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Search of human proteins with 38146107
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
(434 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 845 0.0
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 713 0.0
gi|38146109 arginine/serine-rich coiled-coil 2 isoform c [Homo s... 392 e-109
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 128 9e-30
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 124 2e-28
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 120 3e-27
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 119 4e-27
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 119 4e-27
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 118 9e-27
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 112 5e-25
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 112 9e-25
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 111 1e-24
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 111 1e-24
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 110 2e-24
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 110 3e-24
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 107 2e-23
gi|52426743 cisplatin resistance-associated overexpressed protei... 107 2e-23
gi|19923485 cisplatin resistance-associated overexpressed protei... 107 2e-23
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 106 5e-23
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 104 1e-22
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 104 1e-22
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 104 1e-22
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 104 2e-22
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 103 2e-22
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 103 4e-22
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 100 3e-21
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 100 3e-21
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 100 3e-21
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 100 3e-21
gi|50962882 G patch domain containing 8 [Homo sapiens] 96 6e-20
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 845 bits (2182), Expect = 0.0
Identities = 434/434 (100%), Positives = 434/434 (100%)
Query: 1 MAASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK 60
MAASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK
Sbjct: 1 MAASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK 60
Query: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS
Sbjct: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
Query: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS
Sbjct: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
Query: 181 RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALA 240
RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALA
Sbjct: 181 RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALA 240
Query: 241 RRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMA 300
RRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMA
Sbjct: 241 RRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMA 300
Query: 301 ALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFG 360
ALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFG
Sbjct: 301 ALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFG 360
Query: 361 NKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGM 420
NKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGM
Sbjct: 361 NKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGM 420
Query: 421 GLGFTSSMRGMDAV 434
GLGFTSSMRGMDAV
Sbjct: 421 GLGFTSSMRGMDAV 434
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 713 bits (1840), Expect = 0.0
Identities = 366/367 (99%), Positives = 367/367 (100%)
Query: 68 KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 127
K+GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
Query: 128 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 187
SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR
Sbjct: 69 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
Query: 188 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 247
HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK
Sbjct: 129 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 188
Query: 248 KLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKAL 307
KLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKAL
Sbjct: 189 KLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKAL 248
Query: 308 AETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFGNKDQNVK 367
AETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFGNKDQNVK
Sbjct: 249 AETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFGNKDQNVK 308
Query: 368 FRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGMGLGFTSS 427
FRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGMGLGFTSS
Sbjct: 309 FRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGMGLGFTSS 368
Query: 428 MRGMDAV 434
MRGMDAV
Sbjct: 369 MRGMDAV 375
Score = 45.8 bits (107), Expect = 8e-05
Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 39/156 (25%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
S R++KK +S R+ + SRSRSR R+ R+ RSRSRS+ RH ++
Sbjct: 88 SRSRERKKSRS------RSRERKKSRSRSRERK---------RRIRSRSRSRSRHRHRTR 132
Query: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RH 135
+S + +S DR KR E+ RS SR+ S R
Sbjct: 133 SRSRTRSRS-----------------------RDRKKRIEKPRRFSRSLSRTPSPPPFRG 169
Query: 136 RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRE 171
R+ + + +++ +R ER K RE++ + ++
Sbjct: 170 RNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQ 205
>gi|38146109 arginine/serine-rich coiled-coil 2 isoform c [Homo
sapiens]
Length = 202
Score = 392 bits (1007), Expect = e-109
Identities = 202/202 (100%), Positives = 202/202 (100%)
Query: 233 MDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQ 292
MDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQ
Sbjct: 1 MDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQ 60
Query: 293 IAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAE 352
IAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAE
Sbjct: 61 IAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAE 120
Query: 353 IWEKLNFGNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARS 412
IWEKLNFGNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARS
Sbjct: 121 IWEKLNFGNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARS 180
Query: 413 QTHTQRGMGLGFTSSMRGMDAV 434
QTHTQRGMGLGFTSSMRGMDAV
Sbjct: 181 QTHTQRGMGLGFTSSMRGMDAV 202
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 128 bits (322), Expect = 9e-30
Identities = 76/271 (28%), Positives = 136/271 (50%), Gaps = 19/271 (7%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRS--------RERKRKSDN 56
D + DG + D +K++E+ R ++ + + R R RER+R+ +N
Sbjct: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN 199
Query: 57 EGR-KHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK 115
+ +H R R +E R E++ ++ +K +++ D++ +++ RE+ E +R +
Sbjct: 200 KTEDRHSERGRERE-RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
Query: 116 ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRR 175
+++ R R R R R ++ R R +RK+ R R+R+ R R R+R++ R R R RKR
Sbjct: 259 DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRE 318
Query: 176 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDA 235
R R R R R R R R R + R R RK++ E R +R R GR A
Sbjct: 319 -RERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR-------EGRRQAERE 370
Query: 236 QEALARRLERAKKLQEQREKEM-VEKQKQQE 265
+E R ++ + +E+RE++ ++QK++E
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERE 401
Score = 125 bits (314), Expect = 7e-29
Identities = 77/279 (27%), Positives = 129/279 (46%), Gaps = 29/279 (10%)
Query: 15 KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHE 74
+T + D+K+E+ R H R R R +ER+R++D E + R + R+++ R
Sbjct: 70 QTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERER 129
Query: 75 SKDKSSKKHKSEE-----HNDKEHSSDKGRERLNSSENGE--DRHKRKERKSSRGRSHSR 127
++ ++ + + +++ ++K RER E +R+++KER+ + R R
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 128 SRSRER--------RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI-RS 178
R R+R RH R RER++ R E ++ R RER + R RER+++ R
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
Query: 179 RSRSRSRHRHRTRSRSRTRSRSRDRK-------------KRIEKPRRFSRSLSRTPSPPP 225
R+ R R + R R R R R RDR+ +R E+ R R R
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
Query: 226 FRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQ 264
R RN + + R ER ++ + REKE K+K+Q
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQ 348
Score = 125 bits (314), Expect = 7e-29
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 25/275 (9%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSR----SRSRERKRKSDNEGRK 60
+TER+G D +++E+ + R + R R +R +ER+R+ + + R+
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 61 HRSRSRSKEGR---RHESKDKSSKKHK-SEEHNDKEHSSDKGRERLNSSENGEDRHKRKE 116
R R R KE + RH + + ++ + +E +++ +D+ R+R +E ++ +E
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
Query: 117 RKSSRG------RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
R S R R R R R+R R + RER+ R R R ++ R R+R++ R R R
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
Query: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
ER+ R+R R R R R R R R R RDR+K E+ R+ + R R R
Sbjct: 310 ERE-----RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE------RNRQ 358
Query: 231 TAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
T + + R ER ++ Q +E E+++ ++
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRD 393
Score = 124 bits (312), Expect = 1e-28
Identities = 76/275 (27%), Positives = 133/275 (48%), Gaps = 17/275 (6%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
+ +RD + DR+++++ R + + R R R+R++++ E R H R
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR-HSER 208
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
R +E R E++ ++ +K +++ D++ +++ RE+ E +R ++++ R R
Sbjct: 209 GRERE-RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
Query: 125 HSRSRSRERRHRSRSRERKKSR--------SRSRERKKSRSRSRERKKSRSRSRERKRRI 176
R R R ++ R R +RK+ R R RER++ R R RER + R R RER+R
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE- 326
Query: 177 RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ 236
R R R R R + R R R R DR++ + R R R R R +A + +
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 237 E-ALARRLERAKKLQEQREKEM-----VEKQKQQE 265
E R +R K+ + Q EK+ EKQ+++E
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
Score = 124 bits (310), Expect = 2e-28
Identities = 78/274 (28%), Positives = 130/274 (47%), Gaps = 24/274 (8%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
+ ER+ E+ +R ++KE + H R R R RER+ +++ E ++ R
Sbjct: 178 EREREKNRQERRERERQREKEN-------KTEDRHSERGRERERERETETETERKRQTDR 230
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH---------KRK 115
R ++ + ++K +++ ++ E +E DK RER + DR +++
Sbjct: 231 ERDRQRKTEREREKQAERERASE---RETERDKERERERDRDRDRDRRQKERERQTDRKR 287
Query: 116 ERKSSRGRSHSRSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 174
+R++ R R R R R+R R R R R RK+ R R RER++ R R ER + + R R+RKR
Sbjct: 288 QRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
Query: 175 RI---RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 231
+ R R+R R R R R R R RDR+ E+ R R R R
Sbjct: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER-ERDRDRDRQKERERQTEK 406
Query: 232 AMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
D Q ++ ER K + +R +E ++++Q+
Sbjct: 407 DRDGQRETEKQREREKDRESERGRERGREREKQK 440
Score = 115 bits (288), Expect = 8e-26
Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 7/241 (2%)
Query: 19 DRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDK 78
+R++++E + R + R R RER+++++ E R R KE R +D+
Sbjct: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
Query: 79 SSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RHRS 137
+ + E +E +D+ R+R + +R + ++R+ R R +R R RER R R
Sbjct: 271 DRDRRQKE----RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 138 RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRHRTRSRSR- 195
R R+R+ R R +ER++ R R E + R+R R+ RR R R R R R R +R R
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 196 TRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREK 255
R R RDR ++ E+ R+ + R R +++ R ER K+ +R++
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDR 446
Query: 256 E 256
E
Sbjct: 447 E 447
Score = 112 bits (279), Expect = 9e-25
Identities = 73/246 (29%), Positives = 117/246 (47%), Gaps = 15/246 (6%)
Query: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR-KHR 62
+D ERD KT +R+K+ E+ RAS+ R + R RER R D + R K R
Sbjct: 228 TDRERD--RQRKTEREREKQAERE------RASERETERDKERERERDRDRDRDRRQKER 279
Query: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
R ++ +R +D+ +++ K E ++E ++ R+R E +R + ++R++ R
Sbjct: 280 ERQTDRKRQRRTERDRETER-KRERQRERERERERNRKR--ERERERERERERQRETERD 336
Query: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 182
R R R R +R RER + R R+ R R RER++ R +RER+ R R R R
Sbjct: 337 REKERERKR-KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 183 RSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 242
R + R R + R R ++++ EK R R R +GR D + R+
Sbjct: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRE--RDRERQTDRQ 453
Query: 243 LERAKK 248
R +K
Sbjct: 454 AGRQRK 459
Score = 108 bits (271), Expect = 7e-24
Identities = 68/233 (29%), Positives = 115/233 (49%), Gaps = 19/233 (8%)
Query: 42 RSRSRSRERKR-KSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRE 100
R+R + RER+R K E R R R +E RH +D+ ++ + E ++E +D+ R+
Sbjct: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDRE-KERERQTDRERD 114
Query: 101 RLNSSENG--EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKS--- 155
R E ++R + ER+ RGR RER R R E+++ R RER++
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERE-RQRDAEKERERQTDRERQRQTER 173
Query: 156 -RSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR--SRSRDRKKRIEKPRR 212
R + RER+K+R RER+R+ +++ RH R R R R R +RK++ ++ R
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 213 FSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
R R R + + A R ER K+ + +R+++ ++Q+E
Sbjct: 234 RQRKTERE--------REKQAERERASERETERDKERERERDRDRDRDRRQKE 278
Score = 102 bits (253), Expect = 9e-22
Identities = 65/231 (28%), Positives = 112/231 (48%), Gaps = 16/231 (6%)
Query: 5 DTERDGLAPEKTSPDRDK---KKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
+TERD + DRD+ +KE+ + R + R R RER+R+ + E ++
Sbjct: 255 ETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERN 314
Query: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDK-EHSSDKGRERLNSSENGEDRHKRKERKSS 120
R R R +E R + + +++ + +E K + ++ RER + + G + ++ ER+
Sbjct: 315 RKRERERERERERERQRETERDREKERERKRKRQTEMDRER--NRQTGREGRRQAERERE 372
Query: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER-KRRIRSR 179
R R R +RER R R R+ R R +ER++ + R+ ++ + RER K R R
Sbjct: 373 RERERDRQSAREREERERDRD----RDRQKERERQTEKDRDGQRETEKQREREKDRESER 428
Query: 180 SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
R R R R + + R R R R DR+ ++ R + +PPP R+
Sbjct: 429 GRERGREREKQKGRERDRERQTDRQAGRQRKRS-----TLYVNPPPRTARS 474
Score = 94.7 bits (234), Expect = 1e-19
Identities = 63/240 (26%), Positives = 116/240 (48%), Gaps = 26/240 (10%)
Query: 40 YSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGR 99
+SR R S+E R+ G+ H+ + R+ K++ ++ K + + + ++ R
Sbjct: 26 FSRRRPGSQESPRRR-GLGQAHKDAD-GDDRERNRQKERERRREKRQTERETDRKRERRR 83
Query: 100 ERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE---RRHRSRSRERKKSRSRSRERKKSR 156
E+ DRH++++R R R + R R+ R R R +ER + + R RE ++
Sbjct: 84 EK--------DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
Query: 157 SRSRERKKSRSRSRERKR---RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRF 213
R R+R+ R RER+R + R R R R R R+R + R R ++R++R E+ R+
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
Query: 214 SRSLSRTPSPPPFRGR--------NTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
+ ++T RGR T + + R +R +K + +REK+ E+++ E
Sbjct: 196 EKE-NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ-AERERASE 253
Score = 61.6 bits (148), Expect = 1e-09
Identities = 48/195 (24%), Positives = 79/195 (40%), Gaps = 8/195 (4%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH--- 61
+TERD + R + ++ + R + R R R RER R+S E +
Sbjct: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
Query: 62 RSRSRSKEGRRHESKDK-----SSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKE 116
R R R KE R KD+ + K+ + E+ + E ++GRER DR ++ +
Sbjct: 392 RDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTD 451
Query: 117 RKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI 176
R++ R R S +RS + +R + +S + K + +R +
Sbjct: 452 RQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAK 511
Query: 177 RSRSRSRSRHRHRTR 191
SR R R R R
Sbjct: 512 ASRGRVAGRRRWEPR 526
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 124 bits (311), Expect = 2e-28
Identities = 78/250 (31%), Positives = 130/250 (52%), Gaps = 7/250 (2%)
Query: 19 DRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDK 78
+R+K++++ E R + SRS R ER+R E + RSRSR ++G R + +
Sbjct: 296 EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRE 355
Query: 79 SSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSR 138
K+++ D+++ ++G ER E +R K + + + +RRHR
Sbjct: 356 REKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDD 415
Query: 139 SR----ERKKSRSRSRERK-KSRSRSRER-KKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192
R E+K SRSRSRERK +SRSRSR K+SRSRS+E+ + ++ S+ +S R R+ S
Sbjct: 416 KRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGS 475
Query: 193 RSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQ 252
+ RT S + +K+ + SR SR+ R + + D + RR ++ + QE
Sbjct: 476 QGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIE-QES 534
Query: 253 REKEMVEKQK 262
+EK+ K +
Sbjct: 535 QEKQHKNKDE 544
Score = 117 bits (294), Expect = 2e-26
Identities = 76/218 (34%), Positives = 122/218 (55%), Gaps = 20/218 (9%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEG-RKHRS 63
+ E++ E+ + +R+K++ +S S+ R + SRSR R R R R D +G R+ R
Sbjct: 296 EREKERQRLEREAKEREKERRRSR-SID-RGLERRRSRSRERHRSRSRSRDRKGDRRDRD 353
Query: 64 RSRSKEGRRHESKDKSSKKHK-SEEHNDKEHSSDKGRERLNSSENGEDRHKRKE------ 116
R R KE R +D+ K + +E ++E S ++ +E+ + E E +HK +
Sbjct: 354 REREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHR 413
Query: 117 ---RKSSRGRSHSRSRSRERRHRSRSRER---KKSRSRSRERK---KSRSRSRERKKSRS 167
R S + + HSRSRSRER+HRSRSR R K+SRSRS+E+ K+ S+ + K+SRS
Sbjct: 414 DDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRS 473
Query: 168 RSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205
S+ R + +S+ R + +SR R+RS+ R K+
Sbjct: 474 GSQGRTDSVE-KSKKREHSPSKEKSRKRSRSKERSHKR 510
Score = 114 bits (284), Expect = 2e-25
Identities = 93/289 (32%), Positives = 126/289 (43%), Gaps = 46/289 (15%)
Query: 15 KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHE 74
KT P + KK + R H R RSRS R R+ RSRS +EG
Sbjct: 234 KTRPRKIKKDGKEGAEEIDR----HVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSS 289
Query: 75 SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR--- 131
S D+ ++ K + ++E K RE+ DR + R SR R SRSRSR
Sbjct: 290 SFDRELEREKERQRLEREA---KEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRK 346
Query: 132 -ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSR----------- 179
+RR R R RE++ R R R+R + R ER+K R RSRER + RSR
Sbjct: 347 GDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKED 406
Query: 180 -------------------SRSRSRHR-HRTRSRSRT---RSRSRDRKKRIEKPRRFSRS 216
SRSRSR R HR+RSRSR RSRSR ++K K + S+
Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKS-SKHKNESKE 465
Query: 217 LSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
S S +GR +++ + + K + R KE K+ +
Sbjct: 466 KSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSD 514
Score = 111 bits (278), Expect = 1e-24
Identities = 82/288 (28%), Positives = 129/288 (44%), Gaps = 26/288 (9%)
Query: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
S + R L+P + SP R + + + R + R R + + E + RS
Sbjct: 260 SRSPRRSLSPRR-SPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRS 318
Query: 64 RS--RSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
RS R E RR S+++ + +S + D+ RE+ N DR KER + R
Sbjct: 319 RSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNER 378
Query: 122 GRSHSRSRSRERRHRSRS----RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIR 177
+ RSR R + RSR ++ K+ + R R R +E+K SRSRSRERK R R
Sbjct: 379 EKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSR 438
Query: 178 SRS-----RSRSRHRHRT---------RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSP 223
SRS RSRSR + ++ +S R+RS S+ R +EK ++ S S+ S
Sbjct: 439 SRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSR 498
Query: 224 PPFRGRNTA-----MDAQEALARRLERAKKLQEQREKEMVEKQKQQEI 266
R + + D+++ + R + EQ +E K K + +
Sbjct: 499 KRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDETV 546
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 120 bits (300), Expect = 3e-27
Identities = 81/256 (31%), Positives = 122/256 (47%), Gaps = 13/256 (5%)
Query: 11 LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSR------SRERKRKSDNEGRKHRSR 64
L +K R + +S R+ H +SRSR S + R G + RS+
Sbjct: 172 LVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS-----ENGEDRHKRKERKS 119
SRS+ R SK + S+ E+ + HS+ K R + +N ++ K K R
Sbjct: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
Query: 120 SRGRSHSRSRSRERRHRSRSRER-KKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS 178
SR +S S+SRSR + R +R SR RS+E+ +SRSR R K SRSR R R +S
Sbjct: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS-KS 350
Query: 179 RSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEA 238
+ + + R R R SRSR+RSRS+ + R +R S++ S R+ + +
Sbjct: 351 KDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410
Query: 239 LARRLERAKKLQEQRE 254
+++ E AK QRE
Sbjct: 411 VSKEREHAKSESSQRE 426
Score = 114 bits (286), Expect = 1e-25
Identities = 84/245 (34%), Positives = 122/245 (49%), Gaps = 36/245 (14%)
Query: 22 KKKEQSEVSVSPRASKHHYSRSRSRSR----ERKRKSDNEGR-----------KHRSRSR 66
K+K +S R+ H +SRS+S+ E+ + +DN G+ K +SRSR
Sbjct: 244 KEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR 303
Query: 67 SKEGRRHESKDKSSKKHKSEEHN---DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
S+E R E K S + +S+E + + S KG R S + + KRK RK SR
Sbjct: 304 SQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREE 363
Query: 124 SHSRSRSRERRHRSRSR-------------ERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
S SRSRSR + RSR R ++K+ RS+ R SRS S+ER+ ++S S
Sbjct: 364 SRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESS 423
Query: 171 ERKRRIRSRS-----RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPP 225
+R+ R S + +RSR R ++S+ S SR R K K R S+S SR+ S P
Sbjct: 424 QREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSP 483
Query: 226 FRGRN 230
R R+
Sbjct: 484 SRSRS 488
Score = 103 bits (257), Expect = 3e-22
Identities = 73/235 (31%), Positives = 118/235 (50%), Gaps = 32/235 (13%)
Query: 50 RKRKSDNEGRKH-RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENG 108
R+R+S + R H RSRSRS+ R+ S+ SSK HS + R R S
Sbjct: 180 RRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS---------SHSKSRSRSRSGS---- 226
Query: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
R S+ RS S+SRSR ++ +SRS ++KSRSRS KSRS+S+++ + + +
Sbjct: 227 --------RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ 278
Query: 169 SRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR--------IEKPRRFSRSLSRT 220
+ + + +SRS SRH+ +++SRSR++ R + +KR EK R SRS SR+
Sbjct: 279 NNDNVGK--PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336
Query: 221 PSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGS 275
R R+ + + R+ R + R + E+ +++ + G S
Sbjct: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
Score = 93.2 bits (230), Expect = 4e-19
Identities = 69/178 (38%), Positives = 89/178 (50%), Gaps = 19/178 (10%)
Query: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERK--RKSDNEGRKHRSRSRS------KEGR 71
++K QS + SRSRS+S++++ RK E + RSRSRS K G
Sbjct: 323 QEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGS 382
Query: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131
+ +SK SSKK K E+ D+ S R S + E H + E GR S +
Sbjct: 383 KRDSKAGSSKKKKKED-TDRSQSRSPSR-----SVSKEREHAKSESSQREGRGESENAGT 436
Query: 132 ERRHRSRSRERKKSR----SRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRS 184
+ RSRSR KS+ S SR R KS S++R R KSRSRS R R RSRS SRS
Sbjct: 437 NQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 85.1 bits (209), Expect = 1e-16
Identities = 61/165 (36%), Positives = 81/165 (49%), Gaps = 18/165 (10%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
S R + + +S+ R SRSRSRSR + +S G K S++ S + ++ E
Sbjct: 340 SRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT 399
Query: 77 DKSSKK------HKSEEHNDKEHSSDKGR-ERLNSSENGEDRHKRKERKSSRGRSHSRSR 129
D+S + K EH E S +GR E N+ N E R SR RS+S+S+
Sbjct: 400 DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETR--------SRSRSNSKSK 451
Query: 130 SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 174
S SR R KS S++R R KSRSRS R SRSRSR R
Sbjct: 452 P---NLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 46.6 bits (109), Expect = 4e-05
Identities = 41/134 (30%), Positives = 59/134 (44%), Gaps = 26/134 (19%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASK-----HHYSRSRSRSRERKRKSDNEG--R 59
+R K + KKKE ++ S S S+ +++S S RE + +S+N G +
Sbjct: 379 KRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQ 438
Query: 60 KHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 119
+ RSRSRS SK K + +S R R S+ R K + R +
Sbjct: 439 ETRSRSRS------NSKSKPNLPSES-------------RSRSKSASKTRSRSKSRSRSA 479
Query: 120 SRGRSHSRSRSRER 133
SR S SRSRS R
Sbjct: 480 SRSPSRSRSRSHSR 493
Score = 43.1 bits (100), Expect = 5e-04
Identities = 63/274 (22%), Positives = 107/274 (39%), Gaps = 26/274 (9%)
Query: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSR--SRTRSRSRDRKKRIEKPRRFSRSLSR 219
RK + RR RS SRSRS R R+RSR ++RSRS K K R SRS SR
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 220 TPSPPPFRGRNTAMD--------AQEALARRLERAKKLQEQREKEMVEK-QKQQEIAAAA 270
+ S R ++ + ++E R A K + + + + EK Q +
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 271 ATGGSVLNVAALLASGTQ---VTPQIAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMK 327
+ S + S +Q V + + Q K+L ++ S
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG-------- 339
Query: 328 FAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFGNKDQNVKFRKLMGIKSEDEAGCSSVDE 387
+ + + + K++G K E + +K + + R G K + +AG S +
Sbjct: 340 -SRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR---GSKRDSKAGSSKKKK 395
Query: 388 ESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGMG 421
+ Q R++ + E A+S++ + G G
Sbjct: 396 KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRG 429
Score = 35.8 bits (81), Expect = 0.078
Identities = 19/64 (29%), Positives = 30/64 (46%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
++E G E S R K + + R+ S++RSRS+ R R + + RSR
Sbjct: 430 ESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
Query: 65 SRSK 68
S S+
Sbjct: 490 SHSR 493
Score = 33.5 bits (75), Expect = 0.39
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 5 DTERD-GLAPEKT-SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
DT+R +P ++ S +R+ K +S S++ + +RSR R
Sbjct: 398 DTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSE 457
Query: 63 SRSRSKEGRRHESKDKSSKKHKS 85
SRSRSK + S+ KS + S
Sbjct: 458 SRSRSKSASKTRSRSKSRSRSAS 480
Score = 30.8 bits (68), Expect = 2.5
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
+ ++R+G + + + + +S + + + SRSRS+S + R R
Sbjct: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRS--------R 471
Query: 63 SRSRSKEGRRHESKDKSSKKHKS 85
S+SRS+ R S+ +S +S
Sbjct: 472 SKSRSRSASRSPSRSRSRSHSRS 494
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 119 bits (299), Expect = 4e-27
Identities = 78/249 (31%), Positives = 123/249 (49%), Gaps = 18/249 (7%)
Query: 17 SPDRDKKKEQSEV-SVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHES 75
S R K + S+ S R+ H SRS +RSR R++ H+ RS+S+E R+ S
Sbjct: 310 SHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS 369
Query: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-- 133
+ S K K KE K ++R E ++R K KER ++ R R + RE+
Sbjct: 370 RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 429
Query: 134 -RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR-----HR 187
+ R R RE++ + R +E++K + + +ER+K RS+ + KR+ +SR+ R R
Sbjct: 430 EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRR 489
Query: 188 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 247
R+ SR R R RSR + + R SR+PSP R RN + +R +
Sbjct: 490 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP---RSRN------KKDKKREKERD 540
Query: 248 KLQEQREKE 256
+ E+RE+E
Sbjct: 541 HISERRERE 549
Score = 111 bits (277), Expect = 1e-24
Identities = 70/201 (34%), Positives = 110/201 (54%), Gaps = 10/201 (4%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
S RDK+K+ E + + R + R RE++R+ + E K++ R + +E R + K
Sbjct: 371 SHSRDKRKDTRE-KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 429
Query: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR---KERKSSRGRSHSRSRSRER 133
+K ++ + +EH +K+ +K +E+ E +DR K K +K + R+ RS + R
Sbjct: 430 EKDREREREKEH-EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 488
Query: 134 RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS---RSRERKRRIRSRSRSR-SRHRHR 189
R RS SRER++ RSRS R S++ +RK SRS RSR +K + R + R S R R
Sbjct: 489 RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRER 548
Query: 190 TRSRS-RTRSRSRDRKKRIEK 209
RS S R S RD K+++EK
Sbjct: 549 ERSTSMRKSSNDRDGKEKLEK 569
Score = 110 bits (274), Expect = 3e-24
Identities = 72/267 (26%), Positives = 126/267 (47%), Gaps = 25/267 (9%)
Query: 13 PEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKE--- 69
PE T K+ E+ V R + S + E + ++ +G + RS +RSK
Sbjct: 264 PEMTPQAAAKELEE----VMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSS 319
Query: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129
+ H + +S KH+S HN S + ++R S + R K +ER+ SR RSHSR +
Sbjct: 320 SKSHSRRKRSQSKHRSRSHN---RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 376
Query: 130 SRERRH------------RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR-RI 176
++ R R + RER+K R + +ER K++ R +ER+K R + +E+ R R
Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 436
Query: 177 RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ 236
R + + R + + + + + + R +DR K I++ R+ + SRTP P + + +
Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTP-PRSYNASRRSRSSS 494
Query: 237 EALARRLERAKKLQEQREKEMVEKQKQ 263
RR R+ + K + K +
Sbjct: 495 RERRRRRSRSSSRSPRTSKTIKRKSSR 521
Score = 102 bits (254), Expect = 7e-22
Identities = 58/189 (30%), Positives = 101/189 (53%), Gaps = 10/189 (5%)
Query: 78 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RHR 136
+S K ++ + + H+ K R SS R KR + K R RSH+RSRSR++ R R
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSR----SSSKSHSRRKRSQSKH-RSRSHNRSRSRQKDRRR 350
Query: 137 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRT 196
S+S +K+S+SR R + +SRS SR+++K + K R++ + R + R R + R + +
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 410
Query: 197 RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 256
R +++DR K EK R + R R + D + + ++ K+ ++ R KE
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDRERE----REKEHEKDRDKEKEKEQDKEKEREKDRSKE 466
Query: 257 MVEKQKQQE 265
+ EK+K+ +
Sbjct: 467 IDEKRKKDK 475
Score = 97.4 bits (241), Expect = 2e-20
Identities = 69/257 (26%), Positives = 118/257 (45%), Gaps = 24/257 (9%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
D R +K S R+++K +S S K +R + + +ER ++ D E + R +
Sbjct: 347 DRRRSKSPHKKRSKSRERRKSRSR---SHSRDKRKDTREKIKEKERVKEKDREKEREREK 403
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
R KE R ++KD+ ++ K D+E +K RER E+ +DR K KE++ + +
Sbjct: 404 EREKEKERGKNKDRDKEREK-----DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 458
Query: 125 HSRSRSRERRHRSRSRERKKSRSRS-----RERKKSRSRSRERKKSRSRSRERKRRIRSR 179
+ RS+E + + ++ ++ RS R R SR R R R +S SRS + I+ +
Sbjct: 459 REKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 518
Query: 180 SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEAL 239
S SRS + + R + RD I + R RS S R + D +E L
Sbjct: 519 S-SRSPSPRSRNKKDKKREKERD---HISERRERERSTS-------MRKSSNDRDGKEKL 567
Query: 240 ARRLERAKKLQEQREKE 256
+ K+ + +E +
Sbjct: 568 EKNSTSLKEKEHNKEPD 584
Score = 60.5 bits (145), Expect = 3e-09
Identities = 52/203 (25%), Positives = 83/203 (40%), Gaps = 32/203 (15%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
+ E+D ++ +R+++KE + R +E++++ D E K R +
Sbjct: 420 EREKDREKDKEKDREREREKE----------------HEKDRDKEKEKEQDKE--KEREK 461
Query: 65 SRSKEGRRHESKDKSSK---KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
RSKE KDK S+ + + + S ++ R R SS K +RKSSR
Sbjct: 462 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSR 521
Query: 122 GRSHSRSRSRERRHRSRSRERKK-SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
S RSR ++ + R +ER S R RER S +S S R+ K ++ S
Sbjct: 522 SPS---PRSRNKKDKKREKERDHISERRERERSTSMRKS-------SNDRDGKEKLEKNS 571
Query: 181 RSRSRHRHRTRSRSRTRSRSRDR 203
S H S D+
Sbjct: 572 TSLKEKEHNKEPDSSVSKEVDDK 594
Score = 32.3 bits (72), Expect = 0.86
Identities = 17/82 (20%), Positives = 33/82 (40%)
Query: 15 KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHE 74
+ D+ ++KE+ +S + R S R+ K K + + + +KE
Sbjct: 528 RNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSV 587
Query: 75 SKDKSSKKHKSEEHNDKEHSSD 96
SK+ K E N +H+ +
Sbjct: 588 SKEVDDKDAPRTEENKIQHNGN 609
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 119 bits (299), Expect = 4e-27
Identities = 78/249 (31%), Positives = 123/249 (49%), Gaps = 18/249 (7%)
Query: 17 SPDRDKKKEQSEV-SVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHES 75
S R K + S+ S R+ H SRS +RSR R++ H+ RS+S+E R+ S
Sbjct: 194 SHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS 253
Query: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-- 133
+ S K K KE K ++R E ++R K KER ++ R R + RE+
Sbjct: 254 RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 313
Query: 134 -RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR-----HR 187
+ R R RE++ + R +E++K + + +ER+K RS+ + KR+ +SR+ R R
Sbjct: 314 EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRR 373
Query: 188 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAK 247
R+ SR R R RSR + + R SR+PSP R RN + +R +
Sbjct: 374 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP---RSRN------KKDKKREKERD 424
Query: 248 KLQEQREKE 256
+ E+RE+E
Sbjct: 425 HISERRERE 433
Score = 111 bits (277), Expect = 1e-24
Identities = 70/201 (34%), Positives = 110/201 (54%), Gaps = 10/201 (4%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
S RDK+K+ E + + R + R RE++R+ + E K++ R + +E R + K
Sbjct: 255 SHSRDKRKDTRE-KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 313
Query: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR---KERKSSRGRSHSRSRSRER 133
+K ++ + +EH +K+ +K +E+ E +DR K K +K + R+ RS + R
Sbjct: 314 EKDREREREKEH-EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 372
Query: 134 RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS---RSRERKRRIRSRSRSR-SRHRHR 189
R RS SRER++ RSRS R S++ +RK SRS RSR +K + R + R S R R
Sbjct: 373 RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRER 432
Query: 190 TRSRS-RTRSRSRDRKKRIEK 209
RS S R S RD K+++EK
Sbjct: 433 ERSTSMRKSSNDRDGKEKLEK 453
Score = 110 bits (274), Expect = 3e-24
Identities = 72/267 (26%), Positives = 126/267 (47%), Gaps = 25/267 (9%)
Query: 13 PEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKE--- 69
PE T K+ E+ V R + S + E + ++ +G + RS +RSK
Sbjct: 148 PEMTPQAAAKELEE----VMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSS 203
Query: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129
+ H + +S KH+S HN S + ++R S + R K +ER+ SR RSHSR +
Sbjct: 204 SKSHSRRKRSQSKHRSRSHN---RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 260
Query: 130 SRERRH------------RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR-RI 176
++ R R + RER+K R + +ER K++ R +ER+K R + +E+ R R
Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 320
Query: 177 RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ 236
R + + R + + + + + + R +DR K I++ R+ + SRTP P + + +
Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTP-PRSYNASRRSRSSS 378
Query: 237 EALARRLERAKKLQEQREKEMVEKQKQ 263
RR R+ + K + K +
Sbjct: 379 RERRRRRSRSSSRSPRTSKTIKRKSSR 405
Score = 102 bits (254), Expect = 7e-22
Identities = 58/189 (30%), Positives = 101/189 (53%), Gaps = 10/189 (5%)
Query: 78 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RHR 136
+S K ++ + + H+ K R SS R KR + K R RSH+RSRSR++ R R
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSR----SSSKSHSRRKRSQSKH-RSRSHNRSRSRQKDRRR 234
Query: 137 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRT 196
S+S +K+S+SR R + +SRS SR+++K + K R++ + R + R R + R + +
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 294
Query: 197 RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 256
R +++DR K EK R + R R + D + + ++ K+ ++ R KE
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDRERE----REKEHEKDRDKEKEKEQDKEKEREKDRSKE 350
Query: 257 MVEKQKQQE 265
+ EK+K+ +
Sbjct: 351 IDEKRKKDK 359
Score = 97.4 bits (241), Expect = 2e-20
Identities = 69/257 (26%), Positives = 118/257 (45%), Gaps = 24/257 (9%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
D R +K S R+++K +S S K +R + + +ER ++ D E + R +
Sbjct: 231 DRRRSKSPHKKRSKSRERRKSRSR---SHSRDKRKDTREKIKEKERVKEKDREKEREREK 287
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
R KE R ++KD+ ++ K D+E +K RER E+ +DR K KE++ + +
Sbjct: 288 EREKEKERGKNKDRDKEREK-----DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 342
Query: 125 HSRSRSRERRHRSRSRERKKSRSRS-----RERKKSRSRSRERKKSRSRSRERKRRIRSR 179
+ RS+E + + ++ ++ RS R R SR R R R +S SRS + I+ +
Sbjct: 343 REKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK 402
Query: 180 SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEAL 239
S SRS + + R + RD I + R RS S R + D +E L
Sbjct: 403 S-SRSPSPRSRNKKDKKREKERD---HISERRERERSTS-------MRKSSNDRDGKEKL 451
Query: 240 ARRLERAKKLQEQREKE 256
+ K+ + +E +
Sbjct: 452 EKNSTSLKEKEHNKEPD 468
Score = 60.5 bits (145), Expect = 3e-09
Identities = 52/203 (25%), Positives = 83/203 (40%), Gaps = 32/203 (15%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
+ E+D ++ +R+++KE + R +E++++ D E K R +
Sbjct: 304 EREKDREKDKEKDREREREKE----------------HEKDRDKEKEKEQDKE--KEREK 345
Query: 65 SRSKEGRRHESKDKSSK---KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
RSKE KDK S+ + + + S ++ R R SS K +RKSSR
Sbjct: 346 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSR 405
Query: 122 GRSHSRSRSRERRHRSRSRERKK-SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
S RSR ++ + R +ER S R RER S +S S R+ K ++ S
Sbjct: 406 SPS---PRSRNKKDKKREKERDHISERRERERSTSMRKS-------SNDRDGKEKLEKNS 455
Query: 181 RSRSRHRHRTRSRSRTRSRSRDR 203
S H S D+
Sbjct: 456 TSLKEKEHNKEPDSSVSKEVDDK 478
Score = 32.3 bits (72), Expect = 0.86
Identities = 17/82 (20%), Positives = 33/82 (40%)
Query: 15 KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHE 74
+ D+ ++KE+ +S + R S R+ K K + + + +KE
Sbjct: 412 RNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSV 471
Query: 75 SKDKSSKKHKSEEHNDKEHSSD 96
SK+ K E N +H+ +
Sbjct: 472 SKEVDDKDAPRTEENKIQHNGN 493
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 118 bits (296), Expect = 9e-27
Identities = 73/226 (32%), Positives = 115/226 (50%), Gaps = 11/226 (4%)
Query: 41 SRSRSRSRERKRKSDNE-GRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSD--K 97
SR S+ R+ +K + E G+K + R ++ RR +++ ++ + E ++E + K
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337
Query: 98 GRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRS 157
+ER E DR + KER R R R R RE RS +R K RSRSRE+ + R
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRE-----RSSDRNKDRSRSREKSRDRE 392
Query: 158 RSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSL 217
R RER++ R R RER+R R R R R R R R R + + R R D + E+ R+ R L
Sbjct: 393 RERERERERERERERERE-REREREREREREREREKDKKRDREEDEEDAYER-RKLERKL 450
Query: 218 SRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 263
+ R +N + + R E+ + +E+R +EM ++ K+
Sbjct: 451 REKEAAYQERLKNWEI-RERKKTREYEKEAEREEERRREMAKEAKR 495
Score = 113 bits (283), Expect = 3e-25
Identities = 76/270 (28%), Positives = 135/270 (50%), Gaps = 39/270 (14%)
Query: 22 KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSK 81
K+KE+ E+ K R R R RER+R+ + E + R R R KE R +++
Sbjct: 298 KEKERQEIE------KERRERERERERERERR-EREREREREREREKEKERERERERDRD 350
Query: 82 KHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RHRSRS 139
+ +++E + D++ D+ R+R SS+ +DR + +E+ R R R R RER R R R
Sbjct: 351 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERE 410
Query: 140 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR-----TRSRS 194
RER++ R R RER++ + + R+R++ + ER++ R + ++ R R R
Sbjct: 411 REREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 470
Query: 195 RTRSRSRDRKKRIEKPRRFSRSLSR-----------TPSPPPFRGRNTAMDAQEALARRL 243
+TR ++ ++ E+ R ++ R P +RG AL +RL
Sbjct: 471 KTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG--------SALQKRL 522
Query: 244 -ERAKKLQ-----EQREKEMVEKQKQQEIA 267
+R K+++ +REKE +E+ +Q+ +A
Sbjct: 523 RDREKEMEADERDRKREKEELEEIRQRLLA 552
Score = 100 bits (250), Expect = 2e-21
Identities = 70/264 (26%), Positives = 121/264 (45%), Gaps = 18/264 (6%)
Query: 19 DRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHE---- 74
D + K+ + + YS S ++SD+ RK + + RR
Sbjct: 197 DEETKRRDQMIKGAIEVLIREYS---SELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPL 253
Query: 75 ------SKDKSSKKHKSEEHND---KEHSSDKGRERLNSSENGEDRHKRKE-RKSSRGRS 124
+K+ + E+ D +E S + + E G+ +R+E K R R
Sbjct: 254 IPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERE 313
Query: 125 HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 184
R R RERR R R RER++ R + +ER++ R R R+R +++ R R+R R R R R R
Sbjct: 314 RERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRE-RDRDRDRE 372
Query: 185 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLE 244
R R + RSR+R +SRDR++ E+ R R R R R + + ++ +
Sbjct: 373 RSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRD 432
Query: 245 RAKKLQEQREKEMVEKQKQQEIAA 268
R + ++ E+ +E++ +++ AA
Sbjct: 433 REEDEEDAYERRKLERKLREKEAA 456
Score = 58.9 bits (141), Expect = 9e-09
Identities = 58/263 (22%), Positives = 104/263 (39%), Gaps = 41/263 (15%)
Query: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
+SD +D + S DR++++E+ R + R R R RER+R+
Sbjct: 374 SSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERE--------- 424
Query: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
R + K+ R E ++ + ++ K E K +E++++
Sbjct: 425 -REKDKKRDREEDEEDAYERRKLE-------------------------RKLREKEAA-- 456
Query: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 182
R ++ E R R ++RE +K R ER++ ++ +R K + R R
Sbjct: 457 -YQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG 515
Query: 183 RSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 242
+ + + RDRK+ E+ + L P P QEA RR
Sbjct: 516 SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDP--DAELQRMEQEAERRR 573
Query: 243 LERAKKLQEQREKEMVEKQKQQE 265
+ K+ E E+E EKQ+++E
Sbjct: 574 QPQIKQEPESEEEE-EEKQEKEE 595
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 112 bits (281), Expect = 5e-25
Identities = 95/312 (30%), Positives = 152/312 (48%), Gaps = 64/312 (20%)
Query: 1 MAASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK 60
M S ER + +K+ + K+ ++S V V R H R+ S S RK + + + +
Sbjct: 372 MRVSSGER-WIKGDKSELNEIKENQRSPVRVKERKITDH--RNVSESPNRKNEKEKKVKD 428
Query: 61 HRSRSRSKEGRRHESKD-----------------KSSKKHKSEEHNDKEHSSDKGRERLN 103
H+S S+ ++ RR+ KD KS +K KS+E + K + +++ R R
Sbjct: 429 HKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSR 488
Query: 104 SSENGEDRHKRKERKS-SRGRSHSRSRSRERRHRSRSRERKKSRSRSRER-KKSRSRSRE 161
S + K KE++S S+G+ RSRS+E+ + S+ + S+S+E+ ++++SRSRE
Sbjct: 489 SKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRE 548
Query: 162 ------------RKKSRSRSRERKRRIRSRSRSRSR-------------HRHRTRSRSRT 196
R + RSRSR+R RR+RSR+ R R +R R RSRSR
Sbjct: 549 CDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRE 608
Query: 197 ------RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQ 250
RSRS+DR++R RR SRS R S R ++ + + + R E +
Sbjct: 609 RRTPPGRSRSKDRRRR----RRDSRSSEREESQS--RNKDKYRNQESKSSHRKENS---- 658
Query: 251 EQREKEMVEKQK 262
+ EK M K +
Sbjct: 659 -ESEKRMYSKSR 669
Score = 105 bits (263), Expect = 6e-23
Identities = 94/279 (33%), Positives = 140/279 (50%), Gaps = 30/279 (10%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRS-RSRSRERKRKSDNEGRKHR- 62
D ++ + S R K KE+S+ R SKH+ + R RSR + R +N K +
Sbjct: 446 DKYKNKVKKRAKSKSRSKSKEKSKSK--ERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQ 503
Query: 63 SRSRSKEGRRHESKDKSSK-KHKSEEHNDKEHSSDKGRERLNSSENGE-DRHKRKERKSS 120
S S+ K+ R SK+KS + + KS EH +HS K ++R S + E D K K +S
Sbjct: 504 SDSKGKDQERSRSKEKSKQLESKSNEH---DHSKSKEKDRRAQSRSRECDITKGKHSYNS 560
Query: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRE---------RKKSRSRSRERKKSRSRSRE 171
R R RSRSR+R R RSR + RSRS+E R++ RSRSRER+ RSR
Sbjct: 561 RTRE--RSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRS 618
Query: 172 RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 231
+ RR R R SRS R ++SR++ + R+++ K K S + S R N+
Sbjct: 619 KDRR-RRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKS----RDHNS 673
Query: 232 AMDAQEALARR----LERAKKLQEQRE-KEMVEKQKQQE 265
+ +++E A R + K+ + E K + K K+ E
Sbjct: 674 SNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDE 712
Score = 80.9 bits (198), Expect = 2e-15
Identities = 93/418 (22%), Positives = 176/418 (42%), Gaps = 69/418 (16%)
Query: 31 VSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHND 90
+ R + + + SRSRSR+R R+S+ + R++ R S ++ K KSE +
Sbjct: 333 IKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQR-MRVSSGERWIKGDKSELNEI 391
Query: 91 KEHSSDKGR---ERLNSSENGEDRHKRKERKSSRGRSH-SRSRSRERRHRS------RSR 140
KE+ R ++ N + RK K + + H S S+ R+ R S +++
Sbjct: 392 KENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNK 451
Query: 141 ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR-----------SRSRHRHR 189
+K+++S+SR + K +S+S+ER +R+ E++ R RS+ R S S+ + +
Sbjct: 452 VKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQ 511
Query: 190 TRSRSR-------TRSRSRDRKKRIEKPRRF---SRSLSRTPSPPPFRGRNTAMDAQEAL 239
RSRS+ ++S D K EK RR SR T + R
Sbjct: 512 ERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDR 571
Query: 240 ARRL---------ERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVT 290
+RR+ R+K+ RE+E + + + G S + +
Sbjct: 572 SRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRS-------RSKDRRRR 624
Query: 291 PQIAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGK-------- 342
+ + +++ Q++ Y N + + + E +++M + +
Sbjct: 625 RRDSRSSEREESQSR-------NKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNS 677
Query: 343 --KEGDKSQSAEIWEKLNFGNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEE 398
K+ D+ QS + K+ ++D +K L EDE SSV++E+ K+ Q+ +
Sbjct: 678 REKKADRDQSP--FSKIKQSSQDNELKSSMLK--NKEDEKIRSSVEKENQKSKGQEND 731
Score = 69.3 bits (168), Expect = 6e-12
Identities = 62/220 (28%), Positives = 98/220 (44%), Gaps = 27/220 (12%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHY-SRSRSRSRERKRKSDNEGRKH-RSRSRSKEGRRHE 74
S ++D++ + KH Y SR+R RSR R R R H R RSRSKE R+
Sbjct: 535 SKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYR 594
Query: 75 SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR 134
++ + +E + GR R R +R R S R S SR++ + R
Sbjct: 595 EQEYRRRGRS----RSRERRTPPGRSRSKDRR----RRRRDSRSSEREESQSRNKDKYRN 646
Query: 135 HRSRSRERKKSRSRSRERKKSRSR-------SRERKKSRSRSRERKRRIRSR------SR 181
S+S RK++ S S +R S+SR SRE+K R +S K + S+ S
Sbjct: 647 QESKSSHRKEN-SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSM 705
Query: 182 SRSRHRHRTRS---RSRTRSRSRDRKKRIEKPRRFSRSLS 218
+++ + RS + +S+ ++ EK ++F S
Sbjct: 706 LKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESS 745
Score = 68.9 bits (167), Expect = 8e-12
Identities = 69/332 (20%), Positives = 130/332 (39%), Gaps = 73/332 (21%)
Query: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
++S ++ D + ++S D + +E R KH + + + ++KRK +
Sbjct: 198 SSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASS 257
Query: 62 RSRSRSKEGRRHES---------------KDKSSKKHKSEEHNDKEHSSDKGRERLNSSE 106
S + + E + + KS K +E ++E ++ NS
Sbjct: 258 ESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQP 317
Query: 107 NGEDR--------HKRKERKSSRGRSHSRSRSRERRHRSRS------------------- 139
R K K R R R+ SRSRSR+R RS +
Sbjct: 318 ASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSG 377
Query: 140 --------------RERKKSRSRSRERK--------KSRSRSRERKKS----RSRSRERK 173
+E ++S R +ERK +S +R E++K +S S+ER
Sbjct: 378 ERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERD 437
Query: 174 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAM 233
R S + +++ + R++S++RS+S+++ K E+ + +R+ + R R+
Sbjct: 438 IRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKR-----MRSRSKGR 492
Query: 234 DAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
D + + + K ++Q EK KQ E
Sbjct: 493 DHENVKEKEKQSDSKGKDQERSRSKEKSKQLE 524
Score = 66.2 bits (160), Expect = 5e-11
Identities = 62/210 (29%), Positives = 98/210 (46%), Gaps = 22/210 (10%)
Query: 11 LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR-KHRSRSRSKE 69
L P+ +KK+ +S S S +S S S S S+ SD+E + +S+ R K+
Sbjct: 177 LIPKSKVKKEEKKRHKSSSSSSSSSSD---SDSSSDSQSSSDSSDSESATEEKSKKRKKK 233
Query: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR----KERKSSRGRSH 125
R++ K K KK + + + K SS+ E L + R + E + +S
Sbjct: 234 HRKNSRKHKKEKKKRKK--SKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSP 291
Query: 126 SRSRSRERRHRSRSRERK----KSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR 181
++ +ER++R R RER+ S+ S +R+ +RS + K R RR R+ SR
Sbjct: 292 PKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRG-----PRRYRTPSR 346
Query: 182 SRSRHRHRTRSRSRTRSRSRDRKKRIEKPR 211
SRSR R R RS T R +R ++ R
Sbjct: 347 SRSRDRFR---RSETPPHWRQEMQRAQRMR 373
Score = 64.7 bits (156), Expect = 2e-10
Identities = 51/218 (23%), Positives = 95/218 (43%), Gaps = 19/218 (8%)
Query: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79
R+ + ++++ + P A S + + +K + + K S S S S D
Sbjct: 152 REIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQ 211
Query: 80 SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRS 139
S S+ + E S K R++ + + + + ++K+RK S+ + S S + + +S
Sbjct: 212 SSSDSSDSESATEEKSKK-RKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQS 270
Query: 140 RERKKS-----RSRSRERKKSRSRSRERKKSRSRSRER-------------KRRIRSRSR 181
R + +R RK + +K+R R RER +R + +RS
Sbjct: 271 TVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSG 330
Query: 182 SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSR 219
+ + R R R+ +RSRSRDR +R E P + + + R
Sbjct: 331 RKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQR 368
Score = 37.7 bits (86), Expect = 0.021
Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 16/125 (12%)
Query: 14 EKTSPDRDKKKEQSEVSV----SPRASKHHYSRSR---SRSRERKRKSDNEG---RKHRS 63
E S ++DK + Q S + + K YS+SR S + R++K+D + K +
Sbjct: 635 ESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQ 694
Query: 64 RSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
S+ E + K+K +K +S +KE+ KG+E +++ +++K+ + +SS G
Sbjct: 695 SSQDNELKSSMLKNKEDEKIRSSV--EKENQKSKGQE----NDHVHEKNKKFDHESSPGT 748
Query: 124 SHSRS 128
+S
Sbjct: 749 DEDKS 753
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 112 bits (279), Expect = 9e-25
Identities = 75/172 (43%), Positives = 104/172 (60%), Gaps = 16/172 (9%)
Query: 109 EDRHKRKERKSSRGRSHSRSRSRERRH-RSRSRERKKSRSRSRERKKSRSRSRERKKSRS 167
E RH RK R +SRGRS SRSRSR RS+ + ++SRSR R+R++ RSRSR++++SRS
Sbjct: 4 ESRHYRK-RSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 168 RSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR---------IEKPRRFSRSLS 218
R R+R RR RSR R RSR R R+RSR R RSRSR R +R +K SRS
Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122
Query: 219 RT----PSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE-KEMVEKQKQQE 265
+T S + ++ D +E A ++ K +E R+ KE VEK ++++
Sbjct: 123 KTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQ 174
Score = 97.4 bits (241), Expect = 2e-20
Identities = 68/200 (34%), Positives = 103/200 (51%), Gaps = 28/200 (14%)
Query: 60 KHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 119
+ RS SR + G R S+ S K+ K +G +R + S DR +R+ER
Sbjct: 9 RKRSASRGRSGSRSRSRSPSDKRSK------------RGDDRRSRSR---DRDRRRERSR 53
Query: 120 SRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSR 179
SR + SRSR R+R RSRSRER RSRER+ RSRSR+R++SRSRSR R+ R S
Sbjct: 54 SRDKRRSRSRDRKRLRRSRSRER----DRSRERR--RSRSRDRRRSRSRSRGRRSRSSSP 107
Query: 180 SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEAL 239
+ +R+RS+ +T ++K+ +K + G +E +
Sbjct: 108 GNKSKKTENRSRSKEKTDGGESSKEKKKDKD-------DKEDEKEKDAGNFDQNKLEEEM 160
Query: 240 ARRLERAKKLQEQREKEMVE 259
+R ER +K +E++ K+ +E
Sbjct: 161 RKRKERVEKWREEQRKKAME 180
Score = 86.7 bits (213), Expect = 4e-17
Identities = 62/189 (32%), Positives = 91/189 (48%), Gaps = 23/189 (12%)
Query: 34 RASKHHYSRSRSRSRERKRKSDNEGRKHRSRS----RSKEG--RRHESKDKSSKKHKSEE 87
R S+H+ RS SR R G + RSRS RSK G RR S+D+ ++ +S
Sbjct: 3 RESRHYRKRSASRGRS--------GSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRS 54
Query: 88 HNDKEHSSDKGRERLNSSENGE-DRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSR 146
DK S + R+RL S + E DR + + R SR R SRSRSR RR RS S K +
Sbjct: 55 R-DKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKK 113
Query: 147 SRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 206
+ +R R K ++ E K + + ++ K + + +++ R RK+R
Sbjct: 114 TENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNF-------DQNKLEEEMRKRKER 166
Query: 207 IEKPRRFSR 215
+EK R R
Sbjct: 167 VEKWREEQR 175
Score = 79.0 bits (193), Expect = 8e-15
Identities = 51/186 (27%), Positives = 84/186 (45%), Gaps = 9/186 (4%)
Query: 34 RASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEH 93
R++ S SRSRSR K G RSRSR ++ RR S+ + ++ +S +
Sbjct: 11 RSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRR 70
Query: 94 SSDKGRERLNSSENGEDRHKRKERKSSRGRSH------SRSRSRERRHRSRSRERKKSRS 147
S + R+R R +R+ R SRGR ++S+ E +RSRS+E+
Sbjct: 71 SRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTE--NRSRSKEKTDGGE 128
Query: 148 RSRERKKSR-SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 206
S+E+KK + + E++K + K R R + R R + + KK
Sbjct: 129 SSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKE 188
Query: 207 IEKPRR 212
IE+ ++
Sbjct: 189 IEEMKQ 194
Score = 67.8 bits (164), Expect = 2e-11
Identities = 48/134 (35%), Positives = 67/134 (50%), Gaps = 14/134 (10%)
Query: 146 RSRSRERKKSRSRSRERKKSRSRSRERKRR-----IRSRSRSRSRHRHRTRSRSRTRSRS 200
R RK+S SR R +SRSRS KR RSRSR R R R R+RSR + RSRS
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 201 RDRK---------KRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQE 251
RDRK + + RR SRS R S RGR + + +++ E + +E
Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122
Query: 252 QREKEMVEKQKQQE 265
+ + K+K+++
Sbjct: 123 KTDGGESSKEKKKD 136
Score = 66.6 bits (161), Expect = 4e-11
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 10/157 (6%)
Query: 17 SPDRDKKKEQSEVSVSPRASKH-----HYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
S DRD+++E+S R+ SRSR R R R+R+ + RSRSRS+ GR
Sbjct: 42 SRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSR-GR 100
Query: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS---SRGRSHSRS 128
R S +K K+E + + +D G ++ +D+ KE+ + + +
Sbjct: 101 RSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEM 160
Query: 129 RSR-ERRHRSRSRERKKSRSRSRERKKSRSRSRERKK 164
R R ER + R +RKK+ E KK ++ KK
Sbjct: 161 RKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKK 197
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 111 bits (278), Expect = 1e-24
Identities = 68/221 (30%), Positives = 109/221 (49%), Gaps = 37/221 (16%)
Query: 46 RSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS 105
R RERKR++D R R R +E R ++ ++ + + H +++ +D+ +ER
Sbjct: 3 RQRERKRETDRGKETERERDRQRE--RENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 106 ENGEDRHKRKERKSSRGRSHSRSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKK 164
E DR +++ER++ R R R R+R R R RER K R R R+R+ R+R R RK
Sbjct: 61 ER--DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
Query: 165 SRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 224
R R ++ +R R R R R R R R R R R+RK+ ++ R
Sbjct: 119 GRERDKQTERE-------RDRERERQRQRERERQRQRERKRETDRER------------- 158
Query: 225 PFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
+ A R ER K+ +++R+KE EK+K+++
Sbjct: 159 ------------QRWAEREERKKERKKERKKERKEKKKEEK 187
Score = 104 bits (259), Expect = 2e-22
Identities = 58/208 (27%), Positives = 109/208 (52%), Gaps = 24/208 (11%)
Query: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
++T +RD+++E+ + + R ++H R R R RER R++D E + R + R ++ +R
Sbjct: 15 KETERERDRQRERE--NQTERENRH---RQRDRHRERDRQTDREKERERQKERDRQRQRE 69
Query: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
++ +++ + E + R+R E +DR + ++R++ R R +R RER
Sbjct: 70 RETERETERQR-------ERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
Query: 134 ---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 190
R R RER++ R R RER++ R R RE + R R ER+ R + R + R + R
Sbjct: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER--- 179
Query: 191 RSRSRTRSRSRDRKKRIEKPRRFSRSLS 218
+ + ++ K+R +K R++ +S
Sbjct: 180 ------KEKKKEEKRREDKKRKWGEGIS 201
Score = 84.0 bits (206), Expect = 2e-16
Identities = 53/170 (31%), Positives = 79/170 (46%), Gaps = 21/170 (12%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
ERD + +R K++++ + R R R RERKR++D E K R R R
Sbjct: 45 ERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRER 104
Query: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 126
+E R+ +++ GRER +E DR + ++R+ R R
Sbjct: 105 KRETDRNRERNRKG-----------------GRERDKQTERERDRERERQRQRERERQRQ 147
Query: 127 RSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRR 175
R R RE R R R ER++ R +ERKK R + R+ KK + RE K+R
Sbjct: 148 RERKRETDRERQRWAEREE---RKKERKKERKKERKEKKKEEKRREDKKR 194
Score = 53.1 bits (126), Expect = 5e-07
Identities = 39/160 (24%), Positives = 64/160 (40%), Gaps = 36/160 (22%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
+TER+ + R++K++ R + R+R R RK + + + R R
Sbjct: 71 ETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERER 130
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
R +E +R RER +R +++ERK R
Sbjct: 131 DRERERQRQ-------------------------RER--------ERQRQRERKRETDRE 157
Query: 125 HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKK 164
R RE R + R +ERKK R +E+KK R ++K+
Sbjct: 158 RQRWAEREERKKERKKERKKER---KEKKKEEKRREDKKR 194
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 3/118 (2%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
ER + DRD+++++ R K R + RER R+ + + ++ R R R
Sbjct: 87 ERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQR 146
Query: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
+E +R D+ ++ E KE ++ +ER + E R + K+RK G S
Sbjct: 147 QRERKR--ETDRERQRWAEREERKKERKKERKKER-KEKKKEEKRREDKKRKWGEGIS 201
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 111 bits (278), Expect = 1e-24
Identities = 100/296 (33%), Positives = 146/296 (49%), Gaps = 38/296 (12%)
Query: 30 SVSPRASKHHYSRS----RSRSRERKRKSDNEGRKHRSRSRSKEG----RRHESKDKSSK 81
S +P H SRS RSRS +R +S + R+ RSRS + G R + + +S
Sbjct: 497 SRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS 556
Query: 82 KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER------RH 135
+ H+ + + R R + G R + R+ SR R+ +R RSR R R
Sbjct: 557 ARRGRSHSRSPATRGRSRSR-TPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRS 615
Query: 136 RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS---RSRHRHRT-- 190
RSR+ R++SR+RS R++SRSRS R+ RSRSR RR RSRSR+ R R R RT
Sbjct: 616 RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPA 675
Query: 191 ----RSRSRT---RSRSRDRKKRIEKPR-----RFSRSLSRTPSPPPFRGRNTAMDAQEA 238
RSRSRT R RSR R R + R R RS SRTP RGR+ + ++
Sbjct: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR---RGRSGSSSERKN 732
Query: 239 LARRLERAKKLQEQRE--KEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQ 292
+R +R + E K + ++ + +++ + S L++ L SG+ P+
Sbjct: 733 KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSL-SGSSPCPK 787
Score = 103 bits (257), Expect = 3e-22
Identities = 87/259 (33%), Positives = 123/259 (47%), Gaps = 35/259 (13%)
Query: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHY------SRSRSRSRERKRKSDN 56
+S +E +P+ T R +P H S++RS R ++ KS +
Sbjct: 415 SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474
Query: 57 E--------------GRKHRSRSRSKEGRRH-ESKDKSSKKHKSEEHNDKEHSSD-KGR- 99
++ RSRSR+ R H S+ ++ +S + + S +GR
Sbjct: 475 HTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRS 534
Query: 100 ---ERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156
+R S + + + + R + RGRSHSRS + R RSR+ R + RSRSR + R
Sbjct: 535 RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPAR-RGRSRSRTPARRR 593
Query: 157 SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRS-----RDRKKRIEKPR 211
SRSR + RSRSR RR RSRSR+ +R R RTRS R RSRS R + R P
Sbjct: 594 SRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPA 653
Query: 212 RFSRSLSRTPSPPPFRGRN 230
R RS SRTP+ RGR+
Sbjct: 654 RRGRSRSRTPAR---RGRS 669
Score = 93.6 bits (231), Expect = 3e-19
Identities = 84/277 (30%), Positives = 121/277 (43%), Gaps = 23/277 (8%)
Query: 12 APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
+P++ R + ++ S S R + H +R R R R R+ RSRSR+ R
Sbjct: 536 SPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSR---TPARRGRSRSRTPARR 592
Query: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131
R S+ + ++ +S + S + R S R R+ R S R RSRSR
Sbjct: 593 RSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR--RRSRSRSPARRSGRSRSR 650
Query: 132 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTR 191
R RSR R +R R +SRSR+ R+ RSRSR RR RSRSR+ R R R+R
Sbjct: 651 TPARRGRSRSRTPAR-----RGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR 705
Query: 192 S---RSRTRSRSRDRKKRI------EKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 242
S R R+ SR+ R+ R + R S+ SR+ S P + + +L+
Sbjct: 706 SLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP 765
Query: 243 LERAKKLQEQRE----KEMVEKQKQQEIAAAAATGGS 275
+AK R KQK Q + +G S
Sbjct: 766 RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS 802
Score = 91.7 bits (226), Expect = 1e-18
Identities = 79/265 (29%), Positives = 112/265 (42%), Gaps = 22/265 (8%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERK----RKSDNEG---- 58
E+ + + S + K S SP RSRSRSR K R+ D G
Sbjct: 1737 EKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQS 1796
Query: 59 ---RKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK 115
R+ RSRSRS+ RR S H + + R R S R + +
Sbjct: 1797 TSRRRQRSRSRSRVTRRRRG---GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSR 1853
Query: 116 ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRR 175
R S SRSR+ HR R R ++ SR R +SR+ R++SRSR+ +RR
Sbjct: 1854 SRTSPAPWKRSRSRASPATHR---RSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR 1910
Query: 176 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRR-----FSRSLSRTPSPPPFRGRN 230
RSR+ SR R R+R+ TR RSR R + R +R SR+ +PP R R+
Sbjct: 1911 SRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRS 1970
Query: 231 TAMDAQEALARRLERAKKLQEQREK 255
+ + R R + +R +
Sbjct: 1971 RSRTSPITRRRSRSRTSPVTRRRSR 1995
Score = 91.3 bits (225), Expect = 2e-18
Identities = 96/348 (27%), Positives = 150/348 (43%), Gaps = 55/348 (15%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
+R G + + TS R + + +S V+ R ++SRS +R + S R+ R RSR
Sbjct: 1789 DRSG-SSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS----RRRRGRSR 1843
Query: 67 SKEGRRHESKDKSSK---KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
+ R S+ ++S K + H + R L S R + + R S R
Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS------RRRSRSRTSPVSR 1897
Query: 124 SHSRSRSRERRHRSRSRERKKSRSRSRER------KKSRSR---SRERKKSRS------R 168
SRSR+ R RSRSR SR RSR R ++SRSR +R R +SR+ R
Sbjct: 1898 RRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRR 1957
Query: 169 SRER-----KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFS--------R 215
SR R +RR RSR+ +R R R+R+ TR RSR R + + R S R
Sbjct: 1958 SRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRR 2017
Query: 216 SLSRTP--------SPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEK-----QK 262
S SRTP S P R + RR R++ + R K + + ++
Sbjct: 2018 SRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRR 2077
Query: 263 QQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKALAET 310
+ +++ S A SG++ P +++M+ +++ T
Sbjct: 2078 RSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPT 2125
Score = 89.4 bits (220), Expect = 6e-18
Identities = 86/242 (35%), Positives = 115/242 (47%), Gaps = 30/242 (12%)
Query: 13 PEKTSPDRDKK---------KEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR- 62
P + SP RD+ + S S P SR S S E + + G HR
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPG-SHRE 452
Query: 63 -SRSRSKEGRRH-ESKDKSSKKHKSEEHNDKEHS---SDKGRERLNS-SENGEDRHKRKE 116
S S + + R H +K S H + S + +GR R + ++ G R + +
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ 512
Query: 117 -RKSSRGRSHSRSRSRERRHRSRSRERKK-SRSRSRERK-KSRSRSRERKKSRS-----R 168
R+S + RSRS +RR RSRS +R SRSR+ +R+ +SRS R R SRS R
Sbjct: 513 WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGR 572
Query: 169 SRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRG 228
SR R R RSRSR+ R R+RSR+ TR RSR R P R RS SRTP+ R
Sbjct: 573 SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSR-----TPARRGRSRSRTPARRRSRT 627
Query: 229 RN 230
R+
Sbjct: 628 RS 629
Score = 89.4 bits (220), Expect = 6e-18
Identities = 74/249 (29%), Positives = 112/249 (44%), Gaps = 16/249 (6%)
Query: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKR-----KSDNEGRKHRSRSRSK 68
EKT R + + S S S R + SRSRSR R+R S + R+ SR+ S+
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQR---SRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR 1836
Query: 69 EGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 128
R +S+K + + R + R R+ SR R+ S
Sbjct: 1837 RRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVS 1896
Query: 129 RSRERRHRSRSRERKKSRSRSRERKKSRSRSR--ERKKSRSRSRERKRRIRSRSRSRSRH 186
R R R S +R R +SR+ R++SRSR+ R++SRSR+ +RR RSR+ +R
Sbjct: 1897 RRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRR 1956
Query: 187 RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERA 246
R R+R+ TR RSR R I + R SR+ + P R R+ + + R R
Sbjct: 1957 RSRSRTPPVTRRRSRSRTSPITRRR------SRSRTSPVTRRRSRSRTSPVTRRRSRSRT 2010
Query: 247 KKLQEQREK 255
+ +R +
Sbjct: 2011 SPVTRRRSR 2019
Score = 87.0 bits (214), Expect = 3e-17
Identities = 91/293 (31%), Positives = 132/293 (45%), Gaps = 53/293 (18%)
Query: 15 KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSR--------ERKRKSDNEGRKH----- 61
++SP+ +K S S S +S SR+ R R E KS + R+
Sbjct: 1692 RSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSP 1751
Query: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS- 120
R+++ S+ GR K + ++ +S +K ++ + R+R SS++ R +R +S
Sbjct: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR-RDRSGSSQSTSRRRQRSRSRSRV 1810
Query: 121 ----RGRS--HSRSRSRE-------RRHRSRSRERKKSRSRSRER------KKSRSRSRE 161
RG S HSRS +R+ RR R RSR SR RSR R K+SRSR+
Sbjct: 1811 TRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASP 1870
Query: 162 RKKSRSRSRE---RKRRIRSRSRSRSRHRHRTRS---RSRTRSR----SRDRKKRIEKPR 211
RSRSR +RR RSR+ SR R R+R+ R R+RSR SR R + P
Sbjct: 1871 ATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPV 1930
Query: 212 RFSRSLSRTP---------SPPPFRGRNTAMDAQEALARRLERAKKLQEQREK 255
RS SRTP +PP R R+ + R R + +R +
Sbjct: 1931 TRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSR 1983
Score = 86.7 bits (213), Expect = 4e-17
Identities = 82/279 (29%), Positives = 122/279 (43%), Gaps = 27/279 (9%)
Query: 9 DGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNE-------GRKH 61
+G + ++SP+ K + R+S ++SR+ R R +S E R+
Sbjct: 1650 EGSSSTESSPEHPPKSRTARRG--SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
Query: 62 RSRSRSKEGR-RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
RS S S E R R + + S S E +K SS R R SS + +R S
Sbjct: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSR--RRRSASSPRTKTTSRRGRSPSP 1765
Query: 121 RGRSHSRSRSRERRHRSRSRERK----KSRSRSRERKKSRSRSRERKK--------SRSR 168
+ R RSRSR RR ++R+ R+ S+S SR R++SRSRSR ++ SRS
Sbjct: 1766 KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP 1825
Query: 169 SRERKRRI---RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPP 225
+R+ R R R RSR+ R RSRSRT R + P RS SRTP
Sbjct: 1826 ARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISR 1885
Query: 226 FRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQ 264
R R+ +R + + + V +++ +
Sbjct: 1886 RRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR 1924
Score = 80.9 bits (198), Expect = 2e-15
Identities = 85/272 (31%), Positives = 122/272 (44%), Gaps = 28/272 (10%)
Query: 2 AASDTERDGLAPE-KTSPDRDKKKEQS-------EVSVSPRASKHHYSRSRSRSR----- 48
+ SD+ + AP + P R + S E S S +S H +SR+ R
Sbjct: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675
Query: 49 -ERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSEN 107
E K KS R+ SRS + R K + S++ +S + + S R R + S +
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTR----KARLSRRSRSASSSPETRSRTPPRHRRSPSVS 1731
Query: 108 G-EDRHKRKERKSSRGRSHSRSRSRERRHRSRS---RERKKSRSRSRERKKSRSRSRERK 163
E K + + R S R+++ RR RS S R ++SRSRSR K +R R+R
Sbjct: 1732 SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRS 1791
Query: 164 KSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSP 223
S S+S R+R+ RSRSRSR R R S +RS +R R RR R SRT P
Sbjct: 1792 GS-SQSTSRRRQ-RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRR--RGRSRT--P 1845
Query: 224 PPFRGRNTAMDAQEALARRLERAKKLQEQREK 255
P R R+ + + R RA +R +
Sbjct: 1846 PTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877
Score = 79.3 bits (194), Expect = 6e-15
Identities = 70/222 (31%), Positives = 101/222 (45%), Gaps = 27/222 (12%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR--KHRSRSRSKEGRRHE 74
+P R + + +S V R+ RSRSR R+ + R R RSRS+ R
Sbjct: 619 TPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRS 678
Query: 75 SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR 134
+ +S + +GR R + G R + R RGRSH SR+ +RR
Sbjct: 679 GRSRSRTPAR------------RGRSRSRTPRRGRSRSRSLVR---RGRSH--SRTPQRR 721
Query: 135 HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRS 194
RS S +K++SR+ +R+ + S E KKSR S RR RS S RS+ + R R
Sbjct: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISS----RRSRSLSSPRSKAKSRLSLRR 777
Query: 195 RTRSRSRDRKKRIEKPRRFSRSLSRTPS----PPPFRGRNTA 232
S K++ + P R SRS S P PP R R+++
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSS 819
Score = 77.4 bits (189), Expect = 2e-14
Identities = 74/254 (29%), Positives = 116/254 (45%), Gaps = 24/254 (9%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
SP R + + +S S R SRSR+ +R + +S R+ RSRSR+ R S+
Sbjct: 629 SPVRRRSRSRSPARRSGR------SRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSR 682
Query: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 136
++ + + + +GR R S H R ++ RGRS S S ER+++
Sbjct: 683 SRTPARRG----RSRSRTPRRGRSRSRSLVRRGRSHSRTPQR--RGRSGS---SSERKNK 733
Query: 137 SRSRERKKSRSRSRERKKS-----RSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTR 191
SR+ +R+ + S E KKS RSRS +S+++SR RR S S + + +T
Sbjct: 734 SRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTP 793
Query: 192 SRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQE 251
R R+RS S K + P R SRS S SPPP + T + + + K
Sbjct: 794 PR-RSRSGSSQPKAKSRTPPRRSRSSS---SPPPKQKSKTPSRQSHSSSSPHPKVKSGTP 849
Query: 252 QREKEMVEKQKQQE 265
R+ + Q ++
Sbjct: 850 PRQGSITSPQANEQ 863
Score = 69.7 bits (169), Expect = 5e-12
Identities = 78/263 (29%), Positives = 109/263 (41%), Gaps = 32/263 (12%)
Query: 8 RDGLAPE-----KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
R G +PE + SP R + EV PRA+ ++S S S + R
Sbjct: 1578 RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR--AQSGSDSSPEPKAPAPRALPRR 1635
Query: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
SRS S R S + SS S EH K ++ +G K K R R
Sbjct: 1636 SRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG-------SRSSPEPKTKSRTPPRR 1688
Query: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 182
RS SRS S E ++R R +S S S E + SR+ R R+ S E +S
Sbjct: 1689 RS-SRS-SPELTRKARLSRRSRSASSSPETR-SRTPPRHRRSPSVSSPE------PAEKS 1739
Query: 183 RSRHRHRTRSRSRTRSRSRDRKKRIEKPR--RFSRSLSRTPSPPPFRGRNTAMDAQEALA 240
RS R R+ S RT++ SR + KPR + SRS SR R R+ + +Q
Sbjct: 1740 RSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSR 1799
Query: 241 RRLERAKKLQEQREKEMVEKQKQ 263
RR Q R + V ++++
Sbjct: 1800 RR-------QRSRSRSRVTRRRR 1815
Score = 65.5 bits (158), Expect = 9e-11
Identities = 33/121 (27%), Positives = 59/121 (48%)
Query: 103 NSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRER 162
+SS + + K+K++K RGR S R R +S +++ +S S S++RK + +
Sbjct: 178 SSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSK 237
Query: 163 KKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 222
+KS+ + R+R R +SR HR + + + SR R + + R+PS
Sbjct: 238 RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPS 297
Query: 223 P 223
P
Sbjct: 298 P 298
Score = 64.7 bits (156), Expect = 2e-10
Identities = 70/218 (32%), Positives = 100/218 (45%), Gaps = 14/218 (6%)
Query: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRS-RSRSR---ERKRKSDNEGR 59
S R G + +T R + + ++ S+ RS RSRSR R R R
Sbjct: 639 SPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPR 698
Query: 60 KHRSRSRS--KEGRRH-ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS-ENGEDR-HKR 114
+ RSRSRS + GR H + + + S E +K +S + R R NSS E + R R
Sbjct: 699 RGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR-RSRSNSSPEMKKSRISSR 757
Query: 115 KERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 174
+ R S RS ++SR RR S S K +S++ R +SRS S + K ++SR R
Sbjct: 758 RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR-RSRSGSSQPK---AKSRTPPR 813
Query: 175 RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRR 212
R RS S + + +T SR S S K + P R
Sbjct: 814 RSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPR 851
Score = 62.0 bits (149), Expect = 1e-09
Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 26/235 (11%)
Query: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
SD+ DG + + R+ K+ E P + S SRS + ++K+K + R RS
Sbjct: 142 SDSYVDGSSFDPQRRAREAKQPAPEPP-KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRS 200
Query: 64 RSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
S S RR K KKH+SE + K R + S + + K K++K R R
Sbjct: 201 ESSSP--RRERKKSSKKKKHRSESESKK---------RKHRSPTPKSKRKSKDKKRKRSR 249
Query: 124 SHSRSRSRERRHRSRSRERKKS--RSRSRERKKSRSRSRERKKSRSRSRERKRR------ 175
S + + R HRS S + S SRSR R + RS S RR
Sbjct: 250 STTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAP 309
Query: 176 -----IRSRSRSRSRHRHRTRSRSRTRSRSRDRK-KRIEKPRRFSRSLSRTPSPP 224
S R S + S + +D+K K +P S P PP
Sbjct: 310 FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPP 364
Score = 56.6 bits (135), Expect = 4e-08
Identities = 67/271 (24%), Positives = 109/271 (40%), Gaps = 48/271 (17%)
Query: 8 RDGLAPEKTSPDRDKKKEQSEVSVSPRA-SKHHYSRSRSRSRERKRKSDNEG-RKHRSRS 65
R G + +T R + + ++ R+ S RS SR+ +R+ +S + RK++SR+
Sbjct: 677 RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT 736
Query: 66 RSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLN-------SSENGEDRHKRKERK 118
+ R + S + + S K + RL+ SS + + + R+
Sbjct: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRR 796
Query: 119 SSRGRSHSRSRSRE--RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI 176
S G S +++SR RR RS S K +S++ R+ S S S K +S + R+ I
Sbjct: 797 SRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ-SHSSSSPHPKVKSGTPPRQGSI 855
Query: 177 RS------------------------RSRSRSRHRHRTRSRSRTRSRSRDRK-------- 204
S +SR+ SRH S R +S + R+
Sbjct: 856 TSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSP 915
Query: 205 ----KRIEKPRRFSRSLSRTPSPPPFRGRNT 231
K I PR+ S S S +PSP R T
Sbjct: 916 QPKVKAIISPRQRSHSGSSSPSPSRVTSRTT 946
Score = 55.5 bits (132), Expect = 1e-07
Identities = 64/237 (27%), Positives = 105/237 (44%), Gaps = 25/237 (10%)
Query: 8 RDGLAPEKTSPDRDKKKEQSEVSVSPRA-----SKHHYSRSRS--RSRERKRKSDNEGRK 60
R G + +T R + + ++ S R+ ++ SRSR+ R R R R GR
Sbjct: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS 713
Query: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSEN---GEDRHKRKER 117
H SR+ + GR S ++ +K S+ + S + + R++S + R K K R
Sbjct: 714 H-SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
Query: 118 KSSRGRSHSRS------RSRERRHRSRS-RERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
S R RS S S +S+ RSRS + K++SR+ R +SRS S K +S++
Sbjct: 773 LSLR-RSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR-RSRSSSSPPPKQKSKTP 830
Query: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS-----LSRTPS 222
R+ S + + R S T ++ ++ ++ F S SRTPS
Sbjct: 831 SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPS 887
Score = 54.7 bits (130), Expect = 2e-07
Identities = 65/204 (31%), Positives = 86/204 (42%), Gaps = 24/204 (11%)
Query: 42 RSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRER 101
RSRS S + K KS R RSRS S + +SK S + H S + K S R+
Sbjct: 796 RSRSGSSQPKAKSRTPPR--RSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG 853
Query: 102 LNSSENGEDRHKRKERKS-----------SRGRS-HSRSRSRERRHRSRSRERKK-SRSR 148
+S ++ +R+S SR S HS S S R +S + R+ SRS
Sbjct: 854 SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSS 913
Query: 149 SRE---------RKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSR 199
S + R++S S S SR SR RR RS S + S + S
Sbjct: 914 SPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSS 973
Query: 200 SRDRKKRIEKPRRFSRSLSRTPSP 223
S D K + E P R S S S +P P
Sbjct: 974 SPDTKVKPETPPRQSHSGSISPYP 997
Score = 52.4 bits (124), Expect = 8e-07
Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 8/157 (5%)
Query: 80 SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRS 139
++ H+ E N+K++ ERL ++ D + + R+ + + S
Sbjct: 119 TETHQLAELNEKKN------ERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYS 172
Query: 140 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSR 199
R+ S SRS K+ + + ++ + RS S RR R +S + +HR + S+ R
Sbjct: 173 LVRESSSSRSPTPKQKKKKKKKDRGRRSESSS-PRRERKKSSKKKKHRSESESKKRKHRS 231
Query: 200 SRDRKKRIEKPRRFSRSLSRTPSPPPFRG-RNTAMDA 235
+ KR K ++ RS S TP+P R R+T+ D+
Sbjct: 232 PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268
Score = 52.0 bits (123), Expect = 1e-06
Identities = 65/268 (24%), Positives = 95/268 (35%), Gaps = 18/268 (6%)
Query: 6 TERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRS 65
+E D K P + + +S S R RS S + RS
Sbjct: 1478 SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537
Query: 66 RSKEGRRHESKDKSSKKHKSEEHND-----KEHSSDKGRERLNSSENGEDRHKRKERKSS 120
RS + + K +S + +SE + K + + R R SS + + + R+S
Sbjct: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSR 1597
Query: 121 RGRS-----HSRSRSRERRHRSRSRERK-------KSRSRSRERKKSRSRSRERKKSRSR 168
G S R+ R + S E K RSRS K R S E S
Sbjct: 1598 SGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTES 1657
Query: 169 SRERKRRIRSRSR-SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFR 227
S E + R+ R SRS +T+SR+ R RS + + R SR S P R
Sbjct: 1658 SPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETR 1717
Query: 228 GRNTAMDAQEALARRLERAKKLQEQREK 255
R + E A+K + R +
Sbjct: 1718 SRTPPRHRRSPSVSSPEPAEKSRSSRRR 1745
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/258 (27%), Positives = 99/258 (38%), Gaps = 40/258 (15%)
Query: 1 MAASDTERDGLAPEKTSPDRDKK----KEQSEVSVSPRASKHHYSRSRSRSRERKRKSDN 56
M T G + + SPD +K QS S A SR RS S D
Sbjct: 1371 MKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDG 1430
Query: 57 EGR--KHRSRSRSKEGRRHESKDKS--SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH 112
R RSRS S G R S S S S D + +GR +SS
Sbjct: 1431 LPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPE----- 1485
Query: 113 KRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 172
+ ++ R RS S S S E ++ + +R++S S S +K+ +R+ ++SRS S +
Sbjct: 1486 PKALPQTPRPRSRSPS-SPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQE 1544
Query: 173 -----------------------KRRIRSRSRSRSRHRHRTRSRSR---TRSRSRDRKKR 206
K R R RSRS S+SR RSRS +
Sbjct: 1545 LDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV 1604
Query: 207 IEKPRRFSRSLSRTPSPP 224
+KPR R+ S + S P
Sbjct: 1605 KDKPRAAPRAQSGSDSSP 1622
Score = 45.8 bits (107), Expect = 8e-05
Identities = 46/170 (27%), Positives = 65/170 (38%), Gaps = 7/170 (4%)
Query: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
A + R+G PE T R ++ S S S +S S S S S S +
Sbjct: 2585 APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
Query: 62 RSRSRS--KEGRRHESKDKSSKKHKSEEHNDKEHSS--DKGRERLNSSENGEDRHKRKER 117
S S S K G + K S KK E + D R+ + S + +R + +
Sbjct: 2645 SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ 2704
Query: 118 KSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS 167
S R + +S S ER R R +S S R R+ R + SRS
Sbjct: 2705 PSPRDQ---QSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
Score = 41.2 bits (95), Expect = 0.002
Identities = 50/224 (22%), Positives = 71/224 (31%), Gaps = 24/224 (10%)
Query: 22 KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK----------------HRSRS 65
+++ S S S +S S S S S SD+EG +
Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588
Query: 66 RSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 125
+EGR E K+ S + SS +SS + SS S
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 126 SRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR---ERKRRI-----R 177
+ + KK R + R + SRS S ER+R R
Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708
Query: 178 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 221
+ S S R R +RS S R++ PR SR+P
Sbjct: 2709 DQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 36.2 bits (82), Expect = 0.060
Identities = 49/220 (22%), Positives = 88/220 (40%), Gaps = 10/220 (4%)
Query: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR-KERKSS 120
R RSRS +K + ++ +S + + + S +G + K S
Sbjct: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553
Query: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
+ RS S S S + + ++R+ R++SRS S S+SR R+ S E K + R+
Sbjct: 1554 QERSESDS-SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAP 1612
Query: 181 RSRSRHRHRTRSRSRT------RSRSRDRKK-RIEKPRRFSRSLSRTPSPPPFR-GRNTA 232
R++S ++ RSRS K R P S + S PP R R +
Sbjct: 1613 RAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS 1672
Query: 233 MDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAAT 272
+ E + ++ + E+ K + + +A++
Sbjct: 1673 RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS 1712
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 110 bits (275), Expect = 2e-24
Identities = 88/268 (32%), Positives = 132/268 (49%), Gaps = 12/268 (4%)
Query: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
AS R + SP R + Q R+ + SR+RSR RK GR +
Sbjct: 272 ASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQ 331
Query: 63 SRSRSKEGRRHESKD-KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
SRS SK +++S+ + + H + KE S R +SS+ + R RK S
Sbjct: 332 SRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSR---SSSKERDHRGSSSPRKES- 387
Query: 122 GRSHSRSRSRERRH-RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR---RIR 177
GRS S S +++R H RSRS + + RSRSR K+R RSR R +++R R R + R
Sbjct: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
Query: 178 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRG-RNTAMDAQ 236
RSRSRS ++ R SRSR+ +++RDR R P + R S+ SP R R + ++
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDR-SRSRSPSK-ERDHSQLGSPSKERDHRRSRSPSK 505
Query: 237 EALARRLERAKKLQEQREKEMVEKQKQQ 264
E R+ + K ++ R K++Q+
Sbjct: 506 ERQCRQSRSSSKERDHRRSRSPSKERQR 533
Score = 107 bits (268), Expect = 2e-23
Identities = 87/264 (32%), Positives = 130/264 (49%), Gaps = 17/264 (6%)
Query: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
+S ERD +SP ++ + QS SP + H SRSRS ++ R R K R
Sbjct: 370 SSSKERDHRG--SSSPRKESGRSQSG---SPNKQRDH-SRSRSPNKARDRSRSRSPYKAR 423
Query: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
RSRS+ + +S +K+ + + + S +K R+ S + R + + R S+
Sbjct: 424 DRSRSRSPNKARDCSRSRSPYKARDRS-RSRSPNKARDHSRSRSPNKARDRSRSRSPSKE 482
Query: 123 RSHSR--SRSRERRHR-----SRSRERKKSRSRSRER--KKSRSRSRERKKSRSRSRERK 173
R HS+ S S+ER HR S+ R+ ++SRS S+ER ++SRS S+ER++ +SRS ++
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 174 R-RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTA 232
R R +SRS S R ++RS S+ R R R R E+ RR SRS S R N
Sbjct: 543 RDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQ 602
Query: 233 MDAQEALARRLERAKKLQEQREKE 256
A E+A KE
Sbjct: 603 SGYSRPRASSKEKAHSRSRTPSKE 626
Score = 103 bits (258), Expect = 2e-22
Identities = 80/259 (30%), Positives = 125/259 (48%), Gaps = 17/259 (6%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKR-KSDNEGRKHRSRSRSKEGRRHES 75
S K K Q++ R H++SR+ S+ R +S ++ R HR S R+
Sbjct: 332 SRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRG---SSSPRKESG 388
Query: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-R 134
+ +S +K +H+ + S +K R+R S + R + + R ++ R SRSRS + R
Sbjct: 389 RSQSGSPNKQRDHS-RSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
Query: 135 HRSRSRERKKSR--SRSRERKKSRSRSRERKKSRSR--------SRERKRRIRSRSRSRS 184
RSRSR K+R SRSR K+R RSR R S+ R S+ER R RSRS S+
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR-RSRSPSKE 506
Query: 185 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLE 244
R ++RS S+ R R R E+ RR SRS ++ R + + +++ + E
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKE 566
Query: 245 RAKKLQEQREKEMVEKQKQ 263
R ++ KE +Q +
Sbjct: 567 RDRRRWRSPSKERERRQSR 585
Score = 94.0 bits (232), Expect = 2e-19
Identities = 73/228 (32%), Positives = 109/228 (47%), Gaps = 14/228 (6%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
S R KE+ + + + + RSRS S+ER + R+ RS S+ ++ RR S
Sbjct: 474 SRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER------QCRQSRSSSKERDHRRSRSP 527
Query: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 136
K ++ +S N KE + R E+ + R KER R RS S+ R R R+ R
Sbjct: 528 SKERQRRQSRSPN-KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERER-RQSR 585
Query: 137 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER---KRRIRSRSRSRSRHRHRTRS- 192
S S ER SRSRS ++ SR R K ++ SR R K S+SR+ S+ ++S
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
Query: 193 --RSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEA 238
RS RS R + + R S++ S +PS P G+ + D +A
Sbjct: 646 VPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQA 693
Score = 77.0 bits (188), Expect = 3e-14
Identities = 69/258 (26%), Positives = 109/258 (42%), Gaps = 45/258 (17%)
Query: 18 PDRDKKKEQSEVSVSPRASKHHYSRSR----SRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
P R+K +E+S ++ +RSR S+SR +R ++ SR RS +R+
Sbjct: 251 PSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRN 310
Query: 74 ESKDKSSKK-----HKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 128
S+ +S + + HS K + + + G + + R SHSRS
Sbjct: 311 HSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRS 370
Query: 129 RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 188
S+ER HR S RK+S R +S S +++R SRSRS +
Sbjct: 371 SSKERDHRGSSSPRKESG-----RSQSGSPNKQRDHSRSRSPNK---------------- 409
Query: 189 RTRSRSRTRSRS------RDRKKRIEKPRRFSRSLS------RTPSPPPFRGRNTAMDAQ 236
+R R+RSRS R R + K R SRS S R+ S P + R+ +
Sbjct: 410 ---ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRS 466
Query: 237 EALARRLERAKKLQEQRE 254
AR R++ ++R+
Sbjct: 467 PNKARDRSRSRSPSKERD 484
Score = 75.9 bits (185), Expect = 7e-14
Identities = 77/287 (26%), Positives = 123/287 (42%), Gaps = 41/287 (14%)
Query: 8 RDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERK-----------RKSDN 56
R G+A +P +K + + PR S S S+ R+ +K R S+
Sbjct: 151 RPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSEL 210
Query: 57 EGRKHRSRSRSKEGRRHESKD-----KSSKKHKSE-----EHNDKEHSSDKGRERLNSSE 106
++ ++ G + K SS+K KS +K +S + R+ S
Sbjct: 211 AVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYN 270
Query: 107 NGEDRHKRKERKSSRGRSHSRSRSRERRH---RSRSRERKKSRSRSRERK--------KS 155
R + + SR SRS S++R H RS S +R SR+RSR RK S
Sbjct: 271 QASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHS 330
Query: 156 RSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 215
+SRS + KS+++SR RR RS + SR+ + R+ S SR+ S+ RD + + R
Sbjct: 331 QSRSHSKGKSQNQSR-TPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGR 389
Query: 216 SLSRTP--------SPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 254
S S +P S P + R+ + AR R++ + R+
Sbjct: 390 SQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436
Score = 47.0 bits (110), Expect = 3e-05
Identities = 44/200 (22%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 22 KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSK 81
K+ + +S++P S + + + + KS R ++ R SSK
Sbjct: 5 KRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRS-LVPTKPATSRNSVMSPSSSK 63
Query: 82 KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE 141
KS + R R+ S R R S ++ + R SR R
Sbjct: 64 STKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRT 123
Query: 142 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201
+ SRS +R SR+ + R R+ + + SR R+ + + +R +S R R+
Sbjct: 124 PGRRGSRSSKRSPSRAST----PGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTS 179
Query: 202 DRKKRIEKPRRFSRSLSRTP 221
+R++ +PR S+ R P
Sbjct: 180 NRERSDSQPRNLSKKSYRPP 199
Score = 43.1 bits (100), Expect = 5e-04
Identities = 41/150 (27%), Positives = 59/150 (39%), Gaps = 15/150 (10%)
Query: 102 LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161
L S+++ K + R+ S S + +S S +R S +R +SR RS+
Sbjct: 32 LKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPS---NRPSSRSRVRSKA 88
Query: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 221
R SR + R + S R R T SR RT R R SRS R+P
Sbjct: 89 RTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGR------------RGSRSSKRSP 136
Query: 222 SPPPFRGRNTAMDAQEALARRLERAKKLQE 251
S GR A+ +A R+ Q+
Sbjct: 137 SRASTPGRIRTHGARPGMASRVRTPTSQQK 166
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 110 bits (274), Expect = 3e-24
Identities = 67/195 (34%), Positives = 112/195 (57%), Gaps = 11/195 (5%)
Query: 23 KKEQSEVSVSPRASKHHYSR--SRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSS 80
++ QS +S + K R SRSRSR R+R++ + R RSRSRS+ RR SK +S
Sbjct: 227 REAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSR--RRSHSKSRSR 284
Query: 81 KKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSR 140
++ KS + HS ++GR ++S+ + + + KE+K R ++ +S S RR RS SR
Sbjct: 285 RRSKSPRRR-RSHSRERGRRSRSTSKTRDKKKEDKEKK--RSKTPPKSYSTARRSRSASR 341
Query: 141 ERKKSRSRSRERKKSRSRSRERKKSRS----RSRERKRRIRSRSRSRSRHRHRTRSRSRT 196
ER++ RSRS R + RS +RK SRS R ++ K++ + + RSR T + ++
Sbjct: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKS 401
Query: 197 RSRSRDRKKRIEKPR 211
+ + +DR+++ E +
Sbjct: 402 KDKEKDRERKSESDK 416
Score = 86.3 bits (212), Expect = 5e-17
Identities = 71/245 (28%), Positives = 118/245 (48%), Gaps = 19/245 (7%)
Query: 31 VSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHND 90
VSP S+ + +R R++ + + +E RRH S++ ++ +
Sbjct: 206 VSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR 265
Query: 91 KEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKS---RS 147
S + R R +S + R +R+ + R RSHSR R R R S++R++KK +
Sbjct: 266 HRRSRSRSRRRSHS----KSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKK 321
Query: 148 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRI 207
RS+ KS S +R +SRS SRER+RR RSRS +RS + R+ R +RS S R K+
Sbjct: 322 RSKTPPKSYSTAR---RSRSASRERRRR-RSRSGTRSPKKPRSPKRKLSRSPSPRRHKK- 376
Query: 208 EKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQ-------EQREKEMVEK 260
EK + + SR + + D ++ R+ E K ++ E+ + EK
Sbjct: 377 EKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEK 436
Query: 261 QKQQE 265
+K++E
Sbjct: 437 EKKEE 441
Score = 66.6 bits (161), Expect = 4e-11
Identities = 47/150 (31%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 4 SDTERDGLAPEKTSPDRDKKKEQSEV--SVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
S + G TS RDKKKE E S +P S RSRS SRER+R+ G
Sbjct: 295 SHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGT-- 352
Query: 62 RSRSRSKEGRRHESKDKSSKKHKSE--EHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 119
RS + + +R S+ S ++HK E + DKE S D+ + + +D+ K +ERKS
Sbjct: 353 RSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKS 412
Query: 120 SRG---RSHSRSRSRERRHRSRSRERKKSR 146
+ +R E + +E+K+ +
Sbjct: 413 ESDKDVKQVTRDYDEEEQGYDSEKEKKEEK 442
Score = 59.3 bits (142), Expect = 7e-09
Identities = 56/201 (27%), Positives = 85/201 (42%), Gaps = 43/201 (21%)
Query: 101 RLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR 160
+LN G K SS+ + R RE + + + R +SRSRSR
Sbjct: 197 KLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSR 256
Query: 161 ERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS---------------RSRTRSRSRDRKK 205
R+++ S SR R+ R RSR RS S+ R R RS RSR+ S++RD+KK
Sbjct: 257 -RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKK 315
Query: 206 R------------------------IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALAR 241
E+ RR SRS +R+P P R ++ R
Sbjct: 316 EDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKL---SRSPSPR 372
Query: 242 RLERAKKLQEQREKEMVEKQK 262
R ++ KK + +E+ E+++
Sbjct: 373 RHKKEKKKDKDKERSRDERER 393
Score = 42.7 bits (99), Expect = 6e-04
Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Query: 15 KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK-HRSRSRSKEGRRH 73
K +DK KE+S SK S+ + + RERK +SD + ++ R ++G
Sbjct: 375 KKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDS 434
Query: 74 ESKDKSSKKH-KSEEHNDKEHSSDKGR-ERLNSSE-NGEDRHK 113
E + K KK ++ KE S +KG + L S+ NG+D H+
Sbjct: 435 EKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHE 477
Score = 36.2 bits (82), Expect = 0.060
Identities = 27/132 (20%), Positives = 51/132 (38%), Gaps = 7/132 (5%)
Query: 17 SPDRDKKKEQS---EVSVSPRASKHHYSRSRS----RSRERKRKSDNEGRKHRSRSRSKE 69
S R KK +S ++S SP +H + + RSR+ + +S ++ +K + + + +E
Sbjct: 350 SGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRE 409
Query: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129
+ KD +E S + +E E G + K + G S S+
Sbjct: 410 RKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
Query: 130 SRERRHRSRSRE 141
H +
Sbjct: 470 VNGDDHHEEDMD 481
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 107 bits (268), Expect = 2e-23
Identities = 65/192 (33%), Positives = 96/192 (50%), Gaps = 8/192 (4%)
Query: 15 KTSPDRDKKKE---QSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
+T +RD+ KE + S R +R R R RER++++D EG + R R R ++ R
Sbjct: 26 ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRD-R 84
Query: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131
+ E++ + K+ +++ H + + K +ER E DR + K+++ R R R R
Sbjct: 85 QRETERERDKERETDRHTETDRERQKQKER--EMERVRDREREKQKEMGRERQTDRETDR 142
Query: 132 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTR 191
ER R RER+ R R E + R R RERK+ R R RE K R R R R R R
Sbjct: 143 ERE-RQAERERETGRERKTE-DRHRERERERKRERERKRETKERERHTDMERERQRETDR 200
Query: 192 SRSRTRSRSRDR 203
R R R R+R
Sbjct: 201 KRDRQRESERER 212
Score = 97.1 bits (240), Expect = 3e-20
Identities = 62/190 (32%), Positives = 85/190 (44%), Gaps = 23/190 (12%)
Query: 4 SDTERDGLAPEKTSP-----DRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEG 58
+D ERD KT DR + +E++ R + R R RER+R D +
Sbjct: 27 TDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQR 86
Query: 59 RKHRSRSRSKEGRRHESKDKSSKKHKSEE-----HNDKEHSSDKGRERLNSSENGEDRHK 113
R R + +E RH D+ +K K E ++E + GRER E +R
Sbjct: 87 ETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRER-- 144
Query: 114 RKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERK---------KSRSRSRERKK 164
ER++ R R R R E RHR R RERK+ R R RE K + R R +RK+
Sbjct: 145 --ERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKR 202
Query: 165 SRSRSRERKR 174
R R ER+R
Sbjct: 203 DRQRESERER 212
Score = 96.7 bits (239), Expect = 4e-20
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 11/184 (5%)
Query: 32 SPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHN-- 89
S +H ++ + + R+R+R+ + + + R++ SK RH +D+ + ++ E +
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAK-ESKTEDRHSERDRQRDRERNRERDRD 61
Query: 90 -DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSR 148
++E +D+ ER E DR + ER+ + R R + R R + +ER+ R R
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETD-RERQKQKEREMERVR 120
Query: 149 SRERKKSRSRSRERKKSRSRSRERKR---RIRSRSRSR---SRHRHRTRSRSRTRSRSRD 202
RER+K + RER+ R RER+R R R R R RHR R R R R R R R+
Sbjct: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
Query: 203 RKKR 206
K+R
Sbjct: 181 TKER 184
Score = 96.3 bits (238), Expect = 5e-20
Identities = 69/227 (30%), Positives = 107/227 (47%), Gaps = 36/227 (15%)
Query: 38 HHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR---RHESKDKSSKKHKSEEHN---DK 91
H + + R RER+R++D E R R+KE + RH +D+ + ++ E + ++
Sbjct: 11 HTETETMDRQRERRRETDRE------RDRAKESKTEDRHSERDRQRDRERNRERDRDRER 64
Query: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 151
E +D+ ER E DR + ER+ + R R +R R + +ER+ R R RE
Sbjct: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE-RQKQKEREMERVRDRE 123
Query: 152 RKKSRSRSRERKKSRSRSRERKRRI-RSRSRSRSRHRH-RTRSRSRTRSRSRDRKKRIEK 209
R+K + RER+ R RER+R+ R R R R R R R R R R R+RK+ ++
Sbjct: 124 REKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE 183
Query: 210 PRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 256
R R+T M+ + R+ E +K QRE E
Sbjct: 184 -----------------RERHTDMERE----RQRETDRKRDRQRESE 209
Score = 94.0 bits (232), Expect = 2e-19
Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 4/195 (2%)
Query: 21 DKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR-KHRSRSRSKEGRRHESKDKS 79
+ K E R R RER R +++ +H R R ++ R+ +D+
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 80 SKKHK-SEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSR 138
++ K ++ +++ ++ R+R +E D+ + +R + R + + RE R R
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKERE-MERVR 120
Query: 139 SRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR- 197
RER+K + RER+ R RER++ R RE R ++ R R R R R R R R R
Sbjct: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
Query: 198 SRSRDRKKRIEKPRR 212
++ R+R +E+ R+
Sbjct: 181 TKERERHTDMERERQ 195
Score = 81.3 bits (199), Expect = 2e-15
Identities = 51/168 (30%), Positives = 75/168 (44%), Gaps = 10/168 (5%)
Query: 102 LNSSENGEDRHKRKE---RKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSR 158
+ S G H E R+ R R R R R + ++ R ++ R R RER + R R
Sbjct: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60
Query: 159 SRERKKSRSRSRERKR-RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSL 217
RER+K R ER+R R R R R R R R + R R DR+++ +K R R
Sbjct: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120
Query: 218 SRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
R GR D R +R ++ Q +RE+E ++K ++
Sbjct: 121 DREREKQKEMGRERQTD------RETDRERERQAERERETGRERKTED 162
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 107 bits (268), Expect = 2e-23
Identities = 73/206 (35%), Positives = 101/206 (49%), Gaps = 16/206 (7%)
Query: 51 KRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGED 110
K K+ E K + R R++E R D+ KK K E +E ++ RER +
Sbjct: 222 KIKATVEELKEKLRKRTEEPDR----DERLKKEKQER---EEREKERERER--------E 266
Query: 111 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
+RK R+ R R+R RERR RSRSR R SR+ R +SR R R + R RSR
Sbjct: 267 ERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR 326
Query: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
R RR RSRS RS +HR+RSR R RS+SRDRK + + R R RG +
Sbjct: 327 SRDRR-RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
Query: 231 TAMDAQEALARRLERAKKLQEQREKE 256
+ ++ +R + E +E +
Sbjct: 386 DKKSSVKSGSREKQSEDTNTESKESD 411
Score = 107 bits (268), Expect = 2e-23
Identities = 66/175 (37%), Positives = 102/175 (58%), Gaps = 11/175 (6%)
Query: 44 RSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLN 103
R R+ E R + K R KE R E +++ K+ + EE +KE + D+ R + +
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKE-REREREERERKRRREEEEREKERARDRERRKRS 293
Query: 104 SSENGEDRHKRK--ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161
S + RH + +R+ SR R H RSRSRERR RSRSR+R++SRS R +K RSRSR+
Sbjct: 294 RSRS---RHSSRTSDRRCSRSRDHKRSRSRERR-RSRSRDRRRSRSHDRSERKHRSRSRD 349
Query: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS 216
R++S+SR R + + RS+SR R + R +S+ + + S D+K ++ R +S
Sbjct: 350 RRRSKSRDR---KSYKHRSKSRDREQDR-KSKEKEKRGSDDKKSSVKSGSREKQS 400
Score = 100 bits (248), Expect = 3e-21
Identities = 56/199 (28%), Positives = 99/199 (49%), Gaps = 2/199 (1%)
Query: 10 GLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKE 69
G A K + + K+K + R + + RE++R+ + E R+ + R +E
Sbjct: 219 GYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEE 278
Query: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129
+ ++D+ +K +SD+ R + R +R+ R R RS S R
Sbjct: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 130 SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR-SRSRERKRRIRSRSRSRSRHRH 188
S ER+HRSRSR+R++S+SR R+ K RS+SR+R++ R S+ +E++ +S +S R
Sbjct: 339 S-ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSRE 397
Query: 189 RTRSRSRTRSRSRDRKKRI 207
+ + T S+ D K +
Sbjct: 398 KQSEDTNTESKESDTKNEV 416
Score = 86.3 bits (212), Expect = 5e-17
Identities = 58/159 (36%), Positives = 86/159 (54%), Gaps = 12/159 (7%)
Query: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
E KR E R + RE R + R RER++ RERK+ R ER+K R+R
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-----RERKRRREEE-EREKERAR 285
Query: 169 SRERKRRIRSRSR--SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 226
RER++R RSRSR SR+ R +RSR RSRSR+R++ + RR SRS R+
Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER---- 341
Query: 227 RGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
+ R+ + D + + +R + K + R++E K K++E
Sbjct: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380
Score = 80.9 bits (198), Expect = 2e-15
Identities = 56/193 (29%), Positives = 89/193 (46%), Gaps = 22/193 (11%)
Query: 8 RDGLAPEKTSPDRD---KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
++ L PDRD KK++Q + R R R RE + + R R
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
RS+ RH S+ + +S ++H + RER S R +R+ R R
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRS-----RDHKRSRSRERRRS----RSRDRRRSRSHDRSER 341
Query: 125 HSRSRSRERRHRSRSRERK----KSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
RSRSR+RR RS+SR+RK +S+SR RE+ + + ++K + S ++K ++S S
Sbjct: 342 KHRSRSRDRR-RSKSRDRKSYKHRSKSRDREQDR-----KSKEKEKRGSDDKKSSVKSGS 395
Query: 181 RSRSRHRHRTRSR 193
R + T S+
Sbjct: 396 REKQSEDTNTESK 408
Score = 73.6 bits (179), Expect = 3e-13
Identities = 43/167 (25%), Positives = 80/167 (47%), Gaps = 10/167 (5%)
Query: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
E+ +R +++E+ E + RSRSRSR R SD + R RS+ R
Sbjct: 264 EREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERR 323
Query: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
S+ + ++ +S + ++++H S + R+R R K ++RKS + RS SR R ++R
Sbjct: 324 RSRSRDRRRSRSHDRSERKHRS-RSRDR--------RRSKSRDRKSYKHRSKSRDREQDR 374
Query: 134 RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
+ + + + R +S + SR + E + S+ + K + S
Sbjct: 375 KSKEKEK-RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420
Score = 62.0 bits (149), Expect = 1e-09
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 7/145 (4%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRS--RSRERKRKSDNEGRKHRSR 64
E + E+ +K+ +S S R S SRSR RSR R+R+ + RSR
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
S + R+H S+ + ++ KS + +H S K R+R E ++++R S +S
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRS-KSRDR----EQDRKSKEKEKRGSDDKKS 389
Query: 125 HSRSRSRERRHRSRSRERKKSRSRS 149
+S SRE++ + E K+S +++
Sbjct: 390 SVKSGSREKQSEDTNTESKESDTKN 414
Score = 47.4 bits (111), Expect = 3e-05
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 17/117 (14%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSR--SRERKRKSDNEGRKHR 62
D +R + S RD+++ +S R+ + H SRSR R S+ R RKS KHR
Sbjct: 313 DHKRSRSRERRRSRSRDRRRSRSH----DRSERKHRSRSRDRRRSKSRDRKS----YKHR 364
Query: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 119
S+SR +E +D+ SK+ K + +D + SS K R SE+ K + K+
Sbjct: 365 SKSRDRE------QDRKSKE-KEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKN 414
Score = 37.7 bits (86), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEG-RRHES 75
S RD+++ +S R S H S+SR R ++RK K + +S K G R +S
Sbjct: 345 SRSRDRRRSKSR----DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
Query: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSEN 107
+D +++ +S+ N+ +S+ + ++ N
Sbjct: 401 EDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 107 bits (268), Expect = 2e-23
Identities = 73/206 (35%), Positives = 101/206 (49%), Gaps = 16/206 (7%)
Query: 51 KRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGED 110
K K+ E K + R R++E R D+ KK K E +E ++ RER +
Sbjct: 222 KIKATVEELKEKLRKRTEEPDR----DERLKKEKQER---EEREKERERER--------E 266
Query: 111 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
+RK R+ R R+R RERR RSRSR R SR+ R +SR R R + R RSR
Sbjct: 267 ERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR 326
Query: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
R RR RSRS RS +HR+RSR R RS+SRDRK + + R R RG +
Sbjct: 327 SRDRR-RSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
Query: 231 TAMDAQEALARRLERAKKLQEQREKE 256
+ ++ +R + E +E +
Sbjct: 386 DKKSSVKSGSREKQSEDTNTESKESD 411
Score = 107 bits (268), Expect = 2e-23
Identities = 66/175 (37%), Positives = 102/175 (58%), Gaps = 11/175 (6%)
Query: 44 RSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLN 103
R R+ E R + K R KE R E +++ K+ + EE +KE + D+ R + +
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKE-REREREERERKRRREEEEREKERARDRERRKRS 293
Query: 104 SSENGEDRHKRK--ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161
S + RH + +R+ SR R H RSRSRERR RSRSR+R++SRS R +K RSRSR+
Sbjct: 294 RSRS---RHSSRTSDRRCSRSRDHKRSRSRERR-RSRSRDRRRSRSHDRSERKHRSRSRD 349
Query: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS 216
R++S+SR R + + RS+SR R + R +S+ + + S D+K ++ R +S
Sbjct: 350 RRRSKSRDR---KSYKHRSKSRDREQDR-KSKEKEKRGSDDKKSSVKSGSREKQS 400
Score = 100 bits (248), Expect = 3e-21
Identities = 56/199 (28%), Positives = 99/199 (49%), Gaps = 2/199 (1%)
Query: 10 GLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKE 69
G A K + + K+K + R + + RE++R+ + E R+ + R +E
Sbjct: 219 GYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEE 278
Query: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129
+ ++D+ +K +SD+ R + R +R+ R R RS S R
Sbjct: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 130 SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR-SRSRERKRRIRSRSRSRSRHRH 188
S ER+HRSRSR+R++S+SR R+ K RS+SR+R++ R S+ +E++ +S +S R
Sbjct: 339 S-ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSRE 397
Query: 189 RTRSRSRTRSRSRDRKKRI 207
+ + T S+ D K +
Sbjct: 398 KQSEDTNTESKESDTKNEV 416
Score = 86.3 bits (212), Expect = 5e-17
Identities = 58/159 (36%), Positives = 86/159 (54%), Gaps = 12/159 (7%)
Query: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
E KR E R + RE R + R RER++ RERK+ R ER+K R+R
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREE-----RERKRRREEE-EREKERAR 285
Query: 169 SRERKRRIRSRSR--SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPF 226
RER++R RSRSR SR+ R +RSR RSRSR+R++ + RR SRS R+
Sbjct: 286 DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER---- 341
Query: 227 RGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
+ R+ + D + + +R + K + R++E K K++E
Sbjct: 342 KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380
Score = 80.9 bits (198), Expect = 2e-15
Identities = 56/193 (29%), Positives = 89/193 (46%), Gaps = 22/193 (11%)
Query: 8 RDGLAPEKTSPDRD---KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
++ L PDRD KK++Q + R R R RE + + R R
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
RS+ RH S+ + +S ++H + RER S R +R+ R R
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRS-----RDHKRSRSRERRRS----RSRDRRRSRSHDRSER 341
Query: 125 HSRSRSRERRHRSRSRERK----KSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
RSRSR+RR RS+SR+RK +S+SR RE+ + + ++K + S ++K ++S S
Sbjct: 342 KHRSRSRDRR-RSKSRDRKSYKHRSKSRDREQDR-----KSKEKEKRGSDDKKSSVKSGS 395
Query: 181 RSRSRHRHRTRSR 193
R + T S+
Sbjct: 396 REKQSEDTNTESK 408
Score = 73.6 bits (179), Expect = 3e-13
Identities = 43/167 (25%), Positives = 80/167 (47%), Gaps = 10/167 (5%)
Query: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
E+ +R +++E+ E + RSRSRSR R SD + R RS+ R
Sbjct: 264 EREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERR 323
Query: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
S+ + ++ +S + ++++H S + R+R R K ++RKS + RS SR R ++R
Sbjct: 324 RSRSRDRRRSRSHDRSERKHRS-RSRDR--------RRSKSRDRKSYKHRSKSRDREQDR 374
Query: 134 RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRS 180
+ + + + R +S + SR + E + S+ + K + S
Sbjct: 375 KSKEKEK-RGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420
Score = 62.0 bits (149), Expect = 1e-09
Identities = 41/145 (28%), Positives = 71/145 (48%), Gaps = 7/145 (4%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRS--RSRERKRKSDNEGRKHRSR 64
E + E+ +K+ +S S R S SRSR RSR R+R+ + RSR
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
S + R+H S+ + ++ KS + +H S K R+R E ++++R S +S
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRS-KSRDR----EQDRKSKEKEKRGSDDKKS 389
Query: 125 HSRSRSRERRHRSRSRERKKSRSRS 149
+S SRE++ + E K+S +++
Sbjct: 390 SVKSGSREKQSEDTNTESKESDTKN 414
Score = 47.4 bits (111), Expect = 3e-05
Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 17/117 (14%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSR--SRERKRKSDNEGRKHR 62
D +R + S RD+++ +S R+ + H SRSR R S+ R RKS KHR
Sbjct: 313 DHKRSRSRERRRSRSRDRRRSRSH----DRSERKHRSRSRDRRRSKSRDRKS----YKHR 364
Query: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 119
S+SR +E +D+ SK+ K + +D + SS K R SE+ K + K+
Sbjct: 365 SKSRDRE------QDRKSKE-KEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKN 414
Score = 37.7 bits (86), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEG-RRHES 75
S RD+++ +S R S H S+SR R ++RK K + +S K G R +S
Sbjct: 345 SRSRDRRRSKSR----DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQS 400
Query: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSEN 107
+D +++ +S+ N+ +S+ + ++ N
Sbjct: 401 EDTNTESKESDTKNEVNGTSEDIKSEGDTQSN 432
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 106 bits (264), Expect = 5e-23
Identities = 53/189 (28%), Positives = 96/189 (50%), Gaps = 2/189 (1%)
Query: 32 SPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDK 91
S R + R R RE++RK + ++ + R + + G+ E K K +K + E +
Sbjct: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
Query: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 151
K +++ + G K+K+ + R R + + R R+R+ R R ++R+K R R +E
Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR-RKKKRRKERKREKE 152
Query: 152 R-KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKP 210
R K+ R R + +K+ R + RER R+ R + R R R R + R + R + ++RKK +
Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212
Query: 211 RRFSRSLSR 219
R+ + R
Sbjct: 213 RQTDSQVFR 221
Score = 105 bits (262), Expect = 8e-23
Identities = 61/199 (30%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Query: 48 RERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSEN 107
RE +RK + R+ R R R KE +R K K KK K E + K RE+
Sbjct: 32 RESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 108 GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS 167
++R KRK+ K R R R R RER+ + +ER++ + RERK+ + R ++R+K R
Sbjct: 91 EKERRKRKKEKKKRERKQ-RGR-RERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 168 RSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFR 227
R +ER +R R R + + R + R R+R + R ++R+++ + R+ R R +
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNR-KERKKERERKERRERKKERKKERRKKKERKK 207
Query: 228 GRNTAMDAQEALARRLERA 246
R T + R L +
Sbjct: 208 DRKTDRQTDSQVFRPLRES 226
Score = 104 bits (259), Expect = 2e-22
Identities = 66/224 (29%), Positives = 109/224 (48%), Gaps = 11/224 (4%)
Query: 16 TSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHES 75
T + ++KKE+ E R + R R + ++KRK G++ + + +E +R E
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGE---DRHKRKERKSSRGRSHSRSRSRE 132
++K +K K E+ +E RER E E + +R+ERK + R R + R+
Sbjct: 90 REKERRKRKKEKKK-RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 133 RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192
R RERK+ + + ER+K R R+R K R + RERK R R R + R + R + +
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNR---KERKKERERKER-RERKKERKKERRKKKE 204
Query: 193 RSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGR--NTAMD 234
R + R R ++ +P R S + +R FR R +T +D
Sbjct: 205 RKKDRKTDRQTDSQVFRPLRES-AFNRVTVTGVFRYRIFHTGLD 247
Score = 95.5 bits (236), Expect = 8e-20
Identities = 55/189 (29%), Positives = 93/189 (49%), Gaps = 19/189 (10%)
Query: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
S+ +++ EK +R+K++++ + K R R + RERKRK + RK R
Sbjct: 34 SERKKERREREKRKREREKERKRER---GKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 64 ----RSRSKEGRRHESKDKSSKKHKSE-EHNDKEHSSDKGRERLNSSENGEDRHKRKERK 118
R R KE ++ E K + ++ K + E ++E + + RER + R K ++R+
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 119 SSRGR-----------SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS 167
RG+ + R R R+ R + RERK+ R R +ERKK R + +ERKK R
Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210
Query: 168 RSRERKRRI 176
R+ ++
Sbjct: 211 TDRQTDSQV 219
Score = 86.7 bits (213), Expect = 4e-17
Identities = 43/178 (24%), Positives = 89/178 (50%), Gaps = 3/178 (1%)
Query: 86 EEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKS 145
E KE + R+R E +R K++++K + R + RER+ + R ++RK+
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKK---RERGKERERKRKEREKQRKER 89
Query: 146 RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205
R + R ++K + RERK+ R R++K+ + R R + R R R + R + R ++RK+
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 206 RIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 263
E+ +R + R + + ++ R+ R +K + ++E+ +++K+
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
Score = 83.6 bits (205), Expect = 3e-16
Identities = 49/164 (29%), Positives = 84/164 (51%), Gaps = 4/164 (2%)
Query: 105 SENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSR-ERKKSRS--RSRE 161
SE ++R +R++RK R + R R ++ + + + RER K R R R ER+K R R +E
Sbjct: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
Query: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 221
R+K + ++R+R+ R R + + + R R + R R RKKR +K RR R +
Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
Query: 222 SPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
R R + R R ++ +E+ KE E++K+++
Sbjct: 154 GKRE-RKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196
Score = 75.1 bits (183), Expect = 1e-13
Identities = 43/161 (26%), Positives = 80/161 (49%), Gaps = 10/161 (6%)
Query: 105 SENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKK 164
++ +R K + + R R + R RER + + + +K+ R + RERK+ +ER+K
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-----KEREK 84
Query: 165 SRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 224
R RE++RR R + + + + R R R R + + R ++R K RR + R
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGR-RERKKKKERKERERENKQRRERKRKKRRKK-- 141
Query: 225 PFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
+ R +E R +R K+ +E+REK+ +K+++
Sbjct: 142 --KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180
Score = 62.0 bits (149), Expect = 1e-09
Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 2/128 (1%)
Query: 137 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRT 196
S S K R ERKK R +RK+ R + R+R+R + + + + R R + R R R
Sbjct: 21 SCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR- 79
Query: 197 RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 256
+ R + RK+R EK RR R + RGR +E R E ++ + +R+K
Sbjct: 80 KEREKQRKERREKERR-KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
Query: 257 MVEKQKQQ 264
+K++++
Sbjct: 139 RKKKRRKE 146
Score = 61.6 bits (148), Expect = 1e-09
Identities = 36/145 (24%), Positives = 72/145 (49%), Gaps = 16/145 (11%)
Query: 128 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRER-------KKSRSRSRERKRRIRSRS 180
S+ +R R +ER++ R RER+K R RER +K R R +ER+R+ + R
Sbjct: 26 SKPCTQRESERKKERREREKRKREREKE--RKRERGKKEKKKRKKRERGKERERKRKERE 83
Query: 181 RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALA 240
+ R R + R + + + R+RK+R + R+ + R R +
Sbjct: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE-------RERENKQRRERKRK 136
Query: 241 RRLERAKKLQEQREKEMVEKQKQQE 265
+R ++ ++ + +REKE +++++++
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRK 161
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 104 bits (260), Expect = 1e-22
Identities = 73/252 (28%), Positives = 117/252 (46%), Gaps = 47/252 (18%)
Query: 15 KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHE 74
K + D+++E+ V + R R R RER+RK K +R+R +E +
Sbjct: 70 KDADGDDRQRERDRVREKTEKER---DRDRKRDRERRRK-----EKETNRNRDREKQTEI 121
Query: 75 SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERR 134
+D+ +K K +E D+GRER E DR K +ER++ + R R E R
Sbjct: 122 ERDREREKQKG-----RERERDRGRER----ERDRDREKERERQTEKDRDGQRETETE-R 171
Query: 135 HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS-RSRSRSRHRHRTRSR 193
R R RE++K R R+R + R +ER++ R R+R+R+ ++ R R R R R
Sbjct: 172 ERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDR 231
Query: 194 SRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQR 253
R R R RDR K ++ R R+ ER K+ +++R
Sbjct: 232 RRERQRDRDRGKERDRER----------------------------DRKEERKKERKKER 263
Query: 254 EKEMVEKQKQQE 265
+KE EK+K+++
Sbjct: 264 KKERKEKKKEEK 275
Score = 104 bits (260), Expect = 1e-22
Identities = 64/217 (29%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
ERD + EKT +RD+ +++ R + +R+R R ++ + + D E K + R R
Sbjct: 80 ERDRVR-EKTEKERDRDRKRDR---ERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
Query: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 126
++ R +D+ +K E E D RE E +R K+KER++ R R
Sbjct: 136 ERDRGRERERDRDREK---ERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQ 192
Query: 127 RSRSRERRH---RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER-KRRIRSRSRS 182
R +ER R R R+RK R RE + R +R++ R R R+R K R R R R
Sbjct: 193 RDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
Query: 183 RSRHRHRTRSRSRTR-SRSRDRKKRIEKPRRFSRSLS 218
R + R + R + R + ++ K+R +K R++ +S
Sbjct: 253 EERKKERKKERKKERKEKKKEEKRREDKKRKWGEGIS 289
Score = 92.0 bits (227), Expect = 9e-19
Identities = 51/182 (28%), Positives = 88/182 (48%), Gaps = 8/182 (4%)
Query: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
++ RD + DR+++K++ R + R R + RER+ + D +G++
Sbjct: 109 TNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETE 168
Query: 64 RSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
R ++ R + K++ ++E D++ ++K RER E R + ER+ R
Sbjct: 169 TERERDREREKQKER-----ETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
Query: 124 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183
R R RR R R R+R K R R R+RK+ R +ERKK R + R+ K++ R +
Sbjct: 224 EGERETDR-RRERQRDRDRGKERDRERDRKE--ERKKERKKERKKERKEKKKEEKRREDK 280
Query: 184 SR 185
R
Sbjct: 281 KR 282
Score = 76.6 bits (187), Expect = 4e-14
Identities = 53/173 (30%), Positives = 77/173 (44%), Gaps = 12/173 (6%)
Query: 96 DKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKK- 154
D R RL S E+ + K + G R R R R + R+R + R R R RK+
Sbjct: 48 DFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEK 107
Query: 155 --SRSRSRERKKSRSRSRER---KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDR------ 203
+R+R RE++ R RER K R R R R R R R R R + R R +DR
Sbjct: 108 ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET 167
Query: 204 KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKE 256
+ E+ R + R R R+T + + R +R +K Q +R++E
Sbjct: 168 ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRE 220
Score = 54.7 bits (130), Expect = 2e-07
Identities = 33/120 (27%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
D ER+ +T DRD++++ + R + R R ER+R++D EG + R
Sbjct: 174 DREREKQKERETERDRDRQRDTEKER--ERQTDRERDRQRKTQTERQRETDREGERETDR 231
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
R ++ R K++ ++ + EE KE ++ +ER + E R + K+RK G S
Sbjct: 232 RRERQRDRDRGKERDRERDRKEERK-KERKKERKKER-KEKKKEEKRREDKKRKWGEGIS 289
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 104 bits (260), Expect = 1e-22
Identities = 101/348 (29%), Positives = 159/348 (45%), Gaps = 46/348 (13%)
Query: 1 MAASDTERDGLA--------PEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSR---E 49
+ ASD RD A PE+ S ++K+ E+ V + + ++++R + E
Sbjct: 1756 LLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKE 1815
Query: 50 RKRKSDNEGRKHRSRSRSKEGRRHESKDKS---SKKHKSEEHNDKEHSSDKGRERLNSSE 106
+KR S R RS+S + R+ S+ +S + KS+ H + S + R R SS
Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSS- 1874
Query: 107 NGEDRHKRKERKSSRGR----SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR-E 161
+ R SRGR R RS + R +SR R+RK+S SR RK R+RSR
Sbjct: 1875 --------RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD-NRKTVRARSRTP 1925
Query: 162 RKKSRSRSRERKRRIRSRSRSRS-----RHRHRTRS-RSRTRS-RSRDRKKRIEKPRRFS 214
++SRS + R+RR RS R RS R RT S RSRT S RSR +R P R S
Sbjct: 1926 SRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1985
Query: 215 RSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGG 274
R+ SR P R R+ ++ + + + R ++ + + +++ + ++ G
Sbjct: 1986 RTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGR 2045
Query: 275 SVLNVAALLASGTQVTPQIAMAAQMAALQAKAL-AETGIAVPSYYNPA 321
S + L A ++A A A+ A+ G+ +P PA
Sbjct: 2046 SPKRLTDL---------DKAQLLEIAKANAAAMCAKAGVPLPPNLKPA 2084
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 104 bits (260), Expect = 1e-22
Identities = 101/348 (29%), Positives = 159/348 (45%), Gaps = 46/348 (13%)
Query: 1 MAASDTERDGLA--------PEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSR---E 49
+ ASD RD A PE+ S ++K+ E+ V + + ++++R + E
Sbjct: 1756 LLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKE 1815
Query: 50 RKRKSDNEGRKHRSRSRSKEGRRHESKDKS---SKKHKSEEHNDKEHSSDKGRERLNSSE 106
+KR S R RS+S + R+ S+ +S + KS+ H + S + R R SS
Sbjct: 1816 KKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSS- 1874
Query: 107 NGEDRHKRKERKSSRGR----SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR-E 161
+ R SRGR R RS + R +SR R+RK+S SR RK R+RSR
Sbjct: 1875 --------RSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD-NRKTVRARSRTP 1925
Query: 162 RKKSRSRSRERKRRIRSRSRSRS-----RHRHRTRS-RSRTRS-RSRDRKKRIEKPRRFS 214
++SRS + R+RR RS R RS R RT S RSRT S RSR +R P R S
Sbjct: 1926 SRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1985
Query: 215 RSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGG 274
R+ SR P R R+ ++ + + + R ++ + + +++ + ++ G
Sbjct: 1986 RTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGR 2045
Query: 275 SVLNVAALLASGTQVTPQIAMAAQMAALQAKAL-AETGIAVPSYYNPA 321
S + L A ++A A A+ A+ G+ +P PA
Sbjct: 2046 SPKRLTDL---------DKAQLLEIAKANAAAMCAKAGVPLPPNLKPA 2084
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 104 bits (259), Expect = 2e-22
Identities = 63/223 (28%), Positives = 106/223 (47%), Gaps = 21/223 (9%)
Query: 42 RSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSD----- 96
+S R RER+ ++ EG+K R R KE R E + + +K + E KE +
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 97 ---KGRERLNSSENGEDRHKRKER-KSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152
K R R ++ GE++ KRK++ K RGR+ + RER+ + ERK+ + ER
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 153 KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRR 212
+K R R +K+ R + E++ + + R + R R R + R + R+RK+R E+ +
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR---KERKKERERKERRERKKE 211
Query: 213 FSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREK 255
+ R R N R ER K+ +++R+K
Sbjct: 212 RKKKEERKKERQKDRQTNW---------REKERGKRERKERKK 245
Score = 101 bits (252), Expect = 1e-21
Identities = 61/210 (29%), Positives = 102/210 (48%), Gaps = 13/210 (6%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
+T ++G K + ++KKE+ E K R + R RER +K RK R
Sbjct: 46 ETRKEG----KKERESERKKERRE------REKRKREREKERKRERGKKEKKGERKKEER 95
Query: 65 SRSKEGRRHESKDKSSK-KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
R K R E+K+ K K K +E ++ +S +G+ER E + K +ERK
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 124 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183
+ R++R R + E+++ R + +ERK+ + R R RK+ + ++RR R + R +
Sbjct: 156 KERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 184 SRHRHRTRSRSR-TRSRSRDRKKRIEKPRR 212
R + R + R T R ++R KR K R+
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 99.4 bits (246), Expect = 6e-21
Identities = 60/200 (30%), Positives = 102/200 (51%), Gaps = 12/200 (6%)
Query: 21 DKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSS 80
+ +KE + S R + R R RE++RK + G+K + R KE R K +
Sbjct: 46 ETRKEGKKERESERKKERREREKRKREREKERKRER-GKKEKKGERKKE-ERERKKRRRE 103
Query: 81 KKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSR 140
K++K E +K +K +ER +S+ G++R +++ERK R + R R++ R + R
Sbjct: 104 KENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERK----REERKERERKKEEREKER 158
Query: 141 ERKKSRSRSRER---KKSRSRSRERKKSRSRSRERKRRIRSRSRS--RSRHRHRTRSRSR 195
ERK+ + R R++ K+ + +ERK+ + R R RK R + R R R R + R + R
Sbjct: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
Query: 196 TRSRSRDRKKRIEKPRRFSR 215
+ R +DR+ + R R
Sbjct: 219 KKERQKDRQTNWREKERGKR 238
Score = 98.2 bits (243), Expect = 1e-20
Identities = 52/191 (27%), Positives = 93/191 (48%), Gaps = 3/191 (1%)
Query: 23 KKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHE-SKDKSSK 81
++ + E+ K S + RER+++ E K R R R K+ ++ E K++ +
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRK-REREKERKRERGKKEKKGERKKEERER 97
Query: 82 KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE 141
K + E +KE + R++ E G + KER+ R + RER+ R +E
Sbjct: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE 157
Query: 142 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201
R++ + RERK+ + ERK+ + R+++ R R + R + R R R R + R +
Sbjct: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRERNR-KERKKERERKERRERKKERKKKE 216
Query: 202 DRKKRIEKPRR 212
+RKK +K R+
Sbjct: 217 ERKKERQKDRQ 227
Score = 70.1 bits (170), Expect = 4e-12
Identities = 45/195 (23%), Positives = 92/195 (47%), Gaps = 4/195 (2%)
Query: 73 HESKDKSSKKHKSE-EHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131
H SK + +SE ++E + K ++ SE ++R +R++RK R + R R +
Sbjct: 24 HISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK 83
Query: 132 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIR-SRSRSRSRHRHRT 190
+ + R +E ++ + R RE++ +E++K + +ER R + + R R R R
Sbjct: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKK-EKKERGRTSKEGKERERKEERKRE 142
Query: 191 RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQ 250
+ R R + +R+K E+ R R + R + ++ R ER K+ +
Sbjct: 143 ERKERER-KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
Query: 251 EQREKEMVEKQKQQE 265
+ +E +++K++E
Sbjct: 202 RKERRERKKERKKKE 216
Score = 59.7 bits (143), Expect = 5e-09
Identities = 40/142 (28%), Positives = 73/142 (51%), Gaps = 5/142 (3%)
Query: 124 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183
SH + +S RER++ +E KK R ERKK R R RE+++R R + R R
Sbjct: 23 SHISKPCTQPGWQSEIREREREIETRKEGKKE--RESERKKER-REREKRKREREKERKR 79
Query: 184 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRL 243
R + + + R R +++R ++ + R RGR T+ + +E R+
Sbjct: 80 ERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGR-TSKEGKER-ERKE 137
Query: 244 ERAKKLQEQREKEMVEKQKQQE 265
ER ++ +++RE++ E++K++E
Sbjct: 138 ERKREERKERERKKEEREKERE 159
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 103 bits (258), Expect = 2e-22
Identities = 61/197 (30%), Positives = 99/197 (50%), Gaps = 11/197 (5%)
Query: 31 VSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHND 90
+ R + R R R++ER R+ D E K R R R ++ R +D+ K+ + + D
Sbjct: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDR-D 115
Query: 91 KEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE-RRHRSRSRERK-----K 144
+E +++ ER E DR + K+R+ R R + RE + R RER+ +
Sbjct: 116 RETETERQEER----ERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171
Query: 145 SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRK 204
R R RER+K R R+R + R R +E + R R R + R + R+R R R R + RDR+
Sbjct: 172 YRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRE 231
Query: 205 KRIEKPRRFSRSLSRTP 221
++ EK R +++ P
Sbjct: 232 RQREKDRDRQKAIDCVP 248
Score = 103 bits (257), Expect = 3e-22
Identities = 62/193 (32%), Positives = 102/193 (52%), Gaps = 9/193 (4%)
Query: 20 RDKKKEQSEVSVSPRASKHHYSRSRS--RSRERKRKSDNEGRKHRSRSRSKEGRRHESKD 77
R++++++ RA + H + R + R+R+RK D E ++ R R R +E R +D
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRE--RWGDRD 115
Query: 78 KSSKKHKSEE-HNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 136
+ ++ + EE ++ +K RER E G D K +E ++ + R R R+R
Sbjct: 116 RETETERQEERERQRDRKREKDRERQRQREIGID--KDREIETEKDRDREREMGETERYR 173
Query: 137 SRSRERKKSRSRSRERKKSRSRSRE-RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSR 195
R RER+K R R+R + R R +E R++ R R +ER++ R R R R R + R R R
Sbjct: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKD-RYRERETGRDRDKERDRER 232
Query: 196 TRSRSRDRKKRIE 208
R + RDR+K I+
Sbjct: 233 QREKDRDRQKAID 245
Score = 88.6 bits (218), Expect = 1e-17
Identities = 58/210 (27%), Positives = 91/210 (43%), Gaps = 7/210 (3%)
Query: 68 KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 127
+E R +++ K+ K E H +K+ +K R+R + R + ++RK R R
Sbjct: 58 RERERQRERERQRKRAK-ERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
Query: 128 SRSRER---RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 184
ER R R R R+R+K R R R+R+ + RE + + R RER+ R R R
Sbjct: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
Query: 185 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLE 244
R R + R R R R R R+K + R R + +R R T D + R +
Sbjct: 177 RERQKQRETRRDRDRERQREK---EDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
Query: 245 RAKKLQEQREKEMVEKQKQQEIAAAAATGG 274
R K Q+ + V + + + A G
Sbjct: 234 REKDRDRQKAIDCVPGRWEVTVMAVDCVPG 263
Score = 84.7 bits (208), Expect = 1e-16
Identities = 53/186 (28%), Positives = 93/186 (50%), Gaps = 16/186 (8%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRK--SDNEGRKHR 62
+ +R+ K + +R ++K++ R K R R R R+RKR+ D +
Sbjct: 61 ERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETET 120
Query: 63 SRSRSKEGRRHESKDKSSKKHKSEE---HNDKEHSSDKGRERLNSSENGE-------DRH 112
R +E +R ++K ++ + E D+E ++K R+R E GE +R
Sbjct: 121 ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDR--EREMGETERYRDRERE 178
Query: 113 KRKERKSSRGRSHSRSRSRERRHRSRSR--ERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
++K+R++ R R R R +E R R R R ER+K R R RE + R + R+R++ R + R
Sbjct: 179 RQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDR 238
Query: 171 ERKRRI 176
+R++ I
Sbjct: 239 DRQKAI 244
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 103 bits (256), Expect = 4e-22
Identities = 65/214 (30%), Positives = 105/214 (49%), Gaps = 16/214 (7%)
Query: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRAS--KHHYSRSRSRSRERKRKSDNEGR 59
+++ D + P+RD+ E+ + +S + H R R +RER ++ +
Sbjct: 587 SSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSP-- 644
Query: 60 KHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 119
R + R+ E R E +++ + +++ D+ RER DR + +ER+
Sbjct: 645 -IRHQGRNDELERDERREERRVDRVDDRRDERARERDRERER--------DRERERERER 695
Query: 120 SRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR--SRSRERKKSRSRSRERKRRIR 177
R R + R ER R+R RER++ + R RER + R R RER++ R R +ER+R
Sbjct: 696 ERDREREKERELERE-RAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754
Query: 178 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPR 211
R R R R R R R R R R R+R+R K E+ R
Sbjct: 755 ERERERERERERERERERERERARERDKERERQR 788
Score = 103 bits (256), Expect = 4e-22
Identities = 78/284 (27%), Positives = 125/284 (44%), Gaps = 53/284 (18%)
Query: 19 DRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDK 78
+RD+++E+ V R R+R R RER+R + E + R R R +E R +++
Sbjct: 655 ERDERREERRVD---RVDDRRDERARERDRERERDRERERERERERDREREKERELERER 711
Query: 79 SSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSR 138
+ ++ + E KE ++ R+R D + +ER+ R R R R RE R R R
Sbjct: 712 ARERERERE---KERDRERDRDR--------DHDRERERERERDREKEREREREERERER 760
Query: 139 SRERKKSRSRSRERKKSRSRSRERK---------KSRSRSRERKRRIRSRSRSRSRHRHR 189
RER++ R R RER+++R R +ER+ K R RE++ IR R H R
Sbjct: 761 ERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDER 820
Query: 190 TRSRSRTRSRSRDRKKRIEKPRR-----------------FSRSLSRTPSPPPFRG---- 228
+S+ R R+ ++ K RR R LS+ P R
Sbjct: 821 -KSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879
Query: 229 -----RNTAMDAQEALARRLERAKKLQEQREKE---MVEKQKQQ 264
R ++ R E +++ +EQ KE V+KQ++Q
Sbjct: 880 HLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQ 923
Score = 99.8 bits (247), Expect = 4e-21
Identities = 65/228 (28%), Positives = 109/228 (47%), Gaps = 8/228 (3%)
Query: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR-KHRSRSRSKEGRR 72
E+ +RD++ + E P + H R+ R+ +R+ R R R++E R
Sbjct: 623 ERRHGERDRR-DNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDR 681
Query: 73 HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 132
+D+ ++ + E D+E ++ ER + E +R K ++R+ R R H R R RE
Sbjct: 682 ERERDRERERERERER-DREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740
Query: 133 R---RHRSRSRER-KKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR-HR 187
R R + R RER ++ R R RER++ R R RER+++R R +ER+R+ + + R R
Sbjct: 741 RERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDR 800
Query: 188 HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDA 235
R R RD + +R+ S +P P R R + D+
Sbjct: 801 REKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDS 848
Score = 95.1 bits (235), Expect = 1e-19
Identities = 76/252 (30%), Positives = 119/252 (47%), Gaps = 23/252 (9%)
Query: 13 PEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRR 72
PEK S R + Q + S S ++ H +RS ER R + + R ++R S E RR
Sbjct: 571 PEKGS--RGSRGSQID-SHSSNSNYHDSWETRSSYPERDRYPERDNRD-QARDSSFE-RR 625
Query: 73 HESKDKSSKKHKSEE---------HNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
H +D+ + + + ND+ ++ ER + + +ER R R
Sbjct: 626 HGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERER 685
Query: 124 SHSRSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 182
R R RER R R R +ER+ R R+RER++ R + R+R++ R R +R+R R R R
Sbjct: 686 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERE-RERERD 744
Query: 183 RSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 242
R + R R R R R R R+R++ E+ R R+ R + R D ++ R
Sbjct: 745 REKERERER-EERERERERERERERERERERERARERD------KERERQRDWEDKDKGR 797
Query: 243 LERAKKLQEQRE 254
+R +K +E RE
Sbjct: 798 DDRREKREEIRE 809
Score = 94.4 bits (233), Expect = 2e-19
Identities = 76/276 (27%), Positives = 123/276 (44%), Gaps = 19/276 (6%)
Query: 5 DTER--DGLAPEKTSPDRDKKKEQSEVSVSPRASKHH---------YSRSRSRSRERKRK 53
DT R D E S R+ +E+S + S++ RSR R E K
Sbjct: 514 DTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK 573
Query: 54 SDNEGRKHRSRSRSKEGRRHESKDKSS---KKHKSEEHNDKEHSSDKGRERLNSSENGED 110
R + S S H+S + S ++ + E ++++ + D ER + + D
Sbjct: 574 GSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRD 633
Query: 111 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
+R +R SS R R+ ER R ER+ R R +++R R RER++ R R R
Sbjct: 634 NRERDQRPSSPIRHQGRNDELERDERRE--ERRVDRVDDRRDERARERDRERERDRERER 691
Query: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
ER+R R R R + R R R+R R R R ++R + ++ R R R + R
Sbjct: 692 ERERE-RDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERE 750
Query: 231 TAMDAQEALARRLERAKKLQEQREKEMV-EKQKQQE 265
+ +E R ER ++ + +RE+E E+ K++E
Sbjct: 751 REREERER-ERERERERERERERERERARERDKERE 785
Score = 89.4 bits (220), Expect = 6e-18
Identities = 65/255 (25%), Positives = 109/255 (42%), Gaps = 11/255 (4%)
Query: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH-----RSRSRSKEGRRHE 74
RD +++ R+ ++ R S E + +S NE R RSR + E
Sbjct: 513 RDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPE 572
Query: 75 SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH-KRKERKSSRGRSHSRSRSRER 133
+ S+ + + H+ + D R SS DR+ +R R +R S R
Sbjct: 573 KGSRGSRGSQIDSHSSNSNYHDSWETR--SSYPERDRYPERDNRDQARDSSFERRHGERD 630
Query: 134 RHRSRSRERKKS---RSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 190
R +R R+++ S R + R + R RE ++ R R R R R R R R R
Sbjct: 631 RRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERE 690
Query: 191 RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQ 250
R R R R R R++++ +E+ R R R R R+ D + R +R K+ +
Sbjct: 691 RERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERE 750
Query: 251 EQREKEMVEKQKQQE 265
+RE+ E+++++E
Sbjct: 751 REREERERERERERE 765
Score = 74.7 bits (182), Expect = 2e-13
Identities = 74/307 (24%), Positives = 126/307 (41%), Gaps = 47/307 (15%)
Query: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNE------ 57
S +R P SP R+K + E + +H R+R++ S E
Sbjct: 380 SSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQD 439
Query: 58 ---GRKHRSRSRSKEGR-RHESKDKSSKK--HKSEEHNDKEHSSDKGRERLNSSE----- 106
R HR ++GR R +++D ++ S + D D R+ S +
Sbjct: 440 QSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSR 499
Query: 107 -----------NGEDRHKRKERKSSRGRSHSRSRSRERRHRS--RSRERKKSRSRSRERK 153
G D H++++ RS+ R+ RE R+ R+ R +SRS R +
Sbjct: 500 STRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDR 559
Query: 154 KSRSRSRERKKSRSRSR-ERKRRIRSRS---------RSRSRHRHRTRSRSR-TRSRSRD 202
RSR R + SR R +I S S +RS + R R R R ++RD
Sbjct: 560 MGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARD 619
Query: 203 ---RKKRIEKPRRFSRSLSRTPSPP-PFRGRNTAMDAQEALARRLERAKKLQEQREKEMV 258
++ E+ RR +R + PS P +GRN ++ E R R ++ ++R++
Sbjct: 620 SSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDE--RREERRVDRVDDRRDERAR 677
Query: 259 EKQKQQE 265
E+ +++E
Sbjct: 678 ERDRERE 684
Score = 73.9 bits (180), Expect = 3e-13
Identities = 60/206 (29%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79
R + + S ++ + S SR RE+ + + G + + K G S+ S
Sbjct: 1207 RSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGE--PSRSTS 1264
Query: 80 SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR--- 136
S + S H+ + S + R+ + S + + R + +ER H R R RERR
Sbjct: 1265 SDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYE---HDRERERERRDTRQR 1321
Query: 137 --SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIR-SRSRSRSRHRHRTRSR 193
R ++ R+R R+R + R R RER K R RER+R I S R R R R RT
Sbjct: 1322 EWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFES 1381
Query: 194 SRTRSRSRDRKKRIEKPRRFSRSLSR 219
S+ S R K + R S SR
Sbjct: 1382 SQIESVKRCEAKLEGEHERDLESTSR 1407
Score = 72.4 bits (176), Expect = 8e-13
Identities = 65/213 (30%), Positives = 89/213 (41%), Gaps = 20/213 (9%)
Query: 13 PEKTSPDRDKKK----EQSEVSVSPRASKHHYS-RSRSRSRERKRKS--DNEGRKH---- 61
P T D +K ++S S R+++ H S R RS S + +S D GRK
Sbjct: 1171 PHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHS 1230
Query: 62 --RSRSRSKE----GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK 115
R R ++K G R D+ + S + S R +S E+ H R
Sbjct: 1231 GSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRS 1290
Query: 116 ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRR 175
SR R + R R R R RER+ +R R +R + R R + R R RER+R
Sbjct: 1291 GSFDSRDRL--QERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERE 1348
Query: 176 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIE 208
R + R R R R S S R R RDR + E
Sbjct: 1349 -RDKRRDLDRERERLISDSVERDRDRDRDRTFE 1380
Score = 69.3 bits (168), Expect = 6e-12
Identities = 73/295 (24%), Positives = 116/295 (39%), Gaps = 31/295 (10%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQS---EVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
D +RD + +RD++KE+ E R + R R R RER R+ D E +
Sbjct: 728 DRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQ 787
Query: 62 RSRSRSKEGR--RHESKD---------------KSSKKHKSEEHNDKEHSSDKGRERLNS 104
R +GR R E ++ KS K++++E S + RE
Sbjct: 788 RDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPD 847
Query: 105 SE--NGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE-RKKSRSRSRERKKSRSRSRE 161
S+ N D K R S+ SRS H + R+ R K R ERK+S R E
Sbjct: 848 SDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEE 907
Query: 162 RKKSRSRSRERKRRIRSRSRSRSRHR------HRTRSRSRTRSRSRDRKKRIEKPRRFSR 215
++ S K+R ++ SR R H T R+ D K+ K ++
Sbjct: 908 QELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPI 967
Query: 216 SLSRTPSPPPFRG--RNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAA 268
+ RG T+ D Q ++ ++ K ++++R+K + E AA
Sbjct: 968 KKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAA 1022
Score = 67.4 bits (163), Expect = 2e-11
Identities = 61/275 (22%), Positives = 114/275 (41%), Gaps = 22/275 (8%)
Query: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKS-DNEGRKH 61
A + ER+ DRD+ + R + R R + RER+R+ + E +
Sbjct: 712 AREREREREKERDRERDRDRDHD--------RERERERERDREKEREREREERERERERE 763
Query: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERL------NSSENGEDRHKRK 115
R R R +E R ++++ ++ + + DK+ D RE+ + +G D K K
Sbjct: 764 RERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSK 823
Query: 116 ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRR 175
+R + G R + RR S + S E+ + S+ ++SRS S
Sbjct: 824 KRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTE 883
Query: 176 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR---IEKPRRFSRSL-SRTPSPPPFRGRNT 231
R + R + R R S R ++ K++ ++K R + L S G +
Sbjct: 884 DR-QGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942
Query: 232 AMDAQEALARRLERAKKLQEQREKEMVEKQKQQEI 266
+ D + + E KK + Q K+ ++K+K+ ++
Sbjct: 943 SEDRETSDRAHDENKKKAKIQ--KKPIKKKKEDDV 975
Score = 65.5 bits (158), Expect = 9e-11
Identities = 69/248 (27%), Positives = 104/248 (41%), Gaps = 25/248 (10%)
Query: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79
R +K E V++ + + RS S R S+ R RS S + D+S
Sbjct: 1164 RVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNR-SNRSHTSGRLRSPSNDSAHRSGDDQS 1222
Query: 80 SKKHKSEEHNDKEHSSDKGRERLNSSE-NGE-----DRHKRKE--RKSSRGRSHSRSRSR 131
+K HS + RE+ S E GE D+ KR E R +S R SRS S
Sbjct: 1223 GRKRVL-------HSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHS- 1274
Query: 132 ERRHRSRSRERKKSRSRS---RERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 188
RR S + SRS S R+R + R R ++ R+ ++R R + R+
Sbjct: 1275 SRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRN 1334
Query: 189 RTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKK 248
R R R R R R R+R KR + R R +S + R R+ ++ + +E K+
Sbjct: 1335 RDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQ-----IESVKR 1389
Query: 249 LQEQREKE 256
+ + E E
Sbjct: 1390 CEAKLEGE 1397
Score = 60.1 bits (144), Expect = 4e-09
Identities = 73/270 (27%), Positives = 109/270 (40%), Gaps = 62/270 (22%)
Query: 14 EKTSPDRDKKKEQSEVSV--SPRASKHHYSRSRSRSRERK-------------------- 51
E+ RDK + S SP +S+HH S S+S S ++
Sbjct: 305 ERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLT 364
Query: 52 ---RKSDNEGRKHR--SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSE 106
R+S + H S R + RH S + +H +H S D+ ER +
Sbjct: 365 PPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRH---DHERTSQSHDRRHERREDTR 421
Query: 107 NGEDRHK--RKERKSSRGRSHSRSR--------SRERRHRSRSRERKKSRSR--SRERKK 154
DR K R+ER+ + +S SR R+RR +R+R++ R R+ ++
Sbjct: 422 GKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSRE 481
Query: 155 SRSRSRERKKSR----SRS-------RERKRRIRSR--------SRSRSR-HRHRTRSRS 194
R SR+ K+SR SRS R+R+ R R SRS R H SR+
Sbjct: 482 MRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRT 541
Query: 195 RTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 224
R+ SR+ + + R RS R P P
Sbjct: 542 EIRNESRNESRSEIRNDRMGRSRGRVPELP 571
Score = 55.8 bits (133), Expect = 7e-08
Identities = 44/168 (26%), Positives = 76/168 (45%), Gaps = 12/168 (7%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRS-RSRERKRKSDNEGRKHRS 63
D + G TS DR + S SP + + +SRS S SR+R ++
Sbjct: 1252 DQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQE---------- 1301
Query: 64 RSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 123
R R + R E + + +++ + + DK+ ++ R+RL E +R KR++ R R
Sbjct: 1302 RDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERER 1361
Query: 124 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRE 171
S S R+ R R R R + S+ S +R +++ + S SR+
Sbjct: 1362 LISDSVERD-RDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRD 1408
Score = 52.0 bits (123), Expect = 1e-06
Identities = 69/291 (23%), Positives = 113/291 (38%), Gaps = 62/291 (21%)
Query: 23 KKEQSEVSVSPRASKHHYSRSRSRSRERKR--KSDNEGRKHRSRS--------RSKEGRR 72
KKE S V + S R S+S +RK KS + +K R S + + +
Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKT 253
Query: 73 HESKDKS----------------SKKHKSEEHNDKEHSSDK---GRERLNSSENGEDRHK 113
++SK K KK+K E++ K+ +K G++R E ++
Sbjct: 254 NQSKKKGPRTPSPPPPIPEDIALGKKYK-EKYKVKDRIEEKTRDGKDRGRDFERQREKRD 312
Query: 114 RKERKSSRGRSHSRSRSRER----------RHRSRSRERKKSRSRSRER------KKSRS 157
+ S G+ HS SR + S S RK++ S S +R ++S S
Sbjct: 313 KPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSAS 372
Query: 158 RSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSR--------SRDRKKRIEK 209
S + ++ R RS R + RH H S+S R RDR+K +
Sbjct: 373 PYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSRE 432
Query: 210 PRRFSRSLSRT------PSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 254
R + + S + P R R A D ++ R L ++ +++ RE
Sbjct: 433 EREYEQDQSSSRDHRDDREPRDGRDRRDARDTRD--RRELRDSRDMRDSRE 481
Score = 45.8 bits (107), Expect = 8e-05
Identities = 47/214 (21%), Positives = 86/214 (40%), Gaps = 56/214 (26%)
Query: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR----------SRSRS-- 67
+ KK+ ++E S SPR S R S + D++ KHR SRS S
Sbjct: 821 KSKKRYRNEGSPSPRQSPKR-RREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879
Query: 68 ----------KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDR------ 111
KE R + +SS++++ +E +K S DK RE+ E+ R
Sbjct: 880 HLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIG 939
Query: 112 HKRKERKSSRGRSHSRSRSRERRHRSRSRERK---------------------------K 144
H + E + + R+H ++ + + + +++K K
Sbjct: 940 HHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQK 999
Query: 145 SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS 178
+S ++RKKS+ S + ++ ++KR R+
Sbjct: 1000 KKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRT 1033
Score = 38.9 bits (89), Expect = 0.009
Identities = 40/160 (25%), Positives = 60/160 (37%), Gaps = 19/160 (11%)
Query: 7 ERDGLAPEKTSPDR-------DKKKEQSEVS-------VSPRASKHHYSRSRSRSRE--R 50
E L+P + DR D+K E+ E S + + S R ++ E R
Sbjct: 872 ESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSR 931
Query: 51 KRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGED 110
R D G H+S R R H+ K +K K KE D G ER N ED
Sbjct: 932 MRAQDIIGH-HQSEDRETSDRAHDENKKKAKIQKKPIKKKKE--DDVGIERGNIETTSED 988
Query: 111 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSR 150
+K + +S + R + + S E +S+ +
Sbjct: 989 GQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKK 1028
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 100 bits (249), Expect = 3e-21
Identities = 73/236 (30%), Positives = 122/236 (51%), Gaps = 21/236 (8%)
Query: 41 SRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRE 100
SRS+ + + R+R S + R+ SR K GR+ SK +S S + + HS D+ R
Sbjct: 12 SRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSW----SRDLQPRSHSYDRRRR 67
Query: 101 RLNSSENGEDRHKRKERKSSRGRSHS----RSRSRERRHRSRSRERKKSRSRSRER---K 153
+SS + +++ R SRGR S RSRS+ R RSRSR R +S SRS ER +
Sbjct: 68 HRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHR 127
Query: 154 KSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRF 213
++RSRSR+R++ + R +E++ + + + + + H + R S + K +E
Sbjct: 128 RTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIK-------RGESGNIKAGLEHLPPA 180
Query: 214 SRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ-QEIAA 268
++ +R A +A +A R E AK+ +E+ + +VE+ K+ +EI A
Sbjct: 181 EQAKARLQL--VLEAAAKADEALKAKERNEEEAKRRKEEDQATLVEQVKRVKEIEA 234
Score = 95.9 bits (237), Expect = 6e-20
Identities = 81/235 (34%), Positives = 114/235 (48%), Gaps = 23/235 (9%)
Query: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG-RSHSRS 128
GRR ++ S+ + ++H + SS R S + G + + K R SR + S S
Sbjct: 2 GRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHS 61
Query: 129 RSRERRHRSRSRE-----RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183
R RRHRS S RK+SRSRSR R KS R R KSR+R + R+RS SRS
Sbjct: 62 YDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSS 121
Query: 184 SRHRH-RTRSRSRTRSR--SRDRKKRIEKPR-----RFSRSLSRTPSPPPFRGRNTAMDA 235
R H RTRSRSR R R RD++KR EK + + ++ R S G A
Sbjct: 122 ERSSHRRTRSRSRDRERRKGRDKEKR-EKEKDKGKDKELHNIKRGESGNIKAGLEHLPPA 180
Query: 236 QEALARR---LERAKKLQE-----QREKEMVEKQKQQEIAAAAATGGSVLNVAAL 282
++A AR LE A K E +R +E +++K+++ A V + A+
Sbjct: 181 EQAKARLQLVLEAAAKADEALKAKERNEEEAKRRKEEDQATLVEQVKRVKEIEAI 235
Score = 66.6 bits (161), Expect = 4e-11
Identities = 65/292 (22%), Positives = 119/292 (40%), Gaps = 29/292 (9%)
Query: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
E+ S + KKK + S S + YSR + R+ + KS + R + RS S + RR
Sbjct: 9 EEESRSKRKKKHRRRSSSSSSSDSRTYSRKKG-GRKSRSKSRSWSRDLQPRSHSYD-RRR 66
Query: 74 ESKDKSSKKHKSEEHNDKEHSSDKG---RERLNSSENGEDRHKRKERKSSRGRSHSRSRS 130
+ SS + S + S +G R + + S++ R + + R S RS RS
Sbjct: 67 RHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSH 126
Query: 131 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 190
R R RSR RER+K R + + RE++K + + +E R S +
Sbjct: 127 RRTRSRSRDRERRKGRDKEK---------REKEKDKGKDKELHNIKRGESGNIKAGLEHL 177
Query: 191 RSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQ 250
+ ++R + + K ++ R + + Q L +++R K+++
Sbjct: 178 PPAEQAKARLQLVLEAAAKADEALKAKERNEE----EAKRRKEEDQATLVEQVKRVKEIE 233
Query: 251 E-----------QREKEMVEKQKQQEIAAAAATGGSVLNVAALLASGTQVTP 291
+ KE+ + + E+ A +T G VA ++ ++ P
Sbjct: 234 AIESDSFVQQTFRSSKEVKKSVEPSEVKQATSTSGPASAVADPPSTEKEIDP 285
Score = 52.4 bits (124), Expect = 8e-07
Identities = 49/223 (21%), Positives = 90/223 (40%), Gaps = 9/223 (4%)
Query: 11 LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRE-RKRKSDNEGRKHRSRSRSKE 69
L P S DR ++ S S K SRSR R + R ++S ++ R RSRSR +
Sbjct: 55 LQPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRL 114
Query: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRE-RLNSSENGEDR--HKRKERKSSRGRSHS 126
S ++SS + D+E + +E R + G+D+ H K +S ++
Sbjct: 115 RSHSRSSERSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGESGNIKAGL 174
Query: 127 RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR-----ERKRRIRSRSR 181
+ ++R + ++ +++ E K++ R+ E K R E+ +R++
Sbjct: 175 EHLPPAEQAKARLQLVLEAAAKADEALKAKERNEEEAKRRKEEDQATLVEQVKRVKEIEA 234
Query: 182 SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 224
S + RS + +++ S S PP
Sbjct: 235 IESDSFVQQTFRSSKEVKKSVEPSEVKQATSTSGPASAVADPP 277
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 100 bits (249), Expect = 3e-21
Identities = 73/164 (44%), Positives = 96/164 (58%), Gaps = 21/164 (12%)
Query: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
ED+ + R+S G SRSRSR RR RSRSR R+ SRSRSR KSRSRSR R K RSR
Sbjct: 180 EDKPRTSHRRSYSG---SRSRSRSRR-RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
Query: 169 SRERKRRIRSRSRS-----RSRHRH-RTRS-----RSRTRSRSRDRKKRIE---KPRRFS 214
SR + R+ RS+S+S R H H R+RS +SR+RSRSR K+ + K + S
Sbjct: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS 295
Query: 215 RSLSRTPSP---PPFRGRNTAMDAQEALARRLERAKKLQEQREK 255
RS SR+ SP PP + R+ + + A +R R++ R +
Sbjct: 296 RSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSR 339
Score = 92.4 bits (228), Expect = 7e-19
Identities = 67/178 (37%), Positives = 87/178 (48%), Gaps = 22/178 (12%)
Query: 33 PRAS-KHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDK 91
PR S + YS SRSRSR R+R R RSRSRS R S+ +S + +S K
Sbjct: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242
Query: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRG-RSHSRSRSRERRHRSRSRERKKSRSRSR 150
S K + KS RG SHSRSRS++ +SRSR R +S +
Sbjct: 243 SRSKSKSKP-----------------KSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENG 285
Query: 151 E---RKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205
+ + KSRSRS+ R S K R S R+ R R+RSRS++RSRSR +
Sbjct: 286 KGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
Score = 87.4 bits (215), Expect = 2e-17
Identities = 61/165 (36%), Positives = 87/165 (52%), Gaps = 11/165 (6%)
Query: 49 ERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKS---EEHNDKEHSSDKGRERLNSS 105
E K ++ + SRSRS+ RR S+ + S + +S + + S KGR R S
Sbjct: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
Query: 106 ENGEDRHKRKERKSSRG-RSHSRSRSRERRHRSRSRERKKS-RSRSRERKKSRSRSRERK 163
+ + KS RG SHSRSRS++ +SRSR R +S + + KS+SRSR +
Sbjct: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS 299
Query: 164 KSRSRSRERKRRIRS------RSRSRSRHRHRTRSRSRTRSRSRD 202
+S S + RS R+ SRSR R R++SRSR+RS SRD
Sbjct: 300 RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 82.8 bits (203), Expect = 6e-16
Identities = 57/165 (34%), Positives = 80/165 (48%), Gaps = 4/165 (2%)
Query: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
E K ++S + + S + R R S R K R SR RS RSRSR +
Sbjct: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
Query: 134 RHRSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192
+SRS+ + K +S SRSRS+ E +KSRSRSR R + + +S+ R R++S
Sbjct: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS 299
Query: 193 RSRTRSRSRDRKKRIEKP---RRFSRSLSRTPSPPPFRGRNTAMD 234
RS + K R P R SRS SR+ S R R+++ D
Sbjct: 300 RSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 82.0 bits (201), Expect = 9e-16
Identities = 57/154 (37%), Positives = 80/154 (51%), Gaps = 10/154 (6%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKR---KSDNEGRKHRSRSRSKEGRRH 73
S R +++ +S S R+ S+SRSRSR R + +S ++GRK RS+S+SK
Sbjct: 196 SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKP---- 251
Query: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNS-SENGEDRHKRKERKSSRGRSHSRSRSRE 132
D+ S H D E+ + R R S ENG+ K K R S+ RS+S
Sbjct: 252 -KSDRGSHSHSRSRSKD-EYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPP 309
Query: 133 RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSR 166
+ RS S K++ SRSR R +S+SRSR R SR
Sbjct: 310 SKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSR 343
Score = 80.1 bits (196), Expect = 4e-15
Identities = 58/173 (33%), Positives = 85/173 (49%), Gaps = 14/173 (8%)
Query: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-R 134
+DK H+ + +S + R R R + R S +S SRSRSR + R
Sbjct: 180 EDKPRTSHR------RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGR 233
Query: 135 HRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS-RSRHRHRTRSR 193
RSRS+ R KSRS+S+ + KS S +SRS+ K R RSRSRS + + +S+
Sbjct: 234 SRSRSKGR-KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSK 292
Query: 194 SRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERA 246
SR+RS+SR P S +R+ SPPP R + + + +R R+
Sbjct: 293 SRSRSQSRS-----NSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRS 340
Score = 34.3 bits (77), Expect = 0.23
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 174 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAM 233
R I + R+ S R + SRSR+RSR R R + R SRS+S++ S R + +
Sbjct: 177 RLIEDKPRT-SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
Query: 234 DAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
+ R + K + R + + ++
Sbjct: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKD 267
Score = 34.3 bits (77), Expect = 0.23
Identities = 40/134 (29%), Positives = 52/134 (38%), Gaps = 30/134 (22%)
Query: 8 RDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRS 67
R + K+ P D+ S S + SRSRSRS + K D K +SRSRS
Sbjct: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGD---IKSKSRSRS 297
Query: 68 KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 127
+ R + K +S K R +SR RS SR
Sbjct: 298 -QSRSNSPLPVPPSKARSVSPPPK-------------------------RATSRSRSRSR 331
Query: 128 SRSRERRHRSRSRE 141
S+SR R RS SR+
Sbjct: 332 SKSRS-RSRSSSRD 344
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 100 bits (248), Expect = 3e-21
Identities = 72/227 (31%), Positives = 110/227 (48%), Gaps = 18/227 (7%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
+ E+ G + +S S S S YS S SR R S + +K SR
Sbjct: 501 EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSR 560
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
SRS + S+ +S + E N + K R+R S+ N +R +R+ R SR R
Sbjct: 561 SRSPTIKARRSRSRSYSRRIKIESN---RARVKIRDRRRSNRNSIERERRRNRSPSRERR 617
Query: 125 HSRSRSRERR----HRSRSRERKK------SRSRSRERKKSRSRSRERKKSRSRSRERKR 174
SRSRSR+RR RSRSR+R+K + S + + K ++ +ERKK RSRS ++ R
Sbjct: 618 RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDR 677
Query: 175 RIRSRSRSRSRHRHRTRSRSRTR----SRSRDR-KKRIEKPRRFSRS 216
+ + + R R + + + + + + S DR K++ E R FSRS
Sbjct: 678 KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRS 724
Score = 89.7 bits (221), Expect = 5e-18
Identities = 59/183 (32%), Positives = 89/183 (48%), Gaps = 23/183 (12%)
Query: 53 KSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH 112
K +++ ++ + RSRS S S S + +SS G R +S + R
Sbjct: 496 KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
Query: 113 KRKER------KSSRGRSHSRSR-----SRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161
KR R K+ R RS S SR S R + R R R S RER+++RS SRE
Sbjct: 556 KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRE 615
Query: 162 RKKSRSRSRERKRRIRSRSRSRSRHR------------HRTRSRSRTRSRSRDRKKRIEK 209
R++SRSRSR+R+ SRSRSR R + H+ + ++ + R ++R + I+K
Sbjct: 616 RRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDK 675
Query: 210 PRR 212
R+
Sbjct: 676 DRK 678
Score = 83.6 bits (205), Expect = 3e-16
Identities = 79/268 (29%), Positives = 132/268 (49%), Gaps = 33/268 (12%)
Query: 21 DKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSS 80
+++K+Q+E V+ ++ + S S R++D + + R+ ++ E K +
Sbjct: 442 EEEKQQTE-RVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHK 500
Query: 81 KKHKSEEHNDKEHSSDKGRERLNS-SENGEDRHKRKERKSSRGRSHSRSRS-----RERR 134
+K K + + SS G NS + + SS G S + SRS ++R
Sbjct: 501 EKEK--QGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRH 558
Query: 135 HRSRSRERKKSRSRSR--------ERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRH 186
RSRS K RSRSR E ++R + R+R++S S ER+RR R+RS SR R
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERR-RNRSPSRERR 617
Query: 187 RHRTRSRSR-----TRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALAR 241
R R+RSR R +RSRSRDR+K ++ S + + +G + ++ +R
Sbjct: 618 RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHK------HKGEAKEQERKKERSR 671
Query: 242 RLER-AKKLQEQREKEM---VEKQKQQE 265
+++ KK ++RE+E EKQK++E
Sbjct: 672 SIDKDRKKKDKEREREQDKRKEKQKREE 699
Score = 78.2 bits (191), Expect = 1e-14
Identities = 54/196 (27%), Positives = 94/196 (47%), Gaps = 18/196 (9%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
SP R++++ +S S R ++ SRSR R + ++ + G H+ + +KE R + +
Sbjct: 611 SPSRERRRSRSR-SRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
Query: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENG---EDRHKRKERKSSRGRSHSRSRS--- 130
+S K + ++ ++E DK +E+ E + R +RK R+ SRS S
Sbjct: 670 SRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISV 729
Query: 131 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS------ 184
+ RH SR +K + S++ S S R +S S+E+K + SRSRS
Sbjct: 730 KIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQR 789
Query: 185 -----RHRHRTRSRSR 195
+H+++SRSR
Sbjct: 790 SGKKASRKHKSKSRSR 805
Score = 75.9 bits (185), Expect = 7e-14
Identities = 66/264 (25%), Positives = 124/264 (46%), Gaps = 23/264 (8%)
Query: 16 TSPDRDKK--KEQSEVSVSPRASKHHYSR--------SRSRSRERKRKSDN----EGRKH 61
+SP R K+ + +S + R+ YSR +R + R+R+R + N E R++
Sbjct: 550 SSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRN 609
Query: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
RS SR + R S+D+ + + D+ D+ +S + K +ERK R
Sbjct: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
Query: 122 GRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR 181
RS + R ++ + R R ++++K + + RE K + S++ + R R ER RS S
Sbjct: 670 SRSIDKDRKKKDKEREREQDKRKEKQK-REEKDFKFSSQDDRLKRKRESERTFS-RSGSI 727
Query: 182 SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGR-NTAMDAQEALA 240
S RH +R S+ +S ++D KK S S R+ S P + A + + +
Sbjct: 728 SVKIIRHDSRQDSK-KSTTKDSKK-----HSGSDSSGRSSSESPGSSKEKKAKKPKHSRS 781
Query: 241 RRLERAKKLQEQREKEMVEKQKQQ 264
R +E++++ ++ ++ K + +
Sbjct: 782 RSVEKSQRSGKKASRKHKSKSRSR 805
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSR------SRSRERKRKSDNEGRK 60
E++ S D+D+KK+ E K R S+ KRK ++E
Sbjct: 662 EQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTF 721
Query: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
RS S S + RH+S+ S KS + K+HS R +S G + K+ ++
Sbjct: 722 SRSGSISVKIIRHDSRQDSK---KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKP-- 776
Query: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152
HSRSRS E+ RS + +K +S+SR R
Sbjct: 777 ---KHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 39.3 bits (90), Expect = 0.007
Identities = 41/203 (20%), Positives = 87/203 (42%), Gaps = 11/203 (5%)
Query: 66 RSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 125
RS G D +H+ + + +K ++ L+ + E++ ++ ER + +
Sbjct: 400 RSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEK-QQTERVT---KEM 455
Query: 126 SRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185
+ +E+ S R+ E+K++ + + + + +E++++ RSRS S S
Sbjct: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSS 515
Query: 186 HRHRTRSRSRTRSRSRD-RKKRIEKPRRFSRSLSRTPSPP----PFRGRNTAMDAQEALA 240
+ S SRT S S SR+ SR+ SP R R+ + A+ + +
Sbjct: 516 GS--SSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRS 573
Query: 241 RRLERAKKLQEQREKEMVEKQKQ 263
R R K++ R + + +++
Sbjct: 574 RSYSRRIKIESNRARVKIRDRRR 596
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 100 bits (248), Expect = 3e-21
Identities = 72/227 (31%), Positives = 110/227 (48%), Gaps = 18/227 (7%)
Query: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
+ E+ G + +S S S S YS S SR R S + +K SR
Sbjct: 501 EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSR 560
Query: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
SRS + S+ +S + E N + K R+R S+ N +R +R+ R SR R
Sbjct: 561 SRSPTIKARRSRSRSYSRRIKIESN---RARVKIRDRRRSNRNSIERERRRNRSPSRERR 617
Query: 125 HSRSRSRERR----HRSRSRERKK------SRSRSRERKKSRSRSRERKKSRSRSRERKR 174
SRSRSR+RR RSRSR+R+K + S + + K ++ +ERKK RSRS ++ R
Sbjct: 618 RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDR 677
Query: 175 RIRSRSRSRSRHRHRTRSRSRTR----SRSRDR-KKRIEKPRRFSRS 216
+ + + R R + + + + + + S DR K++ E R FSRS
Sbjct: 678 KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRS 724
Score = 89.7 bits (221), Expect = 5e-18
Identities = 59/183 (32%), Positives = 89/183 (48%), Gaps = 23/183 (12%)
Query: 53 KSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH 112
K +++ ++ + RSRS S S S + +SS G R +S + R
Sbjct: 496 KKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
Query: 113 KRKER------KSSRGRSHSRSR-----SRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161
KR R K+ R RS S SR S R + R R R S RER+++RS SRE
Sbjct: 556 KRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRE 615
Query: 162 RKKSRSRSRERKRRIRSRSRSRSRHR------------HRTRSRSRTRSRSRDRKKRIEK 209
R++SRSRSR+R+ SRSRSR R + H+ + ++ + R ++R + I+K
Sbjct: 616 RRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDK 675
Query: 210 PRR 212
R+
Sbjct: 676 DRK 678
Score = 83.6 bits (205), Expect = 3e-16
Identities = 79/268 (29%), Positives = 132/268 (49%), Gaps = 33/268 (12%)
Query: 21 DKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSS 80
+++K+Q+E V+ ++ + S S R++D + + R+ ++ E K +
Sbjct: 442 EEEKQQTE-RVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHK 500
Query: 81 KKHKSEEHNDKEHSSDKGRERLNS-SENGEDRHKRKERKSSRGRSHSRSRS-----RERR 134
+K K + + SS G NS + + SS G S + SRS ++R
Sbjct: 501 EKEK--QGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRH 558
Query: 135 HRSRSRERKKSRSRSR--------ERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRH 186
RSRS K RSRSR E ++R + R+R++S S ER+RR R+RS SR R
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERR-RNRSPSRERR 617
Query: 187 RHRTRSRSR-----TRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALAR 241
R R+RSR R +RSRSRDR+K ++ S + + +G + ++ +R
Sbjct: 618 RSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHK------HKGEAKEQERKKERSR 671
Query: 242 RLER-AKKLQEQREKEM---VEKQKQQE 265
+++ KK ++RE+E EKQK++E
Sbjct: 672 SIDKDRKKKDKEREREQDKRKEKQKREE 699
Score = 78.2 bits (191), Expect = 1e-14
Identities = 54/196 (27%), Positives = 94/196 (47%), Gaps = 18/196 (9%)
Query: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
SP R++++ +S S R ++ SRSR R + ++ + G H+ + +KE R + +
Sbjct: 611 SPSRERRRSRSR-SRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
Query: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENG---EDRHKRKERKSSRGRSHSRSRS--- 130
+S K + ++ ++E DK +E+ E + R +RK R+ SRS S
Sbjct: 670 SRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISV 729
Query: 131 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS------ 184
+ RH SR +K + S++ S S R +S S+E+K + SRSRS
Sbjct: 730 KIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQR 789
Query: 185 -----RHRHRTRSRSR 195
+H+++SRSR
Sbjct: 790 SGKKASRKHKSKSRSR 805
Score = 75.9 bits (185), Expect = 7e-14
Identities = 66/264 (25%), Positives = 124/264 (46%), Gaps = 23/264 (8%)
Query: 16 TSPDRDKK--KEQSEVSVSPRASKHHYSR--------SRSRSRERKRKSDN----EGRKH 61
+SP R K+ + +S + R+ YSR +R + R+R+R + N E R++
Sbjct: 550 SSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRN 609
Query: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
RS SR + R S+D+ + + D+ D+ +S + K +ERK R
Sbjct: 610 RSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER 669
Query: 122 GRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR 181
RS + R ++ + R R ++++K + + RE K + S++ + R R ER RS S
Sbjct: 670 SRSIDKDRKKKDKEREREQDKRKEKQK-REEKDFKFSSQDDRLKRKRESERTFS-RSGSI 727
Query: 182 SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGR-NTAMDAQEALA 240
S RH +R S+ +S ++D KK S S R+ S P + A + + +
Sbjct: 728 SVKIIRHDSRQDSK-KSTTKDSKK-----HSGSDSSGRSSSESPGSSKEKKAKKPKHSRS 781
Query: 241 RRLERAKKLQEQREKEMVEKQKQQ 264
R +E++++ ++ ++ K + +
Sbjct: 782 RSVEKSQRSGKKASRKHKSKSRSR 805
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSR------SRSRERKRKSDNEGRK 60
E++ S D+D+KK+ E K R S+ KRK ++E
Sbjct: 662 EQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTF 721
Query: 61 HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120
RS S S + RH+S+ S KS + K+HS R +S G + K+ ++
Sbjct: 722 SRSGSISVKIIRHDSRQDSK---KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKP-- 776
Query: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152
HSRSRS E+ RS + +K +S+SR R
Sbjct: 777 ---KHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 39.3 bits (90), Expect = 0.007
Identities = 41/203 (20%), Positives = 87/203 (42%), Gaps = 11/203 (5%)
Query: 66 RSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSH 125
RS G D +H+ + + +K ++ L+ + E++ ++ ER + +
Sbjct: 400 RSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEK-QQTERVT---KEM 455
Query: 126 SRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185
+ +E+ S R+ E+K++ + + + + +E++++ RSRS S S
Sbjct: 456 NEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSS 515
Query: 186 HRHRTRSRSRTRSRSRD-RKKRIEKPRRFSRSLSRTPSPP----PFRGRNTAMDAQEALA 240
+ S SRT S S SR+ SR+ SP R R+ + A+ + +
Sbjct: 516 GS--SSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRS 573
Query: 241 RRLERAKKLQEQREKEMVEKQKQ 263
R R K++ R + + +++
Sbjct: 574 RSYSRRIKIESNRARVKIRDRRR 596
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 95.9 bits (237), Expect = 6e-20
Identities = 80/241 (33%), Positives = 112/241 (46%), Gaps = 29/241 (12%)
Query: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73
+++S + + S S AS H + + + ++ G +H SRSRS+ GRRH
Sbjct: 802 KRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEH-SRSRSRSGRRH 860
Query: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR-----SHSRS 128
S +SS++ S + S R+R S ++ D R R S R ++ S
Sbjct: 861 -SSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASS 919
Query: 129 RSRERRHR----------SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS 178
+ R +RH+ S S+ R +SRS +RER +SR RSR SRSRS+ R R +
Sbjct: 920 KHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA 979
Query: 179 RSRSRSRHRHRTRSRS----RTRSRSRDRKKRIEKP-------RRFSRS-LSRTPSPPPF 226
S RSR R RSRS RS SR R E P R F RS + R+ SP F
Sbjct: 980 HSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYF 1039
Query: 227 R 227
R
Sbjct: 1040 R 1040
Score = 75.5 bits (184), Expect = 9e-14
Identities = 77/290 (26%), Positives = 123/290 (42%), Gaps = 34/290 (11%)
Query: 2 AASDTERDGLAPE-----KTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDN 56
A +D+ER G PE +P R +++ Q + ++ S + D+
Sbjct: 723 APADSER-GPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDH 781
Query: 57 EGRKHRSR-SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK 115
GRKH+ S RR +K S H+S+ + E S D RL+ + ++ +
Sbjct: 782 GGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLH--QKSPSQYSEE 839
Query: 116 ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRS-RSRERK---KSRSRSRE 171
E + G HSRSRSR R S R ++S S S + +S SR+R S S +
Sbjct: 840 EEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSD 899
Query: 172 RKRRIRSRSR-------SRSRHRHRTR-------------SRSRTRSRSRDRKKRIEKPR 211
R RR RS + S+HR + S+SR+RSRS R++ + R
Sbjct: 900 RSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGR 959
Query: 212 RFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQ 261
S S SR+ S R TA Q + + +R++ + ++ K+
Sbjct: 960 SRSSSCSRSRSKRRSRS-TTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKR 1008
Score = 51.2 bits (121), Expect = 2e-06
Identities = 57/233 (24%), Positives = 86/233 (36%), Gaps = 26/233 (11%)
Query: 10 GLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKE 69
G E T KKE+S S + K H +S +RK K+D E + ++ S K
Sbjct: 652 GSETEDTGRSLPSKKERSGKSHRHKKKKKH---KKSSKHKRKHKADTEEKSSKAESGEKS 708
Query: 70 GRRHESKDKSSKKHKSEEHNDKEH----------SSDKGRERLNSSENGEDRHKRKERKS 119
+R K + KK+KS D E S R R + ++ + R E S
Sbjct: 709 KKR---KKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGS 765
Query: 120 SRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER------K 173
S + S + H R + + S + R ++ SR +S+ S +
Sbjct: 766 SGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASS 825
Query: 174 RRIRSRSRSRSRHRHRTRS----RSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 222
R+ +S S+ SR+RSRS R RR S S S
Sbjct: 826 HRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASS 878
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/191 (19%), Positives = 70/191 (36%), Gaps = 9/191 (4%)
Query: 33 PRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKE 92
P S + RS K++ + +H+ + + K+ +H+ K K+ + KS + E
Sbjct: 647 PGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGE 706
Query: 93 HSSD-KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 151
S K R+R + + +R + G R RR + S+ R
Sbjct: 707 KSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSS 766
Query: 152 RKK--------SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDR 203
KK S+ + K +RR ++ SRS HR + S +
Sbjct: 767 GKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSH 826
Query: 204 KKRIEKPRRFS 214
+ + P ++S
Sbjct: 827 RLHQKSPSQYS 837
Score = 46.6 bits (109), Expect = 4e-05
Identities = 39/184 (21%), Positives = 72/184 (39%), Gaps = 25/184 (13%)
Query: 68 KEGRRHESKDKSSKKHKSEEHNDKEH-----------SSDKGRERLNSSENGEDRHKRKE 116
K R +++ K ++K K + K+H S + G E++ S G
Sbjct: 577 KLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASG 636
Query: 117 ------RKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
K G SH R +ER R +++KK + S+ ++K ++ +
Sbjct: 637 SACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTE 696
Query: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
E+ + S +S+ R + + + + +R + E P S +P+PP R R
Sbjct: 697 EKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPG------SGSPAPP--RRRR 748
Query: 231 TAMD 234
A D
Sbjct: 749 RAQD 752
Score = 36.2 bits (82), Expect = 0.060
Identities = 43/161 (26%), Positives = 61/161 (37%), Gaps = 13/161 (8%)
Query: 5 DTERDGLAPEKTSPDRDK-KKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRS 63
D++ A K R K + S+S S+ SRS +R R R R GR S
Sbjct: 910 DSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSR-SRSHTRERSRSR-----GRSRSS 963
Query: 64 R-SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
SRS+ RR S S + D+ S+ +R S + +ER S R
Sbjct: 964 SCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGR- 1022
Query: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK 163
R R + +RS+S +S KK R + K
Sbjct: 1023 ----RDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSK 1059
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.120 0.319
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,682,728
Number of Sequences: 37866
Number of extensions: 732376
Number of successful extensions: 39162
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 752
Number of HSP's successfully gapped in prelim test: 831
Number of HSP's that attempted gapping in prelim test: 7700
Number of HSP's gapped (non-prelim): 10046
length of query: 434
length of database: 18,247,518
effective HSP length: 105
effective length of query: 329
effective length of database: 14,271,588
effective search space: 4695352452
effective search space used: 4695352452
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.