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Search of human proteins with 38327539
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38327539 inositol polyphosphate-5-phosphatase E [Homo
sapiens]
(644 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 1295 0.0
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 139 6e-33
gi|26190608 synaptojanin 2 [Homo sapiens] 139 6e-33
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 138 1e-32
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 138 1e-32
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 137 3e-32
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 135 9e-32
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 135 9e-32
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 135 9e-32
gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs... 127 3e-29
gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso... 115 2e-25
gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso... 115 2e-25
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas... 106 8e-23
gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho... 93 9e-19
gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H... 75 2e-13
gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho... 75 2e-13
gi|182507165 thymus expressed gene 3-like [Homo sapiens] 53 8e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 52 1e-06
gi|226498192 atonal homolog 8 [Homo sapiens] 52 2e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 2e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 52 2e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 52 2e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 52 2e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 52 2e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 51 3e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 51 4e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 50 5e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 50 6e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 50 6e-06
gi|239752280 PREDICTED: similar to family with sequence similari... 49 1e-05
>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
Length = 644
Score = 1295 bits (3350), Expect = 0.0
Identities = 644/644 (100%), Positives = 644/644 (100%)
Query: 1 MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSG 60
MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSG
Sbjct: 1 MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSG 60
Query: 61 EDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEG 120
EDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEG
Sbjct: 61 EDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEG 120
Query: 121 PGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAG 180
PGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAG
Sbjct: 121 PGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAG 180
Query: 181 SSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPR 240
SSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPR
Sbjct: 181 SSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPR 240
Query: 241 SPLACDDCSLRSAKSSFSLLAPIRSKDVRSRSYLEGSLLASGALLGADELARYFPDRNVA 300
SPLACDDCSLRSAKSSFSLLAPIRSKDVRSRSYLEGSLLASGALLGADELARYFPDRNVA
Sbjct: 241 SPLACDDCSLRSAKSSFSLLAPIRSKDVRSRSYLEGSLLASGALLGADELARYFPDRNVA 300
Query: 301 LFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHY 360
LFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHY
Sbjct: 301 LFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHY 360
Query: 361 VLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLF 420
VLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLF
Sbjct: 361 VLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLF 420
Query: 421 ITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNF 480
ITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNF
Sbjct: 421 ITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNF 480
Query: 481 RLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGK 540
RLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGK
Sbjct: 481 RLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGK 540
Query: 541 DTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRD 600
DTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRD
Sbjct: 541 DTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRD 600
Query: 601 NIPLAAGKFDRELYLLGIKRRISKEIQRQQALQSQNSSTICSVS 644
NIPLAAGKFDRELYLLGIKRRISKEIQRQQALQSQNSSTICSVS
Sbjct: 601 NIPLAAGKFDRELYLLGIKRRISKEIQRQQALQSQNSSTICSVS 644
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 139 bits (351), Expect = 6e-33
Identities = 110/378 (29%), Positives = 168/378 (44%), Gaps = 73/378 (19%)
Query: 276 GSLLASGALLGA--DELARYFPDRNVALFVATWNMQGQKELPP------SLDEFLLPA-- 325
GSL AS +L + + +Y + + + V TWN+ G K+ +L ++LL A
Sbjct: 503 GSLRASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPK 562
Query: 326 ---------EADYAQDLYVIGVQE------------GCSDRREWETRLQETLGPH--YVL 362
+ D++ IG +E ++++ W LQ+T+ YVL
Sbjct: 563 LAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVL 622
Query: 363 LSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFIT 422
L+S + + +FIR F +V TV T + KGA+ I F TS F+
Sbjct: 623 LASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVC 682
Query: 423 SHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRL 482
SHF +G +V ER D+ + L P + D VFW GDFN+R+
Sbjct: 683 SHFAAGQSQVKERNEDFIEIARKLSFPMG------------RMLFSHDYVFWCGDFNYRI 730
Query: 483 SGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDT 542
V L+ Q + +L+ DQLI + G +F+GF E + F P+YK+D+ D
Sbjct: 731 DLPNEEVKELIRQQ---NWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDD 787
Query: 543 YDSTSKQRTPSYTDRVLYRSR----------------HKGDICPVSYSSCPG-------- 578
YD++ K RTP++TDRVL+R R D + Y+ PG
Sbjct: 788 YDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRA 847
Query: 579 -IKTSDHRPVYGLFRVKV 595
+KTSDHRPV L + +
Sbjct: 848 ELKTSDHRPVVALIDIDI 865
Score = 39.7 bits (91), Expect = 0.009
Identities = 48/195 (24%), Positives = 76/195 (38%), Gaps = 26/195 (13%)
Query: 11 SEPAPQPPEGRTL-QGQLPGAP--PAQRAGSPPDAPGSESPALACSTPATPSGEDPPARA 67
S P P + T+ +G +P P P++ P P ++S + PATP + PA+
Sbjct: 1039 SSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQ-PATPLPQKDPAQ- 1096
Query: 68 APIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHS 127
P+ P+ P PR + R G R+ SP G GPG
Sbjct: 1097 -PLEPKRPPPPRPVAPPTRPAPPQRPPPPSG-------RSQPSPQAGLA---GPG----- 1140
Query: 128 CSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPS 187
P ST+ IP GV+S+ + + L+ + S + + + + +
Sbjct: 1141 --PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQA 1198
Query: 188 LLPPR---PPPALSL 199
PP+ PPPA L
Sbjct: 1199 AFPPQSSLPPPAQRL 1213
Score = 35.8 bits (81), Expect = 0.13
Identities = 50/197 (25%), Positives = 70/197 (35%), Gaps = 49/197 (24%)
Query: 9 RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
+P+ P PQ + L+ P PP R +PP P P PSG P+ A
Sbjct: 1084 QPATPLPQKDPAQPLE---PKRPPPPRPVAPPTRPAPP------QRPPPPSGRSQPSPQA 1134
Query: 69 PIAPRPP-----ARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTS-PSRGSVQSEGPG 122
+A P ARP + + R + E+++ TS S+GS P
Sbjct: 1135 GLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPL 1194
Query: 123 APAHSCSP----PCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAV 178
P + P P + LQE PL VA+ P
Sbjct: 1195 KPQAAFPPQSSLPPPAQRLQE--------------------PLVPVAAPMPQ-------- 1226
Query: 179 AGSSPRLPSLLPPRPPP 195
+G P L + PP+PPP
Sbjct: 1227 SGPQPNLET--PPQPPP 1241
>gi|26190608 synaptojanin 2 [Homo sapiens]
Length = 1496
Score = 139 bits (351), Expect = 6e-33
Identities = 114/386 (29%), Positives = 174/386 (45%), Gaps = 82/386 (21%)
Query: 276 GSLLASGALLGADELARYFPDRN--------VALFVATWNMQGQKELPPS------LDEF 321
G LL S ALL + + +R + + + TWN+ G K+ + L ++
Sbjct: 499 GMLLDSTALLVTPRILKAMTERQSEFTNFKRIRIAMGTWNVNGGKQFRSNVLRTAELTDW 558
Query: 322 LLPA----------EADYAQDLYVIGVQE------------GCSDRREWETRLQETLGP- 358
LL + + D++ +G +E ++++ W +LQ+ +
Sbjct: 559 LLDSPQLSGATDSQDDSSPADIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQKAISRS 618
Query: 359 -HYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTS 417
Y+LL+SA + + +F+R + F +V TV T + + KGA+GI F F TS
Sbjct: 619 HRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTS 678
Query: 418 FLFITSHFTSGDGKVAERLLDYTRTVQALVLP--RNVPDTNPYRSSAADVTTRFDEVFWF 475
F FI SH T+G +V ER DY Q L P RNV D VFW
Sbjct: 679 FCFICSHLTAGQSQVKERNEDYKEITQKLCFPMGRNV--------------FSHDYVFWC 724
Query: 476 GDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYK 535
GDFN+R+ + + D LL+ DQL + G IFK F E I+F P+YK
Sbjct: 725 GDFNYRID---LTYEEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFHEGAINFGPTYK 781
Query: 536 FDIGKDTYDSTSKQRTPSYTDRVL-YRSRHKGD---------------ICPVSYSSCPG- 578
+D+G YD++ K RTP++TDRVL +R +H D V ++ PG
Sbjct: 782 YDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWSPGA 841
Query: 579 --------IKTSDHRPVYGLFRVKVR 596
++ SDHRPV + V+V+
Sbjct: 842 LQYYGRAELQASDHRPVLAIVEVEVQ 867
Score = 34.7 bits (78), Expect = 0.28
Identities = 50/196 (25%), Positives = 73/196 (37%), Gaps = 25/196 (12%)
Query: 47 SPALACSTPATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGW-----RRRRFRGS-Q 100
SP+ + S P P PP R P + + ++S G R G+ Q
Sbjct: 1091 SPSRSLSVPNRPRPPQPPQRPPPPTGLMVKKSASDASISSGTHGQYSILQTARLLPGAPQ 1150
Query: 101 EDLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNP 160
+ +AR G S Q + A + CL ++RG S E S + P
Sbjct: 1151 QPPKARTGISKPYNVKQIKTTNAQEAEAAIRCLL-------EARGGASEEALSAVA---P 1200
Query: 161 LSGVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYK 220
ASS P A +P+ P LLP RPPP + I +LR K S ++
Sbjct: 1201 RDLEASSEPE--PTPGAAKPETPQAPPLLPRRPPPRVPA-IKKPTLRRTGKPLSPEEQFE 1257
Query: 221 LRAQPLLVRAHSSLGP 236
+ H ++GP
Sbjct: 1258 QQT------VHFTIGP 1267
Score = 31.2 bits (69), Expect = 3.1
Identities = 50/223 (22%), Positives = 78/223 (34%), Gaps = 32/223 (14%)
Query: 15 PQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAPIAPRP 74
P P+ RT Q P+ R + +AP P S P PP A P+ P+
Sbjct: 1284 PPVPKPRTFQPGKAAERPSHRKPASDEAP----PGAGASVP-------PPLEAPPLVPKV 1332
Query: 75 PARPR--LERALSLDDKGWRRRRFRG-SQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPP 131
P R + A L + +G + ++ +G P+ G+V +G S + P
Sbjct: 1333 PPRRKKSAPAAFHLQVLQSNSQLLQGLTYNSSDSPSGHPPAAGTVFPQGDFLSTSSATSP 1392
Query: 132 CLSTSLQEIPKSRGVLSSERGS---------------PSSGGNPLSGVASSSPNLPHRDA 176
+ P++ +L + S +PL + SP D
Sbjct: 1393 DSDGTKAMKPEAAPLLGDYQDPFWNLLHHPKLLNNTWLSKSSDPLDS-GTRSPKRDPIDP 1451
Query: 177 AVAGSSPRLPSLLPPRPPPALS--LDIASDSLRTANKVDSDLA 217
AG+S L P L + I+ RTA +V LA
Sbjct: 1452 VSAGASAAKAELPPDHEHKTLGHWVTISDQEKRTALQVFDPLA 1494
>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
sapiens]
Length = 1188
Score = 138 bits (348), Expect = 1e-32
Identities = 102/320 (31%), Positives = 151/320 (47%), Gaps = 34/320 (10%)
Query: 299 VALFVATWNMQGQKELPPSLDEFLLPA--------EADYA-QDLYVIGVQEGCSDRREWE 349
+ +F+ TWNM G P + + L ADY D+YVIG QE +EW
Sbjct: 403 ITIFIGTWNM-GNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWL 461
Query: 350 TRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVE-------CSTVTTRIVSQIK 402
L+ +L + S V +L+ R ++ E E V T I + +
Sbjct: 462 EILKHSLQE---ITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLG 518
Query: 403 TKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSA 462
KGA+G+SF F GTS F+ SH TSG K R +Y ++ L L + S
Sbjct: 519 NKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLAL-------GDKKLSP 571
Query: 463 ADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKG 522
++T RF +FWFGD N+R+ + ++ + LL HDQL+ E R+ +F
Sbjct: 572 FNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLH 631
Query: 523 FQEPDIHFLPSYKFD-IGKDTYDSTSKQRT------PSYTDRVLYRSRHKGDICPVSYSS 575
F+E +I F P+Y+F+ + +D Y T ++ T PS+ DRVL++S + SY S
Sbjct: 632 FEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGS 691
Query: 576 CPGIKTSDHRPVYGLFRVKV 595
I TSDH PV+ F V
Sbjct: 692 TSDIMTSDHSPVFATFEAGV 711
>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
sapiens]
Length = 1189
Score = 138 bits (348), Expect = 1e-32
Identities = 102/320 (31%), Positives = 151/320 (47%), Gaps = 34/320 (10%)
Query: 299 VALFVATWNMQGQKELPPSLDEFLLPA--------EADYA-QDLYVIGVQEGCSDRREWE 349
+ +F+ TWNM G P + + L ADY D+YVIG QE +EW
Sbjct: 404 ITIFIGTWNM-GNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWL 462
Query: 350 TRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVE-------CSTVTTRIVSQIK 402
L+ +L + S V +L+ R ++ E E V T I + +
Sbjct: 463 EILKHSLQE---ITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLG 519
Query: 403 TKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSA 462
KGA+G+SF F GTS F+ SH TSG K R +Y ++ L L + S
Sbjct: 520 NKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLAL-------GDKKLSP 572
Query: 463 ADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKG 522
++T RF +FWFGD N+R+ + ++ + LL HDQL+ E R+ +F
Sbjct: 573 FNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLH 632
Query: 523 FQEPDIHFLPSYKFD-IGKDTYDSTSKQRT------PSYTDRVLYRSRHKGDICPVSYSS 575
F+E +I F P+Y+F+ + +D Y T ++ T PS+ DRVL++S + SY S
Sbjct: 633 FEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGS 692
Query: 576 CPGIKTSDHRPVYGLFRVKV 595
I TSDH PV+ F V
Sbjct: 693 TSDIMTSDHSPVFATFEAGV 712
>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
sapiens]
Length = 1258
Score = 137 bits (345), Expect = 3e-32
Identities = 102/320 (31%), Positives = 155/320 (48%), Gaps = 37/320 (11%)
Query: 299 VALFVATWNMQG------------QKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRR 346
+++F+ TWNM K L +LDE + D+YV G QE R
Sbjct: 424 ISVFIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIP----HDIYVFGTQENSVGDR 479
Query: 347 EW----ETRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIK 402
EW L+E Y ++ + + +++ ++ + S V S+V T I + +
Sbjct: 480 EWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLG 539
Query: 403 TKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSA 462
KGA+G+SF F GTSF F+ H TSG+ K A R +Y ++ L L + +A
Sbjct: 540 NKGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSL-------GDRQLNA 592
Query: 463 ADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKG 522
D++ RF +FWFGD N+RL + +L + LL+ DQL E K +F
Sbjct: 593 FDISLRFTHLFWFGDLNYRLD---MDIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLR 649
Query: 523 FQEPDIHFLPSYKFDIG-KDTYDSTSKQRT------PSYTDRVLYRSRHKGDICPVSYSS 575
F E +I F P+Y+++ G +DTY ++ T PS+ DR+L++S + I SY
Sbjct: 650 FSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGC 709
Query: 576 CPGIKTSDHRPVYGLFRVKV 595
I TSDH PV+G F V V
Sbjct: 710 TDDIVTSDHSPVFGTFEVGV 729
Score = 30.8 bits (68), Expect = 4.0
Identities = 18/56 (32%), Positives = 23/56 (41%), Gaps = 3/56 (5%)
Query: 12 EPAPQPPEGRTL---QGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPP 64
E P PP+ R + + P PP + S G SP A TP P+ E P
Sbjct: 120 EREPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAESAP 175
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 135 bits (341), Expect = 9e-32
Identities = 104/360 (28%), Positives = 159/360 (44%), Gaps = 71/360 (19%)
Query: 292 RYFPDRNVALFVATWNMQGQKELPP------SLDEFLLPA-----------EADYAQDLY 334
+Y + + + V TWN+ G K+ +L ++LL A + D++
Sbjct: 526 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 585
Query: 335 VIGVQE------------GCSDRREWETRLQETLGPH--YVLLSSAAHGVLYMSLFIRRD 380
IG +E ++++ W LQ+T+ YVLL+S + + +FIR
Sbjct: 586 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 645
Query: 381 LIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYT 440
F +V TV T + KGA+ I F TS F+ SHF +G +V ER D+
Sbjct: 646 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 705
Query: 441 RTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVD 500
+ L P + D VFW GDFN+R+ V L+ Q +
Sbjct: 706 EIARKLSFPMG------------RMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQ---N 750
Query: 501 VPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLY 560
+L+ DQLI + G +F+GF E + F P+YK+D+ D YD++ K RTP++TDRVL+
Sbjct: 751 WDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLW 810
Query: 561 RSR----------------HKGDICPVSYSSCPG---------IKTSDHRPVYGLFRVKV 595
R R D + Y+ PG +KTSDHRPV L + +
Sbjct: 811 RRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDI 870
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/212 (24%), Positives = 84/212 (39%), Gaps = 34/212 (16%)
Query: 11 SEPAPQPPEGRTL-QGQLPGAP--PAQRAGSPPDAPGSESPALACSTPATPSGEDPPAR- 66
S P P + T+ +G +P P P++ P P ++S + PATP + PA+
Sbjct: 1044 SSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQ-PATPLPQKDPAQP 1102
Query: 67 ------------AAPIAPRPPAR---PRLERALSLDDKGWRRRRFRG-SQEDLEARNGTS 110
A P P PP R P R+ + K + + G +++D R+ S
Sbjct: 1103 LEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPS 1162
Query: 111 PSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPN 170
P G GPG P ST+ IP GV+S+ + + L+ + S +
Sbjct: 1163 PQAGLA---GPG-------PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTS 1212
Query: 171 LPHRDAAVAGSSPRLPSLLPPR---PPPALSL 199
+ + + + PP+ PPPA L
Sbjct: 1213 ETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL 1244
Score = 33.5 bits (75), Expect = 0.62
Identities = 52/201 (25%), Positives = 69/201 (34%), Gaps = 43/201 (21%)
Query: 6 ENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSP-------PDAPG-SESPALACSTPAT 57
E RP P P P R Q P P R+ +P P +PG + + S P+
Sbjct: 1104 EPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSP 1163
Query: 58 PSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQ 117
+G P A RP PR +S R R + E S S+ S
Sbjct: 1164 QAGLAGPGPAGYSTARPTIPPR-AGVISAPQSHARASAGRLTPE--------SQSKTSET 1214
Query: 118 SEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSG---GNPLSGVASSSPNLPHR 174
S+G ST L E K + + P PL VA+ P
Sbjct: 1215 SKG-------------STFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQ---- 1257
Query: 175 DAAVAGSSPRLPSLLPPRPPP 195
+G P L + PP+PPP
Sbjct: 1258 ----SGPQPNLET--PPQPPP 1272
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 135 bits (341), Expect = 9e-32
Identities = 104/360 (28%), Positives = 159/360 (44%), Gaps = 71/360 (19%)
Query: 292 RYFPDRNVALFVATWNMQGQKELPP------SLDEFLLPA-----------EADYAQDLY 334
+Y + + + V TWN+ G K+ +L ++LL A + D++
Sbjct: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
Query: 335 VIGVQE------------GCSDRREWETRLQETLGPH--YVLLSSAAHGVLYMSLFIRRD 380
IG +E ++++ W LQ+T+ YVLL+S + + +FIR
Sbjct: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
Query: 381 LIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYT 440
F +V TV T + KGA+ I F TS F+ SHF +G +V ER D+
Sbjct: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
Query: 441 RTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVD 500
+ L P + D VFW GDFN+R+ V L+ Q +
Sbjct: 745 EIARKLSFPMG------------RMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQ---N 789
Query: 501 VPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLY 560
+L+ DQLI + G +F+GF E + F P+YK+D+ D YD++ K RTP++TDRVL+
Sbjct: 790 WDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLW 849
Query: 561 RSR----------------HKGDICPVSYSSCPG---------IKTSDHRPVYGLFRVKV 595
R R D + Y+ PG +KTSDHRPV L + +
Sbjct: 850 RRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDI 909
Score = 39.3 bits (90), Expect = 0.011
Identities = 48/200 (24%), Positives = 71/200 (35%), Gaps = 37/200 (18%)
Query: 9 RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
+P+ P PQ + L+ P PP R +PP P P PSG PA
Sbjct: 1128 QPATPLPQKDPAQPLE---PKRPPPPRPVAPPTRPAPP------QRPPPPSGARSPA--- 1175
Query: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRG------SQEDLEARNGTSPSRGSVQSEGPG 122
P R + G RR +++D R+ SP G GPG
Sbjct: 1176 ------PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLA---GPG 1226
Query: 123 APAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSS 182
P ST+ IP GV+S+ + + L+ + S + + +
Sbjct: 1227 -------PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEP 1279
Query: 183 PRLPSLLPPR---PPPALSL 199
+ + PP+ PPPA L
Sbjct: 1280 LKPQAAFPPQSSLPPPAQRL 1299
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 135 bits (341), Expect = 9e-32
Identities = 104/360 (28%), Positives = 159/360 (44%), Gaps = 71/360 (19%)
Query: 292 RYFPDRNVALFVATWNMQGQKELPP------SLDEFLLPA-----------EADYAQDLY 334
+Y + + + V TWN+ G K+ +L ++LL A + D++
Sbjct: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
Query: 335 VIGVQE------------GCSDRREWETRLQETLGPH--YVLLSSAAHGVLYMSLFIRRD 380
IG +E ++++ W LQ+T+ YVLL+S + + +FIR
Sbjct: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
Query: 381 LIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYT 440
F +V TV T + KGA+ I F TS F+ SHF +G +V ER D+
Sbjct: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
Query: 441 RTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVD 500
+ L P + D VFW GDFN+R+ V L+ Q +
Sbjct: 745 EIARKLSFPMG------------RMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQ---N 789
Query: 501 VPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLY 560
+L+ DQLI + G +F+GF E + F P+YK+D+ D YD++ K RTP++TDRVL+
Sbjct: 790 WDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLW 849
Query: 561 RSR----------------HKGDICPVSYSSCPG---------IKTSDHRPVYGLFRVKV 595
R R D + Y+ PG +KTSDHRPV L + +
Sbjct: 850 RRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDI 909
Score = 39.3 bits (90), Expect = 0.011
Identities = 48/200 (24%), Positives = 71/200 (35%), Gaps = 37/200 (18%)
Query: 9 RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
+P+ P PQ + L+ P PP R +PP P P PSG PA
Sbjct: 1128 QPATPLPQKDPAQPLE---PKRPPPPRPVAPPTRPAPP------QRPPPPSGARSPA--- 1175
Query: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRG------SQEDLEARNGTSPSRGSVQSEGPG 122
P R + G RR +++D R+ SP G GPG
Sbjct: 1176 ------PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLA---GPG 1226
Query: 123 APAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSS 182
P ST+ IP GV+S+ + + L+ + S + + +
Sbjct: 1227 -------PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEP 1279
Query: 183 PRLPSLLPPR---PPPALSL 199
+ + PP+ PPPA L
Sbjct: 1280 LKPQAAFPPQSSLPPPAQRL 1299
>gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor
[Homo sapiens]
Length = 913
Score = 127 bits (319), Expect = 3e-29
Identities = 91/321 (28%), Positives = 148/321 (46%), Gaps = 31/321 (9%)
Query: 297 RNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQE-----------GCSDR 345
+N F T+N+ GQ P L + A D+Y +G QE
Sbjct: 263 QNFRFFAGTYNVNGQS---PKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKE 319
Query: 346 REWETRLQETLGPH--YVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKT 403
EW + E L P Y + + + L+++++ + SEVE TV T I+ ++
Sbjct: 320 EEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGN 379
Query: 404 KGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAA 463
KG + I F F TS + SH + + R DY + + P P S
Sbjct: 380 KGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNH 439
Query: 464 DVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVV--DVPALLQHDQLIREMRKGSIFK 521
DV + W GD N+R+ +D + L+ D L +DQL ++ ++F+
Sbjct: 440 DV------ILWLGDLNYRIEE----LDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFE 489
Query: 522 GFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKT 581
GF E ++ F P+YK+D G D +D++ K R P++ DR+L++ + +I +SY S +KT
Sbjct: 490 GFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGK---NITQLSYQSHMALKT 546
Query: 582 SDHRPVYGLFRVKVRPGRDNI 602
SDH+PV +F + VR D +
Sbjct: 547 SDHKPVSSVFDIGVRVVNDEL 567
>gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase
isoform b [Homo sapiens]
Length = 893
Score = 115 bits (287), Expect = 2e-25
Identities = 90/313 (28%), Positives = 145/313 (46%), Gaps = 37/313 (11%)
Query: 302 FVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQE-----------GCSDRREWET 350
FV TWN+ GQ P S E L + + D+Y IG QE +EW
Sbjct: 243 FVGTWNVNGQS--PDSGLEPWLNCDPN-PPDIYCIGFQELDLSTEAFFYFESVKEQEWSM 299
Query: 351 RLQETLGPH--YVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALG 408
++ L Y + + + +F R+D + ++ TV T I+ ++ KG +
Sbjct: 300 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA 359
Query: 409 ISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTV--QALVLP-RNVPDTNPYRSSAADV 465
+ F F T+F + SH + R DY + V+P + +P N
Sbjct: 360 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN--------- 410
Query: 466 TTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLV--VDVPALLQHDQLIREMRKGSIFKGF 523
+ + V W GD N+RL + DA + L+ D+ LL+ DQL + + F F
Sbjct: 411 IMKHEVVIWLGDLNYRLC----MPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDF 466
Query: 524 QEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSD 583
E +I F+P+YK+D D +DS+ K R P++ DR+L+R ++ ++Y S +KTSD
Sbjct: 467 NEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGT---NVNQLNYRSHMELKTSD 523
Query: 584 HRPVYGLFRVKVR 596
H+PV LF + V+
Sbjct: 524 HKPVSALFHIGVK 536
>gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
isoform a [Homo sapiens]
Length = 901
Score = 115 bits (287), Expect = 2e-25
Identities = 90/313 (28%), Positives = 145/313 (46%), Gaps = 37/313 (11%)
Query: 302 FVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQE-----------GCSDRREWET 350
FV TWN+ GQ P S E L + + D+Y IG QE +EW
Sbjct: 243 FVGTWNVNGQS--PDSGLEPWLNCDPN-PPDIYCIGFQELDLSTEAFFYFESVKEQEWSM 299
Query: 351 RLQETLGPH--YVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALG 408
++ L Y + + + +F R+D + ++ TV T I+ ++ KG +
Sbjct: 300 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA 359
Query: 409 ISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTV--QALVLP-RNVPDTNPYRSSAADV 465
+ F F T+F + SH + R DY + V+P + +P N
Sbjct: 360 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN--------- 410
Query: 466 TTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLV--VDVPALLQHDQLIREMRKGSIFKGF 523
+ + V W GD N+RL + DA + L+ D+ LL+ DQL + + F F
Sbjct: 411 IMKHEVVIWLGDLNYRLC----MPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDF 466
Query: 524 QEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSD 583
E +I F+P+YK+D D +DS+ K R P++ DR+L+R ++ ++Y S +KTSD
Sbjct: 467 NEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGT---NVNQLNYRSHMELKTSD 523
Query: 584 HRPVYGLFRVKVR 596
H+PV LF + V+
Sbjct: 524 HKPVSALFHIGVK 536
>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase,
A [Homo sapiens]
Length = 638
Score = 106 bits (264), Expect = 8e-23
Identities = 92/333 (27%), Positives = 148/333 (44%), Gaps = 50/333 (15%)
Query: 303 VATWNMQGQKELPPSLDEFLLPAEADYAQ--DLYVIGVQEGCS--DRR--------EWET 350
V TWN+ G P + L D + D+ IG+QE S ++R +W
Sbjct: 59 VVTWNV-GTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLKDALFTDQWSE 117
Query: 351 RLQETLGP-HYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGI 409
+ LGP ++VL+SS + + LF + + F +V+ T + KG + +
Sbjct: 118 LFMDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVSV 177
Query: 410 SFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRF 469
FG F+ H + K AE+ D +T+ +L ++ A
Sbjct: 178 RLAAFGHMLCFLNCHLPAHMDK-AEQRKDNFQTILSL---------QQFQGPGAQGILDH 227
Query: 470 DEVFWFGDFNFRLSGG-----RTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQ 524
D VFWFGD NFR+ + +D+ + L + DQL I KGFQ
Sbjct: 228 DLVFWFGDLNFRIESYDLHFVKFAIDS-------DQLHQLWEKDQLNMAKNTWPILKGFQ 280
Query: 525 EPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLY-------------RSRHKGDICPV 571
E ++F P++KFD+G + YD+++K+R P++TDR+L+ R H+ +
Sbjct: 281 EGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQH 340
Query: 572 SYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPL 604
SY S SDH+PV F ++ RD++PL
Sbjct: 341 SYRSHMEYTVSDHKPVAAQFLLQF-AFRDDMPL 372
Score = 30.4 bits (67), Expect = 5.3
Identities = 36/118 (30%), Positives = 46/118 (38%), Gaps = 11/118 (9%)
Query: 42 APGSESPALACSTPATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQE 101
AP S SP+ S S AR +A RP +R R R S RR R + +
Sbjct: 502 APKSRSPSPGKSKRHR-SRSPGLARFPGLALRPSSRER--RGASRSPSPQSRRLSRVAPD 558
Query: 102 DLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGN 159
R+ SRGS + G P PP + SL +P L E P GG+
Sbjct: 559 ----RSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLP----ALRLETVDPGGGGS 608
>gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo
sapiens]
Length = 448
Score = 92.8 bits (229), Expect = 9e-19
Identities = 81/331 (24%), Positives = 141/331 (42%), Gaps = 48/331 (14%)
Query: 297 RNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQE----------GCSDRR 346
R +++ V TWN+ P L + L + D+YVIG+QE +
Sbjct: 12 RRLSIHVVTWNVASAAP-PLDLSDLLQLNNRNLNLDIYVIGLQELNSGIISLLSDAAFND 70
Query: 347 EWETRLQETLGP-HYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKG 405
W + L + L P ++ +S + + +F + + + + + T + KG
Sbjct: 71 SWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKG 130
Query: 406 ALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLP-RNVPDTNPYRSSAAD 464
+ I +G I H +RL + R ++ R++P+ +
Sbjct: 131 GVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDH------ 184
Query: 465 VTTRFDEVFWFGDFNFRLS--GGRTVVDALL--CQGLVVDVPALLQHDQLIREMRKGSIF 520
D + WFGD NFR+ G V +++ C G L + DQL + +
Sbjct: 185 -----DLIIWFGDMNFRIEDFGLHFVRESIKNRCYG------GLWEKDQLSIAKKHDPLL 233
Query: 521 KGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHK---GDICPV------ 571
+ FQE + F P+YKFD + YD++ K+R P++TDR+L+R + + G P+
Sbjct: 234 REFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHF 293
Query: 572 -----SYSSCPGIKTSDHRPVYGLFRVKVRP 597
YSS SDH+PV G F ++++P
Sbjct: 294 SLSLRGYSSHMTYGISDHKPVSGTFDLELKP 324
>gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 74.7 bits (182), Expect = 2e-13
Identities = 59/213 (27%), Positives = 96/213 (45%), Gaps = 36/213 (16%)
Query: 404 KGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLP-RNVPDTNPYRSSA 462
KG + I +G I H +RL + R ++ R++P+ +
Sbjct: 53 KGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDH---- 108
Query: 463 ADVTTRFDEVFWFGDFNFRLS--GGRTVVDALL--CQGLVVDVPALLQHDQLIREMRKGS 518
D + WFGD NFR+ G V +++ C G L + DQL +
Sbjct: 109 -------DLIIWFGDMNFRIEDFGLHFVRESIKNRCYG------GLWEKDQLSIAKKHDP 155
Query: 519 IFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHK---GDICPV---- 571
+ + FQE + F P+YKFD + YD++ K+R P++TDR+L+R + + G P+
Sbjct: 156 LLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPAS 215
Query: 572 -------SYSSCPGIKTSDHRPVYGLFRVKVRP 597
YSS SDH+PV G F ++++P
Sbjct: 216 HFSLSLRGYSSHMTYGISDHKPVSGTFDLELKP 248
>gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 74.7 bits (182), Expect = 2e-13
Identities = 59/213 (27%), Positives = 96/213 (45%), Gaps = 36/213 (16%)
Query: 404 KGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLP-RNVPDTNPYRSSA 462
KG + I +G I H +RL + R ++ R++P+ +
Sbjct: 53 KGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDH---- 108
Query: 463 ADVTTRFDEVFWFGDFNFRLS--GGRTVVDALL--CQGLVVDVPALLQHDQLIREMRKGS 518
D + WFGD NFR+ G V +++ C G L + DQL +
Sbjct: 109 -------DLIIWFGDMNFRIEDFGLHFVRESIKNRCYG------GLWEKDQLSIAKKHDP 155
Query: 519 IFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHK---GDICPV---- 571
+ + FQE + F P+YKFD + YD++ K+R P++TDR+L+R + + G P+
Sbjct: 156 LLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPAS 215
Query: 572 -------SYSSCPGIKTSDHRPVYGLFRVKVRP 597
YSS SDH+PV G F ++++P
Sbjct: 216 HFSLSLRGYSSHMTYGISDHKPVSGTFDLELKP 248
>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
Length = 629
Score = 53.1 bits (126), Expect = 8e-07
Identities = 66/241 (27%), Positives = 91/241 (37%), Gaps = 25/241 (10%)
Query: 9 RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
RP + +P P R + P +R G P +P + S A A S + + E AA
Sbjct: 288 RPPDASPSPGSARPAR-----EPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAA 342
Query: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSP-SRGSVQSEGPGAPAHS 127
P P PA RL +A + R G AR P +RG + P P
Sbjct: 343 PSPPDSPAEGRLVKAQYIPGAQAATRGLPGR----AARRKPPPLTRGRSVEQSP--PRER 396
Query: 128 CSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPS 187
+ E RG + + S S L G AS+ P+ P + PR
Sbjct: 397 PRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPR--- 453
Query: 188 LLPPR----PPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPRSPL 243
PPR P P L+ A R + + D AD + R +P RA ++ PG SP
Sbjct: 454 --PPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGR-RVRP---RAPAARVPGPGPSPS 507
Query: 244 A 244
A
Sbjct: 508 A 508
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/214 (25%), Positives = 70/214 (32%), Gaps = 26/214 (12%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQG----QLPGAPPAQRAGSPPDAPGSESPALACSTPAT 57
P + N P P P+G QG + +PP + G PP G P P
Sbjct: 143 PPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ--GGNQPQGPPPPPGK 200
Query: 58 PSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPS----- 112
P G P P P PP +P+ D+K R G + + G P
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQG-DNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259
Query: 113 ---------RGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSG 163
+G + +GP P PP S SR +G P GGN G
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR--SSRSPPGKPQGPPPQGGNQPQG 317
Query: 164 VASSSPNLPHRDAAVAGSSPR--LPSLLPPRPPP 195
P P G+ P+ P P PPP
Sbjct: 318 -PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 350
Score = 51.2 bits (121), Expect = 3e-06
Identities = 52/208 (25%), Positives = 70/208 (33%), Gaps = 24/208 (11%)
Query: 4 KAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDP 63
++ +L P PP+G + Q P +PP + G PP G P P P G P
Sbjct: 27 ESPSLIAGNPQGAPPQGGN-KPQGPPSPPGKPQGPPPQ--GGNQPQGPPPPPGKPQGPPP 83
Query: 64 PARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPS----------- 112
P P PP +P + DK R G + + G P
Sbjct: 84 QGGNKPQGPPPPGKP--QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 141
Query: 113 ---RGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSP 169
+G + +GP P PP + SR +G P GGN G P
Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSR--SSRSPPGKPQGPPPQGGNQPQG-PPPPP 198
Query: 170 NLPHRDAAVAGSSPR--LPSLLPPRPPP 195
P G+ P+ P P PPP
Sbjct: 199 GKPQGPPPQGGNKPQGPPPPGKPQGPPP 226
Score = 43.1 bits (100), Expect = 8e-04
Identities = 43/188 (22%), Positives = 56/188 (29%), Gaps = 37/188 (19%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAP 69
P +P PP+G G P PP P G + S P P G P P
Sbjct: 136 PGKPQGPPPQG----GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP 191
Query: 70 IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCS 129
P PP + P +G + +GP P
Sbjct: 192 QGPPPP----------------------------PGKPQGPPPQGGNKPQGPPPPGKPQG 223
Query: 130 PPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPR--LPS 187
PP + + +R +G P GGN G P P G+ P+ P
Sbjct: 224 PPPQGDNKSQ--SARSPPGKPQGPPPQGGNQPQG-PPPPPGKPQGPPPQGGNKPQGPPPP 280
Query: 188 LLPPRPPP 195
P PPP
Sbjct: 281 GKPQGPPP 288
Score = 36.6 bits (83), Expect = 0.074
Identities = 25/68 (36%), Positives = 30/68 (44%), Gaps = 6/68 (8%)
Query: 10 PSEPAPQPPEGRTLQGQLP-GAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
P +P PP+G G P G PP + PP GS+S + A S P P G
Sbjct: 322 PGKPQGPPPQG----GNKPQGPPPPGKPQGPPPQGGSKSRS-ARSPPGKPQGPPQQEGNN 376
Query: 69 PIAPRPPA 76
P P PPA
Sbjct: 377 PQGPPPPA 384
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 11/78 (14%)
Query: 10 PSEPAPQPPEGRTLQGQL---PGAP--PAQRAGSPPDAPGSESPALACSTPATPSGEDPP 64
P +P PP+G + PG P P Q+ G+ P P P A P P + PP
Sbjct: 342 PGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP----PPPAGGNPQQP--QAPP 395
Query: 65 ARAAPIAPRPPARPRLER 82
A PRPP R R
Sbjct: 396 AGQPQGPPRPPQGGRPSR 413
>gi|226498192 atonal homolog 8 [Homo sapiens]
Length = 321
Score = 52.0 bits (123), Expect = 2e-06
Identities = 30/73 (41%), Positives = 33/73 (45%), Gaps = 8/73 (10%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAP 69
P P P PP Q Q PG P AQ P PG L C+ PA P+ PPA AP
Sbjct: 119 PGLPTPPPPPPPAPQSQAPGGPEAQ----PFREPGLRPRILLCAPPARPAPSAPPAPPAP 174
Query: 70 ----IAPRPPARP 78
+ P PP RP
Sbjct: 175 PESTVRPAPPTRP 187
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 51.6 bits (122), Expect = 2e-06
Identities = 59/211 (27%), Positives = 79/211 (37%), Gaps = 48/211 (22%)
Query: 2 PSKAENLRP-SEPAPQPPEG---RTLQGQL--PGAPPAQRAGSPPDAPGSESPALACSTP 55
P + L P + P+PQ P LQ P +PP Q SPP +P S
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-------PVSPS 463
Query: 56 ATPSGEDPPARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPS 112
ATP + PP+ AAP + P PPA P + + + T P
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPM------------------------SPSATPPP 499
Query: 113 RGSVQSEGPG---APAHSCSPPCLST-SLQEIPKSRGVLSSERGSPSSGGNPLSGVASSS 168
+ P A +PP L+T LQ +P + S P+S +A+
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559
Query: 169 PNLPHRDAA----VAGSSPRLPSLLPPRPPP 195
P P AA V S P P+L PR PP
Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 590
Score = 50.8 bits (120), Expect = 4e-06
Identities = 61/216 (28%), Positives = 92/216 (42%), Gaps = 19/216 (8%)
Query: 1 MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDA------PGSESPALACST 54
+P A + RP P P + + + P+ A P A P S S + + +
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 55 PATPSGEDPPARAAPIAPRPPARPRLE--RALSLDDKGWRRRRFRGSQEDLEARNGTSPS 112
++P+ P AR P AP P++P+ + +AL R+ + L + +PS
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 113 -RGSVQSEGP---GAPAHSCSPPC-LSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASS 167
++QS+ P A HS S C L+T L P S S + PS P S +S
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 168 --SPNLPHRDAAVAGSSPRLPSLL--PPRPPPALSL 199
SP L + + SP L L PP+ PPAL+L
Sbjct: 369 LGSPTLQATHSFL--PSPPLSPLATPPPQAPPALAL 402
Score = 49.3 bits (116), Expect = 1e-05
Identities = 62/204 (30%), Positives = 78/204 (38%), Gaps = 25/204 (12%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPP-----DAPGSESPALACSTPA 56
P A L+ ++P PQ P PP Q SPP AP S S +L S A
Sbjct: 504 PLAAPPLQLAKPPPQAPPALA-------TPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
Query: 57 TPSGEDPPARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNG--TSP 111
TP + PP AAP + P PPA P L+ G G + L G P
Sbjct: 557 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-PDTSVSGPRLTLALAPGPPPPP 615
Query: 112 SRG-SVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPN 170
SR S GP HS S +TS E + RG S G ++ P + +A+ P
Sbjct: 616 SRSPSSTLSGPDLAGHSSS----ATSTPE--ELRGYDSGPEGGAAASPPPDAELAACHPA 669
Query: 171 LPHRDAAVAGSSPRLPSLLPPRPP 194
R A + P P PP
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPP 693
Score = 47.8 bits (112), Expect = 3e-05
Identities = 59/205 (28%), Positives = 72/205 (35%), Gaps = 49/205 (23%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTP-------------- 55
P P P PP Q P +PPA SP P S++P + P
Sbjct: 439 PFSPPPSPPV------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492
Query: 56 --ATPSGEDPPARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTS 110
ATP + PP AAP +A PP P L F G S
Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP-------FS 545
Query: 111 PSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPN 170
PS S P A +PP L+ L ++P PS +P A P
Sbjct: 546 PSASLPMS--PLATPPPQAPPVLAAPLLQVP------------PSPPASPTLQ-APRRPP 590
Query: 171 LPHRDAAVAGSSPRLPSLLPPRPPP 195
P D +V+G PRL L P PPP
Sbjct: 591 TPGPDTSVSG--PRLTLALAPGPPP 613
Score = 44.3 bits (103), Expect = 4e-04
Identities = 71/255 (27%), Positives = 98/255 (38%), Gaps = 33/255 (12%)
Query: 8 LRPSEPAPQPPEGRTLQGQLPGAPPAQRA---GSPP-DAPGSESPALACSTPATPSGEDP 63
L P P+ PP +TL P PP+Q GSP A S P+ S ATP + P
Sbjct: 340 LAPPSPSA-PPSLQTLPSP-PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397
Query: 64 PARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSE- 119
PA A P P PPA P L + + Q + P VQ+
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-----SPPPSPPVQAPF 452
Query: 120 --------GPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNL 171
P A S +PP L+ ++P S +S SPS+ P + ++P L
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP--ASPPMSPSATPPPQAPPPLAAPPL 510
Query: 172 ----PHRDAAVAGSSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLL 227
P A A ++P L +L P P S + +A+ S LA +A P+L
Sbjct: 511 QLAKPPPQAPPALATPPLQAL----PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566
Query: 228 VRAHSSLGPGRPRSP 242
+ P P SP
Sbjct: 567 AAPLLQVPPSPPASP 581
Score = 33.9 bits (76), Expect = 0.48
Identities = 58/238 (24%), Positives = 75/238 (31%), Gaps = 54/238 (22%)
Query: 20 GRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPP------------ARA 67
G T+ P A P + AG+ P S PA A P+ P R
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 68 API-----------------APRPPARPRLERALSLDDKG--------WRRRRFRGSQED 102
P+ A P R L D G RR R + +
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 103 LEARNGTSPSRGSVQSEGP-----GAPAHSCSPPCLSTSLQEIPKSRGVLSSERG-SPSS 156
+ +R +EGP A HS + P S + + P + G L S SS
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAARRRPSAGGGLQRPASRSLSS 244
Query: 157 GGNPLSGVASSSPNLPHRDAAVAGSSP---------RLPSLLPPRPPPALSLDIASDS 205
PLS A S P+ A A S R P + PPR A +L S S
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 51.6 bits (122), Expect = 2e-06
Identities = 59/211 (27%), Positives = 79/211 (37%), Gaps = 48/211 (22%)
Query: 2 PSKAENLRP-SEPAPQPPEG---RTLQGQL--PGAPPAQRAGSPPDAPGSESPALACSTP 55
P + L P + P+PQ P LQ P +PP Q SPP +P S
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-------PVSPS 424
Query: 56 ATPSGEDPPARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPS 112
ATP + PP+ AAP + P PPA P + + + T P
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPM------------------------SPSATPPP 460
Query: 113 RGSVQSEGPG---APAHSCSPPCLST-SLQEIPKSRGVLSSERGSPSSGGNPLSGVASSS 168
+ P A +PP L+T LQ +P + S P+S +A+
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520
Query: 169 PNLPHRDAA----VAGSSPRLPSLLPPRPPP 195
P P AA V S P P+L PR PP
Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551
Score = 51.2 bits (121), Expect = 3e-06
Identities = 56/224 (25%), Positives = 85/224 (37%), Gaps = 29/224 (12%)
Query: 1 MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDA------PGSESPALACST 54
+P A + RP P P + + + P+ A P A P S S + + +
Sbjct: 180 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 239
Query: 55 PATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRG 114
++P+ P AR P AP P++P+ KG + R + R +P+ G
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPK--------PKGLQALR---PPQVTPPRKDAAPALG 288
Query: 115 SVQSEGPGAPAHSCSP-PCLSTSLQEIPKSRGVLSSER----GSPSSGGN-------PLS 162
+ S P+ S P P SLQ +P S+ GSP+ PLS
Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 348
Query: 163 GVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPALSLDIASDSL 206
+A+ P P A +P P PP P A A ++L
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392
Score = 49.3 bits (116), Expect = 1e-05
Identities = 62/204 (30%), Positives = 78/204 (38%), Gaps = 25/204 (12%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPP-----DAPGSESPALACSTPA 56
P A L+ ++P PQ P PP Q SPP AP S S +L S A
Sbjct: 465 PLAAPPLQLAKPPPQAPPALA-------TPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 57 TPSGEDPPARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNG--TSP 111
TP + PP AAP + P PPA P L+ G G + L G P
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-PDTSVSGPRLTLALAPGPPPPP 576
Query: 112 SRG-SVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPN 170
SR S GP HS S +TS E + RG S G ++ P + +A+ P
Sbjct: 577 SRSPSSTLSGPDLAGHSSS----ATSTPE--ELRGYDSGPEGGAAASPPPDAELAACHPA 630
Query: 171 LPHRDAAVAGSSPRLPSLLPPRPP 194
R A + P P PP
Sbjct: 631 AWSRGPAPPLAFRGAPGAPLPWPP 654
Score = 45.4 bits (106), Expect = 2e-04
Identities = 64/231 (27%), Positives = 89/231 (38%), Gaps = 26/231 (11%)
Query: 33 AQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAPIAPRPPAR-PR------LERALS 85
A+R S P PG+ SPA+A + A + P A PRPP PR E + +
Sbjct: 151 ARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 209
Query: 86 LDDKGWRRRRFRGSQEDLEARNG--------TSPSRGSVQSEG-PGAPAHSCSPPCLSTS 136
RRR G A +SP+R + G P APAH P
Sbjct: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKG 267
Query: 137 LQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPA 196
LQ + + + +P+ G S +A+ SP+ P +A S LPS P PP
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA-PPSLQTLPS-PPATPPSQ 325
Query: 197 LSLDIASDSLRTANKV-----DSDLADYKLRAQPLLVRAHSSLGPGRPRSP 242
+ + S +L+ + S LA +A P L P P SP
Sbjct: 326 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 376
Score = 43.9 bits (102), Expect = 5e-04
Identities = 57/208 (27%), Positives = 71/208 (34%), Gaps = 47/208 (22%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTP-------------- 55
P P P PP Q P +PPA SP P S++P + P
Sbjct: 400 PFSPPPSPPV------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453
Query: 56 --ATPSGEDPPARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTS 110
ATP + PP AAP +A PP P L F G S
Sbjct: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP-------FS 506
Query: 111 PSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPN 170
PS S P A +PP L+ L ++P PS +P A P
Sbjct: 507 PSASLPMS--PLATPPPQAPPVLAAPLLQVP------------PSPPASPTLQ-APRRPP 551
Query: 171 LPHRDAAVAGSSPRLPSLLPPRPPPALS 198
P D +V+G L P PPP+ S
Sbjct: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRS 579
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 51.6 bits (122), Expect = 2e-06
Identities = 59/213 (27%), Positives = 82/213 (38%), Gaps = 46/213 (21%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGE 61
PS+A + +P P P PP G PP + P P + P+ + P P
Sbjct: 256 PSRALDDKP--PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP--- 310
Query: 62 DPPARAAPIAPRPPA------RPRL-ERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRG 114
PP+R P P PP+ PRL +R LSL + ++P
Sbjct: 311 PPPSRPGP-PPLPPSSSGNDETPRLPQRNLSL--------------------SSSTPPLP 349
Query: 115 SVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHR 174
S GP P S PP +++ P G L P S S ++P LP R
Sbjct: 350 SPGRSGPLPPPPSERPP---PPVRDPPGRSGPLPPP--PPVSRNGSTSRALPATPQLPSR 404
Query: 175 ---DAAVAGSSPRLP-----SLLPPRPPPALSL 199
D+ +G P LP + PP PPP+ S+
Sbjct: 405 SGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSI 437
Score = 39.3 bits (90), Expect = 0.011
Identities = 55/200 (27%), Positives = 70/200 (35%), Gaps = 56/200 (28%)
Query: 9 RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
R P P PP +G G +++ +P S P L P TPS RA
Sbjct: 211 RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPL----PPTPS------RAL 260
Query: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSP----SRGSVQSEGPGAP 124
P PP P G R R + +N P R S S+ P P
Sbjct: 261 DDKPPPPPPP----------VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310
Query: 125 AHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPR 184
PP +P PSS GN +P LP R+ +++ S+P
Sbjct: 311 -----PPPSRPGPPPLP------------PSSSGN------DETPRLPQRNLSLSSSTPP 347
Query: 185 LPS-----LLPP----RPPP 195
LPS LPP RPPP
Sbjct: 348 LPSPGRSGPLPPPPSERPPP 367
Score = 35.8 bits (81), Expect = 0.13
Identities = 48/189 (25%), Positives = 64/189 (33%), Gaps = 46/189 (24%)
Query: 11 SEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSES-PALACSTPATPSGEDPPARAAP 69
S P PP GR+ + P +PP+ P +PG S P P D ++
Sbjct: 124 SRPPLLPPGGRSTSAK-PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS 182
Query: 70 IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCS 129
I P P+ PR + G+ P G GP P+ +
Sbjct: 183 IPPPVPSTPR-------------------PIQSSPHNRGSPPVPG-----GPRQPSPGPT 218
Query: 130 PPCLSTSLQEIPKSRGVL---SSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLP 186
PP P +RG S R SP S +P S + P LP + P
Sbjct: 219 PP-------PFPGNRGTALGGGSIRQSPLSSSSPFS----NRPPLPPTPSRALDDKP--- 264
Query: 187 SLLPPRPPP 195
PP PPP
Sbjct: 265 ---PPPPPP 270
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 51.6 bits (122), Expect = 2e-06
Identities = 59/213 (27%), Positives = 82/213 (38%), Gaps = 46/213 (21%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGE 61
PS+A + +P P P PP G PP + P P + P+ + P P
Sbjct: 256 PSRALDDKP--PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP--- 310
Query: 62 DPPARAAPIAPRPPA------RPRL-ERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRG 114
PP+R P P PP+ PRL +R LSL + ++P
Sbjct: 311 PPPSRPGP-PPLPPSSSGNDETPRLPQRNLSL--------------------SSSTPPLP 349
Query: 115 SVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHR 174
S GP P S PP +++ P G L P S S ++P LP R
Sbjct: 350 SPGRSGPLPPPPSERPP---PPVRDPPGRSGPLPPP--PPVSRNGSTSRALPATPQLPSR 404
Query: 175 ---DAAVAGSSPRLP-----SLLPPRPPPALSL 199
D+ +G P LP + PP PPP+ S+
Sbjct: 405 SGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSI 437
Score = 39.3 bits (90), Expect = 0.011
Identities = 55/200 (27%), Positives = 70/200 (35%), Gaps = 56/200 (28%)
Query: 9 RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
R P P PP +G G +++ +P S P L P TPS RA
Sbjct: 211 RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPL----PPTPS------RAL 260
Query: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSP----SRGSVQSEGPGAP 124
P PP P G R R + +N P R S S+ P P
Sbjct: 261 DDKPPPPPPP----------VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310
Query: 125 AHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPR 184
PP +P PSS GN +P LP R+ +++ S+P
Sbjct: 311 -----PPPSRPGPPPLP------------PSSSGN------DETPRLPQRNLSLSSSTPP 347
Query: 185 LPS-----LLPP----RPPP 195
LPS LPP RPPP
Sbjct: 348 LPSPGRSGPLPPPPSERPPP 367
Score = 35.8 bits (81), Expect = 0.13
Identities = 48/189 (25%), Positives = 64/189 (33%), Gaps = 46/189 (24%)
Query: 11 SEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSES-PALACSTPATPSGEDPPARAAP 69
S P PP GR+ + P +PP+ P +PG S P P D ++
Sbjct: 124 SRPPLLPPGGRSTSAK-PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS 182
Query: 70 IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCS 129
I P P+ PR + G+ P G GP P+ +
Sbjct: 183 IPPPVPSTPR-------------------PIQSSPHNRGSPPVPG-----GPRQPSPGPT 218
Query: 130 PPCLSTSLQEIPKSRGVL---SSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLP 186
PP P +RG S R SP S +P S + P LP + P
Sbjct: 219 PP-------PFPGNRGTALGGGSIRQSPLSSSSPFS----NRPPLPPTPSRALDDKP--- 264
Query: 187 SLLPPRPPP 195
PP PPP
Sbjct: 265 ---PPPPPP 270
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 51.6 bits (122), Expect = 2e-06
Identities = 52/210 (24%), Positives = 69/210 (32%), Gaps = 27/210 (12%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQG---QLPGAPPAQRAGSPPDAPGSESPALACSTPATP 58
P + N P P P+G QG + P +PP + G PP G P P P
Sbjct: 61 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ--GGNQPQGPPPPPGKP 118
Query: 59 SGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPS------ 112
G P P P PP +P + DK R G + + G P
Sbjct: 119 QGPPPQGGNRPQGPPPPGKP--QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 176
Query: 113 --------RGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGV 164
+G + +GP P PP + S+ +G P GGN G
Sbjct: 177 GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSR---SSQSPPGKPQGPPPQGGNQPQG- 232
Query: 165 ASSSPNLPHRDAAVAGSSPRLPSLLPPRPP 194
P P G+ P+ P PP P
Sbjct: 233 PPPPPGKPQGPPPQGGNKPQGPP--PPGKP 260
Score = 44.3 bits (103), Expect = 4e-04
Identities = 45/187 (24%), Positives = 59/187 (31%), Gaps = 43/187 (22%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPP--AQRAGSPPDAPGSESPALACSTPATPSGEDPPARA 67
P +P PP+G G+ P PP + G PP S S S P P G P
Sbjct: 176 PGKPQGPPPQG----GKKPQGPPPPGKPQGPPPQGDKSRSSQ---SPPGKPQGPPPQGGN 228
Query: 68 APIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHS 127
P P PP + P +G + +GP P
Sbjct: 229 QPQGPPPP----------------------------PGKPQGPPPQGGNKPQGPPPPGKP 260
Query: 128 CSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPS 187
PP S + +R +G P GN G + P + A P+
Sbjct: 261 QGPPAQGGSKSQ--SARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ--- 315
Query: 188 LLPPRPP 194
PPRPP
Sbjct: 316 -GPPRPP 321
Score = 39.7 bits (91), Expect = 0.009
Identities = 47/185 (25%), Positives = 59/185 (31%), Gaps = 30/185 (16%)
Query: 32 PAQRAGSP--PDAPGSESPALACSTPATPSGEDPPARAAPIAPRPPARPRLERALSLDDK 89
P+ AG+P P G P P P G P P P PP +P + DK
Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--QGPPPQGDK 86
Query: 90 GWRRRRFRGSQEDLEARNGTSPS--------------RGSVQSEGPGAPAHSCSPPCLST 135
R G + + G P +G + +GP P PP
Sbjct: 87 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP---- 142
Query: 136 SLQEIPKSRGVLS---SERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPR--LPSLLP 190
+ KSR S +G P GGN G P P G P+ P P
Sbjct: 143 --PQGDKSRSPRSPPGKPQGPPPQGGNQPQG-PPPPPGKPQGPPPQGGKKPQGPPPPGKP 199
Query: 191 PRPPP 195
PPP
Sbjct: 200 QGPPP 204
Score = 34.3 bits (77), Expect = 0.37
Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 10/82 (12%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQG----QLPGAPPAQRAGSPPDAPGSESPALACSTPAT 57
P + N P P P+G QG Q +PP + G PP G+ P
Sbjct: 244 PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQG-PPQQEGNNPQG-----PPP 297
Query: 58 PSGEDPPARAAPIAPRPPARPR 79
P+G +P AP A +P PR
Sbjct: 298 PAGGNPQQPQAPPAGQPQGPPR 319
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 51.2 bits (121), Expect = 3e-06
Identities = 63/206 (30%), Positives = 77/206 (37%), Gaps = 35/206 (16%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPPAQR--AGSPPDAPGSESPALACSTPATPSGEDPPARA 67
P P PP R +PP QR + SPP + SP A+PS PP R
Sbjct: 577 PRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPS--PPPKRR 634
Query: 68 APIAPRPPARP---RLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAP 124
+P P R R+ SL K R+ S+ EAR+ P++ S P AP
Sbjct: 635 VSHSPPPKQRSSPVTKRRSPSLSSK--HRKGSSPSRSTREARS-PQPNKRHSPSPRPRAP 691
Query: 125 AHSCSPPCLSTSLQEIPKSRGVLSS--ERGSPSSGGNPLSGV------------ASSSPN 170
S SPP P RG SS R SPS P+ V AS SP
Sbjct: 692 QTSSSPP---------PVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ 742
Query: 171 LPHR--DAAVAGSSPRLPSLLPPRPP 194
R + SP + PP PP
Sbjct: 743 SVRRVSSSRSVSGSPEPAAKKPPAPP 768
Score = 39.7 bits (91), Expect = 0.009
Identities = 54/208 (25%), Positives = 80/208 (38%), Gaps = 42/208 (20%)
Query: 9 RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
RPS PA PP+ R +P Q++ + S SP G + +
Sbjct: 400 RPSPPATPPPKTR-------HSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS 452
Query: 69 PIAPRPPARPRLERALSLDDKGWR---------RRRFRGSQEDLEARNGTS-------PS 112
P AP+P ++E + S +DKG + RR++R + + +G+S P
Sbjct: 453 P-APKP---RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508
Query: 113 RGSVQSEGPG-----APAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASS 167
R V++ G +P+ S SP + P+ R R SPS P S
Sbjct: 509 RSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR-----RRRSPSP--PPTRRRRSP 561
Query: 168 SPNLPHRDAAVAGSSPRLPSLLPPRPPP 195
SP P R PR + P PPP
Sbjct: 562 SPAPPPRRRRTPTPPPRRRT---PSPPP 586
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 50.8 bits (120), Expect = 4e-06
Identities = 46/188 (24%), Positives = 59/188 (31%), Gaps = 9/188 (4%)
Query: 10 PSEPAPQPPEGRT-LQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
P+ PA PP + L P P A +PP G + P TP+ P +
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPA-HS 127
P P P A KG A SP G GAP +
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA 1268
Query: 128 CSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPS 187
+PP L L P + PS G P + +P P ++P P
Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP-------AATPPSPK 1321
Query: 188 LLPPRPPP 195
P PPP
Sbjct: 1322 GSPGTPPP 1329
Score = 48.1 bits (113), Expect = 2e-05
Identities = 61/275 (22%), Positives = 89/275 (32%), Gaps = 36/275 (13%)
Query: 10 PSEPAPQPPEGRT-LQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
P+ PA PP + L P P A +PP G + P TP+ P +
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254
Query: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSC 128
P P P P A KG + SP G S GAP
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314
Query: 129 SPPCLSTSLQEIPKSRGVLS-------SERG-------SPSSGGNPLS------------ 162
+ P P +G + S +G +PSS G P +
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374
Query: 163 -----GVASSSPNLPHRDAAVAG--SSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSD 215
G + +P P R A+ P P+++P P A + + + T +K D
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK--GD 1432
Query: 216 LADYKLRAQPLLVRAHSSLGPGRPRSPLACDDCSL 250
L + L +S G P +P + D +L
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Score = 47.8 bits (112), Expect = 3e-05
Identities = 46/188 (24%), Positives = 61/188 (32%), Gaps = 5/188 (2%)
Query: 10 PSEPAPQPPEGRTLQGQ-LPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
P+ PA PP + P P A +PP G + P TP+ P +
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139
Query: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSC 128
P P P A KG A SP G GAP
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
Query: 129 SPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSP-NLPHRDAAVAGSSPRLPS 187
+ P P +G ++ +P S P G+A+ SP P AA S P+
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSPKGGPA 1256
Query: 188 LLPPRPPP 195
PP+ P
Sbjct: 1257 TPPPKGAP 1264
Score = 46.2 bits (108), Expect = 9e-05
Identities = 64/273 (23%), Positives = 97/273 (35%), Gaps = 51/273 (18%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPPAQRAG--SPPDAPGSESPALACSTPATPSGEDPPARA 67
P+ PA PP + LP P+ + G +P G PA S P+ P +
Sbjct: 1333 PTPPAVTPPSPKGTP-TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391
Query: 68 APIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHS 127
P P P P + L K + + +PS+G +
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPK-------KAPATPVTREGAATPSKGDL----------- 1433
Query: 128 CSPPCLS-TSLQEIPKSRGVLSSERG---SPSSGGNP-LSGVASSSPNLPHRDAAVAGSS 182
+PP ++ SL++ P + S+ +G +PSS G+P L V SP P VA SS
Sbjct: 1434 -TPPAVTPVSLKKAPAT----SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488
Query: 183 --------------PRLPSLLP------PRPPPALSLDIASDSLRTANKVDSDLADYKLR 222
P LP+++P P P + IA + + K + LA +
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548
Query: 223 AQPLLVRAHSSLGPGRPRSPLACDDCSLRSAKS 255
P + P P A S + A S
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581
Score = 44.7 bits (104), Expect = 3e-04
Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 25/195 (12%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPA---- 65
P P P+G LP P A + P G + TP+ PPA
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA------TPSLKGAPTPPAATPP 1088
Query: 66 --RAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGA 123
+ P P P P A KG A SP G GA
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 124 PAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSP 183
P + P P +G ++ +P S P G+A+ SP +P
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPSPK----------GAP 1195
Query: 184 RLPSLLPPRPPPALS 198
P+ PP P L+
Sbjct: 1196 TTPAATPPSPKGGLA 1210
Score = 44.3 bits (103), Expect = 4e-04
Identities = 51/214 (23%), Positives = 66/214 (30%), Gaps = 25/214 (11%)
Query: 10 PSEPAPQPPEGRT-LQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
P+ PA PP + L P P A +PP G + P TP+ P +
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185
Query: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSC 128
P P P A KG A SP G GAP
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245
Query: 129 SPPCLSTSLQEIPKSRGVLSSERGSPSS--GG------------------NPLSGVASSS 168
+ P P +G + +P S GG +P G A+S
Sbjct: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305
Query: 169 P-NLPHRDAAVAGSSPRLPSLLPPR---PPPALS 198
P P AA S P PP+ PPA++
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339
Score = 40.0 bits (92), Expect = 0.007
Identities = 47/185 (25%), Positives = 59/185 (31%), Gaps = 29/185 (15%)
Query: 13 PAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAPIAP 72
PA P+G PPA SP P + SP A P P+ P + P P
Sbjct: 931 PASPSPKGAP-------TPPAATPPSPKGGPATPSPKWA---PTPPAATPPSPKGGPATP 980
Query: 73 RPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPPC 132
P P A KG A SP G+PA + P
Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK---------GSPAATPFPKG 1031
Query: 133 LSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSS----PRLPSL 188
ST P S +GSP++ P + + LP A S P P+
Sbjct: 1032 ASTPPAATP------PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 189 LPPRP 193
PP P
Sbjct: 1086 TPPSP 1090
Score = 39.3 bits (90), Expect = 0.011
Identities = 53/226 (23%), Positives = 72/226 (31%), Gaps = 31/226 (13%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGS----ESPALACST--- 54
PS PS P P+G TL + P P + P + ++PAL+ ++
Sbjct: 859 PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918
Query: 55 ------------PATPS---GEDPPA------RAAPIAPRPPARPRLERALSLDDKGWRR 93
PA+PS PPA + P P P P A KG
Sbjct: 919 KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978
Query: 94 RRFRGSQEDLEARNGTSPSRGSVQSEGPGAPA-HSCSPPCLSTSLQEIPKSRGVLSSERG 152
A SP G GAP + +PP S P +G +
Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA 1038
Query: 153 SPSS--GGNPLSGVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPA 196
+P S G + + +P P P PSL PPA
Sbjct: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084
Score = 35.0 bits (79), Expect = 0.21
Identities = 45/202 (22%), Positives = 68/202 (33%), Gaps = 29/202 (14%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAP 69
P E + P + QG +P + +PP G+ +P+ TP +P G P + P
Sbjct: 830 PVEASFLPENSLSFQGS-KDSPATTHSPTPPSPKGAPTPSAV--TPLSPKGVTLPPKETP 886
Query: 70 I-----------APRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQS 118
P PA P+ ALS+ ++ R T +G S
Sbjct: 887 TPSVVNLPFPKEGPATPA-PKQAPALSMTSSSPKKAR------------ATPAPKGIPAS 933
Query: 119 EGP-GAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSG-GNPLSGVASSSPNLPHRDA 176
P GAP + P P + + +P S G P + +P P
Sbjct: 934 PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
Query: 177 AVAGSSPRLPSLLPPRPPPALS 198
P PS PPA++
Sbjct: 994 PSPKGGPATPSPKGAPTPPAVT 1015
Score = 34.3 bits (77), Expect = 0.37
Identities = 53/228 (23%), Positives = 84/228 (36%), Gaps = 50/228 (21%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPAT---- 57
P KA P+ P + +G L PPA S AP + +P +TP++
Sbjct: 1412 PKKA----PATPVTREGAATPSKGDL--TPPAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465
Query: 58 -------PSGEDPPA----------RAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQ 100
PS ++PPA + AP P P P L + K
Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK-------EVPA 1518
Query: 101 EDLEARNGTSPSRGSVQSEGPG--APAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGG 158
R+ +P+ + + P AP + PP ++ PK + + + +P++
Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV---PSPKKTPAIPTPKEAPAT-- 1573
Query: 159 NPLSGVASSSPNLPHRDAAVAGSSPRL---PSLLPPRP-----PPALS 198
P S ASS P + A S L P++ P P PPA++
Sbjct: 1574 -PSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
Score = 33.1 bits (74), Expect = 0.81
Identities = 29/123 (23%), Positives = 45/123 (36%), Gaps = 9/123 (7%)
Query: 31 PPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAAPIAPRPPARPRLERALSLDDKG 90
PPA SP P +P A +TP++ PPA P+ L ++
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609
Query: 91 WRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSE 150
+ A SP +G G P SPP +SL++ P S ++ +
Sbjct: 1610 PK------EAPTPPAVTPPSPEKGPATPAPKGTPT---SPPVTPSSLKDSPTSPASVTCK 1660
Query: 151 RGS 153
G+
Sbjct: 1661 MGA 1663
Score = 33.1 bits (74), Expect = 0.81
Identities = 59/230 (25%), Positives = 86/230 (37%), Gaps = 45/230 (19%)
Query: 2 PSKAENL-RPSEPAPQPPEGRTLQGQLPGAP--------PAQRAGSPPDAPGS-----ES 47
PS E L P+ +P P E T P +P P SPP P S S
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS 1653
Query: 48 PA-LACSTPAT--PSGEDPPARAAP-------IAPRPPARPRLERALSLDDKGWRRRRFR 97
PA + C AT + + PA+ P +AP P + P + KG + ++
Sbjct: 1654 PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR---KGPQTKKSS 1710
Query: 98 GSQE----DLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGS 153
+ D A+NG S+G + + P AP T+ K + S +G
Sbjct: 1711 ATSPPICPDPSAKNG---SKGPLSTVAP-APLLPVQKDSSKTA-----KGKDASHSPKGP 1761
Query: 154 ----PSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPALSL 199
S PL+ A LP ++A ++P P LP P P +L
Sbjct: 1762 LAPPESKASTPLTAAAFEKV-LPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
Score = 32.0 bits (71), Expect = 1.8
Identities = 46/192 (23%), Positives = 72/192 (37%), Gaps = 43/192 (22%)
Query: 46 ESPALACS-TPATPSGEDPPARAAPIAPR----PPAR--------------------PRL 80
+SPA S TP +P G P+ P++P+ PP P+
Sbjct: 848 DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 81 ERALSLDDKGWRRRRFRGSQEDLEA----RNGTSPSRGSVQSE--GPGAPAHSCSP-PCL 133
ALS+ ++ R + + + A + +P + S GP P+ +P P
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967
Query: 134 STSLQEIPKSRGVLSSERGSP----SSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPSLL 189
+T PK S +G+P ++ +P G A+ SP AV SP+
Sbjct: 968 AT--PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025
Query: 190 PPRP-----PPA 196
P P PPA
Sbjct: 1026 TPFPKGASTPPA 1037
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 50.4 bits (119), Expect = 5e-06
Identities = 73/262 (27%), Positives = 101/262 (38%), Gaps = 49/262 (18%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGS--------PPDAPGSESPALACS 53
P + LRP + P + G L +P A + S PPD + PA
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP 333
Query: 54 TP--ATPSGEDPPARAAPIA----PRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARN 107
+P ATP PP+ +AP + P PPA P + S+
Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT-------------------- 373
Query: 108 GTSPSRG--SVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVA 165
T P + S+Q+ P HS + P L + P S LSS + + S G L
Sbjct: 374 -TPPMQAPPSLQTIPPIQVPHSLTSPSL-----QAPPSPLALSSLQATTSLGSPTLQATH 427
Query: 166 SSSPNLPHRDAAVAGSSPRLPSLLPPRPPP---ALSLDIASDSLRTANKVDSDLADYKLR 222
S P R + +SP P+ PP PP LSL AS L+T+ L
Sbjct: 428 SFLTMSP-RQTQASLTSPSRPASTPPDSPPLQAPLSLP-ASPPLQTSLSPAVSPLSSPLT 485
Query: 223 AQPLLVRAHSSLGPGRPRSPLA 244
PL +A SSL P++PL+
Sbjct: 486 IHPL--QALSSLASHSPQAPLS 505
Score = 47.8 bits (112), Expect = 3e-05
Identities = 65/207 (31%), Positives = 80/207 (38%), Gaps = 28/207 (13%)
Query: 2 PSKAENLRPSEPAPQPPEGRTLQGQLPGA---PPAQRAGSPP-----DAPGSESPALACS 53
PS +L P P +PP Q P A PP Q SPP AP S S +L S
Sbjct: 770 PSPPASL-PMSPLAKPPP------QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822
Query: 54 TPATPSGEDPPARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNG-- 108
ATP + PP AAP + P PPA P L+ G G + L G
Sbjct: 823 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-PDTSVSGPRLTLALAPGPP 881
Query: 109 TSPSRG-SVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASS 167
PSR S GP HS S +TS E + RG S G ++ P + +A+
Sbjct: 882 PPPSRSPSSTLSGPDLAGHSSS----ATSTPE--ELRGYDSGPEGGAAASPPPDAELAAC 935
Query: 168 SPNLPHRDAAVAGSSPRLPSLLPPRPP 194
P R A + P P PP
Sbjct: 936 HPAAWSRGPAPPLAFRGAPGAPLPWPP 962
Score = 47.0 bits (110), Expect = 5e-05
Identities = 70/271 (25%), Positives = 104/271 (38%), Gaps = 52/271 (19%)
Query: 2 PSKAENLRP-SEPAPQPPEG---RTLQGQL--PGAPPAQRAGSPPDAPGSESPALACSTP 55
P + L P + P+PQ P LQ P +PP Q SPP +P S
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-------PVSPS 688
Query: 56 ATPSGEDPPARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARN-GTSP 111
ATP + PP+ AAP + P PPA P + + + + + L A P
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ---------APPPLAAPPLQVPP 739
Query: 112 SRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSP-- 169
S + P A PP L+ ++P S +S SP + P + A ++P
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP--ASLPMSPLAKPPPQAPPALATPPL 797
Query: 170 -NLPHRDAAVAGSSPRLPSLL---------PPRPPPALSLDI--------ASDSLRTANK 211
LP A+ G +P PS PP+ PP L+ + AS +L+ +
Sbjct: 798 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 857
Query: 212 VDSDLADYKLRAQPLLVRAHSSLGPGRPRSP 242
+ D + L + +L PG P P
Sbjct: 858 PPTPGPDTSVSGPRLTL----ALAPGPPPPP 884
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/270 (24%), Positives = 95/270 (35%), Gaps = 42/270 (15%)
Query: 1 MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDA------PGSESPALACST 54
+P A + RP P P + + + P+ A P A P S S + + +
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 55 PATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRG 114
++P+ P AR P AP P++P+ KG + L T P +
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPK--------PKG---------LQALRPPQVTPPRKD 291
Query: 115 SVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHR 174
+ + GP LS+S P G + P + PL SP L
Sbjct: 292 AAPALGP-----------LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA-T 339
Query: 175 DAAVAGSSPRLPSLLPPRP-PPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSS 233
+A SP P L P PPA A S+ T A L+ P + HS
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM----QAPPSLQTIPPIQVPHSL 395
Query: 234 LGPG--RPRSPLACDDCSLRSAKSSFSLLA 261
P P SPLA ++ S +L A
Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQA 425
Score = 43.5 bits (101), Expect = 6e-04
Identities = 60/238 (25%), Positives = 80/238 (33%), Gaps = 63/238 (26%)
Query: 10 PSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTP-------------- 55
P P P PP Q P +PPA SP P S++P + P
Sbjct: 664 PFSPPPSPPV------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 56 --ATPSGEDPPARAAP---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTS 110
ATP + PP AAP + P PPA P + + + + Q
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ--------VP 769
Query: 111 PSRGSVQSEGPGAPAHSCSPPCLSTS-LQEIPKSRGVLSSERGSPSSGGNPLSGVASSSP 169
PS + P A +PP L+T LQ +P + S P+S +A+ P
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 170 NLPHRDAA----VAGSSPRLPSLLPPR-------------------------PPPALS 198
P AA V S P P+L PR PPP+ S
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887
Score = 42.7 bits (99), Expect = 0.001
Identities = 72/280 (25%), Positives = 100/280 (35%), Gaps = 39/280 (13%)
Query: 10 PSEPAPQPPEG-RTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
PS PPE ++ P APPA SPP G SP L S ATP + PP A
Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPA--LASPP-LQGLPSPPL--SPLATPPPQAPPXLAL 627
Query: 69 P---IAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSE------ 119
P P PPA P L + + Q + P VQ+
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-----SPPPSPPVQAPFSPPAS 682
Query: 120 ---GPGAPAHSCSPPCLSTSLQEIPKSRGV---LSSERGSPSSGGNPLSGVASSSPNLPH 173
P A S +PP L+ ++P S +S P PL+ P P
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP 742
Query: 174 RDAAVAGSS---PRLPSLL-------PPRPPPALSLDIASDSLRTANKVDSDLADYKLRA 223
++ S+ PR+P LL PP PP +L + S + + LA L+A
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM---SPLAKPPPQAPPALATPPLQA 799
Query: 224 QPLLVRAHSSLGPGRPRSPLACDDCSLRSAKSSFSLLAPI 263
P + P P + L + ++ L AP+
Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839
Score = 37.4 bits (85), Expect = 0.043
Identities = 56/218 (25%), Positives = 71/218 (32%), Gaps = 45/218 (20%)
Query: 31 PPAQRAGSPPDAPGSESPALAC----STPATPSGEDPPARAAPIAPRPPARPRLERALSL 86
PP Q A +P P E+P P +P PP + IA PP P + L
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603
Query: 87 DDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGV 146
+ SP + + P AP PP LQ P
Sbjct: 604 -------------------QGLPSPPLSPLATPPPQAPPXLALPP-----LQAPP----- 634
Query: 147 LSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPALSLDIASDSL 206
S SP PLS +A+ SP P+ A +P P PP PP +
Sbjct: 635 --SPPASP-----PLSPLATPSPQAPNALAVHLLQAPFSP---PPSPPVQAPFSPPASPP 684
Query: 207 RTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPRSPLA 244
+ + A L A PL V P P SP A
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASP--PMSPSA 720
Score = 33.9 bits (76), Expect = 0.48
Identities = 58/238 (24%), Positives = 75/238 (31%), Gaps = 54/238 (22%)
Query: 20 GRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPP------------ARA 67
G T+ P A P + AG+ P S PA A P+ P R
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 68 API-----------------APRPPARPRLERALSLDDKG--------WRRRRFRGSQED 102
P+ A P R L D G RR R + +
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 103 LEARNGTSPSRGSVQSEGP-----GAPAHSCSPPCLSTSLQEIPKSRGVLSSERG-SPSS 156
+ +R +EGP A HS + P S + + P + G L S SS
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAARRRPSAGGGLQRPASRSLSS 244
Query: 157 GGNPLSGVASSSPNLPHRDAAVAGSSP---------RLPSLLPPRPPPALSLDIASDS 205
PLS A S P+ A A S R P + PPR A +L S S
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 50.1 bits (118), Expect = 6e-06
Identities = 53/207 (25%), Positives = 75/207 (36%), Gaps = 30/207 (14%)
Query: 4 KAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDP 63
+ E+++PS P+P P +Q PG PPAQ+ G PG P PA PSG
Sbjct: 290 RGESVKPSLPSPSKPP---IQQPTPGKPPAQQPGHEKSQPGPAKP------PAQPSGLTK 340
Query: 64 PARAAPIAPRPPARPRLERALSLDDKGWRR--RRFRGSQEDLEARNGTS-----PSRGSV 116
P P +PP +P G + + GS++ + G P G
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400
Query: 117 QSEGPG---APAHSCSPP---CLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPN 170
++ PG P P LQ K+ G + P G P
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG----- 455
Query: 171 LPHRDAAVAGSSPRLPSLL--PPRPPP 195
P + +A + PS L P +PPP
Sbjct: 456 -PGKTSAQQTGPTKPPSQLPGPAKPPP 481
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/138 (31%), Positives = 61/138 (44%), Gaps = 26/138 (18%)
Query: 10 PSEPAPQPPEGRTLQGQLPGA--PPAQRAGS---PPDAPGSESPALACSTPATPSGEDPP 64
P++P PQ P Q PG+ PP+Q+ GS PP PG P +P P PP
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP-----SPQQPGSTKPP 530
Query: 65 AR----AAPIAPRP-PARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSE 119
++ A P A +P PA+P +++ + GS + L+ SPS + Q
Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ-------TGSGKPLQPPT-VSPS--AKQPP 580
Query: 120 GPGAPAHSCSPPCLSTSL 137
G P C P C +T L
Sbjct: 581 SQGLPKTIC-PLCNTTEL 597
Score = 37.0 bits (84), Expect = 0.056
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 13/104 (12%)
Query: 118 SEGPGAPAHSCSPPCLSTSLQEIPKSR-----GVLSSERGSPSSGGNPLSGVASSSPNLP 172
+ G G+P+H+ P + L ++ + V+S +G P P A+ SP++
Sbjct: 26 ASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPP---AAAESPSM- 81
Query: 173 HRDAAVAGSSPRLPSLLPPRP----PPALSLDIASDSLRTANKV 212
HR + S P S PP P P LS +D+ R+ K+
Sbjct: 82 HRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKL 125
Score = 35.4 bits (80), Expect = 0.16
Identities = 38/147 (25%), Positives = 54/147 (36%), Gaps = 24/147 (16%)
Query: 3 SKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGS---PPDAPGSESPALACSTPATPS 59
+ A+ P++P Q P P PP Q+ G PP PGS P P
Sbjct: 459 TSAQQTGPTKPPSQLPG--------PAKPPPQQPGPAKPPPQQPGSAKPP-----SQQPG 505
Query: 60 GEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSE 119
PP + A P +P + S + + S A+ T P V
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP----VSQT 561
Query: 120 GPGAPAHSCSPPCLSTSLQEIPKSRGV 146
G G P PP +S S ++ P S+G+
Sbjct: 562 GSGKP---LQPPTVSPSAKQ-PPSQGL 584
Score = 35.0 bits (79), Expect = 0.21
Identities = 72/290 (24%), Positives = 104/290 (35%), Gaps = 58/290 (20%)
Query: 3 SKAENLRPSEPAPQPPEGRTLQGQLPGAP-PAQRAGS------PPDAPGSESPALACSTP 55
+ E +PA Q P G LP P P R+ S PP P P P
Sbjct: 2362 TSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPP-----PP 2416
Query: 56 ATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGS 115
P PP P +P+P P+ + ++ + L T +
Sbjct: 2417 PPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVT---------TATPLFDAVTTLETTAV 2467
Query: 116 VQSEG-PGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHR 174
++S G P + +PP + IP G++ + R PS P P LP
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKPSSIPS--GLVFTHRPEPS---KPPIAPKPVIPQLP-- 2520
Query: 175 DAAVAGSSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSL 234
++ + P+ + P+ P LSL S T N V S ADYKL + + HS+
Sbjct: 2521 ------TTTQKPTDIHPK-PTGLSL----TSSMTLNLVTS--ADYKLPSPTSPLSPHSNK 2567
Query: 235 GPGR--------------PRSPLACDDCSLRSAKSSFSLLAPIRSKDVRS 270
R P P D S A +S+ L +P SKD+ S
Sbjct: 2568 SSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSP--SKDLVS 2615
Score = 33.1 bits (74), Expect = 0.81
Identities = 53/218 (24%), Positives = 76/218 (34%), Gaps = 45/218 (20%)
Query: 2 PSKAENLRPSEPAPQPPEGRTL-----QGQLPGA--PPAQRAGS--PPDAP-GSESPALA 51
P++ S+P P P + Q PG PP Q G+ PP P G P
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 52 CSTPATPSGEDPPARA---------APIAPRPPARPRLERALSLDDKGWRRRRFRGSQED 102
+ PS E P +A P PA+P ++ + + G Q
Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ----PGLQSP 430
Query: 103 LEARNGTSPSRGSVQSEGPG-APAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPL 161
+A P++ VQ GPG PA P G S+++ P+ + L
Sbjct: 431 AKA---PGPTKTPVQQPGPGKIPAQQAGP--------------GKTSAQQTGPTKPPSQL 473
Query: 162 SGVASSSPNL--PHRDAAVAGSSPRLPSLLP--PRPPP 195
G A P P + S + PS P +PPP
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511
Score = 30.4 bits (67), Expect = 5.3
Identities = 46/204 (22%), Positives = 71/204 (34%), Gaps = 15/204 (7%)
Query: 2 PSKAENLRPSEPAPQPP-EGRTLQG--QLPGAP----PAQRAGSPPDAPGSESPALACST 54
P + +P + QPP G+ +QG Q P P QR S P ++
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVK 295
Query: 55 PATPSGEDPPARAAPIAPRPPA-RPRLERALSLDDKGWRRRRFRGSQEDLEARNGT--SP 111
P+ PS PP + P +PPA +P E+ S + G + L + GT P
Sbjct: 296 PSLPSPSKPPIQ-QPTPGKPPAQQPGHEK--SQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 112 SRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNL 171
+ ++ P P PP T ++ + + P G P + P
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP-- 410
Query: 172 PHRDAAVAGSSPRLPSLLPPRPPP 195
P + + P L P P
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAP 434
Score = 30.4 bits (67), Expect = 5.3
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 8/85 (9%)
Query: 3 SKAENLRPSEPAPQP-----PEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPAT 57
S+A NL + P P P Q P PP + PP + G PA A S P
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG--PPKSTGQAPPAPAKSIPVK 997
Query: 58 PSGEDPPA-RAAPIAPRPPARPRLE 81
+ P A + P A + P R E
Sbjct: 998 KETKAPAAEKLEPKAEQAPTVKRTE 1022
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 50.1 bits (118), Expect = 6e-06
Identities = 53/207 (25%), Positives = 75/207 (36%), Gaps = 30/207 (14%)
Query: 4 KAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDP 63
+ E+++PS P+P P +Q PG PPAQ+ G PG P PA PSG
Sbjct: 290 RGESVKPSLPSPSKPP---IQQPTPGKPPAQQPGHEKSQPGPAKP------PAQPSGLTK 340
Query: 64 PARAAPIAPRPPARPRLERALSLDDKGWRR--RRFRGSQEDLEARNGTS-----PSRGSV 116
P P +PP +P G + + GS++ + G P G
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400
Query: 117 QSEGPG---APAHSCSPP---CLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPN 170
++ PG P P LQ K+ G + P G P
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG----- 455
Query: 171 LPHRDAAVAGSSPRLPSLL--PPRPPP 195
P + +A + PS L P +PPP
Sbjct: 456 -PGKTSAQQTGPTKPPSQLPGPAKPPP 481
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/138 (31%), Positives = 61/138 (44%), Gaps = 26/138 (18%)
Query: 10 PSEPAPQPPEGRTLQGQLPGA--PPAQRAGS---PPDAPGSESPALACSTPATPSGEDPP 64
P++P PQ P Q PG+ PP+Q+ GS PP PG P +P P PP
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP-----SPQQPGSTKPP 530
Query: 65 AR----AAPIAPRP-PARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSE 119
++ A P A +P PA+P +++ + GS + L+ SPS + Q
Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ-------TGSGKPLQPPT-VSPS--AKQPP 580
Query: 120 GPGAPAHSCSPPCLSTSL 137
G P C P C +T L
Sbjct: 581 SQGLPKTIC-PLCNTTEL 597
Score = 37.0 bits (84), Expect = 0.056
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 13/104 (12%)
Query: 118 SEGPGAPAHSCSPPCLSTSLQEIPKSR-----GVLSSERGSPSSGGNPLSGVASSSPNLP 172
+ G G+P+H+ P + L ++ + V+S +G P P A+ SP++
Sbjct: 26 ASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPP---AAAESPSM- 81
Query: 173 HRDAAVAGSSPRLPSLLPPRP----PPALSLDIASDSLRTANKV 212
HR + S P S PP P P LS +D+ R+ K+
Sbjct: 82 HRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKL 125
Score = 35.4 bits (80), Expect = 0.16
Identities = 38/147 (25%), Positives = 54/147 (36%), Gaps = 24/147 (16%)
Query: 3 SKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGS---PPDAPGSESPALACSTPATPS 59
+ A+ P++P Q P P PP Q+ G PP PGS P P
Sbjct: 459 TSAQQTGPTKPPSQLPG--------PAKPPPQQPGPAKPPPQQPGSAKPP-----SQQPG 505
Query: 60 GEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSE 119
PP + A P +P + S + + S A+ T P V
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP----VSQT 561
Query: 120 GPGAPAHSCSPPCLSTSLQEIPKSRGV 146
G G P PP +S S ++ P S+G+
Sbjct: 562 GSGKP---LQPPTVSPSAKQ-PPSQGL 584
Score = 35.0 bits (79), Expect = 0.21
Identities = 72/290 (24%), Positives = 104/290 (35%), Gaps = 58/290 (20%)
Query: 3 SKAENLRPSEPAPQPPEGRTLQGQLPGAP-PAQRAGS------PPDAPGSESPALACSTP 55
+ E +PA Q P G LP P P R+ S PP P P P
Sbjct: 2362 TSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPP-----PP 2416
Query: 56 ATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGS 115
P PP P +P+P P+ + ++ + L T +
Sbjct: 2417 PPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVT---------TATPLFDAVTTLETTAV 2467
Query: 116 VQSEG-PGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHR 174
++S G P + +PP + IP G++ + R PS P P LP
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKPSSIPS--GLVFTHRPEPS---KPPIAPKPVIPQLP-- 2520
Query: 175 DAAVAGSSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSL 234
++ + P+ + P+ P LSL S T N V S ADYKL + + HS+
Sbjct: 2521 ------TTTQKPTDIHPK-PTGLSL----TSSMTLNLVTS--ADYKLPSPTSPLSPHSNK 2567
Query: 235 GPGR--------------PRSPLACDDCSLRSAKSSFSLLAPIRSKDVRS 270
R P P D S A +S+ L +P SKD+ S
Sbjct: 2568 SSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSP--SKDLVS 2615
Score = 33.1 bits (74), Expect = 0.81
Identities = 53/218 (24%), Positives = 76/218 (34%), Gaps = 45/218 (20%)
Query: 2 PSKAENLRPSEPAPQPPEGRTL-----QGQLPGA--PPAQRAGS--PPDAP-GSESPALA 51
P++ S+P P P + Q PG PP Q G+ PP P G P
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 52 CSTPATPSGEDPPARA---------APIAPRPPARPRLERALSLDDKGWRRRRFRGSQED 102
+ PS E P +A P PA+P ++ + + G Q
Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ----PGLQSP 430
Query: 103 LEARNGTSPSRGSVQSEGPG-APAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPL 161
+A P++ VQ GPG PA P G S+++ P+ + L
Sbjct: 431 AKA---PGPTKTPVQQPGPGKIPAQQAGP--------------GKTSAQQTGPTKPPSQL 473
Query: 162 SGVASSSPNL--PHRDAAVAGSSPRLPSLLP--PRPPP 195
G A P P + S + PS P +PPP
Sbjct: 474 PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511
Score = 30.4 bits (67), Expect = 5.3
Identities = 46/204 (22%), Positives = 71/204 (34%), Gaps = 15/204 (7%)
Query: 2 PSKAENLRPSEPAPQPP-EGRTLQG--QLPGAP----PAQRAGSPPDAPGSESPALACST 54
P + +P + QPP G+ +QG Q P P QR S P ++
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVK 295
Query: 55 PATPSGEDPPARAAPIAPRPPA-RPRLERALSLDDKGWRRRRFRGSQEDLEARNGT--SP 111
P+ PS PP + P +PPA +P E+ S + G + L + GT P
Sbjct: 296 PSLPSPSKPPIQ-QPTPGKPPAQQPGHEK--SQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 112 SRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNL 171
+ ++ P P PP T ++ + + P G P + P
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP-- 410
Query: 172 PHRDAAVAGSSPRLPSLLPPRPPP 195
P + + P L P P
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAP 434
Score = 30.4 bits (67), Expect = 5.3
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 8/85 (9%)
Query: 3 SKAENLRPSEPAPQP-----PEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPAT 57
S+A NL + P P P Q P PP + PP + G PA A S P
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG--PPKSTGQAPPAPAKSIPVK 997
Query: 58 PSGEDPPA-RAAPIAPRPPARPRLE 81
+ P A + P A + P R E
Sbjct: 998 KETKAPAAEKLEPKAEQAPTVKRTE 1022
>gi|239752280 PREDICTED: similar to family with sequence similarity
48, member B2 [Homo sapiens]
Length = 779
Score = 48.9 bits (115), Expect = 1e-05
Identities = 53/187 (28%), Positives = 78/187 (41%), Gaps = 24/187 (12%)
Query: 1 MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPG-SESPALACSTPATPS 59
+PS + + P G L+ P A PA A +P AP + +PALA + A +
Sbjct: 429 LPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAA 488
Query: 60 GEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSE 119
G AAP + P+ P ++ + G R RF ++ R G++ + + E
Sbjct: 489 G-----GAAPSHSQKPSVPLIKASRRRPAAG-RPTRFVKIAPAIQVRTGSTGLK-ATNVE 541
Query: 120 GP--GAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPH-RDA 176
GP GA CS + V + G+P+ G SG+ SS LP R
Sbjct: 542 GPVRGAQVLGCS-------------FKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPG 588
Query: 177 AVAGSSP 183
AV SSP
Sbjct: 589 AVQASSP 595
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,291,594
Number of Sequences: 37866
Number of extensions: 1670272
Number of successful extensions: 18071
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 1330
Number of HSP's that attempted gapping in prelim test: 11416
Number of HSP's gapped (non-prelim): 5896
length of query: 644
length of database: 18,247,518
effective HSP length: 109
effective length of query: 535
effective length of database: 14,120,124
effective search space: 7554266340
effective search space used: 7554266340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.