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Search of human proteins with 38158015
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38158015 mastermind-like 3 [Homo sapiens]
(1133 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38158015 mastermind-like 3 [Homo sapiens] 2286 0.0
gi|7661990 mastermind-like 1 [Homo sapiens] 514 e-145
gi|33286444 mastermind-like 2 [Homo sapiens] 308 1e-83
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 102 3e-21
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 96 2e-19
gi|56549696 E1A binding protein p400 [Homo sapiens] 89 3e-17
gi|119943102 CREB binding protein isoform b [Homo sapiens] 82 2e-15
gi|119943104 CREB binding protein isoform a [Homo sapiens] 82 2e-15
gi|221139761 zinc finger protein 853 [Homo sapiens] 77 7e-14
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 77 9e-14
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 77 9e-14
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 77 9e-14
gi|50345997 E1A binding protein p300 [Homo sapiens] 75 5e-13
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 73 2e-12
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 72 2e-12
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 72 2e-12
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 72 2e-12
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 72 2e-12
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 72 2e-12
gi|55750053 atrophin-1 [Homo sapiens] 71 5e-12
gi|55750041 atrophin-1 [Homo sapiens] 71 5e-12
gi|4507379 TATA box binding protein [Homo sapiens] 69 2e-11
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 69 3e-11
gi|93141033 PAX interacting protein 1 [Homo sapiens] 67 7e-11
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 67 1e-10
gi|55956910 meningioma 1 [Homo sapiens] 67 1e-10
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 66 2e-10
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 66 2e-10
gi|162951884 R3H domain containing 2 [Homo sapiens] 66 2e-10
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 65 4e-10
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 2286 bits (5924), Expect = 0.0
Identities = 1133/1133 (100%), Positives = 1133/1133 (100%)
Query: 1 MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGP 60
MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGP
Sbjct: 1 MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGP 60
Query: 61 GGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQ 120
GGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQ
Sbjct: 61 GGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQ 120
Query: 121 RAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA 180
RAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA
Sbjct: 121 RAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA 180
Query: 181 CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLL 240
CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLL
Sbjct: 181 CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLL 240
Query: 241 EDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFS 300
EDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFS
Sbjct: 241 EDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFS 300
Query: 301 DINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD 360
DINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD
Sbjct: 301 DINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD 360
Query: 361 PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQT 420
PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQT
Sbjct: 361 PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQT 420
Query: 421 PNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAK 480
PNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAK
Sbjct: 421 PNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAK 480
Query: 481 LMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYP 540
LMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYP
Sbjct: 481 LMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYP 540
Query: 541 QAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKP 600
QAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKP
Sbjct: 541 QAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKP 600
Query: 601 LTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLS 660
LTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLS
Sbjct: 601 LTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLS 660
Query: 661 EDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASP 720
EDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASP
Sbjct: 661 EDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASP 720
Query: 721 AGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLP 780
AGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLP
Sbjct: 721 AGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLP 780
Query: 781 RQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPG 840
RQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPG
Sbjct: 781 RQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPG 840
Query: 841 TMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPAS 900
TMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPAS
Sbjct: 841 TMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPAS 900
Query: 901 GQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQ 960
GQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQ
Sbjct: 901 GQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQ 960
Query: 961 RSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAA 1020
RSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAA
Sbjct: 961 RSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAA 1020
Query: 1021 MGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYE 1080
MGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYE
Sbjct: 1021 MGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYE 1080
Query: 1081 RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP 1133
RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
Sbjct: 1081 RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP 1133
>gi|7661990 mastermind-like 1 [Homo sapiens]
Length = 1016
Score = 514 bits (1323), Expect = e-145
Identities = 384/1110 (34%), Positives = 560/1110 (50%), Gaps = 149/1110 (13%)
Query: 66 AVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKS 125
A+P+HS V+ERLR+RIE CRRHH CE RY+ E+LELER+ T +L+QR ++ +AK++
Sbjct: 12 ALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRA 71
Query: 126 GAG----TGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGAC 181
G P+ P +AA + L +TVKR L+ A SP NGDQQNG
Sbjct: 72 GKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATSPQNGDQQNGY- 130
Query: 182 DGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLP--LQNSGTHTPGL 239
G+ P K+ R++ G+ +N LP ASPL Q D KPS LQ+SG H+ GL
Sbjct: 131 -GDLFPGHKKTRREAPLGVAISSN-----GLPPASPLGQSD-KPSGADALQSSGKHSLGL 183
Query: 240 LEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLF 299
+ L+K RL + L +NG S+ +SF + +K+LKQEP++D C+ T +Q+ L
Sbjct: 184 -DSLNKK-RLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNLM 241
Query: 300 SDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKS 359
D+NLN+QEW+ELI+EL +VP++D++DLFNEDFEEKK+PE S AT+TPL+Q+ ++K+
Sbjct: 242 PDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQD-INIKT 300
Query: 360 DPSHSPFAHVSMGSPQARPSSSGPPF---STVSTATSLPSVAST---------PAAPNPA 407
+ S + F +GSPQ R S+G F S+ +T PS+ + P A NP+
Sbjct: 301 EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS 360
Query: 408 SS--PANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPA 465
+ PA+ Q+ Q G P G G +S++S A
Sbjct: 361 PNLMPASAQAQNAQRA----LAGVVLPSQGPG--------------------GASELSSA 396
Query: 466 EQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYG 525
QL+Q+AA +Q+++Q Q QQ Q S W GP S
Sbjct: 397 HQLQQIAA---------------KQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLD 441
Query: 526 AAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQ-PNNLGTN 584
+ EKP SP Y Q F N ++ P N YL +H+N+++ Q P+NL N
Sbjct: 442 VPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQN 501
Query: 585 SLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQ 644
S N Q ++L YGNTKPL+H+ AD Q P + +K LM Y+ QQ
Sbjct: 502 SANNQGSVLDYGNTKPLSHYKADCGQ--GSPGSGQSKPALMAYLPQQ------------- 546
Query: 645 QQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQ 704
+H+S +Q L LMK K M + +L GQEQ+P +P
Sbjct: 547 -----------LSHISHEQNSLFLMKPK---PGNMPFRSLVPPGQEQNPSSVPVQAQATS 592
Query: 705 SSVPPGSGGMVSGASPAGPGFLGSQPQAAIMK--QMLIDQRAQLIEQQKQQFLREQRQQQ 762
P + + S S +L SQ QAA+MK Q+L+DQ+ Q +QQK +Q+Q
Sbjct: 593 VGTQPPAVSVAS--SHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKH---LQQQQFL 647
Query: 763 QQQQQILAEQQLQ--QSHL---PRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQS 817
Q+QQ +LAEQ+ Q Q HL P Q+ P + +P QQV QF GS AAV L
Sbjct: 648 QRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFP-QQVGQFTGSS---AAVPGMNTLGP 703
Query: 818 MRTS--RLMAQNAGMMGIGPSQ-NPGTMATAAAQSEMGLAPY-STTPTSQPGMYNMSTGM 873
+S R+ Q +M +GP + ++ T + Q + G+A + + Q +Y M++G+
Sbjct: 704 SNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGI 763
Query: 874 TQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQ 933
TQ++ P T+ A PRQ GQ + + +GQ+ L +S ++QQH KG +
Sbjct: 764 TQIVAQPPPQA---TNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQH--NKGTLNP 818
Query: 934 ALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSG--ELGPFNNGASYPLQAGQPR 991
L +P PR+ MG SWQ + + + G+T G + PF +S+ +Q Q
Sbjct: 819 GLTKPPV-PRVSPAMGGQN---SSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQ--QQA 872
Query: 992 LTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARP--------MVM 1043
K PQ SQ+V + + ++ AA ++P + QQ TS P +
Sbjct: 873 HLKMSSPQ-FSQAVPNR---PMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGL 928
Query: 1044 SGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYE-RNAPQDVSYNYSGDGAGGSFPG 1102
GLS P + AFSQ PA Q G A +QAY R A Q++ + YSG G
Sbjct: 929 PGLSPAGPELGAFSQSPASQM---GGRAGLHCTQAYPVRTAGQELPFAYSGQPGGSGLSS 985
Query: 1103 LPDGADLVDSIIKGGPGDEWMQELDELFGN 1132
+ DL+DS++K +EWM +LD+L G+
Sbjct: 986 VAGHTDLIDSLLKNRTSEEWMSDLDDLLGS 1015
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 308 bits (790), Expect = 1e-83
Identities = 347/1276 (27%), Positives = 528/1276 (41%), Gaps = 311/1276 (24%)
Query: 42 AAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVE 101
A P + GG G+G GGGS HS +VERLR RI CR+HH++CE RY++ + E
Sbjct: 5 APPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYERGRAE 64
Query: 102 QLELERRDTVSLYQRTLE-QRAKKSG----------AGTGKQQHPSKPQQDAEAAS---- 146
+ ER T+ L Q A+K+G T P+ P ++AA+
Sbjct: 65 SSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAATAAP 124
Query: 147 -------------------------------------AEQRNHTLIMLQETVKRKLEGAR 169
+QRN LI LQ ++KRK
Sbjct: 125 PPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQVVNL 184
Query: 170 SPLNGDQQNGACDGNFSPTSK-RIRKDISAGMEA--INNLPSNMPLPSASPLHQLDLKPS 226
SP N + NG D +F + R+ +++SAG INN S + + P+ Q L+ +
Sbjct: 185 SPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQI-MSGTLPMSQAPLRKT 243
Query: 227 LPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCID 286
L S TH+PG NG + + K++K+EP + +C
Sbjct: 244 NTLP-SHTHSPG------------------NGLFN-------MGLKEVKKEPGETLSCSK 277
Query: 287 TSETSLSNQN---KLFSD---INLNDQEWQELIDELAN--TVPEDDIQ------------ 326
+ ++ +N + D L D E QEL +EL N P D++
Sbjct: 278 HMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIKQD 337
Query: 327 DLFNEDFEEKKEPEFSQPATETPLSQESASVKSDPSHSP-FAHVSMGSPQARPSSSGPPF 385
D FN D ++ + +P+ L E +KS+ +SP GSPQ RP S+GP F
Sbjct: 338 DPFNIDLGQQSQRSTPRPS----LPMEKIVIKSE--YSPGLTQGPSGSPQLRPPSAGPAF 391
Query: 386 STVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAV 445
S ++A S SSP QS QA P+ G+G
Sbjct: 392 SMANSALS-------------TSSPIPSVPQS-----------QAQPQTGSG-------- 419
Query: 446 TVAGSASGPVAVPS-SDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ 504
A+PS ++S A+QLKQ+AA +QQ A++ QQ Q
Sbjct: 420 -------ASRALPSWQEVSHAQQLKQIAANRQQHARM-------------------QQHQ 453
Query: 505 QQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNL-QKTTMN 563
QQH Q +NWS L + P F EK SP Q F+ Q+ +P +A Q M
Sbjct: 454 QQH--QPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMA 511
Query: 564 NYLPQ-------NHMNMINQQ-PNNLGTNSLNKQHNIL--TYGNTKPLTHFNADLSQRMT 613
NY+ + H++++ QQ P +L + +N H + GNTKPL HFN+D + +
Sbjct: 512 NYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQM 571
Query: 614 PPV-ANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPP------------------------ 648
P V + NK L+ Y QQQQQQQQQQQQQQQQQQ
Sbjct: 572 PSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQ 631
Query: 649 -----PPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAA--LPSHGQEQHPVGLPRTTG 701
Q Q + + Q++ +Q+ QP + A LPS + P+ L +
Sbjct: 632 QQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLL 691
Query: 702 PMQSSVPPGSG-----------------GMVSGASPA---------GPGFLGSQPQAAIM 735
Q P +G G +G SP+ G G++ SQ
Sbjct: 692 LQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ------ 745
Query: 736 KQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAE------QQLQQSHL---PRQHLQP 786
Q L++Q+ +Q Q+ + EQ+QQ QQQ+LA+ Q HL P +
Sbjct: 746 -QSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQ 804
Query: 787 QRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAA 846
+RN +Q Q+ G I+ +QA + T ++ N+ ++ S + GT +
Sbjct: 805 RRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLL----STSHGTRMPSL 860
Query: 847 AQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASG-QGVG 905
+ + + Y P +QP Y++++GM Q+ Q N + N PR P G
Sbjct: 861 STAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNN 920
Query: 906 MVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQR---S 962
V+ FG + NS Q P + + P R ++M T A +W + S
Sbjct: 921 NVATFGAGSVGNS--QQLRPNLTHSMAS-----MPPQRTSNVMITSNTTAPNWASQEGTS 973
Query: 963 LQGMPGRTSGELGPFNNGASY-PLQAGQPRLTKQHFPQ-------------------GLS 1002
Q ++G P A+Y P Q+ Q + Q F Q +S
Sbjct: 974 KQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMS 1033
Query: 1003 QSVVDANTGTVRTLN--PAAMGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPP 1060
Q++ G +R LN P + Q++P+L Q GT GL+Q G+ +QPP
Sbjct: 1034 QTLNGQTMGPLRGLNLRPNQLSTQILPNL-NQSGT---------GLNQSRTGI---NQPP 1080
Query: 1061 AQQQIPSGSFAPSSQSQAYE-RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPG 1119
+ PS +P+ S+A++ + D+++++ P L AD +DS++K PG
Sbjct: 1081 S--LTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPG 1138
Query: 1120 -DEWMQE--LDELFGN 1132
D+WM++ LDE+ GN
Sbjct: 1139 NDDWMKDINLDEILGN 1154
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 102 bits (253), Expect = 3e-21
Identities = 195/817 (23%), Positives = 284/817 (34%), Gaps = 116/817 (14%)
Query: 334 EEKKEPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSS-----GPPFSTV 388
E + + + Q + Q SA + PS SP + Q P GPP
Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPG-QLLPGHGLQPPQGPPGGQA 3652
Query: 389 STATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVA 448
P + P P N A+ Q Q H+ G G L P+
Sbjct: 3653 GGLRLTPGGMALPG--QPGGPFLNTALAQQQ--QQQHSGGA-------GSLAGPSGGFFP 3701
Query: 449 GSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQ-- 506
G+ + P S + QL+ + Q KL QQ+QQQQQQQ Q QQQQQQ
Sbjct: 3702 GNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGP 3761
Query: 507 --HSNQTSNWSPLG--PPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTM 562
+NQ P G PPSS G P P Q + P LQ+
Sbjct: 3762 GVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQ------GPQGMLGPAQVAVLQQQHP 3815
Query: 563 NNYLPQN-HMNMINQQPNNLGTNSLNKQ------HNILT------------YGNTKPLTH 603
PQ H ++ Q L + L +Q H ++T G+ L+H
Sbjct: 3816 GALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSH 3875
Query: 604 FNADLSQRMTPPVANPNKNPLMPYIQQQQQ-------QQQQQQQQQQQQQPPPPQL--QA 654
L P + + +QQQQQ QQQQQQQ QQQQQ QL Q
Sbjct: 3876 LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQ 3935
Query: 655 PRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGM 714
+ L + Q++ L +Q+ + Q Q+Q +GL + + S +
Sbjct: 3936 QQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV 3995
Query: 715 VSG-ASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQ 773
G PA P S P A +L + ++ E Q +
Sbjct: 3996 ALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTP 4055
Query: 774 LQQSHLPRQHLQPQRN---------PYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLM 824
+ P + ++P + P P Q + Q P + Q + + T+
Sbjct: 4056 ESMATEPGE-VKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG-- 4112
Query: 825 AQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSG 884
+ G +G G S ++ AQ + L QPG MTQ L P Q
Sbjct: 4113 GGSHGQLGSGSSSEASSVPHLLAQPSVSLG-------DQPG------SMTQNLLGPQQPM 4159
Query: 885 MSITHNQAQGPRQPASG---------QGVGMVSGFGQSMLVNSAITQQHPQMK--GPVG- 932
+ GP+ P G GVG++ GQ + ++PQ++ P
Sbjct: 4160 LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219
Query: 933 ---QALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGASYPLQ--- 986
QAL + + Q++ T Q LQG+ G +LG F + PLQ
Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLG-CQPQLGGFPGPQTGPLQELG 4278
Query: 987 -----AGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPM 1041
G PRL P LS V G V P + ++ P P Q + ++
Sbjct: 4279 AGPRPQGPPRLPAP--PGALSTGPV---LGPVHPTPPPSSPQE--PKRPSQLPSPSSQLP 4331
Query: 1042 VMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQA 1078
+ L PG P P + P G +P++ A
Sbjct: 4332 TEAQLPPTHPGTPKPQGPTLEP--PPGRVSPAAAQLA 4366
Score = 82.0 bits (201), Expect = 3e-15
Identities = 145/519 (27%), Positives = 198/519 (38%), Gaps = 85/519 (16%)
Query: 624 LMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAA 683
LM + +QQQQQQQQQQQQQQ + LS Q LL K G +
Sbjct: 3591 LMAEYRNKQQQQQQQQQQQQQQH-------SAVLALSPSQSPRLLTKLPGQL-------- 3635
Query: 684 LPSHGQE--QHPVG-----LPRTTGPMQSSVPPG----------------SGGMVSGASP 720
LP HG + Q P G L T G M PG SGG S A P
Sbjct: 3636 LPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGP 3695
Query: 721 AGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLP 780
+G F G+ ++ + Q QL QQ++ L ++ QQQQQQQQ QQ HL
Sbjct: 3696 SGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQ-------QQQHLL 3748
Query: 781 RQ-HLQPQRNPYPVQQVNQFQG-SPQDIAAVRSQAALQSMRTSRLMAQN-AGMMGIGPSQ 837
Q +Q Q+ P Q NQ G PQ + S L + S Q GM+G
Sbjct: 3749 GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLG----- 3803
Query: 838 NPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQ 897
P +A Q L P P Q M + L Q M AQ +Q
Sbjct: 3804 -PAQVAVLQQQHPGALGPQG--PHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQ 3860
Query: 898 PASGQGVGMVSGFG---QSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQG 954
Q G ++G QS++ +S + Q G + Q L + Q + Q L QQ
Sbjct: 3861 QQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSL-QQLQQQQQLQQQQQLQQQQQQQ 3919
Query: 955 AQSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQPRL------TKQHFPQGLSQSVVDA 1008
Q QQ+ LQ + + LQ Q +L +Q F Q Q +
Sbjct: 3920 LQ--QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGL 3977
Query: 1009 NTGTVRTLNPAAMGRQM------MPSLPGQQGTSQAR---PMVMSGLSQGVPGMPAFS-- 1057
+ L+P +Q MP+ P Q +S ++++G Q PA S
Sbjct: 3978 LNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVD-PAVSSE 4036
Query: 1058 --QPPAQQQIPSGSFAPSSQSQAYERNAPQDVSYNYSGD 1094
+ P+ Q + + +S A E P +V + SGD
Sbjct: 4037 ATEGPSTHQGGPLAIGTTPESMATE---PGEVKPSLSGD 4072
Score = 72.4 bits (176), Expect = 2e-12
Identities = 229/1031 (22%), Positives = 369/1031 (35%), Gaps = 171/1031 (16%)
Query: 155 IMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGME--AINNLPSNMPL 212
I L+ V++ L +P G Q F P S+ + G+ A++ LP P
Sbjct: 2878 IELRHNVQKGLGPGGTPFPG--QGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKP- 2934
Query: 213 PSASPLHQLDLK---------PSLPLQNSGTHTPGLLEDLSKNG--RLPEIKLPVNGCSD 261
SA P +L+ P+LP + P +L + L KLP C D
Sbjct: 2935 -SAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLP---CED 2990
Query: 262 --LEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELI-----D 314
L+D F ++ + +E +D ++ ++ ++ ND +L+ D
Sbjct: 2991 PELDDDFDAHKALEDDEELAHLGLGVDVAKGD--DELGTLENLETNDPHLDDLLNGDEFD 3048
Query: 315 ELANTVPE---DDIQDLFNEDFE------EKKEPEFSQPATET-PLSQESASVKSDPSHS 364
LA T PE D +D+FNE EK E E E PL E + +
Sbjct: 3049 LLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASE 3108
Query: 365 PFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASS--PANCAVQSPQT-- 420
P + + + G S + P V PAA + P + S T
Sbjct: 3109 PRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRM 3168
Query: 421 -----PNQAHTPGQAPPRPGNG---YLLNPAAVTVAGSAS---------GPVAVPSSDMS 463
+ HT +A G +LL P+ ++ G +S G + +P +
Sbjct: 3169 GTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAA 3228
Query: 464 PAEQLKQMAAQQ-------------QQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQ 510
++L +M + + K +Q+KQQ Q Q QQQQQQQQQ +
Sbjct: 3229 SGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSA 3288
Query: 511 TSNWSPLGPP---SSPYGAAFTAEKPNSPMMYPQAFNNQNPIVP--PMANNLQKTTMNNY 565
+ P SSP A + ++ + + + P++P P A+ LQ+ +
Sbjct: 3289 PGPAQAMSLPHEGSSP-SLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPS- 3346
Query: 566 LPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLM 625
M M++ Q + L+ QH G L + Q+ + PV + M
Sbjct: 3347 -----MAMVSNQGH-----MLSGQH-----GGQAGL------VPQQSSQPVLSQKPMGTM 3385
Query: 626 PYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQ----KRLLLMKQKGVMNQPMAY 681
P + QQ QQQ P L A D K + L K VM Q
Sbjct: 3386 PPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIG 3445
Query: 682 AALPSHGQEQHPVGLPRTTGP---MQSSVPPGSGGMVSGASPAGP---------GFLGSQ 729
A + Q+ + + GP +Q+ V GSG S P+ P G +
Sbjct: 3446 VAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEA 3505
Query: 730 PQAAIMK-----QMLIDQRAQLIEQQ-------KQQFLREQRQQQQQ------------- 764
Q + Q L+ + +++E+Q ++ +QR ++
Sbjct: 3506 DQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLK 3565
Query: 765 ---QQQILAEQQLQQSHLPRQH----LQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQS 817
+QQ ++QL Q ++ + RN QQ Q Q Q A + AL
Sbjct: 3566 LVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVL----ALSP 3621
Query: 818 MRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQML 877
++ RL+ + G + G P + L P QPG ++T + Q
Sbjct: 3622 SQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQ 3681
Query: 878 QHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPR 937
Q + G GP + + S S L+ Q Q + +
Sbjct: 3682 QQQHSGGA----GSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQ 3737
Query: 938 PQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQ-- 995
Q + Q L+G V + QQ+ QG +T+ LGP G P + Q L +Q
Sbjct: 3738 QQQQQQQQHLLGQV-----AIQQQQQQGPGVQTNQALGPKPQGL-MPPSSHQGLLVQQLS 3791
Query: 996 -HFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQG-TSQARPMVMSGLSQGVPGM 1053
PQG + A ++ +P A+G P P +Q +Q+R + L+Q G+
Sbjct: 3792 PQPPQGPQGMLGPAQVAVLQQQHPGALG----PQGPHRQVLMTQSRVLSSPQLAQQGQGL 3847
Query: 1054 PAFSQPPAQQQ 1064
AQQQ
Sbjct: 3848 MGHRLVTAQQQ 3858
Score = 43.1 bits (100), Expect = 0.001
Identities = 77/315 (24%), Positives = 121/315 (38%), Gaps = 48/315 (15%)
Query: 343 QPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPA 402
+P+ + P+ Q P H +H G +P S+ TV+T PS +P
Sbjct: 2544 EPSLKPPVPQPGLP----PPHGINSHFGPGPTLGKPQSTN---YTVATGNFHPS--GSPL 2594
Query: 403 APNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYL--LNPAAVTVAGSASGPVAV--- 457
P+ S+ + + SP P P PP +G L L+ A +G S PV
Sbjct: 2595 GPSSGSTGESYGL-SPLRP-----PSVLPPPAPDGSLPYLSHGASQRSGITS-PVEKRED 2647
Query: 458 PSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQ-------QQQQQQQQQQQHSNQ 510
P + M + ++ Q + Q + ++Q+Q+Q+ QQ Q+ +Q+
Sbjct: 2648 PGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETA 2707
Query: 511 TSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNH 570
+ +GPP S +GA +P+SP AF + P A K+++ P
Sbjct: 2708 AAAAGAVGPPGS-WGA-----EPSSP-----AFEQLSRGQTPFAGTQDKSSLVGLPPSKL 2756
Query: 571 MNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQ 630
I LG S + P T + D++ R + PY
Sbjct: 2757 SGPI------LGPGSFPSDDRLSR--PPPPATPSSMDVNSRQLVGGSQAFYQRA-PYPGS 2807
Query: 631 QQQQQQQQQQQQQQQ 645
QQQQQQ QQQQ
Sbjct: 2808 LPLQQQQQQLWQQQQ 2822
Score = 42.0 bits (97), Expect = 0.003
Identities = 50/241 (20%), Positives = 94/241 (39%), Gaps = 30/241 (12%)
Query: 322 EDDIQDLFNEDFEEKKEPE---FSQPATETPLSQ--ESASVKSDPSHSPFAHVSMGSPQA 376
E ++ NE+ PE S P E+P S E++ + P P + + +
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486
Query: 377 RPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGN 436
RP P P +P +P P SSP + +SP +P P ++PP P
Sbjct: 487 RPLEESP---------LSPPPEESPLSPPPESSPFSPLEESPLSP-----PEESPPSPAL 532
Query: 437 GYLLNP---AAVTVAGSASGPVAVPSSDM--SPAEQLKQMAAQQQQRAKLMQQKQQQQQQ 491
L+P A+ P++ P ++ SP + +++ ++ + + ++
Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE-SPMSPPPEESPMS 591
Query: 492 QQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVP 551
+ + ++ + SPL PP P + + +SPM P ++P+ P
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPP--PEASRLSPPPEDSPMSPPP---EESPMSP 646
Query: 552 P 552
P
Sbjct: 647 P 647
Score = 39.3 bits (90), Expect = 0.021
Identities = 48/209 (22%), Positives = 77/209 (36%), Gaps = 23/209 (11%)
Query: 336 KKEPEFSQPATET-PLS-----QESASVKSDPSHSPFAHVSMGS-PQARPSSSGPPFSTV 388
++ P + +P T+T PL Q P P + G PQ P PP +
Sbjct: 4238 RQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPP-GAL 4296
Query: 389 STATSLPSVASTP--AAPNPASSPANCAVQSPQTPNQAHTPGQAP--PRPGNGYLLNPAA 444
ST L V TP ++P P+ S Q P +A P P P+P L P
Sbjct: 4297 STGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPG 4356
Query: 445 VTVAGSASGPVAVPSSDMSPAEQLKQMA-AQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQ 503
+A + S + P + +A Q+ +++ L+ Q Q + Q +
Sbjct: 4357 RVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIK 4416
Query: 504 QQ----------QHSNQTSNWSPLGPPSS 522
Q+ Q + +N P+G P +
Sbjct: 4417 QEPREEPCALGAQSVKREANGEPIGAPGT 4445
Score = 37.4 bits (85), Expect = 0.081
Identities = 106/478 (22%), Positives = 164/478 (34%), Gaps = 64/478 (13%)
Query: 339 PEFSQPATET-PLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSV 397
P+ +P + T P +Q + + P P P++ PS PFS V + S
Sbjct: 2366 PDIFRPGSYTDPYAQPPLTPRPQPP--PPESCCALPPRSLPSD---PFSRVPASPQSQSS 2420
Query: 398 ASTPAAPNPASSPANCAVQSPQTP-----------------NQAHTPGQAPPRPGN---G 437
+ +P P P S+ A C SP TP P PPRP
Sbjct: 2421 SQSPLTPRPLSAEAFC--PSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVA 2478
Query: 438 YLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQ 497
+ A T G+ P A+P+ PA +L Q + +
Sbjct: 2479 FKAGSLAHTSLGAGGFPAALPA---GPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMR 2535
Query: 498 QQQQQQQQQHSNQTSNWSPLGPP----SSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPM 553
Q + S + P PP +S +G T KP S Y A N +P P+
Sbjct: 2536 FTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQS-TNYTVATGNFHPSGSPL 2594
Query: 554 ANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPL-------THFNA 606
+ T + L + P G+ G T P+ T +
Sbjct: 2595 GPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGS 2654
Query: 607 DLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRL 666
L+ P +P + L ++Q+Q+Q+ ++ +QQ L+ Q++
Sbjct: 2655 SLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLR---------QEKE 2705
Query: 667 LLMKQKGVMNQPMAYAALPSH-GQEQHPVGLPRTTGPMQSS----VPPG--SGGMVSGAS 719
G + P ++ A PS EQ G G S +PP SG ++ S
Sbjct: 2706 TAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGS 2765
Query: 720 PAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLRE----QRQQQQQQQQILAEQQ 773
L P A M ++ R QL+ + + R QQQQQQ+ +QQ
Sbjct: 2766 FPSDDRLSRPPPPATPSSMDVNSR-QLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQ 2822
Score = 36.2 bits (82), Expect = 0.18
Identities = 55/231 (23%), Positives = 77/231 (33%), Gaps = 40/231 (17%)
Query: 338 EPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSV 397
EP S+P E PLS + PS P + P P PP S + TA + P++
Sbjct: 897 EPALSEPG-EPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP----PPLSPIITAAAPPAL 951
Query: 398 ASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAV 457
+ P + + +SP TP PP +P V P+ +
Sbjct: 952 SPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEAN---CTDPEPVP-------PMIL 1001
Query: 458 PSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQT---SNW 514
P S SP + LM+ Q Q Q Q S S
Sbjct: 1002 PPSPGSPVGPASPI---------LMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052
Query: 515 SPLGPPSSPYGAAFTAE----------KPNSPMMYPQAFNNQNPIVPPMAN 555
SPL P G + AE +P P + P A +P+ PM +
Sbjct: 1053 SPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSA---TSPLPSPMGD 1100
Score = 34.7 bits (78), Expect = 0.53
Identities = 62/331 (18%), Positives = 119/331 (35%), Gaps = 38/331 (11%)
Query: 337 KEPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPS 396
+E S P E+P+S + + P PF + P S PP ++ + S
Sbjct: 577 EESPMSPPPEESPMSPPPEASRLFP---PFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633
Query: 397 VASTPAAPNPASSPANCAVQSP------QTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGS 450
S P +P S P + SP +P +P PP A+
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP 693
Query: 451 ASGPVAVPSSDM----SPAEQLKQMAAQQQQRAKLMQQKQQQQQQQ------QQQQQQQQ 500
P + P D P + L + ++ L ++ Q + + + ++
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLS 753
Query: 501 QQQQQQHSNQTSNWSPLGP-PSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQK 559
+ ++ H + + L P P P A P P + PQA + P + P L
Sbjct: 754 PRPEEPHLSPQAEEPHLSPQPEEPCLCAV----PEEPHLSPQA---EGPHLSPQPEELH- 805
Query: 560 TTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANP 619
++ + H++ + ++P S + + L+ + +P + S ++P + P
Sbjct: 806 --LSPQTEEPHLSPVPEEP----CLSPQPEESHLSPQSEEPCLSPRPEES-HLSPELEKP 858
Query: 620 NKNPLMPYIQQQQQQQQQQQQQQQQQQPPPP 650
PL P ++ ++ Q ++ PPP
Sbjct: 859 ---PLSPRPEKPPEEPGQCPAPEELPLFPPP 886
Score = 34.7 bits (78), Expect = 0.53
Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 22/157 (14%)
Query: 350 LSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASS 409
L QES + + HS +VS + R S+ PP PS +P AP+PAS
Sbjct: 4879 LKQESPAPEPPTQHSYTYNVS--NLDVRQLSAPPPEE--------PSPPPSPLAPSPASP 4928
Query: 410 PANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVP--SSDMSPAEQ 467
P V+ P P A P +P P A + + P A P + S +
Sbjct: 4929 PTEPLVELPTEP-LAEPPVPSP---------LPLASSPESARPKPRARPPEEGEDSRPPR 4978
Query: 468 LKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ 504
LK+ + +R +L+ Q+ +Q+ +++ + +Q
Sbjct: 4979 LKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQ 5015
Score = 32.3 bits (72), Expect = 2.6
Identities = 139/713 (19%), Positives = 230/713 (32%), Gaps = 117/713 (16%)
Query: 339 PEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVA 398
P F + + +E S PS+ P + SP + G T P V
Sbjct: 2276 PPFGESRKALEVKKEELGASS-PSYGPPNLGFVDSPSSGTHLGGLELKT-------PDVF 2327
Query: 399 STPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPR-------PGNGYLLNPAAVTVAGSA 451
P P + PQ+P P + PP P + + P GS
Sbjct: 2328 KAPLTPRASQV-------EPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRP------GSY 2374
Query: 452 SGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQT 511
+ P A P P + R+ + Q Q Q + S +
Sbjct: 2375 TDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEA 2434
Query: 512 SNWSPLGP------PSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNN- 564
SP+ P P S + + P +P+ P Q P V A +L T++
Sbjct: 2435 FCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP--RPQPPEVAFKAGSLAHTSLGAG 2492
Query: 565 ----YLPQNHMNMINQQ-PNNLGTNSLNKQHNILTYGNTKPL--THFNADLSQRMTPPVA 617
LP ++ + P+ N + G P+ T A + PPV
Sbjct: 2493 GFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP 2552
Query: 618 NPNKNP-------LMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMK 670
P P P + Q P L P + + + L ++
Sbjct: 2553 QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPL-GPSSGSTGESYGLSPLR 2611
Query: 671 QKGVMNQPMAYAALP--SHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGS 728
V+ P +LP SHG Q T P++ PG+G S A+ PG
Sbjct: 2612 PPSVLPPPAPDGSLPYLSHGASQRS----GITSPVEKREDPGTGMGSSLATAELPGT--Q 2665
Query: 729 QPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQR 788
P + + Q + E+++Q+Q+ +++L QQ+Q++ L ++
Sbjct: 2666 DPGMSGLSQTEL----------------EKQRQRQRLRELLIRQQIQRNTLRQEKETAAA 2709
Query: 789 NPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRL----MAQNAGMMGIGPSQNPGTM-- 842
V G P A S A + + + + ++G+ PS+ G +
Sbjct: 2710 AAGAV-------GPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILG 2762
Query: 843 -ATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQML--QHPNQSGMSITHNQAQGPRQ-- 897
+ + + P TP+S G +Q + P + + Q Q +Q
Sbjct: 2763 PGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQ 2822
Query: 898 --PASGQGVGMVSGFGQS-------MLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLM 948
A+ M + F + + S + ++ GP G+ +P P P + L
Sbjct: 2823 ATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGP-GEPVPGPAGPAQFIELR 2881
Query: 949 GTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGL 1001
VQ+G G G GP YP+ RL P+GL
Sbjct: 2882 HNVQKGL---------GPGGTPFPGQGPPQRPRFYPVSEDPHRLA----PEGL 2921
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 95.9 bits (237), Expect = 2e-19
Identities = 183/786 (23%), Positives = 254/786 (32%), Gaps = 145/786 (18%)
Query: 378 PSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNG 437
P +SGP ++ P+ P N +SS P Q TP A
Sbjct: 166 PMASGPGIIRMNN----PATVMIPPGGNVSSS---MMAPGPNPELQPRTPRPASQSDAMD 218
Query: 438 YLLNPAAVTVAGSASGPVAVPSSDMSPAE-----------QLKQMAAQQQQRAKLMQQKQ 486
LL+ + SG +A P M P QL+Q QQQQ+ + QQ+Q
Sbjct: 219 PLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQ 278
Query: 487 QQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNN- 545
QQQQQQQ Q + QQ QQQQ ++ P P + + P+ + P A +
Sbjct: 279 QQQQQQQLQARPPQQHQQQQPQGIRPQFT--APTQVPVPPGWN-QLPSGALQPPPAQGSL 335
Query: 546 ----------QNPIVPPMANNLQ-KTTMNNYLPQNHMNMINQQPNNLGTNSLNKQH-NIL 593
+ P+ PM LQ + ++ +H P G+ ++ H N
Sbjct: 336 GTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSH----PPPPYPFGSQQASQAHTNFP 391
Query: 594 TYGN----TKPLTHFNADLSQRMTPPVANP---NKNPLMPYIQQQQ----------QQQQ 636
N T P R+ P+ P NK+P QQ Q QQ
Sbjct: 392 QMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQ 451
Query: 637 QQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL 696
Q + Q P P Q P + + M Q+G N P + + Q P L
Sbjct: 452 QMGPRPPQNNPLPQGFQQPVSSPGRNP-----MVQQG--NVPPNFMVMQQQPPNQGPQSL 504
Query: 697 PRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLR 756
G M +PPG A A P F+ Q + QL Q Q
Sbjct: 505 HPGLGGMPKRLPPG-----FSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAG 559
Query: 757 EQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQ 816
Q Q Q+Q SH P +QP + + Q
Sbjct: 560 GQGAGPPQ-------NQMQVSHGPPNMMQP------------------SLMGIHGNMNNQ 594
Query: 817 SMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMT-- 874
TS + N M P Q P + Q + P Q G N M
Sbjct: 595 QAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQ---IVPSQGQMVQQQGTLNPQNPMILS 651
Query: 875 --------QMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQ 926
QM+ +P + + + P+Q S QG M++ H Q
Sbjct: 652 RAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMA--------------PHNQ 697
Query: 927 MKGPVGQALPRPQAPPRLQSLMGTVQQG--AQSWQQRSLQGMPGRTSGELGPFNNGASYP 984
M GP GQ L Q P ++ +M QG Q Q MPG GP N
Sbjct: 698 MMGPQGQVL--LQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPN----- 750
Query: 985 LQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMS 1044
+Q + T Q Q L Q G V MG Q P A+
Sbjct: 751 MQGNMVQFTGQMSGQMLPQQ------GPVNNSPSQVMGIQGQVLRPPGPSPHMAQ----- 799
Query: 1045 GLSQGVPGMPAFSQPPAQQQIPSGSFAPSS----QSQAYERNAPQDVSYNYSGDGAGGSF 1100
G P A + Q +P S ++ QA + N+ ++ G F
Sbjct: 800 --QHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPF 857
Query: 1101 PGLPDG 1106
G P+G
Sbjct: 858 SGAPNG 863
Score = 50.4 bits (119), Expect = 9e-06
Identities = 77/353 (21%), Positives = 113/353 (32%), Gaps = 44/353 (12%)
Query: 377 RPSSSGPPFSTVSTATSLPSVASTPAA-------PNPASSPANCAVQSPQTPNQAHTPGQ 429
+P PP ++ L + + PA P P N P+ P ++ P
Sbjct: 913 KPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPG 972
Query: 430 APPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQ 489
P +P L + + P P +Q + QQQQ Q + QQQ
Sbjct: 973 YPSQPVEQRPLQQMPPQLMQHVAPP------PQPPQQQPQPQLPQQQQPPPPSQPQSQQQ 1026
Query: 490 QQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPI 549
QQQQQQ QQ S + + PP P P + Q P
Sbjct: 1027 QQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPA 1086
Query: 550 VPPMANNLQKTTM--NNYLPQNHMNMINQQ-PNNLGTNSLNKQHNILTYGNTKPLTHFNA 606
P + + Q+ M N L N M+ Q+ P N ++ L + ++
Sbjct: 1087 SVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASL-------------P 1133
Query: 607 DLSQRMTPPV-ANPNKNPLMPYIQQQQQQQQ---------QQQQQQQQQQPPPPQLQAPR 656
+ S P V PN P + Q Q Q QQPP L +
Sbjct: 1134 EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSH 1193
Query: 657 AHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPP 709
H + + N+ A P Q P P +T P + S+ P
Sbjct: 1194 GHHFPNVAAPTQTSRPKTPNR-----ASPRPYYPQTPNNRPPSTEPSEISLSP 1241
Score = 50.1 bits (118), Expect = 1e-05
Identities = 156/750 (20%), Positives = 248/750 (33%), Gaps = 147/750 (19%)
Query: 429 QAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQL----KQMAAQQ--------- 475
Q P N +L+ A + G V PS ++ P+ Q KQM +QQ
Sbjct: 639 QGTLNPQNPMILSRAQLMPQGQMM--VNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHN 696
Query: 476 -----QQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPL--GPPSSPYGAAF 528
Q + L Q +Q Q Q +QQ Q SN + + GP + G
Sbjct: 697 QMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMV 756
Query: 529 TAEKPNSPMMYPQAFNNQNPI--VPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSL 586
S M PQ Q P+ P +Q + P HM + P N +
Sbjct: 757 QFTGQMSGQMLPQ----QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDV 812
Query: 587 N----------KQHNILT------YGNTKPLTHFNADLSQRMTPPVANPNKN-------- 622
+ +Q N++ GN+ HF+ P PN N
Sbjct: 813 SLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNP 872
Query: 623 ------------PLMPYIQQQQ---------QQQQQQQQQQQQQQPPPPQLQAPRAHLS- 660
PL+ + Q +Q + +++ PP + + + L+
Sbjct: 873 GFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNT 932
Query: 661 --------EDQKRLLLMKQKGV------------MNQPMAYAALPSHGQEQHPVGLPRTT 700
E+ + L ++G+ N+P Y PS EQ P+
Sbjct: 933 PDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGY---PSQPVEQRPL------ 983
Query: 701 GPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQ 760
+PP M A P P QPQ +Q + Q +QQ+QQ
Sbjct: 984 ----QQMPPQL--MQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML 1037
Query: 761 QQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAAL----- 815
QQ + + Q H PR L P P+QQ GS + +++ A++
Sbjct: 1038 MMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQ----SGSVPVMVSLQGPASVPPSPD 1093
Query: 816 ---QSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTG 872
M + + N+ M S + + A + + A S P+ G NM +
Sbjct: 1094 KQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSH 1153
Query: 873 MT-----QMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQM 927
+ M+ P ++ Q P+QP + S G N A Q +
Sbjct: 1154 VVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVN---SLPSSHGHH-FPNVAAPTQTSRP 1209
Query: 928 KGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGEL-GPFNNGASYPLQ 986
K P +A PRP P T S + + P R + + G F + PL
Sbjct: 1210 KTP-NRASPRPYYPQ-------TPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLP 1261
Query: 987 AGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMSGL 1046
+P L + QGL N T++ + A M PS T + +V++
Sbjct: 1262 P-RPNLNRGFDQQGL-------NPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSG 1313
Query: 1047 SQGVPGMPAFSQPPAQQQIPSGSFAPSSQS 1076
Q G + P ++ GS ++ S
Sbjct: 1314 KQSNSGATKRASPSNSRRSSPGSSRKTTPS 1343
Score = 35.0 bits (79), Expect = 0.40
Identities = 68/320 (21%), Positives = 114/320 (35%), Gaps = 50/320 (15%)
Query: 237 PGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSET------ 290
P L L N P + + G +DLE + ++ +DLK+ + PT D S +
Sbjct: 1488 PTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASV-IPTLQDLSSSKEPSNS 1546
Query: 291 -SLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEP-EFSQPATET 348
+L + N+L S +L E E+ +A ++P + + + P + + T
Sbjct: 1547 LNLPHSNELCS--SLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPPNQITVFVTSN 1604
Query: 349 PLSQESASVKSDPSHSPFAHV-------------------SMGSPQARPSSSGPPFSTVS 389
P++ + + + P+H A + S ARP P F S
Sbjct: 1605 PITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSAAQSNARPQFITPVFINSS 1664
Query: 390 TAT-----SLPS-VASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPA 443
+ S PS + + P N P + AV P Q + + P P N +PA
Sbjct: 1665 SIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQ-NIKFSSAPVPPNALSSSPA 1723
Query: 444 ------AVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQ 497
V S + PV +PS + + + + Q K+ + Q
Sbjct: 1724 PNIQTGRPLVLSSRATPVQLPSPPCTSSPVV-------PSHPPVQQVKELNPDEASPQVN 1776
Query: 498 QQQQQQQQQHSNQTSNWSPL 517
Q S T+ SPL
Sbjct: 1777 TSADQNTLPSSQSTTMVSPL 1796
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 88.6 bits (218), Expect = 3e-17
Identities = 149/597 (24%), Positives = 212/597 (35%), Gaps = 115/597 (19%)
Query: 343 QPATETPLSQESASVKSDPSHSP--FAHVSMGSPQARPSSSGPPFSTVSTATSLPSVAST 400
QP +T A K+ P+ + A V G+ + + + P VS + ++A
Sbjct: 2546 QPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGV 2605
Query: 401 PAAPNPASSPANCAVQSPQTPNQAHTPG----------QAPPRP-GNGYLLNPAAVTVAG 449
PAA N + SP P TPG Q PPR G+ P V++A
Sbjct: 2606 PAA---TFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMAT 2662
Query: 450 SAS-----------------GPVAVPSSDMSPAEQLKQMAAQQQQRAKL---------MQ 483
+ PV P+ + P Q+ Q Q + Q
Sbjct: 2663 TQGVRAVTSVTASAVVTTNLTPVQTPARSLVP--QVSQATGVQLPGKTITPAHFQLLRQQ 2720
Query: 484 QKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPL------GPPSSPYGAAFTAEKPNSPM 537
Q+QQQQQQQQQQQQQQQQQQQQQ QT+ S + G SP + +
Sbjct: 2721 QQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHL 2780
Query: 538 MYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGN 597
+ Q Q P PP Q + QQ + T + L G
Sbjct: 2781 IKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGT 2840
Query: 598 TKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRA 657
T N +++ P + +Q Q Q Q Q Q Q PP + P A
Sbjct: 2841 TVA----NLQVARLTRVPTSQ---------LQAQGQMQTQAPQPAQVALAKPPVVSVPAA 2887
Query: 658 HLSEDQKRLLLMKQKGV---MNQPMAYA-----ALPSHGQE-----QHPVGLPRTTGPMQ 704
+S L M G+ + QP A A P H Q+ Q V + P
Sbjct: 2888 VVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQA 2947
Query: 705 SSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLR---EQRQQ 761
+ P ++ P G+Q + A Q + K QFL Q Q+
Sbjct: 2948 AQGPAAVQQKITAQQITTP---GAQQKVAYAAQPAL----------KTQFLTTPISQAQK 2994
Query: 762 QQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQF--QGSPQDIAAVRSQAALQSMR 819
QQ+ + Q+Q + LP Q +Q Q +QQV Q SPQ +A ++ AA Q ++
Sbjct: 2995 LAGAQQV--QTQIQVAKLP-QVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQ 3051
Query: 820 ------------TSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQP 864
+L+ Q P Q PG A + S +P+ QP
Sbjct: 3052 MIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPAS------SDSPSQQP 3102
Score = 46.6 bits (109), Expect = 1e-04
Identities = 51/194 (26%), Positives = 76/194 (39%), Gaps = 14/194 (7%)
Query: 339 PEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVA 398
P P T P + +A P A S +P+A+ +++ PF T + S P
Sbjct: 1444 PSTHPPRTAAPTTASAAPQGPLRGRPPIATFS-ANPEAKAAAA--PFQTSQASASAPR-H 1499
Query: 399 STPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRP-----GNGYLLNPAAVTVAGSASG 453
+A + A+SPA+ A QT QA TPGQ PP+P G P + + A
Sbjct: 1500 QPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQ- 1558
Query: 454 PVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQ---QQQQQQQQQQQQQHSNQ 510
+PS ++ QL + Q + A+ Q Q + Q +Q Q Q
Sbjct: 1559 -ARLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPLQLQ 1617
Query: 511 TSNWSPLGPPSSPY 524
S + P PY
Sbjct: 1618 GSVLQIVSAPGQPY 1631
Score = 34.7 bits (78), Expect = 0.53
Identities = 160/735 (21%), Positives = 235/735 (31%), Gaps = 147/735 (20%)
Query: 401 PAAPNPASSPA-----NCAVQSPQTPNQ--AHTPGQAPPRPGNGYLLNPAAVTVAGSASG 453
PA PNP SPA + + +PQ+P+ ++P N + + V G
Sbjct: 29 PAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQLMNRSPATGQNVNITLQSVGPVVGGNQQ 88
Query: 454 PVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSN 513
P SP Q +AQ ++ Q QQ Q Q Q Q
Sbjct: 89 ITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSPLSQQVQTQSPTQPSPGPGQALQ 148
Query: 514 WSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNL------------QKTT 561
G P G + P + Q + P + Q
Sbjct: 149 NVRAGAPGP--GLGLCSSSPTGGFVDASVLVRQISLSPSSGGHFVFQDGSGLTQIAQGAQ 206
Query: 562 MNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPN- 620
+ P + + ++P+ T S H++ G P A L P+A+P+
Sbjct: 207 VQLQHPGTPITVRERRPSQPHTQSGGTIHHL---GPQSPAAAGGAGLQ-----PLASPSH 258
Query: 621 --KNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQP 678
L P I Q Q QQQQ Q P P L R +LL G
Sbjct: 259 ITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERT------PGVLLPGAGGAAGFG 312
Query: 679 MAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQM 738
M P T P +++VPPG +S G G + +++
Sbjct: 313 M--------------TSPPPPTSPSRTAVPPG----LSSLPLTSVGNTGMKKVPKKLEE- 353
Query: 739 LIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQ 798
I + + Q ++Q L Q+ Q +++ E ++ L QH
Sbjct: 354 -IPPASPEMAQMRKQCLDYHYQEMQALKEVFKEYLIELFFL--QH--------------- 395
Query: 799 FQGSPQDIAAVRSQ--AALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPY 856
FQG+ D A + + A LQ+ L + + + + E LA
Sbjct: 396 FQGNMMDFLAFKKKHYAPLQAY----LRQNDLDIEEEEEEEEEEEEKSEVINDEQALAGS 451
Query: 857 STTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLV 916
+ T + + Q +GM+ Q++ PR QGV
Sbjct: 452 LVAGAGS----TVETDLFKRQQAMPSTGMA---EQSKRPRLEVGHQGV------------ 492
Query: 917 NSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGP 976
QHP V P Q P Q M Q AQ QR Q ++G P
Sbjct: 493 ----VFQHPGADAGV----PLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGP--P 542
Query: 977 FNNGASYPLQAGQPRLTKQHFPQGL-------------SQSVVDANTG---TVRTLN--- 1017
N AS L P+L + P G+ VV+A T V+T
Sbjct: 543 VQNAAS--LHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNV 600
Query: 1018 --PAAMGRQM--MPSLPGQ-------QGTSQARPMVMSGLSQGVPG--MPAFSQPPAQQQ 1064
PA Q+ PS P Q G Q + +S L Q V +P PP +
Sbjct: 601 PIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRP 660
Query: 1065 IP---SGSFAPSSQS 1076
+P + S AP S S
Sbjct: 661 LPTSSTSSLAPVSGS 675
Score = 31.2 bits (69), Expect = 5.8
Identities = 75/363 (20%), Positives = 118/363 (32%), Gaps = 59/363 (16%)
Query: 743 RAQLIEQQKQQFLREQRQQQ-----------------QQQQQILAEQQLQQSHLPR--QH 783
RA+ I ++K+ +Q+ QQ QQ L + Q S P
Sbjct: 2481 RAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPA 2540
Query: 784 LQPQRNPYPVQQVNQFQGSPQDIAA-VRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTM 842
+QPQ P P Q PQ + A ++Q A+ + ++ ++A G S G +
Sbjct: 2541 VQPQPQPQP-------QTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAV 2593
Query: 843 ATAAAQSEMGLAPYST---------TPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQ 893
+ + + P +T +P + + + H ++
Sbjct: 2594 SGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATA 2653
Query: 894 GPR--QPASGQGVGMVSGFGQSMLVNSAITQQH-------PQMKGPVGQALPRPQAPPRL 944
P A+ QGV V+ S +V + +T PQ+ G LP P
Sbjct: 2654 TPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAH 2713
Query: 945 QSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQ-HFPQGLSQ 1003
L+ QQ Q QQ+ Q + + Q Q T Q PQ Q
Sbjct: 2714 FQLLRQQQQQQQQQQQQQQQQQQQQQQQQ-----------QQQQQTTTTSQVQVPQIQGQ 2762
Query: 1004 SVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQ 1063
+ A V L P + + L Q P S Q + + P QQ
Sbjct: 2763 AQSPAQIKAVGKLTPEHLIKMQKQKL--QMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQ 2820
Query: 1064 QIP 1066
Q P
Sbjct: 2821 QSP 2823
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 82.4 bits (202), Expect = 2e-15
Identities = 139/594 (23%), Positives = 196/594 (32%), Gaps = 108/594 (18%)
Query: 334 EEKKEPEFSQPATE---TPLSQESASVKSDPSHSPFAHVSMGSP----QARPSSSGPPFS 386
++ P+ QP + +P+S A S P VS G P A P + PP +
Sbjct: 1857 QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPA 1916
Query: 387 TVSTATSLPSVA----------------------STPA---APNPASSPANCAVQSPQTP 421
V A + A TP AP + P V P P
Sbjct: 1917 AVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMP 1976
Query: 422 NQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVP-SSDMSPAEQLKQMAAQQQQRAK 480
+ Q P P + ++ A VA P + P + A Q R
Sbjct: 1977 SMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTL 2036
Query: 481 LMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYP 540
QQQQQ + Q +T+ + P P + P M P
Sbjct: 2037 KSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGL-----QSQPGMQP 2091
Query: 541 QAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKP 600
Q +Q P + + N +Q +P M P N +N HN
Sbjct: 2092 QPGMHQQPSLQNL-NAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHN--------- 2141
Query: 601 LTHFNADLSQRMTPPVA--NPNKNPLM--PYIQQQQQQQQQQQQQQQQQQPPPPQLQAPR 656
P +A NP ++ +QQQQQQQQQQQQQQQQQQ
Sbjct: 2142 -------------PNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMA 2188
Query: 657 AHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVS 716
H G QP P Q+Q MQ +P M
Sbjct: 2189 GH--------------GQFQQPQGPGGYPPAMQQQQ---------RMQQHLPLQGSSM-- 2223
Query: 717 GASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQ 776
G A G LG Q + D + QQ L+++ QQQQ +Q +
Sbjct: 2224 GQMAAQMGQLGQMGQPGLG----ADSTPNI-----QQALQQRILQQQQMKQQIGSPGQPN 2274
Query: 777 SHLPRQHL---QPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGI 833
P+QH+ QPQ + P QQ+ + VRS A +QS R ++ I
Sbjct: 2275 PMSPQQHMLSGQPQASHLPGQQIATSLSN-----QVRSPAPVQSPRPQSQPPHSSPSPRI 2329
Query: 834 GPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYN-MSTGMTQMLQHPNQSGMS 886
P +P ++ GLA + Q + N + M L P++S +S
Sbjct: 2330 QPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALS 2383
Score = 79.0 bits (193), Expect = 2e-14
Identities = 139/593 (23%), Positives = 205/593 (34%), Gaps = 116/593 (19%)
Query: 404 PNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMS 463
P+P S+P Q P TP P Q P +P +++ AG S P + +S
Sbjct: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQP--------SPVSMSPAGFPSVARTQPPTTVS 1896
Query: 464 PAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSP 523
+ Q+ A + +Q +++ QQQQ + +++ + +G P S
Sbjct: 1897 TGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQ 1956
Query: 524 YG-AAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPN-NL 581
+ +PN P++P M + LPQ QQP L
Sbjct: 1957 MAPVSLNVPRPNQV---------SGPVMPSMPPGQWQQAP---LPQ-------QQPMPGL 1997
Query: 582 GTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQ 641
++ Q G P +S + K+P P QQQQQ
Sbjct: 1998 PRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSP----------QQQQQ 2047
Query: 642 QQQQQPPPPQLQAPRAHLSEDQKRLL-----LMKQKGVMNQPMAYAALPSHGQEQHPVGL 696
PQL A A + + + + + Q G+ +QP P G Q P
Sbjct: 2048 VLNILKSNPQLMA--AFIKQRTAKYVANQPGMQPQPGLQSQP---GMQPQPGMHQQPS-- 2100
Query: 697 PRTTGPMQSSVP----PGSGGMVSGASPAGPGFL----GSQPQAAIMKQMLIDQ-RAQLI 747
+ MQ+ VP P + G +P G G P A M + R QL+
Sbjct: 2101 LQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLL 2160
Query: 748 EQQKQQFLREQRQQQQQQQQ--------------------------ILAEQQLQQSHLPR 781
+QQ+QQ ++Q+QQQQQQQQ + +QQ Q HLP
Sbjct: 2161 QQQQQQ--QQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPL 2218
Query: 782 QHLQPQRNPYPVQQVNQF--QGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMG----IGP 835
Q + + Q+ Q G D QA Q + + M Q G G + P
Sbjct: 2219 QGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSP 2278
Query: 836 SQN-----------PG-TMATAAAQSEMGLAP-YSTTPTSQPGMYNMSTGMTQMLQHPNQ 882
Q+ PG +AT+ + AP S P SQP + S P
Sbjct: 2279 QQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS---------PRI 2329
Query: 883 SGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQAL 935
H+ + P G V M S Q L N + PQ+ P AL
Sbjct: 2330 QPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSAL 2382
Score = 44.3 bits (103), Expect = 7e-04
Identities = 113/515 (21%), Positives = 180/515 (34%), Gaps = 76/515 (14%)
Query: 625 MPYIQQQQQQQQQQQQQQQQQQPPPPQ------------LQAPRAHLSEDQKRLLLMKQK 672
+PY+ Q Q Q Q Q QQ QP Q + P ++ DQ+ L+ +
Sbjct: 452 LPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISES 511
Query: 673 GVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQ--- 729
+ A L + G +G T + ++ PP S G+ G L S
Sbjct: 512 ALPTSLGATNPLMNDGSNSGNIG---TLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVH 568
Query: 730 ---------PQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAE------QQL 774
P A +K ++ ++ + + E + + +LAE ++L
Sbjct: 569 KLVQAIFPTPDPAALKDRRMENLVAYAKKVEGD-MYESANSRDEYYHLLAEKIYKIQKEL 627
Query: 775 QQSHLPRQHLQPQRNPYPVQQVNQFQGS--PQDIAAVRSQAALQSMRTSRLMAQNA---- 828
++ R H Q P Q PQ VR S+ +R+
Sbjct: 628 EEKRRSRLHKQGILGNQPALPAPGAQPPVIPQ-AQPVRPPNGPLSLPVNRMQVSQGMNSF 686
Query: 829 GMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSIT 888
M +G Q P A S M + + S PG M+ ++M Q PN G
Sbjct: 687 NPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPG---MAISPSRMPQPPNMMGAHTN 743
Query: 889 HNQAQGPRQ---------PAS--GQGVGM-----VSGFGQSMLVNSAITQQHPQMKGPVG 932
+ AQ P Q P+S VGM +G Q + +A+ M GP
Sbjct: 744 NMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNP-LNMLGPQA 802
Query: 933 QALPRP---QAPPRLQSLMGTVQQGAQSWQQRSLQGM-PGRTSGELGPFNNGASYPLQAG 988
LP P Q+P + G S Q + GM P + + P +S +G
Sbjct: 803 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSS----SG 858
Query: 989 QPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQ-MMPSLPGQQGTSQARPMVMSGLS 1047
Q T P + + +T TV+ A + Q P P T Q+ + +
Sbjct: 859 Q---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVH 915
Query: 1048 QGVPGMPAFSQPPA--QQQIPSGSFAPSSQSQAYE 1080
PG P SQ A ++P+ S S+++ + +
Sbjct: 916 AQPPGTP-LSQAAASIDNRVPTPSSVASAETNSQQ 949
Score = 41.2 bits (95), Expect = 0.006
Identities = 53/252 (21%), Positives = 94/252 (37%), Gaps = 50/252 (19%)
Query: 344 PATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSG----PPFSTVSTATSLPSVAS 399
P T S + P +P + P SSSG P +V +AT S +
Sbjct: 820 PPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPT 879
Query: 400 TPAA------PNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASG 453
AA P P + +V +PQ+ Q TP A P PG L+ AA ++
Sbjct: 880 VQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP-PGTP--LSQAAASIDNRVPT 936
Query: 454 PVAVPSSDMS--------PAEQLK----------------------------QMAAQQQQ 477
P +V S++ + P ++K Q A+Q ++
Sbjct: 937 PSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKE 996
Query: 478 RAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPM 537
+ +QK + + +++ + + + ++++ S+ S PS P F E+ +
Sbjct: 997 ETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQAL 1056
Query: 538 MYP-QAFNNQNP 548
M +A Q+P
Sbjct: 1057 MPTLEALYRQDP 1068
Score = 33.5 bits (75), Expect = 1.2
Identities = 69/295 (23%), Positives = 97/295 (32%), Gaps = 34/295 (11%)
Query: 374 PQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPR 433
PQA+P PP +S + V+ + NP S VQ PQ P G
Sbjct: 658 PQAQPVR--PPNGPLSLPVNRMQVSQGMNSFNPMSLGN---VQLPQAPM-----GPRAAS 707
Query: 434 PGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQ- 492
P N + + +V G A P +P M AQ +++ + Q Q
Sbjct: 708 PMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGA 767
Query: 493 ------QQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQ 546
Q Q Q Q + + + LGP +S + P P P +
Sbjct: 768 MSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAG 827
Query: 547 NPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNA 606
P +LQ TT P QP+ ++S Q T G+ T +
Sbjct: 828 MP-------SLQHTTPPGMTPPQPA--APTQPSTPVSSS--GQTPTPTPGSVPSATQTQS 876
Query: 607 DLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSE 661
TP V + + P Q Q Q QQQP P Q P LS+
Sbjct: 877 ------TPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQ 925
Score = 33.1 bits (74), Expect = 1.5
Identities = 60/252 (23%), Positives = 83/252 (32%), Gaps = 37/252 (14%)
Query: 339 PEFSQPATETPLSQE-SASVKSDPSHSPFAHVS-MG-SPQARPSSSGPPFSTVSTATSLP 395
P + +P+ Q + P+ + A +S MG SP ++ SS P SLP
Sbjct: 84 PGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAP---------SLP 134
Query: 396 SVASTPAAPNPASSPA---------NCAVQSPQTP------------NQAHTPGQAPPRP 434
A++ + P PA+S A A SP T NQ H PG
Sbjct: 135 KQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTH-PGLLNSNS 193
Query: 435 GNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQ-KQQQQQQQQ 493
G+ L+N A+ A +G + A Q + L + Q Q
Sbjct: 194 GHS-LINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTG 252
Query: 494 QQQQQQQQQQQQQHSNQTSNWSPLGPP-SSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPP 552
Q T N SP G P S G A N + Q+ N P P
Sbjct: 253 HAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPT 312
Query: 553 MANNLQKTTMNN 564
N T + N
Sbjct: 313 DIKNTSVTNVPN 324
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 82.4 bits (202), Expect = 2e-15
Identities = 139/594 (23%), Positives = 196/594 (32%), Gaps = 108/594 (18%)
Query: 334 EEKKEPEFSQPATE---TPLSQESASVKSDPSHSPFAHVSMGSP----QARPSSSGPPFS 386
++ P+ QP + +P+S A S P VS G P A P + PP +
Sbjct: 1895 QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPA 1954
Query: 387 TVSTATSLPSVA----------------------STPA---APNPASSPANCAVQSPQTP 421
V A + A TP AP + P V P P
Sbjct: 1955 AVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMP 2014
Query: 422 NQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVP-SSDMSPAEQLKQMAAQQQQRAK 480
+ Q P P + ++ A VA P + P + A Q R
Sbjct: 2015 SMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTL 2074
Query: 481 LMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYP 540
QQQQQ + Q +T+ + P P + P M P
Sbjct: 2075 KSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGL-----QSQPGMQP 2129
Query: 541 QAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKP 600
Q +Q P + + N +Q +P M P N +N HN
Sbjct: 2130 QPGMHQQPSLQNL-NAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHN--------- 2179
Query: 601 LTHFNADLSQRMTPPVA--NPNKNPLM--PYIQQQQQQQQQQQQQQQQQQPPPPQLQAPR 656
P +A NP ++ +QQQQQQQQQQQQQQQQQQ
Sbjct: 2180 -------------PNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMA 2226
Query: 657 AHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVS 716
H G QP P Q+Q MQ +P M
Sbjct: 2227 GH--------------GQFQQPQGPGGYPPAMQQQQ---------RMQQHLPLQGSSM-- 2261
Query: 717 GASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQ 776
G A G LG Q + D + QQ L+++ QQQQ +Q +
Sbjct: 2262 GQMAAQMGQLGQMGQPGLG----ADSTPNI-----QQALQQRILQQQQMKQQIGSPGQPN 2312
Query: 777 SHLPRQHL---QPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGI 833
P+QH+ QPQ + P QQ+ + VRS A +QS R ++ I
Sbjct: 2313 PMSPQQHMLSGQPQASHLPGQQIATSLSN-----QVRSPAPVQSPRPQSQPPHSSPSPRI 2367
Query: 834 GPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYN-MSTGMTQMLQHPNQSGMS 886
P +P ++ GLA + Q + N + M L P++S +S
Sbjct: 2368 QPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALS 2421
Score = 79.0 bits (193), Expect = 2e-14
Identities = 139/593 (23%), Positives = 205/593 (34%), Gaps = 116/593 (19%)
Query: 404 PNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMS 463
P+P S+P Q P TP P Q P +P +++ AG S P + +S
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQPPAQPQP--------SPVSMSPAGFPSVARTQPPTTVS 1934
Query: 464 PAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSP 523
+ Q+ A + +Q +++ QQQQ + +++ + +G P S
Sbjct: 1935 TGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQ 1994
Query: 524 YG-AAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPN-NL 581
+ +PN P++P M + LPQ QQP L
Sbjct: 1995 MAPVSLNVPRPNQV---------SGPVMPSMPPGQWQQAP---LPQ-------QQPMPGL 2035
Query: 582 GTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQ 641
++ Q G P +S + K+P P QQQQQ
Sbjct: 2036 PRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSP----------QQQQQ 2085
Query: 642 QQQQQPPPPQLQAPRAHLSEDQKRLL-----LMKQKGVMNQPMAYAALPSHGQEQHPVGL 696
PQL A A + + + + + Q G+ +QP P G Q P
Sbjct: 2086 VLNILKSNPQLMA--AFIKQRTAKYVANQPGMQPQPGLQSQP---GMQPQPGMHQQPS-- 2138
Query: 697 PRTTGPMQSSVP----PGSGGMVSGASPAGPGFL----GSQPQAAIMKQMLIDQ-RAQLI 747
+ MQ+ VP P + G +P G G P A M + R QL+
Sbjct: 2139 LQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLL 2198
Query: 748 EQQKQQFLREQRQQQQQQQQ--------------------------ILAEQQLQQSHLPR 781
+QQ+QQ ++Q+QQQQQQQQ + +QQ Q HLP
Sbjct: 2199 QQQQQQ--QQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPL 2256
Query: 782 QHLQPQRNPYPVQQVNQF--QGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMG----IGP 835
Q + + Q+ Q G D QA Q + + M Q G G + P
Sbjct: 2257 QGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSP 2316
Query: 836 SQN-----------PG-TMATAAAQSEMGLAP-YSTTPTSQPGMYNMSTGMTQMLQHPNQ 882
Q+ PG +AT+ + AP S P SQP + S P
Sbjct: 2317 QQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS---------PRI 2367
Query: 883 SGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQAL 935
H+ + P G V M S Q L N + PQ+ P AL
Sbjct: 2368 QPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSAL 2420
Score = 44.3 bits (103), Expect = 7e-04
Identities = 113/515 (21%), Positives = 180/515 (34%), Gaps = 76/515 (14%)
Query: 625 MPYIQQQQQQQQQQQQQQQQQQPPPPQ------------LQAPRAHLSEDQKRLLLMKQK 672
+PY+ Q Q Q Q Q QQ QP Q + P ++ DQ+ L+ +
Sbjct: 490 LPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISES 549
Query: 673 GVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQ--- 729
+ A L + G +G T + ++ PP S G+ G L S
Sbjct: 550 ALPTSLGATNPLMNDGSNSGNIG---TLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVH 606
Query: 730 ---------PQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAE------QQL 774
P A +K ++ ++ + + E + + +LAE ++L
Sbjct: 607 KLVQAIFPTPDPAALKDRRMENLVAYAKKVEGD-MYESANSRDEYYHLLAEKIYKIQKEL 665
Query: 775 QQSHLPRQHLQPQRNPYPVQQVNQFQGS--PQDIAAVRSQAALQSMRTSRLMAQNA---- 828
++ R H Q P Q PQ VR S+ +R+
Sbjct: 666 EEKRRSRLHKQGILGNQPALPAPGAQPPVIPQ-AQPVRPPNGPLSLPVNRMQVSQGMNSF 724
Query: 829 GMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSIT 888
M +G Q P A S M + + S PG M+ ++M Q PN G
Sbjct: 725 NPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPG---MAISPSRMPQPPNMMGAHTN 781
Query: 889 HNQAQGPRQ---------PAS--GQGVGM-----VSGFGQSMLVNSAITQQHPQMKGPVG 932
+ AQ P Q P+S VGM +G Q + +A+ M GP
Sbjct: 782 NMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNP-LNMLGPQA 840
Query: 933 QALPRP---QAPPRLQSLMGTVQQGAQSWQQRSLQGM-PGRTSGELGPFNNGASYPLQAG 988
LP P Q+P + G S Q + GM P + + P +S +G
Sbjct: 841 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSS----SG 896
Query: 989 QPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQ-MMPSLPGQQGTSQARPMVMSGLS 1047
Q T P + + +T TV+ A + Q P P T Q+ + +
Sbjct: 897 Q---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVH 953
Query: 1048 QGVPGMPAFSQPPA--QQQIPSGSFAPSSQSQAYE 1080
PG P SQ A ++P+ S S+++ + +
Sbjct: 954 AQPPGTP-LSQAAASIDNRVPTPSSVASAETNSQQ 987
Score = 41.2 bits (95), Expect = 0.006
Identities = 53/252 (21%), Positives = 94/252 (37%), Gaps = 50/252 (19%)
Query: 344 PATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSG----PPFSTVSTATSLPSVAS 399
P T S + P +P + P SSSG P +V +AT S +
Sbjct: 858 PPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPT 917
Query: 400 TPAA------PNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASG 453
AA P P + +V +PQ+ Q TP A P PG L+ AA ++
Sbjct: 918 VQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP-PGTP--LSQAAASIDNRVPT 974
Query: 454 PVAVPSSDMS--------PAEQLK----------------------------QMAAQQQQ 477
P +V S++ + P ++K Q A+Q ++
Sbjct: 975 PSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKE 1034
Query: 478 RAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPM 537
+ +QK + + +++ + + + ++++ S+ S PS P F E+ +
Sbjct: 1035 ETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQAL 1094
Query: 538 MYP-QAFNNQNP 548
M +A Q+P
Sbjct: 1095 MPTLEALYRQDP 1106
Score = 33.5 bits (75), Expect = 1.2
Identities = 69/295 (23%), Positives = 97/295 (32%), Gaps = 34/295 (11%)
Query: 374 PQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPR 433
PQA+P PP +S + V+ + NP S VQ PQ P G
Sbjct: 696 PQAQPVR--PPNGPLSLPVNRMQVSQGMNSFNPMSLGN---VQLPQAPM-----GPRAAS 745
Query: 434 PGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQ- 492
P N + + +V G A P +P M AQ +++ + Q Q
Sbjct: 746 PMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGA 805
Query: 493 ------QQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQ 546
Q Q Q Q + + + LGP +S + P P P +
Sbjct: 806 MSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAG 865
Query: 547 NPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNA 606
P +LQ TT P QP+ ++S Q T G+ T +
Sbjct: 866 MP-------SLQHTTPPGMTPPQPA--APTQPSTPVSSS--GQTPTPTPGSVPSATQTQS 914
Query: 607 DLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSE 661
TP V + + P Q Q Q QQQP P Q P LS+
Sbjct: 915 ------TPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQ 963
Score = 33.1 bits (74), Expect = 1.5
Identities = 60/252 (23%), Positives = 83/252 (32%), Gaps = 37/252 (14%)
Query: 339 PEFSQPATETPLSQE-SASVKSDPSHSPFAHVS-MG-SPQARPSSSGPPFSTVSTATSLP 395
P + +P+ Q + P+ + A +S MG SP ++ SS P SLP
Sbjct: 84 PGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAP---------SLP 134
Query: 396 SVASTPAAPNPASSPA---------NCAVQSPQTP------------NQAHTPGQAPPRP 434
A++ + P PA+S A A SP T NQ H PG
Sbjct: 135 KQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTH-PGLLNSNS 193
Query: 435 GNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQ-KQQQQQQQQ 493
G+ L+N A+ A +G + A Q + L + Q Q
Sbjct: 194 GHS-LINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTG 252
Query: 494 QQQQQQQQQQQQQHSNQTSNWSPLGPP-SSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPP 552
Q T N SP G P S G A N + Q+ N P P
Sbjct: 253 HAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPT 312
Query: 553 MANNLQKTTMNN 564
N T + N
Sbjct: 313 DIKNTSVTNVPN 324
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 77.4 bits (189), Expect = 7e-14
Identities = 91/340 (26%), Positives = 146/340 (42%), Gaps = 44/340 (12%)
Query: 502 QQQQQHSNQTSNWSPLGPP-SSPYGAAFTAE--KPNSPMMYPQAFNNQ-NPIVPPMANNL 557
+ Q++ Q N SP P S+P GA+ AE +P + Q Q P P L
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQL 109
Query: 558 QKTTMNNYLPQNHMNMINQQPNNLGTNSLNK----QHNILTYGNTKP---LTHFNADLSQ 610
Q+ PQ H+ + QQP G L++ +H + + KP L H L
Sbjct: 110 QQ-------PQPHLEL-QQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQP 161
Query: 611 RMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQL-QAPRAHLSEDQKRLLLM 669
+ + QQ Q+QQ QQQ+Q QQQ QL Q + L + Q LL
Sbjct: 162 QQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQ---LLQ 218
Query: 670 KQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQ 729
+Q+ + Q + Q+Q + L + G +Q + + L Q
Sbjct: 219 QQEQLQQQQ--FQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQ-------LLEQ 269
Query: 730 PQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQ------QILAEQQLQQSHLP--- 780
QA + +Q+L+ Q+ QL +QQ+QQ L++Q++Q QQQQ + E++++ +P
Sbjct: 270 QQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDL 329
Query: 781 --RQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSM 818
Q L+ QR QQ + Q + + ++ Q LQ +
Sbjct: 330 GSEQELEQQRQELERQQELERQQEQRQL-QLKLQEELQQL 368
Score = 64.7 bits (156), Expect = 5e-10
Identities = 71/290 (24%), Positives = 115/290 (39%), Gaps = 32/290 (11%)
Query: 466 EQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYG 525
EQL+ AQ+QQ + +Q QQQ Q+QQ QQQQ+Q QQQQ Q
Sbjct: 175 EQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQ------------ 222
Query: 526 AAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNS 585
++ Q Q ++ LQ+ + Q ++ QQ L
Sbjct: 223 ----LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQL 278
Query: 586 LNKQHNILTYGNTKPLTHFNAD--LSQRMTPPVANPNKN-----PLMPY-----IQQQQQ 633
L +Q L + L + Q++ PP P + LMP + +QQ
Sbjct: 279 LLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQ 338
Query: 634 QQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSH-GQEQH 692
+Q+ ++QQ+ ++Q QLQ + ++ L +Q+ + Q + P G +Q
Sbjct: 339 RQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQ 398
Query: 693 PVGLPRT--TGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLI 740
V L T +Q + P +GG A P P + P ++ Q L+
Sbjct: 399 EVQLELTPVQPELQLELVPAAGG-GGAAVPGAPAAVVVAPPGYVVVQELM 447
Score = 57.8 bits (138), Expect = 6e-08
Identities = 105/437 (24%), Positives = 157/437 (35%), Gaps = 76/437 (17%)
Query: 629 QQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHG 688
Q++ Q QQ +QQ + QQQP QLQ P+ HL Q+ +Q G Q ++ H
Sbjct: 86 QRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQP----QQDG--QQQLSQLQQEKHQ 139
Query: 689 QEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIE 748
H +P+ +M Q Q Q+ E
Sbjct: 140 SVHHQE---------------------------------LKPELQLMHQQQQLQPQQVQE 166
Query: 749 QQKQQFLREQ--RQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDI 806
QQ+ Q +EQ QQ Q+QQ + ++QLQQ +Q LQ Q+ QQ+ Q Q Q
Sbjct: 167 QQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQ 226
Query: 807 AAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGM 866
+ Q LQ + L+ Q + + AQ + L Q +
Sbjct: 227 QFQQQQEQLQQQQQLLLLQQQGQL-------QQQLLQQQQAQLQQQLLEQQQAQLQQQLL 279
Query: 867 YNMSTGMTQMLQHP--NQSGMSITHNQAQ-GPRQPASGQGVGMVSGFGQSMLVNSAITQQ 923
+ Q Q Q + Q Q P +P + V + + M V+ Q+
Sbjct: 280 LQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVEL-----ELMPVDLGSEQE 334
Query: 924 HPQMKGPV--GQALPRPQAPPRLQ-SLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNG 980
Q + + Q L R Q +LQ L +QQ Q +Q+ Q EL P G
Sbjct: 335 LEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELG 394
Query: 981 A-----SYPLQAGQPRLTKQHFP---------QGLSQSVVDANTGTV---RTLNPAAMGR 1023
A L QP L + P G +VV A G V + A+
Sbjct: 395 AQQQEVQLELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAA 454
Query: 1024 QMMPSLPGQQGTSQARP 1040
+ ++PG G++ P
Sbjct: 455 PAVVAIPGPAGSAALTP 471
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 77.0 bits (188), Expect = 9e-14
Identities = 131/584 (22%), Positives = 199/584 (34%), Gaps = 63/584 (10%)
Query: 163 RKLEGARSPLNGDQ--QNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQ 220
R+ G+ S L + Q + DG SP ++ IR S+G + PSA+
Sbjct: 21 RRSRGSMSTLRSGRKKQPASPDGRTSPINEDIR---SSGRNS----------PSAASTSS 67
Query: 221 LDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLD 280
D K +++ L N R E SD E++ SK K + +
Sbjct: 68 NDSKAETVKKSAKKVKEEASSPLKSNKRQRE-----KVASDTEEADRT-SSKKTKTQEIS 121
Query: 281 DPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPE 340
P E S+ + + + + ++ + + ++P + ++ +++ +
Sbjct: 122 RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 181
Query: 341 FSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVAST 400
PA + P V PS +P + +P PS++ P TA+ P+
Sbjct: 182 AQPPALQAP-----TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 236
Query: 401 PAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSS 460
P AP P + PQ P H P P P L P + GSA P A PS
Sbjct: 237 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP----LQP----LTGSAGQPSA-PSH 287
Query: 461 DMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLG-P 519
P Q L+Q Q Q Q Q +PLG
Sbjct: 288 AQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ-------------APLGTS 334
Query: 520 PSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVP-PMANNLQKTTMNNYLPQNHMNMINQQP 578
P++ Y + + Q + P+ P P+A K +PQ ++ P
Sbjct: 335 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 394
Query: 579 NNL-GTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQ 637
+L G + + N+ KPL+ + PP A+P LMP Q Q
Sbjct: 395 PHLSGPSPFSMNANLPPPPALKPLSSLSTH-----HPPSAHPPPLQLMPQSQPLPSSPAQ 449
Query: 638 QQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLP 697
Q Q PPP P L + + Q P P P
Sbjct: 450 PPGLTQSQNLPPPPASHPPTGLHQ------VAPQPPFAQHPFVPGGPPPITPPTCPSTST 503
Query: 698 RTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLID 741
GP S+ PP SG SG S AG G P I ++ L D
Sbjct: 504 PPAGPGTSAQPPCSGAAASGGSIAG-GSSCPLPTVQIKEEALDD 546
Score = 36.6 bits (83), Expect = 0.14
Identities = 86/441 (19%), Positives = 144/441 (32%), Gaps = 75/441 (17%)
Query: 688 GQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLI 747
G+++ P T P+ + S AS + + + K + ++ + +
Sbjct: 33 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK--VKEEASSPL 90
Query: 748 EQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGS-PQDI 806
+ K+Q + ++ + + + Q+ P + + + VN S P+DI
Sbjct: 91 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI 150
Query: 807 AAVR--SQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQP 864
+ ++ S + + + ++ + +Q P A AP T P
Sbjct: 151 DQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTP 210
Query: 865 GMYNMSTGMTQMLQHPNQSGMSITH--NQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQ 922
G +T + P Q + + NQ Q P P +
Sbjct: 211 GPTPSATAV------PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL------------ 252
Query: 923 QHPQMKGPVGQALPRPQAPPRLQSLMGTV-QQGAQSWQQRSL--QGMPGRTSGELGPFNN 979
HPQ + P P P P LQ L G+ Q A S Q L QG PG S + GP
Sbjct: 253 -HPQ-RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 310
Query: 980 GASYPLQAGQPRLTKQ-HFPQGLSQSVVDANTGTVRTLNPAAMGRQM------------- 1025
P G P Q P G S + +T + +A+ Q
Sbjct: 311 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA 370
Query: 1026 -----------MPSLPGQQGTSQARPMVMSG-----LSQGVPGMPAF------------- 1056
+P LP Q + P +SG ++ +P PA
Sbjct: 371 MPHIKPPPTTPIPQLPAPQ--AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428
Query: 1057 SQPPAQQQIPSGSFAPSSQSQ 1077
+ PP Q +P PSS +Q
Sbjct: 429 AHPPPLQLMPQSQPLPSSPAQ 449
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 77.0 bits (188), Expect = 9e-14
Identities = 131/584 (22%), Positives = 199/584 (34%), Gaps = 63/584 (10%)
Query: 163 RKLEGARSPLNGDQ--QNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQ 220
R+ G+ S L + Q + DG SP ++ IR S+G + PSA+
Sbjct: 575 RRSRGSMSTLRSGRKKQPASPDGRTSPINEDIR---SSGRNS----------PSAASTSS 621
Query: 221 LDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLD 280
D K +++ L N R E SD E++ SK K + +
Sbjct: 622 NDSKAETVKKSAKKVKEEASSPLKSNKRQRE-----KVASDTEEADRT-SSKKTKTQEIS 675
Query: 281 DPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPE 340
P E S+ + + + + ++ + + ++P + ++ +++ +
Sbjct: 676 RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 735
Query: 341 FSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVAST 400
PA + P V PS +P + +P PS++ P TA+ P+
Sbjct: 736 AQPPALQAP-----TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790
Query: 401 PAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSS 460
P AP P + PQ P H P P P L P + GSA P A PS
Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP----LQP----LTGSAGQPSA-PSH 841
Query: 461 DMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLG-P 519
P Q L+Q Q Q Q Q +PLG
Sbjct: 842 AQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ-------------APLGTS 888
Query: 520 PSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVP-PMANNLQKTTMNNYLPQNHMNMINQQP 578
P++ Y + + Q + P+ P P+A K +PQ ++ P
Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948
Query: 579 NNL-GTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQ 637
+L G + + N+ KPL+ + PP A+P LMP Q Q
Sbjct: 949 PHLSGPSPFSMNANLPPPPALKPLSSLSTH-----HPPSAHPPPLQLMPQSQPLPSSPAQ 1003
Query: 638 QQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLP 697
Q Q PPP P L + + Q P P P
Sbjct: 1004 PPGLTQSQNLPPPPASHPPTGLHQ------VAPQPPFAQHPFVPGGPPPITPPTCPSTST 1057
Query: 698 RTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLID 741
GP S+ PP SG SG S AG G P I ++ L D
Sbjct: 1058 PPAGPGTSAQPPCSGAAASGGSIAG-GSSCPLPTVQIKEEALDD 1100
Score = 36.6 bits (83), Expect = 0.14
Identities = 86/441 (19%), Positives = 144/441 (32%), Gaps = 75/441 (17%)
Query: 688 GQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLI 747
G+++ P T P+ + S AS + + + K + ++ + +
Sbjct: 587 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK--VKEEASSPL 644
Query: 748 EQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGS-PQDI 806
+ K+Q + ++ + + + Q+ P + + + VN S P+DI
Sbjct: 645 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI 704
Query: 807 AAVR--SQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQP 864
+ ++ S + + + ++ + +Q P A AP T P
Sbjct: 705 DQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTP 764
Query: 865 GMYNMSTGMTQMLQHPNQSGMSITH--NQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQ 922
G +T + P Q + + NQ Q P P +
Sbjct: 765 GPTPSATAV------PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL------------ 806
Query: 923 QHPQMKGPVGQALPRPQAPPRLQSLMGTV-QQGAQSWQQRSL--QGMPGRTSGELGPFNN 979
HPQ + P P P P LQ L G+ Q A S Q L QG PG S + GP
Sbjct: 807 -HPQ-RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864
Query: 980 GASYPLQAGQPRLTKQ-HFPQGLSQSVVDANTGTVRTLNPAAMGRQM------------- 1025
P G P Q P G S + +T + +A+ Q
Sbjct: 865 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA 924
Query: 1026 -----------MPSLPGQQGTSQARPMVMSG-----LSQGVPGMPAF------------- 1056
+P LP Q + P +SG ++ +P PA
Sbjct: 925 MPHIKPPPTTPIPQLPAPQ--AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 1057 SQPPAQQQIPSGSFAPSSQSQ 1077
+ PP Q +P PSS +Q
Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQ 1003
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 77.0 bits (188), Expect = 9e-14
Identities = 131/584 (22%), Positives = 199/584 (34%), Gaps = 63/584 (10%)
Query: 163 RKLEGARSPLNGDQ--QNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQ 220
R+ G+ S L + Q + DG SP ++ IR S+G + PSA+
Sbjct: 575 RRSRGSMSTLRSGRKKQPASPDGRTSPINEDIR---SSGRNS----------PSAASTSS 621
Query: 221 LDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLD 280
D K +++ L N R E SD E++ SK K + +
Sbjct: 622 NDSKAETVKKSAKKVKEEASSPLKSNKRQRE-----KVASDTEEADRT-SSKKTKTQEIS 675
Query: 281 DPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPE 340
P E S+ + + + + ++ + + ++P + ++ +++ +
Sbjct: 676 RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 735
Query: 341 FSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVAST 400
PA + P V PS +P + +P PS++ P TA+ P+
Sbjct: 736 AQPPALQAP-----TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790
Query: 401 PAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSS 460
P AP P + PQ P H P P P L P + GSA P A PS
Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP----LQP----LTGSAGQPSA-PSH 841
Query: 461 DMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLG-P 519
P Q L+Q Q Q Q Q +PLG
Sbjct: 842 AQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ-------------APLGTS 888
Query: 520 PSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVP-PMANNLQKTTMNNYLPQNHMNMINQQP 578
P++ Y + + Q + P+ P P+A K +PQ ++ P
Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP 948
Query: 579 NNL-GTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQ 637
+L G + + N+ KPL+ + PP A+P LMP Q Q
Sbjct: 949 PHLSGPSPFSMNANLPPPPALKPLSSLSTH-----HPPSAHPPPLQLMPQSQPLPSSPAQ 1003
Query: 638 QQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLP 697
Q Q PPP P L + + Q P P P
Sbjct: 1004 PPGLTQSQNLPPPPASHPPTGLHQ------VAPQPPFAQHPFVPGGPPPITPPTCPSTST 1057
Query: 698 RTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLID 741
GP S+ PP SG SG S AG G P I ++ L D
Sbjct: 1058 PPAGPGTSAQPPCSGAAASGGSIAG-GSSCPLPTVQIKEEALDD 1100
Score = 36.6 bits (83), Expect = 0.14
Identities = 86/441 (19%), Positives = 144/441 (32%), Gaps = 75/441 (17%)
Query: 688 GQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLI 747
G+++ P T P+ + S AS + + + K + ++ + +
Sbjct: 587 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK--VKEEASSPL 644
Query: 748 EQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGS-PQDI 806
+ K+Q + ++ + + + Q+ P + + + VN S P+DI
Sbjct: 645 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI 704
Query: 807 AAVR--SQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQP 864
+ ++ S + + + ++ + +Q P A AP T P
Sbjct: 705 DQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTP 764
Query: 865 GMYNMSTGMTQMLQHPNQSGMSITH--NQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQ 922
G +T + P Q + + NQ Q P P +
Sbjct: 765 GPTPSATAV------PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL------------ 806
Query: 923 QHPQMKGPVGQALPRPQAPPRLQSLMGTV-QQGAQSWQQRSL--QGMPGRTSGELGPFNN 979
HPQ + P P P P LQ L G+ Q A S Q L QG PG S + GP
Sbjct: 807 -HPQ-RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864
Query: 980 GASYPLQAGQPRLTKQ-HFPQGLSQSVVDANTGTVRTLNPAAMGRQM------------- 1025
P G P Q P G S + +T + +A+ Q
Sbjct: 865 HPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLA 924
Query: 1026 -----------MPSLPGQQGTSQARPMVMSG-----LSQGVPGMPAF------------- 1056
+P LP Q + P +SG ++ +P PA
Sbjct: 925 MPHIKPPPTTPIPQLPAPQ--AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 1057 SQPPAQQQIPSGSFAPSSQSQ 1077
+ PP Q +P PSS +Q
Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQ 1003
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 74.7 bits (182), Expect = 5e-13
Identities = 169/678 (24%), Positives = 223/678 (32%), Gaps = 159/678 (23%)
Query: 482 MQQKQQQQQQQ---QQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMM 538
++QK +QQQ Q QQ Q +++ Q + L P+ T ++P +P
Sbjct: 1809 IKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQT 1868
Query: 539 YPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNT 598
PQ + P P +M YLP+ G S K G
Sbjct: 1869 -PQPTSQPQPTPP--------NSMPPYLPRTQA---------AGPVSQGK-----AAGQV 1905
Query: 599 KPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQ--------QQQQP--- 647
P T Q PP+ P + +Q Q+ + Q+Q Q Q P
Sbjct: 1906 TPPTP-----PQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMT 1960
Query: 648 --------PPPQLQAPRAHLSEDQKRLLLMKQKGVMNQ-PMAYAALPSHGQEQHPVGLPR 698
PPP + P HL M G+ Q P + LP Q Q G+PR
Sbjct: 1961 PMAPMGMNPPPMTRGPSGHLEPG------MGPTGMQQQPPWSQGGLPQPQQLQS--GMPR 2012
Query: 699 TT--------GPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQ 750
P+ + PG G + G SP PG + +Q
Sbjct: 2013 PAMMSVAQHGQPLNMAPQPGLGQV--GISPLKPGTVS--------------------QQA 2050
Query: 751 KQQFLREQRQQQQ--QQQQIL----AEQQLQQSHLPRQHLQ-PQRNPYPVQ-QVNQFQGS 802
Q LR R QQQQ+L A QL + + ++ + NP P+ Q QG
Sbjct: 2051 LQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQ 2110
Query: 803 P-------QDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQN----PGTMATAAAQSEM 851
P V S A+Q+M + Q AG+ P Q G M+ A Q M
Sbjct: 2111 PGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNM 2170
Query: 852 GLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMS-------ITHNQAQGPRQPASGQGV 904
+ P + QM+Q Q G HNQ Q P QGV
Sbjct: 2171 -------NHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQP------QGV 2217
Query: 905 GMVSGFGQSMLVNSAITQQHPQ--MKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRS 962
G Q M Q H Q +G +GQ PQA L Q++QQR
Sbjct: 2218 GYPPQQQQRM-------QHHMQQMQQGNMGQIGQLPQA------LGAEAGASLQAYQQRL 2264
Query: 963 LQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMG 1022
LQ G P QA P L Q P LS VR+ P
Sbjct: 2265 LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQ--------VRSPQPVPSP 2316
Query: 1023 R-QMMP--SLPGQQGTSQARP-MVMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQA 1078
R Q P S P + Q P V S PG+ A P +Q G FA Q+
Sbjct: 2317 RPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQ----GHFASPDQNSM 2372
Query: 1079 YERNAPQDVSYNYSGDGA 1096
+ A N G A
Sbjct: 2373 LSQLASNPGMANLHGASA 2390
Score = 65.9 bits (159), Expect = 2e-10
Identities = 147/619 (23%), Positives = 205/619 (33%), Gaps = 96/619 (15%)
Query: 388 VSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHT--PGQAPPRPGNGYLLNPAAV 445
V LPS TPA P + Q+PQ +Q P PP P +
Sbjct: 1841 VGQQQGLPS--PTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVS- 1897
Query: 446 TVAGSASGPVAVPSSDMS-------PAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQ 498
G A+G V P+ + P +MA Q Q+ A+ Q+Q Q Q+ Q
Sbjct: 1898 --QGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAE--TQRQMAHVQIFQRPIQ 1953
Query: 499 QQQQQQQQHSNQTSNWSP--------LGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIV 550
Q + N P L P P G + PQ + P
Sbjct: 1954 HQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMP-R 2012
Query: 551 PPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQ 610
P M + Q N PQ + + P GT S N+L + L ++ L Q
Sbjct: 2013 PAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLL-----RTLRSPSSPLQQ 2067
Query: 611 RMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQ----LQAPRAHLSEDQKRL 666
+ + + N L +I+Q+ + Q QP PQ LQ P
Sbjct: 2068 QQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPP----------- 2116
Query: 667 LLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFL 726
+ Q+GV + P P Q GLP+ P Q PP GGM
Sbjct: 2117 TMPGQQGVHSNPAMQNMNPMQAGVQR-AGLPQQQ-PQQQLQPP-MGGM------------ 2161
Query: 727 GSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQP 786
PQA M + + Q + LR Q+ QQQQQQ Q QP
Sbjct: 2162 --SPQAQQM-----NMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQP 2214
Query: 787 QRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAA 846
Q YP QQ + Q Q ++ N G +G P Q G A A+
Sbjct: 2215 QGVGYPPQQQQRMQHHMQ-----------------QMQQGNMGQIGQLP-QALGAEAGAS 2256
Query: 847 AQS--EMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITH---NQAQGPRQPASG 901
Q+ + L +P M + Q P+ G I + NQ + P+ S
Sbjct: 2257 LQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSP 2316
Query: 902 QGVGMVSGFGQSMLVNSAITQQH--PQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQ 959
+ S + + H PQ P L QA P Q + Q + Q
Sbjct: 2317 RPQSQPPHSSPSPRMQPQPSPHHVSPQTSSP-HPGLVAAQANPMEQGHFASPDQNSMLSQ 2375
Query: 960 QRSLQGMP---GRTSGELG 975
S GM G ++ +LG
Sbjct: 2376 LASNPGMANLHGASATDLG 2394
Score = 53.9 bits (128), Expect = 8e-07
Identities = 79/292 (27%), Positives = 119/292 (40%), Gaps = 37/292 (12%)
Query: 796 VNQFQ---GSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMG 852
+NQ Q G QD A+ Q + + +R+ N G+ G G MA+ A QS G
Sbjct: 61 INQLQTSLGMVQDAASKHKQLS-ELLRSGSSPNLNMGVGGPGQ-----VMASQAQQSSPG 114
Query: 853 LAPYST---TPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSG 909
L ++ +P +Q G+ + + GM PNQ T QPA G GM +G
Sbjct: 115 LGLINSMVKSPMTQAGLTSPNMGMGT--SGPNQGPTQSTGMMNSPVNQPAMGMNTGMNAG 172
Query: 910 FGQSMLV--NSAITQQHPQMKGPVG-------QALPRPQAPPRLQSLMGTVQQGAQSWQQ 960
ML N + M G +G P P L +QQG S Q
Sbjct: 173 MNPGMLAAGNGQGIMPNQVMNGSIGAGRGRQNMQYPNPGMGSAGNLLTEPLQQG--SPQM 230
Query: 961 RSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTV--RTLNP 1018
G+ G ++G NN Y G P G S + T TV L+P
Sbjct: 231 GGQTGLRGPQPLKMGMMNNPNPY----GSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSP 286
Query: 1019 AAMGRQMMP--SLP--GQQGTSQA-RPMVMSGLSQGVPGMPAFSQPPAQQQI 1065
AM ++ +P +P GQQ Q +P +++ ++QG+ G A + P ++++
Sbjct: 287 FAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGM-GSGAHTADPEKRKL 337
Score = 46.2 bits (108), Expect = 2e-04
Identities = 143/756 (18%), Positives = 244/756 (32%), Gaps = 90/756 (11%)
Query: 414 AVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAA 473
AV PN P +PG L+ P A G SG A+ K+
Sbjct: 293 AVPGGGMPNMGQQPAPQVQQPG---LVTPVA---QGMGSGA--------HTADPEKRKLI 338
Query: 474 QQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKP 533
QQQ L K Q+++Q + +Q + N ++ + S A A
Sbjct: 339 QQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQ-VAHCASSR 397
Query: 534 NSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNIL 593
+ + P+ P+ N K L + + N P++LG + N+
Sbjct: 398 QIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPVGLGN--PSSLGVGQQSAP-NLS 454
Query: 594 TYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQ 653
T P + A + + V N+ P P +Q + QQ QQ Q Q +P
Sbjct: 455 TVSQIDPSSIERAYAALGLPYQV---NQMPTQPQVQAKNQQNQQPGQSPQGMRPMSNMSA 511
Query: 654 APRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGG 713
+P + ++ +++ M ++A+ S + GPM ++ P + G
Sbjct: 512 SPMGVNGG-----VGVQTPSLLSDSMLHSAINSQNPMMSENASVPSLGPMPTAAQPSTTG 566
Query: 714 --------------------MVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQ 753
+V P P A +K ++ + +
Sbjct: 567 IRKQWHEDITQDLRNHLVHKLVQAIFPT--------PDPAALKDRRMENLVAYARKVEGD 618
Query: 754 FLREQRQQQQQQQQILAE---------QQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQ 804
+ E + + +LAE ++ +++ L +Q++ P +N Q
Sbjct: 619 -MYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQ 677
Query: 805 DIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPT--- 861
+ S L R N M I P + ++ + P T P
Sbjct: 678 PQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMS-MAQPPIVPRQTPPLQHH 736
Query: 862 ---SQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNS 918
+QPG N G +Q P+ G + Q Q P Q + + + GQ+ + +
Sbjct: 737 GQLAQPGALNPPMGYGPRMQQPSNQGQFLP--QTQFPSQGMNVTNIPLAPSSGQAPVSQA 794
Query: 919 AITQQHPQMKGPVGQALPRPQAPPRLQ-SLMGTVQQGAQSWQQRSLQGMPGRT-SGELGP 976
++ + P+ PP Q S + Q + Q S +P RT + P
Sbjct: 795 QMSSSSCPVNSPI--------MPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTP 846
Query: 977 FNNGASYP--LQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQG 1034
+ GA P P T P G + T + +Q+ PSLP
Sbjct: 847 PSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPS 906
Query: 1035 TS--QARPMVMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYERNAPQDVSYNYS 1092
Q +P + VP A PP Q P A S + Q N P S +
Sbjct: 907 ADQPQQQPRSQQSTAASVPTPTAPLLPP-QPATPLSQPAVSIEGQV--SNPPSTSSTEVN 963
Query: 1093 GDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDE 1128
P + + + P D +++ E
Sbjct: 964 SQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISE 999
Score = 41.2 bits (95), Expect = 0.006
Identities = 56/225 (24%), Positives = 80/225 (35%), Gaps = 21/225 (9%)
Query: 339 PEFSQPATETPLSQESA--SVKSDPSHSPFAHVSMGSP--QARPSSSGPPF-STVSTATS 393
P QP+ + ++ S + ++ P A S +P QA+ SSS P S + S
Sbjct: 753 PRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGS 812
Query: 394 LPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASG 453
S P P PA + + +TP HTP P G P A T+
Sbjct: 813 QGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTP------PSIG-AQQPPATTIPAPVPT 865
Query: 454 PVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSN 513
P A+P S A +L QQ Q Q QQQ + QQ S S
Sbjct: 866 PPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQ-STAASV 924
Query: 514 WSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQ 558
+P P P +P +P+ P PP ++ +
Sbjct: 925 PTPTAPLLPP--------QPATPLSQPAVSIEGQVSNPPSTSSTE 961
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 72.8 bits (177), Expect = 2e-12
Identities = 87/283 (30%), Positives = 112/283 (39%), Gaps = 67/283 (23%)
Query: 466 EQLKQMAAQQQQRAKLMQQKQQQQQQQQQ----------QQQQQQQQQQQQHSNQTSNWS 515
+QL+Q QQQ KL Q QQQ QQQQQ QQQQQQQQQQQQ Q
Sbjct: 208 QQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267
Query: 516 PLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMIN 575
P P P PM PQ +Q +P + T + PQ +
Sbjct: 268 P--PIQQP------------PMQQPQPPPSQ--ALPQQLQQMHHTQHHQPPPQPQQPPVA 311
Query: 576 Q-QPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRM--TPPVANPNKNPLMPYIQQQQ 632
Q QP+ L S T+PL L +M T P + P++ +QQ
Sbjct: 312 QNQPSQLPPQS-----------QTQPLVSQAQALPGQMLYTQPPLKFVRAPMV--VQQPP 358
Query: 633 QQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQE-Q 691
Q Q QQQQ Q Q+ AP +S+ +L + PS GQ+ Q
Sbjct: 359 VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPML---------------SSPSPGQQVQ 403
Query: 692 HPVGLPRTTGPMQSSVPPG------SGGMVSGASPAGPGFLGS 728
P +P P Q S PG + + SG +P+ FL S
Sbjct: 404 TPQSMP---PPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 443
Score = 72.4 bits (176), Expect = 2e-12
Identities = 107/417 (25%), Positives = 143/417 (34%), Gaps = 105/417 (25%)
Query: 411 ANCAVQSPQTPNQAHTPGQA--------PPR-PGN--GYLLNPAAVTVAGSASGPVAVPS 459
+ +V P Q+ T G A PPR PG G + + A+ S SG +
Sbjct: 74 SQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGT 133
Query: 460 SDMSPAE-------------QLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQ 506
S M+P QL+Q+A QQQQ+ + QQ+QQ QQQQQQQQQQQ Q QQ
Sbjct: 134 SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQ 193
Query: 507 HSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYL 566
+ Q F A + Q Q+ I N Q L
Sbjct: 194 SAMQQQ---------------FQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL 238
Query: 567 PQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMP 626
+ + QQ +Q + + PP+ P P
Sbjct: 239 QRIAQLQLQQQQQQQQQQQQQQQQAL------------------QAQPPIQQPPMQQPQP 280
Query: 627 YIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPS 686
Q QQ QQ Q QPPP Q P A NQP + LP
Sbjct: 281 PPSQALPQQLQQMHHTQHHQPPPQPQQPPVA-----------------QNQP---SQLPP 320
Query: 687 HGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQL 746
Q Q V Q+ PG L +QP ++ ++ Q+ +
Sbjct: 321 QSQTQPLVS--------QAQALPGQ-------------MLYTQPPLKFVRAPMVVQQPPV 359
Query: 747 IEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSP 803
Q +QQ + Q Q Q + Q+ QS LP +P P QQV Q P
Sbjct: 360 QPQVQQQ--QTAVQTAQAAQMVAPGVQVSQSSLPM-----LSSPSPGQQVQTPQSMP 409
Score = 66.6 bits (161), Expect = 1e-10
Identities = 74/282 (26%), Positives = 102/282 (36%), Gaps = 48/282 (17%)
Query: 466 EQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYG 525
+Q Q QQ QR +Q +QQQQQQQQQQQQQQQ Q Q Q P PPS
Sbjct: 228 QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287
Query: 526 AAFTA-------EKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHM------- 571
+ P P P A NQ +PP + + LP +
Sbjct: 288 QQLQQMHHTQHHQPPPQPQQPPVA-QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLK 346
Query: 572 ----NMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPY 627
M+ QQP + +Q + + +SQ P +++P+
Sbjct: 347 FVRAPMVVQQPP--VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPG----- 399
Query: 628 IQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSH 687
QQ Q Q PPPPQ P + + G P ++ PS
Sbjct: 400 ----------QQVQTPQSMPPPPQ---PSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSP 446
Query: 688 GQEQHPV--------GLPRTTGPMQSSVPPGSGGMVSGASPA 721
Q PV +P + GP+ + V P S +G+S A
Sbjct: 447 QPSQSPVTARTPQNFSVP-SPGPLNTPVNPSSVMSPAGSSQA 487
Score = 57.0 bits (136), Expect = 1e-07
Identities = 110/432 (25%), Positives = 149/432 (34%), Gaps = 73/432 (16%)
Query: 669 MKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGP----- 723
M G M QPM+ + P G S + P S +VS A+P
Sbjct: 113 MGSLGAMGQPMSLSGQPPPGT---------------SGMAPHSMAVVSTATPQTQLQLQQ 157
Query: 724 -GFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQ------QQQQILAEQQLQQ 776
Q Q +Q + Q +QQ+QQF +Q QQ QQQQ L +QQ QQ
Sbjct: 158 VALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQ 217
Query: 777 SHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPS 836
HL + H Q Q QQ+ Q Q Q IA ++ Q Q + + Q A + P
Sbjct: 218 QHLIKLHHQNQ------QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQA-LQAQPPI 270
Query: 837 QNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGM-SITHNQ-AQG 894
Q P + P P M++ TQ Q P Q + NQ +Q
Sbjct: 271 QQP-------PMQQPQPPPSQALPQQLQQMHH-----TQHHQPPPQPQQPPVAQNQPSQL 318
Query: 895 PRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQG 954
P Q + V ML Q P + +P P++Q QQ
Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYT-----QPPLKFVRAPMVVQQPPVQPQVQQ-----QQT 368
Query: 955 AQSWQQRSLQGMPG-RTSGELGPFNNGASYPLQAGQPRL---TKQHFPQ-GLSQSVVDAN 1009
A Q + PG + S P + S Q P+ Q PQ G S ++N
Sbjct: 369 AVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSN 428
Query: 1010 TGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQQIPSGS 1069
+ PA +PS Q S S PG P PS
Sbjct: 429 VSS----GPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPG------PLNTPVNPSSV 478
Query: 1070 FAPSSQSQAYER 1081
+P+ SQA E+
Sbjct: 479 MSPAGSSQAEEQ 490
Score = 38.9 bits (89), Expect = 0.028
Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 6/145 (4%)
Query: 343 QPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGP-PFSTVSTATSLPSVASTP 401
QP + + Q+ +V++ + A S + P S P P V T S+P
Sbjct: 356 QPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPS 415
Query: 402 AAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVP--- 458
P SS N V S P+ + P+P + + + GP+ P
Sbjct: 416 PQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNP 475
Query: 459 SSDMSPAEQLKQMAAQQQQRAKLMQ 483
SS MSPA A +QQ KL Q
Sbjct: 476 SSVMSPAG--SSQAEEQQYLDKLKQ 498
Score = 30.8 bits (68), Expect = 7.6
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 6/99 (6%)
Query: 339 PEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVA 398
P S P+ + Q S+ P SP G P ++P+S+ S ++ LPS +
Sbjct: 391 PMLSSPSPGQQV-QTPQSMPPPPQPSP----QPGQPSSQPNSNVSSGPAPSPSSFLPSPS 445
Query: 399 STPA-APNPASSPANCAVQSPQTPNQAHTPGQAPPRPGN 436
P+ +P A +P N +V SP N P G+
Sbjct: 446 PQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 484
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 72.4 bits (176), Expect = 2e-12
Identities = 128/579 (22%), Positives = 205/579 (35%), Gaps = 81/579 (13%)
Query: 176 QQNGACDGNFSPT-SKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGT 234
Q + + DG + T +K+I+ + M + + N P + K + +QNSGT
Sbjct: 907 QTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFS----STKSMMSVQNSGT 962
Query: 235 HTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSN 294
G NG + LQS + Q+ S+ L +
Sbjct: 963 QQQG------------------NGLFQQGNEMMSLQSGNFLQQS-------SHSQAQLFH 997
Query: 295 QNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQES 354
+D QE Q + N + +E + P F +T L S
Sbjct: 998 PQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQP---PMFHSQSTIAVLQGSS 1054
Query: 355 ASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCA 414
++ + M + Q + F+ + S+ + ST + A+
Sbjct: 1055 VPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPN---SISPLQSTSNSEQQAAFQQQAP 1111
Query: 415 VQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQ 474
+ QTP + Q PP+ G L P VA+ S +P Q +Q
Sbjct: 1112 ISHIQTPMLSQEQAQ-PPQQG---LFQPQ-----------VALGSLPPNPMPQSQQGTMF 1156
Query: 475 QQQRAKL-MQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKP 533
Q Q + + MQ Q+QQQQQQQQQQQQQQQQ S SN + + +SP ++P
Sbjct: 1157 QSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASP-------KQP 1209
Query: 534 NSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNIL 593
M++ NP PMAN Q+ + + Q++M +NQ+ + S + ++
Sbjct: 1210 PPNMIF-------NPNQNPMANQEQQ-NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1261
Query: 594 TYGNTK------PLTHFNADLSQRMTPPVANPNKNPL------MPYIQQQQQQQQQQQQQ 641
G T+ PL H + + P + + L M +Q QQ QQ
Sbjct: 1262 NPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSP 1321
Query: 642 QQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTG 701
Q P +Q + + Q L G MNQ G+
Sbjct: 1322 LYSPQNNMPGIQGATSS-PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1380
Query: 702 PMQSSVPPGSGGMVSGAS-PAGPGFLGSQPQAAIMKQML 739
+ +S P + S P P G P ++ Q +
Sbjct: 1381 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQM 1419
Score = 60.8 bits (146), Expect = 7e-09
Identities = 166/817 (20%), Positives = 280/817 (34%), Gaps = 192/817 (23%)
Query: 288 SETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPAT- 346
SE +LSNQ + Q+ Q++++ A V E +Q + + + F A+
Sbjct: 796 SENTLSNQQQ-------QQQQQQQVMESSAAMVME--MQQSICQAAAQIQSELFPSTASA 846
Query: 347 -----ETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTP 401
++P+ Q+++ + S S + + + P+ SG ST +T + + +T
Sbjct: 847 NGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQ-QVATPGTTM 905
Query: 402 AAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSD 461
+ + Q+ Q N G+ N V + S ++V +S
Sbjct: 906 FQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGD----NQPQVNLFSSTKSMMSVQNS- 960
Query: 462 MSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPS 521
QQQ Q + Q QQ Q Q Q
Sbjct: 961 ----------GTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQ 1010
Query: 522 SPYGAAFTAEKP---------NSPMMYPQAFNNQNPIVPPMANNL--QKTTMNNYLPQNH 570
G+ F + P +S M P F++Q+ I +++ + + N +L Q+
Sbjct: 1011 ETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSP 1070
Query: 571 MNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQ 630
MN NL TN++ ++ + PL
Sbjct: 1071 MN-------NLQTNTVAQEAFFAAPNSISPL----------------------------- 1094
Query: 631 QQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQE 690
Q +QQ QQQ P +Q P LS++Q + Q+G+ +A +LP +
Sbjct: 1095 -QSTSNSEQQAAFQQQAPISHIQTPM--LSQEQAQ---PPQQGLFQPQVALGSLPPNPMP 1148
Query: 691 QHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQ 750
Q G T Q S+ + SP+ ++Q
Sbjct: 1149 QSQQG---TMFQSQHSIVA-----MQSNSPS--------------------------QEQ 1174
Query: 751 KQQFLREQRQQQQQQQQILAEQQLQQSHL-------PRQHLQPQRNPYPVQQVNQFQGSP 803
+QQ ++Q+QQQQQQQ IL Q + + P P +NP NQ Q
Sbjct: 1175 QQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP----MANQEQ--- 1227
Query: 804 QDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQ 863
Q+ + Q+ + M + Q + QNPG + ++Q+ + + ++P Q
Sbjct: 1228 QNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPL----FHSSPQIQ 1283
Query: 864 PGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQ 923
+ S+ Q+ + + MS + + Q + S +
Sbjct: 1284 LVQGSPSSQEQQVTLFLSPASMS------------------ALQTSINQQDMQQSPLYSP 1325
Query: 924 HPQMKGPVG-QALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGAS 982
M G G + P+PQA + GT+ Q LQ PG + G F G
Sbjct: 1326 QNNMPGIQGATSSPQPQATLFHNTAGGTMNQ---------LQNSPGSSQQTSGMFLFG-- 1374
Query: 983 YPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMP-SLPGQQGTSQARPM 1041
+ N + T PA + Q+M S PGQ ++ +P
Sbjct: 1375 -----------------------IQNNCSQLLTSGPATLPDQLMAISQPGQP-QNEGQPP 1410
Query: 1042 VMSGLSQGVP-GMPAFSQPPAQQQIPSGSFAPSSQSQ 1077
V + LSQ +P P S Q I S Q+Q
Sbjct: 1411 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQ 1447
Score = 52.0 bits (123), Expect = 3e-06
Identities = 101/488 (20%), Positives = 177/488 (36%), Gaps = 56/488 (11%)
Query: 457 VPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSP 516
+P++ M+P + ++ ++ +K+ + + QQ + SN N
Sbjct: 512 IPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGN--- 568
Query: 517 LGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQ 576
G SSP + +E + P+A+N P +Q ++ ++ +Q
Sbjct: 569 -GSFSSPSSSHLPSENEKQQQIQPKAYN------PETLTTIQTQDISQPGTFPAVSASSQ 621
Query: 577 QPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQ 636
PN+ ++L +Q T+ +D + N + L QQQQQ
Sbjct: 622 LPNS---DALLQQATQFQTRETQSREILQSDGTV--------VNLSQLTEASQQQQQSPL 670
Query: 637 QQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL 696
Q+Q Q QQQ +P + +S+ Q + + Q G A + S Q +
Sbjct: 671 QEQAQTLQQQISSNIFPSPNS-VSQLQNTIQQL-QAGSFTGSTASGSSGSVDLVQQVLEA 728
Query: 697 PRTTGPMQSSVPPGSGGMV---------------SGASPAGPGFLGSQPQAAIMKQMLID 741
+ + S P G+ + SG SP F ++P L+
Sbjct: 729 QQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGM--FSSTEPTVHTRPDNLLP 786
Query: 742 QRAQLIEQQKQQFLREQRQQQQQQQQILAE-----QQLQQSHL-PRQHLQPQRNPYPVQQ 795
RA+ + Q + L Q+QQQQQQQQ++ ++QQS +Q + P
Sbjct: 787 GRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASA 846
Query: 796 VNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAP 855
Q SP ++ + ++ T+ M + P+ + +T Q +A
Sbjct: 847 NGNLQQSP---VYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQ---VAT 900
Query: 856 YSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSML 915
TT + TQ Q N ++ Q G QP V + S M
Sbjct: 901 PGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQ----VNLFSSTKSMMS 956
Query: 916 VNSAITQQ 923
V ++ TQQ
Sbjct: 957 VQNSGTQQ 964
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 72.4 bits (176), Expect = 2e-12
Identities = 128/579 (22%), Positives = 205/579 (35%), Gaps = 81/579 (13%)
Query: 176 QQNGACDGNFSPT-SKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGT 234
Q + + DG + T +K+I+ + M + + N P + K + +QNSGT
Sbjct: 983 QTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFS----STKSMMSVQNSGT 1038
Query: 235 HTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSN 294
G NG + LQS + Q+ S+ L +
Sbjct: 1039 QQQG------------------NGLFQQGNEMMSLQSGNFLQQS-------SHSQAQLFH 1073
Query: 295 QNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQES 354
+D QE Q + N + +E + P F +T L S
Sbjct: 1074 PQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQP---PMFHSQSTIAVLQGSS 1130
Query: 355 ASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCA 414
++ + M + Q + F+ + S+ + ST + A+
Sbjct: 1131 VPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPN---SISPLQSTSNSEQQAAFQQQAP 1187
Query: 415 VQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQ 474
+ QTP + Q PP+ G L P VA+ S +P Q +Q
Sbjct: 1188 ISHIQTPMLSQEQAQ-PPQQG---LFQPQ-----------VALGSLPPNPMPQSQQGTMF 1232
Query: 475 QQQRAKL-MQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKP 533
Q Q + + MQ Q+QQQQQQQQQQQQQQQQ S SN + + +SP ++P
Sbjct: 1233 QSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASP-------KQP 1285
Query: 534 NSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNIL 593
M++ NP PMAN Q+ + + Q++M +NQ+ + S + ++
Sbjct: 1286 PPNMIF-------NPNQNPMANQEQQ-NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1337
Query: 594 TYGNTK------PLTHFNADLSQRMTPPVANPNKNPL------MPYIQQQQQQQQQQQQQ 641
G T+ PL H + + P + + L M +Q QQ QQ
Sbjct: 1338 NPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSP 1397
Query: 642 QQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTG 701
Q P +Q + + Q L G MNQ G+
Sbjct: 1398 LYSPQNNMPGIQGATSS-PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1456
Query: 702 PMQSSVPPGSGGMVSGAS-PAGPGFLGSQPQAAIMKQML 739
+ +S P + S P P G P ++ Q +
Sbjct: 1457 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQM 1495
Score = 60.8 bits (146), Expect = 7e-09
Identities = 166/817 (20%), Positives = 280/817 (34%), Gaps = 192/817 (23%)
Query: 288 SETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPAT- 346
SE +LSNQ + Q+ Q++++ A V E +Q + + + F A+
Sbjct: 872 SENTLSNQQQ-------QQQQQQQVMESSAAMVME--MQQSICQAAAQIQSELFPSTASA 922
Query: 347 -----ETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTP 401
++P+ Q+++ + S S + + + P+ SG ST +T + + +T
Sbjct: 923 NGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQ-QVATPGTTM 981
Query: 402 AAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSD 461
+ + Q+ Q N G+ N V + S ++V +S
Sbjct: 982 FQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGD----NQPQVNLFSSTKSMMSVQNS- 1036
Query: 462 MSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPS 521
QQQ Q + Q QQ Q Q Q
Sbjct: 1037 ----------GTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQ 1086
Query: 522 SPYGAAFTAEKP---------NSPMMYPQAFNNQNPIVPPMANNL--QKTTMNNYLPQNH 570
G+ F + P +S M P F++Q+ I +++ + + N +L Q+
Sbjct: 1087 ETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSP 1146
Query: 571 MNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQ 630
MN NL TN++ ++ + PL
Sbjct: 1147 MN-------NLQTNTVAQEAFFAAPNSISPL----------------------------- 1170
Query: 631 QQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQE 690
Q +QQ QQQ P +Q P LS++Q + Q+G+ +A +LP +
Sbjct: 1171 -QSTSNSEQQAAFQQQAPISHIQTPM--LSQEQAQ---PPQQGLFQPQVALGSLPPNPMP 1224
Query: 691 QHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQ 750
Q G T Q S+ + SP+ ++Q
Sbjct: 1225 QSQQG---TMFQSQHSIVA-----MQSNSPS--------------------------QEQ 1250
Query: 751 KQQFLREQRQQQQQQQQILAEQQLQQSHL-------PRQHLQPQRNPYPVQQVNQFQGSP 803
+QQ ++Q+QQQQQQQ IL Q + + P P +NP NQ Q
Sbjct: 1251 QQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP----MANQEQ--- 1303
Query: 804 QDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQ 863
Q+ + Q+ + M + Q + QNPG + ++Q+ + + ++P Q
Sbjct: 1304 QNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPL----FHSSPQIQ 1359
Query: 864 PGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQ 923
+ S+ Q+ + + MS + + Q + S +
Sbjct: 1360 LVQGSPSSQEQQVTLFLSPASMS------------------ALQTSINQQDMQQSPLYSP 1401
Query: 924 HPQMKGPVG-QALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGAS 982
M G G + P+PQA + GT+ Q LQ PG + G F G
Sbjct: 1402 QNNMPGIQGATSSPQPQATLFHNTAGGTMNQ---------LQNSPGSSQQTSGMFLFG-- 1450
Query: 983 YPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMP-SLPGQQGTSQARPM 1041
+ N + T PA + Q+M S PGQ ++ +P
Sbjct: 1451 -----------------------IQNNCSQLLTSGPATLPDQLMAISQPGQP-QNEGQPP 1486
Query: 1042 VMSGLSQGVP-GMPAFSQPPAQQQIPSGSFAPSSQSQ 1077
V + LSQ +P P S Q I S Q+Q
Sbjct: 1487 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQ 1523
Score = 52.0 bits (123), Expect = 3e-06
Identities = 101/488 (20%), Positives = 177/488 (36%), Gaps = 56/488 (11%)
Query: 457 VPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSP 516
+P++ M+P + ++ ++ +K+ + + QQ + SN N
Sbjct: 588 IPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGN--- 644
Query: 517 LGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQ 576
G SSP + +E + P+A+N P +Q ++ ++ +Q
Sbjct: 645 -GSFSSPSSSHLPSENEKQQQIQPKAYN------PETLTTIQTQDISQPGTFPAVSASSQ 697
Query: 577 QPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQ 636
PN+ ++L +Q T+ +D + N + L QQQQQ
Sbjct: 698 LPNS---DALLQQATQFQTRETQSREILQSDGTV--------VNLSQLTEASQQQQQSPL 746
Query: 637 QQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL 696
Q+Q Q QQQ +P + +S+ Q + + Q G A + S Q +
Sbjct: 747 QEQAQTLQQQISSNIFPSPNS-VSQLQNTIQQL-QAGSFTGSTASGSSGSVDLVQQVLEA 804
Query: 697 PRTTGPMQSSVPPGSGGMV---------------SGASPAGPGFLGSQPQAAIMKQMLID 741
+ + S P G+ + SG SP F ++P L+
Sbjct: 805 QQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGM--FSSTEPTVHTRPDNLLP 862
Query: 742 QRAQLIEQQKQQFLREQRQQQQQQQQILAE-----QQLQQSHL-PRQHLQPQRNPYPVQQ 795
RA+ + Q + L Q+QQQQQQQQ++ ++QQS +Q + P
Sbjct: 863 GRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASA 922
Query: 796 VNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAP 855
Q SP ++ + ++ T+ M + P+ + +T Q +A
Sbjct: 923 NGNLQQSP---VYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQ---VAT 976
Query: 856 YSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSML 915
TT + TQ Q N ++ Q G QP V + S M
Sbjct: 977 PGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQ----VNLFSSTKSMMS 1032
Query: 916 VNSAITQQ 923
V ++ TQQ
Sbjct: 1033 VQNSGTQQ 1040
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 72.4 bits (176), Expect = 2e-12
Identities = 128/579 (22%), Positives = 205/579 (35%), Gaps = 81/579 (13%)
Query: 176 QQNGACDGNFSPT-SKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGT 234
Q + + DG + T +K+I+ + M + + N P + K + +QNSGT
Sbjct: 1000 QTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFS----STKSMMSVQNSGT 1055
Query: 235 HTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSN 294
G NG + LQS + Q+ S+ L +
Sbjct: 1056 QQQG------------------NGLFQQGNEMMSLQSGNFLQQS-------SHSQAQLFH 1090
Query: 295 QNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQES 354
+D QE Q + N + +E + P F +T L S
Sbjct: 1091 PQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQP---PMFHSQSTIAVLQGSS 1147
Query: 355 ASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCA 414
++ + M + Q + F+ + S+ + ST + A+
Sbjct: 1148 VPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPN---SISPLQSTSNSEQQAAFQQQAP 1204
Query: 415 VQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQ 474
+ QTP + Q PP+ G L P VA+ S +P Q +Q
Sbjct: 1205 ISHIQTPMLSQEQAQ-PPQQG---LFQPQ-----------VALGSLPPNPMPQSQQGTMF 1249
Query: 475 QQQRAKL-MQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKP 533
Q Q + + MQ Q+QQQQQQQQQQQQQQQQ S SN + + +SP ++P
Sbjct: 1250 QSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASP-------KQP 1302
Query: 534 NSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNIL 593
M++ NP PMAN Q+ + + Q++M +NQ+ + S + ++
Sbjct: 1303 PPNMIF-------NPNQNPMANQEQQ-NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1354
Query: 594 TYGNTK------PLTHFNADLSQRMTPPVANPNKNPL------MPYIQQQQQQQQQQQQQ 641
G T+ PL H + + P + + L M +Q QQ QQ
Sbjct: 1355 NPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSP 1414
Query: 642 QQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTG 701
Q P +Q + + Q L G MNQ G+
Sbjct: 1415 LYSPQNNMPGIQGATSS-PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1473
Query: 702 PMQSSVPPGSGGMVSGAS-PAGPGFLGSQPQAAIMKQML 739
+ +S P + S P P G P ++ Q +
Sbjct: 1474 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQM 1512
Score = 60.8 bits (146), Expect = 7e-09
Identities = 166/817 (20%), Positives = 280/817 (34%), Gaps = 192/817 (23%)
Query: 288 SETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPAT- 346
SE +LSNQ + Q+ Q++++ A V E +Q + + + F A+
Sbjct: 889 SENTLSNQQQ-------QQQQQQQVMESSAAMVME--MQQSICQAAAQIQSELFPSTASA 939
Query: 347 -----ETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTP 401
++P+ Q+++ + S S + + + P+ SG ST +T + + +T
Sbjct: 940 NGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQ-QVATPGTTM 998
Query: 402 AAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSD 461
+ + Q+ Q N G+ N V + S ++V +S
Sbjct: 999 FQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGD----NQPQVNLFSSTKSMMSVQNS- 1053
Query: 462 MSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPS 521
QQQ Q + Q QQ Q Q Q
Sbjct: 1054 ----------GTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQ 1103
Query: 522 SPYGAAFTAEKP---------NSPMMYPQAFNNQNPIVPPMANNL--QKTTMNNYLPQNH 570
G+ F + P +S M P F++Q+ I +++ + + N +L Q+
Sbjct: 1104 ETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSP 1163
Query: 571 MNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQ 630
MN NL TN++ ++ + PL
Sbjct: 1164 MN-------NLQTNTVAQEAFFAAPNSISPL----------------------------- 1187
Query: 631 QQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQE 690
Q +QQ QQQ P +Q P LS++Q + Q+G+ +A +LP +
Sbjct: 1188 -QSTSNSEQQAAFQQQAPISHIQTPM--LSQEQAQ---PPQQGLFQPQVALGSLPPNPMP 1241
Query: 691 QHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQ 750
Q G T Q S+ + SP+ ++Q
Sbjct: 1242 QSQQG---TMFQSQHSIVA-----MQSNSPS--------------------------QEQ 1267
Query: 751 KQQFLREQRQQQQQQQQILAEQQLQQSHL-------PRQHLQPQRNPYPVQQVNQFQGSP 803
+QQ ++Q+QQQQQQQ IL Q + + P P +NP NQ Q
Sbjct: 1268 QQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP----MANQEQ--- 1320
Query: 804 QDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQ 863
Q+ + Q+ + M + Q + QNPG + ++Q+ + + ++P Q
Sbjct: 1321 QNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPL----FHSSPQIQ 1376
Query: 864 PGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQ 923
+ S+ Q+ + + MS + + Q + S +
Sbjct: 1377 LVQGSPSSQEQQVTLFLSPASMS------------------ALQTSINQQDMQQSPLYSP 1418
Query: 924 HPQMKGPVG-QALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGAS 982
M G G + P+PQA + GT+ Q LQ PG + G F G
Sbjct: 1419 QNNMPGIQGATSSPQPQATLFHNTAGGTMNQ---------LQNSPGSSQQTSGMFLFG-- 1467
Query: 983 YPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMP-SLPGQQGTSQARPM 1041
+ N + T PA + Q+M S PGQ ++ +P
Sbjct: 1468 -----------------------IQNNCSQLLTSGPATLPDQLMAISQPGQP-QNEGQPP 1503
Query: 1042 VMSGLSQGVP-GMPAFSQPPAQQQIPSGSFAPSSQSQ 1077
V + LSQ +P P S Q I S Q+Q
Sbjct: 1504 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQ 1540
Score = 53.1 bits (126), Expect = 1e-06
Identities = 111/541 (20%), Positives = 194/541 (35%), Gaps = 65/541 (12%)
Query: 404 PNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMS 463
P+PA+ N V+ + +P RP + A T + +P++ M+
Sbjct: 561 PDPAAGALNVNVKKEIS---------SPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMT 611
Query: 464 PAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSP 523
P + ++ ++ +K+ + + QQ + SN N G SSP
Sbjct: 612 PLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGN----GSFSSP 667
Query: 524 YGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGT 583
+ +E + P+A+N P +Q ++ ++ +Q PN+
Sbjct: 668 SSSHLPSENEKQQQIQPKAYN------PETLTTIQTQDISQPGTFPAVSASSQLPNS--- 718
Query: 584 NSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQ 643
++L +Q T+ +D + N + L QQQQQ Q+Q Q
Sbjct: 719 DALLQQATQFQTRETQSREILQSDGTV--------VNLSQLTEASQQQQQSPLQEQAQTL 770
Query: 644 QQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPM 703
QQQ +P + +S+ Q + + Q G A + S Q + + +
Sbjct: 771 QQQISSNIFPSPNS-VSQLQNTIQQL-QAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSV 828
Query: 704 QSSVPPGSGGMV---------------SGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIE 748
S P G+ + SG SP F ++P L+ RA+ +
Sbjct: 829 LFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGM--FSSTEPTVHTRPDNLLPGRAESVH 886
Query: 749 QQKQQFLREQRQQQQQQQQILAE-----QQLQQSHL-PRQHLQPQRNPYPVQQVNQFQGS 802
Q + L Q+QQQQQQQQ++ ++QQS +Q + P Q S
Sbjct: 887 PQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQS 946
Query: 803 PQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTS 862
P ++ + ++ T+ M + P+ + +T Q +A TT
Sbjct: 947 P---VYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQ---VATPGTTMFQ 1000
Query: 863 QPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQ 922
+ TQ Q N ++ Q G QP V + S M V ++ TQ
Sbjct: 1001 TSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQ----VNLFSSTKSMMSVQNSGTQ 1056
Query: 923 Q 923
Q
Sbjct: 1057 Q 1057
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 72.4 bits (176), Expect = 2e-12
Identities = 128/579 (22%), Positives = 205/579 (35%), Gaps = 81/579 (13%)
Query: 176 QQNGACDGNFSPT-SKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGT 234
Q + + DG + T +K+I+ + M + + N P + K + +QNSGT
Sbjct: 1001 QTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFS----STKSMMSVQNSGT 1056
Query: 235 HTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSN 294
G NG + LQS + Q+ S+ L +
Sbjct: 1057 QQQG------------------NGLFQQGNEMMSLQSGNFLQQS-------SHSQAQLFH 1091
Query: 295 QNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQES 354
+D QE Q + N + +E + P F +T L S
Sbjct: 1092 PQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQP---PMFHSQSTIAVLQGSS 1148
Query: 355 ASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCA 414
++ + M + Q + F+ + S+ + ST + A+
Sbjct: 1149 VPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPN---SISPLQSTSNSEQQAAFQQQAP 1205
Query: 415 VQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQ 474
+ QTP + Q PP+ G L P VA+ S +P Q +Q
Sbjct: 1206 ISHIQTPMLSQEQAQ-PPQQG---LFQPQ-----------VALGSLPPNPMPQSQQGTMF 1250
Query: 475 QQQRAKL-MQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKP 533
Q Q + + MQ Q+QQQQQQQQQQQQQQQQ S SN + + +SP ++P
Sbjct: 1251 QSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASP-------KQP 1303
Query: 534 NSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNIL 593
M++ NP PMAN Q+ + + Q++M +NQ+ + S + ++
Sbjct: 1304 PPNMIF-------NPNQNPMANQEQQ-NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1355
Query: 594 TYGNTK------PLTHFNADLSQRMTPPVANPNKNPL------MPYIQQQQQQQQQQQQQ 641
G T+ PL H + + P + + L M +Q QQ QQ
Sbjct: 1356 NPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSP 1415
Query: 642 QQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTG 701
Q P +Q + + Q L G MNQ G+
Sbjct: 1416 LYSPQNNMPGIQGATSS-PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1474
Query: 702 PMQSSVPPGSGGMVSGAS-PAGPGFLGSQPQAAIMKQML 739
+ +S P + S P P G P ++ Q +
Sbjct: 1475 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQM 1513
Score = 60.8 bits (146), Expect = 7e-09
Identities = 166/817 (20%), Positives = 280/817 (34%), Gaps = 192/817 (23%)
Query: 288 SETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPAT- 346
SE +LSNQ + Q+ Q++++ A V E +Q + + + F A+
Sbjct: 890 SENTLSNQQQ-------QQQQQQQVMESSAAMVME--MQQSICQAAAQIQSELFPSTASA 940
Query: 347 -----ETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTP 401
++P+ Q+++ + S S + + + P+ SG ST +T + + +T
Sbjct: 941 NGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQ-QVATPGTTM 999
Query: 402 AAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSD 461
+ + Q+ Q N G+ N V + S ++V +S
Sbjct: 1000 FQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGD----NQPQVNLFSSTKSMMSVQNS- 1054
Query: 462 MSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPS 521
QQQ Q + Q QQ Q Q Q
Sbjct: 1055 ----------GTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQ 1104
Query: 522 SPYGAAFTAEKP---------NSPMMYPQAFNNQNPIVPPMANNL--QKTTMNNYLPQNH 570
G+ F + P +S M P F++Q+ I +++ + + N +L Q+
Sbjct: 1105 ETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSP 1164
Query: 571 MNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQ 630
MN NL TN++ ++ + PL
Sbjct: 1165 MN-------NLQTNTVAQEAFFAAPNSISPL----------------------------- 1188
Query: 631 QQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQE 690
Q +QQ QQQ P +Q P LS++Q + Q+G+ +A +LP +
Sbjct: 1189 -QSTSNSEQQAAFQQQAPISHIQTPM--LSQEQAQ---PPQQGLFQPQVALGSLPPNPMP 1242
Query: 691 QHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQ 750
Q G T Q S+ + SP+ ++Q
Sbjct: 1243 QSQQG---TMFQSQHSIVA-----MQSNSPS--------------------------QEQ 1268
Query: 751 KQQFLREQRQQQQQQQQILAEQQLQQSHL-------PRQHLQPQRNPYPVQQVNQFQGSP 803
+QQ ++Q+QQQQQQQ IL Q + + P P +NP NQ Q
Sbjct: 1269 QQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP----MANQEQ--- 1321
Query: 804 QDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQ 863
Q+ + Q+ + M + Q + QNPG + ++Q+ + + ++P Q
Sbjct: 1322 QNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPL----FHSSPQIQ 1377
Query: 864 PGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQ 923
+ S+ Q+ + + MS + + Q + S +
Sbjct: 1378 LVQGSPSSQEQQVTLFLSPASMS------------------ALQTSINQQDMQQSPLYSP 1419
Query: 924 HPQMKGPVG-QALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGAS 982
M G G + P+PQA + GT+ Q LQ PG + G F G
Sbjct: 1420 QNNMPGIQGATSSPQPQATLFHNTAGGTMNQ---------LQNSPGSSQQTSGMFLFG-- 1468
Query: 983 YPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMP-SLPGQQGTSQARPM 1041
+ N + T PA + Q+M S PGQ ++ +P
Sbjct: 1469 -----------------------IQNNCSQLLTSGPATLPDQLMAISQPGQP-QNEGQPP 1504
Query: 1042 VMSGLSQGVP-GMPAFSQPPAQQQIPSGSFAPSSQSQ 1077
V + LSQ +P P S Q I S Q+Q
Sbjct: 1505 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQ 1541
Score = 52.0 bits (123), Expect = 3e-06
Identities = 101/488 (20%), Positives = 177/488 (36%), Gaps = 56/488 (11%)
Query: 457 VPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSP 516
+P++ M+P + ++ ++ +K+ + + QQ + SN N
Sbjct: 606 IPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGN--- 662
Query: 517 LGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQ 576
G SSP + +E + P+A+N P +Q ++ ++ +Q
Sbjct: 663 -GSFSSPSSSHLPSENEKQQQIQPKAYN------PETLTTIQTQDISQPGTFPAVSASSQ 715
Query: 577 QPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQ 636
PN+ ++L +Q T+ +D + N + L QQQQQ
Sbjct: 716 LPNS---DALLQQATQFQTRETQSREILQSDGTV--------VNLSQLTEASQQQQQSPL 764
Query: 637 QQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL 696
Q+Q Q QQQ +P + +S+ Q + + Q G A + S Q +
Sbjct: 765 QEQAQTLQQQISSNIFPSPNS-VSQLQNTIQQL-QAGSFTGSTASGSSGSVDLVQQVLEA 822
Query: 697 PRTTGPMQSSVPPGSGGMV---------------SGASPAGPGFLGSQPQAAIMKQMLID 741
+ + S P G+ + SG SP F ++P L+
Sbjct: 823 QQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGM--FSSTEPTVHTRPDNLLP 880
Query: 742 QRAQLIEQQKQQFLREQRQQQQQQQQILAE-----QQLQQSHL-PRQHLQPQRNPYPVQQ 795
RA+ + Q + L Q+QQQQQQQQ++ ++QQS +Q + P
Sbjct: 881 GRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASA 940
Query: 796 VNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAP 855
Q SP ++ + ++ T+ M + P+ + +T Q +A
Sbjct: 941 NGNLQQSP---VYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQ---VAT 994
Query: 856 YSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSML 915
TT + TQ Q N ++ Q G QP V + S M
Sbjct: 995 PGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQ----VNLFSSTKSMMS 1050
Query: 916 VNSAITQQ 923
V ++ TQQ
Sbjct: 1051 VQNSGTQQ 1058
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 72.4 bits (176), Expect = 2e-12
Identities = 128/579 (22%), Positives = 205/579 (35%), Gaps = 81/579 (13%)
Query: 176 QQNGACDGNFSPT-SKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGT 234
Q + + DG + T +K+I+ + M + + N P + K + +QNSGT
Sbjct: 907 QTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFS----STKSMMSVQNSGT 962
Query: 235 HTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSN 294
G NG + LQS + Q+ S+ L +
Sbjct: 963 QQQG------------------NGLFQQGNEMMSLQSGNFLQQS-------SHSQAQLFH 997
Query: 295 QNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQES 354
+D QE Q + N + +E + P F +T L S
Sbjct: 998 PQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQP---PMFHSQSTIAVLQGSS 1054
Query: 355 ASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCA 414
++ + M + Q + F+ + S+ + ST + A+
Sbjct: 1055 VPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPN---SISPLQSTSNSEQQAAFQQQAP 1111
Query: 415 VQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQ 474
+ QTP + Q PP+ G L P VA+ S +P Q +Q
Sbjct: 1112 ISHIQTPMLSQEQAQ-PPQQG---LFQPQ-----------VALGSLPPNPMPQSQQGTMF 1156
Query: 475 QQQRAKL-MQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKP 533
Q Q + + MQ Q+QQQQQQQQQQQQQQQQ S SN + + +SP ++P
Sbjct: 1157 QSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASP-------KQP 1209
Query: 534 NSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNIL 593
M++ NP PMAN Q+ + + Q++M +NQ+ + S + ++
Sbjct: 1210 PPNMIF-------NPNQNPMANQEQQ-NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1261
Query: 594 TYGNTK------PLTHFNADLSQRMTPPVANPNKNPL------MPYIQQQQQQQQQQQQQ 641
G T+ PL H + + P + + L M +Q QQ QQ
Sbjct: 1262 NPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSP 1321
Query: 642 QQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTG 701
Q P +Q + + Q L G MNQ G+
Sbjct: 1322 LYSPQNNMPGIQGATSS-PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1380
Query: 702 PMQSSVPPGSGGMVSGAS-PAGPGFLGSQPQAAIMKQML 739
+ +S P + S P P G P ++ Q +
Sbjct: 1381 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQM 1419
Score = 60.8 bits (146), Expect = 7e-09
Identities = 166/817 (20%), Positives = 280/817 (34%), Gaps = 192/817 (23%)
Query: 288 SETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPAT- 346
SE +LSNQ + Q+ Q++++ A V E +Q + + + F A+
Sbjct: 796 SENTLSNQQQ-------QQQQQQQVMESSAAMVME--MQQSICQAAAQIQSELFPSTASA 846
Query: 347 -----ETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTP 401
++P+ Q+++ + S S + + + P+ SG ST +T + + +T
Sbjct: 847 NGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQ-QVATPGTTM 905
Query: 402 AAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSD 461
+ + Q+ Q N G+ N V + S ++V +S
Sbjct: 906 FQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGD----NQPQVNLFSSTKSMMSVQNS- 960
Query: 462 MSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPS 521
QQQ Q + Q QQ Q Q Q
Sbjct: 961 ----------GTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQ 1010
Query: 522 SPYGAAFTAEKP---------NSPMMYPQAFNNQNPIVPPMANNL--QKTTMNNYLPQNH 570
G+ F + P +S M P F++Q+ I +++ + + N +L Q+
Sbjct: 1011 ETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSP 1070
Query: 571 MNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQ 630
MN NL TN++ ++ + PL
Sbjct: 1071 MN-------NLQTNTVAQEAFFAAPNSISPL----------------------------- 1094
Query: 631 QQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQE 690
Q +QQ QQQ P +Q P LS++Q + Q+G+ +A +LP +
Sbjct: 1095 -QSTSNSEQQAAFQQQAPISHIQTPM--LSQEQAQ---PPQQGLFQPQVALGSLPPNPMP 1148
Query: 691 QHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQ 750
Q G T Q S+ + SP+ ++Q
Sbjct: 1149 QSQQG---TMFQSQHSIVA-----MQSNSPS--------------------------QEQ 1174
Query: 751 KQQFLREQRQQQQQQQQILAEQQLQQSHL-------PRQHLQPQRNPYPVQQVNQFQGSP 803
+QQ ++Q+QQQQQQQ IL Q + + P P +NP NQ Q
Sbjct: 1175 QQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP----MANQEQ--- 1227
Query: 804 QDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQ 863
Q+ + Q+ + M + Q + QNPG + ++Q+ + + ++P Q
Sbjct: 1228 QNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPL----FHSSPQIQ 1283
Query: 864 PGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQ 923
+ S+ Q+ + + MS + + Q + S +
Sbjct: 1284 LVQGSPSSQEQQVTLFLSPASMS------------------ALQTSINQQDMQQSPLYSP 1325
Query: 924 HPQMKGPVG-QALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGAS 982
M G G + P+PQA + GT+ Q LQ PG + G F G
Sbjct: 1326 QNNMPGIQGATSSPQPQATLFHNTAGGTMNQ---------LQNSPGSSQQTSGMFLFG-- 1374
Query: 983 YPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMP-SLPGQQGTSQARPM 1041
+ N + T PA + Q+M S PGQ ++ +P
Sbjct: 1375 -----------------------IQNNCSQLLTSGPATLPDQLMAISQPGQP-QNEGQPP 1410
Query: 1042 VMSGLSQGVP-GMPAFSQPPAQQQIPSGSFAPSSQSQ 1077
V + LSQ +P P S Q I S Q+Q
Sbjct: 1411 VTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQ 1447
Score = 52.0 bits (123), Expect = 3e-06
Identities = 101/488 (20%), Positives = 177/488 (36%), Gaps = 56/488 (11%)
Query: 457 VPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSP 516
+P++ M+P + ++ ++ +K+ + + QQ + SN N
Sbjct: 512 IPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGN--- 568
Query: 517 LGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQ 576
G SSP + +E + P+A+N P +Q ++ ++ +Q
Sbjct: 569 -GSFSSPSSSHLPSENEKQQQIQPKAYN------PETLTTIQTQDISQPGTFPAVSASSQ 621
Query: 577 QPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQ 636
PN+ ++L +Q T+ +D + N + L QQQQQ
Sbjct: 622 LPNS---DALLQQATQFQTRETQSREILQSDGTV--------VNLSQLTEASQQQQQSPL 670
Query: 637 QQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL 696
Q+Q Q QQQ +P + +S+ Q + + Q G A + S Q +
Sbjct: 671 QEQAQTLQQQISSNIFPSPNS-VSQLQNTIQQL-QAGSFTGSTASGSSGSVDLVQQVLEA 728
Query: 697 PRTTGPMQSSVPPGSGGMV---------------SGASPAGPGFLGSQPQAAIMKQMLID 741
+ + S P G+ + SG SP F ++P L+
Sbjct: 729 QQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGM--FSSTEPTVHTRPDNLLP 786
Query: 742 QRAQLIEQQKQQFLREQRQQQQQQQQILAE-----QQLQQSHL-PRQHLQPQRNPYPVQQ 795
RA+ + Q + L Q+QQQQQQQQ++ ++QQS +Q + P
Sbjct: 787 GRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASA 846
Query: 796 VNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAP 855
Q SP ++ + ++ T+ M + P+ + +T Q +A
Sbjct: 847 NGNLQQSP---VYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQ---VAT 900
Query: 856 YSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSML 915
TT + TQ Q N ++ Q G QP V + S M
Sbjct: 901 PGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQ----VNLFSSTKSMMS 956
Query: 916 VNSAITQQ 923
V ++ TQQ
Sbjct: 957 VQNSGTQQ 964
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 71.2 bits (173), Expect = 5e-12
Identities = 97/394 (24%), Positives = 143/394 (36%), Gaps = 83/394 (21%)
Query: 350 LSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASS 409
L S+S + P P++ S S A SSS S+ S+A+ P+ + P+ P+
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSSS----SSSSSASPFPASQALPSYPHSFPP 414
Query: 410 PANCAVQS-------PQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDM 462
P + +V + P P+QA PP P G LL A S + P P S
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLL-------ANSNAHPGPFPPSTG 467
Query: 463 SPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSS 522
+ + ++ QQQQQQQQQQQQQQQQQQQ H N P P +
Sbjct: 468 AQSTAHPPVSTHHHHH--------QQQQQQQQQQQQQQQQQQQHHGNS----GPPPPGAF 515
Query: 523 PYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQ--PNN 580
P+ + P + + P P A +LP H + Q PN
Sbjct: 516 PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA----------HLPPPHSQVSYSQAGPNG 565
Query: 581 LGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQ 640
+S + + + G + P +H +P++ P Q
Sbjct: 566 PPVSSSSNSSSSTSQG-SYPCSH-------------PSPSQGP----------------Q 595
Query: 641 QQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTT 700
PP P + A LS V + P Y G + P +
Sbjct: 596 GAPYPFPPVPTVTTSSATLS--------TVIATVASSPAGYKTASPPGPPPYGKRAP-SP 646
Query: 701 GPMQSSVPPG--SGGMVSGASPAGPGFLGSQPQA 732
G +++ PPG G S + PG+ G+ P A
Sbjct: 647 GAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPA 680
Score = 54.7 bits (130), Expect = 5e-07
Identities = 100/417 (23%), Positives = 131/417 (31%), Gaps = 113/417 (27%)
Query: 344 PATETPLSQESASVK-SDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPA 402
P TP+S S+ + P+ P V G+ + P PP + +LP
Sbjct: 254 PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAP----PPANFPHVTPNLP------- 302
Query: 403 APNPASSPANCAVQSPQ----TPNQAHTP---------GQAPPRPGNGYLLNPAAVTVAG 449
P PA P N A SP P H P G PP P G L P+ ++
Sbjct: 303 -PPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP- 360
Query: 450 SASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSN 509
P+S +PA ++ + + Q HS
Sbjct: 361 --------PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412
Query: 510 QTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQN 569
PP + + K P + QA +Q P PP L +
Sbjct: 413 ---------PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANS-------- 455
Query: 570 HMNMINQQPNNL--GTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPY 627
N P T + + H PPV+ + +
Sbjct: 456 -----NAHPGPFPPSTGAQSTAH-----------------------PPVSTHHHHH---- 483
Query: 628 IQQQQQQQQQQQQQQQQQQ-------PPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMA 680
QQQQQQQQQQQQQQQQQQ PPPP H E G +
Sbjct: 484 -QQQQQQQQQQQQQQQQQQQHHGNSGPPPP---GAFPHPLEG----------GSSHHAHP 529
Query: 681 YAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQ 737
YA PS G + P GP PP S S A P GP S ++ Q
Sbjct: 530 YAMSPSLGSLR-----PYPPGPAHLP-PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
Score = 48.1 bits (113), Expect = 5e-05
Identities = 181/918 (19%), Positives = 275/918 (29%), Gaps = 217/918 (23%)
Query: 225 PSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTC 284
P L++ G +PG + S +G+ + + +E++ T +K + E + +
Sbjct: 23 PREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKAR-VEEASTPKVNKQGRSEEISES-- 79
Query: 285 IDTSETSLSNQNKLFSDI-------NLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKK 337
++ ET+ + K ++ +L+ + + L D+ ++ P D QD
Sbjct: 80 -ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDD-GSSDPRDIDQD------NRST 131
Query: 338 EPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSV 397
P P + S S+ + P+ P+ P P S PP ST P
Sbjct: 132 SPSIYSPGSVENDSDSSSGLSQGPAR-PYH-----PPPLFPPSPQPPDST-------PRQ 178
Query: 398 ASTPAAPNPASSPANC-AVQSPQTPNQAHTPGQAPPR-----PGN--GYLLNPAAVTVAG 449
P+P+ +P A P T P APP PG G L P G
Sbjct: 179 PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGG 238
Query: 450 SASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSN 509
A+ V P+ +Q S+
Sbjct: 239 GAASSVGGPNGG---------------------------------KQHPPPTTPISVSSS 265
Query: 510 QTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMN------ 563
S P PP++P G P P +P N P PP L + +
Sbjct: 266 GASGAPPTKPPTTPVGGGNLPSAP-PPANFPHVTPNLPP--PPALRPLNNASASPPGLGA 322
Query: 564 ----NYLPQNH-----MNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTP 614
+LP H M + P G H++ ++ P + M
Sbjct: 323 QPLPGHLPSPHAMGQGMGGLPPGPEK-GPTLAPSPHSLPPASSSAP--------APPMRF 373
Query: 615 PVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGV 674
P ++ + + Q P P P LS V
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS-------------V 420
Query: 675 MNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAI 734
NQP Y PS LP Q PP G + S A PG A
Sbjct: 421 SNQPPKYTQ-PS---------LPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQS 470
Query: 735 MKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQ 794
+ Q+QQQQQQQQ +QQ QQ H P P+P++
Sbjct: 471 TAHPPVSTHHH----------HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
Query: 795 QVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLA 854
+ P A + S L
Sbjct: 521 GGSSHHAHPY----------------------------------------AMSPSLGSLR 540
Query: 855 PYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSM 914
PY P P ++ ++++QA GP P S Q
Sbjct: 541 PYPPGPAHLPPPHS-----------------QVSYSQA-GPNGPPVSSSSNSSSSTSQGS 582
Query: 915 LVNSAITQQHPQ-MKGPVGQALPRPQAP------PRLQSLMGTVQQGAQSWQQRSLQGMP 967
S HP +GP G P P P L +++ TV ++ S G P
Sbjct: 583 YPCS-----HPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
Query: 968 --GRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVR----TLNPAAM 1021
G+ + G + + G P + P G + A GT + T+ P +
Sbjct: 638 PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPL 697
Query: 1022 ---GRQMMPSLPGQQGTSQARPMVMSGLSQGVPG----MPAFSQPPAQQQIPSGSF--AP 1072
G +PSLP + P + + + P P PPA+ P P
Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVP 757
Query: 1073 SSQSQAYERNAPQDVSYN 1090
S SQ+ N D +N
Sbjct: 758 SHASQSARFNKHLDRGFN 775
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/216 (21%), Positives = 92/216 (42%), Gaps = 33/216 (15%)
Query: 336 KKEPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTA---- 391
K+ P T TP + S S + +P + SP A P + P TV
Sbjct: 641 KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT-SPPAGPGTFKPGSPTVGPGPLPP 699
Query: 392 ---TSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVA 448
+ LPS+ PAAP AS P A Q Q P + + ++P P P V V
Sbjct: 700 AGPSGLPSLPPPPAAP--ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVP 757
Query: 449 GSAS-----------GPVAVPSSDM------------SPAEQLKQMAAQQQQRAKLMQQK 485
AS G + SD+ A+ ++++ + +QRA+ +++
Sbjct: 758 SHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKER 817
Query: 486 QQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPS 521
+++++++++++++++++ ++ +P+ PS
Sbjct: 818 EREREREKEREREKERELERSVKLAQEGRAPVECPS 853
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 71.2 bits (173), Expect = 5e-12
Identities = 97/394 (24%), Positives = 143/394 (36%), Gaps = 83/394 (21%)
Query: 350 LSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASS 409
L S+S + P P++ S S A SSS S+ S+A+ P+ + P+ P+
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSSS----SSSSSASPFPASQALPSYPHSFPP 414
Query: 410 PANCAVQS-------PQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDM 462
P + +V + P P+QA PP P G LL A S + P P S
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLL-------ANSNAHPGPFPPSTG 467
Query: 463 SPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSS 522
+ + ++ QQQQQQQQQQQQQQQQQQQ H N P P +
Sbjct: 468 AQSTAHPPVSTHHHHH--------QQQQQQQQQQQQQQQQQQQHHGNS----GPPPPGAF 515
Query: 523 PYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQ--PNN 580
P+ + P + + P P A +LP H + Q PN
Sbjct: 516 PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA----------HLPPPHSQVSYSQAGPNG 565
Query: 581 LGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQ 640
+S + + + G + P +H +P++ P Q
Sbjct: 566 PPVSSSSNSSSSTSQG-SYPCSH-------------PSPSQGP----------------Q 595
Query: 641 QQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTT 700
PP P + A LS V + P Y G + P +
Sbjct: 596 GAPYPFPPVPTVTTSSATLS--------TVIATVASSPAGYKTASPPGPPPYGKRAP-SP 646
Query: 701 GPMQSSVPPG--SGGMVSGASPAGPGFLGSQPQA 732
G +++ PPG G S + PG+ G+ P A
Sbjct: 647 GAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPA 680
Score = 54.7 bits (130), Expect = 5e-07
Identities = 100/417 (23%), Positives = 131/417 (31%), Gaps = 113/417 (27%)
Query: 344 PATETPLSQESASVK-SDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPA 402
P TP+S S+ + P+ P V G+ + P PP + +LP
Sbjct: 254 PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAP----PPANFPHVTPNLP------- 302
Query: 403 APNPASSPANCAVQSPQ----TPNQAHTP---------GQAPPRPGNGYLLNPAAVTVAG 449
P PA P N A SP P H P G PP P G L P+ ++
Sbjct: 303 -PPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP- 360
Query: 450 SASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSN 509
P+S +PA ++ + + Q HS
Sbjct: 361 --------PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412
Query: 510 QTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQN 569
PP + + K P + QA +Q P PP L +
Sbjct: 413 ---------PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANS-------- 455
Query: 570 HMNMINQQPNNL--GTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPY 627
N P T + + H PPV+ + +
Sbjct: 456 -----NAHPGPFPPSTGAQSTAH-----------------------PPVSTHHHHH---- 483
Query: 628 IQQQQQQQQQQQQQQQQQQ-------PPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMA 680
QQQQQQQQQQQQQQQQQQ PPPP H E G +
Sbjct: 484 -QQQQQQQQQQQQQQQQQQQHHGNSGPPPP---GAFPHPLEG----------GSSHHAHP 529
Query: 681 YAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQ 737
YA PS G + P GP PP S S A P GP S ++ Q
Sbjct: 530 YAMSPSLGSLR-----PYPPGPAHLP-PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
Score = 48.1 bits (113), Expect = 5e-05
Identities = 181/918 (19%), Positives = 275/918 (29%), Gaps = 217/918 (23%)
Query: 225 PSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTC 284
P L++ G +PG + S +G+ + + +E++ T +K + E + +
Sbjct: 23 PREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKAR-VEEASTPKVNKQGRSEEISES-- 79
Query: 285 IDTSETSLSNQNKLFSDI-------NLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKK 337
++ ET+ + K ++ +L+ + + L D+ ++ P D QD
Sbjct: 80 -ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDD-GSSDPRDIDQD------NRST 131
Query: 338 EPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSV 397
P P + S S+ + P+ P+ P P S PP ST P
Sbjct: 132 SPSIYSPGSVENDSDSSSGLSQGPAR-PYH-----PPPLFPPSPQPPDST-------PRQ 178
Query: 398 ASTPAAPNPASSPANC-AVQSPQTPNQAHTPGQAPPR-----PGN--GYLLNPAAVTVAG 449
P+P+ +P A P T P APP PG G L P G
Sbjct: 179 PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGG 238
Query: 450 SASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSN 509
A+ V P+ +Q S+
Sbjct: 239 GAASSVGGPNGG---------------------------------KQHPPPTTPISVSSS 265
Query: 510 QTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMN------ 563
S P PP++P G P P +P N P PP L + +
Sbjct: 266 GASGAPPTKPPTTPVGGGNLPSAP-PPANFPHVTPNLPP--PPALRPLNNASASPPGLGA 322
Query: 564 ----NYLPQNH-----MNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTP 614
+LP H M + P G H++ ++ P + M
Sbjct: 323 QPLPGHLPSPHAMGQGMGGLPPGPEK-GPTLAPSPHSLPPASSSAP--------APPMRF 373
Query: 615 PVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGV 674
P ++ + + Q P P P LS V
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS-------------V 420
Query: 675 MNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAI 734
NQP Y PS LP Q PP G + S A PG A
Sbjct: 421 SNQPPKYTQ-PS---------LPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQS 470
Query: 735 MKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQ 794
+ Q+QQQQQQQQ +QQ QQ H P P+P++
Sbjct: 471 TAHPPVSTHHH----------HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
Query: 795 QVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLA 854
+ P A + S L
Sbjct: 521 GGSSHHAHPY----------------------------------------AMSPSLGSLR 540
Query: 855 PYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSM 914
PY P P ++ ++++QA GP P S Q
Sbjct: 541 PYPPGPAHLPPPHS-----------------QVSYSQA-GPNGPPVSSSSNSSSSTSQGS 582
Query: 915 LVNSAITQQHPQ-MKGPVGQALPRPQAP------PRLQSLMGTVQQGAQSWQQRSLQGMP 967
S HP +GP G P P P L +++ TV ++ S G P
Sbjct: 583 YPCS-----HPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
Query: 968 --GRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVR----TLNPAAM 1021
G+ + G + + G P + P G + A GT + T+ P +
Sbjct: 638 PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPL 697
Query: 1022 ---GRQMMPSLPGQQGTSQARPMVMSGLSQGVPG----MPAFSQPPAQQQIPSGSF--AP 1072
G +PSLP + P + + + P P PPA+ P P
Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVP 757
Query: 1073 SSQSQAYERNAPQDVSYN 1090
S SQ+ N D +N
Sbjct: 758 SHASQSARFNKHLDRGFN 775
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/216 (21%), Positives = 92/216 (42%), Gaps = 33/216 (15%)
Query: 336 KKEPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTA---- 391
K+ P T TP + S S + +P + SP A P + P TV
Sbjct: 641 KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT-SPPAGPGTFKPGSPTVGPGPLPP 699
Query: 392 ---TSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVA 448
+ LPS+ PAAP AS P A Q Q P + + ++P P P V V
Sbjct: 700 AGPSGLPSLPPPPAAP--ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVP 757
Query: 449 GSAS-----------GPVAVPSSDM------------SPAEQLKQMAAQQQQRAKLMQQK 485
AS G + SD+ A+ ++++ + +QRA+ +++
Sbjct: 758 SHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKER 817
Query: 486 QQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPS 521
+++++++++++++++++ ++ +P+ PS
Sbjct: 818 EREREREKEREREKERELERSVKLAQEGRAPVECPS 853
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 69.3 bits (168), Expect = 2e-11
Identities = 51/148 (34%), Positives = 63/148 (42%), Gaps = 20/148 (13%)
Query: 416 QSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQ 475
Q +P A TPG + +P G P+ +S EQ +Q QQ
Sbjct: 12 QGLASPQGAMTPGIP--------IFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQ 63
Query: 476 QQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHS------------NQTSNWSPLGPPSSP 523
QQ+ + QQ+QQQQQQQQQQQQQQQQQQQQQ + T S P
Sbjct: 64 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFH 123
Query: 524 YGAAFTAEKPNSPMMYPQAFNNQNPIVP 551
TA P + +YP PI P
Sbjct: 124 SQTLTTAPLPGTTPLYPSPMTPMTPITP 151
Score = 49.7 bits (117), Expect = 2e-05
Identities = 50/161 (31%), Positives = 67/161 (41%), Gaps = 12/161 (7%)
Query: 705 SSVPPGSGGMVSGASPAGPG---FLGSQPQAAIMKQMLIDQRAQLI---EQQKQQFLREQ 758
+S+PP + G+ S PG F P + I L EQQ+QQ ++Q
Sbjct: 5 NSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQ 64
Query: 759 RQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSM 818
+QQQQQQQQ +QQ QQ +Q Q Q+ V Q S Q QA
Sbjct: 65 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQ-STSQQATQGTSGQAPQLFH 123
Query: 819 RTSRLMAQNAGMMGIGPS----QNPGTMATAAAQSEMGLAP 855
+ A G + PS P T AT A++S G+ P
Sbjct: 124 SQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESS-GIVP 163
Score = 48.1 bits (113), Expect = 5e-05
Identities = 38/120 (31%), Positives = 54/120 (45%), Gaps = 12/120 (10%)
Query: 612 MTP-PVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMK 670
+TP P+ N N ++ Q+QQQQQQQQQQQQQQQQ Q Q + + Q++
Sbjct: 38 LTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAV 97
Query: 671 QKGVMNQPMAYAALPS---------HGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPA 721
+ Q + A H Q LP TT S + P + ++ A+PA
Sbjct: 98 AAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMT--PITPATPA 155
Score = 43.9 bits (102), Expect = 9e-04
Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 5/112 (4%)
Query: 683 ALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQ 742
+LP + Q GL G M +P S M G + + + +Q Q
Sbjct: 6 SLPPYAQ-----GLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ 60
Query: 743 RAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQ 794
+ Q +QQ+QQ ++Q+QQQQQQQQ +QQ QQ + +Q + Q
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 68.9 bits (167), Expect = 3e-11
Identities = 85/291 (29%), Positives = 112/291 (38%), Gaps = 51/291 (17%)
Query: 466 EQLKQMAAQQQQRAKLMQQKQQQQQQQQQ----------QQQQQQQQQQQQHSNQTSNWS 515
+QL+Q QQQ KL Q QQQ QQQQQ QQQQQQQQQQQQ Q
Sbjct: 208 QQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267
Query: 516 PLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMIN 575
P P P PM PQ +Q +P + T + PQ +
Sbjct: 268 P--PIQQP------------PMQQPQPPPSQ--ALPQQLQQMHHTQHHQPPPQPQQPPVA 311
Query: 576 Q-QPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRM--TPPVANPNKNPLMPYIQQQQ 632
Q QP+ L S T+PL L +M T P + P++ +QQ
Sbjct: 312 QNQPSQLPPQS-----------QTQPLVSQAQALPGQMLYTQPPLKFVRAPMV--VQQPP 358
Query: 633 QQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHG---Q 689
Q Q QQQQ Q Q+ AP + + M + A +A+PS
Sbjct: 359 VQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLG 418
Query: 690 EQHPVGLPRTTGPMQSSVPPGSGGMVSGASP------AGPGFLGSQPQAAI 734
Q + +++ PM SS PG + P PG SQP + +
Sbjct: 419 RQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 469
Score = 67.4 bits (163), Expect = 7e-11
Identities = 122/530 (23%), Positives = 177/530 (33%), Gaps = 115/530 (21%)
Query: 411 ANCAVQSPQTPNQAHTPGQA--------PPR-PGN--GYLLNPAAVTVAGSASGPVAVPS 459
+ +V P Q+ T G A PPR PG G + + A+ S SG +
Sbjct: 74 SQASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGT 133
Query: 460 SDMSPAE-------------QLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQ 506
S M+P QL+Q+A QQQQ+ + QQ+QQ QQQQQQQQQQQ Q QQ
Sbjct: 134 SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQ 193
Query: 507 HSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYL 566
+ Q F A + Q Q+ I N Q L
Sbjct: 194 SAMQQQ---------------FQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL 238
Query: 567 PQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMP 626
+ + QQ +Q + + PP+ P P
Sbjct: 239 QRIAQLQLQQQQQQQQQQQQQQQQAL------------------QAQPPIQQPPMQQPQP 280
Query: 627 YIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPS 686
Q QQ QQ Q QPPP Q P A NQP + LP
Sbjct: 281 PPSQALPQQLQQMHHTQHHQPPPQPQQPPVA-----------------QNQP---SQLPP 320
Query: 687 HGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQL 746
Q Q V Q+ PG L +QP ++ ++ Q+ +
Sbjct: 321 QSQTQPLVS--------QAQALPGQ-------------MLYTQPPLKFVRAPMVVQQPPV 359
Query: 747 IEQQKQQFLREQRQQQQQQ----QQILAEQQLQQSHLPRQHLQP-------QRNPYPVQQ 795
Q +QQ Q Q Q Q++ E Q R P + P+ +
Sbjct: 360 QPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGR 419
Query: 796 VNQFQGSPQDIAAVRSQAALQSMRTSRLM---AQNAGMMGIGPSQNPGTMATAAAQSEMG 852
Q S + + S + Q ++T + M Q + G SQ +++ A S
Sbjct: 420 QPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSS 479
Query: 853 LAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQ 902
P +P+ QP ++ Q P+ ++ N + S Q
Sbjct: 480 FLP---SPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQ 526
Score = 57.4 bits (137), Expect = 8e-08
Identities = 105/450 (23%), Positives = 155/450 (34%), Gaps = 72/450 (16%)
Query: 669 MKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGP----- 723
M G M QPM+ + P G S + P S +VS A+P
Sbjct: 113 MGSLGAMGQPMSLSGQPPPGT---------------SGMAPHSMAVVSTATPQTQLQLQQ 157
Query: 724 -GFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQ------QQQQILAEQQLQQ 776
Q Q +Q + Q +QQ+QQF +Q QQ QQQQ L +QQ QQ
Sbjct: 158 VALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQ 217
Query: 777 SHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNA----GMMG 832
HL + H Q Q QQ+ Q Q Q IA ++ Q Q + + Q A +
Sbjct: 218 QHLIKLHHQNQ------QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ 271
Query: 833 IGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQA 892
P Q P + A ++ ++ P Q Q P QS +QA
Sbjct: 272 QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQA 331
Query: 893 QGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQ 952
Q GQ M+ V + + Q P ++ V Q Q Q + VQ
Sbjct: 332 QA----LPGQ---MLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQ 384
Query: 953 QGAQSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGT 1012
++ Q G + A +P + P G Q + + +
Sbjct: 385 MITEALAQ--------------GGMHIRARFPPTTAVSAIPSSSIPLG-RQPMAQVSQSS 429
Query: 1013 VRTLNPAAMGRQM----------MPSLPGQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQ 1062
+ L+ + G+Q+ PS Q +SQ V SG P +F P+
Sbjct: 430 LPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG---PAPSPSSFLPSPSP 486
Query: 1063 QQIPSGSFAPSSQSQAYERNAPQDVSYNYS 1092
Q S A + Q+ + P + N S
Sbjct: 487 QPSQSPVTARTPQNFSVPSPGPLNTPVNPS 516
Score = 36.2 bits (82), Expect = 0.18
Identities = 41/140 (29%), Positives = 53/140 (37%), Gaps = 15/140 (10%)
Query: 354 SASVKSDPSHS------PFAHVSMGSPQARPSSSGP-PFSTVSTATSLPSVASTPAAPNP 406
+ +V + PS S P A VS S P S P P V T S+P P
Sbjct: 404 TTAVSAIPSSSIPLGRQPMAQVSQSS---LPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQ 460
Query: 407 ASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVP---SSDMS 463
SS N V S P+ + P+P + + + GP+ P SS MS
Sbjct: 461 PSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMS 520
Query: 464 PAEQLKQMAAQQQQRAKLMQ 483
PA A +QQ KL Q
Sbjct: 521 PAG--SSQAEEQQYLDKLKQ 538
Score = 32.0 bits (71), Expect = 3.4
Identities = 82/449 (18%), Positives = 152/449 (33%), Gaps = 58/449 (12%)
Query: 27 GGAGIGVNNTPNSTPAAPSSNHPAAGGCGG-------SGGPGGGSAAVPKHSTVVERLRQ 79
G AGIG+ P P + G G SG P G++ + HS V
Sbjct: 95 GAAGIGM------PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTAT 148
Query: 80 RIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKPQ 139
+ V + + QQ Q +Q +++ + Q+ +Q+ ++ +QQ + Q
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQ---QQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQ 205
Query: 140 QDAEAASAEQRNHTLI--------MLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKR 191
Q + +Q+ LI +Q+ ++ A+ L QQ ++
Sbjct: 206 QQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ-------QQQQQQ 258
Query: 192 IRKDISAGMEAINNLPSNMPLPSASPL-------------HQLDLKPSLP--LQNSGTHT 236
++ I P P P S HQ +P P QN +
Sbjct: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318
Query: 237 PGLLED---LSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLS 293
P + +S+ LP L + ++Q ++ + T + T++ +
Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAA-- 376
Query: 294 NQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEP-----EFSQPATET 348
Q + + Q + A P + + + ++P + S P +
Sbjct: 377 -QMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSS 435
Query: 349 PLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPA-APNPA 407
P + P G P ++P+S+ S ++ LPS + P+ +P A
Sbjct: 436 PSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTA 495
Query: 408 SSPANCAVQSPQTPNQAHTPGQAPPRPGN 436
+P N +V SP N P G+
Sbjct: 496 RTPQNFSVPSPGPLNTPVNPSSVMSPAGS 524
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 67.4 bits (163), Expect = 7e-11
Identities = 116/500 (23%), Positives = 167/500 (33%), Gaps = 122/500 (24%)
Query: 328 LFNEDFEEKKEPEFSQPATETPLSQESASVKSDPSHSPFAHVS---MGSPQARPSSSGPP 384
++ E+ EE++E E + + ++ S KS P+ S S SP++ S
Sbjct: 187 IYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGE 246
Query: 385 FSTVSTATSLPSVASTPAAPNPASSPANCAVQS--PQ--TPNQAHTPGQAPPRPGN---- 436
++ S P PA P A + PQ P + PP PGN
Sbjct: 247 LMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPP 306
Query: 437 ---GYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMA-AQQQQRAKLMQQKQQQQQQQ 492
G L+ + S +A S + + A QQ R + Q
Sbjct: 307 EVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAP 366
Query: 493 QQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPP 552
+ +QQ QQ H+N + F+ K V P
Sbjct: 367 TKNLEQQVNHSQQGHTNANA-------------VLFSQVK-----------------VTP 396
Query: 553 MANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRM 612
+ LQ+ Q H +++ QP + +Q I SQ+
Sbjct: 397 ETHMLQQQQQAQQQQQQHP-VLHLQPQQIMQLQQQQQQQI----------------SQQP 439
Query: 613 TPPVANPNKNPLMPYIQQQQQQQQ--------QQQQQQQQQQPPPPQLQAPRAHLSEDQK 664
P + P P+ QQQQQQQQ QQ Q QQQ PP QL P+ L Q+
Sbjct: 440 YP------QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQ 493
Query: 665 RLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPG 724
+ L +Q H +QH
Sbjct: 494 QHALQQQ--------------FHQLQQHQ------------------------------- 508
Query: 725 FLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHL 784
L Q A + +Q + Q+ Q + Q+QQ R +QQQQQQ Q L Q+ QH
Sbjct: 509 -LQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQ 567
Query: 785 QPQRNPYPVQQVNQFQGSPQ 804
P + P QQ Q SPQ
Sbjct: 568 VPPQQPPQQQQQQQPPPSPQ 587
Score = 56.2 bits (134), Expect = 2e-07
Identities = 37/89 (41%), Positives = 46/89 (51%), Gaps = 8/89 (8%)
Query: 469 KQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAF 528
+Q AQ QQ+ L+QQ+QQQQ QQQQ Q+ QQQQQQQ +QT+ P S A
Sbjct: 511 QQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTA------PHLSQTSQAL 564
Query: 529 TAEKPNSPMMYPQAFNNQNPIVPPMANNL 557
+ P P PQ Q P P + L
Sbjct: 565 QHQVP--PQQPPQQQQQQQPPPSPQQHQL 591
Score = 53.9 bits (128), Expect = 8e-07
Identities = 84/400 (21%), Positives = 131/400 (32%), Gaps = 67/400 (16%)
Query: 463 SPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSS 522
SPA + + QQ K ++ + + + + NW+P P
Sbjct: 219 SPASSQEGSPSGDQQ----FSPKSNTEKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQ- 273
Query: 523 PYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLG 582
A K P N VPP+ N+ + L N+ + + + +
Sbjct: 274 -----LAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQNLQSSERSEMI 328
Query: 583 TNSLNKQHNILTYGNTKPLTHFN-----ADLSQRMTPPVAN------------PNKNPLM 625
+ N + N A + Q ++ P N N N ++
Sbjct: 329 ATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVL 388
Query: 626 ----PYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAY 681
+ QQQQQ QQQQQQ P LQ + + Q++ + +Q P +
Sbjct: 389 FSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPF 448
Query: 682 AALPSHGQEQHP--VGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQML 739
+ Q+ HP + P Q PP Q L
Sbjct: 449 SQQQQQQQQAHPHQFSQQQLQFPQQQLHPP---------------------------QQL 481
Query: 740 IDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQF 799
+ QL Q+Q L++Q Q QQ Q L +QQL Q LQ Q+ QQ Q
Sbjct: 482 HRPQQQLQPFQQQHALQQQFHQLQQHQ--LQQQQLAQLQQQHSLLQQQQQQQIQQQQLQR 539
Query: 800 QGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNP 839
Q ++SQ A +TS+ + + P Q P
Sbjct: 540 MHQQQQQQQMQSQTAPHLSQTSQALQHQ-----VPPQQPP 574
Score = 51.6 bits (122), Expect = 4e-06
Identities = 39/93 (41%), Positives = 48/93 (51%), Gaps = 8/93 (8%)
Query: 467 QLKQMAAQQQQRAKLMQQKQQQQQQQQQQ---QQQQQQQQQQQ---HSNQTSN-WSPLGP 519
Q +Q+A QQQ + L QQ+QQQ QQQQ Q QQQQQQQ Q Q H +QTS P
Sbjct: 510 QQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVP 569
Query: 520 PSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPP 552
P P + P SP + Q F + + P
Sbjct: 570 PQQPPQQQQQQQPPPSPQQH-QLFGHDPAVEIP 601
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 66.6 bits (161), Expect = 1e-10
Identities = 47/118 (39%), Positives = 55/118 (46%), Gaps = 6/118 (5%)
Query: 432 PRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQ 491
P G ++ P S G + E L QQ+ + QQ+QQQQQQ
Sbjct: 1198 PTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQ 1257
Query: 492 QQQQQQQQQQQQQQQHSNQTSNWSPLGPP---SSPYGAAFTAEKPNSPMMYPQAFNNQ 546
QQQQQQQQQQQQQQQ QT +SP PP +SP A P P PQ F Q
Sbjct: 1258 QQQQQQQQQQQQQQQQQQQTQAFSP--PPNVTASPSMDGLLA-GPTMPQAPPQQFPYQ 1312
Score = 62.0 bits (149), Expect = 3e-09
Identities = 132/544 (24%), Positives = 190/544 (34%), Gaps = 126/544 (23%)
Query: 369 VSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPG 428
VS+ SP + SS PP +S LP P S N S PN+ T
Sbjct: 856 VSLDSPVSVGSS--PPVKNISAFPMLPKQPMLGGNPRMMDSQENYG-SSMGGPNRNVTVT 912
Query: 429 QAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMS---PAEQLKQMAAQQQQRAKLMQQK 485
Q P G+ L N A + S + P D + P L R+ +
Sbjct: 913 QTPSS-GDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGA 971
Query: 486 QQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNN 545
+ QQQQQ Q + + P+G ++PYG A + + S +P +
Sbjct: 972 RPVLQQQQQMLQMRPGE------------IPMGMGANPYGQAAASNQLGS---WPDGMLS 1016
Query: 546 QNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNS-----LNKQHNILTYGNTKP 600
+ T N L +N ++ + P+NL S L++ H +L+ +
Sbjct: 1017 MEQV--------SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATG 1068
Query: 601 LTHFNADLSQRMTPPVANPNK--NPLMPYIQQQQQQQQQQQQ-----QQQQQQPPPPQLQ 653
L + L P + N + P Q Q+ Q+ Q Q PP Q
Sbjct: 1069 LEEIDRALG---IPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQ-- 1123
Query: 654 APRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHP---VGLPRTTGPMQSSVP-- 708
HL +MNQ P G HP + PRT P Q +
Sbjct: 1124 -GGFHLQGQSPSF-----NSMMNQMNQQGNFPLQGM--HPRANIMRPRTNTPKQLRMQLQ 1175
Query: 709 ----------------------PGSGG------MVSGASPAGPGFLGSQPQAAIMKQMLI 740
P +GG M+ + GFL +Q A +++L
Sbjct: 1176 QRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLS 1235
Query: 741 ----DQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQ-----SHLPR---------- 781
QR ++ QQ+QQ ++Q+QQQQQQQQ +QQ QQ S P
Sbjct: 1236 HHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGL 1295
Query: 782 ------QHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGP 835
PQ+ PY Q N G D A R + +M +SR+ GP
Sbjct: 1296 LAGPTMPQAPPQQFPY---QPNYGMGQQPDPAFGRVSSPPNAMMSSRM----------GP 1342
Query: 836 SQNP 839
SQNP
Sbjct: 1343 SQNP 1346
Score = 53.1 bits (126), Expect = 1e-06
Identities = 69/313 (22%), Positives = 104/313 (33%), Gaps = 72/313 (23%)
Query: 427 PGQAPPRPGNGYLL--NPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQ 484
P Q PP G +L +P+ ++ + P M P RA +M+
Sbjct: 1116 PAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHP-------------RANIMRP 1162
Query: 485 KQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFN 544
+ +Q + Q QQ+ Q QQ + ++ + + P++ A PMM PQ +
Sbjct: 1163 RTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMR------PMMQPQVSS 1216
Query: 545 NQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHF 604
Q + M + ++++ Q + M+ QQ
Sbjct: 1217 QQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQ--------------------------- 1249
Query: 605 NADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQK 664
QQQQQQQQQQQQQQQQQQ Q Q S
Sbjct: 1250 ------------------------QQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPN 1285
Query: 665 RLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPG 724
G++ P A P Q G+ + P V M+S
Sbjct: 1286 VTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQN 1345
Query: 725 FLGSQPQAAIMKQ 737
+ PQAA + Q
Sbjct: 1346 PMMQHPQAASIYQ 1358
Score = 40.4 bits (93), Expect = 0.010
Identities = 105/509 (20%), Positives = 168/509 (33%), Gaps = 110/509 (21%)
Query: 563 NNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTH---FNADLSQRMTPPVANP 619
NN + N ++ +Q GTNSL + + P ++ +S +PPV N
Sbjct: 814 NNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNI 873
Query: 620 NKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPM 679
+ P++P +Q P++ + + G N+ +
Sbjct: 874 SAFPMLP---------------KQPMLGGNPRMMDSQENYGSSM---------GGPNRNV 909
Query: 680 AYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQML 739
PS G P PM S+ GG + + P P GS P + +
Sbjct: 910 TVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPR-PALGGSIPTLPLRSNSI 968
Query: 740 IDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQF 799
R L QQQQQ+L Q++ +P + NPY +
Sbjct: 969 PGARPVL----------------QQQQQML---QMRPGEIP---MGMGANPYGQAAASNQ 1006
Query: 800 QGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTT 859
GS D + S + +R + +N+ +GP N + A + S T
Sbjct: 1007 LGSWPD--GMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNT 1064
Query: 860 PTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPA-SGQGVGMVSGFGQSMLVNS 918
+ + + G+ ++ + QA P+Q A GQ ++
Sbjct: 1065 DATGLEEIDRALGIPEL----------VNQGQALEPKQDAFQGQEAAVMMD--------- 1105
Query: 919 AITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFN 978
Q G GQ P Q PP +Q G LQG + + N
Sbjct: 1106 -------QKAGLYGQTYPA-QGPP--------MQGGFH------LQGQSPSFNSMMNQMN 1143
Query: 979 NGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQA 1038
++PLQ PR AN RT P + Q+ L GQQ +Q+
Sbjct: 1144 QQGNFPLQGMHPR----------------ANIMRPRTNTPKQLRMQLQQRLQGQQFLNQS 1187
Query: 1039 RPMVMSGLSQGVPGMPAFSQPPAQQQIPS 1067
R + + G A +P Q Q+ S
Sbjct: 1188 RQALELKMENPTAGGAAVMRPMMQPQVSS 1216
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 66.6 bits (161), Expect = 1e-10
Identities = 152/654 (23%), Positives = 217/654 (33%), Gaps = 147/654 (22%)
Query: 361 PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQT 420
P + P H S S A P+ P + + A S + S+ + + + P Q
Sbjct: 170 PGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVD 229
Query: 421 PNQAHTPGQAP--------PRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMA 472
+ + PG+AP P G L + AA + P A + L +M
Sbjct: 230 SLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMH 289
Query: 473 AQQQQRAKLMQQKQQQQQQQQ-------------------------------QQQQQQQQ 501
AQ Q+ QQ+ QQQQQQ QQ Q
Sbjct: 290 AQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQ 349
Query: 502 QQQQQHSNQTSNWSPLG--------PPSSPYGAAFTAEKPNS------PMMYPQAFNNQN 547
QQ Q Q P G PP+ P A P+ PM+ Q +
Sbjct: 350 QQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEY 409
Query: 548 PIVPPMANNLQKTTMNNYL----------PQN-------------HMNMINQQ----PNN 580
PI + L+ +M+ Y PQ +MN+ + P +
Sbjct: 410 PI-----HRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGS 464
Query: 581 LGTNSL----NKQHNILTYGNTKPLTHFNADLSQRMTPPVAN--PNKNPLM-------PY 627
G + HN + P + L TPPV + P+ PL
Sbjct: 465 AGVDRCASWNGSMHNGALDNHLSPSAY--PGLPGEFTPPVPDSFPSGPPLQHPAPDHQSL 522
Query: 628 IQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSH 687
QQQQQQQQQQQQQQQQQQ Q Q R Q L++KQ NQ P+
Sbjct: 523 QQQQQQQQQQQQQQQQQQQQQQQQQQQQR------QNAALMIKQMASRNQQQRLRQ-PNL 575
Query: 688 GQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAG---PGFLGSQPQAAIMKQMLIDQRA 744
Q HP + G GG+V G G P F + +Q+A
Sbjct: 576 AQLGHPGDV-------------GQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQA 622
Query: 745 QLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQ------HLQPQRNPYPVQQVNQ 798
+ Q+ F L +++ S LP L P P P
Sbjct: 623 PHLAQESAWF-----SGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPP--PPPGGSGVL 675
Query: 799 FQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGT-MATAAAQSEMGLAPYS 857
F+G Q+ + + + ++ + L + G+G Q+PG + +A SE P
Sbjct: 676 FRGPLQEPMRMPGEGHVPALPSPGLQF-GGSLGGLGQLQSPGAGVGLPSAASERRPPPPD 734
Query: 858 TTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFG 911
++ G G +G T + G P S G G SG G
Sbjct: 735 FATSALGGQPGFPFG---------AAGRQSTPHSGPGVNSPPSAGGGGGSSGGG 779
Score = 37.7 bits (86), Expect = 0.062
Identities = 23/51 (45%), Positives = 27/51 (52%), Gaps = 8/51 (15%)
Query: 24 SSLGG------AGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVP 68
S+LGG G +TP+S P S P+AGG GGS G GGG A P
Sbjct: 738 SALGGQPGFPFGAAGRQSTPHSGPGVNSP--PSAGGGGGSSGGGGGGGAYP 786
Score = 37.4 bits (85), Expect = 0.081
Identities = 130/567 (22%), Positives = 165/567 (29%), Gaps = 143/567 (25%)
Query: 620 NKNPLMPYIQQQQQQQQQQQQQQQ--------------------------------QQQP 647
+K P QQ QQQQQ QQQQQQ QQ P
Sbjct: 286 SKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAP 345
Query: 648 PPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHG----QEQHPVGLPRTTGPM 703
PPPQ Q P+ QP P G Q P LPR P
Sbjct: 346 PPPQQQPPQ--------------------QPPQQQPPPPPGLLVRQNSCPPALPR---PQ 382
Query: 704 QSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQ 763
Q SGG+ G GP ++ Q QF + +
Sbjct: 383 QGEAGTPSGGLQDG----GP----------------------MLPSQHAQFEYPIHRLEN 416
Query: 764 QQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQ-SMRTSR 822
+ +E H P Q P Q++ F P A R + S R
Sbjct: 417 RSMHPYSEPVFSMQHPPPQQA-------PNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDR 469
Query: 823 LMAQNAGMMG------IGPSQNPGTMA--TAAAQSEMGLAPYSTTPTSQPGMYNMSTGMT 874
+ N M + PS PG T P P
Sbjct: 470 CASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQ 529
Query: 875 QMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQ-HPQMKGPVGQ 933
Q Q Q Q Q RQ A+ M S Q L + Q HP G G
Sbjct: 530 QQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGL 589
Query: 934 ALPRPQ---APPRLQ--------SLMGTVQQGAQSWQQRSLQ-GMPGRTSGELGPFNNGA 981
P A P + +GT +Q A Q S P G+L P G
Sbjct: 590 VHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGG 649
Query: 982 SYPLQAGQPRLTKQHFPQGLSQSVVDANTGTV---RTLNPAAM-GRQMMPSLPG---QQG 1034
S G P H P L+ +G + P M G +P+LP Q G
Sbjct: 650 S-----GLPADCGPHDPS-LAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFG 703
Query: 1035 TSQAR--PMVMSGLSQGVPGMPAFSQPP----------AQQQIPSGSFAPSSQSQAYER- 1081
S + G G+P + +PP Q P G+ S +
Sbjct: 704 GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGV 763
Query: 1082 NAPQDVSY---NYSGDGAGGSFPGLPD 1105
N+P + G G GG++P PD
Sbjct: 764 NSPPSAGGGGGSSGGGGGGGAYPPQPD 790
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 66.2 bits (160), Expect = 2e-10
Identities = 62/201 (30%), Positives = 76/201 (37%), Gaps = 22/201 (10%)
Query: 361 PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPN-PASSPANCAVQSPQ 419
P SP S G PS G P S P P P P S P PQ
Sbjct: 108 PPQSPMDQHSQGYMSPHPSPLGAP-----EHVSSPMSGGGPTPPQMPPSQPGALIPGDPQ 162
Query: 420 TPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRA 479
+Q + G +P P + L + A G P + Q+A Q ++
Sbjct: 163 AMSQPNR-GPSPFSPVQLHQLRAQILAYKMLARG---------QPLPETLQLAVQGKRTL 212
Query: 480 KLMQQKQQQQQQQQQQQQQQQQQQQQ------QHSNQTSNWSPLGPPSSPYGAAFTAEKP 533
+QQ+QQQQQQQQQQQQQQQQQQQQ Q Q L + P G P
Sbjct: 213 PGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGP 272
Query: 534 NSPMMYPQAFNNQNPIVPPMA 554
++P P P P A
Sbjct: 273 STPQKLPVPAPGGRPSPAPPA 293
Score = 60.5 bits (145), Expect = 9e-09
Identities = 108/457 (23%), Positives = 160/457 (35%), Gaps = 84/457 (18%)
Query: 388 VSTATSLPSVASTPAAPNPASSPANCAVQSPQT-PNQAHTPGQAPPRPGNGYLLNPAAVT 446
+ST T ++ +P P SP SP P+ P PG + +P +
Sbjct: 1 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHP--MP 58
Query: 447 VAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQ 506
GS P P + + + M+ + Q Q Q
Sbjct: 59 TMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQ 118
Query: 507 HSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVP--PMANNLQKTTMNN 564
+ + SPLG P + + P P M P + ++P P A
Sbjct: 119 -GYMSPHPSPLGAPEH-VSSPMSGGGPTPPQMPP---SQPGALIPGDPQA---------- 163
Query: 565 YLPQNHMNMINQQPNNLGTNSLNK------QHNILTYGNTKPLTHFNADLSQRMTPPVAN 618
M+ N+ P+ L++ + +L G P T A +R P +
Sbjct: 164 ------MSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQ 217
Query: 619 PNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQP 678
QQQQQQQQQQQQQQQQQQ PQ Q P+ + Q QP
Sbjct: 218 ----------QQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQ-------------QP 254
Query: 679 MAYAALPSHGQEQHPVGLPRTTGPM--QSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMK 736
AL ++ + P P +GP Q P GG S A PA +QP AA +
Sbjct: 255 ----ALVNYNRPSGPG--PELSGPSTPQKLPVPAPGGRPSPAPPA-----AAQPPAAAVP 303
Query: 737 QMLIDQRAQ------LIEQQKQQFLRE-QRQQQQQQQQILAEQQLQQSHLPRQHLQPQRN 789
+ Q A L QQKQ + Q+ Q +IL E R++ R
Sbjct: 304 GPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQE---------REYRLQARI 354
Query: 790 PYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQ 826
+ +Q++ GS ++ L+++R Q
Sbjct: 355 AHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQ 391
Score = 44.7 bits (104), Expect = 5e-04
Identities = 59/228 (25%), Positives = 83/228 (36%), Gaps = 22/228 (9%)
Query: 646 QPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQS 705
+PP P + P++ + + + + + P ++ S G P P G +
Sbjct: 100 RPPHPGMGPPQSPMDQHSQGYM-SPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIP 158
Query: 706 SVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQML-----IDQRAQLIEQQKQQFLREQRQ 760
P G SP P L + +ML + + QL Q K+ Q+Q
Sbjct: 159 GDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQ 218
Query: 761 QQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAA---LQS 817
QQQQQQQ +QQ QQ Q QPQ+ P P Q Q Q P + R L
Sbjct: 219 QQQQQQQQQQQQQQQQ-----QQQQPQQQP-PQPQTQQ-QQQPALVNYNRPSGPGPELSG 271
Query: 818 MRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPG 865
T + + A P P AAAQ P + P PG
Sbjct: 272 PSTPQKLPVPA------PGGRPSPAPPAAAQPPAAAVPGPSVPQPAPG 313
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 66.2 bits (160), Expect = 2e-10
Identities = 62/201 (30%), Positives = 76/201 (37%), Gaps = 22/201 (10%)
Query: 361 PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPN-PASSPANCAVQSPQ 419
P SP S G PS G P S P P P P S P PQ
Sbjct: 108 PPQSPMDQHSQGYMSPHPSPLGAP-----EHVSSPMSGGGPTPPQMPPSQPGALIPGDPQ 162
Query: 420 TPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRA 479
+Q + G +P P + L + A G P + Q+A Q ++
Sbjct: 163 AMSQPNR-GPSPFSPVQLHQLRAQILAYKMLARG---------QPLPETLQLAVQGKRTL 212
Query: 480 KLMQQKQQQQQQQQQQQQQQQQQQQQ------QHSNQTSNWSPLGPPSSPYGAAFTAEKP 533
+QQ+QQQQQQQQQQQQQQQQQQQQ Q Q L + P G P
Sbjct: 213 PGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGP 272
Query: 534 NSPMMYPQAFNNQNPIVPPMA 554
++P P P P A
Sbjct: 273 STPQKLPVPAPGGRPSPAPPA 293
Score = 60.5 bits (145), Expect = 9e-09
Identities = 108/457 (23%), Positives = 160/457 (35%), Gaps = 84/457 (18%)
Query: 388 VSTATSLPSVASTPAAPNPASSPANCAVQSPQT-PNQAHTPGQAPPRPGNGYLLNPAAVT 446
+ST T ++ +P P SP SP P+ P PG + +P +
Sbjct: 1 MSTPTDPGAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHP--MP 58
Query: 447 VAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQ 506
GS P P + + + M+ + Q Q Q
Sbjct: 59 TMGSTDFPQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQ 118
Query: 507 HSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVP--PMANNLQKTTMNN 564
+ + SPLG P + + P P M P + ++P P A
Sbjct: 119 -GYMSPHPSPLGAPEH-VSSPMSGGGPTPPQMPP---SQPGALIPGDPQA---------- 163
Query: 565 YLPQNHMNMINQQPNNLGTNSLNK------QHNILTYGNTKPLTHFNADLSQRMTPPVAN 618
M+ N+ P+ L++ + +L G P T A +R P +
Sbjct: 164 ------MSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQ 217
Query: 619 PNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQP 678
QQQQQQQQQQQQQQQQQQ PQ Q P+ + Q QP
Sbjct: 218 ----------QQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQ-------------QP 254
Query: 679 MAYAALPSHGQEQHPVGLPRTTGPM--QSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMK 736
AL ++ + P P +GP Q P GG S A PA +QP AA +
Sbjct: 255 ----ALVNYNRPSGPG--PELSGPSTPQKLPVPAPGGRPSPAPPA-----AAQPPAAAVP 303
Query: 737 QMLIDQRAQ------LIEQQKQQFLRE-QRQQQQQQQQILAEQQLQQSHLPRQHLQPQRN 789
+ Q A L QQKQ + Q+ Q +IL E R++ R
Sbjct: 304 GPSVPQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQE---------REYRLQARI 354
Query: 790 PYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQ 826
+ +Q++ GS ++ L+++R Q
Sbjct: 355 AHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQ 391
Score = 44.7 bits (104), Expect = 5e-04
Identities = 59/228 (25%), Positives = 83/228 (36%), Gaps = 22/228 (9%)
Query: 646 QPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQS 705
+PP P + P++ + + + + + P ++ S G P P G +
Sbjct: 100 RPPHPGMGPPQSPMDQHSQGYM-SPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIP 158
Query: 706 SVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQML-----IDQRAQLIEQQKQQFLREQRQ 760
P G SP P L + +ML + + QL Q K+ Q+Q
Sbjct: 159 GDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQ 218
Query: 761 QQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAA---LQS 817
QQQQQQQ +QQ QQ Q QPQ+ P P Q Q Q P + R L
Sbjct: 219 QQQQQQQQQQQQQQQQ-----QQQQPQQQP-PQPQTQQ-QQQPALVNYNRPSGPGPELSG 271
Query: 818 MRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPG 865
T + + A P P AAAQ P + P PG
Sbjct: 272 PSTPQKLPVPA------PGGRPSPAPPAAAQPPAAAVPGPSVPQPAPG 313
>gi|162951884 R3H domain containing 2 [Homo sapiens]
Length = 976
Score = 66.2 bits (160), Expect = 2e-10
Identities = 117/498 (23%), Positives = 182/498 (36%), Gaps = 70/498 (14%)
Query: 449 GSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHS 508
G ++G ++ P + E Q+ + Q R L QQQQQQQQQQ QQQ
Sbjct: 367 GGSAGRISRPGMALGAPEVCNQVTSSQSVRGLLPCTAQQQQQQQQQQLPALPPTPQQQPP 426
Query: 509 NQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPP--------MANNLQKT 560
S S+P+G + + ++ P A Q P++ MA+ Q
Sbjct: 427 LNNHMISQADDLSNPFGQMSLSRQGSTEAADPSAALFQTPLISQHPQQTSFIMASTGQPL 486
Query: 561 TMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYG---------NTKPLTH---FNADL 608
+NY +H Q G +Q + Y +PL+H ++
Sbjct: 487 PTSNYSTSSHAPPTQQVLPPQGYMQPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSPQR 546
Query: 609 SQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLL 668
Q++ P P P+MP QQ Q QQ Q Q L Q+ +
Sbjct: 547 GQQLPQPSQQPGLQPMMPNQQQAAYQGMIGVQQPQNQG------------LLSSQRSSMG 594
Query: 669 MKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSV-PPGSGGMVSGASPAGPGFLG 727
+ +G++ Q Y LPS+ Q PVG Q+ V PP M+ P G
Sbjct: 595 GQMQGLVVQ---YTPLPSY---QVPVG-----SDSQNVVQPPFQQPMLV---PVSQSVQG 640
Query: 728 SQPQAAI-MKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQH--L 784
P A + + +I Q FL+ +Q Q Q + +P+Q+ +
Sbjct: 641 GLPAAGVPVYYSMIPPAQQNGTSPSVGFLQPPGSEQYQMPQ--SPSPCSPPQMPQQYSGV 698
Query: 785 QPQRNPYPVQQVNQFQGS--PQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTM 842
P V Q+N G PQ+ + V+ S + G P
Sbjct: 699 SPSGPGVVVMQLNVPNGPQPPQNPSMVQ---------WSHCKYYSMDQRGQKPGDLYSPD 749
Query: 843 ATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQ 902
++ A ++M +P T+PT P + T ++ + +G+S Q PR Q
Sbjct: 750 SSPQANTQMSSSPV-TSPTQSPAPSPV-TSLSSVC-----TGLSPLPVLTQFPRPGGPAQ 802
Query: 903 GVGMVSGFGQSMLVNSAI 920
G G S GQ + N +I
Sbjct: 803 GDGRYSLLGQPLQYNLSI 820
Score = 50.1 bits (118), Expect = 1e-05
Identities = 104/445 (23%), Positives = 155/445 (34%), Gaps = 70/445 (15%)
Query: 633 QQQQQQQQQQQQQQPPPPQLQAPRAH--LSEDQKRLLLMKQKGVMNQPMAYAALPSHGQE 690
QQQQQQQQQQ PP PQ Q P + +S+ Q + Q AA PS
Sbjct: 404 QQQQQQQQQQLPALPPTPQQQPPLNNHMISQADDLSNPFGQMSLSRQGSTEAADPSAALF 463
Query: 691 QHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQ 750
Q P+ + P Q+S M S P + A +Q+L Q QQ
Sbjct: 464 QTPL---ISQHPQQTSFI-----MASTGQPLPTSNYSTSSHAPPTQQVLPPQGYMQPPQQ 515
Query: 751 KQQFLREQRQQQQQQQQILAEQQLQQSHLPRQH---LQPQRNPYPVQQVNQFQGSPQDIA 807
Q Q QQ + P H PQR Q +
Sbjct: 516 IQVSYYPPGQYPNSNQQ----------YRPLSHPVAYSPQRG--------------QQLP 551
Query: 808 AVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMG------LAPYSTTPT 861
Q LQ M ++ A GM+G+ QN G + ++ +S MG + Y+ P+
Sbjct: 552 QPSQQPGLQPMMPNQQQAAYQGMIGVQQPQNQGLL--SSQRSSMGGQMQGLVVQYTPLPS 609
Query: 862 SQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGV--GMVSGFGQSMLVNSA 919
Q + + ++Q P Q M + +Q+ PA+G V M+ Q+ S
Sbjct: 610 YQ---VPVGSDSQNVVQPPFQQPMLVPVSQSVQGGLPAAGVPVYYSMIPPAQQNGTSPSV 666
Query: 920 ITQQHPQMKGPVGQALPRPQAPPRL-QSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFN 978
Q P + P P +PP++ Q G G PG +L
Sbjct: 667 GFLQPPGSEQYQMPQSPSPCSPPQMPQQYSGVSPSG------------PGVVVMQL---- 710
Query: 979 NGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQA 1038
N + P P + + + S G + + + + M S P T
Sbjct: 711 NVPNGPQPPQNPSMVQWSHCKYYSMDQRGQKPGDLYSPDSSPQANTQMSSSPVTSPTQSP 770
Query: 1039 RPMVMSGLSQ---GVPGMPAFSQPP 1060
P ++ LS G+ +P +Q P
Sbjct: 771 APSPVTSLSSVCTGLSPLPVLTQFP 795
Score = 48.9 bits (115), Expect = 3e-05
Identities = 91/346 (26%), Positives = 133/346 (38%), Gaps = 53/346 (15%)
Query: 758 QRQQQQQQQQILAEQQLQQSHLP-RQHLQPQ----RNPYPVQQVNQFQGSPQ--DIAAVR 810
Q+QQQQQQQQ+ A Q P H+ Q NP+ +++ QGS + D +A
Sbjct: 404 QQQQQQQQQQLPALPPTPQQQPPLNNHMISQADDLSNPFGQMSLSR-QGSTEAADPSAAL 462
Query: 811 SQAALQS---MRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEMGLAP--YSTTPTS--- 862
Q L S +TS +MA + P+ N T ++ A ++ L P Y P
Sbjct: 463 FQTPLISQHPQQTSFIMASTGQPL---PTSNYST-SSHAPPTQQVLPPQGYMQPPQQIQV 518
Query: 863 ---QPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSA 919
PG Y S + L HP + ++ +G + P Q G+ Q M+ N
Sbjct: 519 SYYPPGQYPNSNQQYRPLSHP------VAYSPQRGQQLPQPSQQPGL-----QPMMPN-- 565
Query: 920 ITQQHPQMKGPVGQALPRPQAPPRLQ-SLMGTVQQG--AQSWQQRSLQGMPGRTSGEL-- 974
QQ +G +G P+ Q Q S MG QG Q S Q G S +
Sbjct: 566 --QQQAAYQGMIGVQQPQNQGLLSSQRSSMGGQMQGLVVQYTPLPSYQVPVGSDSQNVVQ 623
Query: 975 GPFNNGASYP----LQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLP 1030
PF P +Q G P + + + + + +V L P + MP P
Sbjct: 624 PPFQQPMLVPVSQSVQGGLPAAGVPVYYSMIPPAQQNGTSPSVGFLQPPGSEQYQMPQSP 683
Query: 1031 GQQGTSQARPMVMSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQS 1076
Q P SG+S PG+ Q +P+G P + S
Sbjct: 684 SPCSPPQ-MPQQYSGVSPSGPGVVVM-----QLNVPNGPQPPQNPS 723
Score = 41.2 bits (95), Expect = 0.006
Identities = 52/217 (23%), Positives = 79/217 (36%), Gaps = 20/217 (9%)
Query: 344 PATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAA 403
P + PL+ S D S+ PF +S+ S Q ++ P + T P ++ P
Sbjct: 421 PQQQPPLNNHMISQADDLSN-PFGQMSL-SRQGSTEAADPSAALFQT----PLISQHPQQ 474
Query: 404 PNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMS 463
+ + + + +H P P GY+ P + V S P P+S+
Sbjct: 475 TSFIMASTGQPLPTSNYSTSSHAPPTQQVLPPQGYMQPPQQIQV--SYYPPGQYPNSNQQ 532
Query: 464 PAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ-----QQHSNQ---TSNWS 515
L A QR + + Q QQ Q QQQ Q QQ NQ +S S
Sbjct: 533 -YRPLSHPVAYSPQRGQQLPQPSQQPGLQPMMPNQQQAAYQGMIGVQQPQNQGLLSSQRS 591
Query: 516 PLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPP 552
+G +T P P ++QN + PP
Sbjct: 592 SMGGQMQGLVVQYT---PLPSYQVPVGSDSQNVVQPP 625
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 65.1 bits (157), Expect = 4e-10
Identities = 91/368 (24%), Positives = 137/368 (37%), Gaps = 58/368 (15%)
Query: 337 KEPEFSQPATETPL--SQESASVKSDPSHSPFAHVSMG-SPQARPSSSGPPFSTVSTATS 393
KE E+ PAT L QE +K A+ +G + Q + P ++ T+
Sbjct: 3062 KEKEYFDPATVRQLMAQQELDRIKK-------ANEVLGLAAQQQGMFDNTPLQALNLPTA 3114
Query: 394 LPSVASTPA-------APN-PASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAV 445
P++ P +P+ P +P+N A+ SP+ PN P P PG +
Sbjct: 3115 YPALQGIPPVLLPGLNSPSLPGFTPSNTALTSPK-PNLMGLPSTTVPSPG---------L 3164
Query: 446 TVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQ--------------- 490
+G + P + S +PA+ M QQ + + QQ+ Q QQ
Sbjct: 3165 PTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQPPPTPQL 3224
Query: 491 ---QQQQQQQQQQQQQQQQHSNQTSNWSPLGPPS-----SPYGAAFTAEKPNSPMMYP-- 540
QQQQ++ + ++ +++ PL P +P A T P M Y
Sbjct: 3225 PLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVD 3284
Query: 541 --QAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNT 598
Q Q + L + ++P Q P L + L + +
Sbjct: 3285 PAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPY 3344
Query: 599 KP-LTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQ--QQQQPPPPQLQAP 655
P L+ LS + L IQQQQQ+Q QQQQQQ QQQQP Q P
Sbjct: 3345 SPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVP 3404
Query: 656 RAHLSEDQ 663
S D+
Sbjct: 3405 PGAPSPDK 3412
Score = 62.4 bits (150), Expect = 2e-09
Identities = 98/435 (22%), Positives = 165/435 (37%), Gaps = 68/435 (15%)
Query: 386 STVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAV 445
S++S ++S PS ST + +S + A +P + + P ++ P G NP
Sbjct: 1643 SSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGMPPLG---NPIGA 1699
Query: 446 TVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQ 505
+A SP+E + A +++ A ++ +QQQQQQQQQQQQQQQQQQQ
Sbjct: 1700 NIA--------------SPSEPKE---ANRKKLADMIASRQQQQQQQQQQQQQQQQQQQA 1742
Query: 506 QHSNQTSNWSPLGPPSSPYGAAFTAE-KPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNN 564
Q L + A E + + ++ Q FN P + + TT
Sbjct: 1743 Q---------TLAQAQAQVQAHLQQELQQQAALIQSQLFN------PTLLPHFPMTTETL 1787
Query: 565 YLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPL 624
Q +++ LN + ++ LT L + + V P
Sbjct: 1788 LQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQ---- 1843
Query: 625 MPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAAL 684
Q QQ QQQQ Q L P H ++K L++K+K +Q +A
Sbjct: 1844 ----QSHQQILPQQQQNQLSIAQSHSALLQPSQH--PEKKNKLVIKEKEKESQRERDSAE 1897
Query: 685 PSHGQEQHPVGLP-RTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQR 743
G LP + + PG G S P + S + K +L +
Sbjct: 1898 GGEGNTGPKETLPDALKAKEKKELAPGGGSEPSMLPPR----IASDARGNATKALLENFG 1953
Query: 744 AQLIEQQKQQFLREQRQQQQQQQ-------------QILAEQQLQQSHLPRQHLQPQRNP 790
+L+ Q + + Q++ + Q ++ + + +SH H +N
Sbjct: 1954 FELVIQYNENKQKVQKKNGKTDQGENLEKLECDSCGKLFSNILILKSHQEHVH----QNY 2009
Query: 791 YPVQQVNQFQGSPQD 805
+P +Q+ +F +D
Sbjct: 2010 FPFKQLERFAKQYRD 2024
Score = 59.3 bits (142), Expect = 2e-08
Identities = 126/585 (21%), Positives = 198/585 (33%), Gaps = 91/585 (15%)
Query: 33 VNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCE 92
V+ + S+ A P S P A G G G G + T + L+ ++ +C
Sbjct: 2912 VDYSETSSLADPCSPSPGASGSAGKSGDSGDRPGQKRFRTQMTNLQLKVLK------SCF 2965
Query: 93 NRYQQAQVEQLELERRDTVSLYQRTLE-----QRAKKSGAGTGKQQHPSKPQQDAEAASA 147
N Y+ + + E+ D + L +R ++ RAK+ + +H Q E
Sbjct: 2966 NDYRTPTMLECEVLGND-IGLPKRVVQVWFQNARAKEKKSKLSMAKHFGINQTSYEGPKT 3024
Query: 148 E-------------QRNHTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIRK 194
E R+H I Q+ + + + S L+ +++ F P + R
Sbjct: 3025 ECTLCGIKYSARLSVRDH--IFSQQHISKVKDTIGSQLDKEKEY------FDPATVRQLM 3076
Query: 195 D------ISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNS-------GTHTPGLLE 241
I E + + +PL L+L + P G ++P L
Sbjct: 3077 AQQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPG 3136
Query: 242 DLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFSD 301
N L K + G L + L +P S SLS+ +
Sbjct: 3137 FTPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKP---------SSASLSSPTPAQAT 3187
Query: 302 INLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQP--ATETPLSQESASVKS 359
+ + Q+ P Q ++ P +QP + PL Q+
Sbjct: 3188 MAMGPQQ------------PPQQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDK 3235
Query: 360 DPS---HSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPA-NCAV 415
D AH G P P T + AT + + A +PA A A+
Sbjct: 3236 DSEKVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAAL 3295
Query: 416 QSPQTPN----------QAHTPGQAPPRPG---NGYLLNPAAVTVAGSASGPVAVPSSDM 462
S T +P AP PG +GYL + S ++ +
Sbjct: 3296 TSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGL 3355
Query: 463 SPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSS 522
SP L+Q QQ Q+ QQQQQ+Q QQQQQQ+ QQQ + P G PS
Sbjct: 3356 SPGSLLQQYQQYQQSL-----QEAIQQQQQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP 3410
Query: 523 PYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLP 567
A + KP P+ + P +P K+ + Y P
Sbjct: 3411 DKDPAKESPKPEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDP 3455
Score = 58.5 bits (140), Expect = 3e-08
Identities = 90/366 (24%), Positives = 132/366 (36%), Gaps = 71/366 (19%)
Query: 479 AKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMM 538
++L ++K+ +Q QQ+ + + +N+ LG + G P +
Sbjct: 3058 SQLDKEKEYFDPATVRQLMAQQELDRIKKANEV-----LGLAAQQQG--MFDNTPLQALN 3110
Query: 539 YPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNT 598
P A+ I P + L ++ + P N + + +PN +G S L
Sbjct: 3111 LPTAYPALQGIPPVLLPGLNSPSLPGFTPSNTA-LTSPKPNLMGLPSTTVPSPGLPTSGL 3169
Query: 599 KPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAP--- 655
P +A LS TP A P QQ QQQQQQQQ Q QQ PPPP Q P
Sbjct: 3170 -PNKPSSASLSSP-TPAQATMAMGP-----QQPPQQQQQQQQPQVQQPPPPPAAQPPPTP 3222
Query: 656 ----------------------RAHLSEDQKRLLLMKQKGVMNQPMAYAA-----LPSHG 688
+AH + + + K+KG P A AA LP+
Sbjct: 3223 QLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKG--EAPTATAATISAPLPTME 3280
Query: 689 QEQHPVGLPRTTGPMQSS---------------------VPPGSGGMVSGASPAGPGFLG 727
P L + S P G + SG G G
Sbjct: 3281 YAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEG 3340
Query: 728 SQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQHLQPQ 787
P + + Q L+ + QQ QQ+ + ++ QQQQQ +QQ QQ Q QP+
Sbjct: 3341 LFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQK---VQQQQPK 3397
Query: 788 RNPYPV 793
+ PV
Sbjct: 3398 ASQTPV 3403
Score = 35.8 bits (81), Expect = 0.24
Identities = 79/343 (23%), Positives = 131/343 (38%), Gaps = 79/343 (23%)
Query: 12 NGSSICINSSLNS--SLGGAGIGVNNTPNSTPAAPSSN-----HPAAGGCGGSGGPGGGS 64
N SSI ++SS S S G+ + P+S APSSN + G G P G +
Sbjct: 1641 NSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGMPPLGNPIGAN 1700
Query: 65 AAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQRAKK 124
A P S E R+++ + + QQ Q +Q + ++ T++ Q ++ ++
Sbjct: 1701 IASP--SEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQ 1758
Query: 125 SGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGACDGN 184
+ QQ A ++ N TL+ +
Sbjct: 1759 ------------ELQQQAALIQSQLFNPTLLP---------------------------H 1779
Query: 185 FSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHT-----PGL 239
F T++ + + ++ +L +PSA QL+ + SLP+ SG T PGL
Sbjct: 1780 FPMTTETLLQ-----LQQQQHLLFPFYIPSAE--FQLNPEVSLPV-TSGALTLTGTGPGL 1831
Query: 240 LEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLF 299
LEDL ++P+ ++ +I QS +P P +NKL
Sbjct: 1832 LEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHP----------EKKNKLV 1881
Query: 300 SDINLNDQEWQELIDEL----ANTVPEDDIQDLFNEDFEEKKE 338
I ++E Q D NT P++ + D +EKKE
Sbjct: 1882 --IKEKEKESQRERDSAEGGEGNTGPKETLPDALKA--KEKKE 1920
Score = 30.8 bits (68), Expect = 7.6
Identities = 37/133 (27%), Positives = 44/133 (33%), Gaps = 11/133 (8%)
Query: 933 QALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGASYP-LQAGQPR 991
QAL P A P LQ + + G S SL G + P N P P
Sbjct: 3107 QALNLPTAYPALQGIPPVLLPGLNS---PSLPGFTPSNTALTSPKPNLMGLPSTTVPSPG 3163
Query: 992 LTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMSGLSQGVP 1051
L P S + + + T PA M P P QQ Q +P V
Sbjct: 3164 LPTSGLPNKPSSASLSSPT-------PAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAA 3216
Query: 1052 GMPAFSQPPAQQQ 1064
P Q P QQQ
Sbjct: 3217 QPPPTPQLPLQQQ 3229
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,301,658
Number of Sequences: 37866
Number of extensions: 3144563
Number of successful extensions: 60496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 491
Number of HSP's successfully gapped in prelim test: 1203
Number of HSP's that attempted gapping in prelim test: 22543
Number of HSP's gapped (non-prelim): 18597
length of query: 1133
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1020
effective length of database: 13,968,660
effective search space: 14248033200
effective search space used: 14248033200
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.