BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38045928 43 kD receptor-associated protein of the synapse isoform 2 [Homo sapiens] (353 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|38045928 43 kD receptor-associated protein of the synapse iso... 722 0.0 gi|15619013 43 kD receptor-associated protein of the synapse iso... 654 0.0 gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 77 2e-14 gi|224548927 G-protein signaling modulator 1 (AGS3-like, C. eleg... 59 7e-09 gi|224548925 G-protein signaling modulator 1 (AGS3-like, C. eleg... 59 7e-09 gi|164519122 LGN protein [Homo sapiens] 57 3e-08 gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens] 42 0.001 gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 40 0.002 gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 40 0.002 gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 40 0.002 gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] 40 0.003 gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] 40 0.003 gi|34452686 ring finger protein, LIM domain interacting [Homo sa... 39 0.007 gi|34452684 ring finger protein, LIM domain interacting [Homo sa... 39 0.007 gi|150170725 zinc and ring finger 4 [Homo sapiens] 39 0.009 gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 38 0.012 gi|58331195 ring finger and CHY zinc finger domain containing 1 ... 37 0.020 gi|21071001 autocrine motility factor receptor [Homo sapiens] 37 0.020 gi|4503729 FK506 binding protein 52 [Homo sapiens] 37 0.027 gi|5031825 ring finger protein 103 [Homo sapiens] 37 0.035 gi|37595553 ring finger protein 111 [Homo sapiens] 37 0.035 gi|188497705 BRCA1 associated protein [Homo sapiens] 36 0.046 gi|32454739 tripartite motif-containing 3 [Homo sapiens] 36 0.046 gi|32454737 tripartite motif-containing 3 [Homo sapiens] 36 0.046 gi|7706039 ring finger protein 181 [Homo sapiens] 36 0.046 gi|27436927 synoviolin 1 isoform b [Homo sapiens] 36 0.060 gi|27436925 synoviolin 1 isoform a [Homo sapiens] 36 0.060 gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 36 0.060 gi|239749332 PREDICTED: hypothetical protein XP_002347002 [Homo ... 35 0.078 gi|239743424 PREDICTED: hypothetical protein XP_002342853 [Homo ... 35 0.078 >gi|38045928 43 kD receptor-associated protein of the synapse isoform 2 [Homo sapiens] Length = 353 Score = 722 bits (1864), Expect = 0.0 Identities = 353/353 (100%), Positives = 353/353 (100%) Query: 1 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK Sbjct: 1 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60 Query: 61 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ Sbjct: 61 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120 Query: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE Sbjct: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180 Query: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG Sbjct: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240 Query: 241 DRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEET 300 DRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEET Sbjct: 241 DRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEET 300 Query: 301 ELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 353 ELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV Sbjct: 301 ELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 353 >gi|15619013 43 kD receptor-associated protein of the synapse isoform 1 [Homo sapiens] Length = 412 Score = 654 bits (1686), Expect = 0.0 Identities = 335/412 (81%), Positives = 343/412 (83%), Gaps = 59/412 (14%) Query: 1 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK Sbjct: 1 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60 Query: 61 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ Sbjct: 61 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120 Query: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE Sbjct: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180 Query: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG Sbjct: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240 Query: 241 DRPLQALCLLCFADIHRSRGDLE---------------------------------LSQL 267 DRPLQALCLLCFADIHRSRGDLE +++ Sbjct: 241 DRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARK 300 Query: 268 KLHCLSESIYRSKGLQREL--------------------------RAHVVRFHECVEETE 301 L ++I R++ L E+ RAHVVRFHECVEETE Sbjct: 301 ALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETE 360 Query: 302 LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 353 LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV Sbjct: 361 LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 412 >gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] Length = 2481 Score = 77.0 bits (188), Expect = 2e-14 Identities = 58/239 (24%), Positives = 110/239 (46%), Gaps = 13/239 (5%) Query: 38 DLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLC 97 D+ G +V L AH +G Y+E +K+ + A++L D ++Y NL + + L Sbjct: 629 DMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALL 688 Query: 98 EFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNND 157 F K K L L + +Q + ++G+ F+ A++ +E+ L AH Sbjct: 689 NFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVK 748 Query: 158 DAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYR 217 D LE +LG+ Y ++ Y+KAL + + E+ Y + L + H+A Y Sbjct: 749 DRRLEASAYAALGTAYRMIQKYDKALGYHTQELEV---YQELSDLPGECRAHGHLAAVYM 805 Query: 218 LLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESI 276 LG+ A +C EE + + + D L+A + G++ ++++ ++ + E+I Sbjct: 806 ALGKYTMAFKCYEEQLDLGQKLKDPSLEA----------QVYGNMGITKMNMNVMEEAI 854 Score = 60.8 bits (146), Expect = 2e-09 Identities = 56/263 (21%), Positives = 115/263 (43%), Gaps = 13/263 (4%) Query: 23 EKALQVWTKVLE---KSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDA 79 +KAL T+ LE + SDL G R G L + +G+Y K Q+D ++L+D Sbjct: 771 DKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDP 830 Query: 80 DFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQL---GGQVSLSMGNAFLGL 136 + Y N+ + + + I Y + L + +G + G+ ++G+ + L Sbjct: 831 SLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEAL 890 Query: 137 SVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNY 196 +++A++ +E+ L A + + + + LG+ + + ++AL K + + Sbjct: 891 GDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHEL 950 Query: 197 GKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIH 256 G+ ++ +A + + + LG A+ C E + IA DR L++ ++ Sbjct: 951 GEAFN---KAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVY 1007 Query: 257 RSRGD----LELSQLKLHCLSES 275 + G+ L+ QL L E+ Sbjct: 1008 QQMGEYDTALQYHQLDLQIAEET 1030 Score = 55.8 bits (133), Expect = 6e-08 Identities = 62/269 (23%), Positives = 119/269 (44%), Gaps = 13/269 (4%) Query: 22 TEKA---LQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELED 78 TEK+ +Q V + D G R G L +A G Y+E L Q+ A +L+D Sbjct: 250 TEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKD 309 Query: 79 ADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSV 138 + + +L + ++ ++ K C+ L + +MG ++ + Sbjct: 310 REAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGD 369 Query: 139 FQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGK 198 F+ A++ E+ L+ A + + E R +LGS Y ++++KA+ + EL + Sbjct: 370 FENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELME 429 Query: 199 GWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRS 258 +++ RA + + A R + L A + E+ + IA DR + IH+ Sbjct: 430 K-AIEMRAYA--GLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQM 486 Query: 259 RGDLELSQLKLH----CLSESI--YRSKG 281 +GD + + LKLH C+++ + Y ++G Sbjct: 487 KGDYD-TALKLHKTHLCIAQELSDYAAQG 514 Score = 50.1 bits (118), Expect = 3e-06 Identities = 51/217 (23%), Positives = 91/217 (41%), Gaps = 11/217 (5%) Query: 34 EKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSN 93 ++S D + R LG + + MG ++ ++ + A++L + +Y NL + Sbjct: 345 KQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAY 404 Query: 94 EKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYA 153 F K +SY L L + + +G+A + ++A + E+ L A Sbjct: 405 HYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIA 464 Query: 154 HNNDDAMLECRVCCSLGSFYAQVKDYEKALFFP----CKAAELVNNYGKGWSLKYRAMSQ 209 + D E R +LG + DY+ AL C A EL + +G RA Sbjct: 465 EDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQG-----RAYG- 518 Query: 210 YHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQA 246 +M AY LG A++ + ++I+++ DR QA Sbjct: 519 -NMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQA 554 Score = 48.5 bits (114), Expect = 9e-06 Identities = 40/205 (19%), Positives = 93/205 (45%), Gaps = 3/205 (1%) Query: 32 VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91 + ++ SD + R G + A++ +G Y + +K+ ++ + E+ D ++ NLA Sbjct: 503 IAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAV 562 Query: 92 SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151 + + L + + + + L + Q + ++GN + +A +E+ LR Sbjct: 563 AYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLR 622 Query: 152 YAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYH 211 A + D E +VC +LG + + +Y++A+ + + L + S +A + + Sbjct: 623 LAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLS---QAKAYCN 679 Query: 212 MAVAYRLLGRLGSAMECCEESMKIA 236 + +A++ L A EC + + +A Sbjct: 680 LGLAFKALLNFSKAEECQKYLLSLA 704 Score = 47.0 bits (110), Expect = 3e-05 Identities = 41/199 (20%), Positives = 86/199 (43%), Gaps = 3/199 (1%) Query: 3 QDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRF---RVLGCLVTAHSEMGRY 59 QDQ K G ++AL + K L + +L F + G L + HS++G Y Sbjct: 914 QDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNY 973 Query: 60 KEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGA 119 ++ + Q++ AR+++D ++ L +++ E+ + Y + L + Sbjct: 974 EQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQIAEETNNP 1033 Query: 120 QLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDY 179 G+ ++G + L F++A+ E+ L A +D + SLG + +++Y Sbjct: 1034 TCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNY 1093 Query: 180 EKALFFPCKAAELVNNYGK 198 +A+ + + L G+ Sbjct: 1094 SQAVMYLQEGLRLAEQLGR 1112 Score = 42.0 bits (97), Expect = 8e-04 Identities = 41/214 (19%), Positives = 85/214 (39%), Gaps = 6/214 (2%) Query: 33 LEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARS 92 L + D +R LG H MG ++ L ++ A EL +A ++Y L Sbjct: 910 LNRMQDQAKAYRGLG---NGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSL 966 Query: 93 NEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRY 152 + +L + + IS + L + L + +G + + + AL+ + L+ Sbjct: 967 HSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQI 1026 Query: 153 AHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHM 212 A ++ + R +LG Y + +E+A+ + + + L + +S + Sbjct: 1027 AEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMN---DLAAKTVSYSSL 1083 Query: 213 AVAYRLLGRLGSAMECCEESMKIALQHGDRPLQA 246 + L A+ +E +++A Q G R +A Sbjct: 1084 GRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEA 1117 Score = 31.6 bits (70), Expect = 1.1 Identities = 34/187 (18%), Positives = 78/187 (41%), Gaps = 9/187 (4%) Query: 3 QDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGR------FRVLGCLVTAHSEM 56 +++ + G + +KA+ VLE + +LM + + LG ++ Sbjct: 391 REEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDL 450 Query: 57 GRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTR 116 R K+ + Q+ A +L+D + NL ++ ++ + KT L + Sbjct: 451 ERAKQ---YHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQEL 507 Query: 117 AGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQV 176 + G+ +MGNA+ L ++ +A++ + L+ + +D + +L Y + Sbjct: 508 SDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQAL 567 Query: 177 KDYEKAL 183 +++AL Sbjct: 568 GAHDRAL 574 Score = 29.3 bits (64), Expect = 5.6 Identities = 34/164 (20%), Positives = 60/164 (36%), Gaps = 37/164 (22%) Query: 120 QLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDY 179 +L G V ++ +A+ L +K+ ++ L A D ECR +LGS + +Y Sbjct: 231 KLRGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNY 290 Query: 180 EKA---------LFFPCKAAELVNNYGKGWSLKYRAMSQY-------------------- 210 +A L K E ++ Y A+ Y Sbjct: 291 REALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDE 350 Query: 211 --------HMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQA 246 +M Y +G +A++C E+ +KIA G++ +A Sbjct: 351 LSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEA 394 >gi|224548927 G-protein signaling modulator 1 (AGS3-like, C. elegans) isoform a [Homo sapiens] Length = 675 Score = 58.9 bits (141), Expect = 7e-09 Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 17/180 (9%) Query: 70 IDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSM 129 + +EL D +Y NL ++ L F + ++ K L + + ++ Sbjct: 196 LSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNL 255 Query: 130 GNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCK- 188 GNA + L F A E ++K L+ + D +E + C SLG+ Y ++DYE+A + + Sbjct: 256 GNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRH 315 Query: 189 ---AAELVNNYGKG---WSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDR 242 A EL + G+G WSL AY +GR A+ ++ ++I+ + GDR Sbjct: 316 LLIAQELADRVGEGRACWSL----------GNAYVSMGRPAQALTFAKKHLQISQEIGDR 365 Score = 53.9 bits (128), Expect = 2e-07 Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 3/193 (1%) Query: 32 VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91 ++++ D + R G L H +G + E F ++ A+E D +Y NL Sbjct: 198 LVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGN 257 Query: 92 SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151 ++ L F Y K L L + Q S+GN + L +++A E + L Sbjct: 258 AHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLL 317 Query: 152 YAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYH 211 A D + E R C SLG+ Y + +AL F K ++ G ++ + Sbjct: 318 IAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHG---ELTARMN 374 Query: 212 MAVAYRLLGRLGS 224 +A +LGRL S Sbjct: 375 VAQLQLVLGRLTS 387 Score = 39.3 bits (90), Expect = 0.005 Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 5/122 (4%) Query: 139 FQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGK 198 F+ + FE A++ +D + LG+ Y +K++ +AL + L G Sbjct: 44 FKTGVAFFEAAVQVG--TEDLKTLSAIYSQLGNAYFYLKEHGRALEYHKHDLLLARTIGD 101 Query: 199 GWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRS 258 A + ++ ++LGR A CC+ + IA + GD+ +A L +++ + Sbjct: 102 RMG---EAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQGDKVGEARALYNIGNVYHA 158 Query: 259 RG 260 +G Sbjct: 159 KG 160 >gi|224548925 G-protein signaling modulator 1 (AGS3-like, C. elegans) isoform b [Homo sapiens] Length = 457 Score = 58.9 bits (141), Expect = 7e-09 Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 17/180 (9%) Query: 70 IDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSM 129 + +EL D +Y NL ++ L F + ++ K L + + ++ Sbjct: 196 LSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNL 255 Query: 130 GNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCK- 188 GNA + L F A E ++K L+ + D +E + C SLG+ Y ++DYE+A + + Sbjct: 256 GNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRH 315 Query: 189 ---AAELVNNYGKG---WSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDR 242 A EL + G+G WSL AY +GR A+ ++ ++I+ + GDR Sbjct: 316 LLIAQELADRVGEGRACWSL----------GNAYVSMGRPAQALTFAKKHLQISQEIGDR 365 Score = 53.9 bits (128), Expect = 2e-07 Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 3/193 (1%) Query: 32 VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91 ++++ D + R G L H +G + E F ++ A+E D +Y NL Sbjct: 198 LVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGN 257 Query: 92 SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151 ++ L F Y K L L + Q S+GN + L +++A E + L Sbjct: 258 AHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLL 317 Query: 152 YAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYH 211 A D + E R C SLG+ Y + +AL F K ++ G ++ + Sbjct: 318 IAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHG---ELTARMN 374 Query: 212 MAVAYRLLGRLGS 224 +A +LGRL S Sbjct: 375 VAQLQLVLGRLTS 387 Score = 39.3 bits (90), Expect = 0.005 Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 5/122 (4%) Query: 139 FQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGK 198 F+ + FE A++ +D + LG+ Y +K++ +AL + L G Sbjct: 44 FKTGVAFFEAAVQVG--TEDLKTLSAIYSQLGNAYFYLKEHGRALEYHKHDLLLARTIGD 101 Query: 199 GWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRS 258 A + ++ ++LGR A CC+ + IA + GD+ +A L +++ + Sbjct: 102 RMG---EAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQGDKVGEARALYNIGNVYHA 158 Query: 259 RG 260 +G Sbjct: 159 KG 160 >gi|164519122 LGN protein [Homo sapiens] Length = 684 Score = 56.6 bits (135), Expect = 3e-08 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 9/194 (4%) Query: 4 DQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEML 63 ++ + ++ + Y+ N + ++ D + R G L H +G +++ + Sbjct: 172 EEVRDALQAAVDFYEENLS---------LVTALGDRAAQGRAFGNLGNTHYLLGNFRDAV 222 Query: 64 KFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGG 123 ++ A+E D +Y NL + L EF Y K L L + Sbjct: 223 IAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEA 282 Query: 124 QVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKAL 183 Q S+GN + L ++KA++ K L A +D + E R C SLG+ Y + ++++A+ Sbjct: 283 QSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAM 342 Query: 184 FFPCKAAELVNNYG 197 F K E+ G Sbjct: 343 HFAEKHLEISREVG 356 Score = 37.0 bits (84), Expect = 0.027 Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 12/140 (8%) Query: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180 L G+ G+ G+S F+ A++ +D + LG+ Y + DY Sbjct: 29 LEGERLCKSGDCRAGVSFFEAAVQV---------GTEDLKTLSAIYSQLGNAYFYLHDYA 79 Query: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240 KAL + L G A + ++ ++LG A+ CC+ + I+ + Sbjct: 80 KALEYHHHDLTLARTIGDQLG---EAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELN 136 Query: 241 DRPLQALCLLCFADIHRSRG 260 D+ +A L +++ ++G Sbjct: 137 DKVGEARALYNLGNVYHAKG 156 Score = 35.8 bits (81), Expect = 0.060 Identities = 55/254 (21%), Positives = 95/254 (37%), Gaps = 40/254 (15%) Query: 66 AVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLG-GQ 124 A VQ+ T ED L Y L + L ++ K + Y L L T G QLG + Sbjct: 49 AAVQVGT----EDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLART-IGDQLGEAK 103 Query: 125 VSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALF 184 S ++GN L F +A+ ++ L + +D + E R +LG+ Y + K Sbjct: 104 ASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVY-----HAKGKS 158 Query: 185 FPCKAAELVNNYGKGWSLKYRAMSQYH----------------------MAVAYRLLGRL 222 F C + V + + +A ++ + + LLG Sbjct: 159 FGCPGPQDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNF 218 Query: 223 GSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESIYRSKGL 282 A+ E+ + IA + GD+ + + + G+ E + SE ++ L Sbjct: 219 RDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETA-------SEYYKKTLLL 271 Query: 283 QRELRAHVVRFHEC 296 R+L+ V C Sbjct: 272 ARQLKDRAVEAQSC 285 Score = 31.6 bits (70), Expect = 1.1 Identities = 27/127 (21%), Positives = 51/127 (40%) Query: 32 VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91 + ++ D R L A+ +G ++ ++ + AR+L+D +S +L Sbjct: 231 IAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGN 290 Query: 92 SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151 + L ++ K I Y L + G+ S+GNA+ L +A+ EK L Sbjct: 291 TYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLE 350 Query: 152 YAHNNDD 158 + D Sbjct: 351 ISREVGD 357 Score = 31.2 bits (69), Expect = 1.5 Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 23 EKALQVWTK---VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDA 79 EKA+ K + ++ +D +G R L A++ +G + + + FA ++ +RE+ D Sbjct: 299 EKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDK 358 Query: 80 DFLLESYLNLA 90 L + LNL+ Sbjct: 359 SGELTARLNLS 369 >gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens] Length = 1208 Score = 41.6 bits (96), Expect = 0.001 Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 8/57 (14%) Query: 298 EETELYCGLCGESIGEKNSRLQALPCSHIFHLRC----LQNNGTRSCPNCRRSSMKP 350 EE E C +C E++ +N L LPC+H FH +C L GT CP CR + P Sbjct: 1142 EEEEEPCVICHENLSPEN--LSVLPCAHKFHAQCIRPWLMQQGT--CPTCRLHVLLP 1194 >gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] Length = 457 Score = 40.4 bits (93), Expect = 0.002 Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 8/87 (9%) Query: 81 FLLESYLNLARSNEKLCEFHKTISYCKTCLGL-PGTRAGAQLGGQVSLSMGNAFLGLSVF 139 FLL ++LNLA KL E+ K + C LGL G G+ L M F Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE-------F 367 Query: 140 QKALESFEKALRYAHNNDDAMLECRVC 166 + A FEK L N A L+ +C Sbjct: 368 ESAKGDFEKVLEVNPQNKAARLQISMC 394 >gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] Length = 457 Score = 40.4 bits (93), Expect = 0.002 Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 8/87 (9%) Query: 81 FLLESYLNLARSNEKLCEFHKTISYCKTCLGL-PGTRAGAQLGGQVSLSMGNAFLGLSVF 139 FLL ++LNLA KL E+ K + C LGL G G+ L M F Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE-------F 367 Query: 140 QKALESFEKALRYAHNNDDAMLECRVC 166 + A FEK L N A L+ +C Sbjct: 368 ESAKGDFEKVLEVNPQNKAARLQISMC 394 >gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] Length = 457 Score = 40.4 bits (93), Expect = 0.002 Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 8/87 (9%) Query: 81 FLLESYLNLARSNEKLCEFHKTISYCKTCLGL-PGTRAGAQLGGQVSLSMGNAFLGLSVF 139 FLL ++LNLA KL E+ K + C LGL G G+ L M F Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE-------F 367 Query: 140 QKALESFEKALRYAHNNDDAMLECRVC 166 + A FEK L N A L+ +C Sbjct: 368 ESAKGDFEKVLEVNPQNKAARLQISMC 394 >gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] Length = 744 Score = 40.0 bits (92), Expect = 0.003 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 9/59 (15%) Query: 297 VEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 350 +++ L C +C E KN ++ LPC H F RCLQN + T SCP CR++S+ P Sbjct: 16 IDKQFLICSICLERY--KNPKV--LPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILP 70 >gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] Length = 771 Score = 40.0 bits (92), Expect = 0.003 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 9/59 (15%) Query: 297 VEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 350 +++ L C +C E KN ++ LPC H F RCLQN + T SCP CR++S+ P Sbjct: 43 IDKQFLICSICLERY--KNPKV--LPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILP 97 >gi|34452686 ring finger protein, LIM domain interacting [Homo sapiens] Length = 624 Score = 38.9 bits (89), Expect = 0.007 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 3/50 (6%) Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMKPG 351 C +C E N +L+ LPCSH +H+ C+ + +CP CRR+ + G Sbjct: 570 CSVCITEYTEGN-KLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASG 618 >gi|34452684 ring finger protein, LIM domain interacting [Homo sapiens] Length = 624 Score = 38.9 bits (89), Expect = 0.007 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 3/50 (6%) Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMKPG 351 C +C E N +L+ LPCSH +H+ C+ + +CP CRR+ + G Sbjct: 570 CSVCITEYTEGN-KLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASG 618 >gi|150170725 zinc and ring finger 4 [Homo sapiens] Length = 429 Score = 38.5 bits (88), Expect = 0.009 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 5/47 (10%) Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCL----QNNGTRSCPNCRRS 346 C +C + E+ +L+ LPCSH +H +C+ RSCP C++S Sbjct: 309 CAICLDEY-EEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQS 354 >gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) [Homo sapiens] Length = 543 Score = 38.1 bits (87), Expect = 0.012 Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 15/105 (14%) Query: 130 GNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKA 189 GN L + AL+ + +A++ +N + + + YA+ DY+KA CK Sbjct: 11 GNKALSVGNIDDALQCYSEAIKLDPHNHV------LYSNRSAAYAKKGDYQKAYEDGCKT 64 Query: 190 AELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMK 234 +L ++GKG+S K A A L R A EE +K Sbjct: 65 VDLKPDWGKGYSRK---------AAALEFLNRFEEAKRTYEEGLK 100 >gi|58331195 ring finger and CHY zinc finger domain containing 1 isoform 1 [Homo sapiens] Length = 261 Score = 37.4 bits (85), Expect = 0.020 Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 13/83 (15%) Query: 270 HCLSESIYRSKGLQRELRAHVVRFHECVEETELY-CGLCGESIGEKNSRLQALPCSHIFH 328 HCL ++ + LQ H+C+E C +C E I LPC H+ H Sbjct: 118 HCLKCNLCLAMNLQGR--------HKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLH 169 Query: 329 LRCLQ---NNGTRSCPNCRRSSM 348 C + G R CP C S++ Sbjct: 170 RTCYEEMLKEGYR-CPLCMHSAL 191 >gi|21071001 autocrine motility factor receptor [Homo sapiens] Length = 643 Score = 37.4 bits (85), Expect = 0.020 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 13/107 (12%) Query: 249 LLCFADIHRSRGDLEL-SQLK--LHCLSESIYRSKGLQRELRAHVVRFHECVEETELY-- 303 +L F +I S L + QL+ H + I R K R + RF E Sbjct: 279 MLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARFAVATPEELAVNN 338 Query: 304 --CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRS 346 C +C +S+ + LPC H+FH CL++ SCP CR S Sbjct: 339 DDCAICWDSM----QAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMS 381 >gi|4503729 FK506 binding protein 52 [Homo sapiens] Length = 459 Score = 37.0 bits (84), Expect = 0.027 Identities = 39/153 (25%), Positives = 62/153 (40%), Gaps = 18/153 (11%) Query: 23 EKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLK-----FAVVQIDTARELE 77 EKA + W E+ + + G T + + G+YK+ L + ++ +++ E Sbjct: 253 EKAKESWEMNSEEKLEQSTIVKERG---TVYFKEGKYKQALLQYKKIVSWLEYESSFSNE 309 Query: 78 DAD----FLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAF 133 +A L S+LNLA + KL F I C L L G A Sbjct: 310 EAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLF------RRGEAH 363 Query: 134 LGLSVFQKALESFEKALRYAHNNDDAMLECRVC 166 L ++ F+ A F+K L+ NN A + VC Sbjct: 364 LAVNDFELARADFQKVLQLYPNNKAAKTQLAVC 396 >gi|5031825 ring finger protein 103 [Homo sapiens] Length = 685 Score = 36.6 bits (83), Expect = 0.035 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 4/49 (8%) Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCL---QNNGTRSCPNCRRSSMK 349 C +C E+ E L LPC H+FH C+ G CP CR S K Sbjct: 621 CVVCLENF-ENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYK 668 >gi|37595553 ring finger protein 111 [Homo sapiens] Length = 986 Score = 36.6 bits (83), Expect = 0.035 Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 3/49 (6%) Query: 298 EETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCR 344 E+TE C +C SI E+ ++ LPC H+FH C+ + CP CR Sbjct: 928 EDTEEKCTIC-LSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICR 975 >gi|188497705 BRCA1 associated protein [Homo sapiens] Length = 592 Score = 36.2 bits (82), Expect = 0.046 Identities = 15/41 (36%), Positives = 22/41 (53%) Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCR 344 C +C E + E + + C+H FH +CLQ +CP CR Sbjct: 264 CTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCR 304 >gi|32454739 tripartite motif-containing 3 [Homo sapiens] Length = 744 Score = 36.2 bits (82), Expect = 0.046 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 5/37 (13%) Query: 319 QALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 350 + LPC H F RCLQN + T SCP CR++S+ P Sbjct: 33 KVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILP 69 >gi|32454737 tripartite motif-containing 3 [Homo sapiens] Length = 744 Score = 36.2 bits (82), Expect = 0.046 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 5/37 (13%) Query: 319 QALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 350 + LPC H F RCLQN + T SCP CR++S+ P Sbjct: 33 KVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILP 69 >gi|7706039 ring finger protein 181 [Homo sapiens] Length = 153 Score = 36.2 bits (82), Expect = 0.046 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%) Query: 299 ETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCR 344 + EL C +C E+ + ++ +PC H+FH C+ + T SCP CR Sbjct: 71 QAELKCPVCLLEFEEEETAIE-MPCHHLFHSSCILPWLSKTNSCPLCR 117 >gi|27436927 synoviolin 1 isoform b [Homo sapiens] Length = 617 Score = 35.8 bits (81), Expect = 0.060 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 5/48 (10%) Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMK 349 C +C E E + + LPC+HIFH CL++ ++CP CR ++ Sbjct: 291 CIICRE---EMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLR 335 >gi|27436925 synoviolin 1 isoform a [Homo sapiens] Length = 616 Score = 35.8 bits (81), Expect = 0.060 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 5/48 (10%) Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMK 349 C +C E E + + LPC+HIFH CL++ ++CP CR ++ Sbjct: 291 CIICRE---EMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLR 335 >gi|7661950 SH2 domain binding protein 1 [Homo sapiens] Length = 1173 Score = 35.8 bits (81), Expect = 0.060 Identities = 40/186 (21%), Positives = 70/186 (37%), Gaps = 36/186 (19%) Query: 3 QDQTKQQIEKGLQLYQSNQTEKALQVWTKVLE--KSSDLMGRFRVLGCLV---------- 50 +DQ K+ I KG + Q ++ W ++ + + +D+ G G Sbjct: 389 EDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRILQEKVQAD 448 Query: 51 ----------TAHSEMGRYKEMLKFAVVQIDTARELEDAD------FLLESYLNLARSNE 94 H +G E K+ + +D A+ + D + + NLAR E Sbjct: 449 VPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYE 508 Query: 95 KLCEFHKTISYCKTCLGLPGTRAGAQLG-GQVSLSMGNAFLGLSVFQKALESFEKALRYA 153 +CEFH+ K L L G ++ GN F +A + F++AL+ Sbjct: 509 AMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGN-------FYEASDWFKEALQIN 561 Query: 154 HNNDDA 159 ++ DA Sbjct: 562 QDHPDA 567 >gi|239749332 PREDICTED: hypothetical protein XP_002347002 [Homo sapiens] Length = 183 Score = 35.4 bits (80), Expect = 0.078 Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 24/107 (22%) Query: 243 PLQALCLLCFADIHRSRGDLELSQLKLHCLSESIY---RSKGLQRELRAHVVRFHECVEE 299 P Q L + + + R LS L+ CL E +Y R K + E+ V+ E V Sbjct: 42 PGQPLLAILLTEEEQVRTAQRLSLLQ--CLPEEVYDPGRDKS-EEEMPECVICLLEFV-- 96 Query: 300 TELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRS--CPNCR 344 CG+ I + LPC H FHL C+ RS CP CR Sbjct: 97 -------CGDPI-------RCLPCKHFFHLDCIDTWLLRSFTCPYCR 129 >gi|239743424 PREDICTED: hypothetical protein XP_002342853 [Homo sapiens] Length = 183 Score = 35.4 bits (80), Expect = 0.078 Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 24/107 (22%) Query: 243 PLQALCLLCFADIHRSRGDLELSQLKLHCLSESIY---RSKGLQRELRAHVVRFHECVEE 299 P Q L + + + R LS L+ CL E +Y R K + E+ V+ E V Sbjct: 42 PGQPLLAILLTEEEQVRTAQRLSLLQ--CLPEEVYDPGRDKS-EEEMPECVICLLEFV-- 96 Query: 300 TELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRS--CPNCR 344 CG+ I + LPC H FHL C+ RS CP CR Sbjct: 97 -------CGDPI-------RCLPCKHFFHLDCIDTWLLRSFTCPYCR 129 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.135 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,731,083 Number of Sequences: 37866 Number of extensions: 520770 Number of successful extensions: 1797 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 21 Number of HSP's successfully gapped in prelim test: 100 Number of HSP's that attempted gapping in prelim test: 1693 Number of HSP's gapped (non-prelim): 175 length of query: 353 length of database: 18,247,518 effective HSP length: 103 effective length of query: 250 effective length of database: 14,347,320 effective search space: 3586830000 effective search space used: 3586830000 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.