYGGP 299 +YG P Sbjct: 393 GDYGPP 398 Score = 53.1 bits (126), Expect = 1e-06 Identities = 63/217 (29%), Positives = 78/217 (35%), Gaps = 34/217 (15%) Query: 9 PVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGA 68 P P G P P +G T P P G GP PG PP G PP +G Sbjct: 220 PAGPGGPPPPF-----------PAGQTPPRPPLGP-PGP-PGPPGPPPPGQVLPPPLAGP 266 Query: 69 PPASTAQAP----CGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVL 124 P P GQ +GQ G + GP V PG P P P PP Sbjct: 267 PNRGDRPPPPVLFPGQ-PFGQPPLGPLPPGPPPPV-----PGYGPPPGPPPPQQGPPPPP 320 Query: 125 QPYGP-------PPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSG 177 P+ P PP + L G GA PAP + F PPT+ S + + G Sbjct: 321 GPFPPRPPGPLGPPLTLAPPPHLPGPP-PGAPPPAPHVNPAFFPPPTN--SGMPTSDSRG 377 Query: 178 LYGSYPQGQAPPLSQAQ-GHPGIQTPQRSAPSQASSF 213 + P G+ PP + G PG + P + F Sbjct: 378 PPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEF 414 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 66.6 bits (161), Expect = 1e-10 Identities = 108/442 (24%), Positives = 144/442 (32%), Gaps = 86/442 (19%) Query: 8 PPVPPFGQPQPIYPGYHQSSYGGQSGSTAPA-IPYGA--------------YNGPVPGYQ 52 PP PP P P P S +GS AP + Y + P P Sbjct: 633 PPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVM 692 Query: 53 QT---------PPQGMSRAPPSSGAPP------ASTAQAPCGQAAYGQFGQGDVQNGPSS 97 Q+ PP G+ PP PP A APC + Q P Sbjct: 693 QSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPS----LPQFSAPPPPLK 748 Query: 98 TVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSG 157 Q+Q + P P P P L P PP + S ++ V A P + Sbjct: 749 IHQVQHITQVAPPTPP--PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806 Query: 158 LGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPA 217 PP A +FP S + S P P + P + P Q S P Sbjct: 807 T---PPVPPAKKQPAFPASYIPPSPPT------------PPVPVPPPTLPKQQSFCAKPP 851 Query: 218 SGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQP- 276 PS P+ PSV + PP PP + + PL P+P +PQ P Sbjct: 852 ------PSPLSPV--------PSVVKQIASQFPPPPTPPAME-SQPLKPVPANVAPQSPP 896 Query: 277 --GYQPQQNGSFGPARGPQSNYGGPYP-AAPTFGSQPGPPQPLPPKRLDPDAIPSPIQVI 333 +P+ S P P ++ P P ++ F P P P PP P A P+P Sbjct: 897 AVKAKPKWQPSSIPV--PSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTP---- 950 Query: 334 EDDRNNRGTEPFVTGVRG--QVPPLVTTNFLVKDQGNAS-PRYIRCTSYNIPCTSDMAKQ 390 D + G + T G + PP N +K A P R P + + Sbjct: 951 -DKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKR------PSVDSLVSK 1003 Query: 391 AQVPLAAVIKPLARLPPEEASP 412 P + LPP A P Sbjct: 1004 FTPPAESGSPSKETLPPPAAPP 1025 Score = 58.9 bits (141), Expect = 3e-08 Identities = 100/407 (24%), Positives = 138/407 (33%), Gaps = 87/407 (21%) Query: 9 PVPPFGQPQPIYPGYHQSSYGGQSGSTAPAIPYGAY---NGPVPGYQQTPPQGMSRAPPS 65 P+PP P+P+ +S + + AP + A PVP ++ P S PPS Sbjct: 772 PLPPQAPPKPLVTIPAPTS----TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827 Query: 66 SGAPPASTAQAPCGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGN------ 119 PP P T+ Q+ ++P SPL+PV + Sbjct: 828 PPTPPVPV---------------------PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866 Query: 120 -------QPPVLQ------------PYGPPPTSAQVATQLSGMQI-----------SGAV 149 PP ++ P PP A+ Q S + + S V Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926 Query: 150 APAPPSSGLGFGPPTSLASASGSFPNSGLYG------SYPQGQAPP-----LSQAQGHPG 198 P PP S + PP +AS + SG G S P G+ PP S + G Sbjct: 927 FPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG 986 Query: 199 IQTPQRSAP---SQASSFTPPA-SGGP---RLPSMTGPLLPGQ-SFGG---PSVSQPNHV 247 + P+ P S S FTPPA SG P LP P PG+ + G P V Q V Sbjct: 987 AEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCV 1046 Query: 248 SSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFG 307 S+ L + + P PP S P P+ P P G P Sbjct: 1047 SAKAPVLSGRGKDSVVEFPSPPSDSDFPPP-PPETELPLPPIEIPAVFSGNTSPKVAVVN 1105 Query: 308 SQPGPPQPLPPKRLDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVP 354 QP + K+ P P + +P + V QVP Sbjct: 1106 PQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVP 1152 Score = 52.4 bits (124), Expect = 2e-06 Identities = 80/329 (24%), Positives = 123/329 (37%), Gaps = 52/329 (15%) Query: 26 SSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQ 85 SS +SGS++ +IP N + G+S P+ S + + + Sbjct: 530 SSSSIKSGSSSSSIPESQSN-----HSNQSDSGVSDTQPAGHVRSQSIVSS-----VFSE 579 Query: 86 FGQGDVQNGPSSTVQMQRLPGSQPFGSPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQI 145 + Q SS +M+ + ++P+ S + P+ QP ++ PY T++Q + L Sbjct: 580 AWKRGTQLEESSKARMESM--NRPYTSLVPPLSPQPKIVTPY----TASQPSPPLPPPPP 633 Query: 146 SGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRS 205 P PP PP L S S P++G A P+ + I Q + Sbjct: 634 PPPPPPPPPPP-----PPPPLPSQSA--PSAG--------SAAPMFVK--YSTITRLQNA 676 Query: 206 APSQASSFTPPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLG 265 + + F PP T P++ QS + PN V PP PP + Sbjct: 677 SQHSGALFKPP----------TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726 Query: 266 PLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPPKRLDPDA 325 L P +P P PQ + P + Q + A PT P PP P+P L P A Sbjct: 727 QLKP--APCAPSL-PQFSAPPPPLKIHQVQHITQV-APPT----PPPPPPIPAP-LPPQA 777 Query: 326 IPSPIQVIEDDRNNRGTEPFVTGVRGQVP 354 P P+ I + + P VT P Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.135 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 49,895,636 Number of Sequences: 37866 Number of extensions: 3042298 Number of successful extensions: 25365 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 133 Number of HSP's successfully gapped in prelim test: 1702 Number of HSP's that attempted gapping in prelim test: 14131 Number of HSP's gapped (non-prelim): 7608 length of query: 1094 length of database: 18,247,518 effective HSP length: 113 effective length of query: 981 effective length of database: 13,968,660 effective search space: 13703255460 effective search space used: 13703255460 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.