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Search of human proteins with 38202211
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38202211 N-acetylglucosamine-1-phosphate transferase [Homo
sapiens]
(1256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38202211 N-acetylglucosamine-1-phosphate transferase [Homo sa... 2560 0.0
gi|24041035 notch 2 preproprotein [Homo sapiens] 56 2e-07
gi|134244285 Notch homolog 3 [Homo sapiens] 53 2e-06
gi|55770876 notch4 preproprotein [Homo sapiens] 51 8e-06
gi|148833508 notch1 preproprotein [Homo sapiens] 50 1e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 44 0.001
gi|60099478 keratin associated protein 5-6 [Homo sapiens] 42 0.004
gi|157739936 chromosome 10 open reading frame 68 [Homo sapiens] 38 0.053
gi|38045915 pregnancy-associated plasma protein A preproprotein ... 38 0.070
gi|60593036 keratin associated protein 5-3 [Homo sapiens] 38 0.070
gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sap... 38 0.070
gi|13994372 keratin associated protein 17-1 [Homo sapiens] 37 0.091
gi|51972220 keratin associated protein 5-2 [Homo sapiens] 37 0.091
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 37 0.12
gi|118498337 HECT domain containing 1 [Homo sapiens] 36 0.26
gi|122891874 keratin associated protein 5-5 [Homo sapiens] 35 0.35
gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens] 35 0.45
gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens] 35 0.45
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 35 0.45
gi|116174738 pappalysin 2 isoform 1 [Homo sapiens] 35 0.45
gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens] 35 0.45
gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens] 35 0.45
gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens] 35 0.45
gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens] 35 0.45
gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo sap... 35 0.45
gi|30387646 late cornified envelope 1F [Homo sapiens] 34 0.77
gi|123702038 keratin associated protein 5-9 [Homo sapiens] 34 0.77
gi|109255251 loricrin [Homo sapiens] 34 1.0
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens] 34 1.0
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 33 1.3
>gi|38202211 N-acetylglucosamine-1-phosphate transferase [Homo
sapiens]
Length = 1256
Score = 2560 bits (6635), Expect = 0.0
Identities = 1256/1256 (100%), Positives = 1256/1256 (100%)
Query: 1 MLFKLLQRQTYTCLSHRYGLYVCFLGVVVTIVSAFQFGEVVLEWSRDQYHVLFDSYRDNI 60
MLFKLLQRQTYTCLSHRYGLYVCFLGVVVTIVSAFQFGEVVLEWSRDQYHVLFDSYRDNI
Sbjct: 1 MLFKLLQRQTYTCLSHRYGLYVCFLGVVVTIVSAFQFGEVVLEWSRDQYHVLFDSYRDNI 60
Query: 61 AGKSFQNRLCLPMPIDVVYTWVNGTDLELLKELQQVREQMEEEQKAMREILGKNTTEPTK 120
AGKSFQNRLCLPMPIDVVYTWVNGTDLELLKELQQVREQMEEEQKAMREILGKNTTEPTK
Sbjct: 61 AGKSFQNRLCLPMPIDVVYTWVNGTDLELLKELQQVREQMEEEQKAMREILGKNTTEPTK 120
Query: 121 KSEKQLECLLTHCIKVPMLVLDPALPANITLKDLPSLYPSFHSASDIFNVAKPKNPSTNV 180
KSEKQLECLLTHCIKVPMLVLDPALPANITLKDLPSLYPSFHSASDIFNVAKPKNPSTNV
Sbjct: 121 KSEKQLECLLTHCIKVPMLVLDPALPANITLKDLPSLYPSFHSASDIFNVAKPKNPSTNV 180
Query: 181 SVVVFDSTKDVEDAHSGLLKGNSRQTVWRGYLTTDKEVPGLVLMQDLAFLSGFPPTFKET 240
SVVVFDSTKDVEDAHSGLLKGNSRQTVWRGYLTTDKEVPGLVLMQDLAFLSGFPPTFKET
Sbjct: 181 SVVVFDSTKDVEDAHSGLLKGNSRQTVWRGYLTTDKEVPGLVLMQDLAFLSGFPPTFKET 240
Query: 241 NQLKTKLPENLSSKVKLLQLYSEASVALLKLNNPKDFQELNKQTKKNMTIDGKELTISPA 300
NQLKTKLPENLSSKVKLLQLYSEASVALLKLNNPKDFQELNKQTKKNMTIDGKELTISPA
Sbjct: 241 NQLKTKLPENLSSKVKLLQLYSEASVALLKLNNPKDFQELNKQTKKNMTIDGKELTISPA 300
Query: 301 YLLWDLSAISQSKQDEDISASRFEDNEELRYSLRSIERHAPWVRNIFIVTNGQIPSWLNL 360
YLLWDLSAISQSKQDEDISASRFEDNEELRYSLRSIERHAPWVRNIFIVTNGQIPSWLNL
Sbjct: 301 YLLWDLSAISQSKQDEDISASRFEDNEELRYSLRSIERHAPWVRNIFIVTNGQIPSWLNL 360
Query: 361 DNPRVTIVTHQDVFRNLSHLPTFSSPAIESHIHRIEGLSQKFIYLNDDVMFGKDVWPDDF 420
DNPRVTIVTHQDVFRNLSHLPTFSSPAIESHIHRIEGLSQKFIYLNDDVMFGKDVWPDDF
Sbjct: 361 DNPRVTIVTHQDVFRNLSHLPTFSSPAIESHIHRIEGLSQKFIYLNDDVMFGKDVWPDDF 420
Query: 421 YSHSKGQKVYLTWPVPNCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYIAG 480
YSHSKGQKVYLTWPVPNCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYIAG
Sbjct: 421 YSHSKGQKVYLTWPVPNCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYIAG 480
Query: 481 GGGTGSIGVGQPWQFGGGINSVSYCNQGCANSWLADKFCDQACNVLSCGFDAGDCGQDHF 540
GGGTGSIGVGQPWQFGGGINSVSYCNQGCANSWLADKFCDQACNVLSCGFDAGDCGQDHF
Sbjct: 481 GGGTGSIGVGQPWQFGGGINSVSYCNQGCANSWLADKFCDQACNVLSCGFDAGDCGQDHF 540
Query: 541 HELYKVILLPNQTHYIIPKGECLPYFSFAEVAKRGVEGAYSDNPIIRHASIANKWKTIHL 600
HELYKVILLPNQTHYIIPKGECLPYFSFAEVAKRGVEGAYSDNPIIRHASIANKWKTIHL
Sbjct: 541 HELYKVILLPNQTHYIIPKGECLPYFSFAEVAKRGVEGAYSDNPIIRHASIANKWKTIHL 600
Query: 601 IMHSGMNATTIHFNLTFQNTNDEEFKMQITVEVDTREGPKLNSTAQKGYENLVSPITLLP 660
IMHSGMNATTIHFNLTFQNTNDEEFKMQITVEVDTREGPKLNSTAQKGYENLVSPITLLP
Sbjct: 601 IMHSGMNATTIHFNLTFQNTNDEEFKMQITVEVDTREGPKLNSTAQKGYENLVSPITLLP 660
Query: 661 EAEILFEDIPKEKRFPKFKRHDVNSTRRAQEEVKIPLVNISLLPKDAQLSLNTLDLQLEH 720
EAEILFEDIPKEKRFPKFKRHDVNSTRRAQEEVKIPLVNISLLPKDAQLSLNTLDLQLEH
Sbjct: 661 EAEILFEDIPKEKRFPKFKRHDVNSTRRAQEEVKIPLVNISLLPKDAQLSLNTLDLQLEH 720
Query: 721 GDITLKGYNLSKSALLRSFLMNSQHAKIKNQAIITDETNDSLVAPQEKQVHKSILPNSLG 780
GDITLKGYNLSKSALLRSFLMNSQHAKIKNQAIITDETNDSLVAPQEKQVHKSILPNSLG
Sbjct: 721 GDITLKGYNLSKSALLRSFLMNSQHAKIKNQAIITDETNDSLVAPQEKQVHKSILPNSLG 780
Query: 781 VSERLQRLTFPAVSVKVNGHDQGQNPPLDLETTARFRVETHTQKTIGGNVTKEKPPSLIV 840
VSERLQRLTFPAVSVKVNGHDQGQNPPLDLETTARFRVETHTQKTIGGNVTKEKPPSLIV
Sbjct: 781 VSERLQRLTFPAVSVKVNGHDQGQNPPLDLETTARFRVETHTQKTIGGNVTKEKPPSLIV 840
Query: 841 PLESQMTKEKKITGKEKENSRMEENAENHIGVTEVLLGRKLQHYTDSYLGFLPWEKKKYF 900
PLESQMTKEKKITGKEKENSRMEENAENHIGVTEVLLGRKLQHYTDSYLGFLPWEKKKYF
Sbjct: 841 PLESQMTKEKKITGKEKENSRMEENAENHIGVTEVLLGRKLQHYTDSYLGFLPWEKKKYF 900
Query: 901 QDLLDEEESLKTQLAYFTDSKNTGRQLKDTFADSLRYVNKILNSKFGFTSRKVPAHMPHM 960
QDLLDEEESLKTQLAYFTDSKNTGRQLKDTFADSLRYVNKILNSKFGFTSRKVPAHMPHM
Sbjct: 901 QDLLDEEESLKTQLAYFTDSKNTGRQLKDTFADSLRYVNKILNSKFGFTSRKVPAHMPHM 960
Query: 961 IDRIVMQELQDMFPEEFDKTSFHKVRHSEDMQFAFSYFYYLMSAVQPLNISQVFDEVDTD 1020
IDRIVMQELQDMFPEEFDKTSFHKVRHSEDMQFAFSYFYYLMSAVQPLNISQVFDEVDTD
Sbjct: 961 IDRIVMQELQDMFPEEFDKTSFHKVRHSEDMQFAFSYFYYLMSAVQPLNISQVFDEVDTD 1020
Query: 1021 QSGVLSDREIRTLATRIHELPLSLQDLTGLEHMLINCSKMLPADITQLNNIPPTQESYYD 1080
QSGVLSDREIRTLATRIHELPLSLQDLTGLEHMLINCSKMLPADITQLNNIPPTQESYYD
Sbjct: 1021 QSGVLSDREIRTLATRIHELPLSLQDLTGLEHMLINCSKMLPADITQLNNIPPTQESYYD 1080
Query: 1081 PNLPPVTKSLVTNCKPVTDKIHKAYKDKNKYRFEIMGEEEIAFKMIRTNVSHVVGQLDDI 1140
PNLPPVTKSLVTNCKPVTDKIHKAYKDKNKYRFEIMGEEEIAFKMIRTNVSHVVGQLDDI
Sbjct: 1081 PNLPPVTKSLVTNCKPVTDKIHKAYKDKNKYRFEIMGEEEIAFKMIRTNVSHVVGQLDDI 1140
Query: 1141 RKNPRKFVCLNDNIDHNHKDAQTVKAVLRDFYESMFPIPSQFELPREYRNRFLHMHELQE 1200
RKNPRKFVCLNDNIDHNHKDAQTVKAVLRDFYESMFPIPSQFELPREYRNRFLHMHELQE
Sbjct: 1141 RKNPRKFVCLNDNIDHNHKDAQTVKAVLRDFYESMFPIPSQFELPREYRNRFLHMHELQE 1200
Query: 1201 WRAYRDKLKFWTHCVLATLIMFTIFSFFAEQLIALKRKIFPRRRIHKEASPNRIRV 1256
WRAYRDKLKFWTHCVLATLIMFTIFSFFAEQLIALKRKIFPRRRIHKEASPNRIRV
Sbjct: 1201 WRAYRDKLKFWTHCVLATLIMFTIFSFFAEQLIALKRKIFPRRRIHKEASPNRIRV 1256
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 56.2 bits (134), Expect = 2e-07
Identities = 41/151 (27%), Positives = 53/151 (35%), Gaps = 51/151 (33%)
Query: 434 PVPNCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYIAGGGGTGSIGVGQPW 493
P C +DG CD+ACN+ AC WDGGDC S+ + PW
Sbjct: 1421 PPATCLSQYCADKARDGVCDEACNSHACQWDGGDC-----------------SLTMENPW 1463
Query: 494 -QFGGGINSVSYCNQGC------------------------ANSWLADKF----CDQACN 524
+ Y N C + + AD F CDQ CN
Sbjct: 1464 ANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCN 1523
Query: 525 VLSCGFDAGDCGQDHFHELYK-----VILLP 550
CG+D DC D L + V+L+P
Sbjct: 1524 SEECGWDGLDCAADQPENLAEGTLVIVVLMP 1554
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 53.1 bits (126), Expect = 2e-06
Identities = 35/136 (25%), Positives = 48/136 (35%), Gaps = 50/136 (36%)
Query: 436 PNCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYIAGGGGTGSIGVGQPWQF 495
P C + D CD+ CN+ C WDGGDC S+ VG PW+
Sbjct: 1385 PRCPRAACQAKRGDQRCDRECNSPGCGWDGGDC-----------------SLSVGDPWRQ 1427
Query: 496 GGGIN-----SVSYCNQGCAN------------------------SWLADKF----CDQA 522
+ + S C+ C++ + AD F CDQ
Sbjct: 1428 CEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQG 1487
Query: 523 CNVLSCGFDAGDCGQD 538
CN CG+D DC +
Sbjct: 1488 CNTEECGWDGLDCASE 1503
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 50.8 bits (120), Expect = 8e-06
Identities = 41/127 (32%), Positives = 47/127 (37%), Gaps = 47/127 (37%)
Query: 434 PVPNC----AEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYIAGGGGTGSIGV 489
P P C A+GC G DG CD C+ +WDGGDC S+GV
Sbjct: 1166 PGPRCQKPGAKGCEGR-SGDGACDAGCSGPGGNWDGGDC-----------------SLGV 1207
Query: 490 GQPWQFGGGINSVSYCNQGCANSWL--ADKFCDQACNVLSCGFDAGDCG----------- 536
PW+ G S S C WL D C C+ C FD DC
Sbjct: 1208 PDPWK---GCPSHSRC-------WLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQ 1257
Query: 537 --QDHFH 541
DHFH
Sbjct: 1258 YCHDHFH 1264
Score = 41.2 bits (95), Expect = 0.006
Identities = 13/25 (52%), Positives = 17/25 (68%)
Query: 449 DGYCDKACNNSACDWDGGDCSGNSG 473
+G+C+K CN + C WDGGDC G
Sbjct: 1265 NGHCEKGCNTAECGWDGGDCRPEDG 1289
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 50.4 bits (119), Expect = 1e-05
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 31/139 (22%)
Query: 435 VPNCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGS-----------RYIAGG-- 481
+P C E C CNN AC WDGGDCS N +Y + G
Sbjct: 1451 LPECQEDAGNK-----VCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHC 1505
Query: 482 ----GGTGSIGVGQPWQFGGGINSVSYCNQGCANSWLADKFCDQACNVLSCGFDAGDCGQ 537
G + G Q G + Y +Q C + + +D CDQ CN C +D DC
Sbjct: 1506 DSQCNSAGCLFDGFDCQRAEGQCNPLY-DQYCKDHF-SDGHCDQGCNSAECEWDGLDCA- 1562
Query: 538 DHFHE------LYKVILLP 550
+H E L V+L+P
Sbjct: 1563 EHVPERLAAGTLVVVVLMP 1581
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 43.9 bits (102), Expect = 0.001
Identities = 111/519 (21%), Positives = 214/519 (41%), Gaps = 60/519 (11%)
Query: 650 ENLVSPITLLPEAEILFEDIPKEKRFPKFKRHDVNSTRRAQEEVKIPLVNISLLPKDAQL 709
E L + L EAE L + +K+ + HD+ + +EE ++ K Q
Sbjct: 887 EQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEE---RCQHLQAEKKKMQQ 943
Query: 710 SLNTLDLQLEHGDITLKGYNLSKSALLRSFLMNSQHAKIKNQAIITDETNDSLVAPQEKQ 769
++ L+ QLE + + L K ++ K++ + II ++ N L A ++K
Sbjct: 944 NIQELEEQLEEEESARQKLQLEKVTT------EAKLKKLEEEQIILEDQNCKL-AKEKKL 996
Query: 770 VHKSILPNSLGVSERLQRLTFPAVSVKVNGHDQGQNPPLD--LETTARFRVETH-TQKTI 826
+ I + ++E ++ A K+ + L+ L + R E T++ +
Sbjct: 997 LEDRIAEFTTNLTEEEEKSKSLA---KLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 827 GGNVTKEKPPSLIVPLESQMTKEKKITGKEKENSRM------EENAENHIGVTEVLLGRK 880
G+ T I L++Q+ + K K++E + EE A+ ++ + ++ R+
Sbjct: 1054 EGDSTDLSDQ--IAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKI---RE 1108
Query: 881 LQHYTDSYLGFLPWEK------KKYFQDLLDEEESLKTQLAYFTDSKNTGRQLKDTFADS 934
L+ L E+ +K +DL +E E+LKT+L DS ++L+
Sbjct: 1109 LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQE 1168
Query: 935 LRYVNKILNSKFGFTSRKVPAHMPHMIDRIVMQELQDMFPEEFDKTSFHKVRHSEDMQFA 994
+ + K L + ++ A + M R + + E+ ++T K + Q
Sbjct: 1169 VNILKKTLEEE----AKTHEAQIQEM--RQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 995 FSYFYYLMSAVQPL---------NISQVFDEVDTDQSGVLSDREIRT-LATRIHELPLSL 1044
+ L + V+ L +V ++ Q +RT LA ++ +L + L
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 1045 QDLTGLEHMLINCSKMLPADITQL-NNIPPTQESYYDPNLPPVTKSLVTNCKPVTDKIHK 1103
++TGL + S L D + L + + TQE + N + SL T K V D
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKL--SLSTKLKQVED---- 1336
Query: 1104 AYKDKNKYRFEIMGEEEIAFKMIRTNVSHVVGQLDDIRK 1142
+KN +R E + EEE A + ++ + Q+ D++K
Sbjct: 1337 ---EKNSFR-EQLEEEEEAKHNLEKQIATLHAQVADMKK 1371
>gi|60099478 keratin associated protein 5-6 [Homo sapiens]
Length = 129
Score = 42.0 bits (97), Expect = 0.004
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 12/84 (14%)
Query: 452 CDKACNNSACDWDGGD--CSGNSGGSRYIAGGGGTGSIGVGQPWQFGGGINSVS-----Y 504
C AC+ ++C GG C G+ GGS+ GG GS G + G + S Y
Sbjct: 41 CVPACSCTSCGSCGGSKGCCGSCGGSK-----GGCGSCGGSKGGCGSCGCSQCSCCKPCY 95
Query: 505 CNQGCANSWLADKFCDQACNVLSC 528
C+ GC +S C C+ SC
Sbjct: 96 CSSGCGSSCCQSSCCKPCCSQASC 119
>gi|157739936 chromosome 10 open reading frame 68 [Homo sapiens]
Length = 628
Score = 38.1 bits (87), Expect = 0.053
Identities = 71/269 (26%), Positives = 119/269 (44%), Gaps = 38/269 (14%)
Query: 732 KSALLRSFLMNSQHAKIKNQAIIT--DETNDSLVAPQEKQVHKSILPNSLGVSERLQRLT 789
+ ++ +S + + +K Q IIT +E +LV + V K L + +++L R
Sbjct: 66 QDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSK--LEMQIEKTKKLPR-- 121
Query: 790 FPAVSVKVNGHDQ--GQNPPLD-LETTARFRVETHTQKTIGGNVTK-EKPPSLIVPLES- 844
+ + HD+ G+NP L ++ ++ +V+ Q+T G S+ V +S
Sbjct: 122 ----EKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSV 177
Query: 845 ---QMTKEKKIT-GKEKENSRMEENAENHIGVTEVLLGRKLQHYTDSYLG-------FLP 893
QM ++KKIT G+E+ N+R+ EN I V + KLQ + P
Sbjct: 178 SKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKS-KLQMQEKKQINSGVERHKTFP 236
Query: 894 WEKKK---YFQDLLDEEESLKTQLAYFT---DSKNTGRQLKDTFADSLRYV--NKILNSK 945
E KK + LL EE+ L ++ T +K T R K T +SLR ++LN +
Sbjct: 237 LEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSR--KKTDIESLRGALGRRLLNDE 294
Query: 946 FGFTSRKVPA-HMPHMIDRIVMQELQDMF 973
F S+ P + + D L+D F
Sbjct: 295 FKTQSKSFPGPDIEQLTDAFGRDILKDEF 323
>gi|38045915 pregnancy-associated plasma protein A preproprotein [Homo
sapiens]
Length = 1627
Score = 37.7 bits (86), Expect = 0.070
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 426 GQKVYLTWPVPNCAEGCPGSWIKDGYCDKACNNSACDWDGGDC 468
G K Y + +C +GC ++ D YCD N + C++DGGDC
Sbjct: 1542 GLKWYPHPALIHCVKGCE-PFMGDNYCDAINNRAFCNYDGGDC 1583
Score = 32.3 bits (72), Expect = 2.9
Identities = 12/32 (37%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Query: 504 YCNQGCANSWLADKFCDQACNVLSCGFDAGDC 535
+C +GC ++ D +CD N C +D GDC
Sbjct: 1553 HCVKGC-EPFMGDNYCDAINNRAFCNYDGGDC 1583
>gi|60593036 keratin associated protein 5-3 [Homo sapiens]
Length = 238
Score = 37.7 bits (86), Expect = 0.070
Identities = 26/93 (27%), Positives = 34/93 (36%), Gaps = 7/93 (7%)
Query: 438 CAEGCPGSWIKDGYCDKACNNSACDWDG-GDCSGNSGGSRYIAGG-GGTGSIGVGQPWQF 495
C GC G C +C C G C G+ G + G GG GS G Q +
Sbjct: 73 CKGGCGSCGGSKGGCGSSCCVPVCCSSSCGSCGGSKGVCGFRGGSKGGCGSCGCSQCSCY 132
Query: 496 GGGINSVSYCNQGCANSWLADKFCDQACNVLSC 528
C+ GC +S C +C+ SC
Sbjct: 133 -----KPCCCSSGCGSSCCQSSCCKPSCSQSSC 160
Score = 34.3 bits (77), Expect = 0.77
Identities = 25/85 (29%), Positives = 32/85 (37%), Gaps = 20/85 (23%)
Query: 452 CDKACNNSACDWDGGDCSGNSGGSRYIAGGGGTGSIGVGQPWQFGGGINSVSYCNQGCAN 511
C AC+ S+C G+ GGS+ + G G GG S GC +
Sbjct: 48 CVPACSCSSC--------GSCGGSKGVCGSCGGCK----------GGCGSCGGSKGGCGS 89
Query: 512 SWLADKFCDQACNVLSCGFDAGDCG 536
S C +C SCG G CG
Sbjct: 90 SCCVPVCCSSSCG--SCGGSKGVCG 112
Score = 31.6 bits (70), Expect = 5.0
Identities = 25/72 (34%), Positives = 28/72 (38%), Gaps = 12/72 (16%)
Query: 468 CSGNSGGSRYIAGGGGTGSIGVGQPWQFGGGINSVSYCNQGCANSWLADK---FCDQACN 524
CSG SGG GG G+ G G +GG C GC K C AC+
Sbjct: 3 CSGCSGGCGSSCGGCGSSCGGCGS--GYGG-------CGSGCCVPVCCCKPVCCCVPACS 53
Query: 525 VLSCGFDAGDCG 536
SCG G G
Sbjct: 54 CSSCGSCGGSKG 65
>gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo
sapiens]
Length = 1576
Score = 37.7 bits (86), Expect = 0.070
Identities = 19/59 (32%), Positives = 31/59 (52%)
Query: 700 ISLLPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFLMNSQHAKIKNQAIITDET 758
++ LP + + L L+L+L GDIT KGY +S LL + +Q Q + ++T
Sbjct: 13 VAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKELRNQT 71
>gi|13994372 keratin associated protein 17-1 [Homo sapiens]
Length = 105
Score = 37.4 bits (85), Expect = 0.091
Identities = 28/86 (32%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 437 NCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNS-GGSRYIAGGGGTGSIGVGQPWQF 495
NC E C + G C C S C G C G+ GGS + G+G G G
Sbjct: 17 NCCEEC---CCQPGCC--GCCGSCCGCGGSGCGGSGCGGSCCGSSCCGSGCGGCGGCGGC 71
Query: 496 GGGINSVSYCNQGCANSWLADKFCDQ 521
GGG S C C S C Q
Sbjct: 72 GGGCCGSSCCGSSCCGSGCCGPVCCQ 97
>gi|51972220 keratin associated protein 5-2 [Homo sapiens]
Length = 177
Score = 37.4 bits (85), Expect = 0.091
Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 10/104 (9%)
Query: 426 GQKVYLTWPVPNCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYIAGG-GGT 484
G + Y+ PV C C SW+ C + G C G+ GG G GG
Sbjct: 53 GSRCYV--PVCCCKPVC--SWVPACSCTSCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGC 108
Query: 485 GSIGVGQPWQFGGGINSVSYCNQGCANSWLADKFCDQACNVLSC 528
GS G Q C+ GC +S C C SC
Sbjct: 109 GSCGCSQ-----SSCCKPCCCSSGCGSSCCQSSCCKPCCCQSSC 147
Score = 35.0 bits (79), Expect = 0.45
Identities = 27/114 (23%), Positives = 33/114 (28%), Gaps = 28/114 (24%)
Query: 438 CAEGCPGSWIKDGYCDKACNNSA--------------------CDW-------DGGDCSG 470
C GC G G C C + C W G C G
Sbjct: 24 CGSGCGGCGSGRGGCGSGCGGCSSSCGGCGSRCYVPVCCCKPVCSWVPACSCTSCGSCGG 83
Query: 471 NSGGSRYIAGG-GGTGSIGVGQPWQFGGGINSVSYCNQGCANSWLADKFCDQAC 523
+ GG G GG GS G + G + S C C +S C +C
Sbjct: 84 SKGGCGSCGGSKGGCGSCGGSKGGCGSCGCSQSSCCKPCCCSSGCGSSCCQSSC 137
Score = 32.3 bits (72), Expect = 2.9
Identities = 29/94 (30%), Positives = 34/94 (36%), Gaps = 19/94 (20%)
Query: 452 CDKACNNSACDWDGGDCSGNSGGSRYIAGGGGTGSIGVGQPWQFGGGINSVSYCNQGC-- 509
C + C S C G C G G GG G+G G G GG +S C C
Sbjct: 6 CSRGCG-SGCGGCGSSCGGCGSG----CGGCGSGRGGCGS--GCGGCSSSCGGCGSRCYV 58
Query: 510 -------ANSWLADKFCDQACNVLSCGFDAGDCG 536
SW+ C +C SCG G CG
Sbjct: 59 PVCCCKPVCSWVPACSC-TSCG--SCGGSKGGCG 89
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
1 [Homo sapiens]
Length = 1412
Score = 37.0 bits (84), Expect = 0.12
Identities = 72/376 (19%), Positives = 141/376 (37%), Gaps = 45/376 (11%)
Query: 796 KVNGHDQGQNPPLDLETTARFRVETHTQKTIGGNVTKEKPPSLIVPLESQMTKEKKITGK 855
+ G Q QN D + E TQ+ T E+ + LES + ++KK K
Sbjct: 669 RARGEAQSQNQATDGREGGKALEEYITQERNRAKETLEEERKRMQELESLLAQQKKALAK 728
Query: 856 ---EKENSRMEENAENHIGVTEVLLGRKLQHYTDSYLGFLPWEKKKYFQDLLDEEESLKT 912
+++N E E V E L +L + + EK+K + L E+ ++
Sbjct: 729 SITQEKNRVKEALEEEQTRVQE--LEERLARQKEVLESSIAHEKRKAKEALESEKRKVQD 786
Query: 913 QLAYFTDSKNTG--------RQLKDTFADSLRYVNKILNSKFGFTSRKVPAHMPHMIDRI 964
+ T K R+ K+ + V + N T +K + + +
Sbjct: 787 LENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENR---LTKQKEELELKEQKEDV 843
Query: 965 VMQELQDMFP--EEFDKTSFHKVRHSEDMQFAFSYFYYLMSA-------------VQPLN 1009
+ +L D EE KT + +E + + + +Q
Sbjct: 844 LNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLILQQKM 903
Query: 1010 ISQVFDEVDTDQSGVLSDREIRTLATRIHELPLSLQDLTGLEHMLINCSKMLPADITQL- 1068
+ + DE ++ + G + EI +I + ++ L + K + +I L
Sbjct: 904 VKALQDEQESQRHGF--EEEIMEYKEQIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLK 961
Query: 1069 -NNIPPTQESYYDPNLPPVTKSLVTNC--KPVTDKIHKAYKDKNKYRFEIMGEEEIAFKM 1125
N+ P +E DP + P+T+S + + + D + A K EI+ ++E+ K
Sbjct: 962 DNDPAPKEERPQDPLVAPMTESSAKDMAYEHLIDDLLAAQK-------EILSQQEVIMK- 1013
Query: 1126 IRTNVSHVVGQLDDIR 1141
+R +++ ++ D+R
Sbjct: 1014 LRKDLTEAHSRMSDLR 1029
>gi|118498337 HECT domain containing 1 [Homo sapiens]
Length = 2610
Score = 35.8 bits (81), Expect = 0.26
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 7/91 (7%)
Query: 792 AVSVKVNGHDQGQNPPLDL---ETTARFRVETHTQKTIGGNVTKEKPPSLIVPLESQMTK 848
A+++KV G + L L +T + V+ Q + GNV +K + P + M +
Sbjct: 1818 ALTLKVTGLGTTREVELPLTNFRSTIFYYVQKLLQLSCNGNVKSDKLRRIWEPTYTIMYR 1877
Query: 849 EKKITGKEKENSRME----ENAENHIGVTEV 875
E K + KEKEN +M E+ E ++G E+
Sbjct: 1878 EMKDSDKEKENGKMGCWSIEHVEQYLGTDEL 1908
>gi|122891874 keratin associated protein 5-5 [Homo sapiens]
Length = 237
Score = 35.4 bits (80), Expect = 0.35
Identities = 31/89 (34%), Positives = 33/89 (37%), Gaps = 8/89 (8%)
Query: 452 CDKACNNSACDWDGGDCSG-NSGGSRYIAGGGGTGSIGVGQPWQFGGGINSVSYCNQGCA 510
C C S C G C G SG +G GG GS G G G G C GC
Sbjct: 6 CSGGCG-SGCGGRGSGCGGCGSGCGGCGSGCGGCGS-GCGGCGGCGSGCAGCGGCGSGCC 63
Query: 511 NSWLADK---FCDQACNVLSCGFDAGDCG 536
K C AC+ SCG G CG
Sbjct: 64 VPVCCCKPMCCCVPACSCSSCG--KGGCG 90
Score = 33.5 bits (75), Expect = 1.3
Identities = 28/97 (28%), Positives = 33/97 (34%), Gaps = 15/97 (15%)
Query: 441 GCPGSWIKDGYCDKACNNS--ACDWDGGD------CSGNSGGSRYIAGG-GGTGSIGVGQ 491
GC + G C +C S C GG C G+ GG G GG GS G Q
Sbjct: 98 GCVSCGVSKGACG-SCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSYGCSQ 156
Query: 492 PWQFGGGINSVSYCNQGCANSWLADKFCDQACNVLSC 528
C+ GC +S C C SC
Sbjct: 157 -----SSCCKPCCCSSGCGSSCCQSSCCKPYCCQSSC 188
>gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]
Length = 1567
Score = 35.0 bits (79), Expect = 0.45
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 703 LPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFL 740
LP + + SL L+L+L GDIT KGY ++ LL ++
Sbjct: 13 LPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYI 50
>gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]
Length = 1571
Score = 35.0 bits (79), Expect = 0.45
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 703 LPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFL 740
LP + + SL L+L+L GDIT KGY ++ LL ++
Sbjct: 13 LPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYI 50
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 35.0 bits (79), Expect = 0.45
Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 6/45 (13%)
Query: 433 WPVPNCAEGC-PGSWIKDGYCDKAC---NNSACDWDGGDCSGNSG 473
W +C+ C PG W CDK C NNS+CD G CS SG
Sbjct: 126 WRGDDCSSECAPGMW--GPQCDKPCSCGNNSSCDPKSGVCSCPSG 168
>gi|116174738 pappalysin 2 isoform 1 [Homo sapiens]
Length = 1791
Score = 35.0 bits (79), Expect = 0.45
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 437 NCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYI 478
+C + C + DG+CD N + C +DGGDC ++ S+ +
Sbjct: 1728 HCIQSCE-PFQADGWCDTINNRAYCHYDGGDCCSSTLSSKKV 1768
>gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]
Length = 798
Score = 35.0 bits (79), Expect = 0.45
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 703 LPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFL 740
LP + + SL L+L+L GDIT KGY ++ LL ++
Sbjct: 13 LPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYI 50
>gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]
Length = 812
Score = 35.0 bits (79), Expect = 0.45
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 703 LPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFL 740
LP + + SL L+L+L GDIT KGY ++ LL ++
Sbjct: 13 LPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYI 50
>gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]
Length = 841
Score = 35.0 bits (79), Expect = 0.45
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 703 LPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFL 740
LP + + SL L+L+L GDIT KGY ++ LL ++
Sbjct: 13 LPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYI 50
>gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]
Length = 889
Score = 35.0 bits (79), Expect = 0.45
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 703 LPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFL 740
LP + + SL L+L+L GDIT KGY ++ LL ++
Sbjct: 13 LPAEVRESLAELELELSEGDITQKGYEKKRAKLLARYI 50
>gi|44888818 DIP2 disco-interacting protein 2 homolog C [Homo
sapiens]
Length = 1556
Score = 35.0 bits (79), Expect = 0.45
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 703 LPKDAQLSLNTLDLQLEHGDITLKGYNLSKSALLRSFL 740
LP + + L L+L+L GDIT KGY +S L+ ++L
Sbjct: 11 LPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYL 48
>gi|30387646 late cornified envelope 1F [Homo sapiens]
Length = 118
Score = 34.3 bits (77), Expect = 0.77
Identities = 15/50 (30%), Positives = 18/50 (36%)
Query: 434 PVPNCAEGCPGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYIAGGGG 483
P P C CP C + C G C + GG +GGGG
Sbjct: 25 PTPKCPPKCPPKCPPVSSCCSVSSGGCCGSSSGGCCSSGGGGCCSSGGGG 74
>gi|123702038 keratin associated protein 5-9 [Homo sapiens]
Length = 169
Score = 34.3 bits (77), Expect = 0.77
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 23/102 (22%)
Query: 437 NCAEGCPG---SWIKDGYCDK-------ACNNSACDWDGGDCSGNSGGSRYIAGGGGTGS 486
+C GC G S YC K AC+ S+C G G+ GGS+ GG GS
Sbjct: 23 SCGSGCRGCGPSCCAPVYCCKPVCCCVPACSCSSCGKRG---CGSCGGSK-----GGCGS 74
Query: 487 IGVGQPWQFGGGINSVSYCNQGCANSWLADKFCDQACNVLSC 528
G Q C+ GC +S C C+ SC
Sbjct: 75 CGCSQC-----SCCKPCCCSSGCGSSCCQCSCCKPYCSQCSC 111
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 33.9 bits (76), Expect = 1.0
Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
Query: 450 GYCDKACNNSACDWDGGD----CSGNSGGSRYIAGGGGTGSIGVGQPWQFGGG 498
GY C + GG C G SGGS +GGGG+ G G GGG
Sbjct: 58 GYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGG 110
Score = 31.2 bits (69), Expect = 6.5
Identities = 17/48 (35%), Positives = 20/48 (41%)
Query: 465 GGDCSGNSGGSRYIAGGGGTGSIGVGQPWQFGGGINSVSYCNQGCANS 512
GG G+SG +GGGG G G GGG + C G S
Sbjct: 40 GGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGS 87
>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
Length = 330
Score = 33.9 bits (76), Expect = 1.0
Identities = 23/70 (32%), Positives = 28/70 (40%), Gaps = 8/70 (11%)
Query: 441 GC--PGSWIKDGYCDKACNNSACDWDGGDCSGNSGGSRYIAGGGGTGSIGVGQPWQFGGG 498
GC P S ++DG C GG + GGS G GG G+ G G P GG
Sbjct: 32 GCMGPASRLQDGEYGLGC------LVGGAYTYGGGGSAAATGAGGAGAYGTGGPGGPGGP 85
Query: 499 INSVSYCNQG 508
C+ G
Sbjct: 86 AGGGGACSMG 95
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 33.5 bits (75), Expect = 1.3
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 443 PGSWIKDGYCDKACNNSACDWDG--GDCSGNSGGSRYIAGGGG-TGSIGVGQPWQFGGGI 499
P +K G + + + +A G GD G SGG + GGGG + + G G GGG
Sbjct: 130 PRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGA 189
Query: 500 NSVSYCNQGCAN 511
NS + C +
Sbjct: 190 NSKPAQKKSCGS 201
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,459,052
Number of Sequences: 37866
Number of extensions: 2298791
Number of successful extensions: 8942
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 8511
Number of HSP's gapped (non-prelim): 363
length of query: 1256
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1142
effective length of database: 13,930,794
effective search space: 15908966748
effective search space used: 15908966748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.