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Search of human proteins with 34452707
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
(1235 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens] 2448 0.0
gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens] 1582 0.0
gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens] 1186 0.0
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 70 1e-11
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 67 8e-11
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 67 8e-11
gi|164419758 bromodomain containing 2 [Homo sapiens] 67 8e-11
gi|4826806 bromodomain containing 2 [Homo sapiens] 67 8e-11
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 65 5e-10
gi|50345997 E1A binding protein p300 [Homo sapiens] 64 9e-10
gi|119943102 CREB binding protein isoform b [Homo sapiens] 64 9e-10
gi|119943104 CREB binding protein isoform a [Homo sapiens] 64 9e-10
gi|41350212 bromodomain containing 7 [Homo sapiens] 62 3e-09
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 62 4e-09
gi|38788260 bromodomain PHD finger transcription factor isoform ... 61 6e-09
gi|38788274 bromodomain PHD finger transcription factor isoform ... 61 6e-09
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 59 2e-08
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 59 2e-08
gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens] 59 2e-08
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 59 3e-08
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 59 4e-08
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 59 4e-08
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 58 5e-08
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 58 5e-08
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 57 8e-08
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 57 1e-07
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 54 1e-06
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 53 2e-06
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 53 2e-06
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 53 2e-06
>gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
Length = 1235
Score = 2448 bits (6345), Expect = 0.0
Identities = 1235/1235 (100%), Positives = 1235/1235 (100%)
Query: 1 MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFS 60
MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFS
Sbjct: 1 MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFS 60
Query: 61 QKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYR 120
QKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYR
Sbjct: 61 QKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYR 120
Query: 121 RLKRDAELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRL 180
RLKRDAELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRL
Sbjct: 121 RLKRDAELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRL 180
Query: 181 PTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVNESEMAVASGHLNSTGVLLEVGGVL 240
PTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVNESEMAVASGHLNSTGVLLEVGGVL
Sbjct: 181 PTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVNESEMAVASGHLNSTGVLLEVGGVL 240
Query: 241 PMIHGGEIQQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPP 300
PMIHGGEIQQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPP
Sbjct: 241 PMIHGGEIQQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPP 300
Query: 301 VESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEI 360
VESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEI
Sbjct: 301 VESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEI 360
Query: 361 SMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDFETVGDII 420
SMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDFETVGDII
Sbjct: 361 SMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDFETVGDII 420
Query: 421 AIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTV 480
AIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTV
Sbjct: 421 AIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTV 480
Query: 481 KQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELR 540
KQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELR
Sbjct: 481 KQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELR 540
Query: 541 SQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAE 600
SQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAE
Sbjct: 541 SQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAE 600
Query: 601 TQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDN 660
TQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDN
Sbjct: 601 TQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDN 660
Query: 661 EPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVW 720
EPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVW
Sbjct: 661 EPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVW 720
Query: 721 RAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMF 780
RAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMF
Sbjct: 721 RAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMF 780
Query: 781 QNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQD 840
QNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQD
Sbjct: 781 QNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQD 840
Query: 841 ASEKDSVPMGSPAFLLSLFMGHEWVWLDSEQDHPNDSELSNDCRSLFSSWDSSLDLDVGN 900
ASEKDSVPMGSPAFLLSLFMGHEWVWLDSEQDHPNDSELSNDCRSLFSSWDSSLDLDVGN
Sbjct: 841 ASEKDSVPMGSPAFLLSLFMGHEWVWLDSEQDHPNDSELSNDCRSLFSSWDSSLDLDVGN 900
Query: 901 WRETEDPEAEELEESSPEREPSELLVGDGGSEESQEAARKASHQNLLHFLSEVAYLMEPL 960
WRETEDPEAEELEESSPEREPSELLVGDGGSEESQEAARKASHQNLLHFLSEVAYLMEPL
Sbjct: 901 WRETEDPEAEELEESSPEREPSELLVGDGGSEESQEAARKASHQNLLHFLSEVAYLMEPL 960
Query: 961 CISSNESSEGCCPPSGTRQEGREIKASEGERELCRETEELSAKGDPLVAEKPLGENGKPE 1020
CISSNESSEGCCPPSGTRQEGREIKASEGERELCRETEELSAKGDPLVAEKPLGENGKPE
Sbjct: 961 CISSNESSEGCCPPSGTRQEGREIKASEGERELCRETEELSAKGDPLVAEKPLGENGKPE 1020
Query: 1021 VASAPSVICTVQGLLTESEEGEAQQESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPL 1080
VASAPSVICTVQGLLTESEEGEAQQESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPL
Sbjct: 1021 VASAPSVICTVQGLLTESEEGEAQQESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPL 1080
Query: 1081 VDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQAPGY 1140
VDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQAPGY
Sbjct: 1081 VDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQAPGY 1140
Query: 1141 KDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREV 1200
KDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREV
Sbjct: 1141 KDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREV 1200
Query: 1201 LEQIQVLNIWLDKRKGSSSLEGEPANPVDDGKPVF 1235
LEQIQVLNIWLDKRKGSSSLEGEPANPVDDGKPVF
Sbjct: 1201 LEQIQVLNIWLDKRKGSSSLEGEPANPVDDGKPVF 1235
>gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]
Length = 951
Score = 1582 bits (4096), Expect = 0.0
Identities = 833/934 (89%), Positives = 838/934 (89%), Gaps = 73/934 (7%)
Query: 1 MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFS 60
MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFS
Sbjct: 1 MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFS 60
Query: 61 QKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYR 120
QKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYR
Sbjct: 61 QKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYR 120
Query: 121 RLKRDAELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQA-------- 172
RLKRDAELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQA
Sbjct: 121 RLKRDAELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRL 180
Query: 173 ----VKTP----------------------------PRRLPTVMVRS--PIDSASPGGDY 198
V++P P LP+ V S I P G
Sbjct: 181 PTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSA 240
Query: 199 PL-GDLTPTTMEEATSG------------------------------VNESEMAVASGHL 227
PL +TP T + VNESEMAVASGHL
Sbjct: 241 PLEAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHL 300
Query: 228 NSTGVLLEVGGVLPMIHGGEIQQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPLASFTT 287
NSTGVLLEVGGVLPMIHGGEIQQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPLASFTT
Sbjct: 301 NSTGVLLEVGGVLPMIHGGEIQQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPLASFTT 360
Query: 288 VASEPPVKLVPPPVESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGD 347
VASEPPVKLVPPPVESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGD
Sbjct: 361 VASEPPVKLVPPPVESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGD 420
Query: 348 PHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYT 407
PHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYT
Sbjct: 421 PHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYT 480
Query: 408 GEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQER 467
GEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQER
Sbjct: 481 GEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQER 540
Query: 468 DKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAG 527
DKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAG
Sbjct: 541 DKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAG 600
Query: 528 VVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPS 587
VVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPS
Sbjct: 601 VVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPS 660
Query: 588 HGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKE 647
HGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKE
Sbjct: 661 HGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKE 720
Query: 648 EDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQ 707
EDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQ
Sbjct: 721 EDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQ 780
Query: 708 AQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIR 767
AQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIR
Sbjct: 781 AQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIR 840
Query: 768 STAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISA 827
STAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISA
Sbjct: 841 STAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISA 900
Query: 828 KSLRGRDSTRKQDASEKDSVPMGSPAFLLSLFMG 861
KSLRGRDSTRKQDASEKDSVPMGSPAFLLSLF G
Sbjct: 901 KSLRGRDSTRKQDASEKDSVPMGSPAFLLSLFDG 934
Score = 174 bits (441), Expect = 5e-43
Identities = 88/179 (49%), Positives = 128/179 (71%), Gaps = 10/179 (5%)
Query: 1037 ESEEGEAQ----QESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPL-----VDTLFSH 1087
E E+G ++ +E K EDQGE Y+SEM+++PP E DD F+I L D++ S
Sbjct: 704 EEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSS 763
Query: 1088 ATSSKLTDLSQD-DPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQAPGYKDVVKR 1146
SS+ + S+D + +Q ++KK ++ VW+ A+HR+++ FL+PV++ APGY +V+R
Sbjct: 764 PASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQR 823
Query: 1147 PMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQIQ 1205
PMDL+++K+N+ G IR+ A+F RD+MLMFQNAVMYN SDH VYHMAVEM+R+VLEQIQ
Sbjct: 824 PMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQ 882
>gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]
Length = 757
Score = 1186 bits (3069), Expect = 0.0
Identities = 640/748 (85%), Positives = 646/748 (86%), Gaps = 56/748 (7%)
Query: 148 KKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTT 207
KKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTT
Sbjct: 8 KKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTT 67
Query: 208 MEEATSGVNESEMAVASGHLNSTGVLLEVG-------GVLPMIHGGEIQQTPNT------ 254
MEEATSG V G L ST V G G P+ E TP T
Sbjct: 68 MEEATSG-------VTPGTLPSTPVTSFPGIPDTLPPGSAPL----EAPMTPVTDDSPQK 116
Query: 255 --VAASPAASGAPTLSRLLEAGPTQFTTPL---ASFTTVAS------------------- 290
+ +P LS LL+ G T+P S VAS
Sbjct: 117 KMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMI 176
Query: 291 ------EPP--VKLVPPPVESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPM 342
+ P V P ESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPM
Sbjct: 177 HGGEIQQTPNTVAASPAASESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPM 236
Query: 343 EAVGDPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDI 402
EAVGDPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDI
Sbjct: 237 EAVGDPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDI 296
Query: 403 AVSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHP 462
AVSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHP
Sbjct: 297 AVSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHP 356
Query: 463 IQQERDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGA 522
IQQERDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGA
Sbjct: 357 IQQERDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGA 416
Query: 523 EIVAGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPES 582
EIVAGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPES
Sbjct: 417 EIVAGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPES 476
Query: 583 MLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASL 642
MLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASL
Sbjct: 477 MLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASL 536
Query: 643 EEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSED 702
EEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSED
Sbjct: 537 EEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSED 596
Query: 703 QEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIE 762
QEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIE
Sbjct: 597 QEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIE 656
Query: 763 NGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSE 822
NGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSE
Sbjct: 657 NGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSE 716
Query: 823 SGISAKSLRGRDSTRKQDASEKDSVPMG 850
SGISAKSLRGRDSTRKQDASEKD G
Sbjct: 717 SGISAKSLRGRDSTRKQDASEKDGGTRG 744
Score = 174 bits (441), Expect = 5e-43
Identities = 88/179 (49%), Positives = 128/179 (71%), Gaps = 10/179 (5%)
Query: 1037 ESEEGEAQ----QESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPL-----VDTLFSH 1087
E E+G ++ +E K EDQGE Y+SEM+++PP E DD F+I L D++ S
Sbjct: 525 EEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSS 584
Query: 1088 ATSSKLTDLSQD-DPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQAPGYKDVVKR 1146
SS+ + S+D + +Q ++KK ++ VW+ A+HR+++ FL+PV++ APGY +V+R
Sbjct: 585 PASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQR 644
Query: 1147 PMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQIQ 1205
PMDL+++K+N+ G IR+ A+F RD+MLMFQNAVMYN SDH VYHMAVEM+R+VLEQIQ
Sbjct: 645 PMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQ 703
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 70.5 bits (171), Expect = 1e-11
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 9/150 (6%)
Query: 707 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 763
Q Q + + +W+ H++A F QPV D I P YH I++ PMD+ TIKK +EN
Sbjct: 38 QLQYMQNVVVKTLWK----HQFAWPFYQPV-DAIKLNLPDYHKIIKNPMDMGTIKKRLEN 92
Query: 764 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQL-IMQTSE 822
S +E +D MF N +YN D+ MA +++ L+++ Q ++ ++ +
Sbjct: 93 NYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAP 152
Query: 823 SGISAKSLRGRDSTRKQDASEKDSVPMGSP 852
G K G S Q + SV +P
Sbjct: 153 KGKGRKPAAGAQSAGTQQVAAVSSVSPATP 182
Score = 60.1 bits (144), Expect = 1e-08
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 728 YANVFLQPVTDDIAP--GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVM 785
YA F +PV + YH I++ PMDLST+K+ ++ F D+ LMF N
Sbjct: 330 YAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYK 389
Query: 786 YNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSL-RGRDSTRKQDASEK 844
YN DH+V MA ++Q DV E + + + + +A + +G +S+R + S
Sbjct: 390 YNPPDHEVVAMARKLQ-DVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSS 448
Query: 845 DS 846
DS
Sbjct: 449 DS 450
Score = 54.3 bits (129), Expect = 7e-07
Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 1102 VQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSER--QAPGYKDVVKRPMDLTSLKRNLSK 1159
+ +HL + ++L ++ PF KPV + Y D++K PMDL+++KR +
Sbjct: 308 LSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDG 367
Query: 1160 GRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMR 1197
F D+ LMF N YN DH V MA +++
Sbjct: 368 REYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQ 405
Score = 50.8 bits (120), Expect = 8e-06
Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 1115 VWKMIASHRFSSPFLKPVS--ERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDL 1172
V K + H+F+ PF +PV + P Y ++K PMD+ ++K+ L + ++ ++D
Sbjct: 46 VVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDF 105
Query: 1173 MLMFQNAVMYNDSDHHVYHMAVEMRREVLEQI 1204
MF N +YN + MA + + L+++
Sbjct: 106 NTMFTNCYIYNKPTDDIVLMAQALEKIFLQKV 137
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 67.4 bits (163), Expect = 8e-11
Identities = 68/233 (29%), Positives = 96/233 (41%), Gaps = 42/233 (18%)
Query: 580 PESMLSPSHGSNPIED--PLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVS 637
P+ P+ P++ P+ A T + +K ++ T + I D +
Sbjct: 255 PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI----------DPIH 304
Query: 638 EAASLE-EPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQF 696
E SL EPK G+ S +PP + D Q H + SS S Q
Sbjct: 305 EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEK--SSKVSEQL 354
Query: 697 SVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHS---IVQRPMD 753
CS + + A+K + YA F +PV D A G H I++ PMD
Sbjct: 355 KCCSGILKEMFAKK--------------HAAYAWPFYKPV-DVEALGLHDYCDIIKHPMD 399
Query: 754 LSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLE 806
+STIK +E R EF D+ LMF N YN DH+V MA ++Q DV E
Sbjct: 400 MSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ-DVFE 451
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 17/172 (9%)
Query: 679 QSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTD 738
Q A + P P +S + ++ Q Q + + + +W+ H++A F QPV D
Sbjct: 36 QPANAASTNPPPPETSNPN--KPKRQTNQLQYLLRVVLKTLWK----HQFAWPFQQPV-D 88
Query: 739 DIA---PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYH 795
+ P Y+ I++ PMD+ TIKK +EN + E +D MF N +YN D+
Sbjct: 89 AVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVL 148
Query: 796 MAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSV 847
MA +++ L++I + + T E+ I +GR RK+ + K V
Sbjct: 149 MAEALEKLFLQKINE-------LPTEETEIMIVQAKGRGRGRKETGTAKPGV 193
Score = 53.1 bits (126), Expect = 2e-06
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 1124 FSSPFLKPVSERQAPG---YKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAV 1180
++ PF KPV + +A G Y D++K PMD++++K L R +F D+ LMF N
Sbjct: 372 YAWPFYKPV-DVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCY 430
Query: 1181 MYNDSDHHVYHMAVEMR 1197
YN DH V MA +++
Sbjct: 431 KYNPPDHEVVAMARKLQ 447
Score = 50.8 bits (120), Expect = 8e-06
Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Query: 1107 LFKKTLLPVWKMIASHRFSSPFLKPVS--ERQAPGYKDVVKRPMDLTSLKRNLSKGRIRT 1164
L + L +WK H+F+ PF +PV + P Y ++K PMD+ ++K+ L
Sbjct: 66 LLRVVLKTLWK----HQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN 121
Query: 1165 MAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQIQVL 1207
+ ++D MF N +YN + MA + + L++I L
Sbjct: 122 AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL 164
Score = 33.5 bits (75), Expect = 1.3
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 9/83 (10%)
Query: 254 TVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPPVESVSQATIVMMP 313
T A P S P TQ +TP + T + PPV+ P P +V+ IV P
Sbjct: 186 TGTAKPGVSTVPNT--------TQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTP 237
Query: 314 ALPAPSSAPAVSTTESVAPVSQP 336
+ P + T V P QP
Sbjct: 238 VMTVVPPQP-LQTPPPVPPQPQP 259
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 67.4 bits (163), Expect = 8e-11
Identities = 68/233 (29%), Positives = 96/233 (41%), Gaps = 42/233 (18%)
Query: 580 PESMLSPSHGSNPIED--PLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVS 637
P+ P+ P++ P+ A T + +K ++ T + I D +
Sbjct: 255 PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI----------DPIH 304
Query: 638 EAASLE-EPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQF 696
E SL EPK G+ S +PP + D Q H + SS S Q
Sbjct: 305 EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEK--SSKVSEQL 354
Query: 697 SVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHS---IVQRPMD 753
CS + + A+K + YA F +PV D A G H I++ PMD
Sbjct: 355 KCCSGILKEMFAKK--------------HAAYAWPFYKPV-DVEALGLHDYCDIIKHPMD 399
Query: 754 LSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLE 806
+STIK +E R EF D+ LMF N YN DH+V MA ++Q DV E
Sbjct: 400 MSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ-DVFE 451
Score = 66.2 bits (160), Expect = 2e-10
Identities = 48/172 (27%), Positives = 81/172 (47%), Gaps = 17/172 (9%)
Query: 679 QSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTD 738
Q A + P P +S + ++ Q Q + + + +W+ H++A F QPV D
Sbjct: 36 QPANAASTNPPPPETSNPN--KPKRQTNQLQYLLRVVLKTLWK----HQFAWPFQQPV-D 88
Query: 739 DIA---PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYH 795
+ P Y+ I++ PMD+ TIKK +EN + E +D MF N +YN D+
Sbjct: 89 AVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVL 148
Query: 796 MAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSV 847
MA +++ L++I + + T E+ I +GR RK+ + K V
Sbjct: 149 MAEALEKLFLQKINE-------LPTEETEIMIVQAKGRGRGRKETGTAKPGV 193
Score = 53.1 bits (126), Expect = 2e-06
Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 1124 FSSPFLKPVSERQAPG---YKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAV 1180
++ PF KPV + +A G Y D++K PMD++++K L R +F D+ LMF N
Sbjct: 372 YAWPFYKPV-DVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCY 430
Query: 1181 MYNDSDHHVYHMAVEMR 1197
YN DH V MA +++
Sbjct: 431 KYNPPDHEVVAMARKLQ 447
Score = 50.8 bits (120), Expect = 8e-06
Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Query: 1107 LFKKTLLPVWKMIASHRFSSPFLKPVS--ERQAPGYKDVVKRPMDLTSLKRNLSKGRIRT 1164
L + L +WK H+F+ PF +PV + P Y ++K PMD+ ++K+ L
Sbjct: 66 LLRVVLKTLWK----HQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN 121
Query: 1165 MAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQIQVL 1207
+ ++D MF N +YN + MA + + L++I L
Sbjct: 122 AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINEL 164
Score = 35.0 bits (79), Expect = 0.44
Identities = 29/108 (26%), Positives = 39/108 (36%), Gaps = 7/108 (6%)
Query: 241 PMIHGGEIQQTPNTVAASPAASGAPTLSR-----LLEAGPTQFTTPLASFTTVASEPPVK 295
P++ + Q P + P S L + Q TPL V S+PP
Sbjct: 898 PLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP 957
Query: 296 LVPPPVESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPME 343
L PPP SV Q P P P P + P +P + PM+
Sbjct: 958 LPPPPHPSVQQQLQQQPP--PPPPPQPQPPPQQQHQPPPRPVHLQPMQ 1003
Score = 33.5 bits (75), Expect = 1.3
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 9/83 (10%)
Query: 254 TVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPPVESVSQATIVMMP 313
T A P S P TQ +TP + T + PPV+ P P +V+ IV P
Sbjct: 186 TGTAKPGVSTVPNT--------TQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTP 237
Query: 314 ALPAPSSAPAVSTTESVAPVSQP 336
+ P + T V P QP
Sbjct: 238 VMTVVPPQP-LQTPPPVPPQPQP 259
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 67.4 bits (163), Expect = 8e-11
Identities = 40/82 (48%), Positives = 49/82 (59%), Gaps = 5/82 (6%)
Query: 728 YANVFLQPVTDDIAPG---YHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAV 784
YA F +PV D A G YH I++ PMDLST+K+ +EN R EF D+ LMF N
Sbjct: 368 YAWPFYKPV-DASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCY 426
Query: 785 MYNSSDHDVYHMAVEMQRDVLE 806
YN DHDV MA ++Q DV E
Sbjct: 427 KYNPPDHDVVAMARKLQ-DVFE 447
Score = 64.3 bits (155), Expect = 7e-10
Identities = 40/142 (28%), Positives = 72/142 (50%), Gaps = 14/142 (9%)
Query: 707 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 763
Q Q + K + +W+ H++A F QPV D + P YH I+++PMD+ TIK+ +EN
Sbjct: 78 QLQYLHKVVMKALWK----HQFAWPFRQPV-DAVKLGLPDYHKIIKQPMDMGTIKRRLEN 132
Query: 764 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQI------QQFLATQLI 817
+ +E +D MF N +YN D+ MA +++ L+++ +Q L +
Sbjct: 133 NYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIP 192
Query: 818 MQTSESGISAKSLRGRDSTRKQ 839
+ + G +L+G ++ Q
Sbjct: 193 KNSHKKGAKLAALQGSVTSAHQ 214
Score = 57.0 bits (136), Expect = 1e-07
Identities = 41/124 (33%), Positives = 57/124 (45%), Gaps = 17/124 (13%)
Query: 1080 LVDTLFSHATSSK---LTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQ 1136
L D+ H +S K L + + LL KK W PF KPV +
Sbjct: 331 LPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAW----------PFYKPV-DAS 379
Query: 1137 APG---YKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMA 1193
A G Y D++K PMDL+++KR + R +F D+ LMF N YN DH V MA
Sbjct: 380 ALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMA 439
Query: 1194 VEMR 1197
+++
Sbjct: 440 RKLQ 443
Score = 52.0 bits (123), Expect = 3e-06
Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Query: 1107 LFKKTLLPVWKMIASHRFSSPFLKPVSERQA--PGYKDVVKRPMDLTSLKRNLSKGRIRT 1164
L K + +WK H+F+ PF +PV + P Y ++K+PMD+ ++KR L
Sbjct: 82 LHKVVMKALWK----HQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWA 137
Query: 1165 MAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQI 1204
++ ++D MF N +YN + MA + + L+++
Sbjct: 138 ASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKV 177
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 67.4 bits (163), Expect = 8e-11
Identities = 40/82 (48%), Positives = 49/82 (59%), Gaps = 5/82 (6%)
Query: 728 YANVFLQPVTDDIAPG---YHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAV 784
YA F +PV D A G YH I++ PMDLST+K+ +EN R EF D+ LMF N
Sbjct: 368 YAWPFYKPV-DASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCY 426
Query: 785 MYNSSDHDVYHMAVEMQRDVLE 806
YN DHDV MA ++Q DV E
Sbjct: 427 KYNPPDHDVVAMARKLQ-DVFE 447
Score = 64.3 bits (155), Expect = 7e-10
Identities = 40/142 (28%), Positives = 72/142 (50%), Gaps = 14/142 (9%)
Query: 707 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 763
Q Q + K + +W+ H++A F QPV D + P YH I+++PMD+ TIK+ +EN
Sbjct: 78 QLQYLHKVVMKALWK----HQFAWPFRQPV-DAVKLGLPDYHKIIKQPMDMGTIKRRLEN 132
Query: 764 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQI------QQFLATQLI 817
+ +E +D MF N +YN D+ MA +++ L+++ +Q L +
Sbjct: 133 NYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIP 192
Query: 818 MQTSESGISAKSLRGRDSTRKQ 839
+ + G +L+G ++ Q
Sbjct: 193 KNSHKKGAKLAALQGSVTSAHQ 214
Score = 57.0 bits (136), Expect = 1e-07
Identities = 41/124 (33%), Positives = 57/124 (45%), Gaps = 17/124 (13%)
Query: 1080 LVDTLFSHATSSK---LTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQ 1136
L D+ H +S K L + + LL KK W PF KPV +
Sbjct: 331 LPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAW----------PFYKPV-DAS 379
Query: 1137 APG---YKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMA 1193
A G Y D++K PMDL+++KR + R +F D+ LMF N YN DH V MA
Sbjct: 380 ALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMA 439
Query: 1194 VEMR 1197
+++
Sbjct: 440 RKLQ 443
Score = 52.0 bits (123), Expect = 3e-06
Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Query: 1107 LFKKTLLPVWKMIASHRFSSPFLKPVSERQA--PGYKDVVKRPMDLTSLKRNLSKGRIRT 1164
L K + +WK H+F+ PF +PV + P Y ++K+PMD+ ++KR L
Sbjct: 82 LHKVVMKALWK----HQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWA 137
Query: 1165 MAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQI 1204
++ ++D MF N +YN + MA + + L+++
Sbjct: 138 ASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKV 177
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 64.7 bits (156), Expect = 5e-10
Identities = 73/306 (23%), Positives = 124/306 (40%), Gaps = 37/306 (12%)
Query: 901 WRETEDPEAEELEESSPEREPSELLVGDGGSEESQEAARKASHQNLLHFLSEVAYLMEPL 960
WR+ + E S ER+ +LL D E A+K ++ + L
Sbjct: 253 WRQVTESFRERT--SLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHL 310
Query: 961 CISSNESSEGCCPPSGTRQEGREIKASEGERELCRETEELSAKGDPLVAEKPLGENGKPE 1020
I + E P TR E ++ K E ER++ ++ E+ L E K E
Sbjct: 311 SIKPVKQEE---TPVLTRIEKQKRKEEEEERQILLAVQKKEQ-------EQMLKEERKRE 360
Query: 1021 V---ASAPSVICTVQ-----GLLTESEEGEAQQESKGEDQGEVYVSEMEDQPPSGECDDA 1072
+ A +C+V+ L+ S + + K ++ +++ ++ PP
Sbjct: 361 LEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPP------- 413
Query: 1073 FNIKETPLVDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPV 1132
E +D K DL + D D K L ++ +H+ S PFL+PV
Sbjct: 414 ----ELSHLDPNSPMREEKKTKDLFELD--DDFTAMYKVL----DVVKAHKDSWPFLEPV 463
Query: 1133 SERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHM 1192
E AP Y ++K PMD++S+++ L+ G T +F+ D+ MF+N YN M
Sbjct: 464 DESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKM 523
Query: 1193 AVEMRR 1198
+ + R
Sbjct: 524 SDNLER 529
Score = 58.9 bits (141), Expect = 3e-08
Identities = 26/77 (33%), Positives = 45/77 (58%)
Query: 726 HRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVM 785
H+ + FL+PV + AP Y+ I++ PMD+S+++K + GL + EF D+ MF+N
Sbjct: 453 HKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRK 512
Query: 786 YNSSDHDVYHMAVEMQR 802
YN + M+ ++R
Sbjct: 513 YNGESSEYTKMSDNLER 529
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 63.9 bits (154), Expect = 9e-10
Identities = 72/307 (23%), Positives = 117/307 (38%), Gaps = 31/307 (10%)
Query: 504 PSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAI 563
P ++ P P ++ V P+ P + Q STAA +
Sbjct: 873 PQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLL 932
Query: 564 GKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQI 623
TPL+ + PS S + AE Q E+ K E
Sbjct: 933 PPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVD------- 985
Query: 624 KDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTL 683
+ P + + ED +SE+ + E + E +E+ E + E +D
Sbjct: 986 QPEPADTQPED-ISESKVEDCKMESTETEERSTELKTE--IKEEEDQ------------- 1029
Query: 684 ADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANV-FLQPVTDDIA- 741
PS+ A+ + ++ I + ++A+M A ++ F QPV +
Sbjct: 1030 ----PSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLG 1085
Query: 742 -PGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEM 800
P Y IV+ PMDLSTIK+ ++ G + ++ DI LMF NA +YN VY ++
Sbjct: 1086 IPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKL 1145
Query: 801 QRDVLEQ 807
+V EQ
Sbjct: 1146 S-EVFEQ 1151
Score = 59.7 bits (143), Expect = 2e-08
Identities = 63/223 (28%), Positives = 96/223 (43%), Gaps = 26/223 (11%)
Query: 1006 PLVAEKPLGENGKP------EVASAPSVICTV---QGLLTESEEGEAQQESKGE-DQGEV 1055
PL+ +P +P +V++ PS T Q + + E + E+K E DQ E
Sbjct: 930 PLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEP 989
Query: 1056 YVSEMEDQPPSGECDDAFNIKETPL----VDTLFSHATSSKLTDLSQDDPVQDHL---LF 1108
++ ED S D ET + T T +Q P +F
Sbjct: 990 ADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIF 1049
Query: 1109 K-----KTLLPVWKMIASHRFSS-PFLKPVSERQA--PGYKDVVKRPMDLTSLKRNLSKG 1160
K + L+P + + S PF +PV + P Y D+VK PMDL+++KR L G
Sbjct: 1050 KPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTG 1109
Query: 1161 RIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQ 1203
+ + Q++ D+ LMF NA +YN VY ++ EV EQ
Sbjct: 1110 QYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKL-SEVFEQ 1151
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 63.9 bits (154), Expect = 9e-10
Identities = 56/188 (29%), Positives = 86/188 (45%), Gaps = 21/188 (11%)
Query: 1036 TESEEGEAQQ-ESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPL----------VDTL 1084
T++E+ E ESKGE + E+ +++ E D K P+ V+
Sbjct: 963 TQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVK 1022
Query: 1085 FSHATSSKLTDLSQDDPVQDHL-LFK-----KTLLPVWKMIASHRFSS-PFLKPVSERQA 1137
+SS T P Q +FK + L+P + + S PF +PV +
Sbjct: 1023 EEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLL 1082
Query: 1138 --PGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVE 1195
P Y D+VK PMDL+++KR L G+ + Q++ D+ LMF NA +YN VY +
Sbjct: 1083 GIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSK 1142
Query: 1196 MRREVLEQ 1203
+ EV EQ
Sbjct: 1143 L-AEVFEQ 1149
Score = 59.3 bits (142), Expect = 2e-08
Identities = 66/284 (23%), Positives = 116/284 (40%), Gaps = 32/284 (11%)
Query: 530 PATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHG 589
P T ++PP + + ++ + + + + + V T +S S + S
Sbjct: 892 PQTPVQPPSVATPQSSQQQPTPVHAQ--PPGTPLSQAAASIDNRVPTPSSVASAETNSQQ 949
Query: 590 SNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEED 649
P LE +T+ + E ++ ES K P + E+ + A+ ++E +
Sbjct: 950 PGPDVPVLEMKTETQAEDTEPDPGES--------KGEPRSEMMEEDLQGASQVKEETDIA 1001
Query: 650 QGEGYLSEMDNEPP---VSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAI 706
+ + E+D + P V ++ S N T T PS P F
Sbjct: 1002 EQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTS----PSQPRKKIFK--------- 1048
Query: 707 QAQKIWKKAIMLVWRAAANHRYANV-FLQPVTDDIA--PGYHSIVQRPMDLSTIKKNIEN 763
+ ++A+M A ++ F QPV + P Y IV+ PMDLSTIK+ ++
Sbjct: 1049 --PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDT 1106
Query: 764 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQ 807
G + ++ D+ LMF NA +YN VY ++ +V EQ
Sbjct: 1107 GQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL-AEVFEQ 1149
Score = 31.2 bits (69), Expect = 6.4
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 26/135 (19%)
Query: 251 TPNTVAASPAASGAPTLSRLLEAGPT-QFTTPLASFTTVASEPPVKLVPPPVES------ 303
TP +V ++ PT+ +A T Q TP+ +VA+ + P PV +
Sbjct: 864 TPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQP-PSVATPQSSQQQPTPVHAQPPGTP 922
Query: 304 VSQATIVMMPALPAPSSAPAVST---------------TESVAPVSQPDNCVPMEAVGDP 348
+SQA + +P PSS + T TE+ A ++PD P E+ G+P
Sbjct: 923 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPD---PGESKGEP 979
Query: 349 HTVTVSMDSSEISMI 363
+ + D S +
Sbjct: 980 RSEMMEEDLQGASQV 994
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 63.9 bits (154), Expect = 9e-10
Identities = 56/188 (29%), Positives = 86/188 (45%), Gaps = 21/188 (11%)
Query: 1036 TESEEGEAQQ-ESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPL----------VDTL 1084
T++E+ E ESKGE + E+ +++ E D K P+ V+
Sbjct: 1001 TQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVK 1060
Query: 1085 FSHATSSKLTDLSQDDPVQDHL-LFK-----KTLLPVWKMIASHRFSS-PFLKPVSERQA 1137
+SS T P Q +FK + L+P + + S PF +PV +
Sbjct: 1061 EEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLL 1120
Query: 1138 --PGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVE 1195
P Y D+VK PMDL+++KR L G+ + Q++ D+ LMF NA +YN VY +
Sbjct: 1121 GIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSK 1180
Query: 1196 MRREVLEQ 1203
+ EV EQ
Sbjct: 1181 L-AEVFEQ 1187
Score = 59.3 bits (142), Expect = 2e-08
Identities = 66/284 (23%), Positives = 116/284 (40%), Gaps = 32/284 (11%)
Query: 530 PATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHG 589
P T ++PP + + ++ + + + + + V T +S S + S
Sbjct: 930 PQTPVQPPSVATPQSSQQQPTPVHAQ--PPGTPLSQAAASIDNRVPTPSSVASAETNSQQ 987
Query: 590 SNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEED 649
P LE +T+ + E ++ ES K P + E+ + A+ ++E +
Sbjct: 988 PGPDVPVLEMKTETQAEDTEPDPGES--------KGEPRSEMMEEDLQGASQVKEETDIA 1039
Query: 650 QGEGYLSEMDNEPP---VSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAI 706
+ + E+D + P V ++ S N T T PS P F
Sbjct: 1040 EQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTS----PSQPRKKIFK--------- 1086
Query: 707 QAQKIWKKAIMLVWRAAANHRYANV-FLQPVTDDIA--PGYHSIVQRPMDLSTIKKNIEN 763
+ ++A+M A ++ F QPV + P Y IV+ PMDLSTIK+ ++
Sbjct: 1087 --PEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDT 1144
Query: 764 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQ 807
G + ++ D+ LMF NA +YN VY ++ +V EQ
Sbjct: 1145 GQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKL-AEVFEQ 1187
Score = 31.2 bits (69), Expect = 6.4
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 26/135 (19%)
Query: 251 TPNTVAASPAASGAPTLSRLLEAGPT-QFTTPLASFTTVASEPPVKLVPPPVES------ 303
TP +V ++ PT+ +A T Q TP+ +VA+ + P PV +
Sbjct: 902 TPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQP-PSVATPQSSQQQPTPVHAQPPGTP 960
Query: 304 VSQATIVMMPALPAPSSAPAVST---------------TESVAPVSQPDNCVPMEAVGDP 348
+SQA + +P PSS + T TE+ A ++PD P E+ G+P
Sbjct: 961 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPD---PGESKGEP 1017
Query: 349 HTVTVSMDSSEISMI 363
+ + D S +
Sbjct: 1018 RSEMMEEDLQGASQV 1032
>gi|41350212 bromodomain containing 7 [Homo sapiens]
Length = 651
Score = 62.4 bits (150), Expect = 3e-09
Identities = 69/269 (25%), Positives = 111/269 (41%), Gaps = 36/269 (13%)
Query: 577 EASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGV 636
E + S S H S+ ED + + +HK K+ K PGE E G
Sbjct: 33 EVTELSTGSSGHDSSLFEDKNDHD-KHKDRKRKKRKKGE--------KQIPGE---EKGR 80
Query: 637 SEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLA--DSIPSSPASS 694
E+ K+ D+ ++NE +E D LQ H D P P +S
Sbjct: 81 KRRRVKEDKKKRDR-----DRVENE---AEKD---------LQCHAPVRLDLPPEKPLTS 123
Query: 695 QFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDL 754
+ QE ++ + ++A+ + R + F PVTD IAPGY I++ PMD
Sbjct: 124 SLA----KQEEVEQTPL-QEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDF 178
Query: 755 STIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLAT 814
ST+K+ I+N +S E + + LM NA++YN + Y A ++ ++ + Q
Sbjct: 179 STMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQ 238
Query: 815 QLIMQTSESGISAKSLRGRDSTRKQDASE 843
L K+ + +D T + E
Sbjct: 239 SLKQSIDFMADLQKTRKQKDGTDTSQSGE 267
Score = 44.3 bits (103), Expect = 7e-04
Identities = 21/72 (29%), Positives = 40/72 (55%)
Query: 1125 SSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYND 1184
S+ F PV++ APGY ++K PMD +++K + +++ + + LM NA++YN
Sbjct: 153 SAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNK 212
Query: 1185 SDHHVYHMAVEM 1196
+ Y A ++
Sbjct: 213 PETIYYKAAKKL 224
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 61.6 bits (148), Expect = 4e-09
Identities = 27/78 (34%), Positives = 45/78 (57%)
Query: 1121 SHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAV 1180
+H + PFL PV+ + PGYK V+K+PMD ++++ LS G+ + F D+ L+F N
Sbjct: 2078 THEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCE 2137
Query: 1181 MYNDSDHHVYHMAVEMRR 1198
+N+ D + MR+
Sbjct: 2138 TFNEDDSDIGRAGHNMRK 2155
Score = 57.4 bits (137), Expect = 8e-08
Identities = 40/175 (22%), Positives = 74/175 (42%), Gaps = 31/175 (17%)
Query: 628 GEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSI 687
G+ E+ED S ++SL+ ++ + + ++ SI+ + +S T
Sbjct: 2012 GDTEDEDSASTSSSLKRGNKDLKKR-------------KMEENTSINLSKQESFTSVKK- 2057
Query: 688 PSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSI 747
P S ++CS ++ H A FL PV + PGY +
Sbjct: 2058 PKRDDSKDLALCS-----------------MILTEMETHEDAWPFLLPVNLKLVPGYKKV 2100
Query: 748 VQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 802
+++PMD STI++ + +G + F D+ L+F N +N D D+ M++
Sbjct: 2101 IKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRK 2155
Score = 33.5 bits (75), Expect = 1.3
Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 16/86 (18%)
Query: 867 LDSEQDHPNDSELSNDCRSLFSSWDSSLDLDVGNWRETEDPEAEELEESSPEREPSELLV 926
++S + +DS S+D S S S DL+ E E+ E + +EES
Sbjct: 239 MESSSNSDSDSGTSSDTSSEGISSSDSDDLE-----EDEEEEDQSIEESE---------- 283
Query: 927 GDGGSEESQEAARKASHQNLLHFLSE 952
D S+ EA K+++Q LLH +S+
Sbjct: 284 -DDDSDSESEAQHKSNNQVLLHGISD 308
Score = 32.7 bits (73), Expect = 2.2
Identities = 36/112 (32%), Positives = 50/112 (44%), Gaps = 24/112 (21%)
Query: 566 GDETPLTNVKTEASP-----ESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEE----SG 616
G++TP V ASP + S+ NP++ TQH + SL E+
Sbjct: 546 GNQTP---VMPSASPILHSQGKEKAVSNNVNPVK------TQHHSHPAKSLVEQFRGTDS 596
Query: 617 TIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESD 668
I S+ + EDEEED E EE E+D+ + SE D+ SESD
Sbjct: 597 DIPSSKDSEDSNEDEEEDDEEED---EEDDEDDESDDSQSESDSN---SESD 642
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 61.2 bits (147), Expect = 6e-09
Identities = 29/97 (29%), Positives = 54/97 (55%)
Query: 719 VWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIML 778
V R+ H+ A FL+PV + AP Y+ +++ PMDL+T+++ ++ EF D+
Sbjct: 2796 VLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2855
Query: 779 MFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQ 815
+F N YN SD Y A ++ +++++ F A++
Sbjct: 2856 IFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASR 2892
Score = 60.5 bits (145), Expect = 1e-08
Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 1115 VWKMIASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLML 1174
V + + +H+ + PFL+PV AP Y V+K PMDL +++ + + + +F+ D+
Sbjct: 2796 VLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2855
Query: 1175 MFQNAVMYNDSDHHVYHMAVEMRREVLEQIQV 1206
+F N YN SD Y A EVLE V
Sbjct: 2856 IFDNCRYYNPSDSPFYQCA-----EVLESFFV 2882
Score = 32.3 bits (72), Expect = 2.9
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 629 EDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFS-IHNATLQSHTLADSI 687
E+EEEDG +E E EED+ E + D + + DD S ++ +SH+ S
Sbjct: 144 EEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSST 203
Query: 688 P 688
P
Sbjct: 204 P 204
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 61.2 bits (147), Expect = 6e-09
Identities = 29/97 (29%), Positives = 54/97 (55%)
Query: 719 VWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIML 778
V R+ H+ A FL+PV + AP Y+ +++ PMDL+T+++ ++ EF D+
Sbjct: 2813 VLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2872
Query: 779 MFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQ 815
+F N YN SD Y A ++ +++++ F A++
Sbjct: 2873 IFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASR 2909
Score = 60.5 bits (145), Expect = 1e-08
Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 1115 VWKMIASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLML 1174
V + + +H+ + PFL+PV AP Y V+K PMDL +++ + + + +F+ D+
Sbjct: 2813 VLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2872
Query: 1175 MFQNAVMYNDSDHHVYHMAVEMRREVLEQIQV 1206
+F N YN SD Y A EVLE V
Sbjct: 2873 IFDNCRYYNPSDSPFYQCA-----EVLESFFV 2899
Score = 32.3 bits (72), Expect = 2.9
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 629 EDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFS-IHNATLQSHTLADSI 687
E+EEEDG +E E EED+ E + D + + DD S ++ +SH+ S
Sbjct: 144 EEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSST 203
Query: 688 P 688
P
Sbjct: 204 P 204
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 59.3 bits (142), Expect = 2e-08
Identities = 29/77 (37%), Positives = 44/77 (57%)
Query: 1119 IASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQN 1178
I +RFS PF +PV+ +A Y DV+ PMD +++ S G R++ +FL D+ +F N
Sbjct: 1355 IVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTN 1414
Query: 1179 AVMYNDSDHHVYHMAVE 1195
A +YN HV V+
Sbjct: 1415 AEVYNCRGSHVLSCMVK 1431
Score = 55.8 bits (133), Expect = 2e-07
Identities = 45/207 (21%), Positives = 87/207 (42%), Gaps = 13/207 (6%)
Query: 609 DSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESD 668
+S E+S + ++ E+EEE+ A P++ +G+ + PP + S
Sbjct: 1248 ESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVI-----PPAARSG 1302
Query: 669 DGFSIHNATLQSHTLADSIPSSPASSQFSVCS---EDQEAIQAQKIWKKAIMLVWRAAAN 725
+ H+ S P +P V + + + + Q + + +
Sbjct: 1303 -----RRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVK 1357
Query: 726 HRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVM 785
+R++ F +PVT D A Y+ ++ PMD T++ G RS EF D+ +F NA +
Sbjct: 1358 YRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEV 1417
Query: 786 YNSSDHDVYHMAVEMQRDVLEQIQQFL 812
YN V V+ ++ ++ + + L
Sbjct: 1418 YNCRGSHVLSCMVKTEQCLVALLHKHL 1444
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 59.3 bits (142), Expect = 2e-08
Identities = 30/66 (45%), Positives = 37/66 (56%)
Query: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 791
F PVTD IAPGY I++ PMD T+K I +S EF+ D LM NA+ YN D
Sbjct: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220
Query: 792 DVYHMA 797
Y +A
Sbjct: 221 VYYKLA 226
Score = 49.7 bits (117), Expect = 2e-05
Identities = 23/66 (34%), Positives = 36/66 (54%)
Query: 1128 FLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDH 1187
F PV++ APGY ++K PMD ++K + +++ +F D LM NA+ YN D
Sbjct: 161 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 220
Query: 1188 HVYHMA 1193
Y +A
Sbjct: 221 VYYKLA 226
>gi|242247075 bromodomain containing 9 isoform 2 [Homo sapiens]
Length = 544
Score = 59.3 bits (142), Expect = 2e-08
Identities = 30/66 (45%), Positives = 37/66 (56%)
Query: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 791
F PVTD IAPGY I++ PMD T+K I +S EF+ D LM NA+ YN D
Sbjct: 108 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 167
Query: 792 DVYHMA 797
Y +A
Sbjct: 168 VYYKLA 173
Score = 49.7 bits (117), Expect = 2e-05
Identities = 23/66 (34%), Positives = 36/66 (54%)
Query: 1128 FLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDH 1187
F PV++ APGY ++K PMD ++K + +++ +F D LM NA+ YN D
Sbjct: 108 FAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDT 167
Query: 1188 HVYHMA 1193
Y +A
Sbjct: 168 VYYKLA 173
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 58.9 bits (141), Expect = 3e-08
Identities = 27/78 (34%), Positives = 44/78 (56%)
Query: 1121 SHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAV 1180
SH + PFL+PV+ R GY+ ++K PMD ++++ L +G + +F D +L+F N
Sbjct: 1811 SHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQ 1870
Query: 1181 MYNDSDHHVYHMAVEMRR 1198
+N+ D V MRR
Sbjct: 1871 TFNEDDSEVGKAGHIMRR 1888
Score = 54.3 bits (129), Expect = 7e-07
Identities = 28/87 (32%), Positives = 46/87 (52%)
Query: 725 NHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAV 784
+H A FL+PV + GY I++ PMD ST+++ + G S+ EF D +L+F N
Sbjct: 1811 SHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQ 1870
Query: 785 MYNSSDHDVYHMAVEMQRDVLEQIQQF 811
+N D +V M+R + ++F
Sbjct: 1871 TFNEDDSEVGKAGHIMRRFFESRWEEF 1897
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 58.5 bits (140), Expect = 4e-08
Identities = 78/348 (22%), Positives = 134/348 (38%), Gaps = 62/348 (17%)
Query: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 791
F PV P Y+ ++ PMDL TI+KNI +S F D+ L+ N+V YN +
Sbjct: 1528 FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPES 1587
Query: 792 DVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMGS 851
A E+ + + ++ + + Q + +AK ++A + PM
Sbjct: 1588 QYTKTAQEIVNVCYQTLTEY--DEHLTQLEKDICTAK------EAALEEAELESLDPMTP 1639
Query: 852 PAFLLSLFMGHEWVWLDSEQDHPNDSELSNDCRSLFSSWDSSLDLDVGNWRETEDPEAEE 911
+ P +L + SL S D+S+ D N + P A
Sbjct: 1640 GPYT------------------PQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSATP 1681
Query: 912 LEESSPEREPSELLVGDGGSEESQEAARKASHQNLLHFLSEVAYLMEPLCISSNESSEGC 971
++ + E E GDG + +E + ++L+ E L +S E E
Sbjct: 1682 EKQVTQEGED-----GDGDLADEEEGTVQQPQASVLY---------EDLLMSEGEDDE-- 1725
Query: 972 CPPSGTRQEG----REIKASEGERELCRETEELSAKGDPLVAEKPLGENGKPEVASAPSV 1027
+G+ +EG I+ SE + ++ + G + L EN + ++ + S+
Sbjct: 1726 -EDAGSDEEGDNPFSAIQLSESGSD-----SDVGSGGIRPKQPRMLQENTRMDMENEESM 1779
Query: 1028 ICTVQGLLTESEEGEAQQESKG-EDQGEVYVSEMEDQPPSGECDDAFN 1074
+ S EG+ + S G ED Y S E P S D +F+
Sbjct: 1780 M---------SYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFS 1818
Score = 53.1 bits (126), Expect = 2e-06
Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 8/128 (6%)
Query: 1069 CDDAFNIKETPLVDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPF 1128
CD+ KE L A K + DD Q F + KM+A S PF
Sbjct: 1477 CDEKLKEKEDKL-------ARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD-SWPF 1528
Query: 1129 LKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHH 1188
PV+++ P Y V+ PMDL ++++N+SK + ++ FL D+ L+ N+V YN +
Sbjct: 1529 HHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1588
Query: 1189 VYHMAVEM 1196
A E+
Sbjct: 1589 YTKTAQEI 1596
Score = 50.1 bits (118), Expect = 1e-05
Identities = 22/69 (31%), Positives = 37/69 (53%)
Query: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 791
F PV + Y+ I+ RPMDL T+++N+ L S EF+ + L+ +N+ YN H
Sbjct: 1405 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1464
Query: 792 DVYHMAVEM 800
+ ++ M
Sbjct: 1465 SLTQISQSM 1473
Score = 43.9 bits (102), Expect = 0.001
Identities = 21/70 (30%), Positives = 36/70 (51%)
Query: 1127 PFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSD 1186
PF PV+ + Y ++ RPMDL +L+ N+ K + +F L L+ +N+ YN
Sbjct: 1404 PFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPK 1463
Query: 1187 HHVYHMAVEM 1196
H + ++ M
Sbjct: 1464 HSLTQISQSM 1473
Score = 35.8 bits (81), Expect = 0.26
Identities = 79/388 (20%), Positives = 147/388 (37%), Gaps = 58/388 (14%)
Query: 322 PAVSTTESVAPVSQPDNCVPMEAVGDP------HTVTVSMDSSEISMIINSIKEECFRSG 375
P + + VA DN V + + P H V +I+N + E R
Sbjct: 1497 PLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKN 1556
Query: 376 VAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDF-ETVGDIIAIIEDKVDDHPEVL 434
+++ S+ +D D+ + +V Y G E + +T +I+ + + ++ E L
Sbjct: 1557 ISKHKYQSRESFLD-----DVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHL 1611
Query: 435 D------VAAVEAALSFCE-ENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDF 487
A EAAL E E+ DP + PGP+ D L ++ ++ F
Sbjct: 1612 TQLEKDICTAKEAALEEAELESLDPMT-PGPYTPQPPDLYDTNTSL-----SMSRDASVF 1665
Query: 488 EETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEE 547
++ N + ++ P ++ E + + ++ E T +P ++ L E+
Sbjct: 1666 QDESNMSVLDIPSAT-PEKQVTQEGEDGDGDLADEE------EGTVQQP---QASVLYED 1715
Query: 548 LGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDP-LEAETQHKFE 606
L + GE E D + + P + ++ S S G P + L+ T+ E
Sbjct: 1716 L-LMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGSGGIRPKQPRMLQENTRMDME 1774
Query: 607 MSDSLK-------------EESGTIFGSQIKDAPGEDEEEDG--------VSEAASLEEP 645
+S+ E+S +GS + P + ++ VSE EE
Sbjct: 1775 NEESMMSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEE 1834
Query: 646 KEEDQGEGYLSEMDNEPPVSESDDGFSI 673
+E+ G LS++ +S+D SI
Sbjct: 1835 EEQRSGPSVLSQVHLSEDEEDSEDFHSI 1862
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 58.5 bits (140), Expect = 4e-08
Identities = 78/348 (22%), Positives = 134/348 (38%), Gaps = 62/348 (17%)
Query: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 791
F PV P Y+ ++ PMDL TI+KNI +S F D+ L+ N+V YN +
Sbjct: 1549 FHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPES 1608
Query: 792 DVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMGS 851
A E+ + + ++ + + Q + +AK ++A + PM
Sbjct: 1609 QYTKTAQEIVNVCYQTLTEY--DEHLTQLEKDICTAK------EAALEEAELESLDPMTP 1660
Query: 852 PAFLLSLFMGHEWVWLDSEQDHPNDSELSNDCRSLFSSWDSSLDLDVGNWRETEDPEAEE 911
+ P +L + SL S D+S+ D N + P A
Sbjct: 1661 GPYT------------------PQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSATP 1702
Query: 912 LEESSPEREPSELLVGDGGSEESQEAARKASHQNLLHFLSEVAYLMEPLCISSNESSEGC 971
++ + E E GDG + +E + ++L+ E L +S E E
Sbjct: 1703 EKQVTQEGED-----GDGDLADEEEGTVQQPQASVLY---------EDLLMSEGEDDE-- 1746
Query: 972 CPPSGTRQEG----REIKASEGERELCRETEELSAKGDPLVAEKPLGENGKPEVASAPSV 1027
+G+ +EG I+ SE + ++ + G + L EN + ++ + S+
Sbjct: 1747 -EDAGSDEEGDNPFSAIQLSESGSD-----SDVGSGGIRPKQPRMLQENTRMDMENEESM 1800
Query: 1028 ICTVQGLLTESEEGEAQQESKG-EDQGEVYVSEMEDQPPSGECDDAFN 1074
+ S EG+ + S G ED Y S E P S D +F+
Sbjct: 1801 M---------SYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFS 1839
Score = 53.1 bits (126), Expect = 2e-06
Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 8/128 (6%)
Query: 1069 CDDAFNIKETPLVDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPF 1128
CD+ KE L A K + DD Q F + KM+A S PF
Sbjct: 1498 CDEKLKEKEDKL-------ARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD-SWPF 1549
Query: 1129 LKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHH 1188
PV+++ P Y V+ PMDL ++++N+SK + ++ FL D+ L+ N+V YN +
Sbjct: 1550 HHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1609
Query: 1189 VYHMAVEM 1196
A E+
Sbjct: 1610 YTKTAQEI 1617
Score = 50.1 bits (118), Expect = 1e-05
Identities = 22/69 (31%), Positives = 37/69 (53%)
Query: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDH 791
F PV + Y+ I+ RPMDL T+++N+ L S EF+ + L+ +N+ YN H
Sbjct: 1426 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKH 1485
Query: 792 DVYHMAVEM 800
+ ++ M
Sbjct: 1486 SLTQISQSM 1494
Score = 43.9 bits (102), Expect = 0.001
Identities = 21/70 (30%), Positives = 36/70 (51%)
Query: 1127 PFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSD 1186
PF PV+ + Y ++ RPMDL +L+ N+ K + +F L L+ +N+ YN
Sbjct: 1425 PFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPK 1484
Query: 1187 HHVYHMAVEM 1196
H + ++ M
Sbjct: 1485 HSLTQISQSM 1494
Score = 35.8 bits (81), Expect = 0.26
Identities = 79/388 (20%), Positives = 147/388 (37%), Gaps = 58/388 (14%)
Query: 322 PAVSTTESVAPVSQPDNCVPMEAVGDP------HTVTVSMDSSEISMIINSIKEECFRSG 375
P + + VA DN V + + P H V +I+N + E R
Sbjct: 1518 PLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKN 1577
Query: 376 VAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDF-ETVGDIIAIIEDKVDDHPEVL 434
+++ S+ +D D+ + +V Y G E + +T +I+ + + ++ E L
Sbjct: 1578 ISKHKYQSRESFLD-----DVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHL 1632
Query: 435 D------VAAVEAALSFCE-ENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDF 487
A EAAL E E+ DP + PGP+ D L ++ ++ F
Sbjct: 1633 TQLEKDICTAKEAALEEAELESLDPMT-PGPYTPQPPDLYDTNTSL-----SMSRDASVF 1686
Query: 488 EETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEE 547
++ N + ++ P ++ E + + ++ E T +P ++ L E+
Sbjct: 1687 QDESNMSVLDIPSAT-PEKQVTQEGEDGDGDLADEE------EGTVQQP---QASVLYED 1736
Query: 548 LGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDP-LEAETQHKFE 606
L + GE E D + + P + ++ S S G P + L+ T+ E
Sbjct: 1737 L-LMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGSGGIRPKQPRMLQENTRMDME 1795
Query: 607 MSDSLK-------------EESGTIFGSQIKDAPGEDEEEDG--------VSEAASLEEP 645
+S+ E+S +GS + P + ++ VSE EE
Sbjct: 1796 NEESMMSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEE 1855
Query: 646 KEEDQGEGYLSEMDNEPPVSESDDGFSI 673
+E+ G LS++ +S+D SI
Sbjct: 1856 EEQRSGPSVLSQVHLSEDEEDSEDFHSI 1883
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 58.2 bits (139), Expect = 5e-08
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 707 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 763
Q Q + K + +W+ H ++ F +PV D + P Y++I++ PMDL+TIKK +EN
Sbjct: 31 QLQYLQKVVLKDLWK----HSFSWPFQRPV-DAVKLQLPDYYTIIKNPMDLNTIKKRLEN 85
Query: 764 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSE 822
+E D MF N +YN D+ MA +++ ++++ Q + ++ E
Sbjct: 86 KYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKE 144
Score = 57.0 bits (136), Expect = 1e-07
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 722 AAANHRYANVFLQPVTDDIAPG---YHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIML 778
A + YA F PV D A G Y+ +V+ PMDL TIK+ ++N + +F D+ L
Sbjct: 285 AKKHFSYAWPFYNPV-DVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRL 343
Query: 779 MFQNAVMYNSSDHDVYHMAVEMQRDVLE 806
MF N YN DH+V MA M +DV E
Sbjct: 344 MFMNCYKYNPPDHEVVTMA-RMLQDVFE 370
Score = 56.6 bits (135), Expect = 1e-07
Identities = 59/211 (27%), Positives = 82/211 (38%), Gaps = 13/211 (6%)
Query: 1003 KGDPLVAEKPLGENGKPEVASAPSV--ICTVQGLLTESEEGEAQQESKG-EDQGEVYVSE 1059
K P EK + P V S+ + VQG S A Q +KG + + +
Sbjct: 162 KSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPA 221
Query: 1060 MEDQPPSGECDDAFNIKETPLVDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLP----V 1115
S E F K L + + + L D Q V + + L +
Sbjct: 222 TSAVKASSEFSPTFTEKSVAL-PPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEIL 280
Query: 1116 WKMIASHRFSS--PFLKPVSERQAP--GYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRD 1171
+M+A FS PF PV Y DVVK PMDL ++K + + +F D
Sbjct: 281 KEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAAD 340
Query: 1172 LMLMFQNAVMYNDSDHHVYHMAVEMRREVLE 1202
+ LMF N YN DH V MA M ++V E
Sbjct: 341 VRLMFMNCYKYNPPDHEVVTMA-RMLQDVFE 370
Score = 53.9 bits (128), Expect = 9e-07
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
Query: 1107 LFKKTLLPVWKMIASHRFSSPFLKPVS--ERQAPGYKDVVKRPMDLTSLKRNLSKGRIRT 1164
L K L +WK H FS PF +PV + Q P Y ++K PMDL ++K+ L
Sbjct: 35 LQKVVLKDLWK----HSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAK 90
Query: 1165 MAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQI 1204
++ + D MF N +YN + MA + + ++++
Sbjct: 91 ASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKL 130
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 58.2 bits (139), Expect = 5e-08
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 707 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 763
Q Q + K + +W+ H ++ F +PV D + P Y++I++ PMDL+TIKK +EN
Sbjct: 31 QLQYLQKVVLKDLWK----HSFSWPFQRPV-DAVKLQLPDYYTIIKNPMDLNTIKKRLEN 85
Query: 764 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSE 822
+E D MF N +YN D+ MA +++ ++++ Q + ++ E
Sbjct: 86 KYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKE 144
Score = 57.0 bits (136), Expect = 1e-07
Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 722 AAANHRYANVFLQPVTDDIAPG---YHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIML 778
A + YA F PV D A G Y+ +V+ PMDL TIK+ ++N + +F D+ L
Sbjct: 285 AKKHFSYAWPFYNPV-DVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRL 343
Query: 779 MFQNAVMYNSSDHDVYHMAVEMQRDVLE 806
MF N YN DH+V MA M +DV E
Sbjct: 344 MFMNCYKYNPPDHEVVTMA-RMLQDVFE 370
Score = 56.6 bits (135), Expect = 1e-07
Identities = 59/211 (27%), Positives = 82/211 (38%), Gaps = 13/211 (6%)
Query: 1003 KGDPLVAEKPLGENGKPEVASAPSV--ICTVQGLLTESEEGEAQQESKG-EDQGEVYVSE 1059
K P EK + P V S+ + VQG S A Q +KG + + +
Sbjct: 162 KSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPA 221
Query: 1060 MEDQPPSGECDDAFNIKETPLVDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLP----V 1115
S E F K L + + + L D Q V + + L +
Sbjct: 222 TSAVKASSEFSPTFTEKSVAL-PPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEIL 280
Query: 1116 WKMIASHRFSS--PFLKPVSERQAP--GYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRD 1171
+M+A FS PF PV Y DVVK PMDL ++K + + +F D
Sbjct: 281 KEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAAD 340
Query: 1172 LMLMFQNAVMYNDSDHHVYHMAVEMRREVLE 1202
+ LMF N YN DH V MA M ++V E
Sbjct: 341 VRLMFMNCYKYNPPDHEVVTMA-RMLQDVFE 370
Score = 53.9 bits (128), Expect = 9e-07
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
Query: 1107 LFKKTLLPVWKMIASHRFSSPFLKPVS--ERQAPGYKDVVKRPMDLTSLKRNLSKGRIRT 1164
L K L +WK H FS PF +PV + Q P Y ++K PMDL ++K+ L
Sbjct: 35 LQKVVLKDLWK----HSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAK 90
Query: 1165 MAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRREVLEQI 1204
++ + D MF N +YN + MA + + ++++
Sbjct: 91 ASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKL 130
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 57.4 bits (137), Expect = 8e-08
Identities = 27/83 (32%), Positives = 44/83 (53%)
Query: 1111 TLLPVWKMIASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLR 1170
TL + + + SH+ + PF++PV +APGY +V++ PMDL ++ L + F+
Sbjct: 731 TLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMA 790
Query: 1171 DLMLMFQNAVMYNDSDHHVYHMA 1193
DL +F N YN + Y A
Sbjct: 791 DLQRVFTNCKEYNPPESEYYKCA 813
Score = 52.8 bits (125), Expect = 2e-06
Identities = 25/86 (29%), Positives = 47/86 (54%)
Query: 725 NHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAV 784
+H+ A F++PV APGY+ +++ PMDL T+ + ++N S F D+ +F N
Sbjct: 741 SHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCK 800
Query: 785 MYNSSDHDVYHMAVEMQRDVLEQIQQ 810
YN + + Y A +++ +I++
Sbjct: 801 EYNPPESEYYKCANILEKFFFSKIKE 826
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
sapiens]
Length = 1205
Score = 57.0 bits (136), Expect = 1e-07
Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Query: 729 ANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNS 788
A++F +PV P Y + +PMD ST+++ +E+ L R+ EF+ D L+ N + YN+
Sbjct: 611 AHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNA 670
Query: 789 SDHDVYHMAVEMQRDV 804
D ++H A RD+
Sbjct: 671 KD-TIFHRAAVRLRDL 685
Score = 49.7 bits (117), Expect = 2e-05
Identities = 22/70 (31%), Positives = 38/70 (54%)
Query: 1128 FLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDH 1187
F +PV+ + P Y + + +PMD ++++R L RT+ +F D L+ N + YN D
Sbjct: 614 FAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDT 673
Query: 1188 HVYHMAVEMR 1197
+ AV +R
Sbjct: 674 IFHRAAVRLR 683
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 53.5 bits (127), Expect = 1e-06
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 12/137 (8%)
Query: 720 WRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLM 779
++ ++ + + VF+Q + P Y+ ++++P+D IK+ I N RS + ++D+ML+
Sbjct: 1397 YKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLL 1456
Query: 780 FQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQ-----------TSESGISAK 828
NA +N +Y ++ +Q V + +Q +A + + ES AK
Sbjct: 1457 CHNAQTFNLEGSQIYEDSIVLQ-SVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAK 1515
Query: 829 SLRGRDSTRKQDASEKD 845
S++ + K+D +D
Sbjct: 1516 SVKVKIKLNKKDDKGRD 1532
Score = 43.9 bits (102), Expect = 0.001
Identities = 17/82 (20%), Positives = 44/82 (53%)
Query: 1116 WKMIASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLM 1175
+K + + S F++ S ++ P Y +++++P+D +K + + R++ +D+ML+
Sbjct: 1397 YKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLL 1456
Query: 1176 FQNAVMYNDSDHHVYHMAVEMR 1197
NA +N +Y ++ ++
Sbjct: 1457 CHNAQTFNLEGSQIYEDSIVLQ 1478
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 53.1 bits (126), Expect = 2e-06
Identities = 60/289 (20%), Positives = 121/289 (41%), Gaps = 32/289 (11%)
Query: 567 DETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEM--SDSLKEESGTIFGSQIK 624
DE P +K +A E + E ++H+ E+ SDSL E+ I+
Sbjct: 1308 DELPSWIIKDDAEVERLTCEEEE----EKMFGRGSRHRKEVDYSDSLTEKQWLKTLKAIE 1363
Query: 625 DAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLA 684
+ E+ EE+ + +S + ++ D G S + DD + A
Sbjct: 1364 EGTLEEIEEEVRQKKSSRKRKRDSDAGS---STPTTSTRSRDKDD--ESKKQKKRGRPPA 1418
Query: 685 DSIPSSPASSQFSVCSEDQEAIQAQKIWKKAI--MLVWRAAANHRYANVFLQPVTDDIAP 742
+ + +P + K KK + ++ ++ ++ + + VF+Q + P
Sbjct: 1419 EKLSPNPPN--------------LTKKMKKIVDAVIKYKDSSGRQLSEVFIQLPSRKELP 1464
Query: 743 GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 802
Y+ ++++P+D IK+ I N RS + ++D+ML+ QNA +N +Y ++ +Q
Sbjct: 1465 EYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQ- 1523
Query: 803 DVLEQIQQFLATQLIMQTSESGISAKSLRG-RDSTRKQDASEKDSVPMG 850
V ++Q + + SE S + G + + + S K + +G
Sbjct: 1524 SVFTSVRQKIEKE---DDSEGEESEEEEEGEEEGSESESRSVKVKIKLG 1569
Score = 44.7 bits (104), Expect = 6e-04
Identities = 24/117 (20%), Positives = 56/117 (47%), Gaps = 7/117 (5%)
Query: 1116 WKMIASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLM 1175
+K + + S F++ S ++ P Y +++++P+D +K + + R++ +D+ML+
Sbjct: 1442 YKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLL 1501
Query: 1176 FQNAVMYNDSDHHVYHMAVEMRREVLEQIQVLNIWLDKRKGSSSLEGEPANPVDDGK 1232
QNA +N +Y ++ ++ V K + EGE + ++G+
Sbjct: 1502 CQNAQTFNLEGSLIYEDSIVLQ-------SVFTSVRQKIEKEDDSEGEESEEEEEGE 1551
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/65 (36%), Positives = 39/65 (60%)
Query: 1119 IASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQN 1178
+ H S PFLK VS+ Q P Y D++K+P+ L ++ ++K + ++F+ D+ LMF N
Sbjct: 1413 LVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSN 1472
Query: 1179 AVMYN 1183
YN
Sbjct: 1473 CFEYN 1477
Score = 39.3 bits (90), Expect = 0.023
Identities = 19/56 (33%), Positives = 32/56 (57%)
Query: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYN 787
FL+ V+ P Y+ I+++P+ L+ I++ + + +EF DI LMF N YN
Sbjct: 1422 FLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1477
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/65 (36%), Positives = 39/65 (60%)
Query: 1119 IASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQN 1178
+ H S PFLK VS+ Q P Y D++K+P+ L ++ ++K + ++F+ D+ LMF N
Sbjct: 1445 LVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSN 1504
Query: 1179 AVMYN 1183
YN
Sbjct: 1505 CFEYN 1509
Score = 39.3 bits (90), Expect = 0.023
Identities = 19/56 (33%), Positives = 32/56 (57%)
Query: 732 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYN 787
FL+ V+ P Y+ I+++P+ L+ I++ + + +EF DI LMF N YN
Sbjct: 1454 FLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,746,993
Number of Sequences: 37866
Number of extensions: 2666606
Number of successful extensions: 14225
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 499
Number of HSP's that attempted gapping in prelim test: 11188
Number of HSP's gapped (non-prelim): 2846
length of query: 1235
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1121
effective length of database: 13,930,794
effective search space: 15616420074
effective search space used: 15616420074
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.