Search of human proteins with 37537710

Search of human proteins with 37537710

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37537710 La ribonucleoprotein domain family, member 6
isoform 1 [Homo sapiens]
         (491 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37537710 La ribonucleoprotein domain family, member 6 isoform...   990   0.0  
gi|37537706 La ribonucleoprotein domain family, member 6 isoform...   136   4e-32
gi|109809739 La ribonucleoprotein domain family, member 7 [Homo ...    80   4e-15
gi|109809741 La ribonucleoprotein domain family, member 7 [Homo ...    80   4e-15
gi|10835067 autoantigen La [Homo sapiens]                              57   4e-08
gi|61102725 la related protein isoform 2 [Homo sapiens]                54   4e-07
gi|39725634 la related protein isoform 1 [Homo sapiens]                54   4e-07
gi|30061565 La ribonucleoprotein domain family member 2 isoform ...    53   7e-07
gi|30061569 La ribonucleoprotein domain family member 2 isoform ...    53   7e-07
gi|30061567 La ribonucleoprotein domain family member 2 isoform ...    53   7e-07
gi|40353738 c-Mpl binding protein isoform a [Homo sapiens]             45   1e-04
gi|40353736 c-Mpl binding protein isoform c [Homo sapiens]             45   1e-04
gi|40353740 c-Mpl binding protein isoform b [Homo sapiens]             45   1e-04
gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo s...    40   0.005
gi|57634536 La ribonucleoprotein domain family, member 4B [Homo ...    39   0.011
gi|239753842 PREDICTED: similar to hCG2040199 [Homo sapiens]           39   0.011
gi|169166778 PREDICTED: similar to hCG2040199 [Homo sapiens]           39   0.011
gi|169166363 PREDICTED: similar to hCG2040199 [Homo sapiens]           39   0.011
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap...    38   0.024
gi|44680141 BTB (POZ) domain containing 5 [Homo sapiens]               38   0.024
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    37   0.053
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    37   0.053
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    37   0.053
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    36   0.070
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    36   0.070
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor...    36   0.091
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor...    36   0.091
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    35   0.12 
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    35   0.12 
gi|5453567 craniofacial development protein 1 [Homo sapiens]           35   0.12 

>gi|37537710 La ribonucleoprotein domain family, member 6 isoform 1
           [Homo sapiens]
          Length = 491

 Score =  990 bits (2560), Expect = 0.0
 Identities = 491/491 (100%), Positives = 491/491 (100%)

Query: 1   MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEE 60
           MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEE
Sbjct: 1   MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEE 60

Query: 61  EPSRGHSGTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVR 120
           EPSRGHSGTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVR
Sbjct: 61  EPSRGHSGTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVR 120

Query: 121 RNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNEN 180
           RNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNEN
Sbjct: 121 RNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNEN 180

Query: 181 LPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELP 240
           LPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELP
Sbjct: 181 LPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELP 240

Query: 241 PDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKP 300
           PDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKP
Sbjct: 241 PDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKP 300

Query: 301 AKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNK 360
           AKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNK
Sbjct: 301 AKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNK 360

Query: 361 LSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYS 420
           LSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYS
Sbjct: 361 LSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYS 420

Query: 421 SDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGPDNTRG 480
           SDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGPDNTRG
Sbjct: 421 SDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGPDNTRG 480

Query: 481 FHGHERSRACV 491
           FHGHERSRACV
Sbjct: 481 FHGHERSRACV 491


>gi|37537706 La ribonucleoprotein domain family, member 6 isoform
          2 [Homo sapiens]
          Length = 93

 Score =  136 bits (343), Expect = 4e-32
 Identities = 66/66 (100%), Positives = 66/66 (100%)

Query: 1  MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEE 60
          MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEE
Sbjct: 1  MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEE 60

Query: 61 EPSRGH 66
          EPSRGH
Sbjct: 61 EPSRGH 66


>gi|109809739 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 72/277 (25%), Positives = 127/277 (45%), Gaps = 42/277 (15%)

Query: 77  EREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFK 136
           +++++E++ +   ++++  +  Q++F+F D NL KD FL + + +++ GYV + LL SF 
Sbjct: 19  KKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFN 78

Query: 137 KVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNENLPSKMLLVYDLYLSPK 196
           K+K LT D +  A AL+ S V+EL+ +  ++RR  P+   P +        VY + L PK
Sbjct: 79  KMKKLTTDGKLIARALRSSAVVELDLEGTRIRRKKPLGERPKD---EDERTVY-VELLPK 134

Query: 197 LWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQ 256
                       V    +E   ++FG  G +  + I                 Y   G  
Sbjct: 135 -----------NVNHSWIE---RVFGKCGNVVYISI---------------PHYKSTGDP 165

Query: 257 E-CAIVEFEEVEAAIKAHEFMIT---ESQGKENMKAVLIGMKP-PKKKPAKDKNHDEEPT 311
           +  A VEFE  E A KA EF+     E+  K  +    +  KP P  +  ++K   ++  
Sbjct: 166 KGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIPALRVVEEKKKKKKKK 225

Query: 312 ASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTS 348
             +    ++  + E +    D S+ + S    S PTS
Sbjct: 226 GRMKKEDNIQAKEENM----DTSNTSISKMKRSRPTS 258


>gi|109809741 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 72/277 (25%), Positives = 127/277 (45%), Gaps = 42/277 (15%)

Query: 77  EREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFK 136
           +++++E++ +   ++++  +  Q++F+F D NL KD FL + + +++ GYV + LL SF 
Sbjct: 19  KKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIEKSRDGYVDISLLVSFN 78

Query: 137 KVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNENLPSKMLLVYDLYLSPK 196
           K+K LT D +  A AL+ S V+EL+ +  ++RR  P+   P +        VY + L PK
Sbjct: 79  KMKKLTTDGKLIARALRSSAVVELDLEGTRIRRKKPLGERPKD---EDERTVY-VELLPK 134

Query: 197 LWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQ 256
                       V    +E   ++FG  G +  + I                 Y   G  
Sbjct: 135 -----------NVNHSWIE---RVFGKCGNVVYISI---------------PHYKSTGDP 165

Query: 257 E-CAIVEFEEVEAAIKAHEFMIT---ESQGKENMKAVLIGMKP-PKKKPAKDKNHDEEPT 311
           +  A VEFE  E A KA EF+     E+  K  +    +  KP P  +  ++K   ++  
Sbjct: 166 KGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIPALRVVEEKKKKKKKK 225

Query: 312 ASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTS 348
             +    ++  + E +    D S+ + S    S PTS
Sbjct: 226 GRMKKEDNIQAKEENM----DTSNTSISKMKRSRPTS 258


>gi|10835067 autoantigen La [Homo sapiens]
          Length = 408

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 29/83 (34%), Positives = 51/83 (61%), Gaps = 3/83 (3%)

Query: 95  KLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKY 154
           K+  QIE+YF D NL +D FL + ++ ++ G+V ++++  F ++  LT D+     AL  
Sbjct: 16  KICHQIEYYFGDFNLPRDKFLKEQIKLDE-GWVPLEIMIKFNRLNRLTTDFNVIVEALSK 74

Query: 155 S--VVLELNEDHRKVRRTTPVPL 175
           S   ++E++ED  K+RR+   PL
Sbjct: 75  SKAELMEISEDKTKIRRSPSKPL 97


>gi|61102725 la related protein isoform 2 [Homo sapiens]
          Length = 1096

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 34/82 (41%), Positives = 53/82 (64%), Gaps = 5/82 (6%)

Query: 89  DEELIKKLVD-QIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRT 147
           D+EL+K  +  QIE+YFS +NLE+D FL + +  +  G++ + L+ SF +V+ LT D   
Sbjct: 399 DQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDAD--GFLPITLIASFHRVQALTTDISL 456

Query: 148 TAHALKYSVVLELNEDHRKVRR 169
              ALK S V+E+ ++  KVRR
Sbjct: 457 IFAALKDSKVVEIVDE--KVRR 476


>gi|39725634 la related protein isoform 1 [Homo sapiens]
          Length = 1019

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 34/82 (41%), Positives = 53/82 (64%), Gaps = 5/82 (6%)

Query: 89  DEELIKKLVD-QIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRT 147
           D+EL+K  +  QIE+YFS +NLE+D FL + +  +  G++ + L+ SF +V+ LT D   
Sbjct: 322 DQELLKDYIKRQIEYYFSVDNLERDFFLRRKMDAD--GFLPITLIASFHRVQALTTDISL 379

Query: 148 TAHALKYSVVLELNEDHRKVRR 169
              ALK S V+E+ ++  KVRR
Sbjct: 380 IFAALKDSKVVEIVDE--KVRR 399


>gi|30061565 La ribonucleoprotein domain family member 2 isoform 2
           [Homo sapiens]
          Length = 522

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 32/100 (32%), Positives = 58/100 (58%), Gaps = 6/100 (6%)

Query: 87  PPDEELIKKLVD-QIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDW 145
           P +E L+K+ +  QIE+YFS ENLE+D FL    + ++ G++ + L+  F++V+ LT + 
Sbjct: 209 PVEEALLKEYIKRQIEYYFSVENLERDFFL--RGKMDEQGFLPISLIAGFQRVQALTTNL 266

Query: 146 RTTAHALKYSVVLELNEDHRKVR---RTTPVPLFPNENLP 182
                ALK S  +E+ ++  + +      P+P  P  ++P
Sbjct: 267 NLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGPPPRSVP 306


>gi|30061569 La ribonucleoprotein domain family member 2 isoform 3
           [Homo sapiens]
          Length = 358

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 32/100 (32%), Positives = 58/100 (58%), Gaps = 6/100 (6%)

Query: 87  PPDEELIKKLVD-QIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDW 145
           P +E L+K+ +  QIE+YFS ENLE+D FL    + ++ G++ + L+  F++V+ LT + 
Sbjct: 209 PVEEALLKEYIKRQIEYYFSVENLERDFFL--RGKMDEQGFLPISLIAGFQRVQALTTNL 266

Query: 146 RTTAHALKYSVVLELNEDHRKVR---RTTPVPLFPNENLP 182
                ALK S  +E+ ++  + +      P+P  P  ++P
Sbjct: 267 NLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGPPPRSVP 306


>gi|30061567 La ribonucleoprotein domain family member 2 isoform 1
           [Homo sapiens]
          Length = 914

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 32/100 (32%), Positives = 58/100 (58%), Gaps = 6/100 (6%)

Query: 87  PPDEELIKKLVD-QIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDW 145
           P +E L+K+ +  QIE+YFS ENLE+D FL    + ++ G++ + L+  F++V+ LT + 
Sbjct: 209 PVEEALLKEYIKRQIEYYFSVENLERDFFL--RGKMDEQGFLPISLIAGFQRVQALTTNL 266

Query: 146 RTTAHALKYSVVLELNEDHRKVR---RTTPVPLFPNENLP 182
                ALK S  +E+ ++  + +      P+P  P  ++P
Sbjct: 267 NLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGPPPRSVP 306


>gi|40353738 c-Mpl binding protein isoform a [Homo sapiens]
          Length = 724

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 20/111 (18%)

Query: 90  EELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTA 149
           E+L + L  Q+EF FS ENL KD +L+  +  ++  ++ +  + + +++K LT D     
Sbjct: 117 EDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQ--FIPIWTVANMEEIKKLTTDPDLIL 174

Query: 150 HALKYSVVLELNEDHRKVR--------------RTTPVP----LFPNENLP 182
             L+ S +++++E   KVR               TTP+     LF +EN P
Sbjct: 175 EVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCP 225


>gi|40353736 c-Mpl binding protein isoform c [Homo sapiens]
          Length = 653

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 20/111 (18%)

Query: 90  EELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTA 149
           E+L + L  Q+EF FS ENL KD +L+  +  ++  ++ +  + + +++K LT D     
Sbjct: 117 EDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQ--FIPIWTVANMEEIKKLTTDPDLIL 174

Query: 150 HALKYSVVLELNEDHRKVR--------------RTTPVP----LFPNENLP 182
             L+ S +++++E   KVR               TTP+     LF +EN P
Sbjct: 175 EVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCP 225


>gi|40353740 c-Mpl binding protein isoform b [Homo sapiens]
          Length = 730

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 20/111 (18%)

Query: 90  EELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTA 149
           E+L + L  Q+EF FS ENL KD +L+  +  ++  ++ +  + + +++K LT D     
Sbjct: 123 EDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQ--FIPIWTVANMEEIKKLTTDPDLIL 180

Query: 150 HALKYSVVLELNEDHRKVR--------------RTTPVP----LFPNENLP 182
             L+ S +++++E   KVR               TTP+     LF +EN P
Sbjct: 181 EVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCP 231


>gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo
           sapiens]
          Length = 1283

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 58/194 (29%), Positives = 82/194 (42%), Gaps = 18/194 (9%)

Query: 282 GKENMKAVLIGMKPPKKK--PAKDK-NHDEEPTASI--HLNKSLNKRVEELQYMGDESSA 336
           G+E  + +L+G+KP +    PA+D     E+ TA++      SLN   E++Q    E+  
Sbjct: 460 GREK-EGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNL-FEDVQITEPEAEP 517

Query: 337 NSSSDPESNPTSPMAGRRHAATNKL--SPSGHQNLFL-SPNASPCTSPWSSPLAQRKG-V 392
            S S+P    +SP A +  A   +L  SP       L SP  SP + P   PL    G  
Sbjct: 518 ESKSEPRPPISSPRAPQTRAVKPRLEVSPEAQPTARLPSPTDSPSSLP---PLPSSSGQA 574

Query: 393 SRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSP 452
           S  S L        S SP +F      SS  +   S S  +      + G Q KS G   
Sbjct: 575 SVPSELGHGADTQSSESPSVF---SSLSSPIAAPISTSTPIESWPLVDRG-QAKSEGPPL 630

Query: 453 LLSRKMQTADGLPV 466
           L   ++QT    PV
Sbjct: 631 LPKAELQTESLTPV 644


>gi|57634536 La ribonucleoprotein domain family, member 4B [Homo
           sapiens]
          Length = 738

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 30/170 (17%)

Query: 33  DEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHS--GTTASGGENEREDLEQEWKPPDE 90
           D ++G E     DP     P   +A    PS   S    + +GG   + D +++      
Sbjct: 103 DGDQGHENAALPDPQES-DPADMNALALGPSEYDSLPENSETGGNESQPDSQED----PR 157

Query: 91  ELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAH 150
           E++KK    +EF  S ENL  D +L+  +  ++  YV +  + +   +K L+ D      
Sbjct: 158 EVLKKT---LEFCLSRENLASDMYLISQMDSDQ--YVPITTVANLDHIKKLSTDVDLIVE 212

Query: 151 ALKYSVVLELNEDHRKVR--------------RTTPV----PLFPNENLP 182
            L+   +++++E   KVR               +TPV     LF  +NLP
Sbjct: 213 VLRSLPLVQVDEKGEKVRPNQNRCIVILREISESTPVEEVEALFKGDNLP 262


>gi|239753842 PREDICTED: similar to hCG2040199 [Homo sapiens]
          Length = 315

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 6/80 (7%)

Query: 89  DEELIKKLVD-QIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRT 147
           +E L+K+ +  QIE YF+ EN E+D FL    +R +   + + L+  F++V+ LT +  T
Sbjct: 217 EEALLKECIKRQIEHYFNAENSERDYFL--RGKRGEQDSLPIFLIAGFQRVQALTTNLIT 274

Query: 148 TAHALKYSVVLE-LNEDHRK 166
              ALK S  +E +NE  RK
Sbjct: 275 --EALKDSTEVEIMNEKMRK 292


>gi|169166778 PREDICTED: similar to hCG2040199 [Homo sapiens]
          Length = 315

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 6/80 (7%)

Query: 89  DEELIKKLVD-QIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRT 147
           +E L+K+ +  QIE YF+ EN E+D FL    +R +   + + L+  F++V+ LT +  T
Sbjct: 217 EEALLKECIKRQIEHYFNAENSERDYFL--RGKRGEQDSLPIFLIAGFQRVQALTTNLIT 274

Query: 148 TAHALKYSVVLE-LNEDHRK 166
              ALK S  +E +NE  RK
Sbjct: 275 --EALKDSTEVEIMNEKMRK 292


>gi|169166363 PREDICTED: similar to hCG2040199 [Homo sapiens]
          Length = 315

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 6/80 (7%)

Query: 89  DEELIKKLVD-QIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRT 147
           +E L+K+ +  QIE YF+ EN E+D FL    +R +   + + L+  F++V+ LT +  T
Sbjct: 217 EEALLKECIKRQIEHYFNAENSERDYFL--RGKRGEQDSLPIFLIAGFQRVQALTTNLIT 274

Query: 148 TAHALKYSVVLE-LNEDHRK 166
              ALK S  +E +NE  RK
Sbjct: 275 --EALKDSTEVEIMNEKMRK 292


>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo
           sapiens]
          Length = 1747

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 49/184 (26%), Positives = 72/184 (39%), Gaps = 26/184 (14%)

Query: 244 RRISSRYSQVGTQECAIVEFEEVEAAIKAHE------FMITESQGKENMKAVLIGMKPPK 297
           R + +  SQ   Q   I    E+   IK H+      F  T S  K    A   G+  P+
Sbjct: 309 RDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSGLASPR 368

Query: 298 --KKPAKDKNHDEEPTASIHLNKSLNKRVEEL--QYMGDESSANSSSDPESNPTSPMAGR 353
             ++ A D N   E   +     SL     +L  Q + +E   +  +D ESN + P+AGR
Sbjct: 369 PLQRSASDINLKGEAQPAASPGPSLRSLPHQLLLQRLQEEKDRDRDADQESNISGPLAGR 428

Query: 354 RHAATNKLS-----PSGHQNLFLSPNASPCT---------SPWSSPLAQRKGVSRKSPLA 399
             A  +K+S     P G     L P  +P +         +P + P    +G  RK   A
Sbjct: 429 --AGQSKISDPGPGPGGVGGAPLPPPGAPRSCIRIRARFPAPPAPPAPPPRGPKRKLYSA 486

Query: 400 EEGR 403
             GR
Sbjct: 487 VPGR 490


>gi|44680141 BTB (POZ) domain containing 5 [Homo sapiens]
          Length = 571

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 100 IEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAH----ALKYS 155
           +E +   +  E+  +L + +   +L  +SVK LT   +  HL RD RT  H    ALKY 
Sbjct: 202 LESWIKYDVQERQKYLAQLLNSVRLPLLSVKFLTRLYEANHLIRDDRTCKHLLNEALKYH 261

Query: 156 VVLELNEDHRKVRRTTP 172
            + E    H+ V  T P
Sbjct: 262 FMPEHRLSHQTVLMTRP 278


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
            [Homo sapiens]
          Length = 2000

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 6/131 (4%)

Query: 320  LNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNKLSPSGHQNLFLSPNASPCT 379
            + K+V+E +++    S      P+ +  S  + R  + T K SP+  +    S   SPCT
Sbjct: 1498 VKKKVQEFEHINGRWSMPELM-PDPSADSKRSSRASSPT-KTSPTTPE---ASATNSPCT 1552

Query: 380  SPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTPSGSPWVRRRRQ- 438
            S  ++P    KG   ++PL +E   N    PE   +  +     +  PS +P +  R + 
Sbjct: 1553 SKPATPAPSEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEP 1612

Query: 439  AEMGTQEKSPG 449
             ++  +++ PG
Sbjct: 1613 RKIPLEDEVPG 1623


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
            [Homo sapiens]
          Length = 1966

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 6/131 (4%)

Query: 320  LNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNKLSPSGHQNLFLSPNASPCT 379
            + K+V+E +++    S      P+ +  S  + R  + T K SP+  +    S   SPCT
Sbjct: 1498 VKKKVQEFEHINGRWSMPELM-PDPSADSKRSSRASSPT-KTSPTTPE---ASATNSPCT 1552

Query: 380  SPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTPSGSPWVRRRRQ- 438
            S  ++P    KG   ++PL +E   N    PE   +  +     +  PS +P +  R + 
Sbjct: 1553 SKPATPAPSEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEP 1612

Query: 439  AEMGTQEKSPG 449
             ++  +++ PG
Sbjct: 1613 RKIPLEDEVPG 1623


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
            [Homo sapiens]
          Length = 2059

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 6/131 (4%)

Query: 320  LNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNKLSPSGHQNLFLSPNASPCT 379
            + K+V+E +++    S      P+ +  S  + R  + T K SP+  +    S   SPCT
Sbjct: 1557 VKKKVQEFEHINGRWSMPELM-PDPSADSKRSSRASSPT-KTSPTTPE---ASATNSPCT 1611

Query: 380  SPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTPSGSPWVRRRRQ- 438
            S  ++P    KG   ++PL +E   N    PE   +  +     +  PS +P +  R + 
Sbjct: 1612 SKPATPAPSEKGEGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEP 1671

Query: 439  AEMGTQEKSPG 449
             ++  +++ PG
Sbjct: 1672 RKIPLEDEVPG 1682


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 36.2 bits (82), Expect = 0.070
 Identities = 49/198 (24%), Positives = 74/198 (37%), Gaps = 29/198 (14%)

Query: 277 ITESQGKENMKAVLIGMKPPKKKPAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSA 336
           + +S  KE+  + L   K  K++  K  + D         +KS  KR     Y   +S  
Sbjct: 166 VAKSSSKESRSSKLHKEKTRKERELKSGHKDR--------SKSHRKRETPKSYKTVDSPK 217

Query: 337 NSSSDPE------SNPTSPMAGRRHAATNKLSPS------GHQNLFLSPNASP----CTS 380
             S  P       S      +G  +     LSPS       + +   SP ++      + 
Sbjct: 218 RRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSP 277

Query: 381 PWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTP-SGSPWVRRRRQA 439
           P+  P A +      SP +   R   S SP   R+   Y    S +  S SP+ RRR  +
Sbjct: 278 PYKEPSAYQSSTRSPSPYSRRQR---SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSS 334

Query: 440 EMGTQEKSPGTSPLLSRK 457
                ++S   SPL SRK
Sbjct: 335 PF-LSKRSLSRSPLPSRK 351


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 36.2 bits (82), Expect = 0.070
 Identities = 49/198 (24%), Positives = 74/198 (37%), Gaps = 29/198 (14%)

Query: 277 ITESQGKENMKAVLIGMKPPKKKPAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSA 336
           + +S  KE+  + L   K  K++  K  + D         +KS  KR     Y   +S  
Sbjct: 166 VAKSSSKESRSSKLHKEKTRKERELKSGHKDR--------SKSHRKRETPKSYKTVDSPK 217

Query: 337 NSSSDPE------SNPTSPMAGRRHAATNKLSPS------GHQNLFLSPNASP----CTS 380
             S  P       S      +G  +     LSPS       + +   SP ++      + 
Sbjct: 218 RRSRSPHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSP 277

Query: 381 PWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTP-SGSPWVRRRRQA 439
           P+  P A +      SP +   R   S SP   R+   Y    S +  S SP+ RRR  +
Sbjct: 278 PYKEPSAYQSSTRSPSPYSRRQR---SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSS 334

Query: 440 EMGTQEKSPGTSPLLSRK 457
                ++S   SPL SRK
Sbjct: 335 PF-LSKRSLSRSPLPSRK 351


>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
           [Homo sapiens]
          Length = 709

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 48/193 (24%), Positives = 78/193 (40%), Gaps = 23/193 (11%)

Query: 296 PKKKPAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRH 355
           PK++   D+     PT++ +  K+ +   E  +   D  S   +S     P SP+ G   
Sbjct: 403 PKQRRFSDQAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLER 462

Query: 356 AATNKLSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRK 415
             T   +PS +  L  S N S      +SPL +R  + + S   + G+   ST+P+    
Sbjct: 463 KKTTP-TPSTNSVLSTSTNRSR-----NSPLLERASLGQAS--IQNGK--DSTAPQ---- 508

Query: 416 CMDYSSDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGP 475
            +  +S S+   S S     R     G   +S   +  L R+++    LP GV   P  P
Sbjct: 509 RVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQL-RQVRDQQNLPYGV--TPASP 565

Query: 476 DNTRGFHGHERSR 488
                  GH + R
Sbjct: 566 S------GHSQGR 572


>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
           [Homo sapiens]
          Length = 724

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 48/193 (24%), Positives = 78/193 (40%), Gaps = 23/193 (11%)

Query: 296 PKKKPAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRH 355
           PK++   D+     PT++ +  K+ +   E  +   D  S   +S     P SP+ G   
Sbjct: 403 PKQRRFSDQAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLER 462

Query: 356 AATNKLSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRK 415
             T   +PS +  L  S N S      +SPL +R  + + S   + G+   ST+P+    
Sbjct: 463 KKTTP-TPSTNSVLSTSTNRSR-----NSPLLERASLGQAS--IQNGK--DSTAPQ---- 508

Query: 416 CMDYSSDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGP 475
            +  +S S+   S S     R     G   +S   +  L R+++    LP GV   P  P
Sbjct: 509 RVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQL-RQVRDQQNLPYGV--TPASP 565

Query: 476 DNTRGFHGHERSR 488
                  GH + R
Sbjct: 566 S------GHSQGR 572


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 24/69 (34%), Positives = 28/69 (40%), Gaps = 5/69 (7%)

Query: 23  QEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHSGTTASGGENEREDLE 82
           +E E   E E E EG E  G G        G G   EEE            GE E E+ E
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE-----GEGEGEDGEGEGEEEE 952

Query: 83  QEWKPPDEE 91
            EW+  +EE
Sbjct: 953 GEWEGEEEE 961



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 8/69 (11%)

Query: 26  EDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGH----SGTTASGGENEREDL 81
           E+ +E E EEEG E  G G+       G G   EE    G      G     GE E E+ 
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEE----EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915

Query: 82  EQEWKPPDE 90
           E E K  +E
Sbjct: 916 EGEGKGEEE 924



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 17/90 (18%)

Query: 3   QSGGEARPGPKTAVQIRVAIQEAEDVDELEDEE-EGAETRGAGDPARYLSPGWGSASEEE 61
           + GGE   G          ++E +   E E+EE EG E  G G+             EEE
Sbjct: 809 EEGGEVEGGE---------VEEGKGEREEEEEEGEGEEEEGEGEEEE-------GEGEEE 852

Query: 62  PSRGHSGTTASGGENEREDLEQEWKPPDEE 91
              G        GE E E  E E +  +EE
Sbjct: 853 EGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 5/68 (7%)

Query: 23  QEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHSGTTASGGENEREDLE 82
           +E E+ +  E+E EG E  G G+       G     EEE   G        GE E E+ E
Sbjct: 828 EEEEEGEGEEEEGEGEEEEGEGEEEEGEGKG-----EEEGEEGEGEEEGEEGEGEGEEEE 882

Query: 83  QEWKPPDE 90
            E +  +E
Sbjct: 883 GEGEGEEE 890



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 19/58 (32%), Positives = 22/58 (37%)

Query: 23   QEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHSGTTASGGENERED 80
            +E E   E E E EG E  G G+       G     EEE      G     GE E E+
Sbjct: 960  EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 23   QEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHSGTTASGGENEREDLE 82
            +E E   E E+ EE  E  G G+       G G   EE    G        GE E E+ E
Sbjct: 984  EEGEGEGEEEEGEEEGEEEGEGEEE---GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040

Query: 83   QEWKPPDEE 91
            +E +  ++E
Sbjct: 1041 EEGEEREKE 1049



 Score = 29.6 bits (65), Expect = 6.5
 Identities = 19/61 (31%), Positives = 24/61 (39%)

Query: 23   QEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHSGTTASGGENEREDLE 82
            +E E   E E+E EG    G G+       G G   E E      G     GE E E+ E
Sbjct: 958  EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017

Query: 83   Q 83
            +
Sbjct: 1018 E 1018



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 12/80 (15%)

Query: 24  EAEDVDELEDEEEGAETRG--AGDPARYLSPGWGSASEEEPSRGHSGTTASGGE------ 75
           E E+V+   ++EEG   +   AG   +    G     EEE + G       GGE      
Sbjct: 760 EGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEV 819

Query: 76  ----NEREDLEQEWKPPDEE 91
                ERE+ E+E +  +EE
Sbjct: 820 EEGKGEREEEEEEGEGEEEE 839


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 42/170 (24%), Positives = 60/170 (35%), Gaps = 10/170 (5%)

Query: 297 KKKPAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHA 356
           +K P +DK  +EE  A     K   K   E      +SS  S  D E++    MA ++  
Sbjct: 314 EKPPEEDKEEEEEKKAPTPQEKKRRKDSSE----ESDSSEESDIDSEASSALFMAKKKTP 369

Query: 357 ATNKLSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVS------RKSPLAEEGRLNCSTSP 410
              +  PSG  +   S   +P     S+    R   S      R S +    RL   T P
Sbjct: 370 PKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGP 429

Query: 411 EIFRKCMDYSSDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQT 460
           +           S  T   S  V+    A      + P T+  L +K QT
Sbjct: 430 QSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQT 479


>gi|5453567 craniofacial development protein 1 [Homo sapiens]
          Length = 299

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 22  IQEAEDVDELEDEEEGAETRGA-----GDPARYLSPGWGSASEEEPSRGHSGTTASGGEN 76
           + E    DE++ EE+  +T+G        PAR    G  S  EEE    +S +  S  E 
Sbjct: 30  VNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSESEGSSSEE 89

Query: 77  EREDLEQEWKPPDEELIKKLVDQI 100
           E +  EQE     E+  KK  D++
Sbjct: 90  EDDAAEQEKGIGSEDARKKKEDEL 113


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,953,120
Number of Sequences: 37866
Number of extensions: 1146185
Number of successful extensions: 4742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 167
Number of HSP's that attempted gapping in prelim test: 4469
Number of HSP's gapped (non-prelim): 376
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.