Guide to the Human Genome
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Search of human proteins with 38045928

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38045928 43 kD receptor-associated protein of the synapse
isoform 2 [Homo sapiens]
         (353 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38045928 43 kD receptor-associated protein of the synapse iso...   722   0.0  
gi|15619013 43 kD receptor-associated protein of the synapse iso...   654   0.0  
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]         77   2e-14
gi|224548927 G-protein signaling modulator 1 (AGS3-like, C. eleg...    59   7e-09
gi|224548925 G-protein signaling modulator 1 (AGS3-like, C. eleg...    59   7e-09
gi|164519122 LGN protein [Homo sapiens]                                57   3e-08
gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens]       42   0.001
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]          40   0.002
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]          40   0.002
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]            40   0.002
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]    40   0.003
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]    40   0.003
gi|34452686 ring finger protein, LIM domain interacting [Homo sa...    39   0.007
gi|34452684 ring finger protein, LIM domain interacting [Homo sa...    39   0.007
gi|150170725 zinc and ring finger 4 [Homo sapiens]                     39   0.009
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi...    38   0.012
gi|58331195 ring finger and CHY zinc finger domain containing 1 ...    37   0.020
gi|21071001 autocrine motility factor receptor [Homo sapiens]          37   0.020
gi|4503729 FK506 binding protein 52 [Homo sapiens]                     37   0.027
gi|5031825 ring finger protein 103 [Homo sapiens]                      37   0.035
gi|37595553 ring finger protein 111 [Homo sapiens]                     37   0.035
gi|188497705 BRCA1 associated protein [Homo sapiens]                   36   0.046
gi|32454739 tripartite motif-containing 3 [Homo sapiens]               36   0.046
gi|32454737 tripartite motif-containing 3 [Homo sapiens]               36   0.046
gi|7706039 ring finger protein 181 [Homo sapiens]                      36   0.046
gi|27436927 synoviolin 1 isoform b [Homo sapiens]                      36   0.060
gi|27436925 synoviolin 1 isoform a [Homo sapiens]                      36   0.060
gi|7661950 SH2 domain binding protein 1 [Homo sapiens]                 36   0.060
gi|239749332 PREDICTED: hypothetical protein XP_002347002 [Homo ...    35   0.078
gi|239743424 PREDICTED: hypothetical protein XP_002342853 [Homo ...    35   0.078

>gi|38045928 43 kD receptor-associated protein of the synapse
           isoform 2 [Homo sapiens]
          Length = 353

 Score =  722 bits (1864), Expect = 0.0
 Identities = 353/353 (100%), Positives = 353/353 (100%)

Query: 1   MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60
           MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK
Sbjct: 1   MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60

Query: 61  EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120
           EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ
Sbjct: 61  EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120

Query: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180
           LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE
Sbjct: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180

Query: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240
           KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG
Sbjct: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240

Query: 241 DRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEET 300
           DRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEET
Sbjct: 241 DRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEET 300

Query: 301 ELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 353
           ELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV
Sbjct: 301 ELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 353


>gi|15619013 43 kD receptor-associated protein of the synapse
           isoform 1 [Homo sapiens]
          Length = 412

 Score =  654 bits (1686), Expect = 0.0
 Identities = 335/412 (81%), Positives = 343/412 (83%), Gaps = 59/412 (14%)

Query: 1   MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60
           MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK
Sbjct: 1   MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60

Query: 61  EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120
           EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ
Sbjct: 61  EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120

Query: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180
           LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE
Sbjct: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180

Query: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240
           KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG
Sbjct: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240

Query: 241 DRPLQALCLLCFADIHRSRGDLE---------------------------------LSQL 267
           DRPLQALCLLCFADIHRSRGDLE                                 +++ 
Sbjct: 241 DRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARK 300

Query: 268 KLHCLSESIYRSKGLQREL--------------------------RAHVVRFHECVEETE 301
            L    ++I R++ L  E+                          RAHVVRFHECVEETE
Sbjct: 301 ALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETE 360

Query: 302 LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 353
           LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV
Sbjct: 361 LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 412


>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
          Length = 2481

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 58/239 (24%), Positives = 110/239 (46%), Gaps = 13/239 (5%)

Query: 38  DLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLC 97
           D+ G  +V   L  AH  +G Y+E +K+    +  A++L D     ++Y NL  + + L 
Sbjct: 629 DMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALL 688

Query: 98  EFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNND 157
            F K     K  L L  +   +Q   +   ++G+ F+       A++ +E+ L  AH   
Sbjct: 689 NFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVK 748

Query: 158 DAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYR 217
           D  LE     +LG+ Y  ++ Y+KAL +  +  E+   Y +   L     +  H+A  Y 
Sbjct: 749 DRRLEASAYAALGTAYRMIQKYDKALGYHTQELEV---YQELSDLPGECRAHGHLAAVYM 805

Query: 218 LLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESI 276
            LG+   A +C EE + +  +  D  L+A          +  G++ ++++ ++ + E+I
Sbjct: 806 ALGKYTMAFKCYEEQLDLGQKLKDPSLEA----------QVYGNMGITKMNMNVMEEAI 854



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 56/263 (21%), Positives = 115/263 (43%), Gaps = 13/263 (4%)

Query: 23   EKALQVWTKVLE---KSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDA 79
            +KAL   T+ LE   + SDL G  R  G L   +  +G+Y    K    Q+D  ++L+D 
Sbjct: 771  DKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDP 830

Query: 80   DFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQL---GGQVSLSMGNAFLGL 136
                + Y N+  +   +    + I Y +  L +    +G +     G+   ++G+ +  L
Sbjct: 831  SLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEAL 890

Query: 137  SVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNY 196
              +++A++ +E+ L  A + +    + +    LG+ +  +   ++AL    K   + +  
Sbjct: 891  GDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHEL 950

Query: 197  GKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIH 256
            G+ ++   +A +   +   +  LG    A+ C E  + IA    DR L++        ++
Sbjct: 951  GEAFN---KAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVY 1007

Query: 257  RSRGD----LELSQLKLHCLSES 275
            +  G+    L+  QL L    E+
Sbjct: 1008 QQMGEYDTALQYHQLDLQIAEET 1030



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 62/269 (23%), Positives = 119/269 (44%), Gaps = 13/269 (4%)

Query: 22  TEKA---LQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELED 78
           TEK+   +Q    V +   D  G  R  G L +A    G Y+E L     Q+  A +L+D
Sbjct: 250 TEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKD 309

Query: 79  ADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSV 138
            +    +  +L      + ++   ++  K C+ L           +   +MG  ++ +  
Sbjct: 310 REAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGD 369

Query: 139 FQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGK 198
           F+ A++  E+ L+ A +  +   E R   +LGS Y   ++++KA+ +     EL     +
Sbjct: 370 FENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELME 429

Query: 199 GWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRS 258
             +++ RA +   +  A R +  L  A +  E+ + IA    DR  +         IH+ 
Sbjct: 430 K-AIEMRAYA--GLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQM 486

Query: 259 RGDLELSQLKLH----CLSESI--YRSKG 281
           +GD + + LKLH    C+++ +  Y ++G
Sbjct: 487 KGDYD-TALKLHKTHLCIAQELSDYAAQG 514



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 51/217 (23%), Positives = 91/217 (41%), Gaps = 11/217 (5%)

Query: 34  EKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSN 93
           ++S D +   R LG +   +  MG ++  ++     +  A++L +      +Y NL  + 
Sbjct: 345 KQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAY 404

Query: 94  EKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYA 153
                F K +SY    L L        +  +    +G+A   +   ++A +  E+ L  A
Sbjct: 405 HYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIA 464

Query: 154 HNNDDAMLECRVCCSLGSFYAQVKDYEKALFFP----CKAAELVNNYGKGWSLKYRAMSQ 209
            +  D   E R   +LG  +    DY+ AL       C A EL +   +G     RA   
Sbjct: 465 EDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQELSDYAAQG-----RAYG- 518

Query: 210 YHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQA 246
            +M  AY  LG    A++   + ++I+++  DR  QA
Sbjct: 519 -NMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQA 554



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 40/205 (19%), Positives = 93/205 (45%), Gaps = 3/205 (1%)

Query: 32  VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91
           + ++ SD   + R  G +  A++ +G Y + +K+   ++  + E+ D      ++ NLA 
Sbjct: 503 IAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAV 562

Query: 92  SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151
           + + L    + + + +  L +       Q   +   ++GN       + +A   +E+ LR
Sbjct: 563 AYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLR 622

Query: 152 YAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYH 211
            A +  D   E +VC +LG  +  + +Y++A+ +  +   L  +     S   +A +  +
Sbjct: 623 LAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLS---QAKAYCN 679

Query: 212 MAVAYRLLGRLGSAMECCEESMKIA 236
           + +A++ L     A EC +  + +A
Sbjct: 680 LGLAFKALLNFSKAEECQKYLLSLA 704



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 41/199 (20%), Positives = 86/199 (43%), Gaps = 3/199 (1%)

Query: 3    QDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRF---RVLGCLVTAHSEMGRY 59
            QDQ K     G         ++AL  + K L  + +L   F   +  G L + HS++G Y
Sbjct: 914  QDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNY 973

Query: 60   KEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGA 119
            ++ +     Q++ AR+++D     ++   L    +++ E+   + Y +  L +       
Sbjct: 974  EQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQIAEETNNP 1033

Query: 120  QLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDY 179
               G+   ++G  +  L  F++A+   E+ L  A   +D   +     SLG  +  +++Y
Sbjct: 1034 TCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNY 1093

Query: 180  EKALFFPCKAAELVNNYGK 198
             +A+ +  +   L    G+
Sbjct: 1094 SQAVMYLQEGLRLAEQLGR 1112



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 41/214 (19%), Positives = 85/214 (39%), Gaps = 6/214 (2%)

Query: 33   LEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARS 92
            L +  D    +R LG     H  MG  ++ L     ++  A EL +A    ++Y  L   
Sbjct: 910  LNRMQDQAKAYRGLG---NGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSL 966

Query: 93   NEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRY 152
            + +L  + + IS  +  L +        L    +  +G  +  +  +  AL+  +  L+ 
Sbjct: 967  HSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQI 1026

Query: 153  AHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHM 212
            A   ++   + R   +LG  Y  +  +E+A+ +  +   +         L  + +S   +
Sbjct: 1027 AEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMN---DLAAKTVSYSSL 1083

Query: 213  AVAYRLLGRLGSAMECCEESMKIALQHGDRPLQA 246
               +  L     A+   +E +++A Q G R  +A
Sbjct: 1084 GRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEA 1117



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 34/187 (18%), Positives = 78/187 (41%), Gaps = 9/187 (4%)

Query: 3   QDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGR------FRVLGCLVTAHSEM 56
           +++ +     G   +     +KA+     VLE + +LM +      +  LG       ++
Sbjct: 391 REEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDL 450

Query: 57  GRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTR 116
            R K+   +   Q+  A +L+D      +  NL   ++   ++   +   KT L +    
Sbjct: 451 ERAKQ---YHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLCIAQEL 507

Query: 117 AGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQV 176
           +     G+   +MGNA+  L ++ +A++   + L+ +   +D   +     +L   Y  +
Sbjct: 508 SDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQAL 567

Query: 177 KDYEKAL 183
             +++AL
Sbjct: 568 GAHDRAL 574



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 34/164 (20%), Positives = 60/164 (36%), Gaps = 37/164 (22%)

Query: 120 QLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDY 179
           +L G V  ++ +A+  L   +K+    ++ L  A    D   ECR   +LGS +    +Y
Sbjct: 231 KLRGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNY 290

Query: 180 EKA---------LFFPCKAAELVNNYGKGWSLKYRAMSQY-------------------- 210
            +A         L    K  E  ++        Y A+  Y                    
Sbjct: 291 REALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDE 350

Query: 211 --------HMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQA 246
                   +M   Y  +G   +A++C E+ +KIA   G++  +A
Sbjct: 351 LSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEA 394


>gi|224548927 G-protein signaling modulator 1 (AGS3-like, C.
           elegans) isoform a [Homo sapiens]
          Length = 675

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 17/180 (9%)

Query: 70  IDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSM 129
           +   +EL D      +Y NL  ++  L  F +  ++ K  L +           +   ++
Sbjct: 196 LSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNL 255

Query: 130 GNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCK- 188
           GNA + L  F  A E ++K L+ +    D  +E + C SLG+ Y  ++DYE+A  +  + 
Sbjct: 256 GNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRH 315

Query: 189 ---AAELVNNYGKG---WSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDR 242
              A EL +  G+G   WSL            AY  +GR   A+   ++ ++I+ + GDR
Sbjct: 316 LLIAQELADRVGEGRACWSL----------GNAYVSMGRPAQALTFAKKHLQISQEIGDR 365



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 3/193 (1%)

Query: 32  VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91
           ++++  D   + R  G L   H  +G + E   F   ++  A+E  D      +Y NL  
Sbjct: 198 LVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGN 257

Query: 92  SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151
           ++  L  F     Y K  L L        +  Q   S+GN +  L  +++A E   + L 
Sbjct: 258 AHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLL 317

Query: 152 YAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYH 211
            A    D + E R C SLG+ Y  +    +AL F  K  ++    G          ++ +
Sbjct: 318 IAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHG---ELTARMN 374

Query: 212 MAVAYRLLGRLGS 224
           +A    +LGRL S
Sbjct: 375 VAQLQLVLGRLTS 387



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 5/122 (4%)

Query: 139 FQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGK 198
           F+  +  FE A++     +D      +   LG+ Y  +K++ +AL +      L    G 
Sbjct: 44  FKTGVAFFEAAVQVG--TEDLKTLSAIYSQLGNAYFYLKEHGRALEYHKHDLLLARTIGD 101

Query: 199 GWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRS 258
                  A +  ++    ++LGR   A  CC+  + IA + GD+  +A  L    +++ +
Sbjct: 102 RMG---EAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQGDKVGEARALYNIGNVYHA 158

Query: 259 RG 260
           +G
Sbjct: 159 KG 160


>gi|224548925 G-protein signaling modulator 1 (AGS3-like, C.
           elegans) isoform b [Homo sapiens]
          Length = 457

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 17/180 (9%)

Query: 70  IDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSM 129
           +   +EL D      +Y NL  ++  L  F +  ++ K  L +           +   ++
Sbjct: 196 LSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNL 255

Query: 130 GNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCK- 188
           GNA + L  F  A E ++K L+ +    D  +E + C SLG+ Y  ++DYE+A  +  + 
Sbjct: 256 GNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRH 315

Query: 189 ---AAELVNNYGKG---WSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDR 242
              A EL +  G+G   WSL            AY  +GR   A+   ++ ++I+ + GDR
Sbjct: 316 LLIAQELADRVGEGRACWSL----------GNAYVSMGRPAQALTFAKKHLQISQEIGDR 365



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 3/193 (1%)

Query: 32  VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91
           ++++  D   + R  G L   H  +G + E   F   ++  A+E  D      +Y NL  
Sbjct: 198 LVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGN 257

Query: 92  SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151
           ++  L  F     Y K  L L        +  Q   S+GN +  L  +++A E   + L 
Sbjct: 258 AHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLL 317

Query: 152 YAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYH 211
            A    D + E R C SLG+ Y  +    +AL F  K  ++    G          ++ +
Sbjct: 318 IAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHG---ELTARMN 374

Query: 212 MAVAYRLLGRLGS 224
           +A    +LGRL S
Sbjct: 375 VAQLQLVLGRLTS 387



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 5/122 (4%)

Query: 139 FQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGK 198
           F+  +  FE A++     +D      +   LG+ Y  +K++ +AL +      L    G 
Sbjct: 44  FKTGVAFFEAAVQVG--TEDLKTLSAIYSQLGNAYFYLKEHGRALEYHKHDLLLARTIGD 101

Query: 199 GWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRS 258
                  A +  ++    ++LGR   A  CC+  + IA + GD+  +A  L    +++ +
Sbjct: 102 RMG---EAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQGDKVGEARALYNIGNVYHA 158

Query: 259 RG 260
           +G
Sbjct: 159 KG 160


>gi|164519122 LGN protein [Homo sapiens]
          Length = 684

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 9/194 (4%)

Query: 4   DQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEML 63
           ++ +  ++  +  Y+ N +         ++    D   + R  G L   H  +G +++ +
Sbjct: 172 EEVRDALQAAVDFYEENLS---------LVTALGDRAAQGRAFGNLGNTHYLLGNFRDAV 222

Query: 64  KFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGG 123
                ++  A+E  D      +Y NL  +   L EF     Y K  L L        +  
Sbjct: 223 IAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEA 282

Query: 124 QVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKAL 183
           Q   S+GN +  L  ++KA++   K L  A   +D + E R C SLG+ Y  + ++++A+
Sbjct: 283 QSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAM 342

Query: 184 FFPCKAAELVNNYG 197
            F  K  E+    G
Sbjct: 343 HFAEKHLEISREVG 356



 Score = 37.0 bits (84), Expect = 0.027
 Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 12/140 (8%)

Query: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180
           L G+     G+   G+S F+ A++            +D      +   LG+ Y  + DY 
Sbjct: 29  LEGERLCKSGDCRAGVSFFEAAVQV---------GTEDLKTLSAIYSQLGNAYFYLHDYA 79

Query: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240
           KAL +      L    G        A +  ++    ++LG    A+ CC+  + I+ +  
Sbjct: 80  KALEYHHHDLTLARTIGDQLG---EAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELN 136

Query: 241 DRPLQALCLLCFADIHRSRG 260
           D+  +A  L    +++ ++G
Sbjct: 137 DKVGEARALYNLGNVYHAKG 156



 Score = 35.8 bits (81), Expect = 0.060
 Identities = 55/254 (21%), Positives = 95/254 (37%), Gaps = 40/254 (15%)

Query: 66  AVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLG-GQ 124
           A VQ+ T    ED   L   Y  L  +   L ++ K + Y    L L  T  G QLG  +
Sbjct: 49  AAVQVGT----EDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLART-IGDQLGEAK 103

Query: 125 VSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALF 184
            S ++GN    L  F +A+   ++ L  +   +D + E R   +LG+ Y     + K   
Sbjct: 104 ASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVY-----HAKGKS 158

Query: 185 FPCKAAELVNNYGKGWSLKYRAMSQYH----------------------MAVAYRLLGRL 222
           F C   + V  + +      +A   ++                      +   + LLG  
Sbjct: 159 FGCPGPQDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNF 218

Query: 223 GSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLELSQLKLHCLSESIYRSKGL 282
             A+   E+ + IA + GD+  +        + +   G+ E +       SE   ++  L
Sbjct: 219 RDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETA-------SEYYKKTLLL 271

Query: 283 QRELRAHVVRFHEC 296
            R+L+   V    C
Sbjct: 272 ARQLKDRAVEAQSC 285



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 27/127 (21%), Positives = 51/127 (40%)

Query: 32  VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91
           + ++  D     R    L  A+  +G ++   ++    +  AR+L+D     +S  +L  
Sbjct: 231 IAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGN 290

Query: 92  SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151
           +   L ++ K I Y    L +          G+   S+GNA+  L    +A+   EK L 
Sbjct: 291 TYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLE 350

Query: 152 YAHNNDD 158
            +    D
Sbjct: 351 ISREVGD 357



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 23  EKALQVWTK---VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDA 79
           EKA+    K   + ++ +D +G  R    L  A++ +G + + + FA   ++ +RE+ D 
Sbjct: 299 EKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDK 358

Query: 80  DFLLESYLNLA 90
              L + LNL+
Sbjct: 359 SGELTARLNLS 369


>gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens]
          Length = 1208

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 8/57 (14%)

Query: 298  EETELYCGLCGESIGEKNSRLQALPCSHIFHLRC----LQNNGTRSCPNCRRSSMKP 350
            EE E  C +C E++  +N  L  LPC+H FH +C    L   GT  CP CR   + P
Sbjct: 1142 EEEEEPCVICHENLSPEN--LSVLPCAHKFHAQCIRPWLMQQGT--CPTCRLHVLLP 1194


>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 8/87 (9%)

Query: 81  FLLESYLNLARSNEKLCEFHKTISYCKTCLGL-PGTRAGAQLGGQVSLSMGNAFLGLSVF 139
           FLL ++LNLA    KL E+ K +  C   LGL      G    G+  L M         F
Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE-------F 367

Query: 140 QKALESFEKALRYAHNNDDAMLECRVC 166
           + A   FEK L     N  A L+  +C
Sbjct: 368 ESAKGDFEKVLEVNPQNKAARLQISMC 394


>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 8/87 (9%)

Query: 81  FLLESYLNLARSNEKLCEFHKTISYCKTCLGL-PGTRAGAQLGGQVSLSMGNAFLGLSVF 139
           FLL ++LNLA    KL E+ K +  C   LGL      G    G+  L M         F
Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE-------F 367

Query: 140 QKALESFEKALRYAHNNDDAMLECRVC 166
           + A   FEK L     N  A L+  +C
Sbjct: 368 ESAKGDFEKVLEVNPQNKAARLQISMC 394


>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 8/87 (9%)

Query: 81  FLLESYLNLARSNEKLCEFHKTISYCKTCLGL-PGTRAGAQLGGQVSLSMGNAFLGLSVF 139
           FLL ++LNLA    KL E+ K +  C   LGL      G    G+  L M         F
Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE-------F 367

Query: 140 QKALESFEKALRYAHNNDDAMLECRVC 166
           + A   FEK L     N  A L+  +C
Sbjct: 368 ESAKGDFEKVLEVNPQNKAARLQISMC 394


>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
          Length = 744

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 9/59 (15%)

Query: 297 VEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 350
           +++  L C +C E    KN ++  LPC H F  RCLQN     + T SCP CR++S+ P
Sbjct: 16  IDKQFLICSICLERY--KNPKV--LPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILP 70


>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
          Length = 771

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 9/59 (15%)

Query: 297 VEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 350
           +++  L C +C E    KN ++  LPC H F  RCLQN     + T SCP CR++S+ P
Sbjct: 43  IDKQFLICSICLERY--KNPKV--LPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILP 97


>gi|34452686 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 3/50 (6%)

Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMKPG 351
           C +C     E N +L+ LPCSH +H+ C+    +   +CP CRR+ +  G
Sbjct: 570 CSVCITEYTEGN-KLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASG 618


>gi|34452684 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 3/50 (6%)

Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMKPG 351
           C +C     E N +L+ LPCSH +H+ C+    +   +CP CRR+ +  G
Sbjct: 570 CSVCITEYTEGN-KLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASG 618


>gi|150170725 zinc and ring finger 4 [Homo sapiens]
          Length = 429

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 5/47 (10%)

Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCL----QNNGTRSCPNCRRS 346
           C +C +   E+  +L+ LPCSH +H +C+         RSCP C++S
Sbjct: 309 CAICLDEY-EEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQS 354


>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
           protein) [Homo sapiens]
          Length = 543

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 15/105 (14%)

Query: 130 GNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKA 189
           GN  L +     AL+ + +A++   +N        +  +  + YA+  DY+KA    CK 
Sbjct: 11  GNKALSVGNIDDALQCYSEAIKLDPHNHV------LYSNRSAAYAKKGDYQKAYEDGCKT 64

Query: 190 AELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMK 234
            +L  ++GKG+S K         A A   L R   A    EE +K
Sbjct: 65  VDLKPDWGKGYSRK---------AAALEFLNRFEEAKRTYEEGLK 100


>gi|58331195 ring finger and CHY zinc finger domain containing 1
           isoform 1 [Homo sapiens]
          Length = 261

 Score = 37.4 bits (85), Expect = 0.020
 Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 13/83 (15%)

Query: 270 HCLSESIYRSKGLQRELRAHVVRFHECVEETELY-CGLCGESIGEKNSRLQALPCSHIFH 328
           HCL  ++  +  LQ          H+C+E      C +C E I         LPC H+ H
Sbjct: 118 HCLKCNLCLAMNLQGR--------HKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLH 169

Query: 329 LRCLQ---NNGTRSCPNCRRSSM 348
             C +     G R CP C  S++
Sbjct: 170 RTCYEEMLKEGYR-CPLCMHSAL 191


>gi|21071001 autocrine motility factor receptor [Homo sapiens]
          Length = 643

 Score = 37.4 bits (85), Expect = 0.020
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 13/107 (12%)

Query: 249 LLCFADIHRSRGDLEL-SQLK--LHCLSESIYRSKGLQRELRAHVVRFHECVEETELY-- 303
           +L F +I  S   L +  QL+   H +   I R K   R +     RF     E      
Sbjct: 279 MLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARFAVATPEELAVNN 338

Query: 304 --CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRS 346
             C +C +S+       + LPC H+FH  CL++      SCP CR S
Sbjct: 339 DDCAICWDSM----QAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMS 381


>gi|4503729 FK506 binding protein 52 [Homo sapiens]
          Length = 459

 Score = 37.0 bits (84), Expect = 0.027
 Identities = 39/153 (25%), Positives = 62/153 (40%), Gaps = 18/153 (11%)

Query: 23  EKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLK-----FAVVQIDTARELE 77
           EKA + W    E+  +     +  G   T + + G+YK+ L       + ++ +++   E
Sbjct: 253 EKAKESWEMNSEEKLEQSTIVKERG---TVYFKEGKYKQALLQYKKIVSWLEYESSFSNE 309

Query: 78  DAD----FLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAF 133
           +A       L S+LNLA  + KL  F   I  C   L L                 G A 
Sbjct: 310 EAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLF------RRGEAH 363

Query: 134 LGLSVFQKALESFEKALRYAHNNDDAMLECRVC 166
           L ++ F+ A   F+K L+   NN  A  +  VC
Sbjct: 364 LAVNDFELARADFQKVLQLYPNNKAAKTQLAVC 396


>gi|5031825 ring finger protein 103 [Homo sapiens]
          Length = 685

 Score = 36.6 bits (83), Expect = 0.035
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 4/49 (8%)

Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCL---QNNGTRSCPNCRRSSMK 349
           C +C E+  E    L  LPC H+FH  C+      G   CP CR  S K
Sbjct: 621 CVVCLENF-ENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYK 668


>gi|37595553 ring finger protein 111 [Homo sapiens]
          Length = 986

 Score = 36.6 bits (83), Expect = 0.035
 Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 3/49 (6%)

Query: 298 EETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCR 344
           E+TE  C +C  SI E+   ++ LPC H+FH  C+       + CP CR
Sbjct: 928 EDTEEKCTIC-LSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICR 975


>gi|188497705 BRCA1 associated protein [Homo sapiens]
          Length = 592

 Score = 36.2 bits (82), Expect = 0.046
 Identities = 15/41 (36%), Positives = 22/41 (53%)

Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCR 344
           C +C E + E  + +    C+H FH +CLQ     +CP CR
Sbjct: 264 CTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCR 304


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 36.2 bits (82), Expect = 0.046
 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 5/37 (13%)

Query: 319 QALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 350
           + LPC H F  RCLQN     + T SCP CR++S+ P
Sbjct: 33  KVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILP 69


>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 36.2 bits (82), Expect = 0.046
 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 5/37 (13%)

Query: 319 QALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 350
           + LPC H F  RCLQN     + T SCP CR++S+ P
Sbjct: 33  KVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILP 69


>gi|7706039 ring finger protein 181 [Homo sapiens]
          Length = 153

 Score = 36.2 bits (82), Expect = 0.046
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)

Query: 299 ETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCR 344
           + EL C +C     E+ + ++ +PC H+FH  C+    + T SCP CR
Sbjct: 71  QAELKCPVCLLEFEEEETAIE-MPCHHLFHSSCILPWLSKTNSCPLCR 117


>gi|27436927 synoviolin 1 isoform b [Homo sapiens]
          Length = 617

 Score = 35.8 bits (81), Expect = 0.060
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 5/48 (10%)

Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMK 349
           C +C E   E  +  + LPC+HIFH  CL++     ++CP CR   ++
Sbjct: 291 CIICRE---EMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLR 335


>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
          Length = 616

 Score = 35.8 bits (81), Expect = 0.060
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 5/48 (10%)

Query: 304 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMK 349
           C +C E   E  +  + LPC+HIFH  CL++     ++CP CR   ++
Sbjct: 291 CIICRE---EMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLR 335


>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
          Length = 1173

 Score = 35.8 bits (81), Expect = 0.060
 Identities = 40/186 (21%), Positives = 70/186 (37%), Gaps = 36/186 (19%)

Query: 3   QDQTKQQIEKGLQLYQSNQTEKALQVWTKVLE--KSSDLMGRFRVLGCLV---------- 50
           +DQ K+ I KG     + Q    ++ W ++ +  + +D+ G     G             
Sbjct: 389 EDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRILQEKVQAD 448

Query: 51  ----------TAHSEMGRYKEMLKFAVVQIDTARELEDAD------FLLESYLNLARSNE 94
                       H  +G   E  K+ +  +D A+   + D        + +  NLAR  E
Sbjct: 449 VPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYE 508

Query: 95  KLCEFHKTISYCKTCLGLPGTRAGAQLG-GQVSLSMGNAFLGLSVFQKALESFEKALRYA 153
            +CEFH+     K  L          L  G ++   GN       F +A + F++AL+  
Sbjct: 509 AMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGN-------FYEASDWFKEALQIN 561

Query: 154 HNNDDA 159
            ++ DA
Sbjct: 562 QDHPDA 567


>gi|239749332 PREDICTED: hypothetical protein XP_002347002 [Homo
           sapiens]
          Length = 183

 Score = 35.4 bits (80), Expect = 0.078
 Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 24/107 (22%)

Query: 243 PLQALCLLCFADIHRSRGDLELSQLKLHCLSESIY---RSKGLQRELRAHVVRFHECVEE 299
           P Q L  +   +  + R    LS L+  CL E +Y   R K  + E+   V+   E V  
Sbjct: 42  PGQPLLAILLTEEEQVRTAQRLSLLQ--CLPEEVYDPGRDKS-EEEMPECVICLLEFV-- 96

Query: 300 TELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRS--CPNCR 344
                  CG+ I       + LPC H FHL C+     RS  CP CR
Sbjct: 97  -------CGDPI-------RCLPCKHFFHLDCIDTWLLRSFTCPYCR 129


>gi|239743424 PREDICTED: hypothetical protein XP_002342853 [Homo
           sapiens]
          Length = 183

 Score = 35.4 bits (80), Expect = 0.078
 Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 24/107 (22%)

Query: 243 PLQALCLLCFADIHRSRGDLELSQLKLHCLSESIY---RSKGLQRELRAHVVRFHECVEE 299
           P Q L  +   +  + R    LS L+  CL E +Y   R K  + E+   V+   E V  
Sbjct: 42  PGQPLLAILLTEEEQVRTAQRLSLLQ--CLPEEVYDPGRDKS-EEEMPECVICLLEFV-- 96

Query: 300 TELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRS--CPNCR 344
                  CG+ I       + LPC H FHL C+     RS  CP CR
Sbjct: 97  -------CGDPI-------RCLPCKHFFHLDCIDTWLLRSFTCPYCR 129


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,731,083
Number of Sequences: 37866
Number of extensions: 520770
Number of successful extensions: 1797
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 1693
Number of HSP's gapped (non-prelim): 175
length of query: 353
length of database: 18,247,518
effective HSP length: 103
effective length of query: 250
effective length of database: 14,347,320
effective search space: 3586830000
effective search space used: 3586830000
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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