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Search of human proteins with 36949366
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|36949366 mutS homolog 4 [Homo sapiens]
(936 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|36949366 mutS homolog 4 [Homo sapiens] 1841 0.0
gi|68303635 mutS homolog 3 [Homo sapiens] 245 2e-64
gi|4557761 mutS homolog 2 [Homo sapiens] 207 3e-53
gi|4505253 mutS homolog 5 isoform c [Homo sapiens] 143 9e-34
gi|26638662 mutS homolog 5 isoform a [Homo sapiens] 143 9e-34
gi|26638666 mutS homolog 5 isoform c [Homo sapiens] 143 9e-34
gi|26638664 mutS homolog 5 isoform b [Homo sapiens] 139 2e-32
gi|4504191 mutS homolog 6 [Homo sapiens] 129 1e-29
gi|58530845 zyxin [Homo sapiens] 46 1e-04
gi|4508047 zyxin [Homo sapiens] 46 1e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 43 0.001
gi|189011568 adenomatous polyposis coli [Homo sapiens] 41 0.005
gi|189011566 adenomatous polyposis coli [Homo sapiens] 41 0.005
gi|53759122 adenomatous polyposis coli [Homo sapiens] 41 0.005
gi|24430146 nucleoporin 153kDa [Homo sapiens] 41 0.005
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 40 0.013
gi|91982772 mucin 17 [Homo sapiens] 39 0.030
gi|239753437 PREDICTED: hypothetical protein [Homo sapiens] 38 0.050
gi|239748002 PREDICTED: hypothetical protein [Homo sapiens] 38 0.050
gi|239741900 PREDICTED: hypothetical protein XP_002342343 [Homo ... 38 0.050
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 37 0.066
gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens] 37 0.086
gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens] 37 0.086
gi|189491742 ataxin 7 isoform b [Homo sapiens] 37 0.11
gi|4506797 ataxin 7 isoform a [Homo sapiens] 37 0.11
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 37 0.11
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 37 0.11
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens] 37 0.11
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens] 37 0.11
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 36 0.15
>gi|36949366 mutS homolog 4 [Homo sapiens]
Length = 936
Score = 1841 bits (4769), Expect = 0.0
Identities = 936/936 (100%), Positives = 936/936 (100%)
Query: 1 MLRPEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAA 60
MLRPEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAA
Sbjct: 1 MLRPEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAA 60
Query: 61 GDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT 120
GDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT
Sbjct: 61 GDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT 120
Query: 121 PLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKN 180
PLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKN
Sbjct: 121 PLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKN 180
Query: 181 PQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTI 240
PQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTI
Sbjct: 181 PQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTI 240
Query: 241 QRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLK 300
QRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLK
Sbjct: 241 QRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLK 300
Query: 301 ICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLV 360
ICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLV
Sbjct: 301 ICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLV 360
Query: 361 DIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITN 420
DIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITN
Sbjct: 361 DIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITN 420
Query: 421 LIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCL 480
LIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCL
Sbjct: 421 LIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCL 480
Query: 481 NMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQ 540
NMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQ
Sbjct: 481 NMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQ 540
Query: 541 MTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLL 600
MTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLL
Sbjct: 541 MTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLL 600
Query: 601 SEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAE 660
SEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAE
Sbjct: 601 SEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAE 660
Query: 661 KPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIF 720
KPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIF
Sbjct: 661 KPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIF 720
Query: 721 TRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEY 780
TRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEY
Sbjct: 721 TRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEY 780
Query: 781 LLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEE 840
LLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEE
Sbjct: 781 LLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEE 840
Query: 841 KNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTAR 900
KNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTAR
Sbjct: 841 KNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTAR 900
Query: 901 NSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE 936
NSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE
Sbjct: 901 NSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE 936
>gi|68303635 mutS homolog 3 [Homo sapiens]
Length = 1137
Score = 245 bits (625), Expect = 2e-64
Identities = 195/732 (26%), Positives = 365/732 (49%), Gaps = 74/732 (10%)
Query: 171 IGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLF----T 226
IG+ + +++ F D+ + +++ T++ L P+E+++ + A+ T+ T
Sbjct: 388 IGIVGVQPATGEVVFDSFQDSASRSELETRMSSLQPVELLLPS---ALSEQTEALIHRAT 444
Query: 227 LITENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEFSTV--------LMEVQSKYYCLAA 278
++ + + YF + + + + + + ++ ++ C +
Sbjct: 445 SVSVQDDRIRVERMDNIYFEYSHAFQAVTEFYAKDTVDIKGSQIISGIVNLEKPVIC--S 502
Query: 279 VAALLKYV-EF-IQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLF 336
+AA++KY+ EF ++ + P++ K + I+ ++ +NLE+L N D + +L
Sbjct: 503 LAAIIKYLKEFNLEKMLSKPENFKQ-LSSKMEFMTINGTTLRNLEILQNQTDMKTKGSLL 561
Query: 337 GVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFG-LQSVISRFLDT 395
VL++TKT G R+L+ + +PL+ + IN RLD V E+L E FG +++ + + D
Sbjct: 562 WVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSEVLHSESSVFGQIENHLRKLPDI 621
Query: 396 EQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLED 455
E+ L + K+ + + L +LK + + P + + LLR
Sbjct: 622 ERGLCSIYH--KKCSTQEFFLIVKTLYHLKSEFQAIIPA--VNSHIQSDLLRT------- 670
Query: 456 KRFGIILEKIKTVINDDARYMKGCLNMRTQKC---YAVRSNINEFLDIARRT--YTEIVD 510
+ILE I +++ Y+K LN + K + ++++F I +R ++D
Sbjct: 671 ----VILE-IPELLSPVEHYLK-ILNEQAAKVGDKTELFKDLSDFPLIKKRKDEIQGVID 724
Query: 511 DIAGMISQLGEKYSLPLRTSFS-SARGFFIQMTTDCIALPSDQLPSEFIKISKVKNSYSF 569
+I + ++ + P + S + F I++ ++ +P++++K+ K F
Sbjct: 725 EIRMHLQEIRKILKNPSAQYVTVSGQEFMIEIKNSAVSC----IPTDWVKVGSTKAVSRF 780
Query: 570 TSADLIKMNERCQESLREIYHMTYMIVCK-----LLSEIYEHIHCLYKLSDTVSMLDMLL 624
S +++ N R LRE ++ C L + EH H L K ++ +D +
Sbjct: 781 HSPFIVE-NYRHLNQLRE----QLVLDCSAEWLDFLEKFSEHYHSLCKAVHHLATVDCIF 835
Query: 625 SFAHACTLSDYVRPEFTDT--LAIKQGWHPILEKISAEKP--IANNTYVTEGSN-FLIIT 679
S A DY RP + + IK G HP+++ + E+ + NNT ++E S +IIT
Sbjct: 836 SLAKVAKQGDYCRPTVQEERKIVIKNGRHPVIDVLLGEQDQYVPNNTDLSEDSERVMIIT 895
Query: 680 GPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKE 739
GPNM GKS+Y+KQ+AL IMAQIGSYVPAE ++ I IFTR+ D+I STFM+E
Sbjct: 896 GPNMGGKSSYIKQVALITIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGRSTFMEE 955
Query: 740 MKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLL-SLKAFTLFATHFLELC 798
+ + A I+ A +SL+++DELGRGT+T +GI I YA EY + +K+ TLF TH+ +C
Sbjct: 956 LTDTAEIIRKATSQSLVILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPVC 1015
Query: 799 HIDALYPN-VENMHFEVQHVKNTSR--------NKEAILYTYKLSKGLTEEKNYGLKAAE 849
++ Y + V N H ++ S+ + + + Y++++G+ ++YGL A+
Sbjct: 1016 ELEKNYSHQVGNYHMGFLVSEDESKLDPGAAEQVPDFVTFLYQITRGIA-ARSYGLNVAK 1074
Query: 850 VSSLPPSIVLDA 861
++ +P I+ A
Sbjct: 1075 LADVPGEILKKA 1086
>gi|4557761 mutS homolog 2 [Homo sapiens]
Length = 934
Score = 207 bits (528), Expect = 3e-53
Identities = 194/716 (27%), Positives = 337/716 (47%), Gaps = 51/716 (7%)
Query: 170 EIGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIM--SNTACAVGNSTKLFT- 226
++G+ +D ++ L +F DN ++ + L + P E ++ TA +G ++
Sbjct: 160 QVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQR 219
Query: 227 ---LITENFKNVNFTT--IQRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAA 281
LITE K +F+T I + KG + EQ+ S VL E++++ +++++A
Sbjct: 220 GGILITER-KKADFSTKDIYQDLNRLLKGKKG-EQMN----SAVLPEMENQV-AVSSLSA 272
Query: 282 LLKYVEFIQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINN-QDYRNNHTLFGVLN 340
++K++E + + + F S Q +D ++ + L L + +D + +L +LN
Sbjct: 273 VIKFLELLSDDSNFGQFELTTFDFS-QYMKLDIAAVRALNLFQGSVEDTTGSQSLAALLN 331
Query: 341 YTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQS-VISRFLDTEQLL 399
KTP G R + I +PL+D I RL+ V+ ++D EL LQ ++ RF D +L
Sbjct: 332 KCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLA 391
Query: 400 SVLVQIPKQDTVNAAESKITNLIY--LKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKR 457
K+ AA + +Y + ++ L+ LL + L D R
Sbjct: 392 -------KKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLR 444
Query: 458 --FGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGM 515
F E I+T ++ D N + N++E +I ++ +
Sbjct: 445 SDFSKFQEMIETTLDMDQ-----VENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISA 499
Query: 516 ISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLI 575
LG ++ S+ G++ ++T C + F + KN FT++ L
Sbjct: 500 ARDLGLDPGKQIKLDSSAQFGYYFRVT--CKEEKVLRNNKNFSTVDIQKNGVKFTNSKLT 557
Query: 576 KMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSD- 634
+NE ++ E IV ++++ ++ + L+D ++ LD ++SFAH +
Sbjct: 558 SLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPV 617
Query: 635 -YVRPEFTDT----LAIKQGWHPILEKISAEKPIANNTYVTEGSN-FLIITGPNMSGKST 688
YVRP + + +K H +E I N+ Y + F IITGPNM GKST
Sbjct: 618 PYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKST 677
Query: 689 YLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKEMKEIAYILH 748
Y++Q + +MAQIG +VP E + I I R+ D STFM EM E A IL
Sbjct: 678 YIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILR 737
Query: 749 NANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS-LKAFTLFATHFLELCHIDALYPNV 807
+A SLI+IDELGRGT+T +G G+ +A+ EY+ + + AF +FATHF EL + P V
Sbjct: 738 SATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTV 797
Query: 808 ENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKE 863
N+H +E + Y++ KG+ ++ ++G+ AE+++ P ++ AK+
Sbjct: 798 NNLHV------TALTTEETLTMLYQVKKGVCDQ-SFGIHVAELANFPKHVIECAKQ 846
>gi|4505253 mutS homolog 5 isoform c [Homo sapiens]
Length = 834
Score = 143 bits (360), Expect = 9e-34
Identities = 144/558 (25%), Positives = 260/558 (46%), Gaps = 55/558 (9%)
Query: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFL 393
+LFG+LN G + LR P D+ ++ RLD +Q L + L + ++ R L
Sbjct: 253 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNL--DMAQMLHRLL 310
Query: 394 DTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC--NTPLLRAYYG 451
+ + ++++ K + +K+++ L T+ L+ A ++ + L R
Sbjct: 311 GHIKNVPLILKRMK-----LSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQ 365
Query: 452 SLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDD 511
D L I ++I + +G L + + V NI+ +D +R
Sbjct: 366 EFSDD-----LHHIASLIGKVVDF-EGSL---AENRFTVLPNIDPEIDEKKRRLM----G 412
Query: 512 IAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPS------------EFIK 559
+ ++++ K L + S +I + +++P +LPS +F+
Sbjct: 413 LPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIP--RLPSMVEASDFEINGLDFMF 470
Query: 560 ISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSM 619
+S+ K Y SA +++ + EI +++ +L ++ L ++ D S
Sbjct: 471 LSEEKLHYR--SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASR 528
Query: 620 LDMLLSFAHACTLSDYVRPEFTDTLA---IKQGWHPILEKISAEKPIANNTYVT-EGSNF 675
LD+LL+ A A Y RP ++ + I+ G HP++E + A + N+T +
Sbjct: 529 LDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLME-LCARTFVPNSTECGGDKGRV 587
Query: 676 LIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSST 735
+ITGPN SGKS YLKQ+ L MA +GS+VPAE + IFTRI + + I ST
Sbjct: 588 KVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLST 647
Query: 736 FMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS---LKAFTLFAT 792
FM ++ ++A ++NA +SL+LIDE G+GTNT +G+ + AV + L+ AT
Sbjct: 648 FMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVAT 707
Query: 793 HFLELCHIDAL--YPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEV 850
+FL L + L P V+ + E T + +++ Y++ +G+ + + AA+
Sbjct: 708 NFLSLVQLQLLPQGPLVQYLTME------TCEDGNDLVFFYQVCEGVAKASHASHTAAQ- 760
Query: 851 SSLPPSIVLDAKEITTQI 868
+ LP +V KE++ I
Sbjct: 761 AGLPDKLVARGKEVSDLI 778
>gi|26638662 mutS homolog 5 isoform a [Homo sapiens]
Length = 851
Score = 143 bits (360), Expect = 9e-34
Identities = 144/558 (25%), Positives = 260/558 (46%), Gaps = 55/558 (9%)
Query: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFL 393
+LFG+LN G + LR P D+ ++ RLD +Q L + L + ++ R L
Sbjct: 270 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNL--DMAQMLHRLL 327
Query: 394 DTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC--NTPLLRAYYG 451
+ + ++++ K + +K+++ L T+ L+ A ++ + L R
Sbjct: 328 GHIKNVPLILKRMK-----LSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQ 382
Query: 452 SLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDD 511
D L I ++I + +G L + + V NI+ +D +R
Sbjct: 383 EFSDD-----LHHIASLIGKVVDF-EGSL---AENRFTVLPNIDPEIDEKKRRLM----G 429
Query: 512 IAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPS------------EFIK 559
+ ++++ K L + S +I + +++P +LPS +F+
Sbjct: 430 LPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIP--RLPSMVEASDFEINGLDFMF 487
Query: 560 ISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSM 619
+S+ K Y SA +++ + EI +++ +L ++ L ++ D S
Sbjct: 488 LSEEKLHYR--SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASR 545
Query: 620 LDMLLSFAHACTLSDYVRPEFTDTLA---IKQGWHPILEKISAEKPIANNTYVT-EGSNF 675
LD+LL+ A A Y RP ++ + I+ G HP++E + A + N+T +
Sbjct: 546 LDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLME-LCARTFVPNSTECGGDKGRV 604
Query: 676 LIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSST 735
+ITGPN SGKS YLKQ+ L MA +GS+VPAE + IFTRI + + I ST
Sbjct: 605 KVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLST 664
Query: 736 FMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS---LKAFTLFAT 792
FM ++ ++A ++NA +SL+LIDE G+GTNT +G+ + AV + L+ AT
Sbjct: 665 FMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVAT 724
Query: 793 HFLELCHIDAL--YPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEV 850
+FL L + L P V+ + E T + +++ Y++ +G+ + + AA+
Sbjct: 725 NFLSLVQLQLLPQGPLVQYLTME------TCEDGNDLVFFYQVCEGVAKASHASHTAAQ- 777
Query: 851 SSLPPSIVLDAKEITTQI 868
+ LP +V KE++ I
Sbjct: 778 AGLPDKLVARGKEVSDLI 795
>gi|26638666 mutS homolog 5 isoform c [Homo sapiens]
Length = 834
Score = 143 bits (360), Expect = 9e-34
Identities = 144/558 (25%), Positives = 260/558 (46%), Gaps = 55/558 (9%)
Query: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFL 393
+LFG+LN G + LR P D+ ++ RLD +Q L + L + ++ R L
Sbjct: 253 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNL--DMAQMLHRLL 310
Query: 394 DTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC--NTPLLRAYYG 451
+ + ++++ K + +K+++ L T+ L+ A ++ + L R
Sbjct: 311 GHIKNVPLILKRMK-----LSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQ 365
Query: 452 SLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDD 511
D L I ++I + +G L + + V NI+ +D +R
Sbjct: 366 EFSDD-----LHHIASLIGKVVDF-EGSL---AENRFTVLPNIDPEIDEKKRRLM----G 412
Query: 512 IAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPS------------EFIK 559
+ ++++ K L + S +I + +++P +LPS +F+
Sbjct: 413 LPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIP--RLPSMVEASDFEINGLDFMF 470
Query: 560 ISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSM 619
+S+ K Y SA +++ + EI +++ +L ++ L ++ D S
Sbjct: 471 LSEEKLHYR--SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASR 528
Query: 620 LDMLLSFAHACTLSDYVRPEFTDTLA---IKQGWHPILEKISAEKPIANNTYVT-EGSNF 675
LD+LL+ A A Y RP ++ + I+ G HP++E + A + N+T +
Sbjct: 529 LDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLME-LCARTFVPNSTECGGDKGRV 587
Query: 676 LIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSST 735
+ITGPN SGKS YLKQ+ L MA +GS+VPAE + IFTRI + + I ST
Sbjct: 588 KVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLST 647
Query: 736 FMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS---LKAFTLFAT 792
FM ++ ++A ++NA +SL+LIDE G+GTNT +G+ + AV + L+ AT
Sbjct: 648 FMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVAT 707
Query: 793 HFLELCHIDAL--YPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEV 850
+FL L + L P V+ + E T + +++ Y++ +G+ + + AA+
Sbjct: 708 NFLSLVQLQLLPQGPLVQYLTME------TCEDGNDLVFFYQVCEGVAKASHASHTAAQ- 760
Query: 851 SSLPPSIVLDAKEITTQI 868
+ LP +V KE++ I
Sbjct: 761 AGLPDKLVARGKEVSDLI 778
>gi|26638664 mutS homolog 5 isoform b [Homo sapiens]
Length = 835
Score = 139 bits (349), Expect = 2e-32
Identities = 144/559 (25%), Positives = 261/559 (46%), Gaps = 56/559 (10%)
Query: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFL 393
+LFG+LN G + LR P D+ ++ RLD +Q L + L + ++ R L
Sbjct: 253 SLFGILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNL--DMAQMLHRLL 310
Query: 394 DTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC--NTPLLRAYYG 451
+ + ++++ K + +K+++ L T+ L+ A ++ + L R
Sbjct: 311 GHIKNVPLILKRMK-----LSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFRDIAQ 365
Query: 452 SLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDD 511
D L I ++I + +G L + + V NI+ +D +R
Sbjct: 366 EFSDD-----LHHIASLIGKVVDF-EGSL---AENRFTVLPNIDPEIDEKKRRLM----G 412
Query: 512 IAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPS------------EFIK 559
+ ++++ K L + S +I + +++P +LPS +F+
Sbjct: 413 LPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIP--RLPSMVEASDFEINGLDFMF 470
Query: 560 ISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSM 619
+S+ K Y SA +++ + EI +++ +L ++ L ++ D S
Sbjct: 471 LSEEKLHYR--SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASR 528
Query: 620 LDMLLSFAHACTLSDYVRPEFTDTLA---IKQGWHPILEKISAEKPIANNTYVT-EGSNF 675
LD+LL+ A A Y RP ++ + I+ G HP++E + A + N+T +
Sbjct: 529 LDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLME-LCARTFVPNSTECGGDKGRV 587
Query: 676 LIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSST 735
+ITGPN SGKS YLKQ+ L MA +GS+VPAE + IFTRI + + I ST
Sbjct: 588 KVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLST 647
Query: 736 FMKEM-KEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLS---LKAFTLFA 791
FM ++ +++A ++NA +SL+LIDE G+GTNT +G+ + AV + L+ A
Sbjct: 648 FMIDLNQQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVA 707
Query: 792 THFLELCHIDAL--YPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAE 849
T+FL L + L P V+ + E T + +++ Y++ +G+ + + AA+
Sbjct: 708 TNFLSLVQLQLLPQGPLVQYLTME------TCEDGNDLVFFYQVCEGVAKASHASHTAAQ 761
Query: 850 VSSLPPSIVLDAKEITTQI 868
+ LP +V KE++ I
Sbjct: 762 -AGLPDKLVARGKEVSDLI 779
>gi|4504191 mutS homolog 6 [Homo sapiens]
Length = 1360
Score = 129 bits (324), Expect = 1e-29
Identities = 106/371 (28%), Positives = 165/371 (44%), Gaps = 51/371 (13%)
Query: 572 ADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACT 631
A+LI ER SL++ + K + + C +++LD+LL A+
Sbjct: 1016 ANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVEC-------IAVLDVLLCLANYSR 1068
Query: 632 LSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSNFL--------------- 676
D P + + + P LE + P T+ G +F+
Sbjct: 1069 GGD--GPMCRPVILLPEDTPPFLELKGSRHPCITKTFF--GDDFIPNDILIGCEEEEQEN 1124
Query: 677 ------IITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIE 730
++TGPNM GKST ++Q L +MAQ+G YVPAE ++FTR+ D I
Sbjct: 1125 GKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIM 1184
Query: 731 TNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLL-SLKAFTL 789
+ STF E+ E A IL +A SL+L+DELGRGT T +G I AV + L ++K TL
Sbjct: 1185 SGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTL 1244
Query: 790 FATHFLELCHIDALYPNVENMHFEVQHVKNTSR--NKEAILYTYKLSKGLTEEKNYGLKA 847
F+TH+ L + V H V+N ++E I + YK KG K+YG A
Sbjct: 1245 FSTHYHSLVEDYSQNVAVRLGHMACM-VENECEDPSQETITFLYKFIKGAC-PKSYGFNA 1302
Query: 848 AEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTARNSQLDPD 907
A +++LP + I + R E E+ L + + S +D +
Sbjct: 1303 ARLANLPEEV--------------IQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAE 1348
Query: 908 SLRIYLSNLKK 918
++ L+ +K+
Sbjct: 1349 AVHKLLTLIKE 1359
Score = 49.3 bits (116), Expect = 2e-05
Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 1/125 (0%)
Query: 276 LAAVAALLKYVEFIQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTL 335
L ++A +Y+ ++V +S I F + Q ++D+ + NLE+ +N + TL
Sbjct: 700 LLSMANFEEYIPLDSDTVSTTRSGAI-FTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTL 758
Query: 336 FGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFLDT 395
++ TP G R L+ + PL + IN RLD +++L+ + + ++ + D
Sbjct: 759 LERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDL 818
Query: 396 EQLLS 400
E+LLS
Sbjct: 819 ERLLS 823
>gi|58530845 zyxin [Homo sapiens]
Length = 572
Score = 46.2 bits (108), Expect = 1e-04
Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 21/135 (15%)
Query: 3 RPEISSTSPSAPAVSPSSGE----TRSPQGPRYNFGLQETPQSRPSVQV-VSASTCPGTS 57
+P T+P P SPSS + +P + F +Q PQ +P VQ+ V + T P +
Sbjct: 188 KPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSL 247
Query: 58 GAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTN---- 113
R +SS P PAP P + VAS F+ GA S N
Sbjct: 248 ANTQPRGPPASS-PAPAPKFSPVTPKF---------TPVASKFSPGAPGGSGSQPNQKLG 297
Query: 114 YPQTLKTPLSTGNPQ 128
+P+ L TG+PQ
Sbjct: 298 HPEALSA--GTGSPQ 310
>gi|4508047 zyxin [Homo sapiens]
Length = 572
Score = 46.2 bits (108), Expect = 1e-04
Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 21/135 (15%)
Query: 3 RPEISSTSPSAPAVSPSSGE----TRSPQGPRYNFGLQETPQSRPSVQV-VSASTCPGTS 57
+P T+P P SPSS + +P + F +Q PQ +P VQ+ V + T P +
Sbjct: 188 KPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSL 247
Query: 58 GAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTN---- 113
R +SS P PAP P + VAS F+ GA S N
Sbjct: 248 ANTQPRGPPASS-PAPAPKFSPVTPKF---------TPVASKFSPGAPGGSGSQPNQKLG 297
Query: 114 YPQTLKTPLSTGNPQ 128
+P+ L TG+PQ
Sbjct: 298 HPEALSA--GTGSPQ 310
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 4 PEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQV---------VSASTCP 54
P S+ P AP + G+ GP F P+S Q S+S+
Sbjct: 2506 PAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSS 2565
Query: 55 GTSGAAGDRSSSSSSLPCPAPNSRPAQGSY-FGNKRAYAENTVASNFTFGASSSSARDTN 113
G+S ++ SSS S + G G + A ++ A++ +SSSS+ ++
Sbjct: 2566 GSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSS 2625
Query: 114 YPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155
+ + S+ + S S + S+SSSS+ S+ S S
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2667
Score = 33.1 bits (74), Expect = 1.2
Identities = 35/153 (22%), Positives = 66/153 (43%), Gaps = 9/153 (5%)
Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66
SS+S S+ + S + GE + G S S + S ++ +S ++ SSS
Sbjct: 2569 SSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSS 2628
Query: 67 SSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT-----P 121
SSS + +S + S + + + ++ +S+ + +SSSS+ T+ + + P
Sbjct: 2629 SSS-SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687
Query: 122 LSTGNPQRSGYKSWTPQVGYSASSSSAISAHSP 154
T P ++ P + + SAHSP
Sbjct: 2688 APTAGPSA---QAALPTKATKQAGKARPSAHSP 2717
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 41.2 bits (95), Expect = 0.005
Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 13/165 (7%)
Query: 2 LRPEISSTSP---------SAPAVSPSSGETR--SPQGPRYNFGLQETPQSRPSVQVVSA 50
+R SSTSP + + SPS G+T SP+G + + + +P +R + Q+ +
Sbjct: 2236 VRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGS 2295
Query: 51 STCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSAR 110
S P SG+ S + P P P + S + + S +S S+A
Sbjct: 2296 SKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAS 2355
Query: 111 DTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155
+ + S G ++ ++ T Q G S ++SS + S S
Sbjct: 2356 TKSSGSGKMSYTSPG--RQMSQQNLTKQTGLSKNASSIPRSESAS 2398
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 41.2 bits (95), Expect = 0.005
Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 13/165 (7%)
Query: 2 LRPEISSTSP---------SAPAVSPSSGETR--SPQGPRYNFGLQETPQSRPSVQVVSA 50
+R SSTSP + + SPS G+T SP+G + + + +P +R + Q+ +
Sbjct: 2236 VRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGS 2295
Query: 51 STCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSAR 110
S P SG+ S + P P P + S + + S +S S+A
Sbjct: 2296 SKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAS 2355
Query: 111 DTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155
+ + S G ++ ++ T Q G S ++SS + S S
Sbjct: 2356 TKSSGSGKMSYTSPG--RQMSQQNLTKQTGLSKNASSIPRSESAS 2398
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 41.2 bits (95), Expect = 0.005
Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 13/165 (7%)
Query: 2 LRPEISSTSP---------SAPAVSPSSGETR--SPQGPRYNFGLQETPQSRPSVQVVSA 50
+R SSTSP + + SPS G+T SP+G + + + +P +R + Q+ +
Sbjct: 2236 VRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGS 2295
Query: 51 STCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSAR 110
S P SG+ S + P P P + S + + S +S S+A
Sbjct: 2296 SKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAS 2355
Query: 111 DTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155
+ + S G ++ ++ T Q G S ++SS + S S
Sbjct: 2356 TKSSGSGKMSYTSPG--RQMSQQNLTKQTGLSKNASSIPRSESAS 2398
>gi|24430146 nucleoporin 153kDa [Homo sapiens]
Length = 1475
Score = 41.2 bits (95), Expect = 0.005
Identities = 36/142 (25%), Positives = 57/142 (40%), Gaps = 28/142 (19%)
Query: 6 ISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSS 65
+ T PSAP+ SP+ G ++P + Q P S+ +A G+ A +
Sbjct: 1305 VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGT 1364
Query: 66 SSSSLPCPAPNSRPAQGSY-------------FGNKRA---YAENTVASNFTFGASSSSA 109
SSS P +P+Q ++ FG+ + N+ + FTFGA+SS
Sbjct: 1365 VSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS-- 1422
Query: 110 RDTNYPQTLKTPLSTGNPQRSG 131
TP ++ P SG
Sbjct: 1423 ----------TPAASAQPSGSG 1434
Score = 30.4 bits (67), Expect = 8.1
Identities = 36/114 (31%), Positives = 50/114 (43%), Gaps = 22/114 (19%)
Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQ--VVSASTCPGTSGAAGDRS 64
SS+S S PA S G FG T S P V V S+ P +S A G+ +
Sbjct: 1196 SSSSSSTPATSAGGGI----------FG-SSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244
Query: 65 SSSSSLPCP-APNSRPAQGSYFGNK--------RAYAENTVASNFTFGASSSSA 109
SS+S + +S+ A S G A + NT S F FGA+++S+
Sbjct: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSS 1298
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 39.7 bits (91), Expect = 0.013
Identities = 47/165 (28%), Positives = 65/165 (39%), Gaps = 15/165 (9%)
Query: 4 PEISSTSPSAPAVSPSSGETR---SPQGPRYNFGLQETPQSRPSVQVVSAS---TCPGTS 57
P S TSPS SPS T SP P Y+ + PS S S T P S
Sbjct: 1634 PNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1693
Query: 58 GAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQT 117
+ S +S S +P+ P SY +Y+ + + + T + S S NY T
Sbjct: 1694 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT--SPSYSPTSPNYSPT 1751
Query: 118 LK--TPLSTG-NPQRSGYK----SWTPQVGYSASSSSAISAHSPS 155
TP S +P Y ++TP + +S + S SPS
Sbjct: 1752 SPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPS 1796
Score = 38.5 bits (88), Expect = 0.030
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 5/151 (3%)
Query: 8 STSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVS---ASTCPGTSGAAGDRS 64
S SP++PA P S +PQ P Y+ + PS S + T P S + S
Sbjct: 1592 SYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYS 1651
Query: 65 SSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLST 124
+S S +P+ P SY +Y+ + + + T + S S +Y T + T
Sbjct: 1652 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT--SPSYSPTSPSYSPTSPSYSPT 1709
Query: 125 GNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155
S++P + +S + S SPS
Sbjct: 1710 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1740
Score = 38.1 bits (87), Expect = 0.039
Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 13/162 (8%)
Query: 4 PEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSAS---TCPGTSGAA 60
P+ S SP++P+ SP+S + SP P Y+ + PS S S T P S +
Sbjct: 1610 PQSPSYSPTSPSYSPTS-PSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1668
Query: 61 GDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKT 120
S +S S +P+ P SY +Y+ + + + T + S ++ + +
Sbjct: 1669 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1728
Query: 121 PLSTG-NPQRSGYKSWTPQVGYSASS------SSAISAHSPS 155
P S +P Y +P YS +S S + S SPS
Sbjct: 1729 PTSPSYSPTSPSYSPTSP--NYSPTSPNYTPTSPSYSPTSPS 1768
Score = 35.4 bits (80), Expect = 0.25
Identities = 42/165 (25%), Positives = 56/165 (33%), Gaps = 14/165 (8%)
Query: 4 PEISSTSPSAPAVSPSSGETR---SPQGPRYNFGLQETPQSRPSVQVVSAS---TCPGTS 57
P S TSPS SPS T SP PRY S PS S S T P +
Sbjct: 1781 PNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYT 1840
Query: 58 GAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQT 117
+ S SS +P P Y Y+ + + T S ++ +
Sbjct: 1841 PTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSP 1900
Query: 118 LKTPLS--------TGNPQRSGYKSWTPQVGYSASSSSAISAHSP 154
+ TP S T +P Y +P ++ S S SP
Sbjct: 1901 VYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSP 1945
Score = 32.0 bits (71), Expect = 2.8
Identities = 39/149 (26%), Positives = 56/149 (37%), Gaps = 8/149 (5%)
Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66
S +P A SPS+ S P Y+ TP S P S+ P GA S
Sbjct: 1537 SGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGS-PGSPGPSSPYIPSPGGAMSPSYSP 1595
Query: 67 SSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126
+S P P S G Y +Y+ + + + T + S S NY T + T
Sbjct: 1596 TS--PAYEPRS---PGGYTPQSPSYSPTSPSYSPT--SPSYSPTSPNYSPTSPSYSPTSP 1648
Query: 127 PQRSGYKSWTPQVGYSASSSSAISAHSPS 155
S++P + +S + S SPS
Sbjct: 1649 SYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1677
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 38.5 bits (88), Expect = 0.030
Identities = 43/164 (26%), Positives = 69/164 (42%), Gaps = 21/164 (12%)
Query: 12 SAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSLP 71
S P +PS G T P + + TP + ++S T P S S+ +SS P
Sbjct: 3211 SIPTSTPSEGMT-----PLTSVPVSNTPVASSEASILS--TTPVDSNTPLTTSTEASSSP 3263
Query: 72 CPA-----PNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126
A P S P++GS + TVAS+ T S++ A DT+ P T + S+
Sbjct: 3264 PTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPA-DTSTPVTTYSQASSSP 3322
Query: 127 PQRSG--------YKSWTPQVGYSASSSSAISAHSPSVIVAVVE 162
P G + TP S S++ +S+ + ++ V+
Sbjct: 3323 PIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVD 3366
Score = 34.7 bits (78), Expect = 0.43
Identities = 39/146 (26%), Positives = 59/146 (40%), Gaps = 6/146 (4%)
Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66
+S S P +PS G T P + + S S V ST TS A +SS
Sbjct: 3148 TSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEA---TSS 3204
Query: 67 SSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126
+++ P S P++G + VAS+ S++ D+N P T T S+
Sbjct: 3205 TTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEA-SILSTTPVDSNTPLTTSTEASSSP 3263
Query: 127 PQRSG--YKSWTPQVGYSASSSSAIS 150
P G + TP G + +S +S
Sbjct: 3264 PTAEGTSMPTSTPSEGSTPLTSMPVS 3289
Score = 33.1 bits (74), Expect = 1.2
Identities = 46/216 (21%), Positives = 86/216 (39%), Gaps = 36/216 (16%)
Query: 5 EISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRS 64
E +S+ +A +S + + P + + TP + + ST P S + S
Sbjct: 1432 EATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTL--STTPVDSNSPVVTS 1489
Query: 65 SSSSSLPCPAPN-----SRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLK 119
++ SS P PA S P++GS + TVAS+ S++ P
Sbjct: 1490 TAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTT-------PAVTS 1542
Query: 120 TPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLK 179
TP++T YS +SSS +A S+ + + G + S+ +
Sbjct: 1543 TPVTT----------------YSQASSSPTTADGTSMQTST-----YSEGSTPLTSLPV- 1580
Query: 180 NPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTA 215
+ +++S A+ + + +K ++ + E S TA
Sbjct: 1581 STMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTA 1616
Score = 32.0 bits (71), Expect = 2.8
Identities = 45/192 (23%), Positives = 75/192 (39%), Gaps = 11/192 (5%)
Query: 7 SSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66
SST+ +++ S+ SP + + TP + P +S T P S + S+
Sbjct: 1612 SSTTAEGSSMTISTPSEGSPL--LTSIPVSTTPVASPEASTLS--TTPVDSNSPVITSTE 1667
Query: 67 SSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126
SS P PA + +Y + TV + T ASS+ + + P TP++T
Sbjct: 1668 VSSSPTPAEGTSMPTSTYTEGRTPLTSITVRT--TPVASSAISTLSTTPVDNSTPVTTST 1725
Query: 127 PQRSGYKSWTPQVGYSASSSSAISAHSP--SVIVAVVEGRGLARGEIGMASIDLKNPQII 184
RS S T G S +S+ +P S+ V+ + ID P
Sbjct: 1726 EARS---SPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTT 1782
Query: 185 LSQFADNTTYAK 196
++ + T A+
Sbjct: 1783 STEATSSPTTAE 1794
Score = 31.2 bits (69), Expect = 4.7
Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 15/151 (9%)
Query: 7 SSTSP---SAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63
SST+P S P +PS G T P N + + + S + + ST P S
Sbjct: 551 SSTTPEGTSIPTSTPSEGST-----PLTN--MPVSTRLVVSSEASTTSTTPADSNTFVTT 603
Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLS 123
SS +SS A + +Y ++R +++ + T ASS ++ + P TP++
Sbjct: 604 SSEASSSSTTAEGTSMPTSTY--SERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT 661
Query: 124 TGNPQRSGYKSWTPQVGYSASSSSAISAHSP 154
T S S T G S +S+ +P
Sbjct: 662 TSTEATS---SSTTAEGTSMPTSTYTEGSTP 689
>gi|239753437 PREDICTED: hypothetical protein [Homo sapiens]
Length = 157
Score = 37.7 bits (86), Expect = 0.050
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 28/135 (20%)
Query: 16 VSPSSGETRSPQGPRYNF-------GLQETPQSRPSV---QVVSASTCPGTSGAAGDRSS 65
++ G+++ P GP +F G +P P++ ++ S G +GAA R++
Sbjct: 3 INGKKGQSQCPGGPGASFTWALSLRGTALSPGELPALWHHHLLVQSQDRGRAGAA--RTT 60
Query: 66 SSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTG 125
S SLP P SRPA G+K+ T+ +S + T + +K PL+
Sbjct: 61 KSESLPAPPATSRPAA----GDKKPLQGQTL-------RRASGLQATGRAEEVKPPLA-- 107
Query: 126 NPQRSGYKSWTPQVG 140
G+ W PQ G
Sbjct: 108 ---HQGHAPWEPQNG 119
>gi|239748002 PREDICTED: hypothetical protein [Homo sapiens]
Length = 157
Score = 37.7 bits (86), Expect = 0.050
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 28/135 (20%)
Query: 16 VSPSSGETRSPQGPRYNF-------GLQETPQSRPSV---QVVSASTCPGTSGAAGDRSS 65
++ G+++ P GP +F G +P P++ ++ S G +GAA R++
Sbjct: 3 INGKKGQSQCPGGPGASFTWALSLRGTALSPGELPALWHHHLLVQSQDRGRAGAA--RTT 60
Query: 66 SSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTG 125
S SLP P SRPA G+K+ T+ +S + T + +K PL+
Sbjct: 61 KSESLPAPPATSRPAA----GDKKPLQGQTL-------RRASGLQATGRAEEVKPPLA-- 107
Query: 126 NPQRSGYKSWTPQVG 140
G+ W PQ G
Sbjct: 108 ---HQGHAPWEPQNG 119
>gi|239741900 PREDICTED: hypothetical protein XP_002342343 [Homo
sapiens]
Length = 157
Score = 37.7 bits (86), Expect = 0.050
Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 28/135 (20%)
Query: 16 VSPSSGETRSPQGPRYNF-------GLQETPQSRPSV---QVVSASTCPGTSGAAGDRSS 65
++ G+++ P GP +F G +P P++ ++ S G +GAA R++
Sbjct: 3 INGKKGQSQCPGGPGASFTWALSLRGTALSPGELPALWHHHLLVQSQDRGRAGAA--RTT 60
Query: 66 SSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTG 125
S SLP P SRPA G+K+ T+ +S + T + +K PL+
Sbjct: 61 KSESLPAPPATSRPAA----GDKKPLQGQTL-------RRASGLQATGRAEEVKPPLA-- 107
Query: 126 NPQRSGYKSWTPQVG 140
G+ W PQ G
Sbjct: 108 ---HQGHAPWEPQNG 119
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 37.4 bits (85), Expect = 0.066
Identities = 46/167 (27%), Positives = 60/167 (35%), Gaps = 23/167 (13%)
Query: 9 TSPSAP--AVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSS 66
TSP P A SG T P R TP S PS +++ P S G S
Sbjct: 2381 TSPRVPLSAYERVSGRTSPPLLDRAR---SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ 2437
Query: 67 SSSLPC------PAPNS------------RPAQGSYFGNKRAYAENTVASNFTFGASSSS 108
S P P P++ P GS + A A T ++ G S
Sbjct: 2438 SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP 2497
Query: 109 ARDTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155
A + + P STG Q S + P +SSSS+ S+ S S
Sbjct: 2498 APGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544
Score = 37.4 bits (85), Expect = 0.066
Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 9/155 (5%)
Query: 7 SSTSPSAPAVSPSSGETRS-------PQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGA 59
SS+S S+ + S SSG + S P P +P P V T
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAK 2602
Query: 60 AGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLK 119
RSSSSSS + +S + S + + + ++ +S+ + +S S A+ PQ L
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG--PQALP 2660
Query: 120 TPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSP 154
P S P +S +P+ + S ++SP
Sbjct: 2661 KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSP 2695
Score = 36.6 bits (83), Expect = 0.11
Identities = 48/160 (30%), Positives = 67/160 (41%), Gaps = 13/160 (8%)
Query: 4 PEISSTSPSAPAVSPSSGETR--SPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAG 61
PE SST P PA +P E SPQ P L + P + PS + P S
Sbjct: 354 PERSSTGPEPPAPTPLLAERHGGSPQ-PLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL 412
Query: 62 DRSSSS-SSLPCPAPN--SRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTL 118
+SSSS SS P P P SR A S K A A + +SS ++++ ++ +
Sbjct: 413 PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI----SSSPTSKNRSHGRAK 468
Query: 119 KTPLSTGNPQRSGYKSWTPQV---GYSASSSSAISAHSPS 155
+ + P R +S +P G S S + HS S
Sbjct: 469 RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRS 508
Score = 31.6 bits (70), Expect = 3.6
Identities = 42/162 (25%), Positives = 64/162 (39%), Gaps = 27/162 (16%)
Query: 5 EISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRS 64
++ S A PS+ P R + + S S S+S+ +S ++G S
Sbjct: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS----SSSSSSSSSSSSGSSS 2560
Query: 65 SSS--SSLPC---------PAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTN 113
S S SSLP P+P P + G E T A +SSSS+ ++
Sbjct: 2561 SDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP---PEPTPAKRKRRSSSSSSSSSSS 2617
Query: 114 YPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPS 155
S+ + S S + S+SSSS+ S+ SPS
Sbjct: 2618 ---------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
>gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]
Length = 922
Score = 37.0 bits (84), Expect = 0.086
Identities = 43/158 (27%), Positives = 66/158 (41%), Gaps = 22/158 (13%)
Query: 4 PEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63
P S++P AP + T NF L P PSV + PG+ A
Sbjct: 660 PPHGSSTPIAPVFTALPSFTSLTN----NFPLTGNPSLNPSVSL------PGSLIATSST 709
Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLS 123
+++S+SLP P+ + G + + S F + S+A + + T + PLS
Sbjct: 710 AATSTSLPHPSSTAAVLSG--------LSASAPVSAAPFPLNLSTAVPSLFSVT-QGPLS 760
Query: 124 TGNPQRSGYK-SWTPQVGYSASSSSAISAHSPSVIVAV 160
+ NP G+ S TP V + S + A PS + AV
Sbjct: 761 SSNPSYPGFSVSNTPSVTPALPSFPGLQA--PSTVAAV 796
Score = 31.6 bits (70), Expect = 3.6
Identities = 37/166 (22%), Positives = 63/166 (37%), Gaps = 24/166 (14%)
Query: 6 ISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCP------GTSGA 59
+++ P P S+ T P P + + P + S +T P G
Sbjct: 287 LNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTTTPVPSIFSGLVSL 346
Query: 60 AGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQT-- 117
G ++ +++ P P P R S G+ A+A + ++SSSA T+ P +
Sbjct: 347 PGPSATPTAATPTPGPTPR----STLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSAS 402
Query: 118 -------LKTPLSTGNPQRSGYKSWTPQV--GYSASSSSAISAHSP 154
L PL P G + TP + G + S + + +SP
Sbjct: 403 LSSVFAGLPLPLP---PTSQGLSNPTPVIAGGSTPSVAGPLGVNSP 445
>gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]
Length = 944
Score = 37.0 bits (84), Expect = 0.086
Identities = 43/158 (27%), Positives = 66/158 (41%), Gaps = 22/158 (13%)
Query: 4 PEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63
P S++P AP + T NF L P PSV + PG+ A
Sbjct: 682 PPHGSSTPIAPVFTALPSFTSLTN----NFPLTGNPSLNPSVSL------PGSLIATSST 731
Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLS 123
+++S+SLP P+ + G + + S F + S+A + + T + PLS
Sbjct: 732 AATSTSLPHPSSTAAVLSG--------LSASAPVSAAPFPLNLSTAVPSLFSVT-QGPLS 782
Query: 124 TGNPQRSGYK-SWTPQVGYSASSSSAISAHSPSVIVAV 160
+ NP G+ S TP V + S + A PS + AV
Sbjct: 783 SSNPSYPGFSVSNTPSVTPALPSFPGLQA--PSTVAAV 818
Score = 31.6 bits (70), Expect = 3.6
Identities = 37/166 (22%), Positives = 63/166 (37%), Gaps = 24/166 (14%)
Query: 6 ISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCP------GTSGA 59
+++ P P S+ T P P + + P + S +T P G
Sbjct: 309 LNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTTTPVPSIFSGLVSL 368
Query: 60 AGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQT-- 117
G ++ +++ P P P R S G+ A+A + ++SSSA T+ P +
Sbjct: 369 PGPSATPTAATPTPGPTPR----STLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSAS 424
Query: 118 -------LKTPLSTGNPQRSGYKSWTPQV--GYSASSSSAISAHSP 154
L PL P G + TP + G + S + + +SP
Sbjct: 425 LSSVFAGLPLPLP---PTSQGLSNPTPVIAGGSTPSVAGPLGVNSP 467
>gi|189491742 ataxin 7 isoform b [Homo sapiens]
Length = 945
Score = 36.6 bits (83), Expect = 0.11
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 5/94 (5%)
Query: 7 SSTSPSAPA---VSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63
SS+SPS P+ PSS +R PQ + + L+ S S +AS+ TSG +G +
Sbjct: 649 SSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASS--STSGGSGKK 706
Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVA 97
+SS L + +S + S + ++ +N VA
Sbjct: 707 RKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVA 740
>gi|4506797 ataxin 7 isoform a [Homo sapiens]
Length = 892
Score = 36.6 bits (83), Expect = 0.11
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 5/94 (5%)
Query: 7 SSTSPSAPA---VSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDR 63
SS+SPS P+ PSS +R PQ + + L+ S S +AS+ TSG +G +
Sbjct: 649 SSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASS--STSGGSGKK 706
Query: 64 SSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVA 97
+SS L + +S + S + ++ +N VA
Sbjct: 707 RKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVA 740
>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
Length = 1083
Score = 36.6 bits (83), Expect = 0.11
Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 20/187 (10%)
Query: 14 PAVSPSS-GETRSPQGPRYN--FGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSL 70
P SP + G T +PQ P Y Q PQ P A S S
Sbjct: 840 PTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQ 899
Query: 71 PCPAPNS----RPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126
P P+P S P+ Y + + S + AS S + Y +P++ G
Sbjct: 900 PSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPS-PVGY-----SPMTPGA 953
Query: 127 PQRSGYKSWTPQVGYSASSSS------AISAHSPSVIVAVVEGRGLARGEI-GMASIDLK 179
P GY TP G +SS + + VV G+ R GM S+ LK
Sbjct: 954 PSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLK 1013
Query: 180 NPQIILS 186
+ + ++S
Sbjct: 1014 DSEKVVS 1020
>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 36.6 bits (83), Expect = 0.11
Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 20/187 (10%)
Query: 14 PAVSPSS-GETRSPQGPRYN--FGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSL 70
P SP + G T +PQ P Y Q PQ P A S S
Sbjct: 844 PTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQ 903
Query: 71 PCPAPNS----RPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126
P P+P S P+ Y + + S + AS S + Y +P++ G
Sbjct: 904 PSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPS-PVGY-----SPMTPGA 957
Query: 127 PQRSGYKSWTPQVGYSASSSS------AISAHSPSVIVAVVEGRGLARGEI-GMASIDLK 179
P GY TP G +SS + + VV G+ R GM S+ LK
Sbjct: 958 PSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLK 1017
Query: 180 NPQIILS 186
+ + ++S
Sbjct: 1018 DSEKVVS 1024
>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 36.6 bits (83), Expect = 0.11
Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 20/187 (10%)
Query: 14 PAVSPSS-GETRSPQGPRYN--FGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSL 70
P SP + G T +PQ P Y Q PQ P A S S
Sbjct: 844 PTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQ 903
Query: 71 PCPAPNS----RPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126
P P+P S P+ Y + + S + AS S + Y +P++ G
Sbjct: 904 PSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPS-PVGY-----SPMTPGA 957
Query: 127 PQRSGYKSWTPQVGYSASSSS------AISAHSPSVIVAVVEGRGLARGEI-GMASIDLK 179
P GY TP G +SS + + VV G+ R GM S+ LK
Sbjct: 958 PSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLK 1017
Query: 180 NPQIILS 186
+ + ++S
Sbjct: 1018 DSEKVVS 1024
>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 36.6 bits (83), Expect = 0.11
Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 20/187 (10%)
Query: 14 PAVSPSS-GETRSPQGPRYN--FGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSL 70
P SP + G T +PQ P Y Q PQ P A S S
Sbjct: 844 PTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQ 903
Query: 71 PCPAPNS----RPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGN 126
P P+P S P+ Y + + S + AS S + Y +P++ G
Sbjct: 904 PSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPS-PVGY-----SPMTPGA 957
Query: 127 PQRSGYKSWTPQVGYSASSSS------AISAHSPSVIVAVVEGRGLARGEI-GMASIDLK 179
P GY TP G +SS + + VV G+ R GM S+ LK
Sbjct: 958 PSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLK 1017
Query: 180 NPQIILS 186
+ + ++S
Sbjct: 1018 DSEKVVS 1024
>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
Length = 518
Score = 36.2 bits (82), Expect = 0.15
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 4/81 (4%)
Query: 4 PEISSTSPSAPAVSPS----SGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGA 59
PEIS T+PS P SP+ SGE + +G +T + P+ ++ GT A
Sbjct: 337 PEISVTTPSQPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPA 396
Query: 60 AGDRSSSSSSLPCPAPNSRPA 80
AG + ++ A +S PA
Sbjct: 397 AGAQEPGETAASEAASSSLPA 417
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,462,672
Number of Sequences: 37866
Number of extensions: 1406705
Number of successful extensions: 6549
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 137
Number of HSP's that attempted gapping in prelim test: 6109
Number of HSP's gapped (non-prelim): 444
length of query: 936
length of database: 18,247,518
effective HSP length: 112
effective length of query: 824
effective length of database: 14,006,526
effective search space: 11541377424
effective search space used: 11541377424
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.