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Search of human proteins with 37622896
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37622896 LON peptidase N-terminal domain and ring finger 3
isoform 2 [Homo sapiens]
(718 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37622896 LON peptidase N-terminal domain and ring finger 3 is... 1466 0.0
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 1446 0.0
gi|148528975 LON peptidase N-terminal domain and ring finger 2 [... 457 e-128
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 409 e-114
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 55 2e-07
gi|24025688 ligand of numb-protein X 2 [Homo sapiens] 54 4e-07
gi|31377566 ring finger protein 168 [Homo sapiens] 54 5e-07
gi|21071052 helicase-like transcription factor [Homo sapiens] 54 5e-07
gi|21071054 helicase-like transcription factor [Homo sapiens] 54 5e-07
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 54 7e-07
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 52 1e-06
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 52 1e-06
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 52 1e-06
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 52 1e-06
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 52 1e-06
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 52 2e-06
gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] 52 2e-06
gi|37595555 ring finger protein 125 [Homo sapiens] 51 3e-06
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 51 4e-06
gi|54792146 tripartite motif-containing 47 [Homo sapiens] 51 4e-06
gi|62865604 tripartite motif protein 31 [Homo sapiens] 50 7e-06
gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens] 50 7e-06
gi|37655169 ring finger protein 135 isoform 2 [Homo sapiens] 50 1e-05
gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens] 50 1e-05
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 50 1e-05
gi|38679905 tripartite motif-containing 65 [Homo sapiens] 50 1e-05
gi|7110679 tetratricopeptide repeat domain 33 [Homo sapiens] 50 1e-05
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 49 1e-05
gi|22749269 ring finger protein 129 [Homo sapiens] 49 1e-05
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 49 2e-05
>gi|37622896 LON peptidase N-terminal domain and ring finger 3
isoform 2 [Homo sapiens]
Length = 718
Score = 1466 bits (3795), Expect = 0.0
Identities = 718/718 (100%), Positives = 718/718 (100%)
Query: 1 MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP 60
MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP
Sbjct: 1 MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP 60
Query: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA
Sbjct: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
Query: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL
Sbjct: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
Query: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240
CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP
Sbjct: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240
Query: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA
Sbjct: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
Query: 301 EIACKLRPMGFKDNLELPHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKW 360
EIACKLRPMGFKDNLELPHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKW
Sbjct: 301 EIACKLRPMGFKDNLELPHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKW 360
Query: 361 DATSPKAASSKTGKCQEKKRKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFD 420
DATSPKAASSKTGKCQEKKRKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFD
Sbjct: 361 DATSPKAASSKTGKCQEKKRKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFD 420
Query: 421 ASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNV 480
ASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNV
Sbjct: 421 ASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNV 480
Query: 481 IMEELIAKFLPEELKERRKLYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRL 540
IMEELIAKFLPEELKERRKLYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRL
Sbjct: 481 IMEELIAKFLPEELKERRKLYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRL 540
Query: 541 MIRRCIETGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQS 600
MIRRCIETGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQS
Sbjct: 541 MIRRCIETGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQS 600
Query: 601 QRDGYNTADIEYIEDQKVQGEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMP 660
QRDGYNTADIEYIEDQKVQGEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMP
Sbjct: 601 QRDGYNTADIEYIEDQKVQGEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMP 660
Query: 661 EKDADPQMNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 718
EKDADPQMNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN
Sbjct: 661 EKDADPQMNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 718
>gi|73747840 LON peptidase N-terminal domain and ring finger 3
isoform 1 [Homo sapiens]
Length = 759
Score = 1446 bits (3743), Expect = 0.0
Identities = 718/759 (94%), Positives = 718/759 (94%), Gaps = 41/759 (5%)
Query: 1 MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP 60
MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP
Sbjct: 1 MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP 60
Query: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA
Sbjct: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
Query: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL
Sbjct: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
Query: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240
CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP
Sbjct: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240
Query: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA
Sbjct: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
Query: 301 EIACKLRPMGFK-----------------------------------------DNLELPH 319
EIACKLRPMGFK DNLELPH
Sbjct: 301 EIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPH 360
Query: 320 CSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK 379
CSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK
Sbjct: 361 CSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK 420
Query: 380 RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTT 439
RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTT
Sbjct: 421 RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTT 480
Query: 440 PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRK 499
PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRK
Sbjct: 481 PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRK 540
Query: 500 LYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGD 559
LYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGD
Sbjct: 541 LYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGD 600
Query: 560 PVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQ 619
PVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQ
Sbjct: 601 PVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQ 660
Query: 620 GEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWM 679
GEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWM
Sbjct: 661 GEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWM 720
Query: 680 LAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 718
LAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN
Sbjct: 721 LAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 759
>gi|148528975 LON peptidase N-terminal domain and ring finger 2
[Homo sapiens]
Length = 754
Score = 457 bits (1177), Expect = e-128
Identities = 289/711 (40%), Positives = 381/711 (53%), Gaps = 74/711 (10%)
Query: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
G + P+ + L DALA GR+ EAL +R + L E+LE+L L V
Sbjct: 52 GLAQPDRGLCLRLGDALARAGRLPEALGAFRGAARLGALRPEELEELAGGLVRAV----G 107
Query: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
L P + A E G A A D C +C L PV+L CG T CK
Sbjct: 108 LRDRPLSAENPGGEPEAPGEGGPAPEPRAPR--DLLGCPRCRRLLHKPVTLPCGLTVCKR 165
Query: 181 CLERGRAADRRCALCGVKLSALMVA-----------TGRARGARRAGQQPPPPLRVNVVL 229
C+E G A + V LS L+ G+AR +R Q LR + L
Sbjct: 166 CVEPGPARPQ-VRRVNVVLSGLLEKCFPAECRLRRLAGQARSLQRQQQPEAALLRCDQAL 224
Query: 230 SGLLGKLFPGPARASQLRHEGNRLYRE-RQVEAALLKYNEAVKLAPNDHLLYSN---RSQ 285
+L P LR E LY + E AL +A N+ LL ++Q
Sbjct: 225 -----ELAPDDNSLLLLRAE---LYLTMKNYEQAL---QDASAACQNEPLLIKGHQVKAQ 273
Query: 286 IYFTLESHENALHDAEIACKLRPM--GFKDNLELPHC--------------SSQEEAAAR 329
L + L + L P K + C +S ++ +
Sbjct: 274 ALSGLGRSKEVLKEFLYCLALNPECNSVKKEAQKVMCEVLFSATANVHENLTSSIQSRLK 333
Query: 330 GDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKKRKHCQIESQE 389
G S M+ + +G ++ E+ + T+ G E+ +K +ES
Sbjct: 334 AQGHSHMNAQALLEEGDAGSSENSSEKSDMLGNTNSSVLYFILGLHFEEDKK--ALESIL 391
Query: 390 ETGMPNKASKQDPPTDQGDKPALSLPLA----------------------SFDASDLECA 427
T P+ K+ P D D P L+ P S D +D ECA
Sbjct: 392 PTA-PSAGLKRQFPDDVEDAPDLNAPGKIPKKDLSLQRSPNSETEESQGLSLDVTDFECA 450
Query: 428 LCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIA 487
LCMRL +EPVTTPCGHTFCLKCLERCLDH CPLCKD LS+ LASR ++ V+ EELI
Sbjct: 451 LCMRLLFEPVTTPCGHTFCLKCLERCLDHAPHCPLCKDKLSELLASRNFNITVLAEELIF 510
Query: 488 KFLPEELKERRKLYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIE 547
++LP+EL +R+++Y+EEM ELSNL ++VPIFVC MA+PTVPCPLH+FEP YRLMIRRC+E
Sbjct: 511 RYLPDELSDRKRIYDEEMSELSNLTRDVPIFVCAMAFPTVPCPLHVFEPRYRLMIRRCME 570
Query: 548 TGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNT 607
TGT++FGMCL G +EYGC+LEI++V+ F DG SVVD+IG RFRVL RDGYNT
Sbjct: 571 TGTKRFGMCLSAEHAGLSEYGCMLEIKDVRTFPDGSSVVDAIGISRFRVLSHRHRDGYNT 630
Query: 608 ADIEYIEDQKVQGEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQ 667
ADIEY+ED+KV+G + EL LH+ V+QQ+ WF SL+ +K +IL+HFG MP+++ +PQ
Sbjct: 631 ADIEYLEDEKVEGPEYEELAALHDSVHQQSVSWFASLQDRMKEQILSHFGVMPDREPEPQ 690
Query: 668 MNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 718
NP+GPAW WW+LAVLPLE +AQL L M SLK+RL IRR+L I+R N
Sbjct: 691 SNPSGPAWSWWILAVLPLERKAQLAILGMTSLKERLLAIRRILVIITRKMN 741
>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
sapiens]
Length = 773
Score = 409 bits (1052), Expect = e-114
Identities = 187/306 (61%), Positives = 236/306 (77%), Gaps = 1/306 (0%)
Query: 414 LPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLAS 473
+P D SD EC+LCMRLF+EPVTTPCGH+FC CLERCLDH CPLCK+ L + LA
Sbjct: 467 IPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLAD 526
Query: 474 RKYSKNVIMEELIAKFLPEELKERRKLYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHI 533
R+Y ++EELI K+LP+EL ER+K+Y+EE ELS+L KNVPIFVCTMAYPTVPCPLH+
Sbjct: 527 RRYCVTQLLEELIVKYLPDELSERKKIYDEETAELSHLTKNVPIFVCTMAYPTVPCPLHV 586
Query: 534 FEPCYRLMIRRCIETGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRR 593
FEP YRLMIRR I+TGT+QFGMC+ D FA+YGC+L+IRNV F DGRSVVD++G +R
Sbjct: 587 FEPRYRLMIRRSIQTGTKQFGMCVSDTQNSFADYGCMLQIRNVHFLPDGRSVVDTVGGKR 646
Query: 594 FRVLHQSQRDGYNTADIEYIEDQKVQGED-CAELMGLHNCVYQQASLWFHSLKLSLKNRI 652
FRVL + +DGY TADIEY+ED KV+ ED L LH+ VY QA WF +L+ +++I
Sbjct: 647 FRVLKRGMKDGYCTADIEYLEDVKVENEDEIKNLRELHDLVYSQACSWFQNLRDRFRSQI 706
Query: 653 LNHFGPMPEKDADPQMNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAF 712
L HFG MPE++ + Q PNGPAWCWW+LAVLP++ R QL L+M+SLK+RL I+ +L +
Sbjct: 707 LQHFGSMPEREENLQAAPNGPAWCWWLLAVLPVDPRYQLSVLSMKSLKERLTKIQHILTY 766
Query: 713 ISRNQN 718
SR+Q+
Sbjct: 767 FSRDQS 772
Score = 84.0 bits (206), Expect = 5e-16
Identities = 71/241 (29%), Positives = 103/241 (42%), Gaps = 31/241 (12%)
Query: 68 KVLLTQADALASRGRIREALEVYRQLSERQQLVA-EQLEQLVRCLAEKVPQGEALAPAPP 126
++LL + + LA G ++ ALE + R E L LV CL L
Sbjct: 49 ELLLRRGELLALGGHLKGALEAFAAALRRGAPARPECLGALVDCLVFNYRLRHGL----- 103
Query: 127 DEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKLCLERGR 186
G AA GA A +C C GFLS+PV++ CGH++C+ CL R
Sbjct: 104 -------GWSAAPVAGADGGAGGL-----LRCLGCRGFLSEPVTVPCGHSYCRRCLRREL 151
Query: 187 AADRRCALCGVKLSALMVATGRARGARRAGQQPPP--------PLRVNVVLSGLLGKLFP 238
A RC LC +L AT A A +PPP R +VVL+ L K FP
Sbjct: 152 RA--RCRLCRDRLPP---ATASATDAEGTAPRPPPLAAAIAASDFRTSVVLNHLAEKWFP 206
Query: 239 GPARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALH 298
G ++ L + + AL EA++ P+D ++ R++ Y L+ + A+
Sbjct: 207 GQRERARAAGRLGELLHQGRYREALAAACEALRAEPSDLIVKIYRAESYAGLQEFKAAIE 266
Query: 299 D 299
D
Sbjct: 267 D 267
Score = 51.6 bits (122), Expect = 3e-06
Identities = 24/50 (48%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Query: 424 LECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLAS 473
L C C EPVT PCGH++C +CL R L A+C LC+D L AS
Sbjct: 121 LRCLGCRGFLSEPVTVPCGHSYCRRCLRREL--RARCRLCRDRLPPATAS 168
Score = 42.4 bits (98), Expect = 0.002
Identities = 18/40 (45%), Positives = 22/40 (55%)
Query: 156 FKCRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALC 195
F+C C +PV+ CGH+FCK CLER C LC
Sbjct: 477 FECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLC 516
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 55.5 bits (132), Expect = 2e-07
Identities = 26/74 (35%), Positives = 38/74 (51%)
Query: 421 ASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNV 480
A +L C++C+ F EPVTTPCGH FC CL LC + A + KN
Sbjct: 8 AEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNT 67
Query: 481 IMEELIAKFLPEEL 494
++ ++ +FL +L
Sbjct: 68 VLCNVVEQFLQADL 81
Score = 30.8 bits (68), Expect = 4.6
Identities = 14/38 (36%), Positives = 16/38 (42%)
Query: 158 CRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALC 195
C C +PV+ CGH FC CL A LC
Sbjct: 13 CSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLC 50
>gi|24025688 ligand of numb-protein X 2 [Homo sapiens]
Length = 690
Score = 54.3 bits (129), Expect = 4e-07
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 423 DLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIM 482
DL C +C++ +P+ TPCGHTFC KCL L CPL + L L + ++++
Sbjct: 47 DLVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKK---SSILV 103
Query: 483 EELIAKFL 490
+L+ K L
Sbjct: 104 HKLLDKLL 111
Score = 33.1 bits (74), Expect = 0.92
Identities = 15/32 (46%), Positives = 16/32 (50%)
Query: 151 EVWDGFKCRKCHGFLSDPVSLSCGHTFCKLCL 182
EV D C C L P+ CGHTFC CL
Sbjct: 43 EVDDDLVCHICLQPLLQPLDTPCGHTFCYKCL 74
>gi|31377566 ring finger protein 168 [Homo sapiens]
Length = 571
Score = 53.9 bits (128), Expect = 5e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 422 SDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDH-NAKCPLCKDGLSQCL---ASRKYS 477
S+ +C +CM + EPVT PC HT C C + ++ + CP C+ +S R
Sbjct: 12 SECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSL 71
Query: 478 KNVIMEELIAKFLPEELKERRKLYEEE 504
NV + +I K P E K R E E
Sbjct: 72 VNVELWTIIQKHYPRECKLRASGQESE 98
Score = 33.9 bits (76), Expect = 0.54
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLCLERG-RAADRRCALCGVKLSA 201
+C C L +PV+L C HT CK C + A C C ++S+
Sbjct: 15 QCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSS 60
>gi|21071052 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 53.9 bits (128), Expect = 5e-07
Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 18/122 (14%)
Query: 395 NKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCL 454
N S D P + K + L SD ECA+C+ PV T C H FC C+ + +
Sbjct: 729 NGPSGNDTPEELRKKLIRKMKLILSSGSDEECAICLDSLTVPVITHCAHVFCKPCICQVI 788
Query: 455 DH---NAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEEL-KERRKLYEEEMEELSN 510
+ +AKCPLC +N I E+ + + PEEL ++ K + E S
Sbjct: 789 QNEQPHAKCPLC--------------RNDIHEDNLLECPPEELARDSEKKSDMEWTSSSK 834
Query: 511 LN 512
+N
Sbjct: 835 IN 836
Score = 30.0 bits (66), Expect = 7.8
Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLCL---ERGRAADRRCALC 195
+C C L+ PV C H FCK C+ + +C LC
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLC 800
>gi|21071054 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 53.9 bits (128), Expect = 5e-07
Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 18/122 (14%)
Query: 395 NKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCL 454
N S D P + K + L SD ECA+C+ PV T C H FC C+ + +
Sbjct: 729 NGPSGNDTPEELRKKLIRKMKLILSSGSDEECAICLDSLTVPVITHCAHVFCKPCICQVI 788
Query: 455 DH---NAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEEL-KERRKLYEEEMEELSN 510
+ +AKCPLC +N I E+ + + PEEL ++ K + E S
Sbjct: 789 QNEQPHAKCPLC--------------RNDIHEDNLLECPPEELARDSEKKSDMEWTSSSK 834
Query: 511 LN 512
+N
Sbjct: 835 IN 836
Score = 30.0 bits (66), Expect = 7.8
Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLCL---ERGRAADRRCALC 195
+C C L+ PV C H FCK C+ + +C LC
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLC 800
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 53.5 bits (127), Expect = 7e-07
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 9/104 (8%)
Query: 398 SKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHN 457
+K++ Q K + + ++L+C +C F E VT C H+FC C+ +
Sbjct: 375 TKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRK 434
Query: 458 AKCPLCKDGLSQCLASRKYSKNVIMEELIAKF---LPEELKERR 498
+CP+C+ + S+ YS ++++ I K L E+KERR
Sbjct: 435 IECPICRKDIK----SKTYS--LVLDNCINKMVNNLSSEVKERR 472
Score = 33.5 bits (75), Expect = 0.71
Identities = 11/39 (28%), Positives = 19/39 (48%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALC 195
+C C + + V+L+C H+FC C+ C +C
Sbjct: 402 QCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPIC 440
>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
Length = 1884
Score = 52.4 bits (124), Expect = 1e-06
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 424 LECALCMRLFYEPVTTPCGHTFCLKCLERCLDHN---AKCPLCKDGLSQCLASRKYSKNV 480
LEC +C+ L EPV+T C H FC C+ + L+ ++CPLCK+ +++ +
Sbjct: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81
Query: 481 IMEELI 486
++EEL+
Sbjct: 82 LVEELL 87
Score = 34.3 bits (77), Expect = 0.41
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLC---LERGRAADRRCALC 195
+C C + +PVS C H FCK C L + +C LC
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLC 64
>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
Length = 699
Score = 52.4 bits (124), Expect = 1e-06
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 424 LECALCMRLFYEPVTTPCGHTFCLKCLERCLDHN---AKCPLCKDGLSQCLASRKYSKNV 480
LEC +C+ L EPV+T C H FC C+ + L+ ++CPLCK+ +++ +
Sbjct: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81
Query: 481 IMEELI 486
++EEL+
Sbjct: 82 LVEELL 87
Score = 34.3 bits (77), Expect = 0.41
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLC---LERGRAADRRCALC 195
+C C + +PVS C H FCK C L + +C LC
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLC 64
>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
Length = 759
Score = 52.4 bits (124), Expect = 1e-06
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 424 LECALCMRLFYEPVTTPCGHTFCLKCLERCLDHN---AKCPLCKDGLSQCLASRKYSKNV 480
LEC +C+ L EPV+T C H FC C+ + L+ ++CPLCK+ +++ +
Sbjct: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81
Query: 481 IMEELI 486
++EEL+
Sbjct: 82 LVEELL 87
Score = 34.3 bits (77), Expect = 0.41
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLC---LERGRAADRRCALC 195
+C C + +PVS C H FCK C L + +C LC
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLC 64
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 52.4 bits (124), Expect = 1e-06
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 424 LECALCMRLFYEPVTTPCGHTFCLKCLERCLDHN---AKCPLCKDGLSQCLASRKYSKNV 480
LEC +C+ L EPV+T C H FC C+ + L+ ++CPLCK+ +++ +
Sbjct: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81
Query: 481 IMEELI 486
++EEL+
Sbjct: 82 LVEELL 87
Score = 34.3 bits (77), Expect = 0.41
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLC---LERGRAADRRCALC 195
+C C + +PVS C H FCK C L + +C LC
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLC 64
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 52.4 bits (124), Expect = 1e-06
Identities = 39/125 (31%), Positives = 62/125 (49%), Gaps = 9/125 (7%)
Query: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEI 302
A L+ +GN + E E A+L+Y+E ++ + +LY+NR+Q Y LE +E AL D E
Sbjct: 106 ADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEW 165
Query: 303 ACKLRP--------MGFKDNLELPHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQE 354
A K MG K NL L + S E + + +VKG Q ++++
Sbjct: 166 ALKCDEKCTKAYFHMG-KANLALKNYSVSRECYKKILEINPKLQTQVKGYLNQVDLQEKA 224
Query: 355 EEEEK 359
+ +EK
Sbjct: 225 DLQEK 229
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 52.0 bits (123), Expect = 2e-06
Identities = 67/277 (24%), Positives = 104/277 (37%), Gaps = 33/277 (11%)
Query: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEI 302
A +L+ +GNRL+ R+ A Y A+ P + Y+NR+ Y ++ HE AL D
Sbjct: 26 AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRR 85
Query: 303 ACKLRPMGFKDNLELPHC----SSQEEAAAR---------------GDG--SSLMDPAKV 341
A +L K + L C S +EA A GD S+L K
Sbjct: 86 ALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKK 145
Query: 342 KGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKKRKHCQIESQEETGMPNKASKQD 401
+ + + QE E + S A+ + + +E +R H E +
Sbjct: 146 RWNSIEERRIHQESELHSY--LSRLIAAERERELEECQRNHEGDEDDSHVRAQQACIEAK 203
Query: 402 PPTDQGDKPALSLPL----ASFDASDLECA-LCMRLFYEPVTTPCGHTFCLKCLERCLDH 456
D L + D D C + L EP TP G T+ K +E L
Sbjct: 204 HDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQR 263
Query: 457 NAKC-PLCKDGLSQCLASRKYSKNVIMEELIAKFLPE 492
P+ + L+Q + N+ M+E+I F+ E
Sbjct: 264 VGHFDPVTRSPLTQ----EQLIPNLAMKEVIDAFISE 296
>gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]
Length = 493
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 415 PLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERC--LDHNAKCPLCKDGLSQCLA 472
P SF +L CA+C F + VT CGH FC C+ RC + + CP+CKD S
Sbjct: 11 PSRSFK-EELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADL 69
Query: 473 SRKYSKNVIMEELI 486
++ N ++E+L+
Sbjct: 70 RTNHTLNNLVEKLL 83
Score = 33.9 bits (76), Expect = 0.54
Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 21/90 (23%)
Query: 158 CRKCHGFLSDPVSLSCGHTFCKLCLER--GRAADRRCALCGVKLSALMVATGRARGARRA 215
C C+ D V+L CGH FC+ C+ R C +C + S
Sbjct: 21 CAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRAS--------------- 65
Query: 216 GQQPPPPLRVNVVLSGLLGKLFPGPARASQ 245
P LR N L+ L+ KL A ++
Sbjct: 66 ----PADLRTNHTLNNLVEKLLREEAEGAR 91
>gi|37595555 ring finger protein 125 [Homo sapiens]
Length = 232
Score = 51.2 bits (121), Expect = 3e-06
Identities = 22/52 (42%), Positives = 31/52 (59%), Gaps = 6/52 (11%)
Query: 414 LPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNA-KCPLCK 464
LP+ SFD CA+C+ + ++PV T CGH FC C+ L +N CP C+
Sbjct: 30 LPVTSFD-----CAVCLEVLHQPVRTRCGHVFCRSCIATSLKNNKWTCPYCR 76
Score = 35.8 bits (81), Expect = 0.14
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 11/60 (18%)
Query: 134 GTVAAEETGAAAAAAATE-----------VWDGFKCRKCHGFLSDPVSLSCGHTFCKLCL 182
G+V + ++G +A A+AT F C C L PV CGH FC+ C+
Sbjct: 2 GSVLSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSCI 61
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 50.8 bits (120), Expect = 4e-06
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 13/93 (13%)
Query: 421 ASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNV 480
++D C +C + E T CGH+FC KC+ + L+ N +CP C +
Sbjct: 131 SNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDN----------- 179
Query: 481 IMEELIAKFLPEEL-KERRKLYEEEMEELSNLN 512
++ L FL EL ++++ +EE+ +L + N
Sbjct: 180 -IDHLYPNFLVNELILKQKQRFEEKRFKLDHSN 211
Score = 34.7 bits (78), Expect = 0.32
Identities = 12/40 (30%), Positives = 18/40 (45%)
Query: 156 FKCRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALC 195
F C C + + CGH+FC C+ + + RC C
Sbjct: 134 FVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKC 173
>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
Length = 638
Score = 50.8 bits (120), Expect = 4e-06
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 14/72 (19%)
Query: 426 CALCMRLFYEPVTTPCGHTFCLKCLERCLDHN-----------AKCPLCKDGLSQCLASR 474
C +C+ EPVT PCGH FCL CL H A+CPLC++ L R
Sbjct: 9 CPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQLR 68
Query: 475 KYSKNVIMEELI 486
KN + EL+
Sbjct: 69 ---KNHTLSELL 77
Score = 35.4 bits (80), Expect = 0.19
Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 11/51 (21%)
Query: 156 FKCRKCHGFLSDPVSLSCGHTFCKLCL-----------ERGRAADRRCALC 195
F C C L +PV+L CGH FC CL G RC LC
Sbjct: 7 FSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLC 57
>gi|62865604 tripartite motif protein 31 [Homo sapiens]
Length = 425
Score = 50.1 bits (118), Expect = 7e-06
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 426 CALCMRLFYEPVTTPCGHTFCLKCLERCLDHNA---KCPLCKDGL-SQCLASRKYSKNVI 481
C +C+ + +PVT CGH FCLKC+ + + + KCPLCK + + +N++
Sbjct: 16 CPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSVRKNAIRFNSLLRNLV 75
Query: 482 MEELIAKFLPEELKERRK 499
E I E++ +RK
Sbjct: 76 --EKIQALQASEVQSKRK 91
Score = 32.0 bits (71), Expect = 2.1
Identities = 11/25 (44%), Positives = 14/25 (56%)
Query: 158 CRKCHGFLSDPVSLSCGHTFCKLCL 182
C C L PV++ CGH FC C+
Sbjct: 16 CPICLDILQKPVTIDCGHNFCLKCI 40
>gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens]
Length = 1066
Score = 50.1 bits (118), Expect = 7e-06
Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 423 DLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPL-CKDGLS 468
DL+CALC ++ +P+TTPCGH FC C+ + CP C+ LS
Sbjct: 15 DLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRLS 61
Score = 39.3 bits (90), Expect = 0.013
Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRC-ALCGVKLSA 201
KC CH L DP++ CGH FC C+ + C A C +LSA
Sbjct: 17 KCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRLSA 62
>gi|37655169 ring finger protein 135 isoform 2 [Homo sapiens]
Length = 210
Score = 49.7 bits (117), Expect = 1e-05
Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 7/71 (9%)
Query: 423 DLECALCMRLFYEPVTTPCGHTFCLKCLERCLD----HNAKCPLCKDGLSQCLASRKYSK 478
DL C +C L P T PCGH+FC CLE CP C+ G +Q K
Sbjct: 18 DLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQ---QPHLRK 74
Query: 479 NVIMEELIAKF 489
N ++++L K+
Sbjct: 75 NTLLQDLADKY 85
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/95 (33%), Positives = 37/95 (38%), Gaps = 25/95 (26%)
Query: 148 AATEVW---DGFKCRKCHGFLSDPVSLSCGHTFCKLCLER--GRAADRR--CALCGVKLS 200
+A VW D C C G L P +L CGH+FC+ CLE G RR C C
Sbjct: 8 SAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTC----- 62
Query: 201 ALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGK 235
R G P LR N +L L K
Sbjct: 63 -------------RQGAAQQPHLRKNTLLQDLADK 84
>gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
Length = 432
Score = 49.7 bits (117), Expect = 1e-05
Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 7/71 (9%)
Query: 423 DLECALCMRLFYEPVTTPCGHTFCLKCLERCLD----HNAKCPLCKDGLSQCLASRKYSK 478
DL C +C L P T PCGH+FC CLE CP C+ G +Q K
Sbjct: 18 DLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQ---QPHLRK 74
Query: 479 NVIMEELIAKF 489
N ++++L K+
Sbjct: 75 NTLLQDLADKY 85
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/95 (33%), Positives = 37/95 (38%), Gaps = 25/95 (26%)
Query: 148 AATEVW---DGFKCRKCHGFLSDPVSLSCGHTFCKLCLER--GRAADRR--CALCGVKLS 200
+A VW D C C G L P +L CGH+FC+ CLE G RR C C
Sbjct: 8 SAVPVWLAEDDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTC----- 62
Query: 201 ALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGK 235
R G P LR N +L L K
Sbjct: 63 -------------RQGAAQQPHLRKNTLLQDLADK 84
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 49.7 bits (117), Expect = 1e-05
Identities = 17/43 (39%), Positives = 26/43 (60%)
Query: 421 ASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLC 463
++D C +C + E T CGH+FC KC+ + L+ N +CP C
Sbjct: 131 SNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKC 173
Score = 34.7 bits (78), Expect = 0.32
Identities = 12/40 (30%), Positives = 18/40 (45%)
Query: 156 FKCRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALC 195
F C C + + CGH+FC C+ + + RC C
Sbjct: 134 FVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKC 173
>gi|38679905 tripartite motif-containing 65 [Homo sapiens]
Length = 517
Score = 49.7 bits (117), Expect = 1e-05
Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 424 LECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAK-CPLCKD 465
L CA+C+ L+ +PVT PCGH FC C+ D K CP C++
Sbjct: 10 LTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKACPECRE 52
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/95 (34%), Positives = 40/95 (42%), Gaps = 17/95 (17%)
Query: 148 AATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALCGVKLSALMVATG 207
AA + + C C G DPV+L CGH FC C+ R RC G
Sbjct: 2 AAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACI---RDWWDRC--------------G 44
Query: 208 RARGARRAGQQPPPPLRVNVVLSGLLGKLFPGPAR 242
+A R LR NV LSG+L + GPAR
Sbjct: 45 KACPECREPFPDGAELRRNVALSGVLEVVRAGPAR 79
>gi|7110679 tetratricopeptide repeat domain 33 [Homo sapiens]
Length = 262
Score = 49.7 bits (117), Expect = 1e-05
Identities = 24/67 (35%), Positives = 40/67 (59%)
Query: 242 RASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAE 301
++ QL+ EG L ++ A+ K++EA++L PND LY +SQ+ +L A+H AE
Sbjct: 58 KSKQLKDEGASLAENKRYREAIQKWDEALQLTPNDATLYEMKSQVLMSLHEMFPAVHAAE 117
Query: 302 IACKLRP 308
+A + P
Sbjct: 118 MAVQQNP 124
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 49.3 bits (116), Expect = 1e-05
Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 9/139 (6%)
Query: 213 RRAGQQPPPPLRVNVVLSGLLGKLFP-GP----ARASQLRHEGNRLYRERQVEAALLKYN 267
RR + PP + + + +G+ P GP A + + N+ + A++ YN
Sbjct: 23 RREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYN 82
Query: 268 EAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEIACKLRPMG----FKDNLELPHCSSQ 323
EA+ + P + +LYSNRS Y ++ ++ AL DA A L P F+ + L +
Sbjct: 83 EALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRH 142
Query: 324 EEAAARGDGSSLMDPAKVK 342
+A A DP ++
Sbjct: 143 ADALAAFASGLAQDPKSLQ 161
>gi|22749269 ring finger protein 129 [Homo sapiens]
Length = 471
Score = 49.3 bits (116), Expect = 1e-05
Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 9/90 (10%)
Query: 426 CALCMRLFYEPVTTPCGHTFCLKCLE---RCLDHNAKCPLCKDGLSQCLASRKYSKNVIM 482
C +C+ +PVT CGH FC CL + LD CP+C+ C + + +N +
Sbjct: 16 CPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCR----FCFPYKSFRRNPQL 71
Query: 483 EEL--IAKFLPEELKERRKLYEEEMEELSN 510
L IAK L +R++ E M E N
Sbjct: 72 RNLTEIAKQLQIRRSKRKRQKENAMCEKHN 101
Score = 38.1 bits (87), Expect = 0.029
Identities = 13/25 (52%), Positives = 18/25 (72%)
Query: 158 CRKCHGFLSDPVSLSCGHTFCKLCL 182
C C +L DPV+++CGH FC+ CL
Sbjct: 16 CPICLEYLKDPVTINCGHNFCRSCL 40
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 48.5 bits (114), Expect = 2e-05
Identities = 23/67 (34%), Positives = 39/67 (58%)
Query: 242 RASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAE 301
+ ++L+ +GN+ ++ AL Y+EA+KL P++H+LYSNRS Y ++ A D
Sbjct: 3 QVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGC 62
Query: 302 IACKLRP 308
L+P
Sbjct: 63 KTVDLKP 69
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/73 (34%), Positives = 37/73 (50%)
Query: 240 PARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHD 299
P A + +++GN +++ A+ Y EA+K P D LYSNR+ Y L + AL D
Sbjct: 357 PDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKD 416
Query: 300 AEIACKLRPMGFK 312
E +L P K
Sbjct: 417 CEECIQLEPTFIK 429
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,482,532
Number of Sequences: 37866
Number of extensions: 1548710
Number of successful extensions: 10679
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 283
Number of HSP's successfully gapped in prelim test: 244
Number of HSP's that attempted gapping in prelim test: 9646
Number of HSP's gapped (non-prelim): 1238
length of query: 718
length of database: 18,247,518
effective HSP length: 110
effective length of query: 608
effective length of database: 14,082,258
effective search space: 8562012864
effective search space used: 8562012864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.