BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|35493782 ring finger protein 19 [Homo sapiens] (838 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|35493801 ring finger protein 19 [Homo sapiens] 1695 0.0 gi|35493782 ring finger protein 19 [Homo sapiens] 1695 0.0 gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 759 0.0 gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 722 0.0 gi|38045938 ring finger protein 144 [Homo sapiens] 108 3e-23 gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 101 3e-21 gi|50284696 IBR domain containing 2 [Homo sapiens] 99 1e-20 gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sa... 95 2e-19 gi|5453557 ariadne homolog 2 [Homo sapiens] 87 6e-17 gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 83 1e-15 gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 76 1e-13 gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 76 1e-13 gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 76 1e-13 gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 76 1e-13 gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 76 1e-13 gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 69 1e-11 gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 69 1e-11 gi|109150431 ring finger protein 31 [Homo sapiens] 62 3e-09 gi|169790973 parkin isoform 3 [Homo sapiens] 60 8e-09 gi|169790971 parkin isoform 2 [Homo sapiens] 60 8e-09 gi|169790969 parkin isoform 1 [Homo sapiens] 60 8e-09 gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 54 8e-07 gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 54 8e-07 gi|22749145 ring finger protein 217 [Homo sapiens] 50 7e-06 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 47 1e-04 gi|8923040 CDKN2A interacting protein [Homo sapiens] 42 0.003 gi|117938316 tripartite motif-containing 22 [Homo sapiens] 41 0.005 gi|22749455 ring finger protein 182 [Homo sapiens] 40 0.007 gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 40 0.009 gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 40 0.009 >gi|35493801 ring finger protein 19 [Homo sapiens] Length = 838 Score = 1695 bits (4390), Expect = 0.0 Identities = 838/838 (100%), Positives = 838/838 (100%) Query: 1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP 60 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP Sbjct: 1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP 60 Query: 61 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT 120 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT Sbjct: 61 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT 120 Query: 121 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT 180 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT Sbjct: 121 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT 180 Query: 181 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT 240 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT Sbjct: 181 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT 240 Query: 241 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP 300 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP Sbjct: 241 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP 300 Query: 301 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK 360 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK Sbjct: 301 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK 360 Query: 361 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV 420 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV Sbjct: 361 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV 420 Query: 421 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI 480 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI Sbjct: 421 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI 480 Query: 481 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA 540 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA Sbjct: 481 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA 540 Query: 541 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI 600 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI Sbjct: 541 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI 600 Query: 601 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA 660 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA Sbjct: 601 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA 660 Query: 661 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV 720 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV Sbjct: 661 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV 720 Query: 721 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV 780 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV Sbjct: 721 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV 780 Query: 781 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI 838 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI Sbjct: 781 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI 838 >gi|35493782 ring finger protein 19 [Homo sapiens] Length = 838 Score = 1695 bits (4390), Expect = 0.0 Identities = 838/838 (100%), Positives = 838/838 (100%) Query: 1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP 60 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP Sbjct: 1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP 60 Query: 61 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT 120 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT Sbjct: 61 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT 120 Query: 121 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT 180 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT Sbjct: 121 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT 180 Query: 181 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT 240 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT Sbjct: 181 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT 240 Query: 241 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP 300 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP Sbjct: 241 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP 300 Query: 301 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK 360 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK Sbjct: 301 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK 360 Query: 361 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV 420 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV Sbjct: 361 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV 420 Query: 421 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI 480 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI Sbjct: 421 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI 480 Query: 481 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA 540 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA Sbjct: 481 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA 540 Query: 541 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI 600 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI Sbjct: 541 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI 600 Query: 601 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA 660 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA Sbjct: 601 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA 660 Query: 661 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV 720 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV Sbjct: 661 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV 720 Query: 721 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV 780 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV Sbjct: 721 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV 780 Query: 781 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI 838 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI Sbjct: 781 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI 838 >gi|188219577 ring finger protein 19B isoform a [Homo sapiens] Length = 732 Score = 759 bits (1961), Expect = 0.0 Identities = 390/610 (63%), Positives = 451/610 (73%), Gaps = 24/610 (3%) Query: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIR 189 +ECPLCL+R +R P +++C HRSC DCLR YLR+EISESRV ISCPEC+ER NPHDIR Sbjct: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIR 176 Query: 190 LILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTE 249 L+L+D LM KYEEFMLRR+L +DPDCRWCPAPDCGYAVIA+GCASCPKLTC REGC TE Sbjct: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236 Query: 250 FCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYII 309 FCYHCKQIWHPNQTCD ARQ+RAQ+LR+RT +S +SY QESG A DDIKPCPRC+AYII Sbjct: 237 FCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPA-DDIKPCPRCSAYII 295 Query: 310 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLV 369 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTL+ Sbjct: 296 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLI 355 Query: 370 GAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPV 429 GAPVGI+LIAGIAIPAM+IGIPVYVGRKIH+RYEG+ SKHKRNLAI GGVTLSVI SPV Sbjct: 356 GAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPV 415 Query: 430 VAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAV 489 +AAV+VGIGVPIMLAYVYGVVPISLCR GGCGVS NGKGV+IEFD+++ G T Sbjct: 416 IAAVSVGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDD-----GPITVA 470 Query: 490 DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGS 549 D A NPSIGE S+ GLT LS SGS D + ++ SETAS AL+G +++G Sbjct: 471 DAW---RALKNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGG 527 Query: 550 LSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDK 609 + S ++RLEVQADVQKE + T SLG +SDNAST+AMAGSI++SY P D+ Sbjct: 528 ILSSGK-GKYSRLEVQADVQKEIF----PKDTASLGAISDNASTRAMAGSIISSYNPQDR 582 Query: 610 EGNSMEVQVDIESKPSKFRHNSGSSSVDD----GSATRSHAGGSSSGLPEGKSSATKWSK 665 E N+ME+QVDIE+KPS ++ SGSS+ D + GS G E S Sbjct: 583 ECNNMEIQVDIEAKPSHYQLVSGSSTEDSLHVHAQMAENEEEGSGGGGSEEDPPCRHQSC 642 Query: 666 EATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAP-SLSDSMPSV---- 720 E SK + I E DAQ + S E +P S + + PS Sbjct: 643 EQKDCLASKPWDISLAQPESIRSDLESSDAQSDDVPDITSDECGSPRSHTAACPSTPRAQ 702 Query: 721 -ADSHSSHFS 729 A S S+H + Sbjct: 703 GAPSPSAHMN 712 >gi|188219579 ring finger protein 19B isoform b [Homo sapiens] Length = 587 Score = 722 bits (1864), Expect = 0.0 Identities = 349/480 (72%), Positives = 396/480 (82%), Gaps = 15/480 (3%) Query: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIR 189 +ECPLCL+R +R P +++C HRSC DCLR YLR+EISESRV ISCPEC+ER NPHDIR Sbjct: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRVPISCPECSERLNPHDIR 176 Query: 190 LILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTE 249 L+L+D LM KYEEFMLRR+L +DPDCRWCPAPDCGYAVIA+GCASCPKLTC REGC TE Sbjct: 177 LLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCQTE 236 Query: 250 FCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYII 309 FCYHCKQIWHPNQTCD ARQ+RAQ+LR+RT +S +SY QESG DDIKPCPRC+AYII Sbjct: 237 FCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGP--DDIKPCPRCSAYII 294 Query: 310 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLV 369 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTL+ Sbjct: 295 KMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKILWQLGTLI 354 Query: 370 GAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGVTLSVIVSPV 429 GAPVGI+LIAGIAIPAM+IGIPVYVGRKIH+RYEG+ SKHKRNLAI GGVTLSVI SPV Sbjct: 355 GAPVGISLIAGIAIPAMVIGIPVYVGRKIHSRYEGRKTSKHKRNLAITGGVTLSVIASPV 414 Query: 430 VAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAV 489 +AAV+VGIGVPIMLAYVYGVVPISLCR GGCGVS NGKGV+IEFD+++ G T Sbjct: 415 IAAVSVGIGVPIMLAYVYGVVPISLCRGGGCGVSTANGKGVKIEFDEDD-----GPITVA 469 Query: 490 DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGS 549 D A NPSIGE S+ GLT LS SGS D + ++ SETAS AL+G +++G Sbjct: 470 DAW---RALKNPSIGESSIEGLTSVLSTSGSPTDGLSVMQGPYSETASFAALSGGTLSGG 526 Query: 550 LSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDK 609 + S ++RLEVQADVQKE + T SLG +SDNAST+AMAGSI++SY P D+ Sbjct: 527 ILSSGK-GKYSRLEVQADVQKEIF----PKDTASLGAISDNASTRAMAGSIISSYNPQDR 581 >gi|38045938 ring finger protein 144 [Homo sapiens] Length = 292 Score = 108 bits (269), Expect = 3e-23 Identities = 76/274 (27%), Positives = 121/274 (44%), Gaps = 30/274 (10%) Query: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISES-RVNISCPE--CTER--FN 184 + C LCL + ++ I C C CL+QY+ + I E ISCP+ C ++ Sbjct: 18 VSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHLQ 77 Query: 185 PHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAF---GCASCPKLTC 241 ++I +++ ++ M++Y++ R ++ DP WCPA C AV G + + C Sbjct: 78 ENEIECMVAAEI-MQRYKKLQFEREVLFDPCRTWCPASTC-QAVCQLQDVGLQTPQPVQC 135 Query: 242 GREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPC 301 + C EFC CK WHP Q C + +S+ +E A IK C Sbjct: 136 --KACRMEFCSTCKASWHPGQGC-----PETMPITFLPGETSAAFKMEEDDA---PIKRC 185 Query: 302 PRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD----LHYLSPSGCTFWGKKPWSR 357 P+C YI + D C M C C FCW C++ + D +HY C K Sbjct: 186 PKCKVYIER--DEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHY-DKGPCR---NKLGHS 239 Query: 358 KKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIP 391 + ++W +VG G L+ +A P +++ P Sbjct: 240 RASVIWHRTQVVGIFAGFGLLLLVASPFLLLATP 273 >gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 [Homo sapiens] Length = 557 Score = 101 bits (251), Expect = 3e-21 Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 23/208 (11%) Query: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN--ISCPE--CTERFNPHD 187 C +C L + F + C H+ C+ C +YL +I E + ISCP C + + Sbjct: 186 CQICYLNYPNSYFTGL-ECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNT 244 Query: 188 IRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCG 247 + +++D + KY+ + ++ + +WCPAPDC + V P R CG Sbjct: 245 VMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVV----KVQYPDAKPVRCKCG 300 Query: 248 TEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAY 307 +FC++C + WH C L+ S+ S A + K CP+C Sbjct: 301 RQFCFNCGENWHDPVKCK----------WLKKWIKKCDDDSETSNWIAANTKECPKCHVT 350 Query: 308 IIKMNDGSCNHMTC--AVCGCEFCWLCM 333 I K DG CNHM C C EFCW+C+ Sbjct: 351 IEK--DGGCNHMVCRNQNCKAEFCWVCL 376 >gi|50284696 IBR domain containing 2 [Homo sapiens] Length = 303 Score = 99.4 bits (246), Expect = 1e-20 Identities = 71/273 (26%), Positives = 111/273 (40%), Gaps = 24/273 (8%) Query: 130 IECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTER--FN 184 I C LCL S D+ + C C CL+QY+++ I E + I+CP+ C Sbjct: 28 ITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQ 87 Query: 185 PHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGRE 244 +I ++ D + Y+ R + DP WCP DC + Sbjct: 88 EAEIACLVPVD-QFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECP 146 Query: 245 GCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRC 304 C +FC CK WH +C +Q + L T + E+ IK CP C Sbjct: 147 SCHLKFCSCCKDAWHAEVSC-----RDSQPIVLPTEHRALFGTDAEA-----PIKQCPVC 196 Query: 305 AAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISD---LHYLSPSGCTFWGKKPWSRKKKI 361 Y I+ N+G C M C C FCW C++ + + L + C K + + Sbjct: 197 RVY-IERNEG-CAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCR---NKLGHSRASV 251 Query: 362 LWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYV 394 +W +VG VG+ +IA + P +++ P + Sbjct: 252 MWNRTQVVGILVGLGIIALVTSPLLLLASPCII 284 >gi|148596953 ankyrin repeat and IBR domain containing 1 [Homo sapiens] Length = 1089 Score = 95.1 bits (235), Expect = 2e-19 Identities = 69/248 (27%), Positives = 107/248 (43%), Gaps = 29/248 (11%) Query: 111 TNTSSDNGLTSISKQIGDFIE--CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEIS 168 T SS IS GD C +C+ S P M C H C C +L ++I Sbjct: 310 TTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQ 369 Query: 169 ESRV-NISCP--ECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCG 225 E NI CP +C + I ++S + + ++Y +F ++ ++ +P +WCP P C Sbjct: 370 EGEAHNIFCPAYDCFQLVPVDIIESVVSKE-MDKRYLQFDIKAFVENNPAIKWCPTPGCD 428 Query: 226 YAV--------------IAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQER 271 AV ++F P + CG+ G FC+ C H C + Sbjct: 429 RAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGK---GHLFCWECLGEAHEPCDCQTWKNWL 485 Query: 272 AQSLRLRTIRSSSISYSQESGAAA----DDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCE 327 + ++ +S + E A + KPC C + I K N+G CNHM CA C + Sbjct: 486 QKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQK-NEG-CNHMQCAKCKYD 543 Query: 328 FCWLCMKE 335 FCW+C++E Sbjct: 544 FCWICLEE 551 >gi|5453557 ariadne homolog 2 [Homo sapiens] Length = 493 Score = 87.0 bits (214), Expect = 6e-17 Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 19/205 (9%) Query: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISES-RVNISC--PECTERFNPHDI 188 C +C+ K+ + C H+ C C Q+ + + + V +SC +C R + Sbjct: 139 CAVCMQFVRKENLLSL-ACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFV 197 Query: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248 +L ++ L EKY ++ R ++ + + CP DC VI ++ C R C Sbjct: 198 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPM-VIRVQEPRARRVQCNR--CNE 254 Query: 249 EFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYI 308 FC+ C+Q++H C +R + S+ + + K CP+C I Sbjct: 255 VFCFKCRQMYHAPTDCAT----------IRKWLTKCADDSETANYISAHTKDCPKCNICI 304 Query: 309 IKMNDGSCNHMTCAVCGCEFCWLCM 333 K +G CNHM C+ C +FCW+C+ Sbjct: 305 EK--NGGCNHMQCSKCKHDFCWMCL 327 >gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo sapiens] Length = 2517 Score = 82.8 bits (203), Expect = 1e-15 Identities = 63/215 (29%), Positives = 93/215 (43%), Gaps = 17/215 (7%) Query: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRV-NISCP--ECTERFNPHDI 188 CP+C+ D + C H C C +YL I ++ V N +CP +C + I Sbjct: 2070 CPVCVSPLGCDDDLPSLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFI 2129 Query: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIA---FGCASCPKLTCGREG 245 R I+S ++ KYE+ +LR ++ + + WC P ++ GC + TC + Sbjct: 2130 RAIVSSPEVISKYEKALLRGYVESCSNLTWCTNPQGCDRILCRQGLGCGT----TCSK-- 2183 Query: 246 CGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKPCPRCA 305 CG C++C P A+ +Q + +Q A K CP C Sbjct: 2184 CGWASCFNCS---FPEAHYPASCGHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQ 2240 Query: 306 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH 340 A I K N+G C HMTCA C FCW C+K H Sbjct: 2241 APIEK-NEG-CLHMTCAKCNHGFCWRCLKSWKPNH 2273 >gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 76.3 bits (186), Expect = 1e-13 Identities = 54/226 (23%), Positives = 86/226 (38%), Gaps = 27/226 (11%) Query: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTERFNPHDI 188 C +C + C H C CL+ Y I+I + +V ++CPE C P + Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279 Query: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248 + ++ + L +Y+ +L+ L D +CP P C V+ C C C Sbjct: 280 KELVEAE-LFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 334 Query: 249 EFCYHCKQIWHPNQTC-----------------DAARQERAQSLRLRTIRSSSISYSQES 291 FC C+ +H C D A + + + ++ + Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394 Query: 292 GAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 337 + K CP C I K++ CN MTC C FCW+CM +S Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438 >gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 76.3 bits (186), Expect = 1e-13 Identities = 54/226 (23%), Positives = 86/226 (38%), Gaps = 27/226 (11%) Query: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTERFNPHDI 188 C +C + C H C CL+ Y I+I + +V ++CPE C P + Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279 Query: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248 + ++ + L +Y+ +L+ L D +CP P C V+ C C C Sbjct: 280 KELVEAE-LFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 334 Query: 249 EFCYHCKQIWHPNQTC-----------------DAARQERAQSLRLRTIRSSSISYSQES 291 FC C+ +H C D A + + + ++ + Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394 Query: 292 GAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 337 + K CP C I K++ CN MTC C FCW+CM +S Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438 >gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 76.3 bits (186), Expect = 1e-13 Identities = 54/226 (23%), Positives = 86/226 (38%), Gaps = 27/226 (11%) Query: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTERFNPHDI 188 C +C + C H C CL+ Y I+I + +V ++CPE C P + Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279 Query: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248 + ++ + L +Y+ +L+ L D +CP P C V+ C C C Sbjct: 280 KELVEAE-LFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 334 Query: 249 EFCYHCKQIWHPNQTC-----------------DAARQERAQSLRLRTIRSSSISYSQES 291 FC C+ +H C D A + + + ++ + Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394 Query: 292 GAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 337 + K CP C I K++ CN MTC C FCW+CM +S Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438 >gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] Length = 348 Score = 76.3 bits (186), Expect = 1e-13 Identities = 54/226 (23%), Positives = 86/226 (38%), Gaps = 27/226 (11%) Query: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTERFNPHDI 188 C +C + C H C CL+ Y I+I + +V ++CPE C P + Sbjct: 94 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 153 Query: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248 + ++ + L +Y+ +L+ L D +CP P C V+ C C C Sbjct: 154 KELVEAE-LFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 208 Query: 249 EFCYHCKQIWHPNQTC-----------------DAARQERAQSLRLRTIRSSSISYSQES 291 FC C+ +H C D A + + + ++ + Sbjct: 209 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 268 Query: 292 GAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 337 + K CP C I K++ CN MTC C FCW+CM +S Sbjct: 269 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 312 >gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] Length = 474 Score = 76.3 bits (186), Expect = 1e-13 Identities = 54/226 (23%), Positives = 86/226 (38%), Gaps = 27/226 (11%) Query: 132 CPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVN-ISCPE--CTERFNPHDI 188 C +C + C H C CL+ Y I+I + +V ++CPE C P + Sbjct: 220 CSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQV 279 Query: 189 RLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGT 248 + ++ + L +Y+ +L+ L D +CP P C V+ C C C Sbjct: 280 KELVEAE-LFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQE--PGCTMGICS--SCNF 334 Query: 249 EFCYHCKQIWHPNQTC-----------------DAARQERAQSLRLRTIRSSSISYSQES 291 FC C+ +H C D A + + + ++ + Sbjct: 335 AFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESK 394 Query: 292 GAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEIS 337 + K CP C I K++ CN MTC C FCW+CM +S Sbjct: 395 EWLEKNSKSCPCCGTPIEKLD--GCNKMTCTGCMQYFCWICMGSLS 438 >gi|46370057 ring finger protein 216 isoform b [Homo sapiens] Length = 866 Score = 69.3 bits (168), Expect = 1e-11 Identities = 62/243 (25%), Positives = 98/243 (40%), Gaps = 38/243 (15%) Query: 127 GDFIECPLCLLRHSKDRFPDIMTCH--HRSCVDCLRQYLRIEISES-RVNISCPE--CTE 181 G IEC C + + F ++ C H C +CL +Y + + S ++ +SC E CT Sbjct: 510 GQLIECRCC---YGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTC 566 Query: 182 RFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTC 241 F ++ +L +L + YE A D P C + + + + +C Sbjct: 567 SFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD-ELVRCPSCSFPALLD--SDVKRFSC 623 Query: 242 GREGCGTEFCYHCKQIW--HPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIK 299 C E C C+ +W H TC+ ++ ++ RT S E A I+ Sbjct: 624 PNPHCRKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT--------SIEEKMTAARIR 673 Query: 300 PCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGC 347 C +C +IK CN M+C CG + C+LC I+ H SP S C Sbjct: 674 KCHKCGTGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRC 730 Query: 348 TFW 350 + W Sbjct: 731 SLW 733 >gi|46358403 ring finger protein 216 isoform a [Homo sapiens] Length = 923 Score = 69.3 bits (168), Expect = 1e-11 Identities = 62/243 (25%), Positives = 98/243 (40%), Gaps = 38/243 (15%) Query: 127 GDFIECPLCLLRHSKDRFPDIMTCH--HRSCVDCLRQYLRIEISES-RVNISCPE--CTE 181 G IEC C + + F ++ C H C +CL +Y + + S ++ +SC E CT Sbjct: 567 GQLIECRCC---YGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTC 623 Query: 182 RFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTC 241 F ++ +L +L + YE A D P C + + + + +C Sbjct: 624 SFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD-ELVRCPSCSFPALLD--SDVKRFSC 680 Query: 242 GREGCGTEFCYHCKQIW--HPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIK 299 C E C C+ +W H TC+ ++ ++ RT S E A I+ Sbjct: 681 PNPHCRKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT--------SIEEKMTAARIR 730 Query: 300 PCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGC 347 C +C +IK CN M+C CG + C+LC I+ H SP S C Sbjct: 731 KCHKCGTGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRC 787 Query: 348 TFW 350 + W Sbjct: 788 SLW 790 >gi|109150431 ring finger protein 31 [Homo sapiens] Length = 1072 Score = 61.6 bits (148), Expect = 3e-09 Identities = 67/293 (22%), Positives = 106/293 (36%), Gaps = 67/293 (22%) Query: 131 ECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRV-NISCPECTERFNPHDIR 189 EC +C +R + +C C DC RQ+ I + E + ++ CP C D + Sbjct: 698 ECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQ 757 Query: 190 LI---------LSDDVLMEKYEEF---MLRRWLVADPDCRWCPAPDCGYAVIAFGC-ASC 236 L+ L + + + Y F + L+ DP WC G+ A+C Sbjct: 758 LLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQCSFGFIYEREQLEATC 817 Query: 237 PKLTCGREGCGTEFCYHCKQIW---HPNQTCDAAR--------QERAQSLRLRTIRSSSI 285 P+ C FC CK+ W H ++C+ + + +AQ L + Sbjct: 818 PQ-------CHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAM-------- 862 Query: 286 SYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEI--------- 336 Y QE+G CP+C + + G C H C C +FC C Sbjct: 863 -YLQENGI------DCPKC-KFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEP 914 Query: 337 -----SDLHYLSPSGCTFWGKKPWS--RKKKILWQLGTLVGA--PVGIALIAG 380 LH P C F+ + W+ R +K+L + P G + G Sbjct: 915 NCRVKKSLHGHHPRDCLFY-LRDWTALRLQKLLQDNNVMFNTEPPAGARAVPG 966 >gi|169790973 parkin isoform 3 [Homo sapiens] Length = 316 Score = 60.1 bits (144), Expect = 8e-09 Identities = 37/123 (30%), Positives = 55/123 (44%), Gaps = 14/123 (11%) Query: 219 CPAPDCGYAVIAFGCASCPKLTC---GREGCGTEFCYHCKQIWHPNQTCDAARQERAQSL 275 CP P CG ++ K+TC GCG FC CK+ +H + C A + + Sbjct: 183 CPRPGCGAGLLPE--PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGE-CSAVFEASGTTT 239 Query: 276 RLRTIRSSSISYSQESGAAADDI----KPCPRCAAYIIKMNDGSCNHMTC--AVCGCEFC 329 + + + ++ A+ + I KPCPRC + K +G C HM C C E+C Sbjct: 240 QAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEK--NGGCMHMKCPQPQCRLEWC 297 Query: 330 WLC 332 W C Sbjct: 298 WNC 300 >gi|169790971 parkin isoform 2 [Homo sapiens] Length = 437 Score = 60.1 bits (144), Expect = 8e-09 Identities = 37/123 (30%), Positives = 55/123 (44%), Gaps = 14/123 (11%) Query: 219 CPAPDCGYAVIAFGCASCPKLTC---GREGCGTEFCYHCKQIWHPNQTCDAARQERAQSL 275 CP P CG ++ K+TC GCG FC CK+ +H + C A + + Sbjct: 304 CPRPGCGAGLLPE--PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGE-CSAVFEASGTTT 360 Query: 276 RLRTIRSSSISYSQESGAAADDI----KPCPRCAAYIIKMNDGSCNHMTC--AVCGCEFC 329 + + + ++ A+ + I KPCPRC + K +G C HM C C E+C Sbjct: 361 QAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEK--NGGCMHMKCPQPQCRLEWC 418 Query: 330 WLC 332 W C Sbjct: 419 WNC 421 >gi|169790969 parkin isoform 1 [Homo sapiens] Length = 465 Score = 60.1 bits (144), Expect = 8e-09 Identities = 37/123 (30%), Positives = 55/123 (44%), Gaps = 14/123 (11%) Query: 219 CPAPDCGYAVIAFGCASCPKLTC---GREGCGTEFCYHCKQIWHPNQTCDAARQERAQSL 275 CP P CG ++ K+TC GCG FC CK+ +H + C A + + Sbjct: 332 CPRPGCGAGLLPE--PDQRKVTCEGGNGLGCGFAFCRECKEAYHEGE-CSAVFEASGTTT 388 Query: 276 RLRTIRSSSISYSQESGAAADDI----KPCPRCAAYIIKMNDGSCNHMTC--AVCGCEFC 329 + + + ++ A+ + I KPCPRC + K +G C HM C C E+C Sbjct: 389 QAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEK--NGGCMHMKCPQPQCRLEWC 446 Query: 330 WLC 332 W C Sbjct: 447 WNC 449 >gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 isoform 1 [Homo sapiens] Length = 468 Score = 53.5 bits (127), Expect = 8e-07 Identities = 53/222 (23%), Positives = 87/222 (39%), Gaps = 48/222 (21%) Query: 131 ECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCP------ECTERFN 184 ECP+C + + C H C +CL+ +R + +SCP C+ + Sbjct: 239 ECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLL 295 Query: 185 PHDIRLILSDDVLMEKYEEFMLRRWLVAD-----------PDCR-WCPAPDCGYAVIAFG 232 +I+ +L+ E Y+ F+ +A+ PDC+ WC D V F Sbjct: 296 EREIKALLTP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFT 348 Query: 233 CASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQE---RAQSLRLRTIRSSSISYSQ 289 C C + C CK I H C +++ RAQ+ + + Sbjct: 349 CPVCFHVNC----------LLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVML 397 Query: 290 ESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWL 331 + G A CP+C +++ DG C+ + C VC E CW+ Sbjct: 398 QQGEAMR----CPQCQI-VVQKKDG-CDWIRCTVCHTEICWV 433 >gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 isoform 2 [Homo sapiens] Length = 510 Score = 53.5 bits (127), Expect = 8e-07 Identities = 53/222 (23%), Positives = 87/222 (39%), Gaps = 48/222 (21%) Query: 131 ECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCP------ECTERFN 184 ECP+C + + C H C +CL+ +R + +SCP C+ + Sbjct: 281 ECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIR---NSQEAEVSCPFIDNTYSCSGKLL 337 Query: 185 PHDIRLILSDDVLMEKYEEFMLRRWLVAD-----------PDCR-WCPAPDCGYAVIAFG 232 +I+ +L+ E Y+ F+ +A+ PDC+ WC D V F Sbjct: 338 EREIKALLTP----EDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFED---DVNEFT 390 Query: 233 CASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQE---RAQSLRLRTIRSSSISYSQ 289 C C + C CK I H C +++ RAQ+ + + Sbjct: 391 CPVCFHVNC----------LLCKAI-HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVML 439 Query: 290 ESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWL 331 + G A CP+C +++ DG C+ + C VC E CW+ Sbjct: 440 QQGEAMR----CPQCQI-VVQKKDG-CDWIRCTVCHTEICWV 475 >gi|22749145 ring finger protein 217 [Homo sapiens] Length = 275 Score = 50.4 bits (119), Expect = 7e-06 Identities = 48/203 (23%), Positives = 79/203 (38%), Gaps = 37/203 (18%) Query: 165 IEISESRVNISCP--ECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAP 222 +++ +V I CP EC E + L+ + + KY+ F+ + D P P Sbjct: 1 MKVQLGQVEIKCPITECFEFLEETTVVYNLTHEDSI-KYKYFLE----LGRIDSSTKPCP 55 Query: 223 DC---------GYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQ 273 C G+ S K+ C C +C+ C WH C +E + Sbjct: 56 QCKHFTTFKKKGHIPTPSRSESKYKIQCPT--CQFVWCFKCHSPWHEGVNC----KEYKK 109 Query: 274 SLRLRTIRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCM 333 +L +S I + Q + + CP+C +I + C+HMTC+ C FC+ C Sbjct: 110 GDKLLRHWASEIEHGQRNA------QKCPKCKIHIQRTE--GCDHMTCSQCNTNFCYRCG 161 Query: 334 KEISDLHY-------LSPSGCTF 349 + L + LS GC + Sbjct: 162 ERYRQLRFFGDHTSNLSIFGCKY 184 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 46.6 bits (109), Expect = 1e-04 Identities = 67/319 (21%), Positives = 120/319 (37%), Gaps = 11/319 (3%) Query: 475 DDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSE 534 D N N ++ + D++ + + + + + S + + S S D D+ S Sbjct: 658 DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS----SDSDSS 713 Query: 535 TASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTK 594 +S + + +S + S + S + N + S S +S S + S ++S Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773 Query: 595 AMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSS-SVDDGSATRSHAGGSSSGL 653 + + NS D +S S S +S SS S D S+ S + SS Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833 Query: 654 PEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSL 713 SS + S +++ G S S N +++ + D+ S +S E+ + Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS--SDSSDSSDSSNSSDSSDSSDSNESSNS 891 Query: 714 SDSMPSV----ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLE 769 SDS S +DS S S S S +S S SSD + N ++ Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951 Query: 770 NSPHQCSISVVTQTASCSE 788 NS + S + ++ S+ Sbjct: 952 NSSDSSNSSDSSNSSDSSD 970 Score = 44.3 bits (103), Expect = 5e-04 Identities = 60/280 (21%), Positives = 106/280 (37%), Gaps = 7/280 (2%) Query: 476 DENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSET 535 D +D + +N++ D+ S + S + S + S S D + + S++ Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624 Query: 536 ASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVS------LGTVSD 589 S+ + + +S + S S S+ N + + S S +S S + S Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684 Query: 590 NASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGS 649 N+S + + NS D +S D + +S SS+ D S + + + S Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744 Query: 650 SSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFE 709 S S ++ S + + S S + + D S+NSS+ Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804 Query: 710 APSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 S S +DS SS+ S+ S S +S +S S SSD Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSS-DSSDSSNSSDSSD 843 Score = 43.9 bits (102), Expect = 6e-04 Identities = 70/358 (19%), Positives = 144/358 (40%), Gaps = 23/358 (6%) Query: 476 DENDINVGGTNTAV----DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDN 531 DE+ N G+++ D+ S ++ ++ S G G+ G S SG D+ Sbjct: 496 DESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS------DS 549 Query: 532 LSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNA 591 +S + + S S S S+ N + + +D S S S + + SD++ Sbjct: 550 SDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD-SSDSDSSDSSDSDSSDSSNSSDSSDSS 608 Query: 592 STKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSS 651 + + S +S D + + D +SK NS SS + S+ S++ SS Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSS-DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD 667 Query: 652 GLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAP 711 SS + S +++ S + +E+ + D S++S ++ Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSS----DSSNSSESSDSSD-------SSDSDSSDSS 716 Query: 712 SLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENS 771 S+S S +DS +S S S + +S +S S SSD + N ++ +S Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776 Query: 772 PHQCSISVVTQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTME 829 + S +++ S+ S ++ ++ ++ + D D+ +++++S + + Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834 Score = 42.4 bits (98), Expect = 0.002 Identities = 63/294 (21%), Positives = 110/294 (37%), Gaps = 20/294 (6%) Query: 465 GNGKGVRIEFDDENDINV--------GGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLS 516 GNG + DD++D G N D +++ S S + + S Sbjct: 502 GNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSS 561 Query: 517 ASGSHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLS 576 S D + ++ S++ S+ + + S S S+ N + + S S Sbjct: 562 DSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS--NSSDSSDSSDSSDSSDSSDS 619 Query: 577 GESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSS- 635 +S + S + SD++ + + + S + NS + + +S S NS SS Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDS---------SDSNSSDSSDNSDSSDSSNSSNSSDSSD 670 Query: 636 VDDGSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDA 695 D S + S + S+S S ++ S+ + + S S + N + D Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730 Query: 696 QLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 S+NSS+ S S + +DS S S S +S +S S SSD Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784 Score = 41.6 bits (96), Expect = 0.003 Identities = 57/274 (20%), Positives = 105/274 (38%), Gaps = 18/274 (6%) Query: 476 DENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSET 535 D +D N ++ D++ + + ++ + S + S S S + D + + S Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSE 700 Query: 536 ASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKA 595 +S + + S + S S+ N +D S S +S S + S ++S + Sbjct: 701 SSDSSDSSDSDSSDSSDSSNSN-------SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753 Query: 596 MAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPE 655 + +S NS + +S S NS S+ S+ S + SS Sbjct: 754 DSSDSSDS-------SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806 Query: 656 GKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSD 715 SS + S ++ + S S + + D S +S+ ++ + SD Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866 Query: 716 SMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 S S S+SS S+ S +S ++S S SSD Sbjct: 867 SSDSSDSSNSSDSSDSS----DSNESSNSSDSSD 896 Score = 40.0 bits (92), Expect = 0.009 Identities = 55/281 (19%), Positives = 105/281 (37%), Gaps = 9/281 (3%) Query: 476 DENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSET 535 D +D + ++ + ++ S N S S S S+ S+ D+ + + Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765 Query: 536 ASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKA 595 S+ + + + S + S + N + S S +S S + SD++++ Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825 Query: 596 MAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPE 655 + S +S +S + + S + S SS+ D S + + S S Sbjct: 826 SSNSSDSS--DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883 Query: 656 GKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSD 715 + ++ S + + S S + +++ D+ S NS+ ++ + SD Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943 Query: 716 SMPSVADSHSSHFSEFS-------CSDLESMKTSCSHGSSD 749 S S S+SS S S SD S +S S SSD Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984 Score = 40.0 bits (92), Expect = 0.009 Identities = 56/274 (20%), Positives = 108/274 (39%), Gaps = 11/274 (4%) Query: 476 DENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSET 535 D +D N ++ D++ + + + S + + S ++S S + N S++ Sbjct: 881 DSSDSNESSNSS--DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938 Query: 536 ASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKA 595 +++ + +S + + S S+ + + +D S S S S + S ++S + Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998 Query: 596 MAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPE 655 + + +S D +S S S +S SS D S + + S S Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058 Query: 656 GKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSD 715 S ++ S + + S S +E+ + D+ S +S ++ SD Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSS--------DSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110 Query: 716 SMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 S S S SS+ S+ S S +S +S S SSD Sbjct: 1111 SSDSSDSSDSSNSSDSSDSS-DSSDSSDSSNSSD 1143 Score = 39.7 bits (91), Expect = 0.012 Identities = 53/275 (19%), Positives = 99/275 (36%), Gaps = 2/275 (0%) Query: 475 DDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSE 534 D N + ++ + D ++ +++ ++ + S + S S + + N S+ Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975 Query: 535 TASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTK 594 ++ + + +S + S S+ + + +D S S S S + S N+S Sbjct: 976 SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS--SDSSNSSDSSNSSDSSNSSDS 1033 Query: 595 AMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLP 654 + + +S D +S S S +S SS D S + + S S Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093 Query: 655 EGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLS 714 S ++ S + + S S N + D S++SS+ S S Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153 Query: 715 DSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 +DS S S S +S +S S SSD Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188 Score = 39.3 bits (90), Expect = 0.015 Identities = 53/265 (20%), Positives = 96/265 (36%), Gaps = 6/265 (2%) Query: 490 DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGS 549 D++ ++++ + S E +S S+ D+ + S+ + + + S Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS 674 Query: 550 LSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDK 609 S+ + N + S S +S S SD++ + S +S D Sbjct: 675 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734 Query: 610 EGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSATKWSKEATA 669 +S S S +S SS + S + + S S S + S + + Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794 Query: 670 GKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV-----ADSH 724 S S + + D D+ S +S ++ + SDS S +DS Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854 Query: 725 SSHFSEFSCSDLESMKTSCSHGSSD 749 SS+ S+ S S +S +S S SSD Sbjct: 855 SSNRSDSSNSS-DSSDSSDSSNSSD 878 Score = 38.9 bits (89), Expect = 0.020 Identities = 53/274 (19%), Positives = 108/274 (39%), Gaps = 8/274 (2%) Query: 476 DENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSET 535 D + + ++ + D+++ +++ + + + S + + S S D N S++ Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS-----SNSSDS 956 Query: 536 ASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKA 595 +++ + +S + + S + N + S S +S S + S ++S + Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016 Query: 596 MAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPE 655 + NS + +S S S +S SS+ D S + + S S Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076 Query: 656 GKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSD 715 S +++ S + + S S + +++ + D+ S +S ++ SD Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134 Query: 716 SMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 S S S SS SE S S +S +S S SSD Sbjct: 1135 SSDSSNSSDSSDSSESSDSS-DSSDSSDSSDSSD 1167 Score = 38.9 bits (89), Expect = 0.020 Identities = 54/275 (19%), Positives = 101/275 (36%), Gaps = 7/275 (2%) Query: 475 DDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSE 534 D N + ++ + D++ +++ ++ + S + + S S + D N S+ Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS-----SNSSD 1032 Query: 535 TASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTK 594 ++ + + +S + S S+ + N + S S +S S + S ++S Sbjct: 1033 SSDSSDSSDSSDSSDSSDSS--DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090 Query: 595 AMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLP 654 + + +S D +S S S +S SS D S + + + S S Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150 Query: 655 EGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLS 714 S ++ S + + S S N + D S++SS+ S S Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1210 Query: 715 DSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 +DS S S S ES +S S SSD Sbjct: 1211 SDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245 Score = 38.5 bits (88), Expect = 0.026 Identities = 52/275 (18%), Positives = 100/275 (36%) Query: 475 DDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSE 534 + N + ++ + D+ S + + S + + S ++S + + + S+ Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946 Query: 535 TASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTK 594 ++ + + +S + S S+ + N + S S +S S + S N+S Sbjct: 947 SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006 Query: 595 AMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLP 654 + + +S D +S S S +S SS D S + + + S S Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066 Query: 655 EGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLS 714 S ++ S + + + S S + + D S++SS+ S S Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126 Query: 715 DSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 +DS S S S ES +S S SSD Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161 Score = 38.1 bits (87), Expect = 0.034 Identities = 48/265 (18%), Positives = 98/265 (36%) Query: 485 TNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGA 544 ++ + D++ +++ + + + S + +S S + N S+++ + + Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932 Query: 545 SITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSILNSY 604 S + S S+ + + +D S + + S + S ++S + + +S Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992 Query: 605 IPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSATKWS 664 D +S S S ++S SS+ D S + + S S S ++ S Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052 Query: 665 KEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSVADSH 724 + + S S + + D S+NSS+ S S +DS Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112 Query: 725 SSHFSEFSCSDLESMKTSCSHGSSD 749 S S S + +S +S S SSD Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSD 1137 Score = 37.4 bits (85), Expect = 0.058 Identities = 51/277 (18%), Positives = 110/277 (39%), Gaps = 4/277 (1%) Query: 475 DDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSE 534 D N + ++ + D++ + + + + + + S S + D + N S+ Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913 Query: 535 TASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTK 594 ++ + + +S + + S ++ + + +D S S S + SD++ + Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS-SDSSNSSDSSNSSDSSDSN 972 Query: 595 AMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLP 654 + S ++ +S + +S S +S SS S+ S++ SS+ Sbjct: 973 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032 Query: 655 EGKSSATKWSKEATAGKKSK--SGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPS 712 SS + S +++ S S + +++ + D+ S +S ++ + Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092 Query: 713 LSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 SDS S S SS S+ S S +S +S S SSD Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDSSD 1128 Score = 35.4 bits (80), Expect = 0.22 Identities = 39/176 (22%), Positives = 63/176 (35%) Query: 574 SLSGESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGS 633 S S +S S + S ++S + + +S D +S S S +S S Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 1141 Query: 634 SSVDDGSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDM 693 S D S + + S S S ++ S + + S S + + D Sbjct: 1142 SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201 Query: 694 DAQLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 S++SS+ S S +DS+ S S S +S +S S SSD Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257 Score = 34.7 bits (78), Expect = 0.38 Identities = 39/174 (22%), Positives = 63/174 (36%) Query: 576 SGESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSS 635 S ES S + S ++S + + +S D +S S S +S SS+ Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140 Query: 636 VDDGSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDA 695 D S + + S S S ++ S + + S S + + D Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200 Query: 696 QLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 S++SS+ S S +DS S+ S S +S +S S SSD Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254 Score = 34.7 bits (78), Expect = 0.38 Identities = 40/183 (21%), Positives = 70/183 (38%), Gaps = 17/183 (9%) Query: 576 SGESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSS 635 S +S S + S N+S + + +S D +S S S ++S SS Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185 Query: 636 VDDGSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDA 695 D S + + S S S ++ S + + S S +++ E D+ Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS--------SDSNESSDS 1237 Query: 696 QLLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEF---------SCSDLESMKTSCSHG 746 S +S+ ++ SDS S +DS+ S+ S SD +S + +H Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297 Query: 747 SSD 749 +SD Sbjct: 1298 TSD 1300 Score = 34.3 bits (77), Expect = 0.49 Identities = 52/275 (18%), Positives = 100/275 (36%), Gaps = 9/275 (3%) Query: 475 DDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSE 534 D N + ++ + D+++ +++ ++ S + S S D D+ Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDS----SDSSDS 1054 Query: 535 TASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTK 594 + S+ + + + S S + + E S S +S S + S ++S Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114 Query: 595 AMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLP 654 + + NS D +S S S +S SS D S + + S S Sbjct: 1115 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174 Query: 655 EGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLS 714 S+++ S + + S S + +++ + D+ S +S ++ S Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSD-----SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229 Query: 715 DSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 DS S S SS S+ S S S + S +SD Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSD 1264 Score = 32.3 bits (72), Expect = 1.9 Identities = 40/157 (25%), Positives = 65/157 (41%), Gaps = 6/157 (3%) Query: 598 GSILNS--YIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAG-GSSSGLP 654 GS NS Y D + SM+ D S ++ +S D+ S++R A S Sbjct: 442 GSDSNSDGYDSYDFDDKSMQGD-DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKD 500 Query: 655 EGKSSATKWSKEATAGKKSKSGKLRKKGNMKI-NETREDMDAQLLEQQSTNSSEFEAPSL 713 G S +K +++ + S + GN N+ + D+ + S++S ++ + Sbjct: 501 NGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNS 560 Query: 714 SDSMPSV-ADSHSSHFSEFSCSDLESMKTSCSHGSSD 749 SDS S +DS S+ S S S S SSD Sbjct: 561 SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD 597 Score = 30.8 bits (68), Expect = 5.5 Identities = 21/87 (24%), Positives = 37/87 (42%) Query: 621 ESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRK 680 +S S +S SS + S+ S + SS SS + S ++T+ +S K Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274 Query: 681 KGNMKINETREDMDAQLLEQQSTNSSE 707 GN N + D D++ + + S + Sbjct: 1275 SGNGNNNGSDSDSDSEGSDSNHSTSDD 1301 >gi|8923040 CDKN2A interacting protein [Homo sapiens] Length = 580 Score = 41.6 bits (96), Expect = 0.003 Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 16/172 (9%) Query: 578 ESGTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDI-ESKPSKFRHNSGSSSV 636 +SG+ + ++++ + + S + +PL S EV++ + SKPS +SG + Sbjct: 265 QSGSPKKSALEGSSASASQSSSEIE--VPLLGSSGSSEVELPLLSSKPSSETASSGLT-- 320 Query: 637 DDGSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQ 696 S T S A SSS SS T ++ + S + +++ + A Sbjct: 321 ---SKTSSEASVSSSVAKNSSSSGTSLLTPKSSSSTNTS--------LLTSKSTSQVAAS 369 Query: 697 LLEQQSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSS 748 LL +S++ + S S S+ SV+ S S+ S S L S TS S SS Sbjct: 370 LLASKSSSQTSGSLVSKSTSLASVSQLASKSSSQTSTSQLPSKSTSQSSESS 421 >gi|117938316 tripartite motif-containing 22 [Homo sapiens] Length = 498 Score = 40.8 bits (94), Expect = 0.005 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 3/69 (4%) Query: 121 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT 180 S+ I + CP+CL ++ P + C H C C+ ++ + SR SCP C Sbjct: 4 SVKVDIEKEVTCPICLELLTE---PLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60 Query: 181 ERFNPHDIR 189 RF P ++R Sbjct: 61 TRFQPGNLR 69 >gi|22749455 ring finger protein 182 [Homo sapiens] Length = 247 Score = 40.4 bits (93), Expect = 0.007 Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 3/73 (4%) Query: 125 QIGDFIECPLCLLRHS-KDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT-ER 182 Q D +EC +C R++ K R P ++ C HR C CL + + S V I CP C E Sbjct: 13 QASDELECKICYNRYNLKQRKPKVLECCHRVCAKCLYKIIDFGDSPQGV-IVCPFCRFET 71 Query: 183 FNPHDIRLILSDD 195 P D L DD Sbjct: 72 CLPDDEVSSLPDD 84 >gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapiens] Length = 481 Score = 40.0 bits (92), Expect = 0.009 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 126 IGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNP 185 + D + CP+C R P + C H C CL +Y I + + +CP C E F P Sbjct: 10 LADEVNCPIC---QGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRP 66 Query: 186 HDIR 189 R Sbjct: 67 GSFR 70 >gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapiens] Length = 395 Score = 40.0 bits (92), Expect = 0.009 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 126 IGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECTERFNP 185 + D + CP+C R P + C H C CL +Y I + + +CP C E F P Sbjct: 10 LADEVNCPIC---QGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRP 66 Query: 186 HDIR 189 R Sbjct: 67 GSFR 70 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.130 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,410,448 Number of Sequences: 37866 Number of extensions: 1422349 Number of successful extensions: 6404 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 180 Number of HSP's that attempted gapping in prelim test: 5743 Number of HSP's gapped (non-prelim): 534 length of query: 838 length of database: 18,247,518 effective HSP length: 111 effective length of query: 727 effective length of database: 14,044,392 effective search space: 10210272984 effective search space used: 10210272984 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.