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Search of human proteins with 38198663
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38198663 potassium channel tetramerisation domain containing
8 [Homo sapiens]
(473 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38198663 potassium channel tetramerisation domain containing ... 954 0.0
gi|55926200 potassium channel tetramerisation domain containing ... 495 e-140
gi|19923973 potassium channel tetramerisation domain containing ... 315 7e-86
gi|71143104 potassium channel tetramerisation domain containing ... 88 2e-17
gi|189571693 potassium channel tetramerisation domain containing... 83 6e-16
gi|189571691 potassium channel tetramerisation domain containing... 83 6e-16
gi|146198864 potassium channel tetramerisation domain containing... 80 5e-15
gi|142356950 potassium channel tetramerisation domain containing... 77 3e-14
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens] 76 8e-14
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens] 76 8e-14
gi|23308551 potassium channel tetramerisation domain containing ... 75 1e-13
gi|194018443 potassium channel tetramerisation domain containing... 74 2e-13
gi|194018441 potassium channel tetramerisation domain containing... 74 2e-13
gi|194018439 potassium channel tetramerisation domain containing... 74 2e-13
gi|218505694 potassium channel tetramerisation domain containing... 69 7e-12
gi|209969708 potassium channel tetramerisation domain containing... 69 7e-12
gi|40217617 potassium channel tetramerisation domain containing ... 69 7e-12
gi|13994353 potassium channel tetramerisation domain containing ... 64 3e-10
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens] 62 9e-10
gi|53829365 potassium channel tetramerisation domain containing ... 61 2e-09
gi|45387953 potassium channel tetramerization domain containing ... 60 4e-09
gi|30578412 potassium channel tetramerisation domain containing ... 59 1e-08
gi|46255026 potassium channel tetramerisation domain containing ... 58 2e-08
gi|9506651 potassium channel tetramerisation domain containing 5... 57 3e-08
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo... 54 2e-07
gi|169234778 potassium channel tetramerisation domain containing... 52 9e-07
gi|39753959 potassium channel tetramerisation domain containing ... 50 4e-06
gi|169184031 PREDICTED: similar to potassium channel tetramerisa... 47 4e-05
gi|169179790 PREDICTED: similar to potassium channel tetramerisa... 47 4e-05
gi|169180181 PREDICTED: similar to potassium channel tetramerisa... 47 4e-05
>gi|38198663 potassium channel tetramerisation domain containing 8
[Homo sapiens]
Length = 473
Score = 954 bits (2466), Expect = 0.0
Identities = 473/473 (100%), Positives = 473/473 (100%)
Query: 1 MALKDTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHS 60
MALKDTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHS
Sbjct: 1 MALKDTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHS 60
Query: 61 TLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLAL 120
TLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLAL
Sbjct: 61 TLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLAL 120
Query: 121 PEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLR 180
PEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLR
Sbjct: 121 PEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLR 180
Query: 181 GAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGR 240
GAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGR
Sbjct: 181 GAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGR 240
Query: 241 IALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAA 300
IALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAA
Sbjct: 241 IALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAA 300
Query: 301 FVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSC 360
FVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSC
Sbjct: 301 FVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSC 360
Query: 361 DSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPVQWIPPPDKRRNSELFQTLISKS 420
DSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPVQWIPPPDKRRNSELFQTLISKS
Sbjct: 361 DSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPVQWIPPPDKRRNSELFQTLISKS 420
Query: 421 RETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL 473
RETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL
Sbjct: 421 RETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL 473
>gi|55926200 potassium channel tetramerisation domain containing 16
[Homo sapiens]
Length = 428
Score = 495 bits (1274), Expect = e-140
Identities = 270/441 (61%), Positives = 317/441 (71%), Gaps = 30/441 (6%)
Query: 35 GPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSR 94
G P+ FPEVVELNVGGQVY T+HSTL+S+P S L MFSP +L +DS+
Sbjct: 16 GSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTAN-----DLAKDSK 70
Query: 95 ARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQN 154
RFFIDRDGFLFRY+LDYLRD+Q+ LP+HFPEK RL REAEYFQL DLVKLL+P KQ+
Sbjct: 71 GRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQS 130
Query: 155 SLNDEGCQSDLEDNVSQGSSDALLLRGAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYR 214
DE C SD ED SQGS + ++ +P+ D++ GF+T+GYR
Sbjct: 131 P--DEFCHSDFED-ASQGSDTRIC--PPSSLLPA--------------DRKWGFITVGYR 171
Query: 215 GSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFT 274
GS T R+ QADAKFRRV RI+VCGRI+LAKEVFG+TLNESRDPDR PE+YTSRFYLKF
Sbjct: 172 GSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFK 231
Query: 275 YLEQAFDRLSEAGFHMVACNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHE 334
+LE+AFD LSE GFHMVACNSS TA+F+NQY DDKIWSSYTEY+F+R P + SP
Sbjct: 232 HLERAFDMLSECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSR-WSPSHCDC 290
Query: 335 DRKHDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSK 394
K+ K DK ESGTSCN+LSTSSCDS SEAS+PQ+ Q N TLDRP K
Sbjct: 291 CCKNGK-GDKEGESGTSCNDLSTSSCDSQSEASSPQETVICG--PVTRQTNIQTLDRPIK 347
Query: 395 KAPVQWIPPPDKRRNSELFQTLISKSRETNLSKKK--VCEKLSVEEEMKKCIQDFKKIHI 452
K PVQ I + RR S+L +TL S SRE+N+S KK V EKLS+EEE++KCIQDF KI I
Sbjct: 348 KGPVQLIQQSEMRRKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKI 407
Query: 453 PDYFPERKRQWQSELLQKYGL 473
PD FPERK WQSELL+KY L
Sbjct: 408 PDRFPERKHPWQSELLRKYHL 428
>gi|19923973 potassium channel tetramerisation domain containing 12
[Homo sapiens]
Length = 325
Score = 315 bits (806), Expect = 7e-86
Identities = 172/323 (53%), Positives = 213/323 (65%), Gaps = 43/323 (13%)
Query: 27 GASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRR 86
G + ++ P FP++VELNVGGQVYVT+ T++SVPDS L MF+ P+
Sbjct: 17 GGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQ------ 70
Query: 87 GELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLL 146
EL RDS+ RFF+DRDGFLFRY+LDYLRD QL LP++FPE+ RL REAEYF+L +LV+ L
Sbjct: 71 -ELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129
Query: 147 SPK-------------VTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAVPS----- 188
V K+ SL DE + G S+ GA+A PS
Sbjct: 130 GAPQQPGPGPPPSRRGVHKEGSLGDE--------LLPLGYSEPEQQEGASAGAPSPTLEL 181
Query: 189 GPGAHGGGGGGGAQ--------DKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGR 240
+ GG G +RSG++T+GYRGSYT RD QADAKFRRVARI VCG+
Sbjct: 182 ASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQADAKFRRVARITVCGK 241
Query: 241 IALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAA 300
+LAKEVFGDTLNESRDPDR PE+YTSR+YLKF +LEQAFD+LSE+GFHMVAC+S+GT A
Sbjct: 242 TSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCA 301
Query: 301 FVN--QYRDDKIWSSYTEYIFFR 321
F + +DKIW+SYTEY+F R
Sbjct: 302 FASSTDQSEDKIWTSYTEYVFCR 324
>gi|71143104 potassium channel tetramerisation domain containing 21
[Homo sapiens]
Length = 260
Score = 87.8 bits (216), Expect = 2e-17
Identities = 47/104 (45%), Positives = 63/104 (60%), Gaps = 9/104 (8%)
Query: 46 VELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFL 105
+ LNVGG++Y T +TL S PDS L +MFS P RDS+ FIDRDG +
Sbjct: 5 ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPT---------KRDSQGNCFIDRDGKV 55
Query: 106 FRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPK 149
FRY+L++LR L LPE F E L REA+++Q+ L++ L K
Sbjct: 56 FRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEK 99
>gi|189571693 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 82.8 bits (203), Expect = 6e-16
Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 9/102 (8%)
Query: 46 VELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFL 105
V LNVGG +Y T +TL PDS L +MF P RD + +FIDRDG L
Sbjct: 14 VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTA---------RDPQGNYFIDRDGPL 64
Query: 106 FRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLS 147
FRYVL++LR +L LP F E + L +EA+++Q+ L++ L+
Sbjct: 65 FRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLN 106
>gi|189571691 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 82.8 bits (203), Expect = 6e-16
Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 9/102 (8%)
Query: 46 VELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFL 105
V LNVGG +Y T +TL PDS L +MF P RD + +FIDRDG L
Sbjct: 14 VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTA---------RDPQGNYFIDRDGPL 64
Query: 106 FRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLS 147
FRYVL++LR +L LP F E + L +EA+++Q+ L++ L+
Sbjct: 65 FRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLN 106
>gi|146198864 potassium channel tetramerisation domain containing 4
[Homo sapiens]
Length = 259
Score = 79.7 bits (195), Expect = 5e-15
Identities = 46/126 (36%), Positives = 72/126 (57%), Gaps = 13/126 (10%)
Query: 45 VVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGEL--PRDSRARFFIDRD 102
++ LNVGG +Y+T+ TL PD+ L + + G++ P D+ +FIDRD
Sbjct: 34 LMTLNVGGYLYITQKQTLTKYPDTFLEGIVN-----------GKILCPFDADGHYFIDRD 82
Query: 103 GFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQ 162
G LFR+VL++LR+ +L LPE F E + L +EAE+FQL L + + + K+ E
Sbjct: 83 GLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTF 142
Query: 163 SDLEDN 168
++ DN
Sbjct: 143 LEITDN 148
>gi|142356950 potassium channel tetramerisation domain containing 14
[Homo sapiens]
Length = 255
Score = 77.4 bits (189), Expect = 3e-14
Identities = 62/180 (34%), Positives = 88/180 (48%), Gaps = 27/180 (15%)
Query: 15 PISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMF 74
P+ M S + P +P P P+ VVELNVGG+ + T TL P S LA MF
Sbjct: 10 PVGRMTSQTPLP-----QSPRPRRPT-MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMF 63
Query: 75 SPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREA 134
S + + D+ RFFIDR FR +LDYLR Q+ +H PE + REA
Sbjct: 64 SSLA---------KASTDAEGRFFIDRPSTYFRPILDYLRTGQVP-TQHIPE---VYREA 110
Query: 135 EYFQLTDLVKLLS--PKV------TKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAV 186
+++++ LVKLL P++ KQ L G +LE V ++A+ R ++ V
Sbjct: 111 QFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLV 170
>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
Length = 229
Score = 75.9 bits (185), Expect = 8e-14
Identities = 43/105 (40%), Positives = 61/105 (58%), Gaps = 9/105 (8%)
Query: 44 EVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDG 103
E+V LNVGG+++ T+ ST+ P S LA M R + + + F+DRDG
Sbjct: 5 ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDG---------RDQEFKMVGGQIFVDRDG 55
Query: 104 FLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSP 148
LF ++LD+LR QL LP F + RL REA +++L LV LL+P
Sbjct: 56 DLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNP 100
>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
Length = 272
Score = 75.9 bits (185), Expect = 8e-14
Identities = 43/105 (40%), Positives = 61/105 (58%), Gaps = 9/105 (8%)
Query: 44 EVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDG 103
E+V LNVGG+++ T+ ST+ P S LA M R + + + F+DRDG
Sbjct: 5 ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDG---------RDQEFKMVGGQIFVDRDG 55
Query: 104 FLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSP 148
LF ++LD+LR QL LP F + RL REA +++L LV LL+P
Sbjct: 56 DLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNP 100
>gi|23308551 potassium channel tetramerisation domain containing 7
[Homo sapiens]
Length = 289
Score = 75.1 bits (183), Expect = 1e-13
Identities = 49/126 (38%), Positives = 69/126 (54%), Gaps = 18/126 (14%)
Query: 24 SSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGA 83
++P A+ A P P FPEVV LN+GG + T+ STL D+ LA+MFS
Sbjct: 31 ATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFS-------- 82
Query: 84 RRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKER---LLREAEYFQLT 140
R +P DS R+FIDRDG F VL++LR L P +ER + +EA+Y+ +
Sbjct: 83 -GRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDL------PPRERVRAVYKEAQYYAIG 135
Query: 141 DLVKLL 146
L++ L
Sbjct: 136 PLLEQL 141
>gi|194018443 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 74.3 bits (181), Expect = 2e-13
Identities = 56/188 (29%), Positives = 88/188 (46%), Gaps = 12/188 (6%)
Query: 2 ALKDTGSGGSTILPISEMVSSSSSPGASAAAA--PGPCAPSPFPEVVELNVGGQVYVTKH 59
+L GS G+ +S + SP + AA P P + V ++VGG +Y +
Sbjct: 12 SLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSL 71
Query: 60 STLLSVPDSTLASMFSPSSPRGGARRRGELPRDS-RARFFIDRDGFLFRYVLDYLRDKQL 118
+TL PDS ++ +F+ + P + DS + +FIDRDG +FRYVL +LR +L
Sbjct: 72 ATLTKYPDSRISRLFNGTEP---------IVLDSLKQHYFIDRDGEIFRYVLSFLRTSKL 122
Query: 119 ALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALL 178
LP+ F + L EA Y+QL +V+ L +Q L V+ + +
Sbjct: 123 LLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIA 182
Query: 179 LRGAAAAV 186
L G A +
Sbjct: 183 LSGEKALI 190
>gi|194018441 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 74.3 bits (181), Expect = 2e-13
Identities = 56/188 (29%), Positives = 88/188 (46%), Gaps = 12/188 (6%)
Query: 2 ALKDTGSGGSTILPISEMVSSSSSPGASAAAA--PGPCAPSPFPEVVELNVGGQVYVTKH 59
+L GS G+ +S + SP + AA P P + V ++VGG +Y +
Sbjct: 12 SLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSL 71
Query: 60 STLLSVPDSTLASMFSPSSPRGGARRRGELPRDS-RARFFIDRDGFLFRYVLDYLRDKQL 118
+TL PDS ++ +F+ + P + DS + +FIDRDG +FRYVL +LR +L
Sbjct: 72 ATLTKYPDSRISRLFNGTEP---------IVLDSLKQHYFIDRDGEIFRYVLSFLRTSKL 122
Query: 119 ALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALL 178
LP+ F + L EA Y+QL +V+ L +Q L V+ + +
Sbjct: 123 LLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIA 182
Query: 179 LRGAAAAV 186
L G A +
Sbjct: 183 LSGEKALI 190
>gi|194018439 potassium channel tetramerisation domain containing 15
isoform 1 [Homo sapiens]
Length = 234
Score = 74.3 bits (181), Expect = 2e-13
Identities = 56/188 (29%), Positives = 88/188 (46%), Gaps = 12/188 (6%)
Query: 2 ALKDTGSGGSTILPISEMVSSSSSPGASAAAA--PGPCAPSPFPEVVELNVGGQVYVTKH 59
+L GS G+ +S + SP + AA P P + V ++VGG +Y +
Sbjct: 12 SLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSL 71
Query: 60 STLLSVPDSTLASMFSPSSPRGGARRRGELPRDS-RARFFIDRDGFLFRYVLDYLRDKQL 118
+TL PDS ++ +F+ + P + DS + +FIDRDG +FRYVL +LR +L
Sbjct: 72 ATLTKYPDSRISRLFNGTEP---------IVLDSLKQHYFIDRDGEIFRYVLSFLRTSKL 122
Query: 119 ALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALL 178
LP+ F + L EA Y+QL +V+ L +Q L V+ + +
Sbjct: 123 LLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIA 182
Query: 179 LRGAAAAV 186
L G A +
Sbjct: 183 LSGEKALI 190
>gi|218505694 potassium channel tetramerisation domain containing 1
isoform b [Homo sapiens]
Length = 865
Score = 69.3 bits (168), Expect = 7e-12
Identities = 38/126 (30%), Positives = 67/126 (53%), Gaps = 10/126 (7%)
Query: 19 MVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSS 78
+++ S + + P P + V ++VGG +Y + +TL P+S + +F +
Sbjct: 613 LITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTE 672
Query: 79 PRGGARRRGELPRDS-RARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYF 137
P + DS + +FIDRDG +FRY+L++LR +L +P+ F + L EA+YF
Sbjct: 673 P---------IVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYF 723
Query: 138 QLTDLV 143
QL ++
Sbjct: 724 QLQPML 729
>gi|209969708 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 69.3 bits (168), Expect = 7e-12
Identities = 38/126 (30%), Positives = 67/126 (53%), Gaps = 10/126 (7%)
Query: 19 MVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSS 78
+++ S + + P P + V ++VGG +Y + +TL P+S + +F +
Sbjct: 5 LITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTE 64
Query: 79 PRGGARRRGELPRDS-RARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYF 137
P + DS + +FIDRDG +FRY+L++LR +L +P+ F + L EA+YF
Sbjct: 65 P---------IVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYF 115
Query: 138 QLTDLV 143
QL ++
Sbjct: 116 QLQPML 121
>gi|40217617 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 69.3 bits (168), Expect = 7e-12
Identities = 38/126 (30%), Positives = 67/126 (53%), Gaps = 10/126 (7%)
Query: 19 MVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSS 78
+++ S + + P P + V ++VGG +Y + +TL P+S + +F +
Sbjct: 5 LITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTE 64
Query: 79 PRGGARRRGELPRDS-RARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYF 137
P + DS + +FIDRDG +FRY+L++LR +L +P+ F + L EA+YF
Sbjct: 65 P---------IVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYF 115
Query: 138 QLTDLV 143
QL ++
Sbjct: 116 QLQPML 121
>gi|13994353 potassium channel tetramerisation domain containing 10
[Homo sapiens]
Length = 313
Score = 63.9 bits (154), Expect = 3e-10
Identities = 50/127 (39%), Positives = 65/127 (51%), Gaps = 11/127 (8%)
Query: 18 EMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPS 77
E V SS+ P A+A SP + V+LNVGG +Y T TL D+ L +MFS
Sbjct: 7 ESVVSSAVP-AAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSG- 63
Query: 78 SPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYF 137
R E+ DS IDR G F +L+YLRD + LPE E E LL EA+Y+
Sbjct: 64 --------RMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYY 115
Query: 138 QLTDLVK 144
+ LV+
Sbjct: 116 LVQGLVE 122
>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
Length = 707
Score = 62.4 bits (150), Expect = 9e-10
Identities = 43/119 (36%), Positives = 61/119 (51%), Gaps = 11/119 (9%)
Query: 28 ASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRG 87
A+A AA G + P EV+ LNVGG+ + T TL +PDS +S+ S R
Sbjct: 3 AAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLS---------GRI 53
Query: 88 ELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLL 146
+D FIDRD +F +L++LR K+ L LL EA+++ LT LV+ L
Sbjct: 54 STLKDETGAIFIDRDPTVFAPILNFLRTKE--LDPRGVHGSSLLHEAQFYGLTPLVRRL 110
>gi|53829365 potassium channel tetramerisation domain containing 2
[Homo sapiens]
Length = 263
Score = 61.2 bits (147), Expect = 2e-09
Identities = 50/174 (28%), Positives = 71/174 (40%), Gaps = 27/174 (15%)
Query: 7 GSGGSTILPISEMVSSSSSP----------GASAAAAPGPCAPSPFPEV----------V 46
G GGS + V SP G AAA P P P P V
Sbjct: 15 GGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPGPPERAGGGGAARWV 74
Query: 47 ELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLF 106
LNVGG +VT TL P S L + P + +D + IDRD F
Sbjct: 75 RLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDS------DKDETGAYLIDRDPTYF 128
Query: 107 RYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEG 160
+L+YLR +L + + E E +L EAE++ + LV+L+ ++ + +G
Sbjct: 129 GPILNYLRHGKLIITKELAE-EGVLEEAEFYNIASLVRLVKERIRDNENRTSQG 181
>gi|45387953 potassium channel tetramerization domain containing 18
[Homo sapiens]
Length = 426
Score = 60.1 bits (144), Expect = 4e-09
Identities = 37/94 (39%), Positives = 49/94 (52%), Gaps = 10/94 (10%)
Query: 44 EVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDG 103
+V+ LNVGG +Y + +L DS LASMFS P L D IDRDG
Sbjct: 12 DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFP---------LKTDESGACVIDRDG 62
Query: 104 FLFRYVLDYLRDKQLALPEHFPEKERLLREAEYF 137
LF+Y+LDYL ++ +P + L EA+YF
Sbjct: 63 RLFKYLLDYLHG-EVQIPTDEQTRIALQEEADYF 95
>gi|30578412 potassium channel tetramerisation domain containing 13
[Homo sapiens]
Length = 329
Score = 58.5 bits (140), Expect = 1e-08
Identities = 48/141 (34%), Positives = 68/141 (48%), Gaps = 25/141 (17%)
Query: 19 MVSSSSSPGASAAAA----------PGPCAP-----SPFPEVVELNVGGQVYVTKHSTLL 63
M + +S P A+AA + PGP A +P + V+LNVGG ++ T TL
Sbjct: 1 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT 60
Query: 64 SVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEH 123
D+ L +MFS R E+ D+ IDR G F +L+YLRD + LPE
Sbjct: 61 G-QDTMLKAMFSG---------RVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPES 110
Query: 124 FPEKERLLREAEYFQLTDLVK 144
E LL EA Y+ + L++
Sbjct: 111 TRELGELLGEARYYLVQGLIE 131
>gi|46255026 potassium channel tetramerisation domain containing 3
[Homo sapiens]
Length = 815
Score = 57.8 bits (138), Expect = 2e-08
Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 11/111 (9%)
Query: 36 PCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRA 95
P A + E+V+LNVGG + T TL+ +PDS +S+ S R RD
Sbjct: 10 PAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLS---------GRISTLRDETG 60
Query: 96 RFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLL 146
FIDRD F +L++LR K+L L L EAE++ +T LV+ L
Sbjct: 61 AIFIDRDPAAFAPILNFLRTKELDL--RGVSINVLRHEAEFYGITPLVRRL 109
>gi|9506651 potassium channel tetramerisation domain containing 5
[Homo sapiens]
Length = 234
Score = 57.4 bits (137), Expect = 3e-08
Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 39 PSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFF 98
P + V LNVGG ++T TL P S L + + +D +
Sbjct: 39 PGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDL-------DSDKDETGAYL 91
Query: 99 IDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNS 155
IDRD F VL+YLR +L + + E E +L EAE++ +T L+KL+ K+ +++S
Sbjct: 92 IDRDPTYFGPVLNYLRHGKLVINKDLAE-EGVLEEAEFYNITSLIKLVKDKIRERDS 147
>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
sapiens]
Length = 316
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/122 (33%), Positives = 58/122 (47%), Gaps = 25/122 (20%)
Query: 46 VELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFL 105
V+LNVGG +Y T L D+ L +MFS R E+ D IDR G
Sbjct: 30 VQLNVGGSLYYTTVRALTR-HDTMLKAMFSG---------RMEVLTDKEGWILIDRCGKH 79
Query: 106 FRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDL 165
F +L+YLRD + LP++ E + L+ EA+Y+ + LV + CQS L
Sbjct: 80 FGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNM---------------CQSAL 124
Query: 166 ED 167
+D
Sbjct: 125 QD 126
>gi|169234778 potassium channel tetramerisation domain containing 17
[Homo sapiens]
Length = 297
Score = 52.4 bits (124), Expect = 9e-07
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 13/140 (9%)
Query: 15 PISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMF 74
P M + ++P A A G A + + V LNVGG V++T TL S L+ +
Sbjct: 6 PAMRMEAGEAAPPAGA----GGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLC 61
Query: 75 SPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREA 134
+ RD + IDRD F +L++LR +L L + E E +L EA
Sbjct: 62 QGEELQSD--------RDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAE-EGVLEEA 112
Query: 135 EYFQLTDLVKLLSPKVTKQN 154
E++ + L++++ ++ +++
Sbjct: 113 EFYNIGPLIRIIKDRMEEKD 132
>gi|39753959 potassium channel tetramerisation domain containing 9
[Homo sapiens]
Length = 389
Score = 50.1 bits (118), Expect = 4e-06
Identities = 37/112 (33%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 48 LNVGGQVYVTKHSTLLSV-PDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLF 106
LNVGG+ + T STL++ PDS LA MF G + D R F IDR F
Sbjct: 93 LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQ-------DHRGAFLIDRSPEYF 145
Query: 107 RYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLND 158
+L+YLR QL + + +L EA +F + L++ L + D
Sbjct: 146 EPILNYLRHGQLIVNDGI-NLLGVLEEARFFGIDSLIEHLEVAIKNSQPPED 196
>gi|169184031 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 47.0 bits (110), Expect = 4e-05
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 11/109 (10%)
Query: 48 LNVGGQVYVTKHSTLLSV-PDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLF 106
L+VGGQ + T STL++ PD LA MF G + D R F ID+ F
Sbjct: 93 LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQ-------DHRGAFLIDQSPEYF 145
Query: 107 RYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNS 155
+L+YLR QL + + + +L EA +F + L++ L KV +NS
Sbjct: 146 EPILNYLRHGQLIVNDGI-DLLGVLEEARFFGIDSLIEHL--KVAIKNS 191
>gi|169179790 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 47.0 bits (110), Expect = 4e-05
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 11/109 (10%)
Query: 48 LNVGGQVYVTKHSTLLSV-PDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLF 106
L+VGGQ + T STL++ PD LA MF G + D R F ID+ F
Sbjct: 93 LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQ-------DHRGAFLIDQSPEYF 145
Query: 107 RYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNS 155
+L+YLR QL + + + +L EA +F + L++ L KV +NS
Sbjct: 146 EPILNYLRHGQLIVNDGI-DLLGVLEEARFFGIDSLIEHL--KVAIKNS 191
>gi|169180181 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 47.0 bits (110), Expect = 4e-05
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 11/109 (10%)
Query: 48 LNVGGQVYVTKHSTLLSV-PDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLF 106
L+VGGQ + T STL++ PD LA MF G + D R F ID+ F
Sbjct: 93 LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQ-------DHRGAFLIDQSPEYF 145
Query: 107 RYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNS 155
+L+YLR QL + + + +L EA +F + L++ L KV +NS
Sbjct: 146 EPILNYLRHGQLIVNDGI-DLLGVLEEARFFGIDSLIEHL--KVAIKNS 191
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,385,672
Number of Sequences: 37866
Number of extensions: 1018228
Number of successful extensions: 8109
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 7372
Number of HSP's gapped (non-prelim): 647
length of query: 473
length of database: 18,247,518
effective HSP length: 106
effective length of query: 367
effective length of database: 14,233,722
effective search space: 5223775974
effective search space used: 5223775974
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.