BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|36949366 mutS homolog 4 [Homo sapiens] (936 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|36949366 mutS homolog 4 [Homo sapiens] 1841 0.0 gi|68303635 mutS homolog 3 [Homo sapiens] 245 2e-64 gi|4557761 mutS homolog 2 [Homo sapiens] 207 3e-53 gi|4505253 mutS homolog 5 isoform c [Homo sapiens] 143 9e-34 gi|26638662 mutS homolog 5 isoform a [Homo sapiens] 143 9e-34 gi|26638666 mutS homolog 5 isoform c [Homo sapiens] 143 9e-34 gi|26638664 mutS homolog 5 isoform b [Homo sapiens] 139 2e-32 gi|4504191 mutS homolog 6 [Homo sapiens] 129 1e-29 gi|58530845 zyxin [Homo sapiens] 46 1e-04 gi|4508047 zyxin [Homo sapiens] 46 1e-04 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 43 0.001 gi|189011568 adenomatous polyposis coli [Homo sapiens] 41 0.005 gi|189011566 adenomatous polyposis coli [Homo sapiens] 41 0.005 gi|53759122 adenomatous polyposis coli [Homo sapiens] 41 0.005 gi|24430146 nucleoporin 153kDa [Homo sapiens] 41 0.005 gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 40 0.013 gi|91982772 mucin 17 [Homo sapiens] 39 0.030 gi|239753437 PREDICTED: hypothetical protein [Homo sapiens] 38 0.050 gi|239748002 PREDICTED: hypothetical protein [Homo sapiens] 38 0.050 gi|239741900 PREDICTED: hypothetical protein XP_002342343 [Homo ... 38 0.050 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 37 0.066 gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens] 37 0.086 gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens] 37 0.086 gi|189491742 ataxin 7 isoform b [Homo sapiens] 37 0.11 gi|4506797 ataxin 7 isoform a [Homo sapiens] 37 0.11 gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 37 0.11 gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 37 0.11 gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 37 0.11 gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 37 0.11 gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 36 0.15 >gi|36949366 mutS homolog 4 [Homo sapiens] Length = 936 Score = 1841 bits (4769), Expect = 0.0 Identities = 936/936 (100%), Positives = 936/936 (100%) Query: 1 MLRPEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAA 60 MLRPEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAA Sbjct: 1 MLRPEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAA 60 Query: 61 GDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT 120 GDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT Sbjct: 61 GDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT 120 Query: 121 PLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKN 180 PLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKN Sbjct: 121 PLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKN 180 Query: 181 PQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTI 240 PQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTI Sbjct: 181 PQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTI 240 Query: 241 QRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLK 300 QRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLK Sbjct: 241 QRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLK 300 Query: 301 ICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLV 360 ICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLV Sbjct: 301 ICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLV 360 Query: 361 DIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITN 420 DIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITN Sbjct: 361 DIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITN 420 Query: 421 LIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCL 480 LIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCL Sbjct: 421 LIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCL 480 Query: 481 NMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQ 540 NMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQ Sbjct: 481 NMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQ 540 Query: 541 MTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLL 600 MTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLL Sbjct: 541 MTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLL 600 Query: 601 SEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAE 660 SEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAE Sbjct: 601 SEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAE 660 Query: 661 KPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIF 720 KPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIF Sbjct: 661 KPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIF 720 Query: 721 TRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEY 780 TRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEY Sbjct: 721 TRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEY 780 Query: 781 LLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEE 840 LLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEE Sbjct: 781 LLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEE 840 Query: 841 KNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTAR 900 KNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTAR Sbjct: 841 KNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTAR 900 Query: 901 NSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE 936 NSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE Sbjct: 901 NSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE 936 >gi|68303635 mutS homolog 3 [Homo sapiens] Length = 1137 Score = 245 bits (625), Expect = 2e-64 Identities = 195/732 (26%), Positives = 365/732 (49%), Gaps = 74/732 (10%) Query: 171 IGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLF----T 226 IG+ + +++ F D+ + +++ T++ L P+E+++ + A+ T+ T Sbjct: 388 IGIVGVQPATGEVVFDSFQDSASRSELETRMSSLQPVELLLPS---ALSEQTEALIHRAT 444 Query: 227 LITENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEFSTV--------LMEVQSKYYCLAA 278 ++ + + YF + + + + + + ++ ++ C + Sbjct: 445 SVSVQDDRIRVERMDNIYFEYSHAFQAVTEFYAKDTVDIKGSQIISGIVNLEKPVIC--S 502 Query: 279 VAALLKYV-EF-IQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLF 336 +AA++KY+ EF ++ + P++ K + I+ ++ +NLE+L N D + +L Sbjct: 503 LAAIIKYLKEFNLEKMLSKPENFKQ-LSSKMEFMTINGTTLRNLEILQNQTDMKTKGSLL 561 Query: 337 GVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFG-LQSVISRFLDT 395 VL++TKT G R+L+ + +PL+ + IN RLD V E+L E FG +++ + + D Sbjct: 562 WVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSEVLHSESSVFGQIENHLRKLPDI 621 Query: 396 EQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLED 455 E+ L + K+ + + L +LK + + P + + LLR Sbjct: 622 ERGLCSIYH--KKCSTQEFFLIVKTLYHLKSEFQAIIPA--VNSHIQSDLLRT------- 670 Query: 456 KRFGIILEKIKTVINDDARYMKGCLNMRTQKC---YAVRSNINEFLDIARRT--YTEIVD 510 +ILE I +++ Y+K LN + K + ++++F I +R ++D Sbjct: 671 ----VILE-IPELLSPVEHYLK-ILNEQAAKVGDKTELFKDLSDFPLIKKRKDEIQGVID 724 Query: 511 DIAGMISQLGEKYSLPLRTSFS-SARGFFIQMTTDCIALPSDQLPSEFIKISKVKNSYSF 569 +I + ++ + P + S + F I++ ++ +P++++K+ K F Sbjct: 725 EIRMHLQEIRKILKNPSAQYVTVSGQEFMIEIKNSAVSC----IPTDWVKVGSTKAVSRF 780 Query: 570 TSADLIKMNERCQESLREIYHMTYMIVCK-----LLSEIYEHIHCLYKLSDTVSMLDMLL 624 S +++ N R LRE ++ C L + EH H L K ++ +D + Sbjct: 781 HSPFIVE-NYRHLNQLRE----QLVLDCSAEWLDFLEKFSEHYHSLCKAVHHLATVDCIF 835 Query: 625 SFAHACTLSDYVRPEFTDT--LAIKQGWHPILEKISAEKP--IANNTYVTEGSN-FLIIT 679 S A DY RP + + IK G HP+++ + E+ + NNT ++E S +IIT Sbjct: 836 SLAKVAKQGDYCRPTVQEERKIVIKNGRHPVIDVLLGEQDQYVPNNTDLSEDSERVMIIT 895 Query: 680 GPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKE 739 GPNM GKS+Y+KQ+AL IMAQIGSYVPAE ++ I IFTR+ D+I STFM+E Sbjct: 896 GPNMGGKSSYIKQVALITIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGRSTFMEE 955 Query: 740 MKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLL-SLKAFTLFATHFLELC 798 + + A I+ A +SL+++DELGRGT+T +GI I YA EY + +K+ TLF TH+ +C Sbjct: 956 LTDTAEIIRKATSQSLVILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPVC 1015 Query: 799 HIDALYPN-VENMHFEVQHVKNTSR--------NKEAILYTYKLSKGLTEEKNYGLKAAE 849 ++ Y + V N H ++ S+ + + + Y++++G+ ++YGL A+ Sbjct: 1016 ELEKNYSHQVGNYHMGFLVSEDESKLDPGAAEQVPDFVTFLYQITRGIA-ARSYGLNVAK 1074 Query: 850 VSSLPPSIVLDA 861 ++ +P I+ A Sbjct: 1075 LADVPGEILKKA 1086 >gi|4557761 mutS homolog 2 [Homo sapiens] Length = 934 Score = 207 bits (528), Expect = 3e-53 Identities = 194/716 (27%), Positives = 337/716 (47%), Gaps = 51/716 (7%) Query: 170 EIGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIM--SNTACAVGNSTKLFT- 226 ++G+ +D ++ L +F DN ++ + L + P E ++ TA +G ++ Sbjct: 160 QVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQR 219 Query: 227 ---LITENFKNVNFTT--IQRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAA 281 LITE K +F+T I + KG + EQ+ S VL E++++ +++++A Sbjct: 220 GGILITER-KKADFSTKDIYQDLNRLLKGKKG-EQMN----SAVLPEMENQV-AVSSLSA 272 Query: 282 LLKYVEFIQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINN-QDYRNNHTLFGVLN 340 ++K++E + + + F S Q +D ++ + L L + +D + +L +LN Sbjct: 273 VIKFLELLSDDSNFGQFELTTFDFS-QYMKLDIAAVRALNLFQGSVEDTTGSQSLAALLN 331 Query: 341 YTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQS-VISRFLDTEQLL 399 KTP G R + I +PL+D I RL+ V+ ++D EL LQ ++ RF D +L Sbjct: 332 KCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLA 391 Query: 400 SVLVQIPKQDTVNAAESKITNLIY--LKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKR 457 K+ AA + +Y + ++ L+ LL + L D R Sbjct: 392 -------KKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLR 444 Query: 458 --FGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGM 515 F E I+T ++ D N + N++E +I ++ + Sbjct: 445 SDFSKFQEMIETTLDMDQ-----VENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISA 499 Query: 516 ISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLI 575 LG ++ S+ G++ ++T C + F + KN FT++ L Sbjct: 500 ARDLGLDPGKQIKLDSSAQFGYYFRVT--CKEEKVLRNNKNFSTVDIQKNGVKFTNSKLT 557 Query: 576 KMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSD- 634 +NE ++ E IV ++++ ++ + L+D ++ LD ++SFAH + Sbjct: 558 SLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPV 617 Query: 635 -YVRPEFTDT----LAIKQGWHPILEKISAEKPIANNTYVTEGSN-FLIITGPNMSGKST 688 YVRP + + +K H +E I N+ Y + F IITGPNM GKST Sbjct: 618 PYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKST 677 Query: 689 YLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKEMKEIAYILH 748 Y++Q + +MAQIG +VP E + I I R+ D STFM EM E A IL Sbjct: 678 YIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILR 737 Query: 749 NANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS-LKAFTLFATHFLELCHIDALYPNV 807 +A SLI+IDELGRGT+T +G G+ +A+ EY+ + + AF +FATHF EL + P V Sbjct: 738 SATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTV 797 Query: 808 ENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKE 863 N+H +E + Y++ KG+ ++ ++G+ AE+++ P ++ AK+ Sbjct: 798 NNLHV------TALTTEETLTMLYQVKKGVCDQ-SFGIHVAELANFPKHVIECAKQ 846 >gi|4505253 mutS homolog 5 isoform c [Homo sapiens] Length = 834 Score = 143 bits (360), Expect = 9e-34 Identities = 144/558 (25%), Positives = 260/558 (46%), Gaps = 55/558 (9%) Query: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFL 393 +LFG+LN G + LR P D+ ++ RLD +Q L + L + ++ R L Sbjct: 253 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNL--DMAQMLHRLL 310 Query: 394 DTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC--NTPLLRAYYG 451 + + ++++ K + +K+++ L T+ L+ A ++ + L R Sbjct: 311 GHIKNVPLILKRMK-----LSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQ 365 Query: 452 SLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDD 511 D L I ++I + +G L + + V NI+ +D +R Sbjct: 366 EFSDD-----LHHIASLIGKVVDF-EGSL---AENRFTVLPNIDPEIDEKKRRLM----G 412 Query: 512 IAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPS------------EFIK 559 + ++++ K L + S +I + +++P +LPS +F+ Sbjct: 413 LPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIP--RLPSMVEASDFEINGLDFMF 470 Query: 560 ISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSM 619 +S+ K Y SA +++ + EI +++ +L ++ L ++ D S Sbjct: 471 LSEEKLHYR--SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASR 528 Query: 620 LDMLLSFAHACTLSDYVRPEFTDTLA---IKQGWHPILEKISAEKPIANNTYVT-EGSNF 675 LD+LL+ A A Y RP ++ + I+ G HP++E + A + N+T + Sbjct: 529 LDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLME-LCARTFVPNSTECGGDKGRV 587 Query: 676 LIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSST 735 +ITGPN SGKS YLKQ+ L MA +GS+VPAE + IFTRI + + I ST Sbjct: 588 KVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLST 647 Query: 736 FMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS---LKAFTLFAT 792 FM ++ ++A ++NA +SL+LIDE G+GTNT +G+ + AV + L+ AT Sbjct: 648 FMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVAT 707 Query: 793 HFLELCHIDAL--YPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEV 850 +FL L + L P V+ + E T + +++ Y++ +G+ + + AA+ Sbjct: 708 NFLSLVQLQLLPQGPLVQYLTME------TCEDGNDLVFFYQVCEGVAKASHASHTAAQ- 760 Query: 851 SSLPPSIVLDAKEITTQI 868 + LP +V KE++ I Sbjct: 761 AGLPDKLVARGKEVSDLI 778 >gi|26638662 mutS homolog 5 isoform a [Homo sapiens] Length = 851 Score = 143 bits (360), Expect = 9e-34 Identities = 144/558 (25%), Positives = 260/558 (46%), Gaps = 55/558 (9%) Query: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFL 393 +LFG+LN G + LR P D+ ++ RLD +Q L + L + ++ R L Sbjct: 270 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNL--DMAQMLHRLL 327 Query: 394 DTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC--NTPLLRAYYG 451 + + ++++ K + +K+++ L T+ L+ A ++ + L R Sbjct: 328 GHIKNVPLILKRMK-----LSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQ 382 Query: 452 SLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDD 511 D L I ++I + +G L + + V NI+ +D +R Sbjct: 383 EFSDD-----LHHIASLIGKVVDF-EGSL---AENRFTVLPNIDPEIDEKKRRLM----G 429 Query: 512 IAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPS------------EFIK 559 + ++++ K L + S +I + +++P +LPS +F+ Sbjct: 430 LPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIP--RLPSMVEASDFEINGLDFMF 487 Query: 560 ISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSM 619 +S+ K Y SA +++ + EI +++ +L ++ L ++ D S Sbjct: 488 LSEEKLHYR--SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASR 545 Query: 620 LDMLLSFAHACTLSDYVRPEFTDTLA---IKQGWHPILEKISAEKPIANNTYVT-EGSNF 675 LD+LL+ A A Y RP ++ + I+ G HP++E + A + N+T + Sbjct: 546 LDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLME-LCARTFVPNSTECGGDKGRV 604 Query: 676 LIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSST 735 +ITGPN SGKS YLKQ+ L MA +GS+VPAE + IFTRI + + I ST Sbjct: 605 KVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLST 664 Query: 736 FMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS---LKAFTLFAT 792 FM ++ ++A ++NA +SL+LIDE G+GTNT +G+ + AV + L+ AT Sbjct: 665 FMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVAT 724 Query: 793 HFLELCHIDAL--YPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEV 850 +FL L + L P V+ + E T + +++ Y++ +G+ + + AA+ Sbjct: 725 NFLSLVQLQLLPQGPLVQYLTME------TCEDGNDLVFFYQVCEGVAKASHASHTAAQ- 777 Query: 851 SSLPPSIVLDAKEITTQI 868 + LP +V KE++ I Sbjct: 778 AGLPDKLVARGKEVSDLI 795 >gi|26638666 mutS homolog 5 isoform c [Homo sapiens] Length = 834 Score = 143 bits (360), Expect = 9e-34 Identities = 144/558 (25%), Positives = 260/558 (46%), Gaps = 55/558 (9%) Query: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFL 393 +LFG+LN G + LR P D+ ++ RLD +Q L + L + ++ R L Sbjct: 253 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNL--DMAQMLHRLL 310 Query: 394 DTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC--NTPLLRAYYG 451 + + ++++ K + +K+++ L T+ L+ A ++ + L R Sbjct: 311 GHIKNVPLILKRMK-----LSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQ 365 Query: 452 SLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDD 511 D L I ++I + +G L + + V NI+ +D +R Sbjct: 366 EFSDD-----LHHIASLIGKVVDF-EGSL---AENRFTVLPNIDPEIDEKKRRLM----G 412 Query: 512 IAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPS------------EFIK 559 + ++++ K L + S +I + +++P +LPS +F+ Sbjct: 413 LPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIP--RLPSMVEASDFEINGLDFMF 470 Query: 560 ISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSM 619 +S+ K Y SA +++ + EI +++ +L ++ L ++ D S Sbjct: 471 LSEEKLHYR--SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASR 528 Query: 620 LDMLLSFAHACTLSDYVRPEFTDTLA---IKQGWHPILEKISAEKPIANNTYVT-EGSNF 675 LD+LL+ A A Y RP ++ + I+ G HP++E + A + N+T + Sbjct: 529 LDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLME-LCARTFVPNSTECGGDKGRV 587 Query: 676 LIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSST 735 +ITGPN SGKS YLKQ+ L MA +GS+VPAE + IFTRI + + I ST Sbjct: 588 KVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLST 647 Query: 736 FMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS---LKAFTLFAT 792 FM ++ ++A ++NA +SL+LIDE G+GTNT +G+ + AV + L+ AT Sbjct: 648 FMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVAT 707 Query: 793 HFLELCHIDAL--YPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEV 850 +FL L + L P V+ + E T + +++ Y++ +G+ + + AA+ Sbjct: 708 NFLSLVQLQLLPQGPLVQYLTME------TCEDGNDLVFFYQVCEGVAKASHASHTAAQ- 760 Query: 851 SSLPPSIVLDAKEITTQI 868 + LP +V KE++ I Sbjct: 761 AGLPDKLVARGKEVSDLI 778 >gi|26638664 mutS homolog 5 isoform b [Homo sapiens] Length = 835 Score = 139 bits (349), Expect = 2e-32 Identities = 144/559 (25%), Positives = 261/559 (46%), Gaps = 56/559 (10%) Query: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFL 393 +LFG+LN G + LR P D+ ++ RLD +Q L + L + ++ R L Sbjct: 253 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNL--DMAQMLHRLL 310 Query: 394 DTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC--NTPLLRAYYG 451 + + ++++ K + +K+++ L T+ L+ A ++ + L R Sbjct: 311 GHIKNVPLILKRMK-----LSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQ 365 Query: 452 SLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDD 511 D L I ++I + +G L + + V NI+ +D +R Sbjct: 366 EFSDD-----LHHIASLIGKVVDF-EGSL---AENRFTVLPNIDPEIDEKKRRLM----G 412 Query: 512 IAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPS------------EFIK 559 + ++++ K L + S +I + +++P +LPS +F+ Sbjct: 413 LPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIP--RLPSMVEASDFEINGLDFMF 470 Query: 560 ISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSM 619 +S+ K Y SA +++ + EI +++ +L ++ L ++ D S Sbjct: 471 LSEEKLHYR--SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASR 528 Query: 620 LDMLLSFAHACTLSDYVRPEFTDTLA---IKQGWHPILEKISAEKPIANNTYVT-EGSNF 675 LD+LL+ A A Y RP ++ + I+ G HP++E + A + N+T + Sbjct: 529 LDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLME-LCARTFVPNSTECGGDKGRV 587 Query: 676 LIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSST 735 +ITGPN SGKS YLKQ+ L MA +GS+VPAE + IFTRI + + I ST Sbjct: 588 KVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLST 647 Query: 736 FMKEM-KEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS---LKAFTLFA 791 FM ++ +++A ++NA +SL+LIDE G+GTNT +G+ + AV + L+ A Sbjct: 648 FMIDLNQQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVA 707 Query: 792 THFLELCHIDAL--YPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAE 849 T+FL L + L P V+ + E T + +++ Y++ +G+ + + AA+ Sbjct: 708 TNFLSLVQLQLLPQGPLVQYLTME------TCEDGNDLVFFYQVCEGVAKASHASHTAAQ 761 Query: 850 VSSLPPSIVLDAKEITTQI 868 + LP +V KE++ I Sbjct: 762 -AGLPDKLVARGKEVSDLI 779 >gi|4504191 mutS homolog 6 [Homo sapiens] Length = 1360 Score = 129 bits (324), Expect = 1e-29 Identities = 106/371 (28%), Positives = 165/371 (44%), Gaps = 51/371 (13%) Query: 572 ADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACT 631 A+LI ER SL++ + K + + C +++LD+LL A+ Sbjct: 1016 ANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVEC-------IAVLDVLLCLANYSR 1068 Query: 632 LSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSNFL--------------- 676 D P + + + P LE + P T+ G +F+ Sbjct: 1069 GGD--GPMCRPVILLPEDTPPFLELKGSRHPCITKTFF--GDDFIPNDILIGCEEEEQEN 1124 Query: 677 ------IITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIE 730 ++TGPNM GKST ++Q L +MAQ+G YVPAE ++FTR+ D I Sbjct: 1125 GKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIM 1184 Query: 731 TNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLL-SLKAFTL 789 + STF E+ E A IL +A SL+L+DELGRGT T +G I AV + L ++K TL Sbjct: 1185 SGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTL 1244 Query: 790 FATHFLELCHIDALYPNVENMHFEVQHVKNTSR--NKEAILYTYKLSKGLTEEKNYGLKA 847 F+TH+ L + V H V+N ++E I + YK KG K+YG A Sbjct: 1245 FSTHYHSLVEDYSQNVAVRLGHMACM-VENECEDPSQETITFLYKFIKGAC-PKSYGFNA 1302 Query: 848 AEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTARNSQLDPD 907 A +++LP + I + R E E+ L + + S +D + Sbjct: 1303 ARLANLPEEV--------------IQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAE 1348 Query: 908 SLRIYLSNLKK 918 ++ L+ +K+ Sbjct: 1349 AVHKLLTLIKE 1359 Score = 49.3 bits (116), Expect = 2e-05 Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 1/125 (0%) Query: 276 LAAVAALLKYVEFIQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTL 335 L ++A +Y+ ++V +S I F + Q ++D+ + NLE+ +N + TL Sbjct: 700 LLSMANFEEYIPLDSDTVSTTRSGAI-FTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTL 758 Query: 336 FGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFLDT 395 ++ TP G R L+ + PL + IN RLD +++L+ + + ++ + D Sbjct: 759 LERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDL 818 Query: 396 EQLLS 400 E+LLS Sbjct: 819 ERLLS 823 >gi|58530845 zyxin [Homo sapiens] Length = 572 Score = 46.2 bits (108), Expect = 1e-04 Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 21/135 (15%) Query: 3 RPEISSTSPSAPAVSPSSGE----TRSPQGPRYNFGLQETPQSRPSVQV-VSASTCPGTS 57 +P T+P P SPSS + +P + F +Q PQ +P VQ+ V + T P + Sbjct: 188 KPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSL 247 Query: 58 GAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTN---- 113 R +SS P PAP P + VAS F+ GA S N Sbjct: 248 ANTQPRGPPASS-PAPAPKFSPVTPKF---------TPVASKFSPGAPGGSGSQPNQKLG 297 Query: 114 YPQTLKTPLSTGNPQ 128 +P+ L TG+PQ Sbjct: 298 HPEALSA--GTGSPQ 310 >gi|4508047 zyxin [Homo sapiens] Length = 572 Score = 46.2 bits (108), Expect = 1e-04 Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 21/135 (15%) Query: 3 RPEISSTSPSAPAVSPSSGE----TRSPQGPRYNFGLQETPQSRPSVQV-VSASTCPGTS 57 +P T+P P SPSS + +P + F +Q PQ +P VQ+ V + T P + Sbjct: 188 KPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSL 247 Query: 58 GAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTN---- 113 R +SS P PAP P + VAS F+ GA S N Sbjct: 248 ANTQPRGPPASS-PAPAPKFSPVTPKF---------TPVASKFSPGAPGGSGSQPNQKLG 297 Query: 114 YPQTLKTPLSTGNPQ 128 +P+ L TG+PQ Sbjct: 298 HPEALSA--GTGSPQ 310 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 43.1 bits (100), Expect = 0.001 Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 10/162 (6%) Query: 4 PEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQV---------VSASTCP 54 P S+ P AP + G+ GP F P+S Q S+S+ Sbjct: 2506 PAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSS 2565 Query: 55 GTSGAAGDRSSSSSSLPCPAPNSRPAQGSY-FGNKRAYAENTVASNFTFGASSSSARDTN 113 G+S ++ SSS S + G G + A ++ A++ +SSSS+ ++ Sbjct: 2566 GSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSS 2625 Query: 114 YPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155 + + S+ + S S + S+SSSS+ S+ S S Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2667 Score = 33.1 bits (74), Expect = 1.2 Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 9/153 (5%) Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66 SS+S S+ + S + GE + G S S + S ++ +S ++ SSS Sbjct: 2569 SSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSS 2628 Query: 67 SSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT-----P 121 SSS + +S + S + + + ++ +S+ + +SSSS+ T+ + + P Sbjct: 2629 SSS-SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687 Query: 122 LSTGNPQRSGYKSWTPQVGYSASSSSAISAHSP 154 T P ++ P + + SAHSP Sbjct: 2688 APTAGPSA---QAALPTKATKQAGKARPSAHSP 2717 >gi|189011568 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 41.2 bits (95), Expect = 0.005 Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 13/165 (7%) Query: 2 LRPEISSTSP---------SAPAVSPSSGETR--SPQGPRYNFGLQETPQSRPSVQVVSA 50 +R SSTSP + + SPS G+T SP+G + + + +P +R + Q+ + Sbjct: 2236 VRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGS 2295 Query: 51 STCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSAR 110 S P SG+ S + P P P + S + + S +S S+A Sbjct: 2296 SKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAS 2355 Query: 111 DTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155 + + S G ++ ++ T Q G S ++SS + S S Sbjct: 2356 TKSSGSGKMSYTSPG--RQMSQQNLTKQTGLSKNASSIPRSESAS 2398 >gi|189011566 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 41.2 bits (95), Expect = 0.005 Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 13/165 (7%) Query: 2 LRPEISSTSP---------SAPAVSPSSGETR--SPQGPRYNFGLQETPQSRPSVQVVSA 50 +R SSTSP + + SPS G+T SP+G + + + +P +R + Q+ + Sbjct: 2236 VRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGS 2295 Query: 51 STCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSAR 110 S P SG+ S + P P P + S + + S +S S+A Sbjct: 2296 SKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAS 2355 Query: 111 DTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155 + + S G ++ ++ T Q G S ++SS + S S Sbjct: 2356 TKSSGSGKMSYTSPG--RQMSQQNLTKQTGLSKNASSIPRSESAS 2398 >gi|53759122 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 41.2 bits (95), Expect = 0.005 Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 13/165 (7%) Query: 2 LRPEISSTSP---------SAPAVSPSSGETR--SPQGPRYNFGLQETPQSRPSVQVVSA 50 +R SSTSP + + SPS G+T SP+G + + + +P +R + Q+ + Sbjct: 2236 VRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGS 2295 Query: 51 STCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSAR 110 S P SG+ S + P P P + S + + S +S S+A Sbjct: 2296 SKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAS 2355 Query: 111 DTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155 + + S G ++ ++ T Q G S ++SS + S S Sbjct: 2356 TKSSGSGKMSYTSPG--RQMSQQNLTKQTGLSKNASSIPRSESAS 2398 >gi|24430146 nucleoporin 153kDa [Homo sapiens] Length = 1475 Score = 41.2 bits (95), Expect = 0.005 Identities = 36/142 (25%), Positives = 57/142 (40%), Gaps = 28/142 (19%) Query: 6 ISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSS 65 + T PSAP+ SP+ G ++P + Q P S+ +A G+ A + Sbjct: 1305 VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGT 1364 Query: 66 SSSSLPCPAPNSRPAQGSY-------------FGNKRA---YAENTVASNFTFGASSSSA 109 SSS P +P+Q ++ FG+ + N+ + FTFGA+SS Sbjct: 1365 VSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS-- 1422 Query: 110 RDTNYPQTLKTPLSTGNPQRSG 131 TP ++ P SG Sbjct: 1423 ----------TPAASAQPSGSG 1434 Score = 30.4 bits (67), Expect = 8.1 Identities = 36/114 (31%), Positives = 50/114 (43%), Gaps = 22/114 (19%) Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQ--VVSASTCPGTSGAAGDRS 64 SS+S S PA S G FG T S P V V S+ P +S A G+ + Sbjct: 1196 SSSSSSTPATSAGGGI----------FG-SSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244 Query: 65 SSSSSLPCP-APNSRPAQGSYFGNK--------RAYAENTVASNFTFGASSSSA 109 SS+S + +S+ A S G A + NT S F FGA+++S+ Sbjct: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSS 1298 >gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] Length = 1970 Score = 39.7 bits (91), Expect = 0.013 Identities = 47/165 (28%), Positives = 65/165 (39%), Gaps = 15/165 (9%) Query: 4 PEISSTSPSAPAVSPSSGETR---SPQGPRYNFGLQETPQSRPSVQVVSAS---TCPGTS 57 P S TSPS SPS T SP P Y+ + PS S S T P S Sbjct: 1634 PNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1693 Query: 58 GAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQT 117 + S +S S +P+ P SY +Y+ + + + T + S S NY T Sbjct: 1694 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT--SPSYSPTSPNYSPT 1751 Query: 118 LK--TPLSTG-NPQRSGYK----SWTPQVGYSASSSSAISAHSPS 155 TP S +P Y ++TP + +S + S SPS Sbjct: 1752 SPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPS 1796 Score = 38.5 bits (88), Expect = 0.030 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 5/151 (3%) Query: 8 STSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVS---ASTCPGTSGAAGDRS 64 S SP++PA P S +PQ P Y+ + PS S + T P S + S Sbjct: 1592 SYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYS 1651 Query: 65 SSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLST 124 +S S +P+ P SY +Y+ + + + T + S S +Y T + T Sbjct: 1652 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT--SPSYSPTSPSYSPTSPSYSPT 1709 Query: 125 GNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155 S++P + +S + S SPS Sbjct: 1710 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1740 Score = 38.1 bits (87), Expect = 0.039 Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 13/162 (8%) Query: 4 PEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSAS---TCPGTSGAA 60 P+ S SP++P+ SP+S + SP P Y+ + PS S S T P S + Sbjct: 1610 PQSPSYSPTSPSYSPTS-PSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1668 Query: 61 GDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT 120 S +S S +P+ P SY +Y+ + + + T + S ++ + + Sbjct: 1669 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1728 Query: 121 PLSTG-NPQRSGYKSWTPQVGYSASS------SSAISAHSPS 155 P S +P Y +P YS +S S + S SPS Sbjct: 1729 PTSPSYSPTSPSYSPTSP--NYSPTSPNYTPTSPSYSPTSPS 1768 Score = 35.4 bits (80), Expect = 0.25 Identities = 42/165 (25%), Positives = 56/165 (33%), Gaps = 14/165 (8%) Query: 4 PEISSTSPSAPAVSPSSGETR---SPQGPRYNFGLQETPQSRPSVQVVSAS---TCPGTS 57 P S TSPS SPS T SP PRY S PS S S T P + Sbjct: 1781 PNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYT 1840 Query: 58 GAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQT 117 + S SS +P P Y Y+ + + T S ++ + Sbjct: 1841 PTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSP 1900 Query: 118 LKTPLS--------TGNPQRSGYKSWTPQVGYSASSSSAISAHSP 154 + TP S T +P Y +P ++ S S SP Sbjct: 1901 VYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSP 1945 Score = 32.0 bits (71), Expect = 2.8 Identities = 39/149 (26%), Positives = 56/149 (37%), Gaps = 8/149 (5%) Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66 S +P A SPS+ S P Y+ TP S P S+ P GA S Sbjct: 1537 SGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGS-PGSPGPSSPYIPSPGGAMSPSYSP 1595 Query: 67 SSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126 +S P P S G Y +Y+ + + + T + S S NY T + T Sbjct: 1596 TS--PAYEPRS---PGGYTPQSPSYSPTSPSYSPT--SPSYSPTSPNYSPTSPSYSPTSP 1648 Query: 127 PQRSGYKSWTPQVGYSASSSSAISAHSPS 155 S++P + +S + S SPS Sbjct: 1649 SYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1677 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 38.5 bits (88), Expect = 0.030 Identities = 43/164 (26%), Positives = 69/164 (42%), Gaps = 21/164 (12%) Query: 12 SAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSLP 71 S P +PS G T P + + TP + ++S T P S S+ +SS P Sbjct: 3211 SIPTSTPSEGMT-----PLTSVPVSNTPVASSEASILS--TTPVDSNTPLTTSTEASSSP 3263 Query: 72 CPA-----PNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126 A P S P++GS + TVAS+ T S++ A DT+ P T + S+ Sbjct: 3264 PTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPA-DTSTPVTTYSQASSSP 3322 Query: 127 PQRSG--------YKSWTPQVGYSASSSSAISAHSPSVIVAVVE 162 P G + TP S S++ +S+ + ++ V+ Sbjct: 3323 PIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVD 3366 Score = 34.7 bits (78), Expect = 0.43 Identities = 39/146 (26%), Positives = 59/146 (40%), Gaps = 6/146 (4%) Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66 +S S P +PS G T P + + S S V ST TS A +SS Sbjct: 3148 TSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEA---TSS 3204 Query: 67 SSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126 +++ P S P++G + VAS+ S++ D+N P T T S+ Sbjct: 3205 TTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEA-SILSTTPVDSNTPLTTSTEASSSP 3263 Query: 127 PQRSG--YKSWTPQVGYSASSSSAIS 150 P G + TP G + +S +S Sbjct: 3264 PTAEGTSMPTSTPSEGSTPLTSMPVS 3289 Score = 33.1 bits (74), Expect = 1.2 Identities = 46/216 (21%), Positives = 86/216 (39%), Gaps = 36/216 (16%) Query: 5 EISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRS 64 E +S+ +A +S + + P + + TP + + ST P S + S Sbjct: 1432 EATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTL--STTPVDSNSPVVTS 1489 Query: 65 SSSSSLPCPAPN-----SRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLK 119 ++ SS P PA S P++GS + TVAS+ S++ P Sbjct: 1490 TAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTT-------PAVTS 1542 Query: 120 TPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLK 179 TP++T YS +SSS +A S+ + + G + S+ + Sbjct: 1543 TPVTT----------------YSQASSSPTTADGTSMQTST-----YSEGSTPLTSLPV- 1580 Query: 180 NPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTA 215 + +++S A+ + + +K ++ + E S TA Sbjct: 1581 STMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTA 1616 Score = 32.0 bits (71), Expect = 2.8 Identities = 45/192 (23%), Positives = 75/192 (39%), Gaps = 11/192 (5%) Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66 SST+ +++ S+ SP + + TP + P +S T P S + S+ Sbjct: 1612 SSTTAEGSSMTISTPSEGSPL--LTSIPVSTTPVASPEASTLS--TTPVDSNSPVITSTE 1667 Query: 67 SSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126 SS P PA + +Y + TV + T ASS+ + + P TP++T Sbjct: 1668 VSSSPTPAEGTSMPTSTYTEGRTPLTSITVRT--TPVASSAISTLSTTPVDNSTPVTTST 1725 Query: 127 PQRSGYKSWTPQVGYSASSSSAISAHSP--SVIVAVVEGRGLARGEIGMASIDLKNPQII 184 RS S T G S +S+ +P S+ V+ + ID P Sbjct: 1726 EARS---SPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTT 1782 Query: 185 LSQFADNTTYAK 196 ++ + T A+ Sbjct: 1783 STEATSSPTTAE 1794 Score = 31.2 bits (69), Expect = 4.7 Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 15/151 (9%) Query: 7 SSTSP---SAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63 SST+P S P +PS G T P N + + + S + + ST P S Sbjct: 551 SSTTPEGTSIPTSTPSEGST-----PLTN--MPVSTRLVVSSEASTTSTTPADSNTFVTT 603 Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLS 123 SS +SS A + +Y ++R +++ + T ASS ++ + P TP++ Sbjct: 604 SSEASSSSTTAEGTSMPTSTY--SERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT 661 Query: 124 TGNPQRSGYKSWTPQVGYSASSSSAISAHSP 154 T S S T G S +S+ +P Sbjct: 662 TSTEATS---SSTTAEGTSMPTSTYTEGSTP 689 >gi|239753437 PREDICTED: hypothetical protein [Homo sapiens] Length = 157 Score = 37.7 bits (86), Expect = 0.050 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 28/135 (20%) Query: 16 VSPSSGETRSPQGPRYNF-------GLQETPQSRPSV---QVVSASTCPGTSGAAGDRSS 65 ++ G+++ P GP +F G +P P++ ++ S G +GAA R++ Sbjct: 3 INGKKGQSQCPGGPGASFTWALSLRGTALSPGELPALWHHHLLVQSQDRGRAGAA--RTT 60 Query: 66 SSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTG 125 S SLP P SRPA G+K+ T+ +S + T + +K PL+ Sbjct: 61 KSESLPAPPATSRPAA----GDKKPLQGQTL-------RRASGLQATGRAEEVKPPLA-- 107 Query: 126 NPQRSGYKSWTPQVG 140 G+ W PQ G Sbjct: 108 ---HQGHAPWEPQNG 119 >gi|239748002 PREDICTED: hypothetical protein [Homo sapiens] Length = 157 Score = 37.7 bits (86), Expect = 0.050 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 28/135 (20%) Query: 16 VSPSSGETRSPQGPRYNF-------GLQETPQSRPSV---QVVSASTCPGTSGAAGDRSS 65 ++ G+++ P GP +F G +P P++ ++ S G +GAA R++ Sbjct: 3 INGKKGQSQCPGGPGASFTWALSLRGTALSPGELPALWHHHLLVQSQDRGRAGAA--RTT 60 Query: 66 SSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTG 125 S SLP P SRPA G+K+ T+ +S + T + +K PL+ Sbjct: 61 KSESLPAPPATSRPAA----GDKKPLQGQTL-------RRASGLQATGRAEEVKPPLA-- 107 Query: 126 NPQRSGYKSWTPQVG 140 G+ W PQ G Sbjct: 108 ---HQGHAPWEPQNG 119 >gi|239741900 PREDICTED: hypothetical protein XP_002342343 [Homo sapiens] Length = 157 Score = 37.7 bits (86), Expect = 0.050 Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 28/135 (20%) Query: 16 VSPSSGETRSPQGPRYNF-------GLQETPQSRPSV---QVVSASTCPGTSGAAGDRSS 65 ++ G+++ P GP +F G +P P++ ++ S G +GAA R++ Sbjct: 3 INGKKGQSQCPGGPGASFTWALSLRGTALSPGELPALWHHHLLVQSQDRGRAGAA--RTT 60 Query: 66 SSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTG 125 S SLP P SRPA G+K+ T+ +S + T + +K PL+ Sbjct: 61 KSESLPAPPATSRPAA----GDKKPLQGQTL-------RRASGLQATGRAEEVKPPLA-- 107 Query: 126 NPQRSGYKSWTPQVG 140 G+ W PQ G Sbjct: 108 ---HQGHAPWEPQNG 119 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 37.4 bits (85), Expect = 0.066 Identities = 46/167 (27%), Positives = 60/167 (35%), Gaps = 23/167 (13%) Query: 9 TSPSAP--AVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66 TSP P A SG T P R TP S PS +++ P S G S Sbjct: 2381 TSPRVPLSAYERVSGRTSPPLLDRAR---SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ 2437 Query: 67 SSSLPC------PAPNS------------RPAQGSYFGNKRAYAENTVASNFTFGASSSS 108 S P P P++ P GS + A A T ++ G S Sbjct: 2438 SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP 2497 Query: 109 ARDTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155 A + + P STG Q S + P +SSSS+ S+ S S Sbjct: 2498 APGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544 Score = 37.4 bits (85), Expect = 0.066 Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 9/155 (5%) Query: 7 SSTSPSAPAVSPSSGETRS-------PQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGA 59 SS+S S+ + S SSG + S P P +P P V T Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAK 2602 Query: 60 AGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLK 119 RSSSSSS + +S + S + + + ++ +S+ + +S S A+ PQ L Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG--PQALP 2660 Query: 120 TPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSP 154 P S P +S +P+ + S ++SP Sbjct: 2661 KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSP 2695 Score = 36.6 bits (83), Expect = 0.11 Identities = 48/160 (30%), Positives = 67/160 (41%), Gaps = 13/160 (8%) Query: 4 PEISSTSPSAPAVSPSSGETR--SPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAG 61 PE SST P PA +P E SPQ P L + P + PS + P S Sbjct: 354 PERSSTGPEPPAPTPLLAERHGGSPQ-PLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL 412 Query: 62 DRSSSS-SSLPCPAPN--SRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTL 118 +SSSS SS P P P SR A S K A A + +SS ++++ ++ + Sbjct: 413 PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI----SSSPTSKNRSHGRAK 468 Query: 119 KTPLSTGNPQRSGYKSWTPQV---GYSASSSSAISAHSPS 155 + + P R +S +P G S S + HS S Sbjct: 469 RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRS 508 Score = 31.6 bits (70), Expect = 3.6 Identities = 42/162 (25%), Positives = 64/162 (39%), Gaps = 27/162 (16%) Query: 5 EISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRS 64 ++ S A PS+ P R + + S S S+S+ +S ++G S Sbjct: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS----SSSSSSSSSSSSGSSS 2560 Query: 65 SSS--SSLPC---------PAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTN 113 S S SSLP P+P P + G E T A +SSSS+ ++ Sbjct: 2561 SDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP---PEPTPAKRKRRSSSSSSSSSSS 2617 Query: 114 YPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155 S+ + S S + S+SSSS+ S+ SPS Sbjct: 2618 ---------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650 >gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens] Length = 922 Score = 37.0 bits (84), Expect = 0.086 Identities = 43/158 (27%), Positives = 66/158 (41%), Gaps = 22/158 (13%) Query: 4 PEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63 P S++P AP + T NF L P PSV + PG+ A Sbjct: 660 PPHGSSTPIAPVFTALPSFTSLTN----NFPLTGNPSLNPSVSL------PGSLIATSST 709 Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLS 123 +++S+SLP P+ + G + + S F + S+A + + T + PLS Sbjct: 710 AATSTSLPHPSSTAAVLSG--------LSASAPVSAAPFPLNLSTAVPSLFSVT-QGPLS 760 Query: 124 TGNPQRSGYK-SWTPQVGYSASSSSAISAHSPSVIVAV 160 + NP G+ S TP V + S + A PS + AV Sbjct: 761 SSNPSYPGFSVSNTPSVTPALPSFPGLQA--PSTVAAV 796 Score = 31.6 bits (70), Expect = 3.6 Identities = 37/166 (22%), Positives = 63/166 (37%), Gaps = 24/166 (14%) Query: 6 ISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCP------GTSGA 59 +++ P P S+ T P P + + P + S +T P G Sbjct: 287 LNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTTTPVPSIFSGLVSL 346 Query: 60 AGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQT-- 117 G ++ +++ P P P R S G+ A+A + ++SSSA T+ P + Sbjct: 347 PGPSATPTAATPTPGPTPR----STLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSAS 402 Query: 118 -------LKTPLSTGNPQRSGYKSWTPQV--GYSASSSSAISAHSP 154 L PL P G + TP + G + S + + +SP Sbjct: 403 LSSVFAGLPLPLP---PTSQGLSNPTPVIAGGSTPSVAGPLGVNSP 445 >gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens] Length = 944 Score = 37.0 bits (84), Expect = 0.086 Identities = 43/158 (27%), Positives = 66/158 (41%), Gaps = 22/158 (13%) Query: 4 PEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63 P S++P AP + T NF L P PSV + PG+ A Sbjct: 682 PPHGSSTPIAPVFTALPSFTSLTN----NFPLTGNPSLNPSVSL------PGSLIATSST 731 Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLS 123 +++S+SLP P+ + G + + S F + S+A + + T + PLS Sbjct: 732 AATSTSLPHPSSTAAVLSG--------LSASAPVSAAPFPLNLSTAVPSLFSVT-QGPLS 782 Query: 124 TGNPQRSGYK-SWTPQVGYSASSSSAISAHSPSVIVAV 160 + NP G+ S TP V + S + A PS + AV Sbjct: 783 SSNPSYPGFSVSNTPSVTPALPSFPGLQA--PSTVAAV 818 Score = 31.6 bits (70), Expect = 3.6 Identities = 37/166 (22%), Positives = 63/166 (37%), Gaps = 24/166 (14%) Query: 6 ISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCP------GTSGA 59 +++ P P S+ T P P + + P + S +T P G Sbjct: 309 LNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTTTPVPSIFSGLVSL 368 Query: 60 AGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQT-- 117 G ++ +++ P P P R S G+ A+A + ++SSSA T+ P + Sbjct: 369 PGPSATPTAATPTPGPTPR----STLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSAS 424 Query: 118 -------LKTPLSTGNPQRSGYKSWTPQV--GYSASSSSAISAHSP 154 L PL P G + TP + G + S + + +SP Sbjct: 425 LSSVFAGLPLPLP---PTSQGLSNPTPVIAGGSTPSVAGPLGVNSP 467 >gi|189491742 ataxin 7 isoform b [Homo sapiens] Length = 945 Score = 36.6 bits (83), Expect = 0.11 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 5/94 (5%) Query: 7 SSTSPSAPA---VSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63 SS+SPS P+ PSS +R PQ + + L+ S S +AS+ TSG +G + Sbjct: 649 SSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASS--STSGGSGKK 706 Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVA 97 +SS L + +S + S + ++ +N VA Sbjct: 707 RKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVA 740 >gi|4506797 ataxin 7 isoform a [Homo sapiens] Length = 892 Score = 36.6 bits (83), Expect = 0.11 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 5/94 (5%) Query: 7 SSTSPSAPA---VSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63 SS+SPS P+ PSS +R PQ + + L+ S S +AS+ TSG +G + Sbjct: 649 SSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASS--STSGGSGKK 706 Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVA 97 +SS L + +S + S + ++ +N VA Sbjct: 707 RKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVA 740 >gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] Length = 1083 Score = 36.6 bits (83), Expect = 0.11 Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 20/187 (10%) Query: 14 PAVSPSS-GETRSPQGPRYN--FGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSL 70 P SP + G T +PQ P Y Q PQ P A S S Sbjct: 840 PTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQ 899 Query: 71 PCPAPNS----RPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126 P P+P S P+ Y + + S + AS S + Y +P++ G Sbjct: 900 PSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPS-PVGY-----SPMTPGA 953 Query: 127 PQRSGYKSWTPQVGYSASSSS------AISAHSPSVIVAVVEGRGLARGEI-GMASIDLK 179 P GY TP G +SS + + VV G+ R GM S+ LK Sbjct: 954 PSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLK 1013 Query: 180 NPQIILS 186 + + ++S Sbjct: 1014 DSEKVVS 1020 >gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 36.6 bits (83), Expect = 0.11 Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 20/187 (10%) Query: 14 PAVSPSS-GETRSPQGPRYN--FGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSL 70 P SP + G T +PQ P Y Q PQ P A S S Sbjct: 844 PTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQ 903 Query: 71 PCPAPNS----RPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126 P P+P S P+ Y + + S + AS S + Y +P++ G Sbjct: 904 PSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPS-PVGY-----SPMTPGA 957 Query: 127 PQRSGYKSWTPQVGYSASSSS------AISAHSPSVIVAVVEGRGLARGEI-GMASIDLK 179 P GY TP G +SS + + VV G+ R GM S+ LK Sbjct: 958 PSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLK 1017 Query: 180 NPQIILS 186 + + ++S Sbjct: 1018 DSEKVVS 1024 >gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 36.6 bits (83), Expect = 0.11 Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 20/187 (10%) Query: 14 PAVSPSS-GETRSPQGPRYN--FGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSL 70 P SP + G T +PQ P Y Q PQ P A S S Sbjct: 844 PTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQ 903 Query: 71 PCPAPNS----RPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126 P P+P S P+ Y + + S + AS S + Y +P++ G Sbjct: 904 PSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPS-PVGY-----SPMTPGA 957 Query: 127 PQRSGYKSWTPQVGYSASSSS------AISAHSPSVIVAVVEGRGLARGEI-GMASIDLK 179 P GY TP G +SS + + VV G+ R GM S+ LK Sbjct: 958 PSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLK 1017 Query: 180 NPQIILS 186 + + ++S Sbjct: 1018 DSEKVVS 1024 >gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] Length = 1087 Score = 36.6 bits (83), Expect = 0.11 Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 20/187 (10%) Query: 14 PAVSPSS-GETRSPQGPRYN--FGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSL 70 P SP + G T +PQ P Y Q PQ P A S S Sbjct: 844 PTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQ 903 Query: 71 PCPAPNS----RPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126 P P+P S P+ Y + + S + AS S + Y +P++ G Sbjct: 904 PSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPS-PVGY-----SPMTPGA 957 Query: 127 PQRSGYKSWTPQVGYSASSSS------AISAHSPSVIVAVVEGRGLARGEI-GMASIDLK 179 P GY TP G +SS + + VV G+ R GM S+ LK Sbjct: 958 PSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLK 1017 Query: 180 NPQIILS 186 + + ++S Sbjct: 1018 DSEKVVS 1024 >gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] Length = 518 Score = 36.2 bits (82), Expect = 0.15 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Query: 4 PEISSTSPSAPAVSPS----SGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGA 59 PEIS T+PS P SP+ SGE + +G +T + P+ ++ GT A Sbjct: 337 PEISVTTPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPA 396 Query: 60 AGDRSSSSSSLPCPAPNSRPA 80 AG + ++ A +S PA Sbjct: 397 AGAQEPGETAASEAASSSLPA 417 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.131 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,462,672 Number of Sequences: 37866 Number of extensions: 1406705 Number of successful extensions: 6549 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 137 Number of HSP's that attempted gapping in prelim test: 6109 Number of HSP's gapped (non-prelim): 444 length of query: 936 length of database: 18,247,518 effective HSP length: 112 effective length of query: 824 effective length of database: 14,006,526 effective search space: 11541377424 effective search space used: 11541377424 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.