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Search of human proteins with 34452686
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34452686 ring finger protein, LIM domain interacting [Homo
sapiens]
(624 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34452686 ring finger protein, LIM domain interacting [Homo sa... 1230 0.0
gi|34452684 ring finger protein, LIM domain interacting [Homo sa... 1230 0.0
gi|5174653 ring finger protein 6 [Homo sapiens] 427 e-119
gi|34305295 ring finger protein 6 [Homo sapiens] 427 e-119
gi|34305293 ring finger protein 6 [Homo sapiens] 427 e-119
gi|34577087 ring finger protein 13 [Homo sapiens] 79 1e-14
gi|6005864 ring finger protein 13 [Homo sapiens] 79 1e-14
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 79 2e-14
gi|14149702 ring finger protein 167 [Homo sapiens] 77 4e-14
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 74 4e-13
gi|37577185 ring finger protein 38 isoform 2 [Homo sapiens] 74 5e-13
gi|37577181 ring finger protein 38 isoform 2 [Homo sapiens] 74 5e-13
gi|37577179 ring finger protein 38 isoform 3 [Homo sapiens] 74 5e-13
gi|37577177 ring finger protein 38 isoform 2 [Homo sapiens] 74 5e-13
gi|37577175 ring finger protein 38 isoform 1 [Homo sapiens] 74 5e-13
gi|7662486 ring finger protein 44 [Homo sapiens] 73 9e-13
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 72 2e-12
gi|161016767 mucin 21 [Homo sapiens] 65 1e-10
gi|57864582 hornerin [Homo sapiens] 65 2e-10
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 65 2e-10
gi|150170725 zinc and ring finger 4 [Homo sapiens] 64 3e-10
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 64 4e-10
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 64 4e-10
gi|60097902 filaggrin [Homo sapiens] 63 9e-10
gi|29788758 ring finger protein 130 [Homo sapiens] 63 9e-10
gi|150378447 zinc and ring finger 3 [Homo sapiens] 62 1e-09
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 61 3e-09
gi|37595553 ring finger protein 111 [Homo sapiens] 61 3e-09
gi|58331204 ring finger protein 150 [Homo sapiens] 61 4e-09
gi|56711322 ring finger protein 43 [Homo sapiens] 60 5e-09
>gi|34452686 ring finger protein, LIM domain interacting [Homo
sapiens]
Length = 624
Score = 1230 bits (3182), Expect = 0.0
Identities = 624/624 (100%), Positives = 624/624 (100%)
Query: 1 MENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEST 60
MENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEST
Sbjct: 1 MENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEST 60
Query: 61 EEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQ 120
EEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQ
Sbjct: 61 EEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQ 120
Query: 121 SWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPR 180
SWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPR
Sbjct: 121 SWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPR 180
Query: 181 SESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPR 240
SESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPR
Sbjct: 181 SESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPR 240
Query: 241 RSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS 300
RSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS
Sbjct: 241 RSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS 300
Query: 301 SDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESER 360
SDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESER
Sbjct: 301 SDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESER 360
Query: 361 GGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFM 420
GGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFM
Sbjct: 361 GGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFM 420
Query: 421 YSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSS 480
YSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSS
Sbjct: 421 YSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSS 480
Query: 481 SGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNED 540
SGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNED
Sbjct: 481 SGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNED 540
Query: 541 DDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRW 600
DDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRW
Sbjct: 541 DDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRW 600
Query: 601 LSENSTCPICRRAVLASGNRESVV 624
LSENSTCPICRRAVLASGNRESVV
Sbjct: 601 LSENSTCPICRRAVLASGNRESVV 624
>gi|34452684 ring finger protein, LIM domain interacting [Homo
sapiens]
Length = 624
Score = 1230 bits (3182), Expect = 0.0
Identities = 624/624 (100%), Positives = 624/624 (100%)
Query: 1 MENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEST 60
MENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEST
Sbjct: 1 MENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEST 60
Query: 61 EEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQ 120
EEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQ
Sbjct: 61 EEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQ 120
Query: 121 SWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPR 180
SWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPR
Sbjct: 121 SWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPR 180
Query: 181 SESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPR 240
SESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPR
Sbjct: 181 SESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPR 240
Query: 241 RSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS 300
RSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS
Sbjct: 241 RSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS 300
Query: 301 SDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESER 360
SDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESER
Sbjct: 301 SDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESER 360
Query: 361 GGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFM 420
GGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFM
Sbjct: 361 GGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFM 420
Query: 421 YSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSS 480
YSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSS
Sbjct: 421 YSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSS 480
Query: 481 SGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNED 540
SGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNED
Sbjct: 481 SGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNED 540
Query: 541 DDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRW 600
DDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRW
Sbjct: 541 DDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRW 600
Query: 601 LSENSTCPICRRAVLASGNRESVV 624
LSENSTCPICRRAVLASGNRESVV
Sbjct: 601 LSENSTCPICRRAVLASGNRESVV 624
>gi|5174653 ring finger protein 6 [Homo sapiens]
Length = 685
Score = 427 bits (1097), Expect = e-119
Identities = 286/704 (40%), Positives = 372/704 (52%), Gaps = 112/704 (15%)
Query: 1 MENSDSNDKGSGDQSAAQ--------RRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNL 52
M S S G +++ Q RR Q +RL REEA+YQF+N L++EDYRLMRD+NL
Sbjct: 1 MNQSRSRSDGGSEETLPQDHNHHENERRWQQERLHREEAYYQFINELNDEDYRLMRDHNL 60
Query: 53 LGTPGESTEEELLRRLQQIKEG----PPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQT 108
LGTPGE T EEL +RL +KE P ++ R + + S+ DS+++WLN+ R+T
Sbjct: 61 LGTPGEITSEELQQRLDGVKEQLASQPDLRDGTNYRDSEVPRESSHEDSLLEWLNTFRRT 120
Query: 109 GNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVN----------------------RN 146
GN TRSGQ GNQ+WRAVSRTNPN+G+FRFSLEI+VN R+
Sbjct: 121 GNATRSGQNGNQTWRAVSRTNPNNGEFRFSLEIHVNHENRGFEIHGEDYTDIPLSDSNRD 180
Query: 147 NGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTS--------------------- 185
+ + + P ARR+ + N + PR+ S
Sbjct: 181 HTANRQQRSTSPVARRTRSQTSVNFNGSSSNIPRTRLASRGQNPAEGSFSTLGRLRNGIG 240
Query: 186 ----------ARPSRSERNSTEALTEVPPTRGQRRARSRSPDH--------RRTRARAE- 226
+R + S + +E+ GQR + ++ R T R E
Sbjct: 241 GAAGIPRANASRTNFSSHTNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEP 300
Query: 227 ---RSRSPLHPMSEIPRRS---HHSISSQTFEHPLVNETEGSSRTRHHVTL-RQQISGPE 279
RS S S I R+S +H+ SQ P+ T S R R + +Q E
Sbjct: 301 IRLRSTSNSRSRSPIQRQSGTVYHN--SQRESRPVQQTTRRSVRRRGRTRVFLEQDRERE 358
Query: 280 LLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSI 339
S +R S+ +S ST +R PTI LDLQVRR+RPGE R RDSI
Sbjct: 359 RRGTAYTPFSNSRLVSRITVEEGEESSRSSTAV-RRHPTITLDLQVRRIRPGENRDRDSI 417
Query: 340 ASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTS 399
A+RTRSR NTVT ES GGFRRT SR ER+G+RTYVSTI +P+RRI L E +S
Sbjct: 418 ANRTRSRVGLAENTVTIESNSGGFRRTISRLERSGIRTYVSTITVPLRRISENELVEPSS 477
Query: 400 VAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSS 459
VA++++LRQIMTGFGELS M +DS+SE RN + S
Sbjct: 478 VALRSILRQIMTGFGELSSLMEADSESE-----LQRNGQHLPDMH------------SEL 520
Query: 460 SSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRH-RAPV 518
S+ + ++ S SS + G+S+E G NE + + R GR R P
Sbjct: 521 SNLGTDNNRSQHREGSSQDRQAQGDSTE-----MHGENETTQPHTRNSDSRGGRQLRNPN 575
Query: 519 TFDESGSLPFLSLAQFFLLNE-DDDDQPRGLTKEQIDNLAMRSFGEN----DALKTCSVC 573
E+G+LP L LA FFLLNE DDDD+ RGLTKEQIDNL+ R + N + K CSVC
Sbjct: 576 NLVETGTLPILRLAHFFLLNESDDDDRIRGLTKEQIDNLSTRHYEHNSIDSELGKICSVC 635
Query: 574 ITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLAS 617
I++Y GNKLR+LPC HE+H+HCIDRWLSEN TCPICR+ VL S
Sbjct: 636 ISDYVTGNKLRQLPCMHEFHIHCIDRWLSENCTCPICRQPVLGS 679
>gi|34305295 ring finger protein 6 [Homo sapiens]
Length = 685
Score = 427 bits (1097), Expect = e-119
Identities = 286/704 (40%), Positives = 372/704 (52%), Gaps = 112/704 (15%)
Query: 1 MENSDSNDKGSGDQSAAQ--------RRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNL 52
M S S G +++ Q RR Q +RL REEA+YQF+N L++EDYRLMRD+NL
Sbjct: 1 MNQSRSRSDGGSEETLPQDHNHHENERRWQQERLHREEAYYQFINELNDEDYRLMRDHNL 60
Query: 53 LGTPGESTEEELLRRLQQIKEG----PPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQT 108
LGTPGE T EEL +RL +KE P ++ R + + S+ DS+++WLN+ R+T
Sbjct: 61 LGTPGEITSEELQQRLDGVKEQLASQPDLRDGTNYRDSEVPRESSHEDSLLEWLNTFRRT 120
Query: 109 GNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVN----------------------RN 146
GN TRSGQ GNQ+WRAVSRTNPN+G+FRFSLEI+VN R+
Sbjct: 121 GNATRSGQNGNQTWRAVSRTNPNNGEFRFSLEIHVNHENRGFEIHGEDYTDIPLSDSNRD 180
Query: 147 NGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTS--------------------- 185
+ + + P ARR+ + N + PR+ S
Sbjct: 181 HTANRQQRSTSPVARRTRSQTSVNFNGSSSNIPRTRLASRGQNPAEGSFSTLGRLRNGIG 240
Query: 186 ----------ARPSRSERNSTEALTEVPPTRGQRRARSRSPDH--------RRTRARAE- 226
+R + S + +E+ GQR + ++ R T R E
Sbjct: 241 GAAGIPRANASRTNFSSHTNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEP 300
Query: 227 ---RSRSPLHPMSEIPRRS---HHSISSQTFEHPLVNETEGSSRTRHHVTL-RQQISGPE 279
RS S S I R+S +H+ SQ P+ T S R R + +Q E
Sbjct: 301 IRLRSTSNSRSRSPIQRQSGTVYHN--SQRESRPVQQTTRRSVRRRGRTRVFLEQDRERE 358
Query: 280 LLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSI 339
S +R S+ +S ST +R PTI LDLQVRR+RPGE R RDSI
Sbjct: 359 RRGTAYTPFSNSRLVSRITVEEGEESSRSSTAV-RRHPTITLDLQVRRIRPGENRDRDSI 417
Query: 340 ASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTS 399
A+RTRSR NTVT ES GGFRRT SR ER+G+RTYVSTI +P+RRI L E +S
Sbjct: 418 ANRTRSRVGLAENTVTIESNSGGFRRTISRLERSGIRTYVSTITVPLRRISENELVEPSS 477
Query: 400 VAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSS 459
VA++++LRQIMTGFGELS M +DS+SE RN + S
Sbjct: 478 VALRSILRQIMTGFGELSSLMEADSESE-----LQRNGQHLPDMH------------SEL 520
Query: 460 SSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRH-RAPV 518
S+ + ++ S SS + G+S+E G NE + + R GR R P
Sbjct: 521 SNLGTDNNRSQHREGSSQDRQAQGDSTE-----MHGENETTQPHTRNSDSRGGRQLRNPN 575
Query: 519 TFDESGSLPFLSLAQFFLLNE-DDDDQPRGLTKEQIDNLAMRSFGEN----DALKTCSVC 573
E+G+LP L LA FFLLNE DDDD+ RGLTKEQIDNL+ R + N + K CSVC
Sbjct: 576 NLVETGTLPILRLAHFFLLNESDDDDRIRGLTKEQIDNLSTRHYEHNSIDSELGKICSVC 635
Query: 574 ITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLAS 617
I++Y GNKLR+LPC HE+H+HCIDRWLSEN TCPICR+ VL S
Sbjct: 636 ISDYVTGNKLRQLPCMHEFHIHCIDRWLSENCTCPICRQPVLGS 679
>gi|34305293 ring finger protein 6 [Homo sapiens]
Length = 685
Score = 427 bits (1097), Expect = e-119
Identities = 286/704 (40%), Positives = 372/704 (52%), Gaps = 112/704 (15%)
Query: 1 MENSDSNDKGSGDQSAAQ--------RRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNL 52
M S S G +++ Q RR Q +RL REEA+YQF+N L++EDYRLMRD+NL
Sbjct: 1 MNQSRSRSDGGSEETLPQDHNHHENERRWQQERLHREEAYYQFINELNDEDYRLMRDHNL 60
Query: 53 LGTPGESTEEELLRRLQQIKEG----PPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQT 108
LGTPGE T EEL +RL +KE P ++ R + + S+ DS+++WLN+ R+T
Sbjct: 61 LGTPGEITSEELQQRLDGVKEQLASQPDLRDGTNYRDSEVPRESSHEDSLLEWLNTFRRT 120
Query: 109 GNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVN----------------------RN 146
GN TRSGQ GNQ+WRAVSRTNPN+G+FRFSLEI+VN R+
Sbjct: 121 GNATRSGQNGNQTWRAVSRTNPNNGEFRFSLEIHVNHENRGFEIHGEDYTDIPLSDSNRD 180
Query: 147 NGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTS--------------------- 185
+ + + P ARR+ + N + PR+ S
Sbjct: 181 HTANRQQRSTSPVARRTRSQTSVNFNGSSSNIPRTRLASRGQNPAEGSFSTLGRLRNGIG 240
Query: 186 ----------ARPSRSERNSTEALTEVPPTRGQRRARSRSPDH--------RRTRARAE- 226
+R + S + +E+ GQR + ++ R T R E
Sbjct: 241 GAAGIPRANASRTNFSSHTNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEP 300
Query: 227 ---RSRSPLHPMSEIPRRS---HHSISSQTFEHPLVNETEGSSRTRHHVTL-RQQISGPE 279
RS S S I R+S +H+ SQ P+ T S R R + +Q E
Sbjct: 301 IRLRSTSNSRSRSPIQRQSGTVYHN--SQRESRPVQQTTRRSVRRRGRTRVFLEQDRERE 358
Query: 280 LLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSI 339
S +R S+ +S ST +R PTI LDLQVRR+RPGE R RDSI
Sbjct: 359 RRGTAYTPFSNSRLVSRITVEEGEESSRSSTAV-RRHPTITLDLQVRRIRPGENRDRDSI 417
Query: 340 ASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTS 399
A+RTRSR NTVT ES GGFRRT SR ER+G+RTYVSTI +P+RRI L E +S
Sbjct: 418 ANRTRSRVGLAENTVTIESNSGGFRRTISRLERSGIRTYVSTITVPLRRISENELVEPSS 477
Query: 400 VAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSS 459
VA++++LRQIMTGFGELS M +DS+SE RN + S
Sbjct: 478 VALRSILRQIMTGFGELSSLMEADSESE-----LQRNGQHLPDMH------------SEL 520
Query: 460 SSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRH-RAPV 518
S+ + ++ S SS + G+S+E G NE + + R GR R P
Sbjct: 521 SNLGTDNNRSQHREGSSQDRQAQGDSTE-----MHGENETTQPHTRNSDSRGGRQLRNPN 575
Query: 519 TFDESGSLPFLSLAQFFLLNE-DDDDQPRGLTKEQIDNLAMRSFGEN----DALKTCSVC 573
E+G+LP L LA FFLLNE DDDD+ RGLTKEQIDNL+ R + N + K CSVC
Sbjct: 576 NLVETGTLPILRLAHFFLLNESDDDDRIRGLTKEQIDNLSTRHYEHNSIDSELGKICSVC 635
Query: 574 ITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLAS 617
I++Y GNKLR+LPC HE+H+HCIDRWLSEN TCPICR+ VL S
Sbjct: 636 ISDYVTGNKLRQLPCMHEFHIHCIDRWLSENCTCPICRQPVLGS 679
>gi|34577087 ring finger protein 13 [Homo sapiens]
Length = 381
Score = 79.0 bits (193), Expect = 1e-14
Identities = 36/94 (38%), Positives = 56/94 (59%), Gaps = 5/94 (5%)
Query: 529 LSLAQFFLLNEDDDDQPRG----LTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLR 584
L L F++ + D+ R L K+Q+ L + F + D C++C+ EY +G+KLR
Sbjct: 195 LILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLR 254
Query: 585 KLPCSHEYHVHCIDRWLSE-NSTCPICRRAVLAS 617
LPCSH YH C+D WL++ TCP+C++ V+ S
Sbjct: 255 ILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPS 288
>gi|6005864 ring finger protein 13 [Homo sapiens]
Length = 381
Score = 79.0 bits (193), Expect = 1e-14
Identities = 36/94 (38%), Positives = 56/94 (59%), Gaps = 5/94 (5%)
Query: 529 LSLAQFFLLNEDDDDQPRG----LTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLR 584
L L F++ + D+ R L K+Q+ L + F + D C++C+ EY +G+KLR
Sbjct: 195 LILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLR 254
Query: 585 KLPCSHEYHVHCIDRWLSE-NSTCPICRRAVLAS 617
LPCSH YH C+D WL++ TCP+C++ V+ S
Sbjct: 255 ILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPS 288
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 78.6 bits (192), Expect = 2e-14
Identities = 109/511 (21%), Positives = 194/511 (37%), Gaps = 32/511 (6%)
Query: 2 ENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTE 61
E+SDS+D D S + S + D + + N+ D D++ S++
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSS-----NSSDSSDSSNSSDSSDSSDSSNSSD 754
Query: 62 EELLRRLQQIKEGPPPQNSDENRGGDSSD--DVSNGDSIIDWLNSVRQTGNTTRSGQRGN 119
+SD + DSSD D SN D NS + +++ S N
Sbjct: 755 SS--------DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS-SDSSDSSNSSDSSN 805
Query: 120 QSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPS----ARRSSGENVENNSQRQ 175
S + S + +S S N + ++ S NS + ++ S S N ++S
Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865
Query: 176 VENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPM 235
+ S+S+++ S +S E+ + + S S D + ++ S S
Sbjct: 866 DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS--SDS 923
Query: 236 SEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNAS 295
SE S +S SS + +++ SS + + + +S + N+S
Sbjct: 924 SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983
Query: 296 QGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVT 355
+ SSD++ S +S+ S + S +S + + S + N++ +
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDS----------SDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 356 YESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGE 415
+S S S + + S ++ S+++ + +
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 416 LSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSS 475
SDS S S+ + + ++S + S SS SS SS+SS SS SS SS S
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Query: 476 SPSSSSGGESSETSSDLFEGSNEGSSSSGSS 506
S SS S S + S S++ S+SS SS
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184
Score = 78.2 bits (191), Expect = 2e-14
Identities = 113/523 (21%), Positives = 190/523 (36%), Gaps = 10/523 (1%)
Query: 3 NSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEE 62
+SDS+D D S + S D D + + ++ + D++ +S++
Sbjct: 560 SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS 619
Query: 63 ELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSW 122
+ E +SD + DSSD S+ S + + N++ S + S
Sbjct: 620 SDSKSDSSKSES---DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Query: 123 RAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSE 182
+ S + NS D S + + N + S +S++ + S+ S N N+S N
Sbjct: 677 SSSSSDSSNSSDSSDSSD-SSNSSESSDSSDSSDSDSSDSSDSSN-SNSSDSDSSNSSDS 734
Query: 183 STSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRS 242
S S+ S S +S + + S S D + ++ S S S+ S
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-----SDSNDSS 789
Query: 243 HHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSD 302
+ S SS + + + SS + S S +S + ++S + SSD
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849
Query: 303 TAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGG 362
+ S S S + D DS S S S +N+ +S
Sbjct: 850 GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909
Query: 363 FRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYS 422
S S + + S ++ S+++ + + + S
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969
Query: 423 DSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSG 482
DS+S + SN + S S SS+ S SS SS SS SS+SS SS+ S SS
Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029
Query: 483 GESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGS 525
S SSD + S+ SS S + + + D S S
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072
Score = 76.6 bits (187), Expect = 6e-14
Identities = 100/456 (21%), Positives = 178/456 (39%), Gaps = 77/456 (16%)
Query: 73 EGPPPQNSDENRGGDSSDDVSNGDSIIDW---LNSVRQTGNTTRSGQRGNQSWRAVSRTN 129
+G P +SDE+ G D ++ S+ +S NS N S +G + + S ++
Sbjct: 461 QGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSD 520
Query: 130 PNSGDFRFSLEINVNRNNGSQNSE-------------------NENEPSARRSSGENVEN 170
N+ D N N NNG+ +++ + + S+ S ++ ++
Sbjct: 521 TNNSDS------NGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574
Query: 171 NSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRS 230
NS ++ S+S+ + S S +S + + S S D + +++E S
Sbjct: 575 NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634
Query: 231 PLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASG 290
S+ S S SS + ++ +++ SS + S S ++S
Sbjct: 635 DSDSKSD----SSDSNSSDSSDNSDSSDSSNSSNSSD--------SSDSSDSSDSSSSSD 682
Query: 291 TRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTP 350
+ N+S + SSD++ S ES+ S + D DS +S + S +
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS----DSSNSNSSDSDSSNSSDSSDSS 738
Query: 351 NNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIM 410
N++ + +S S S + N+ S +S + +
Sbjct: 739 NSSDSSDSSDSSNSSDSSDSSDSS----------------NSSDSSDSSDSSDS------ 776
Query: 411 TGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSS 470
SDS + + S+ + + ++S + S SS SS SS S SS+SS
Sbjct: 777 -----------SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 471 SSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSS 506
SS+SS S SS S SSD +GS+ SS+ S
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861
Score = 73.9 bits (180), Expect = 4e-13
Identities = 98/450 (21%), Positives = 184/450 (40%), Gaps = 20/450 (4%)
Query: 73 EGPPPQNSDENRGGDS---SDDVSNGDSIIDWLNSVRQTGNTTRSGQ-RGNQSWRAVSRT 128
EGP ++ N+ G S SD S+G D+ + Q + S + GN + S
Sbjct: 424 EGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDN 483
Query: 129 NPNS-GDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSAR 187
N +S GD ++ + + + NGS + E++ S S N ++N N ++ + +
Sbjct: 484 NSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG 543
Query: 188 PSRSERNSTEALTEVPPTRGQRRARSRSPD-HRRTRARAERSRSPLHPMSEIPRRSHHSI 246
+S+ + +++ + + S S D + + + + S S S+ S+ S
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603
Query: 247 SSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAAS 306
SS + + +++ SS ++ + + + + S+ + S + ++S + SSD++ S
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSD-SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662
Query: 307 GESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRT 366
S+ S + D DS S S S +++ +S
Sbjct: 663 SNSSDSSDSSDS--SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 367 FSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDS 426
+ S+ + S+ ++ S +S + + + + S SDS
Sbjct: 721 SNSSDSDSSNSSDSS---------DSSNSSDSSDSSDSSNSSDSSDSSDSS--NSSDSSD 769
Query: 427 EPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESS 486
S S+ + ++S S SS SS SS+SS SS SS SS S S+SS +S
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829
Query: 487 ETSSDLFEGSNEGSSSSGSSGARREGRHRA 516
SSD S+ SS S G+ + +R+
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDSSNRS 859
Score = 69.7 bits (169), Expect = 8e-12
Identities = 102/506 (20%), Positives = 188/506 (37%), Gaps = 28/506 (5%)
Query: 3 NSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEE 62
++ S+ S D S + S D + ++ N+ D D++ + ++
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSS----NSSDSSDSSNSSDSSDSSDSSDGSDS 853
Query: 63 ELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSW 122
+ R +SD + DSSD + +S +S + + S N S
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS- 912
Query: 123 RAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSE 182
S + NS D S + N N+ ++ +++ S+ S+ + N+S + S+
Sbjct: 913 --DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970
Query: 183 STSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSP-LHPMSEIPRR 241
S S+ S S +S + + S S D + ++ S S S+
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030
Query: 242 SHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSS 301
S S SS + + +++ SS + + + S +S + ++S+ + SS
Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSESSDSS 1088
Query: 302 DTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERG 361
D++ S +S+ S + S +S + S + N++ + +S
Sbjct: 1089 DSSNSSDSSDSSDSSDS----------------SDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 362 GFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMY 421
S S + + S ++ S+++ + +
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 422 SDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSS 481
SDS S S+ + + ++S S SS S SS S+ SS SS SS SS S+SS
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250
Query: 482 GGESSETSSDLFEGSNEGSSSSGSSG 507
S SSD SN+ S S SG
Sbjct: 1251 DSSDSSDSSDSTSDSNDESDSQSKSG 1276
Score = 51.6 bits (122), Expect = 2e-06
Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 15/119 (12%)
Query: 422 SDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSS---------------SSSSS 466
++SDS G+ N + ++++S G+ S SS SS+SS SS S
Sbjct: 522 NNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD 581
Query: 467 SSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGS 525
SS S SS SS S SS +S SSD + S+ SS S + + + +S S
Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640
Score = 48.1 bits (113), Expect = 2e-05
Identities = 90/474 (18%), Positives = 175/474 (36%), Gaps = 16/474 (3%)
Query: 2 ENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTE 61
++SDS+D G S + RS N+ D D+N +S++
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSD---SSDSNESSNSSDSSD 896
Query: 62 EELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQS 121
+SD + DSS+ ++ D+ ++ + N++ S + S
Sbjct: 897 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN-----SNSSDSSNSSDSSDSSDSS 951
Query: 122 WRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRS 181
+ S + +S + S + N + ++ S NS + ++ S S ++ ++++ +
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 182 ESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERS-RSPLHPMSEIPR 240
S S+ S S +S + + S S D + + S S S+
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 241 RSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS 300
S S SS + E +++ SS + + S +S + N+S + S
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSNSSDSSDS 1129
Query: 301 SDTAASGE-STGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESE 359
SD++ S + S S + D DS S S S +++
Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189
Query: 360 RGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYF 419
+ S + S+ ++ S +S + ++ + + S
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS 1249
Query: 420 MYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSS 473
S S+ + S S+ N E ++S+S SG G+++GS S S S S S+ S+S
Sbjct: 1250 SDSSDSSDSSDSTSDSNDE-SDSQSK---SGNGNNNGSDSDSDSEGSDSNHSTS 1299
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 7/103 (6%)
Query: 423 DSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSG 482
D DS+ T +N + +G G +G + S S S SS S SS SS+ S SS
Sbjct: 512 DDDSDSTSDTNNSDS------NGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 483 GESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGS 525
S+ SSD S+ SS S SS + + + D S S
Sbjct: 566 SSDSD-SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607
Score = 30.8 bits (68), Expect = 3.9
Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 21/90 (23%)
Query: 436 NMERAESRSGRGGSGGGSSSGSSS--------------------SSSSSSSSSSSSSSSS 475
N+E +S G G S++GS S +SS S+ + ++S S
Sbjct: 422 NIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSES 481
Query: 476 SPSSSSGGESSETSSDLFEGSNEGSSSSGS 505
+SSS G++S S + + N GS S G+
Sbjct: 482 DNNSSSRGDASYNSDESKDNGN-GSDSKGA 510
>gi|14149702 ring finger protein 167 [Homo sapiens]
Length = 350
Score = 77.4 bits (189), Expect = 4e-14
Identities = 31/72 (43%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Query: 544 QPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSE 603
Q LTKEQ+ + + + D C++C+ EY +G+KLR LPC+H YH C+D WL++
Sbjct: 204 QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQ 263
Query: 604 -NSTCPICRRAV 614
TCPIC++ V
Sbjct: 264 TRKTCPICKQPV 275
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 73.9 bits (180), Expect = 4e-13
Identities = 95/335 (28%), Positives = 141/335 (42%), Gaps = 61/335 (18%)
Query: 210 RARSRSPDHRRTRAR--AERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRH 267
RARSR+P +++R +ER+ SP M + P +S + P+ + S ++R
Sbjct: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPV--PSAFSDQSRC 2461
Query: 268 HVTLRQQISGPELLSRGLFA----ASGTRNA-----SQGAGSSDTAASGESTGSGQRPPT 318
+ ++G + LS G A ++G N + G SD STG+ Q P+
Sbjct: 2462 LIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQ--PS 2519
Query: 319 IVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTY 378
+ LQ + R R S +S + S S + +++ + S G + S V+
Sbjct: 2520 ALAALQPAKER------RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
Query: 379 VSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNME 438
V+ R+P + + A + +R+ EPT +
Sbjct: 2574 VALKRVP-----------SPTPAPKEAVRE--------------GRPPEPTPA------- 2601
Query: 439 RAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEG--- 495
R R S SSS SSSSSSSSSSSSSSSSSSSS SSSS SS + S G
Sbjct: 2602 ---KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658
Query: 496 -SNEGSSSSGSSGARREGRHRAPV-TFDESGSLPF 528
S G RR R P+ + +S SL +
Sbjct: 2659 LPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
Score = 66.2 bits (160), Expect = 8e-11
Identities = 130/482 (26%), Positives = 176/482 (36%), Gaps = 53/482 (10%)
Query: 72 KEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGN-QSWRAVSRTNP 130
K P P + E +S + S+G + D +S + RS + R+ SRT
Sbjct: 442 KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPT 501
Query: 131 NSGDFRFSLEINVNRNNGSQNSENENEPSARRSS------GENVENNSQRQVENPRSEST 184
G R S R+ +Q P R S G + N+QR R S
Sbjct: 502 KRGHSR-SRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR-----RGRSR 555
Query: 185 SARPSRSERNST----EALTEVPPTRGQ--------RRARSRSPDHRRTRARAERSRSPL 232
SAR RS S + + P RG+ RR+RSR+P RR+R+R R
Sbjct: 556 SARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRS 615
Query: 233 HPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTR 292
+ RRS P+ + S R R + SR +R
Sbjct: 616 RSRTPARRRSR-------TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSR-------SR 661
Query: 293 NASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTP-- 350
++ S + S S R P + R R G R R S+ R RS S+TP
Sbjct: 662 TPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR-SLVRRGRSHSRTPQR 720
Query: 351 NNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTM-LRQI 409
SER RT R R+ + RI RR + LS S A + LR+
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR--SRSLSSPRSKAKSRLSLRRS 778
Query: 410 MTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSS 469
++G S S + P S S + +A+SR+ S SSS S + S S
Sbjct: 779 LSG---SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS-RSSSSPPPKQKSKTPSRQS 834
Query: 470 SSSSSSSPSSSSG---GESSETSSDLFEGS-NEGSSSSGSSGARREGRHRAPVTFDESGS 525
SSSS P SG + S TS E S S S E + R P SGS
Sbjct: 835 HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894
Query: 526 LP 527
P
Sbjct: 895 SP 896
Score = 53.5 bits (127), Expect = 6e-07
Identities = 77/297 (25%), Positives = 113/297 (38%), Gaps = 57/297 (19%)
Query: 111 TTRSGQRGNQSWRAVSRTNPNSGDFRFSLEIN----VNRNNGSQNSENENE----PSARR 162
T R G R + + SRT P R S E+ ++R + S +S E P RR
Sbjct: 1667 TARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR 1726
Query: 163 SSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTR 222
S + +++ + R S S+ R++ S + P RG +R+RSRS
Sbjct: 1727 SPSVSSPEPAEKSRSSRRRRSASS--PRTKTTSRRGRSPSPKPRGLQRSRSRS------- 1777
Query: 223 ARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLS 282
R E++R+ RR S SSQ+ + SR+R VT R++
Sbjct: 1778 -RREKTRT--------TRRRDRSGSSQS-----TSRRRQRSRSRSRVTRRRR-------- 1815
Query: 283 RGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVR-----------RVRPG 331
SG + S S +S G + PPT + R R P
Sbjct: 1816 ----GGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPA 1871
Query: 332 EYRQ---RDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIP 385
+R+ R + SR RSRS+T + R R SRS + V S R P
Sbjct: 1872 THRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTP 1928
Score = 47.0 bits (110), Expect = 5e-05
Identities = 106/424 (25%), Positives = 154/424 (36%), Gaps = 87/424 (20%)
Query: 102 LNSVRQTGNTTRSGQRGNQSWRAVSRT----NPNSGDFRFSLEINVNRNNGSQN-SENEN 156
LN+ T RSG + + V+RT SG S E++V + Q SE+++
Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS---SQELDVKPSASPQERSESDS 1561
Query: 157 EPSARRSSGENVENNSQRQVENPRSESTSA-RPSRSERNSTEALTEVPPTRGQRRARSRS 215
P ++ + + S R +P +S S P RS S+ + + P R RA+S S
Sbjct: 1562 SPDSKAKTRTPLRQRS-RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP--RAAPRAQSGS 1618
Query: 216 PDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQI 275
+A A R+ +PRRS SS+ P EGSS T
Sbjct: 1619 DSSPEPKAPAPRA---------LPRRSRSGSSSKG-RGP---SPEGSSSTE--------- 1656
Query: 276 SGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQ 335
S PE + A G+R++ + S T S+ S R+ R R+
Sbjct: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE--------LTRKARLS--RR 1706
Query: 336 RDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLS 395
S +S +RS+TP S SRS R RR ++ +
Sbjct: 1707 SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR-------------RRSASSPRT 1753
Query: 396 ETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSS 455
+TTS ++ S R ++R+ SRS R +
Sbjct: 1754 KTTSRRGRSP-------------------------SPKPRGLQRSRSRSRREKTRTTRRR 1788
Query: 456 GSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHR 515
S SS S+S S S S + G S S S SS +S RR GR R
Sbjct: 1789 DRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR-----SPARQESSRTSSRRRRGRSR 1843
Query: 516 APVT 519
P T
Sbjct: 1844 TPPT 1847
Score = 45.4 bits (106), Expect = 2e-04
Identities = 84/386 (21%), Positives = 135/386 (34%), Gaps = 34/386 (8%)
Query: 141 INVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPR---------SESTSARPSRS 191
++ R+ + E +++P A + +++ + + PR S S PS
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 192 ERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTF 251
+STE+ E PP R SRS +T++R R E+ R++ S S++
Sbjct: 1651 GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA 1710
Query: 252 EHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTG 311
+ E SRT +S PE + +S R ++ + T+ G S
Sbjct: 1711 S----SSPETRSRTPPRHRRSPSVSSPEPAEKS--RSSRRRRSASSPRTKTTSRRGRSPS 1764
Query: 312 SGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSE 371
R LQ R R R+ + +R R RS + +T + +R R +R
Sbjct: 1765 PKPR------GLQRSRSRS---RREKTRTTRRRDRSGSSQST-SRRRQRSRSRSRVTRRR 1814
Query: 372 RAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGS 431
R G + R P R+ + S +T S + S S + +
Sbjct: 1815 RGGSGYH---SRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPA 1871
Query: 432 VSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSD 491
R+ R S R S S S +S + S S +SP S S
Sbjct: 1872 THRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPP-- 1929
Query: 492 LFEGSNEGSSSSGSSGARREGRHRAP 517
S S + RR R R P
Sbjct: 1930 ----VTRRRSRSRTPTTRRRSRSRTP 1951
Score = 45.1 bits (105), Expect = 2e-04
Identities = 81/366 (22%), Positives = 134/366 (36%), Gaps = 55/366 (15%)
Query: 157 EPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSP 216
E S+ RS + +++ RSES+S R R + + + ++ +R+ RS +P
Sbjct: 176 ESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK-KRKHRSPTP 234
Query: 217 DHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEG-SSRTRHHVTLRQQI 275
+R +R RS + RR+H S S+ + + + S+ + H T
Sbjct: 235 KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTT----- 289
Query: 276 SGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQ 335
L R ASG R G D S T S QRP + + + P E +
Sbjct: 290 ---ALAGRSPSPASGRR------GEGDAPFSEPGTTSTQRPSSPETATK-QPSSPYEDKD 339
Query: 336 RDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLS 395
+D S +P + T T +ER G + + T LS
Sbjct: 340 KDKKEKSATRPSPSPERSSTGPEPPA---PTPLLAERHGGSP---------QPLATTPLS 387
Query: 396 ETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSS 455
+ + S++ PT +R+ ++ + + S S
Sbjct: 388 QEP---------------------VNPPSEASPT---RDRSPPKSPEKLPQSSSSESSPP 423
Query: 456 GSSSSSSSSSSSSSSSSSSSSPSSSSGGE--SSETSSDLFEGSNEGSSSSGSSGARREGR 513
+ S +SSS S +P+ S E SS TS + G + S + +RR GR
Sbjct: 424 SPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGR 483
Query: 514 HRAPVT 519
R+P T
Sbjct: 484 SRSPAT 489
Score = 41.6 bits (96), Expect = 0.002
Identities = 83/382 (21%), Positives = 123/382 (32%), Gaps = 39/382 (10%)
Query: 150 QNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQR 209
++ E N P S G +E + + + S+ E P+ +
Sbjct: 1313 EHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMK 1372
Query: 210 RARSRSPDHRRTRARAERSRSPLHP--MSEIPRRSHHSISSQTFEHPLVNETEGSSRTRH 267
+RS H S S L P + + S+ SISS + V T R+
Sbjct: 1373 EQSTRSSGH---------SSSELSPDAVEKAGMSSNQSISSPVLD--AVPRTPSRERSSS 1421
Query: 268 HVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQV-- 325
+ + P SR + S S + SG S G P T
Sbjct: 1422 ASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECD 1481
Query: 326 RRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIP 385
P Q SR+ S + N +T + ER G + + A R P
Sbjct: 1482 SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVA---------RTP 1532
Query: 386 IRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSG 445
+ + +G S+ V ++ S+SDS P R R SRSG
Sbjct: 1533 LGQRSRSGSSQELDVKPSASPQE------------RSESDSSPDSKAKTRTPLRQRSRSG 1580
Query: 446 RGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGS 505
S S S S SS ++P + SG +SS + S SGS
Sbjct: 1581 SSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGS 1640
Query: 506 SGARREGRHRAPVTFDESGSLP 527
S +GR +P + S P
Sbjct: 1641 SS---KGRGPSPEGSSSTESSP 1659
Score = 40.8 bits (94), Expect = 0.004
Identities = 63/220 (28%), Positives = 88/220 (40%), Gaps = 21/220 (9%)
Query: 298 AGSSDTAASGES--TGSGQRPPTIVLDLQVRRVRPGEYRQ---RDSIASRTRSRSQTPNN 352
AGS AA + T + P +L RV Y + R S R+RS+TP +
Sbjct: 2353 AGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS 2412
Query: 353 TVTYESERGGFRRTFSRSERAGVRTYVSTI-------RIPIRRILNTG----LSETTSVA 401
+ R R S S R G S + R P+ + +++TT VA
Sbjct: 2413 APS--QSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVA 2470
Query: 402 IQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSS 461
L S ++ S P V + ++ + +G ++ +
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKER 2530
Query: 462 SSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSS 501
SSSSSSSSSSSSSS SSSS SS SS +EGSS
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSS---SSDSEGSS 2567
Score = 39.7 bits (91), Expect = 0.008
Identities = 65/245 (26%), Positives = 93/245 (37%), Gaps = 35/245 (14%)
Query: 123 RAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSE 182
R+ SRT+P S R +V R + S + P +RR S ++R RS
Sbjct: 1887 RSRSRTSPVSRR-RSRSRTSVTR----RRSRSRASPVSRRRSRSRTPPVTRR-----RSR 1936
Query: 183 STSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARA-------ERSRSPLHPM 235
S + R R+ T +T +RR+RSR+P R R+R+ RSRS P
Sbjct: 1937 SRTPTTRRRSRSRTPPVT-------RRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSP- 1988
Query: 236 SEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNAS 295
+ RR S +S + T +R R I L +R+ S
Sbjct: 1989 --VTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRS 2046
Query: 296 QGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVT 355
A + + T G+R T R P R+ S +S RSRS TP T
Sbjct: 2047 PLAIRRRSRSRTPRTARGKRSLT--------RSPPAIRRRSASGSSSDRSRSATPPATRN 2098
Query: 356 YESER 360
+ R
Sbjct: 2099 HSGSR 2103
Score = 36.6 bits (83), Expect = 0.071
Identities = 44/178 (24%), Positives = 67/178 (37%), Gaps = 28/178 (15%)
Query: 69 QQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRT 128
+ ++EG PP+ + R SS S+ S +S + +++ S + S + S +
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 129 NPNSGDFRFSLEINVNRNNGSQ-----NSENENEPSARRSSGENVENNS---QRQVENPR 180
+P+ G Q S + P RRS +S R +
Sbjct: 2648 SPSPA------------KPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSP 2695
Query: 181 SESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTR-------ARAERSRSP 231
E P S R+ + +E RGQ R SRSP H+R R R SRSP
Sbjct: 2696 VERRRPSPQPSPRDQQSSSSERGSRRGQ-RGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 36.6 bits (83), Expect = 0.071
Identities = 31/132 (23%), Positives = 53/132 (40%), Gaps = 3/132 (2%)
Query: 145 RNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPP 204
R++ S +S + + S+ SS + ++S + S S+S+ PS ++ P
Sbjct: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP 2665
Query: 205 TR---GQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEG 261
+ G+RR+RS R S SP+ P+ S S + E G
Sbjct: 2666 KKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG 2725
Query: 262 SSRTRHHVTLRQ 273
SR+ H R+
Sbjct: 2726 DSRSPSHKRRRE 2737
Score = 30.8 bits (68), Expect = 3.9
Identities = 24/73 (32%), Positives = 32/73 (43%)
Query: 457 SSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRA 516
S+ SS SSS S + + SS+ SS + + SSS SS ++G R
Sbjct: 1375 STRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRT 1434
Query: 517 PVTFDESGSLPFL 529
P SGS P L
Sbjct: 1435 PSRRSRSGSSPGL 1447
Score = 29.6 bits (65), Expect = 8.7
Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 428 PTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSE 487
P +++ +R SRS + S+S+ S+SSS +S S S S+ + + +
Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293
Query: 488 TSSDLFEG-SNEGSSSSGSSGARREGRHRAPVTFDESGSLPF 528
S G EG + G R +P T + S P+
Sbjct: 294 RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPY 335
>gi|37577185 ring finger protein 38 isoform 2 [Homo sapiens]
Length = 432
Score = 73.6 bits (179), Expect = 5e-13
Identities = 32/71 (45%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
Query: 544 QPRGLTKEQIDNLAMRSFGENDALKT---CSVCITEYTEGNKLRKLPCSHEYHVHCIDRW 600
+PRGLTK I+ L F N+ C VC+ ++ LR LPC+HE+H C+D+W
Sbjct: 351 KPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKW 410
Query: 601 LSENSTCPICR 611
L N TCPICR
Sbjct: 411 LKANRTCPICR 421
>gi|37577181 ring finger protein 38 isoform 2 [Homo sapiens]
Length = 432
Score = 73.6 bits (179), Expect = 5e-13
Identities = 32/71 (45%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
Query: 544 QPRGLTKEQIDNLAMRSFGENDALKT---CSVCITEYTEGNKLRKLPCSHEYHVHCIDRW 600
+PRGLTK I+ L F N+ C VC+ ++ LR LPC+HE+H C+D+W
Sbjct: 351 KPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKW 410
Query: 601 LSENSTCPICR 611
L N TCPICR
Sbjct: 411 LKANRTCPICR 421
>gi|37577179 ring finger protein 38 isoform 3 [Homo sapiens]
Length = 465
Score = 73.6 bits (179), Expect = 5e-13
Identities = 32/71 (45%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
Query: 544 QPRGLTKEQIDNLAMRSFGENDALKT---CSVCITEYTEGNKLRKLPCSHEYHVHCIDRW 600
+PRGLTK I+ L F N+ C VC+ ++ LR LPC+HE+H C+D+W
Sbjct: 384 KPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKW 443
Query: 601 LSENSTCPICR 611
L N TCPICR
Sbjct: 444 LKANRTCPICR 454
>gi|37577177 ring finger protein 38 isoform 2 [Homo sapiens]
Length = 432
Score = 73.6 bits (179), Expect = 5e-13
Identities = 32/71 (45%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
Query: 544 QPRGLTKEQIDNLAMRSFGENDALKT---CSVCITEYTEGNKLRKLPCSHEYHVHCIDRW 600
+PRGLTK I+ L F N+ C VC+ ++ LR LPC+HE+H C+D+W
Sbjct: 351 KPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKW 410
Query: 601 LSENSTCPICR 611
L N TCPICR
Sbjct: 411 LKANRTCPICR 421
>gi|37577175 ring finger protein 38 isoform 1 [Homo sapiens]
Length = 515
Score = 73.6 bits (179), Expect = 5e-13
Identities = 32/71 (45%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
Query: 544 QPRGLTKEQIDNLAMRSFGENDALKT---CSVCITEYTEGNKLRKLPCSHEYHVHCIDRW 600
+PRGLTK I+ L F N+ C VC+ ++ LR LPC+HE+H C+D+W
Sbjct: 434 KPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKW 493
Query: 601 LSENSTCPICR 611
L N TCPICR
Sbjct: 494 LKANRTCPICR 504
>gi|7662486 ring finger protein 44 [Homo sapiens]
Length = 432
Score = 72.8 bits (177), Expect = 9e-13
Identities = 32/73 (43%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 542 DDQPRGLTKEQIDNLAMRSFGENDALKT---CSVCITEYTEGNKLRKLPCSHEYHVHCID 598
D +PRGLTK I+ L F + C VC +++ LR LPC+HE+H C+D
Sbjct: 349 DAKPRGLTKADIEQLPSYRFNPDSHQSEQTLCVVCFSDFEARQLLRVLPCNHEFHTKCVD 408
Query: 599 RWLSENSTCPICR 611
+WL N TCPICR
Sbjct: 409 KWLKANRTCPICR 421
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 72.0 bits (175), Expect = 2e-12
Identities = 45/84 (53%), Positives = 50/84 (59%)
Query: 423 DSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSG 482
D + + RN A SR+ S SSS SSSSSSSSSSSSSSSSSSSS SSSS
Sbjct: 2588 DKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 483 GESSETSSDLFEGSNEGSSSSGSS 506
SS +SS S+ SSSS SS
Sbjct: 2648 SSSSSSSSSSSSSSSSSSSSSSSS 2671
Score = 70.5 bits (171), Expect = 4e-12
Identities = 52/122 (42%), Positives = 61/122 (50%), Gaps = 16/122 (13%)
Query: 422 SDSDSEPTGSVSNRNMERAESRSGRGGSGGG----------------SSSGSSSSSSSSS 465
S S S + S S E ++G GG G G SSS SSSSSSSSS
Sbjct: 2568 SSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSS 2627
Query: 466 SSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGS 525
SSSSSSSSSSS SSSS SS +SS S+ SSSS SS + + + DE+
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687
Query: 526 LP 527
P
Sbjct: 2688 AP 2689
Score = 62.4 bits (150), Expect = 1e-09
Identities = 40/86 (46%), Positives = 52/86 (60%)
Query: 422 SDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSS 481
S + S + S S+ + + S S S SSS SSSSSSSSSSSSSSSSSSSS SSSS
Sbjct: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
Query: 482 GGESSETSSDLFEGSNEGSSSSGSSG 507
SS T D S++ ++ + ++G
Sbjct: 2667 SSSSSTTDEDSSCSSDDEAAPAPTAG 2692
Score = 60.8 bits (146), Expect = 4e-09
Identities = 40/87 (45%), Positives = 49/87 (56%)
Query: 426 SEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGES 485
S S ++ + + S S S SSS SSSSSSSSSSSSSSSSSSSS SSSS S
Sbjct: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665
Query: 486 SETSSDLFEGSNEGSSSSGSSGARREG 512
S +SS + + SS ++ A G
Sbjct: 2666 SSSSSSTTDEDSSCSSDDEAAPAPTAG 2692
Score = 59.3 bits (142), Expect = 1e-08
Identities = 35/87 (40%), Positives = 49/87 (56%)
Query: 422 SDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSS 481
S S S + S S+ + E + G GG + G + S++SS ++S +SSSSSS SSSS
Sbjct: 2565 SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSS 2624
Query: 482 GGESSETSSDLFEGSNEGSSSSGSSGA 508
SS +SS S+ SSSS SS +
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSS 2651
Score = 55.8 bits (133), Expect = 1e-07
Identities = 38/124 (30%), Positives = 56/124 (45%)
Query: 422 SDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSS 481
S S + S S+ E G GG +G + S++SS ++S +SSSSS SSSS
Sbjct: 2564 SSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSS 2623
Query: 482 GGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNEDD 541
SS +SS S+ SSSS SS + + + S S + + + DD
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDD 2683
Query: 542 DDQP 545
+ P
Sbjct: 2684 EAAP 2687
Score = 53.5 bits (127), Expect = 6e-07
Identities = 34/94 (36%), Positives = 48/94 (51%)
Query: 422 SDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSS 481
S S S + S S+ + + S S S SSS SSSSSSSSSSSSSSSSSSS+ S
Sbjct: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDS 2677
Query: 482 GGESSETSSDLFEGSNEGSSSSGSSGARREGRHR 515
S + ++ ++ + ++ G+ R
Sbjct: 2678 SCSSDDEAAPAPTAGPSAQAALPTKATKQAGKAR 2711
Score = 50.8 bits (120), Expect = 4e-06
Identities = 36/109 (33%), Positives = 50/109 (45%), Gaps = 21/109 (19%)
Query: 421 YSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSS------------- 467
+ DS + + + + AE S GSSS SSSSSSS S +
Sbjct: 2535 FEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGG 2594
Query: 468 --------SSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGA 508
S++SS ++SP+SSS SS +SS S+ SSSS SS +
Sbjct: 2595 CGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Score = 45.8 bits (107), Expect = 1e-04
Identities = 32/86 (37%), Positives = 43/86 (50%)
Query: 423 DSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSG 482
D EP ++ + +S G+ SSSSSSS SSSSSSSSSSS S + G
Sbjct: 2524 DLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEG 2583
Query: 483 GESSETSSDLFEGSNEGSSSSGSSGA 508
E + + D G+ + S+ SS A
Sbjct: 2584 EEEGDKNGDGGCGTGGRNCSAASSRA 2609
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/67 (37%), Positives = 35/67 (52%)
Query: 459 SSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPV 518
+ S SSSSSSS SSSSS SSSS G +E + + + G + G + + R +P
Sbjct: 2554 AEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPA 2613
Query: 519 TFDESGS 525
+ S S
Sbjct: 2614 SSSSSSS 2620
Score = 30.0 bits (66), Expect = 6.7
Identities = 15/38 (39%), Positives = 21/38 (55%)
Query: 480 SSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAP 517
S+ S +TS D EG + G++ S GA+ GR R P
Sbjct: 2299 SAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKP 2336
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 65.5 bits (158), Expect = 1e-10
Identities = 105/451 (23%), Positives = 169/451 (37%), Gaps = 50/451 (11%)
Query: 102 LNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSEN-----EN 156
L + + T+ S G+ + + T NSG S ++ +GS + N N
Sbjct: 18 LEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTN 77
Query: 157 EPSARRSSGENVENNSQRQVENP------RSESTSARPSRSERNSTEALTEVPPTRGQRR 210
SSG + NS+ + SES++ S ++E+ T P+ G
Sbjct: 78 SEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESST---PSSGAST 134
Query: 211 ARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVT 270
A + + A + SE ++ S+ + +E S+ + T
Sbjct: 135 ATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRAST 194
Query: 271 LRQQISGPELLSRGLFAASGTRNASQGAGS-----SDTAASGESTGSGQRPPTIVLDLQV 325
S S +R S GAG+ S T +SG ST + T
Sbjct: 195 ATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESST------- 247
Query: 326 RRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSER--AGVRTYV---- 379
G +S +S T S + T N+ + G T S S +G T
Sbjct: 248 --PSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSES 305
Query: 380 STIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMER 439
ST N+ S T+S A + T S S+S + +G+ + N
Sbjct: 306 STTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGS 365
Query: 440 AESRSGRGGS--------GGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSG------GES 485
+ + SG + G+S+ ++S SS++SS +S++++S S + SSG ES
Sbjct: 366 STTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSES 425
Query: 486 SETSSDLFEGSNEGSS--SSGSSGARREGRH 514
S TSS +N GSS S+GS A G H
Sbjct: 426 STTSSGANTATNSGSSVTSAGSGTAALTGMH 456
Score = 47.4 bits (111), Expect = 4e-05
Identities = 85/404 (21%), Positives = 151/404 (37%), Gaps = 40/404 (9%)
Query: 92 VSNGDSIIDWLNSVRQT----GNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNN 147
VS+G SI NS T +T + + S A + TN +S N ++
Sbjct: 98 VSSGISIAT--NSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDS 155
Query: 148 GSQNSENE---NEPSARRSSGENVENNSQRQVENPR-SESTSARPSRSERNSTEALTEVP 203
+ +SE N S+ SSG + NS+ + R S +T++ S + ++ A
Sbjct: 156 STTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSES 215
Query: 204 PTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSS 263
T + + + T + A + + SE S + ++ E + G++
Sbjct: 216 RTTSNGAGTATNSESSTTSSGASTATN-----SESSTPSSGAGTATNSESSTTSSGAGTA 270
Query: 264 RTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDL 323
T+ IS S +SG A+ S T +SG +T + T
Sbjct: 271 TNSESSTVSSGIS-TVTNSESSTPSSGANTATNS--ESSTTSSGANTATNSDSST----- 322
Query: 324 QVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIR 383
G +S +S T S + T N+ + + G T S S T +T
Sbjct: 323 ----TSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTAT-- 376
Query: 384 IPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESR 443
N+ S +S A + T S S+S + +G+ + N E + +
Sbjct: 377 -------NSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTS 429
Query: 444 SGRGGSGGGSSS----GSSSSSSSSSSSSSSSSSSSSPSSSSGG 483
SG + SS GS +++ + ++S S+S++ + GG
Sbjct: 430 SGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGG 473
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 65.1 bits (157), Expect = 2e-10
Identities = 114/455 (25%), Positives = 169/455 (37%), Gaps = 36/455 (7%)
Query: 73 EGPPPQNSDENRGGDSSDDVSNGDSIIDWLNS--VRQTGNTTRSGQRGNQSWRAVSRTNP 130
+ P P G S S S W +S ++G++ SG +S R+
Sbjct: 1475 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRES-----RSGQ 1529
Query: 131 NSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSR 190
+SG + + +G S + S + + +++S Q + S+S+
Sbjct: 1530 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 1589
Query: 191 SERNSTEALTEVPPTRGQRRARSR-SPDHRRTRARAERSRSPLHPMSEIPRRS----HHS 245
S + P GQR + SR SP + R + + RS S S + S H S
Sbjct: 1590 SGSGQS-------PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 1642
Query: 246 ISSQTFEHPLVNETEG-SSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTA 304
S Q+ + G SS H + Q S E G + S +R G+GS ++
Sbjct: 1643 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHGSSSRSSSRYGQHGSGSRQSS 1700
Query: 305 ASG-ESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGF 363
G + +GSGQ P R R G S + S S ++ YES R G
Sbjct: 1701 GHGRQGSGSGQSPS---------RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYES-RSGH 1750
Query: 364 RRTFSRSER-AGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYS 422
F + E +G + S + G +TS T Q + G+ S
Sbjct: 1751 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF-DQEGSSTGQSSSHGQH 1809
Query: 423 DSDSEPTGSVSNRNMERAESRS-GRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSS 481
S S + S + +S S GR GSG G SS S S SSSS S SS
Sbjct: 1810 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1869
Query: 482 GGESSETSSDLFEGSNEGSSSSGSSGARREGRHRA 516
G E+SS G + S SG S + + R+
Sbjct: 1870 GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS 1904
Score = 62.0 bits (149), Expect = 2e-09
Identities = 93/414 (22%), Positives = 153/414 (36%), Gaps = 71/414 (17%)
Query: 108 TGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGEN 167
+G+++ GQ G+ S + SR + SG + S +G + +++ + SS +
Sbjct: 316 SGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQG 375
Query: 168 VENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARS-RSPDHRRTRARAE 226
++ Q + +S+R S S E+ + RGQ + S +SP H + + +
Sbjct: 376 QHGSTSGQASSSGQHGSSSRQS-SSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSG 434
Query: 227 RSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLF 286
+S S + R S P V+ + SS HH + + SG
Sbjct: 435 QSPSSGQHGTGFGRSSSSG--------PYVSGSGYSSGFGHHESSSEHSSG--------- 477
Query: 287 AASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSR 346
G+GS G S+G GQ + R +SR +
Sbjct: 478 ------YTQHGSGS------GHSSGHGQ------------------HGSRSGQSSRGERQ 507
Query: 347 SQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTML 406
+ ++ +Y G R++ S +G S + S
Sbjct: 508 GSSAGSSSSYGQHGSGSRQSLGHSRHGS----------------GSGQSPSPSRGRHESG 551
Query: 407 RQIMTGFGELSYFMYSDSDSEP--TGSVSNRNMERAESRSGRGGSGG--GSSSGSSSSSS 462
+ + +G Y S P +GS + + ESRSG+ G GSSSG SS+
Sbjct: 552 SRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHG 611
Query: 463 SSSSSSSSSSSSSSPSSSSGGESS--ETSSDLFEGSNEGSSSSGSSGARREGRH 514
S+S SSS ++SG SS + S + S G SGS + GRH
Sbjct: 612 QHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRH 665
Score = 59.7 bits (143), Expect = 8e-09
Identities = 110/455 (24%), Positives = 165/455 (36%), Gaps = 36/455 (7%)
Query: 73 EGPPPQNSDENRGGDSSDDVSNGDSIIDWLNS--VRQTGNTTRSGQRGNQSWRAVSRTNP 130
+ P P G S S W +S ++G+ SG +S R+
Sbjct: 1005 QSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRES-----RSGQ 1059
Query: 131 NSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSR 190
+SG + + +G S + S + + +++S Q + S+S+
Sbjct: 1060 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 1119
Query: 191 SERNSTEALTEVPPTRGQRRARSR-SPDHRRTRARAERSRSPLHPMSEIPRRS----HHS 245
S + P GQR + SR SP + R + + RS S S + S H S
Sbjct: 1120 SGSGQS-------PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 1172
Query: 246 ISSQTFEHPLVNETEG-SSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTA 304
S Q+ + G SS H + Q S E G + S + G+GS ++
Sbjct: 1173 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHGSSSGSSSHYGQHGSGSRQSS 1230
Query: 305 ASG-ESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGF 363
G + +GSG P R R G S + S S ++ YES R G
Sbjct: 1231 GHGRQGSGSGHSPS---------RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYES-RSGH 1280
Query: 364 RRTFSRSER-AGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYS 422
F + E +G + S + G +TS T Q + G+ S + +
Sbjct: 1281 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF-DQEGSSTGQSSSYGHR 1339
Query: 423 DSDSEPTGSVSNRNMERAESRS-GRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSS 481
S S + +S S GR GSG G SS S S SSSS S SS
Sbjct: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1399
Query: 482 GGESSETSSDLFEGSNEGSSSSGSSGARREGRHRA 516
G E+SS G + S SG S + + R+
Sbjct: 1400 GFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRS 1434
Score = 59.3 bits (142), Expect = 1e-08
Identities = 111/455 (24%), Positives = 165/455 (36%), Gaps = 36/455 (7%)
Query: 73 EGPPPQNSDENRGGDSSDDVSNGDSIIDWLNS--VRQTGNTTRSGQRGNQSWRAVSRTNP 130
+ P P G S S W +S ++G+ SG +S R+
Sbjct: 1945 QSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRES-----RSGQ 1999
Query: 131 NSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSR 190
+SG + + +G S + S + + +++S Q + S+S+
Sbjct: 2000 SSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2059
Query: 191 SERNSTEALTEVPPTRGQRRARSR-SPDHRRTRARAERSRSPLHPMSEIPRRS----HHS 245
S + P GQR + SR SP + R + + RS S + S H S
Sbjct: 2060 SGSGQS-------PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHES 2112
Query: 246 ISSQTFEHPLVNETEG-SSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTA 304
S Q+ + G SS H + Q S E G + S +R G+GS ++
Sbjct: 2113 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHGSSSGSSSRYGQHGSGSRQSS 2170
Query: 305 ASG-ESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGF 363
G + +GSG P R R G S + S S ++ YES R G
Sbjct: 2171 GHGRQGSGSGHSPS---------RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYES-RSGH 2220
Query: 364 RRTFSRSER-AGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYS 422
F + E +G + S + G +TS T Q + G+ S
Sbjct: 2221 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF-DQEGSSTGQSSSHGQH 2279
Query: 423 DSDSEPTGSVSNRNMERAESRS-GRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSS 481
S S + S + +S S GR GSG G SS S S SSSS S SS
Sbjct: 2280 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 2339
Query: 482 GGESSETSSDLFEGSNEGSSSSGSSGARREGRHRA 516
G E+SS G + S SG S + + R+
Sbjct: 2340 GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS 2374
Score = 56.6 bits (135), Expect = 7e-08
Identities = 113/436 (25%), Positives = 160/436 (36%), Gaps = 49/436 (11%)
Query: 108 TGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGEN 167
+G + GQ + S + S+ SG FS + +G +S +++ S+ +SS
Sbjct: 811 SGQASGFGQHESGSGQGYSQHGSASG--HFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
Query: 168 VENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARS-RSPDHRRTRARAE 226
+ ES S S R+ + + P GQR + S +SP + R + +
Sbjct: 869 ------------QHESASHHASGRGRHGSGSGQS--PGHGQRGSGSGQSPSYGRHGSGSG 914
Query: 227 RSRSPLHPMSEIPRRS---HHSISSQTFEHPLVNETEG-SSRTRHHVTLRQQISGPELLS 282
RS S S + S H S S Q+ + G SS H + Q S E
Sbjct: 915 RSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE--Q 972
Query: 283 RGLFAASGTRNASQGAGSSDTAASGE-STGSGQRPPTIVLDLQVRRVRPGEYRQRDSIAS 341
G + S + G+GS + G+ +GSGQ P R R G + S
Sbjct: 973 HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP-------SRGRHGSGSGQSSSYG 1025
Query: 342 RTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVA 401
RS S ++ YES G R R+G + + ++G S T
Sbjct: 1026 PYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG------QHGSSSGHSSTHGQH 1079
Query: 402 IQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSS 461
T + G S S +GS + R S SG+ G SGS S
Sbjct: 1080 GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP 1139
Query: 462 SSSSSSSSSSSSSSSPSSSSG-GESS----------ETSSDLFEGSNEGSSSS-GSSGAR 509
S S S SSSS SG GESS ++SS GS G SS G G+R
Sbjct: 1140 SYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1199
Query: 510 REGRHRAPVTFDESGS 525
R SGS
Sbjct: 1200 SGQSSRGERHGSSSGS 1215
Score = 56.2 bits (134), Expect = 9e-08
Identities = 114/508 (22%), Positives = 194/508 (38%), Gaps = 73/508 (14%)
Query: 18 QRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPP 77
Q ++ + R+E+ + + + E+ R N+ G+ TE + RRL ++
Sbjct: 112 QEETEKEENKRQESSFSHSSWSAGENDSYSR--NVRGSLKPGTES-ISRRLSFQRDFSGQ 168
Query: 78 QNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRF 137
NS G SS N DS ++ GQ G+ S ++ + SG +
Sbjct: 169 HNSYS--GQSSSYGEQNSDS-----------HQSSGRGQCGSGSGQSPNYGQHGSGSGQS 215
Query: 138 SLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVEN-PRSESTSARPSRSERNST 196
S +G + ++++ S+ +SSG + + + S S + SR ER+ +
Sbjct: 216 SSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRS 275
Query: 197 EALTEVPPTRGQRRARSR-SPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPL 255
+ + + GQ + SR S H R + + +S S + H S S + H
Sbjct: 276 SSGSS--SSYGQHGSGSRQSLGHGRQGSGSRQSPSHVR---------HGSGSGHSSSHGQ 324
Query: 256 VNETEGSSRTR-HHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDT-----AASGES 309
S +R H+ + Q SG G +SG G+G S + + SG++
Sbjct: 325 HGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQA 384
Query: 310 TGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFS- 368
+ SGQ + + Y Q +S + + R Q +++ + +S G R + S
Sbjct: 385 SSSGQHGSS--------SRQSSSYGQHESASRHSSGRGQ--HSSGSGQSPGHGQRGSGSG 434
Query: 369 RSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEP 428
+S +G TG ++S ++G G S F + +S SE
Sbjct: 435 QSPSSGQH--------------GTGFGRSSSSG------PYVSGSGYSSGFGHHESSSEH 474
Query: 429 TGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSET 488
+ + SG G S G GS S SS SS+ SSS G S ++
Sbjct: 475 SSGYTQHG-------SGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQS 527
Query: 489 SSDLFEGSNEGSSSSGSSGARREGRHRA 516
GS G S S S G G ++
Sbjct: 528 LGHSRHGSGSGQSPSPSRGRHESGSRQS 555
Score = 55.1 bits (131), Expect = 2e-07
Identities = 111/450 (24%), Positives = 163/450 (36%), Gaps = 55/450 (12%)
Query: 73 EGPPPQNSDENRGGDSSDDVSNGDSIIDWLNS--VRQTGNTTRSGQRGNQSWRAVSRTNP 130
+ P P G S S S W +S ++G+ SG +S R+
Sbjct: 2415 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRES-----RSGQ 2469
Query: 131 NSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSR 190
+SG + + +G S + S + + +++S Q + S+S+
Sbjct: 2470 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2529
Query: 191 SERNSTEALTEVPPTRGQRRARSR-SPDHRRTRARAERSRSPLHPMSEIPRRS----HHS 245
S + P GQR + SR SP + R + + RS S S + S H S
Sbjct: 2530 SGSGQS-------PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 2582
Query: 246 ISSQTFEHPLVNETEG-SSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTA 304
S Q+ + G SS H + Q S E G + S + G+GS ++
Sbjct: 2583 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE--RHGSSSGSSSHYGQHGSGSRQSS 2640
Query: 305 ASG-ESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGF 363
G + +GSGQ P R R G S + S S ++ YES R G
Sbjct: 2641 GHGRQGSGSGQSPS---------RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYES-RLGH 2690
Query: 364 RRTFSRSER-AGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYS 422
F + E +G + S + G +TS G+ S F
Sbjct: 2691 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS--------------GQSSTFDQE 2736
Query: 423 DSDSEPTGSVSNRNMERAESRS-GRGGSGGGSS-----SGSSSSSSSSSSSSSSSSSSSS 476
S + + S +R ++S GR G+G G S GS S SSS S S SS
Sbjct: 2737 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSS 2796
Query: 477 PSSSSG-GESSETSSDLFEGSNEGSSSSGS 505
S G G + S GSN SSGS
Sbjct: 2797 GYSQHGSGSGQDGYSYCKGGSNHDGGSSGS 2826
Score = 52.0 bits (123), Expect = 2e-06
Identities = 104/420 (24%), Positives = 157/420 (37%), Gaps = 52/420 (12%)
Query: 108 TGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGEN 167
+G + G+ G+ S + S SG S +G + +E S+ +SSG
Sbjct: 2296 SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYT 2355
Query: 168 VENN-SQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSR-SPDHRRTRARA 225
+ S + S S + SR ER+ + + + + GQ + SR S H + + +
Sbjct: 2356 QHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS--SSYGQHGSGSRQSLGHGQHGSGS 2413
Query: 226 ERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGL 285
+S SP R H S S Q+ + G S +R GP G
Sbjct: 2414 GQSPSP-------SRGRHGSGSGQSSSYSPYGSGSGWSSSR----------GPYESGSGH 2456
Query: 286 FAASGTRNASQGAGSS---DTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASR 342
+ G R + G S ++SG S+ GQ T + Q + + +
Sbjct: 2457 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST--------SGQSSSCGQHGASSGQ 2508
Query: 343 TRSRSQTPNNTVTYESERGGFRRTFSRSERA---GVRTYVSTIRIPIRRILNTGLSETTS 399
+ S Q + + S+ G+ R S S ++ G R S + P +G ++S
Sbjct: 2509 SSSHGQHGSGS----SQSSGYGRQGSGSGQSPGHGQRGSGSR-QSPSYGRHGSGSGRSSS 2563
Query: 400 VAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRS-GRGGSGGGSSS--- 455
Q +G GE S F + +S S + S S S G+ GS G SS
Sbjct: 2564 SG------QHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE 2617
Query: 456 --GSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGR 513
GSSS SSS S S SS G S ++ S GS G SSS GR
Sbjct: 2618 RHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGR 2677
Score = 50.4 bits (119), Expect = 5e-06
Identities = 93/432 (21%), Positives = 154/432 (35%), Gaps = 42/432 (9%)
Query: 107 QTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGE 166
++G ++R + G+ S + SG + S +G Q S + + PS R
Sbjct: 1199 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSS-------GHGRQGSGSGHSPSRGRHGSG 1251
Query: 167 NVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAE 226
++S Q + S+S P S + + G A S+
Sbjct: 1252 LGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQG 1311
Query: 227 RSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQIS-GPELLSRGL 285
+ S S + + S ++ H ++ S RH Q S G G
Sbjct: 1312 QHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGH 1371
Query: 286 FAASGTRNASQGAGSSDT---AASGESTGSGQRPPTIVLDLQVRRVRPG--------EYR 334
++ G + G SS + SG+S+G G + + G ++
Sbjct: 1372 SSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHG 1431
Query: 335 QRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGL 394
R +SR + ++ +Y G R++ + + P R +G
Sbjct: 1432 SRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS---PSRGRHGSGS 1488
Query: 395 SETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGG--G 452
+++S + +G S + S E +GS + + ESRSG+ G G
Sbjct: 1489 GQSSSYS----------PYGSGSGWSSSRGPYE-SGSSHSSGLGHRESRSGQSSGYGQHG 1537
Query: 453 SSSGSSSSSSSSSSSSSSSSS------SSSPSSSSGGESSETS-SDLFEGSNEGSSSSGS 505
SSSG SS+ S+S SSS SS SSS G S +S S + GS S
Sbjct: 1538 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG 1597
Query: 506 SGARREGRHRAP 517
G R G ++P
Sbjct: 1598 HGQRGSGSRQSP 1609
Score = 50.1 bits (118), Expect = 6e-06
Identities = 105/456 (23%), Positives = 162/456 (35%), Gaps = 68/456 (14%)
Query: 83 NRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEIN 142
+R G SS G S G+++ GQ G+ S +++ + SG +
Sbjct: 496 SRSGQSSRGERQGSS----------AGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSR 545
Query: 143 VNRNNGSQNSEN---ENEPSARRSSGENVENNSQRQVENPRSESTSARPSR-SERNSTEA 198
+GS+ S + S R SS E+ S ES S + S + S+
Sbjct: 546 GRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSG 605
Query: 199 LTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNE 258
+ G +S S + S H S SSQ+ +
Sbjct: 606 HSSTHGQHGSTSGQSSSCGQHGATSGQSSSHG-----------QHGSGSSQSSRYGQQGS 654
Query: 259 TEGSS--RTRHHVTLRQQIS-GPELLSRGLFAASGTRNA--SQGAGSSDTAASGESTGSG 313
G S R RH S G G +++G + Q +G + SG+S+G
Sbjct: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
Query: 314 QRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERA 373
Q R+ + R +SR+ + + +Y G ++ S R
Sbjct: 715 QHGSGSSHSSGYRK-----HGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQS-SGHGRQ 768
Query: 374 GVRTYVSTIRIPIRRILNTGLSET-----TSVAIQTMLRQIMTGFGELSYFMYSDSDSEP 428
G + S R+ R ++G S + + + + +G G+ S F
Sbjct: 769 GSGSGHSPSRV--RHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGF--------- 817
Query: 429 TGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESS-- 486
+ ES SG+G S GS+SG SS S+S SSSS SSSG SS
Sbjct: 818 ---------GQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYG 868
Query: 487 --ETSSDLFEGSNEGSSSSGSS---GARREGRHRAP 517
E++S G S SG S G R G ++P
Sbjct: 869 QHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP 904
Score = 49.3 bits (116), Expect = 1e-05
Identities = 101/445 (22%), Positives = 155/445 (34%), Gaps = 43/445 (9%)
Query: 108 TGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARR--SSG 165
+G+++ GQ G+ S R+ SR S S+ +G ++ +++ + S G
Sbjct: 2192 SGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQG 2251
Query: 166 ENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARS-RSPDHRRTRAR 224
++ + Q + ST S + S + + + GQ+ + S +SP R +
Sbjct: 2252 QHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSS---SYGQQGSGSGQSPSRGRHGSG 2308
Query: 225 AERSRSPLHP------MSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGP 278
+ S S S R S S F H + + S T+H S
Sbjct: 2309 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYE 2368
Query: 279 ELLSRGLFAASGTRNASQGAGSSDTAASG----ESTGSGQRPPTIVLDLQVRRVRPGEYR 334
+ SR ++ G R+ S SS G +S G GQ R R G
Sbjct: 2369 QHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 2428
Query: 335 QRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGL 394
+ S S S S ++ YES G R R+G + G
Sbjct: 2429 GQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ 2488
Query: 395 SETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTG-----SVSNRNMERAE-------- 441
+TS + + + S+ + S+ +G S S ++ +
Sbjct: 2489 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 2548
Query: 442 -------------SRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSG-GESSE 487
S SG+ GSG G SSG SSS SSS S S SSG G+
Sbjct: 2549 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 2608
Query: 488 TSSDLFEGSNEGSSSSGSSGARREG 512
S G GSSS SS + G
Sbjct: 2609 RSGQSSRGERHGSSSGSSSHYGQHG 2633
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/192 (23%), Positives = 80/192 (41%), Gaps = 18/192 (9%)
Query: 327 RVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTI--RI 384
++R ++ ++ + ++ ++ ++ S G ++SR+ R ++ +I R+
Sbjct: 100 KLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRL 159
Query: 385 PIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRS 444
+R + + S + Q+ + +GE + + S GS S ++ + S
Sbjct: 160 SFQRDFS---GQHNSYSGQS------SSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGS 210
Query: 445 GRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSG 504
G G S + GS S SS S SSS SS S G S +S GS G SS G
Sbjct: 211 GSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRG 270
Query: 505 SSGARREGRHRA 516
RHR+
Sbjct: 271 E-------RHRS 275
Score = 47.0 bits (110), Expect = 5e-05
Identities = 70/292 (23%), Positives = 108/292 (36%), Gaps = 40/292 (13%)
Query: 243 HHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSD 302
H+S S Q+ + N S R S P G + + N + G+GS
Sbjct: 169 HNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQS-PNYGQHGSGSGQSSSNDTHGSGSGQ 227
Query: 303 TA-------ASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVT 355
++ +SG+S+G Q G++ R +SR + ++ +
Sbjct: 228 SSGFSQHKSSSGQSSGYSQHGSG-----SGHSSGYGQHGSRSGQSSRGERHRSSSGSSSS 282
Query: 356 YESERGGFRRTFSRSER-AGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFG 414
Y G R++ + +G R S +R +G ++S G
Sbjct: 283 YGQHGSGSRQSLGHGRQGSGSRQSPSHVRH------GSGSGHSSSHGQH----------G 326
Query: 415 ELSYFMYSDSDSEPTGSVSNRNMERAESRSGRG------GSGGGSSSGSSSSSSSSSSSS 468
S + YS E +GS + ES SG+ GSG G SS S+S +S
Sbjct: 327 SGSSYSYSRGHYE-SGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQAS 385
Query: 469 SSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSS---GARREGRHRAP 517
SS SS SS E++S G + SS SG S G R G ++P
Sbjct: 386 SSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSP 437
Score = 46.6 bits (109), Expect = 7e-05
Identities = 115/493 (23%), Positives = 174/493 (35%), Gaps = 66/493 (13%)
Query: 74 GPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQ----TGNTTRSGQRGNQSWRAVSRTN 129
G P G S S W +S + +G ++ G + SW++ T
Sbjct: 1357 GQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQ 1416
Query: 130 PNSGD-FRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSAR- 187
SG S E + +R+ S E S SS + S++ + + + S S +
Sbjct: 1417 HGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1476
Query: 188 --PSRSERNST--EALTEVPPTRGQRRARSRSP-----------DHRRTRARAERSRSPL 232
PSR S ++ + P G + SR P HR +R+ + S
Sbjct: 1477 PSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRS-GQSSGYGQ 1535
Query: 233 HPMSE---IPRRSHHSISSQTFEHPLVNETEGSSRTR-HHVTLRQQISG----------- 277
H S H S S Q+ + G S + H + Q SG
Sbjct: 1536 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS 1595
Query: 278 PELLSRGLFAASGTRNASQGAGSSDTAASG-------ESTGSGQRPPTIVLDLQVRRVRP 330
P RG + G+GS +++SG ES+G G + +
Sbjct: 1596 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 1655
Query: 331 GE-----YRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIP 385
G Y Q S + ++ SR + ++ + S R G + SR R + + P
Sbjct: 1656 GSGHSSGYGQHGSRSGQS-SRGERHGSS-SRSSSRYGQHGSGSRQSSGHGRQGSGSGQSP 1713
Query: 386 IRRILNTGLSETTSVAIQTMLRQIMTGFGELS----YFMYSDSDSEPTGSVSNRNMERAE 441
R +GL ++S Q +G G S Y S S S A
Sbjct: 1714 SRGRHGSGLGHSSSHG------QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAY 1767
Query: 442 SRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSS 501
S+ G GSG S G S+S SS+ SS+ SSS G S +S + S+ G
Sbjct: 1768 SQHG-SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS----QSSSYGQQ 1822
Query: 502 SSGSSGARREGRH 514
SGS + GRH
Sbjct: 1823 GSGSGQSPSRGRH 1835
Score = 46.2 bits (108), Expect = 9e-05
Identities = 95/414 (22%), Positives = 143/414 (34%), Gaps = 72/414 (17%)
Query: 108 TGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGEN 167
+G ++ GQ G S ++ S SG + S G Q S + PS R +
Sbjct: 617 SGQSSSCGQHGATSGQSSSHGQHGSGSSQSS-------RYGQQGSGSGQSPSRGRHGSDF 669
Query: 168 VENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAER 227
++S Q + S+S P S + G + +S + + + +
Sbjct: 670 GHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGF-------GHKSGSGQSSGYSQHGSGSSH 722
Query: 228 SRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFA 287
S R H S S Q SSR+ H + S GL +
Sbjct: 723 SSG---------YRKHGSRSGQ------------SSRSEQHGS-----------SSGLSS 750
Query: 288 ASGTRNASQGAGSSDTAASG-ESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSR 346
+ G G+GS ++ G + +GSG P RVR G S + S
Sbjct: 751 SYG----QHGSGSHQSSGHGRQGSGSGHSPS---------RVRHGSSSGHSSSHGQHGSG 797
Query: 347 SQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTML 406
+ ++ YES G F + E + Y S + G +TS +
Sbjct: 798 TSCSSSCGHYESGSGQ-ASGFGQHESGSGQGY-SQHGSASGHFSSQGRHGSTSGQSSSSG 855
Query: 407 RQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSS-------SGSSS 459
+ + SY + + +G + + G+ GSG G S SGS
Sbjct: 856 QHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGR 915
Query: 460 SSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGR 513
SSSS S S SS SS G+SS + GS G SSS R G+
Sbjct: 916 SSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQ---HGSGSGHSSSYEQHGSRSGQ 966
Score = 45.4 bits (106), Expect = 2e-04
Identities = 102/426 (23%), Positives = 157/426 (36%), Gaps = 60/426 (14%)
Query: 115 GQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNN---GSQNSENENEPSARRSSGENVENN 171
G R QS R + + R+ + +R + G Q S + + PS R + ++
Sbjct: 2137 GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSS 2196
Query: 172 SQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSP 231
S Q + S+S P S + GQ + S + A ++
Sbjct: 2197 SHGQHGSGSGRSSSRGPYESRSGHSSVF-------GQHESGSG-----HSSAYSQHGSGS 2244
Query: 232 LHPMSEIPRRSHHSISSQ--TFEHPLVNETEGSSRTRH------HVTLRQQISGP-ELLS 282
H S+ H S S Q TF+ + + SS +H + QQ SG + S
Sbjct: 2245 GHFCSQ---GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPS 2301
Query: 283 RGLFAASGTRNAS---QGAGSSDTAASGE-STGSGQRPPTIVLDLQVRRVRPGEYRQRDS 338
RG + ++S G+GS +++SG +GSGQ G +
Sbjct: 2302 RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF------------GHHESSSW 2349
Query: 339 IASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIR----IPIRRILNTGL 394
+S ++ +YE + G SR ER G + S+ R+ L G
Sbjct: 2350 QSSGYTQHGSGSGHSSSYE-QHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408
Query: 395 SETTSVAIQTMLR-QIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGS 453
+ S + R + +G G+ S + P GS S + R SG G S G
Sbjct: 2409 HGSGSGQSPSPSRGRHGSGSGQSSSY-------SPYGSGSGWSSSRGPYESGSGHSSGLG 2461
Query: 454 SSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSS----GSSGAR 509
S S SS SSS SS G S ++SS G++ G SSS GS ++
Sbjct: 2462 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2521
Query: 510 REGRHR 515
G R
Sbjct: 2522 SSGYGR 2527
Score = 45.1 bits (105), Expect = 2e-04
Identities = 102/430 (23%), Positives = 149/430 (34%), Gaps = 49/430 (11%)
Query: 108 TGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGEN 167
+G + GQRG+ S ++ S SG R S G + +E S+ +SS +
Sbjct: 1122 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1181
Query: 168 VENNSQRQVEN-PRSESTSARPSRSERNSTEALTEVPPTRGQRRARSR-SPDHRRTRARA 225
+ + S S + SR ER+ + + + GQ + SR S H R + +
Sbjct: 1182 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS--SHYGQHGSGSRQSSGHGRQGSGS 1239
Query: 226 ERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGL 285
S S R H S + H G S +R GP G
Sbjct: 1240 GHSPS---------RGRHGSGLGHSSSHGQHGSGSGRSSSR----------GPYESRSGH 1280
Query: 286 FAASGTRNASQG---AGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASR 342
+ G + G A S + SG GQ T + + Q S +
Sbjct: 1281 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST--------SGQSSTFDQEGSSTGQ 1332
Query: 343 TRS---RSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTS 399
+ S R + + Y G ++ SR + S+ +G ++S
Sbjct: 1333 SSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQH-----GSGSGWSSS 1387
Query: 400 VAIQTMLRQIMTGFG--ELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGG--GSSS 455
+GFG E S + S +GS + + E+ SRSG+ G GSSS
Sbjct: 1388 SGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS 1447
Query: 456 GSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHR 515
GSSSS S S S S SG S + GS + SS S R
Sbjct: 1448 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSR 1507
Query: 516 APVTFDESGS 525
P ESGS
Sbjct: 1508 GPY---ESGS 1514
Score = 45.1 bits (105), Expect = 2e-04
Identities = 100/438 (22%), Positives = 150/438 (34%), Gaps = 48/438 (10%)
Query: 107 QTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSS-- 164
++G+++ GQ + S + + + SG F + +G ++ ++ S +SS
Sbjct: 1747 RSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 1806
Query: 165 GENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRAR 224
G++ +SQ + + PSR S + G S S + +
Sbjct: 1807 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS- 1865
Query: 225 AERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRG 284
+ HH SS T+ S + H + Q S SRG
Sbjct: 1866 -----------GQSSGFGHHESSSWQSS----GYTQHGSGSGHSSSYEQHGSRSGQSSRG 1910
Query: 285 LFAASGTRNASQ----GAGSSDTAASGE-STGSGQRPPTIVLDLQVRRVRPGEYRQRDSI 339
S + ++S G+GS + G+ +GSGQ P R R G + S
Sbjct: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP-------SRGRHGSGSGQSSS 1963
Query: 340 ASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTS 399
S S ++ YES G R R+G + + ++G S T
Sbjct: 1964 YGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG------QHGSSSGHSSTHG 2017
Query: 400 VAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSS 459
+ G S S +GS + R S SG+ G SGS
Sbjct: 2018 QHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQ 2077
Query: 460 SSSSSSSSSSSSSSSSSPSSSSG-GESS----------ETSSDLFEGSNEGSSSS-GSSG 507
S S S S SSSS G GESS ++SS GS G SS G G
Sbjct: 2078 SPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG 2137
Query: 508 ARREGRHRAPVTFDESGS 525
+R R SGS
Sbjct: 2138 SRSGQSSRGERHGSSSGS 2155
Score = 43.9 bits (102), Expect = 4e-04
Identities = 109/505 (21%), Positives = 168/505 (33%), Gaps = 76/505 (15%)
Query: 54 GTPGESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQ----TG 109
G G + + Q G P G S S W +S + +G
Sbjct: 2277 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
Query: 110 NTTRSGQRGNQSWRAVSRTNPNSGD-FRFSLEINVNRNNGSQNSENENEPSARRSSGENV 168
++ G + SW++ T SG S E + +R+ S E S SS
Sbjct: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQH 2396
Query: 169 ENNSQRQVENPRSESTSAR---PSRSERNST--EALTEVPPTRGQRRARSRSPDHRRTRA 223
+ S++ + + + S S + PSR S ++ + P G + SR P +
Sbjct: 2397 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGP----YES 2452
Query: 224 RAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSR 283
+ S H S + S + + H + GS+ + + S + S
Sbjct: 2453 GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH 2512
Query: 284 GLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRT 343
G + ++++ G S SG+S G GQR R P Y + S + R+
Sbjct: 2513 GQHGSGSSQSSGYGRQGS---GSGQSPGHGQRGSG-------SRQSPS-YGRHGSGSGRS 2561
Query: 344 RSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQ 403
S Q + E GF S S ++ + + +G S
Sbjct: 2562 SSSGQHGSGL----GESSGFGHHESSSGQSSSYSQHGS---------GSGHS-------- 2600
Query: 404 TMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAE------SRSGRGGSGGGS---- 453
+G+G+ S E GS S + + SG G G GS
Sbjct: 2601 -------SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP 2653
Query: 454 SSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSS---------SSG 504
S G S SSS S S SSS G S G +E S SG
Sbjct: 2654 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713
Query: 505 SSGARREGRHRA----PVTFDESGS 525
S +G+H + TFD+ GS
Sbjct: 2714 SGHFCSQGQHGSTSGQSSTFDQEGS 2738
Score = 40.8 bits (94), Expect = 0.004
Identities = 101/432 (23%), Positives = 157/432 (36%), Gaps = 53/432 (12%)
Query: 107 QTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGE 166
++G ++RS Q G+ S + S SG R SL + +GS + ++ + R SG
Sbjct: 963 RSGQSSRSEQHGSSSGSSSSYGQHGSGS-RQSLG---HGQHGSGSGQSPSPSRGRHGSGS 1018
Query: 167 NVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSR---SPDHRRTRA 223
+++S + S+S P S + L GQ + S H T
Sbjct: 1019 G-QSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 1077
Query: 224 R-----AERSRSPLHPMSEIPRRSHH---SISSQTFEHPLVNETEGSSRTRHHVTLRQQI 275
+ + S H S SH S SSQ+ + + GS ++ H Q+
Sbjct: 1078 QHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG--RQGSGSGQSPGH---GQRG 1132
Query: 276 SGP-ELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPG--- 331
SG + S G + R++S G S GES+G G + + G
Sbjct: 1133 SGSRQSPSYGRHGSGSGRSSSSGQHGSGL---GESSGFGHHESSSGQSSSYSQHGSGSGH 1189
Query: 332 -----EYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPI 386
++ R +SR + ++ Y G R++ + + P
Sbjct: 1190 SSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS-----GSGHSPS 1244
Query: 387 RRILNTGLSETTSVAIQTMLRQIMTGFGELS----YFMYSDSDSEPTGSVSNRNMERAES 442
R +GL ++S Q +G G S Y S S S A S
Sbjct: 1245 RGRHGSGLGHSSSHG------QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYS 1298
Query: 443 RSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSS 502
+ G GSG S G S+S SS+ SS+ SSS G S +S + S G
Sbjct: 1299 QHG-SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS----QSSGYGRHG 1353
Query: 503 SGSSGARREGRH 514
+GS + GRH
Sbjct: 1354 AGSGQSPSRGRH 1365
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 65.1 bits (157), Expect = 2e-10
Identities = 43/100 (43%), Positives = 56/100 (56%), Gaps = 6/100 (6%)
Query: 425 DSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSS------SSSSPS 478
+S+ +R+ RA +++ + S SSS SSSSS+SSSS SSSSS SSSS S
Sbjct: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
Query: 479 SSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPV 518
SS+ G SS SS S+E S S G R+ +HR V
Sbjct: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSV 650
Score = 63.5 bits (153), Expect = 5e-10
Identities = 43/93 (46%), Positives = 53/93 (56%), Gaps = 3/93 (3%)
Query: 427 EPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESS 486
EP +V + + ++RS G +S S S SSSSSSSSSSS+SSSS SSSS G SS
Sbjct: 543 EPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
Query: 487 ETSSDLFEGSNEGSS---SSGSSGARREGRHRA 516
SS S GSS SS S+ + E R R+
Sbjct: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRS 635
Score = 39.3 bits (90), Expect = 0.011
Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 4/94 (4%)
Query: 422 SDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSS-SSSSSSSSSSSSSSSSSPSSS 480
S S S T S S + S S S S+SGSSS SSSS+SSSS S S S
Sbjct: 581 SSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGH 640
Query: 481 SGGESSETSSDLFEGSNEG---SSSSGSSGARRE 511
+ S D G S S G+ R+
Sbjct: 641 NRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRD 674
Score = 37.7 bits (86), Expect = 0.032
Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 25/134 (18%)
Query: 112 TRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENN 171
TRS RG RA ++T+ +R+ S +S + + ++ S + +
Sbjct: 558 TRSRSRG----RARNKTSK-------------SRSRSSSSSSSSSSSTSSSSGSSSSSGS 600
Query: 172 SQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSP 231
S + + S STS SR +ST + +E +R + R +R HRR+ R R S
Sbjct: 601 SSSRSSSSSSSSTSGSSSRDSSSSTSSSSE-SRSRSRGRGHNRDRKHRRSVDRKRRDTSG 659
Query: 232 LHPMSEIPRRSHHS 245
L RSH S
Sbjct: 660 L-------ERSHKS 666
Score = 36.6 bits (83), Expect = 0.071
Identities = 47/176 (26%), Positives = 73/176 (41%), Gaps = 17/176 (9%)
Query: 199 LTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNE 258
LT P ++ + + RSRS R + RSRS S S SS T +
Sbjct: 546 LTVHPESKSKTKTRSRSRGRARNKTSKSRSRS---------SSSSSSSSSSTSSSSGSSS 596
Query: 259 TEGSSRTRHHVTLRQQISGPEL--LSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRP 316
+ GSS +R + SG S ++S +R+ S+G G + S +R
Sbjct: 597 SSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSV-DRKRR 655
Query: 317 PTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSER 372
T L+ + + G RD+ S+ ++ +++ ES R G R SRSER
Sbjct: 656 DTSGLERSHKSSKGGS--SRDTKGSKDKNSRSDRKRSIS-ESSRSGKRS--SRSER 706
Score = 30.0 bits (66), Expect = 6.7
Identities = 32/145 (22%), Positives = 61/145 (42%), Gaps = 4/145 (2%)
Query: 78 QNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRF 137
++S + SS S+G S +S R + +++ S G+ S + S T+ +S
Sbjct: 576 RSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSR 634
Query: 138 SLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTE 197
S NR+ + S + R +SG + S + + ++ + + SRS+R +
Sbjct: 635 SRGRGHNRDRKHRRSVDRKR---RDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSI 691
Query: 198 ALTEVPPTRGQRRARSRSPDHRRTR 222
+ + R R R R D + R
Sbjct: 692 SESSRSGKRSSRSERDRKSDRKDKR 716
>gi|150170725 zinc and ring finger 4 [Homo sapiens]
Length = 429
Score = 64.3 bits (155), Expect = 3e-10
Identities = 24/50 (48%), Positives = 37/50 (74%), Gaps = 2/50 (4%)
Query: 570 CSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSE--NSTCPICRRAVLAS 617
C++C+ EY EG++L+ LPCSH YH CID W S+ +CP+C+++V A+
Sbjct: 309 CAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSVAAT 358
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 63.9 bits (154), Expect = 4e-10
Identities = 78/331 (23%), Positives = 133/331 (40%), Gaps = 37/331 (11%)
Query: 72 KEGPPPQNSDENRGGDSS--DDVSNGDSIIDWLNSVRQTGNTTRSGQRG----------- 118
KE PPP G S+ +D++ D + L + + R+G G
Sbjct: 1706 KEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDR 1765
Query: 119 --------NQSWRAVSRTNPNSGDFRFSLEI---------NVNRNNGSQNSENENEPSAR 161
+ RA ++ D+ +++ N NR+ G + + ++ +R
Sbjct: 1766 SAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSR 1825
Query: 162 RSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDH-RR 220
++ E+ S+++ RS + R S+S+ + ++ + R +R +RSRS RR
Sbjct: 1826 SKRSKSSEHKSRKRTSESRSRARK-RSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884
Query: 221 TRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPEL 280
+ ++ +R RSP H R+ S S + S R+R H R++ S +
Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS-RSV 1943
Query: 281 LSRGLFAASGTRNASQGAGSSDTAASGESTGSGQ-RPPTIVLDLQVRRVRPGEYRQRDSI 339
R F+ S +R + + S T + T S + R P+ RR R R+R
Sbjct: 1944 GRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Query: 340 ASRTRSRSQTPNNTVTYESERGGFRRTFSRS 370
R RS S +P V R RR FSRS
Sbjct: 2004 VVRRRSFSISP---VRLRRSRTPLRRRFSRS 2031
Score = 33.5 bits (75), Expect = 0.60
Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 6/126 (4%)
Query: 112 TRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENN 171
+R+ R ++S R S R S I+ +R + + + + R+
Sbjct: 1922 SRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1981
Query: 172 SQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQR------RARSRSPDHRRTRARA 225
S+R R T +R RS + P R +R R SRSP R+ +
Sbjct: 1982 SRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSS 2041
Query: 226 ERSRSP 231
ER RSP
Sbjct: 2042 ERGRSP 2047
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 63.9 bits (154), Expect = 4e-10
Identities = 78/331 (23%), Positives = 133/331 (40%), Gaps = 37/331 (11%)
Query: 72 KEGPPPQNSDENRGGDSS--DDVSNGDSIIDWLNSVRQTGNTTRSGQRG----------- 118
KE PPP G S+ +D++ D + L + + R+G G
Sbjct: 1706 KEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDR 1765
Query: 119 --------NQSWRAVSRTNPNSGDFRFSLEI---------NVNRNNGSQNSENENEPSAR 161
+ RA ++ D+ +++ N NR+ G + + ++ +R
Sbjct: 1766 SAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSR 1825
Query: 162 RSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDH-RR 220
++ E+ S+++ RS + R S+S+ + ++ + R +R +RSRS RR
Sbjct: 1826 SKRSKSSEHKSRKRTSESRSRARK-RSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884
Query: 221 TRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPEL 280
+ ++ +R RSP H R+ S S + S R+R H R++ S +
Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS-RSV 1943
Query: 281 LSRGLFAASGTRNASQGAGSSDTAASGESTGSGQ-RPPTIVLDLQVRRVRPGEYRQRDSI 339
R F+ S +R + + S T + T S + R P+ RR R R+R
Sbjct: 1944 GRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Query: 340 ASRTRSRSQTPNNTVTYESERGGFRRTFSRS 370
R RS S +P V R RR FSRS
Sbjct: 2004 VVRRRSFSISP---VRLRRSRTPLRRRFSRS 2031
Score = 33.5 bits (75), Expect = 0.60
Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 6/126 (4%)
Query: 112 TRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENN 171
+R+ R ++S R S R S I+ +R + + + + R+
Sbjct: 1922 SRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1981
Query: 172 SQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQR------RARSRSPDHRRTRARA 225
S+R R T +R RS + P R +R R SRSP R+ +
Sbjct: 1982 SRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSS 2041
Query: 226 ERSRSP 231
ER RSP
Sbjct: 2042 ERGRSP 2047
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 62.8 bits (151), Expect = 9e-10
Identities = 104/445 (23%), Positives = 164/445 (36%), Gaps = 57/445 (12%)
Query: 110 NTTRSGQ----RGNQSWRAVSRTNPNSGDFR------------FSLEINVNRNNGSQNSE 153
+TT G+ RG R+ SRT N R S +++R++ + +
Sbjct: 873 HTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQ 932
Query: 154 NENEPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARS 213
+E ++RR G +V +S + + SE S SR+ R S + + G R RS
Sbjct: 933 SEGSRTSRRQ-GSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSR----HGSRHPRS 987
Query: 214 RSPDHRRTRARAERSRSPLHPMSEIPR-----RSHHSISSQTFEHPLVNETEGSSRTRHH 268
D A+ SR P +E SH S E + + +RH
Sbjct: 988 HHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHS 1047
Query: 269 VTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRV 328
R+Q S + G + +SG++ AS G S+ + + +G GQ P + R
Sbjct: 1048 GIPRRQASSA-VRDSGHWGSSGSQ-ASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARD 1105
Query: 329 RPG--------------EYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAG 374
G + Q +S RTR+ + + +E R R + S+ +
Sbjct: 1106 WSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGS-HHEQARDSSRHSASQEGQDT 1164
Query: 375 VRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTG--FGELSYFMYSDSDSEPTGSV 432
+R + + RR G SV R +G + SD+ +GS
Sbjct: 1165 IRAHPGS-----RRGGRQGSHHEQSVD-----RSGHSGSHHSHTTSQGRSDASHGQSGSR 1214
Query: 433 SNRNMERAESRSGRGG--SGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSS 490
S R + +SG G SG +S + SS S SS S +S G S S
Sbjct: 1215 SASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDS 1274
Query: 491 DLFEGSNEGSSSSGSSGARREGRHR 515
D S++ SGS+ G R
Sbjct: 1275 DSERHSDDSERLSGSASRNHHGSSR 1299
Score = 58.5 bits (140), Expect = 2e-08
Identities = 113/488 (23%), Positives = 178/488 (36%), Gaps = 74/488 (15%)
Query: 93 SNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGD---------FRFSLEINV 143
S+G S ++ Q + GQ G++S +R SGD S ++
Sbjct: 3132 SSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADI 3191
Query: 144 NRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVP 203
+R++ + ++E +RR G +V +S + + SE S SR+ R S + +
Sbjct: 3192 SRHSQAVQGQSEGSRRSRRQ-GSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSR-- 3248
Query: 204 PTRGQRRARSRSPD-----HRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNE 258
G R RS D H R+R +R SH S E
Sbjct: 3249 --HGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRH 3306
Query: 259 TEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPT 318
+ + +RH R Q S SR + +SG++ AS G S+ + + +G GQ P
Sbjct: 3307 QQSADSSRHSGIPRGQASSAVRDSRH-WGSSGSQ-ASDSEGHSEESDTQSVSGHGQAGPH 3364
Query: 319 IVLDLQVRRVRPG--------------EYRQRDSIASRTR-------------------- 344
+ R R G + Q +S RTR
Sbjct: 3365 QQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRH 3424
Query: 345 SRSQTPNNTVTYE---SERGG----FRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSET 397
S SQ +T+ S RG + ++ RS +G ++ S R + G S +
Sbjct: 3425 SASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSG--SHHSHTTSQGRSDASRGQSGS 3482
Query: 398 TSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGS 457
S + QT + G+ S +S T + S+R+ S+SG+G S G +S
Sbjct: 3483 RSASRQTRNDEQS---GDGSRHSWSHHHEASTQADSSRH-----SQSGQGQSAGPRTS-- 3532
Query: 458 SSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAP 517
+ SS S S S S SG S E S +GS S R G +
Sbjct: 3533 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSA 3592
Query: 518 VTFDESGS 525
+ +SG+
Sbjct: 3593 ESSRQSGT 3600
Score = 57.0 bits (136), Expect = 5e-08
Identities = 114/484 (23%), Positives = 173/484 (35%), Gaps = 79/484 (16%)
Query: 58 ESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVS-NGDSIIDWLNSVRQTGNTTRSGQ 116
+S+ + Q G P + +G V +G S ++ Q + GQ
Sbjct: 2124 DSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQ 2183
Query: 117 RGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQV 176
G++S + SGD +R++GS + E + + R S +S +
Sbjct: 2184 SGSRSASRKTYDKEQSGDG--------SRHSGSHHHEASSWADSSRHSLVGQGQSSGPRT 2235
Query: 177 ENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMS 236
PR S S + S SE +S ++ +RR+ S S +H + R S HP S
Sbjct: 2236 SRPRGSSVS-QDSDSEGHSEDS---------ERRSGSASRNHHGSAQEQSRDGSR-HPRS 2284
Query: 237 EIPRRSHHSISS----QTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTR 292
R+ H S+ Q+ H N + G + + H + +G S +A +R
Sbjct: 2285 HHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQA--RSSAGERHGSHHQQSADSSR 2342
Query: 293 NASQGAGSSDTAA--SGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQT- 349
++ G G + +A SG SG + E DS + Q
Sbjct: 2343 HSGIGHGQASSAVRDSGHRGSSGSQ------------ASDSEGHSEDSDTQSVSAHGQAG 2390
Query: 350 PNNTVTYESERGGFRRTFSRSERAGVRTY-VSTIRIPIRRILNTGLSETTSVAIQTMLRQ 408
P+ ES RG R+ RS R+G Y VST TG S
Sbjct: 2391 PHQQSHQESTRG---RSAGRSGRSGSFLYQVSTHEQSESAHGRTGTS------------- 2434
Query: 409 IMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGS--------SSS 460
TG + S+ + S + S E ++ G GS G GS S
Sbjct: 2435 --TGGRQGSHHKQARDSSRHSTS-----QEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGH 2487
Query: 461 SSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTF 520
S S S ++S S + SG S+ + E S +GS SGS H A
Sbjct: 2488 SGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSR------HHEASSRA 2541
Query: 521 DESG 524
D SG
Sbjct: 2542 DSSG 2545
Score = 56.6 bits (135), Expect = 7e-08
Identities = 106/459 (23%), Positives = 161/459 (35%), Gaps = 82/459 (17%)
Query: 80 SDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSL 139
SD +RG S S RQT N +SG SW S S
Sbjct: 3473 SDASRGQSGSRSAS------------RQTRNDEQSGDGSRHSW---------SHHHEAST 3511
Query: 140 EINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTEAL 199
+ + +R++ S ++ P R+ G +V +S Q + SE S SR+ R S +
Sbjct: 3512 QADSSRHSQSGQGQSAG-PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQ 3570
Query: 200 TEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNET 259
+ G R S D AE SR +HH+ +S + +E
Sbjct: 3571 SR----DGSRHPTSHHEDRAGHGHSAESSRQS---------GTHHAENSSGGQAASSHEQ 3617
Query: 260 EGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAA--SGESTGSGQRPP 317
SS H + QQ +A +R++ G G + +A SG SG +
Sbjct: 3618 ARSSAGERHGSHHQQ------------SADSSRHSGIGHGQASSAVRDSGHRGSSGSQ-- 3663
Query: 318 TIVLDLQVRRVRPGEYRQRDSIASRTRSRSQT-PNNTVTYESERGGFRRTFSRSERAG-- 374
E DS + Q P+ ES RG R+ RS R+G
Sbjct: 3664 ----------ASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRG---RSAGRSGRSGSF 3710
Query: 375 ---VRTYVSTIRIPIRRILNTGLSE-TTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTG 430
V T+ + R +TG + + + R + G+ + + S G
Sbjct: 3711 LYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRR---G 3767
Query: 431 SVSNRNMERAESRSGRGGS--------GGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSG 482
E++ RSG GS G +S S S S+S + + S S SG
Sbjct: 3768 GRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSG 3827
Query: 483 GESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFD 521
E S+ + S S+G+RR R + V+ D
Sbjct: 3828 SRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQD 3866
Score = 55.8 bits (133), Expect = 1e-07
Identities = 114/536 (21%), Positives = 197/536 (36%), Gaps = 68/536 (12%)
Query: 4 SDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLM---RDNNLLGTPGEST 60
SD +GS A+ + D + L ++ ++ R G G S
Sbjct: 410 SDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSL 469
Query: 61 EEELLRRLQQIKEGPPPQNSDENRGG--DSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRG 118
+ G ++ +G + + D S + + +++R ++R G++G
Sbjct: 470 YQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQG 529
Query: 119 NQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSAR----RSSGENVENNSQR 174
+ ++V+R+ +SG S + R++ S S + SG+ ++ R
Sbjct: 530 SHHEQSVNRSG-HSGSHH-SHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSR 587
Query: 175 QVENPRSESTSARPS----------RSERNSTEALTEVPPTRG-----QRRARSRSPDHR 219
E S++ S+R S R+ RN ++++ ++G +R + S S +H
Sbjct: 588 HHE-ASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHH 646
Query: 220 RTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTR---HHVTLRQQIS 276
+ R S HP S R+ H S+ + T+ SS + H R
Sbjct: 647 GSAQEQSRDGSR-HPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAG 705
Query: 277 GPELLSRGLFAASGTRNASQGAGSSDTAA--SGESTGSGQRPPTIVLDLQVRRVRPGEYR 334
L +A +R++ G G + +A SG SG + E
Sbjct: 706 ERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQ------------ATDSEGH 753
Query: 335 QRDSIASRTRSRSQTPNNTVTY-ESERGGFRRTFSRSERAGVRTY-VSTIRIPIRRILNT 392
DS Q ++ ++ ES R R+ RS R+G Y VST + T
Sbjct: 754 SEDSDTQSVSGHGQAGHHQQSHQESARD---RSGERSRRSGSFLYQVSTHKQSESSHGWT 810
Query: 393 GLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAE---SRSGRGGS 449
G S TG + S+ + +S + S ++ R SR GR GS
Sbjct: 811 GPS---------------TGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGS 855
Query: 450 GGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGS 505
S S S S S ++S S + SG S+ ++ E S +GS SGS
Sbjct: 856 HHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGS 911
Score = 54.3 bits (129), Expect = 3e-07
Identities = 115/518 (22%), Positives = 186/518 (35%), Gaps = 65/518 (12%)
Query: 58 ESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDV-SNGDSIIDWLNSVRQTGNTTRSGQ 116
+S+ + Q G P + +G V S+G S ++ Q + GQ
Sbjct: 1799 DSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQ 1858
Query: 117 RGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQV 176
G++S +R SGD GS++S + + ++ R+ Q Q
Sbjct: 1859 SGSRSVSRQTRNEKQSGD-------------GSRHSGSRHHEASSRADSSRHSQVGQGQS 1905
Query: 177 ENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMS 236
PR+ S + S S+ + ++ +E +R + S S +H + R S HP S
Sbjct: 1906 SGPRT-SRNQGSSVSQDSDSQGHSE----DSERWSGSASRNHLGSAWEQSRDGSR-HPGS 1959
Query: 237 EIPRRSHHSISSQTFEHPLVNETEGSSRTR---HHVTLRQQISGPELLSRGLFAASGTRN 293
R+ H S+ + TE SSR + H R L +A +R+
Sbjct: 1960 HHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRH 2019
Query: 294 ASQGAGSSDTAA--SGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQT-P 350
+ G G + +A SG SG + E DS ++ + P
Sbjct: 2020 SGIGHGQASSAVRDSGHRGYSGSQ------------ASDSEGHSEDSDTQSVSAQGKAGP 2067
Query: 351 NNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIM 410
+ ES RG ++ S R+G Y ++ SE+T
Sbjct: 2068 HQQSHKESARG---QSGESSGRSGSFLY---------QVSTHEQSESTHGQSAPS----- 2110
Query: 411 TGFGELSYFMYSDSDSEPTGSVSNRNMERAE---SRSGRGGSGGGSSSGSSSSSSSSSSS 467
TG + S++ + S + S ++ R SR GR GS S S S S S
Sbjct: 2111 TGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSH 2170
Query: 468 SSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGS-----SGARREGRHRAPVTFDE 522
++S S + SG S+ + E S +GS SGS S RH
Sbjct: 2171 TTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQS 2230
Query: 523 SGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRS 560
SG P S + +++D D + E+ A R+
Sbjct: 2231 SG--PRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRN 2266
Score = 52.4 bits (124), Expect = 1e-06
Identities = 125/566 (22%), Positives = 207/566 (36%), Gaps = 80/566 (14%)
Query: 1 MENSDSNDKGSGDQSAAQRRSQM-DRLDREEAFYQFVNNLSEEDYRLMRDNNLL----GT 55
+E + N++G D R +Q + +Y + + L+ +N + +
Sbjct: 204 LEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSS 263
Query: 56 PGESTEEELLRRLQQIKEGPPPQNSDENRGGD--SSDDVSNGDSIIDWLNSVRQTGNTTR 113
G+S+ + R + + P ++ R G S D S G S +S R +G+ +R
Sbjct: 264 DGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSE----DSERHSGSASR 319
Query: 114 S--GQRGNQSWRAVSRTNPNSGDFRFSL--EINVNRNNGSQNSENENE------------ 157
+ G QS R SR + + R S + +R +G++++E +
Sbjct: 320 NHHGSAWEQS-RDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARS 378
Query: 158 -PSARRSSGENVENNSQRQVENPRSESTSARPSRSERNST-------EALTEVPPTR--- 206
P R SG +S R R +++SA R R S+ E +E T+
Sbjct: 379 SPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVS 438
Query: 207 GQRRARSRSPDHR-----RTRARAERSRSPLHPMS--EIPRRSHHSISSQTFEHPLVNET 259
G +A R H+ R+ R+ RS S L+ +S E P +H + T +
Sbjct: 439 GHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHE 498
Query: 260 EGSSRTRHHVTLRQQ--ISGPELLSRG-----LFAASGTRNASQGAGSSDTAASGESTGS 312
+ +RH + Q I G SRG S R+ G+ S T + G S S
Sbjct: 499 QARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDAS 558
Query: 313 GQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSER 372
+ + Q R R S + + SQ ++ S+ G + + R+ R
Sbjct: 559 HGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSR---HSQVGQGQSSGPRTSR 615
Query: 373 AGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSV 432
N G S + Q G S + S E +
Sbjct: 616 ------------------NQGSSVSQDSDSQGHSEDSERWSGSASR-NHHGSAQEQSRDG 656
Query: 433 SNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDL 492
S E R+G G S SS S + + +SSS ++SS + SS GE + L
Sbjct: 657 SRHPRSHHEDRAGHGHSA--DSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQL 714
Query: 493 FEGSNEGSSSSG---SSGARREGRHR 515
+ S +G +S A R+ HR
Sbjct: 715 QSADSSRHSGTGHGQASSAVRDSGHR 740
Score = 51.2 bits (121), Expect = 3e-06
Identities = 101/487 (20%), Positives = 175/487 (35%), Gaps = 80/487 (16%)
Query: 58 ESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVS-NGDSIIDWLNSVRQTGNTTRSGQ 116
+S+ + Q G P + +G V+ +G S ++ Q + GQ
Sbjct: 502 DSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQ 561
Query: 117 RGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENE----------------PSA 160
G++S +R SGD R++GS++ E ++ P
Sbjct: 562 SGSRSASRQTRNEEQSGDG--------TRHSGSRHHEASSQADSSRHSQVGQGQSSGPRT 613
Query: 161 RRSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPD--- 217
R+ G +V +S Q + SE S SR+ S + + G R RS D
Sbjct: 614 SRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSR----DGSRHPRSHHEDRAG 669
Query: 218 --HRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFE-HPLVNETEGSSRTRHHVTLRQQ 274
H +R +R + S SH S E H ++ + + +RH T Q
Sbjct: 670 HGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQ 729
Query: 275 ISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYR 334
S + G +SG++ A+ G S+ + + +G GQ + R R GE
Sbjct: 730 ASSA-VRDSGHRGSSGSQ-ATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERS 787
Query: 335 QRDS-----IASRTRSRSQT----PNNTVT----YESERGGFRRTFSRSERAGVRTYVST 381
+R +++ +S S P+ V +E R R + S+ + +R + +
Sbjct: 788 RRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGS 847
Query: 382 IRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAE 441
R + S+ S S +GS + +
Sbjct: 848 SRRGRQG----------------------------SHHEQSVDRSGHSGSHHSHTTSQGR 879
Query: 442 SRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSS 501
S + RG SG S+S ++ + S S S S +SS S + + +G +EGS
Sbjct: 880 SDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAG--QGQSEGSR 937
Query: 502 SSGSSGA 508
+S G+
Sbjct: 938 TSRRQGS 944
Score = 49.7 bits (117), Expect = 8e-06
Identities = 103/466 (22%), Positives = 167/466 (35%), Gaps = 99/466 (21%)
Query: 69 QQIKEGPPPQNSDENRGGDSSDDVS-NGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSR 127
Q G P + +G V +G S ++ Q + GQ G +S +R
Sbjct: 1486 QDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTR 1545
Query: 128 TNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSAR 187
SGD +R++GS++ +EPS R S R + + ES ++
Sbjct: 1546 NEEQSGDG--------SRHSGSRH----HEPSTRAGSS--------RHSQVGQGESAGSK 1585
Query: 188 PSRSERNST--EALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHS 245
SR + +S + +E +RR+ S S +H + AR + +P S R+ H
Sbjct: 1586 TSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGS-AREQSRHGSRNPRSHQEDRASHG 1644
Query: 246 ISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAA 305
S+++ E SS + + Q S P G R+ S+ S+D
Sbjct: 1645 HSAESSRQSGTRHAETSSGGQAASSQEQARSSP-----------GERHGSRHQQSAD--- 1690
Query: 306 SGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQ-TPNNTVTYESERGGFR 364
S +G+G+R + V+ R G S AS + S+ + +V+ + G +
Sbjct: 1691 SSTDSGTGRRQDSSVVGDSGNRGSSG------SQASDSEGHSEESDTQSVSAHGQAGPHQ 1744
Query: 365 RTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDS 424
++ S R G S S + L Q+ T
Sbjct: 1745 QSHQESTR--------------------GQSGERSGRSGSFLYQVSTH------------ 1772
Query: 425 DSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSS-----PSS 479
E++ES GR G G S + SS S+S P S
Sbjct: 1773 -------------EQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGS 1819
Query: 480 SSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGS 525
S GG +E S + S SGS + + R+ V+ +SGS
Sbjct: 1820 SRGGRQGSH----YEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGS 1861
Score = 45.1 bits (105), Expect = 2e-04
Identities = 87/415 (20%), Positives = 154/415 (37%), Gaps = 55/415 (13%)
Query: 114 SGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQ 173
SG RG S+ + N G S +V+ + + + + ++ SAR SGE
Sbjct: 2682 SGHRGYSG----SQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGET------ 2731
Query: 174 RQVENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPL- 232
+ S S + S E++ + P TRG++ +R + ++ + +
Sbjct: 2732 ----SGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIR 2787
Query: 233 -HPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGT 291
HP S R Q + H ++ G S + H T Q G SRG SG+
Sbjct: 2788 GHPGSSRGGR-------QGYHHEHSVDSSGHSGSHHSHTTSQ---GRSDASRG---QSGS 2834
Query: 292 RNASQGAGSSDTAASGES-TGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTP 350
R+AS+ + + + G +GS + D+ R + Q S SR RS+
Sbjct: 2835 RSASRTTRNEEQSGDGSRHSGSRHHEASTHADIS----RHSQAVQGQSEGSR---RSRRQ 2887
Query: 351 NNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIR---------RILNTGLSETTSVA 401
++V+ +S+ G R + R + + + +R + G + +
Sbjct: 2888 GSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSS 2947
Query: 402 IQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSS--- 458
Q+ R T G + + + S + + + A+S S G G G +S +
Sbjct: 2948 RQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS-SRHSGIGHGQASSAVRDS 3006
Query: 459 -----SSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGA 508
S S +S + S S + S+ G S S +SG SG+
Sbjct: 3007 GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGS 3061
Score = 44.7 bits (104), Expect = 3e-04
Identities = 117/522 (22%), Positives = 187/522 (35%), Gaps = 74/522 (14%)
Query: 58 ESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVS-NGDSIIDWLNSVRQTGNTTRSGQ 116
+S+ + Q G P +S +G V +G S ++ Q + G
Sbjct: 2448 DSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGH 2507
Query: 117 RGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQV 176
G++S +R + SGD GS++S + + ++ R+ Q Q
Sbjct: 2508 SGSRSASRQTRNDEQSGD-------------GSRHSGSRHHEASSRADSSGHSQVGQGQS 2554
Query: 177 ENPRSE----STSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPL 232
E PR+ S+ ++ S S+ +S ++ +R + S S +H + R S
Sbjct: 2555 EGPRTSRNWGSSFSQDSDSQGHSEDS---------ERWSGSASRNHHGSAQEQLRDGSR- 2604
Query: 233 HPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQIS--GPELLSRGLFAASG 290
HP S R+ H S+ + T+ SS + + Q S G S +A
Sbjct: 2605 HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2664
Query: 291 TRNASQGAGSSDTAA--SGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQ 348
+R++ G G + +A SG SG + E DS + Q
Sbjct: 2665 SRHSGIGHGQASSAVRDSGHRGYSGSQ------------ASDNEGHSEDSDTQSVSAHGQ 2712
Query: 349 TPNNTVTY-ESERGGFRRTFSRSERAGVRTY-VSTIRIPIRRILNTGLSETTSVAIQTML 406
++ ++ ES RG R+ S +G Y VST TG S
Sbjct: 2713 AGSHQQSHQESARG---RSGETSGHSGSFLYQVSTHEQSESSHGWTGPS----------- 2758
Query: 407 RQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGG---GSSSGSSSSSSS 463
T + S + S + S ++ R S RGG G S SS S S
Sbjct: 2759 ----TRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGS 2814
Query: 464 SSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGS-----SGARREGRHRAPV 518
S ++S S + SG S+ ++ E S +GS SGS S RH V
Sbjct: 2815 HHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAV 2874
Query: 519 TFDESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRS 560
GS S Q +++D D + E+ A R+
Sbjct: 2875 QGQSEGSR--RSRRQGSSVSQDSDSEGHSEDSERWSGSASRN 2914
Score = 44.7 bits (104), Expect = 3e-04
Identities = 95/435 (21%), Positives = 157/435 (36%), Gaps = 48/435 (11%)
Query: 93 SNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGD---------FRFSLEINV 143
S+G S ++ Q + GQ G++S +R SGD S ++
Sbjct: 2808 SSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADI 2867
Query: 144 NRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTEALTEVP 203
+R++ + ++E +RR G +V +S + + SE S SR+ S +
Sbjct: 2868 SRHSQAVQGQSEGSRRSRRQ-GSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLR-- 2924
Query: 204 PTRGQRRARSRSPD-----HRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNE 258
G R RS D H +R +R SH S E +
Sbjct: 2925 --DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHH 2982
Query: 259 TEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPT 318
+ + +RH Q S + G SG++ AS G S+ + + + GQ
Sbjct: 2983 QQSADSSRHSGIGHGQASSA-VRDSGHRGYSGSQ-ASDNEGHSEDSDTQSVSAHGQAGSH 3040
Query: 319 IVLDLQVRRVRPGEYRQRDS-----IASRTRSRSQTPNNTVTYESERGGFRRTFSRSERA 373
+ R R GE +++ +S S ++ T S RG R SR E+A
Sbjct: 3041 QQSHQESARGRSGETSGHSGSFLYQVSTHEQSES---SHGWTGPSTRG---RQGSRHEQA 3094
Query: 374 GVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVS 433
+ S + + T R G+ + +S S +GS
Sbjct: 3095 QDSSRHSASQY----------GQDTIRGHPGSSRGGRQGY----HHEHSVDSSGHSGSHH 3140
Query: 434 NRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLF 493
+ + S + RG SG S+S ++ + S SS S S +S+ S S
Sbjct: 3141 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRH--SQAV 3198
Query: 494 EGSNEGSSSSGSSGA 508
+G +EGS S G+
Sbjct: 3199 QGQSEGSRRSRRQGS 3213
Score = 43.9 bits (102), Expect = 4e-04
Identities = 106/490 (21%), Positives = 171/490 (34%), Gaps = 81/490 (16%)
Query: 77 PQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGD-- 134
P+ S S D S G S +S R++G+ +R+ Q +P S
Sbjct: 2233 PRTSRPRGSSVSQDSDSEGHSE----DSERRSGSASRNHHGSAQEQSRDGSRHPRSHHED 2288
Query: 135 -FRFSLEINVNRNNGSQNSENEN-------EPSARRSSGENVENNSQRQVENPRSE---- 182
+R +G+ ++EN + AR S+GE ++ Q+ ++ R
Sbjct: 2289 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 2348
Query: 183 --------------STSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHR---RTRARA 225
S+ ++ S SE +S ++ T+ GQ +S R+ R+
Sbjct: 2349 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 2408
Query: 226 ERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGL 285
RS S L+ +S +H S H + G + HH R
Sbjct: 2409 GRSGSFLYQVS-----THEQSESA---HGRTGTSTGGRQGSHHKQARDS----------- 2449
Query: 286 FAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYR-----QRDSIA 340
+R+++ G DT + SG R + L R G + Q S A
Sbjct: 2450 -----SRHSTSQEGQ-DTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDA 2503
Query: 341 SRTRSRSQTPNNTVTYESERG-GFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTS 399
S S S++ + + + G G R + SR A R S + G SE
Sbjct: 2504 SHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSG-----HSQVGQGQSEGPR 2558
Query: 400 VAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSS 459
+ R + F + S DSE ++RN + R GS S
Sbjct: 2559 TS-----RNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDR 2613
Query: 460 SSSSSSSSSSSSSSSSSPSSSSGGE--SSETSSDLFEGSNEGSSSSGSSGARRE---GRH 514
+ S+ SS S + +SSGG+ SS + G GS S+ + R G
Sbjct: 2614 AGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHG 2673
Query: 515 RAPVTFDESG 524
+A +SG
Sbjct: 2674 QASSAVRDSG 2683
Score = 43.1 bits (100), Expect = 8e-04
Identities = 111/498 (22%), Positives = 176/498 (35%), Gaps = 62/498 (12%)
Query: 81 DENRGGDSSDDVSNGDSIIDWLNSVR--QTGNTTRSGQRGNQ-SWRAVSRTNPNS--GDF 135
D+ G S S W +S R Q G SG R ++ +VS+ + + D
Sbjct: 1223 DKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDD 1282
Query: 136 RFSLEINVNRNNGSQNSENENEPSA--------RRSSGENVENNSQRQVENPRSES---- 183
L + +RN+ + E + S R S G + +++ Q + S S
Sbjct: 1283 SERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQA 1342
Query: 184 ----TSARPSRSERNSTEALTEVPPTR----GQRRARS--RSPDHRR------TRARAER 227
AR S ER+ + +R G R+A S R HR T +
Sbjct: 1343 VSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHS 1402
Query: 228 SRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRT-RHHVTLRQQI------SGPEL 280
S +S + H S + E+ G SR+ + V+ +Q + P
Sbjct: 1403 EDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPST 1462
Query: 281 LSRGLFAASGTRNASQGAGSSD---TAASGESTGSGQRPPTIVLDLQVRRVRPGEYR--- 334
R RN+S+ + S D T + G R + R G +
Sbjct: 1463 GGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHT 1522
Query: 335 --QRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNT 392
Q S AS +S ++ + E + G S +G R + + R R
Sbjct: 1523 TPQGRSDASHGQSGPRSASRQTRNEEQSG------DGSRHSGSRHHEPSTRAGSSRHSQV 1576
Query: 393 GLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGG 452
G E S +T RQ + + +S+ DSE ++RN + R GS
Sbjct: 1577 GQGE--SAGSKTSRRQGSSVSQDRDSEGHSE-DSERRSESASRNHYGSAREQSRHGSRNP 1633
Query: 453 SSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGE--SSETSSDLFEGSNEGS---SSSGSSG 507
S +S S+ SS S + +SSGG+ SS+ + G GS S+ SS
Sbjct: 1634 RSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSST 1693
Query: 508 ARREGRHRAPVTFDESGS 525
GR + +SG+
Sbjct: 1694 DSGTGRRQDSSVVGDSGN 1711
Score = 42.4 bits (98), Expect = 0.001
Identities = 96/460 (20%), Positives = 166/460 (36%), Gaps = 64/460 (13%)
Query: 78 QNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRF 137
++ N D S+G S S RQ+G G Q+ + + + G+
Sbjct: 1627 RHGSRNPRSHQEDRASHGHSA----ESSRQSGTRHAETSSGGQAASSQEQARSSPGE--- 1679
Query: 138 SLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARPSRSERNSTE 197
+GS++ ++ + + SG +S ++ S+ ++ S SE +S E
Sbjct: 1680 --------RHGSRHQQSADSST---DSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEE 1728
Query: 198 ALTEVPPTRGQRRARSRSPDHR---RTRARAERSRSPLHPMS--EIPRRSHHSISSQTFE 252
+ T+ GQ +S ++ R+ RS S L+ +S E +H T
Sbjct: 1729 SDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGG 1788
Query: 253 HPLVNETEGSSRTRHHVTLRQQ--ISGPELLSRGLFAASGTRNASQGAGSSDTAASGEST 310
+ +RH + Q I G SRG QG+ + S +
Sbjct: 1789 RQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRG---------GRQGSHYEQSVDSSGHS 1839
Query: 311 GSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERG-GFRRTFSR 369
GS T Q S SR +S S++ + E + G G R + SR
Sbjct: 1840 GSHHSHTT---------------SQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSR 1884
Query: 370 SERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPT 429
A R S ++ + + S +T Q + + +S+ +
Sbjct: 1885 HHEASSRADSSR---------HSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWS 1935
Query: 430 GSVSNRNMERAESRSGRGGSGGGS-----SSGSSSSSSSSSSSSSSSSSSSSPSSSSGGE 484
GS S ++ A +S G GS + S+ SS S + + SSS ++S E
Sbjct: 1936 GSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHE 1995
Query: 485 SSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESG 524
+ +S+ GS+ S+ SS G +A +SG
Sbjct: 1996 QARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSG 2035
Score = 42.4 bits (98), Expect = 0.001
Identities = 107/486 (22%), Positives = 179/486 (36%), Gaps = 67/486 (13%)
Query: 73 EGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTT-----RSGQRGNQSWRAVSR 127
EGP + + SD + + W S + + + R G R +S +
Sbjct: 2555 EGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRA 2614
Query: 128 TNPNSGDF-RFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSES--- 183
+ +S D R S + ++G Q + + + AR S+GE ++ Q+ ++ R
Sbjct: 2615 GHGHSADSSRQSGTRHTQTSSGGQAASSHEQ--ARSSAGERHGSHHQQSADSSRHSGIGH 2672
Query: 184 ---------------TSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERS 228
+ ++ S +E +S ++ T+ GQ A S H+ + AR
Sbjct: 2673 GQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQ--AGSHQQSHQES-ARGRSG 2729
Query: 229 RSPLHPMSEIPRRSHH--SISSQTFEHPLVNETEGSSRTRHHVTLRQQIS--GPELLSRG 284
+ H S + + S H S SS + P +GS + + R S G + + RG
Sbjct: 2730 ETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTI-RG 2788
Query: 285 LFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTR 344
+S R QG + S +GS T Q S ASR +
Sbjct: 2789 HPGSS--RGGRQGYHHEHSVDSSGHSGSHHSHTT---------------SQGRSDASRGQ 2831
Query: 345 SRSQTPNNTVTYESERG-GFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQ 403
S S++ + T E + G G R + SR A +S ++ G SE + +
Sbjct: 2832 SGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQ-----GQSEGSRRS-- 2884
Query: 404 TMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSS 463
R+ + + S DSE ++RN + R GS S +
Sbjct: 2885 ---RRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHG 2941
Query: 464 SSSSSSSSSSSSSPSSSSGGE--SSETSSDLFEGSNEGSSSSGSSGARRE---GRHRAPV 518
S+ SS S + +SSGG+ SS + G GS S+ + R G +A
Sbjct: 2942 HSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS 3001
Query: 519 TFDESG 524
+SG
Sbjct: 3002 AVRDSG 3007
Score = 42.4 bits (98), Expect = 0.001
Identities = 108/513 (21%), Positives = 179/513 (34%), Gaps = 90/513 (17%)
Query: 59 STEEELLRRLQQIK---EGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQT--GNTTR 113
ST ++ R Q ++ EG + SD + + W S + G+
Sbjct: 3186 STHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE 3245
Query: 114 SGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENEN-------EPSARRSSGE 166
+ G++ R+ G + +R +G++++E + AR S GE
Sbjct: 3246 QSRHGSRHPRSHHEDRAGHGH-----SADRSRQSGTRHAETSSGGQAASSHEQARSSPGE 3300
Query: 167 NVENNSQRQVEN------PRSESTSA------------RPSRSERNSTEALTEVPPTRGQ 208
+ Q+ ++ PR +++SA + S SE +S E+ T+ GQ
Sbjct: 3301 RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQ 3360
Query: 209 RRARSRSPDHR---RTRARAERSRSPLHPMS--EIPRRSHHSISSQTFEHPLVNETEGSS 263
+S R+ R+ RS S L+ +S E +H + T + +
Sbjct: 3361 AGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARD 3420
Query: 264 RTRHHVTLRQQ--ISG-PELLSRGL----FAASGTRNASQGAGSSDTAASGESTGSGQRP 316
+RH + Q I G P RG + S R+ G+ S T + G S S
Sbjct: 3421 SSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDAS---- 3476
Query: 317 PTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVR 376
R SR+ SR QT N+ E G R ++S A +
Sbjct: 3477 -------------------RGQSGSRSASR-QTRND----EQSGDGSRHSWSHHHEASTQ 3512
Query: 377 TYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRN 436
S R +G ++ R + + S DSE ++RN
Sbjct: 3513 ADSS-------RHSQSGQGQSAGPRTS---RNQGSSVSQDSDSQGHSEDSERWSGSASRN 3562
Query: 437 MERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGE--SSETSSDLFE 494
+ R GS +S + S+ SS S + +SSGG+ SS +
Sbjct: 3563 HRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSA 3622
Query: 495 GSNEGSSSSGSSGARRE---GRHRAPVTFDESG 524
G GS S+ + R G +A +SG
Sbjct: 3623 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 3655
Score = 40.8 bits (94), Expect = 0.004
Identities = 101/470 (21%), Positives = 153/470 (32%), Gaps = 112/470 (23%)
Query: 78 QNSDEN-RGGDSSDDVS--------NGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRT 128
+N EN R GD+ +S N + + D+ N+ R T +SG
Sbjct: 185 KNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATY-------- 236
Query: 129 NPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTSARP 188
++++ S EN+ +R S G+ S QV R E+TS P
Sbjct: 237 --------YTIQDEAYDTTDSLLEENKIYERSRSSDGK-----SSSQVNRSRHENTSQVP 283
Query: 189 SRSERNSTEALTEVPPTR--------GQRRARSRSPDHRRTRARAERSRSPLHPMSEIPR 240
+ R + V R +R + S S +H + R S HP S
Sbjct: 284 LQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSR-HPRSHDED 342
Query: 241 RSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS 300
R+ H S+ + E SSR + + Q S P G R+ S S
Sbjct: 343 RASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSP-----------GERHGSGHQQS 391
Query: 301 SDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESER 360
+D++ +TG GQ + G S AS + S+ + +
Sbjct: 392 ADSSRHS-ATGRGQASSAVS--------DRGHRGSSGSQASDSEGHSENSDTQSVSGHGK 442
Query: 361 GGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFM 420
G R+ +S + R G S S + L Q+ T
Sbjct: 443 AGLRQ---QSHQESTR----------------GRSGERSGRSGSSLYQVSTH-------- 475
Query: 421 YSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSS---- 476
E+ +S GR G+ G GS + SS S+S
Sbjct: 476 -----------------EQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRG 518
Query: 477 -PSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGS 525
P SS GG E S S SGS + + R+ + +SGS
Sbjct: 519 HPGSSRGGRQGSHH----EQSVNRSGHSGSHHSHTTSQGRSDASHGQSGS 564
Score = 37.0 bits (84), Expect = 0.054
Identities = 104/482 (21%), Positives = 166/482 (34%), Gaps = 72/482 (14%)
Query: 57 GESTEEELLRRLQQIKEGPP-PQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSG 115
G ++ L +Q ++G P + E+R G S+ S R T +++R G
Sbjct: 1936 GSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQS------GTRHTESSSR-G 1988
Query: 116 QRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQ 175
Q + +A S G + +R++G + + SA R SG + SQ
Sbjct: 1989 QAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQAS---SAVRDSGHRGYSGSQ-- 2043
Query: 176 VENPRSESTSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPM 235
S SE + T++++ Q +A H+ + AR + S
Sbjct: 2044 --------ASDSEGHSEDSDTQSVS------AQGKAGPHQQSHKES-ARGQSGESSGRSG 2088
Query: 236 SEIPRRSHHSISSQTFEH--PLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASG--- 290
S + + S H S T P +GS H Q S G G
Sbjct: 2089 SFLYQVSTHEQSESTHGQSAPSTGGRQGS-----HYDQAQDSSRHSASQEGQDTIRGHPG 2143
Query: 291 -TRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQT 349
+R QG+ + +GS T Q S ASR +S S++
Sbjct: 2144 PSRGGRQGSHQEQSVDRSGHSGSHHSHTT---------------SQGRSDASRGQSGSRS 2188
Query: 350 PNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSE--TTSVAIQTMLR 407
+ TY+ E+ G S S ++ + R ++ G S TS + +
Sbjct: 2189 ASRK-TYDKEQSGDGSRHSGSHHHEASSWADSSR---HSLVGQGQSSGPRTSRPRGSSVS 2244
Query: 408 QIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSS 467
Q G DSE ++RN + R GS S + S+
Sbjct: 2245 QDSDSEGH-------SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAE 2297
Query: 468 SSSSSSSSSPSSSSGGE--SSETSSDLFEGSNEGSSSSGSSGARRE---GRHRAPVTFDE 522
SS S + +SSGG+ SS + G GS S+ + R G +A +
Sbjct: 2298 SSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRD 2357
Query: 523 SG 524
SG
Sbjct: 2358 SG 2359
Score = 32.0 bits (71), Expect = 1.8
Identities = 96/496 (19%), Positives = 165/496 (33%), Gaps = 59/496 (11%)
Query: 74 GPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSG 133
GP + + SD + + W S + + Q + S S +G
Sbjct: 3528 GPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAG 3587
Query: 134 DFRFSLEINVNRNNGSQNSENEN-------EPSARRSSGENVENNSQRQVENPRSE---- 182
+ +R +G+ ++EN + AR S+GE ++ Q+ ++ R
Sbjct: 3588 HGHSA---ESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 3644
Query: 183 --------------STSARPSRSERNSTEALTEVPPTRGQRRARSRSPDHR---RTRARA 225
S+ ++ S SE +S ++ T+ GQ +S R+ R+
Sbjct: 3645 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 3704
Query: 226 ERSRSPLHPMS--EIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQ--ISGPELL 281
RS S L+ +S E +H T + +RH + Q I G
Sbjct: 3705 GRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGS 3764
Query: 282 SRG-----LFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQR 336
RG S R+ G+ S T + G S S + + + R R
Sbjct: 3765 RRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSR 3824
Query: 337 DSIASRTRSRSQTPNN--TVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGL 394
S + + +Q ++ + + + E G RR SR + + V + P +
Sbjct: 3825 HSGSRHHEASTQADSSRHSQSGQGESAGSRR--SRRQGSSVSQDSDSEAYPED---SERR 3879
Query: 395 SETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSS 454
SE+ S R+ S S GS +S + S
Sbjct: 3880 SESASRNHHGSSRE------------QSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKE 3927
Query: 455 SGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRH 514
G SS S S+ S S SP SSS ++ +G + GS G+
Sbjct: 3928 HGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYG 3987
Query: 515 RAPVTFDESGSLPFLS 530
+ + GS+ + S
Sbjct: 3988 ESGFRHSQHGSVSYNS 4003
>gi|29788758 ring finger protein 130 [Homo sapiens]
Length = 419
Score = 62.8 bits (151), Expect = 9e-10
Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 7/100 (7%)
Query: 523 SGSLPFLSLAQFFLLNEDDDDQPR--GLTKEQIDNLAMRSFGENDA-----LKTCSVCIT 575
S L F + + N D +Q R K+ I L R+ + D C+VCI
Sbjct: 210 SAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIE 269
Query: 576 EYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVL 615
Y + + +R LPC H +H C+D WLSE+ TCP+C+ +L
Sbjct: 270 SYKQNDVVRILPCKHVFHKSCVDPWLSEHCTCPMCKLNIL 309
>gi|150378447 zinc and ring finger 3 [Homo sapiens]
Length = 836
Score = 62.4 bits (150), Expect = 1e-09
Identities = 21/55 (38%), Positives = 35/55 (63%)
Query: 570 CSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESVV 624
C++C+ +Y +G +LR +PC+H +H C+D WL ++ TCP CR ++ S V
Sbjct: 193 CAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAV 247
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 61.2 bits (147), Expect = 3e-09
Identities = 103/458 (22%), Positives = 177/458 (38%), Gaps = 59/458 (12%)
Query: 66 RRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAV 125
RR + K GPP + +++S+ S D + +RQ G T + + V
Sbjct: 89 RRSGRDKYGPPTRTEYRL----IVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGV 144
Query: 126 SRTNPNSGDFRFSLEINVNRNNGSQNSENENEPSARRSSGENVENNSQRQVENPRSESTS 185
S R +++ NG + E++P +RR + + R RS S
Sbjct: 145 IEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRS----RSRSRH 200
Query: 186 ARPSRSERNSTEALTEVPPTRGQR----RARSRSPDHRRTRARAERSRSPLHPMSEIPRR 241
+R SRS S+++ +R + R++SRS R+R++ E+SRSP S R
Sbjct: 201 SRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSR--SR 258
Query: 242 SHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQG---A 298
SH + G SR++ ++I + + + + S +R+ S+ +
Sbjct: 259 SH---------------SAGKSRSKSKDQAEEKIQNNDNVGKPK-SRSPSRHKSKSKSRS 302
Query: 299 GSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYES 358
S + E GS R + Q + +R R R SR+RSRS++ + +
Sbjct: 303 RSQERRVEEEKRGSVSRGRS-----QEKSLRQSRSRSRSKGGSRSRSRSRSKS-----KD 352
Query: 359 ERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSY 418
+R G +R+ S S R R G + ++ T
Sbjct: 353 KRKGRKRSREESRSR------SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD------ 400
Query: 419 FMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPS 478
P+ SVS + E A+S S + G S + ++ + S S S+S S + PS
Sbjct: 401 ---RSQSRSPSRSVS-KEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPS 456
Query: 479 SSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRA 516
S S + + S S+S S +R R+
Sbjct: 457 ESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 54.3 bits (129), Expect = 3e-07
Identities = 78/333 (23%), Positives = 132/333 (39%), Gaps = 33/333 (9%)
Query: 56 PGESTEEELLRRLQQIKEGPPPQNSDENRGGDSSDDVSNGDSIIDWLNSVRQTGNTTRSG 115
PG R + ++S ++R S S+ S S ++G+ +RS
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKS-----RSRSRSGSRSRSK 231
Query: 116 QRGNQSWRAVSRTNPNSGDFRFSLEINVNRNN--GSQNSENENEPSARRSSGENVENNSQ 173
R R+ S+ + S E + +R++ G S+++++ + + +NV
Sbjct: 232 SRSRSQSRSRSKKEKSRSP---SKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS 288
Query: 174 RQVENPRSESTSARPSRSERNSTEALTEVPPTRGQR------RARSRSPDHRRTRARAE- 226
R +S+S S S+ R E V R Q R+RSRS R+R+R+
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348
Query: 227 --------RSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGP 278
R RS S RS S S+ ++ S + + T R Q P
Sbjct: 349 KSKDKRKGRKRSREESRSRSRSRS-KSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 279 -ELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRD 337
+S+ A + +G G S+ A + + T S R + + + P E R R
Sbjct: 408 SRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRS-----NSKSKPNLPSESRSRS 462
Query: 338 SIASRTRSRSQTPNNTVTYESERGGFRRTFSRS 370
AS+TRSRS++ + + + R R+ SRS
Sbjct: 463 KSASKTRSRSKSRSRSASRSPSRSR-SRSHSRS 494
Score = 48.9 bits (115), Expect = 1e-05
Identities = 77/333 (23%), Positives = 121/333 (36%), Gaps = 53/333 (15%)
Query: 199 LTEVPPTRGQRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNE 258
L E P +RR+ SRS H R+R+R+ SR + S SS++ +
Sbjct: 172 LVEDKPGSRRRRSYSRSRSHSRSRSRSRHSR----------KSRSRSGSSKSSHSKSRSR 221
Query: 259 TEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPT 318
+ SR+R R Q SR +R+ S+ S + ++G+S +
Sbjct: 222 SRSGSRSRSKSRSRSQ-------SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAE 274
Query: 319 IVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTY 378
+ +P + R S+++SRS++ V E +RG R RS+ +R
Sbjct: 275 EKIQNNDNVGKP-KSRSPSRHKSKSKSRSRSQERRVE-EEKRGSVSR--GRSQEKSLRQS 330
Query: 379 VSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNRNME 438
S R + G S + S + S S + G +R
Sbjct: 331 RSRSR-------SKGGSRSRSRS-------------------RSKSKDKRKGRKRSREES 364
Query: 439 RAESRSG----RGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFE 494
R+ SRS R G + SS + S S SPS S E S+
Sbjct: 365 RSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSE--S 422
Query: 495 GSNEGSSSSGSSGARREGRHRAPVTFDESGSLP 527
EG S ++G +E R R+ +LP
Sbjct: 423 SQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
>gi|37595553 ring finger protein 111 [Homo sapiens]
Length = 986
Score = 61.2 bits (147), Expect = 3e-09
Identities = 25/60 (41%), Positives = 36/60 (60%)
Query: 563 ENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRES 622
E D + C++C++ EG +R+LPC H +H C+D+WL N CPICR + A ES
Sbjct: 927 EEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES 986
Score = 39.7 bits (91), Expect = 0.008
Identities = 85/393 (21%), Positives = 152/393 (38%), Gaps = 91/393 (23%)
Query: 144 NRNNGSQNSENENEPSARRSSGEN--VENNSQRQVE--------NPRSESTSARPSRSER 193
+ +N S S+ + PS+ G++ V ++ ++V N +S S SAR + R
Sbjct: 127 DEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPR 186
Query: 194 NSTEALTEV----PPTRGQ-------RRARSRSPDHRRTRARAERSRSPLHPMSEIPRRS 242
TE+++ + P G R+ ++ +RT+ + ER + RR
Sbjct: 187 TETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRK 246
Query: 243 HHSI--SSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGS 300
+ + SS + E+ L +E+ SS T L S + N + +GS
Sbjct: 247 YALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSAS-----------ENHQNNPAVPSGS 295
Query: 301 SDT------AASGESTGSGQRPPTIVLDLQVRRVRPGE-YRQRDSIASRTRSRSQTPNNT 353
D A+S + + D +V V GE YR R ++ SRS +
Sbjct: 296 IDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLG---HSRSHWSQGS 352
Query: 354 VTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGF 413
++ S R + R+ +ST+ P+R+ +E + +
Sbjct: 353 SSHAS----------RPQEPRNRSRISTVIQPLRQ----NAAEVVDLTVD---------- 388
Query: 414 GELSYFMYSDSDSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSS 473
+ EPT V R ES++ + +S ++S+ S+S +S +
Sbjct: 389 -----------EDEPT--VVPTTSARMESQA----------TSASINNSNPSTSEQASDT 425
Query: 474 SSSPSSSSGGESSETSSDLFEGSNEGSSSSGSS 506
+S+ +SS SETS+ L S G+S S
Sbjct: 426 ASAVTSSQPSTVSETSATLTSNSTTGTSIGDDS 458
>gi|58331204 ring finger protein 150 [Homo sapiens]
Length = 438
Score = 60.8 bits (146), Expect = 4e-09
Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 7/97 (7%)
Query: 526 LPFLSLAQFFLLNEDDDDQPR--GLTKEQIDNLAMRSFGENDA-----LKTCSVCITEYT 578
L F + +F N D +Q R K+ I L +R+ + D C+VCI Y
Sbjct: 227 LVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYK 286
Query: 579 EGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVL 615
+ +R LPC H +H C+D WL ++ TCP+C+ +L
Sbjct: 287 PNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNIL 323
>gi|56711322 ring finger protein 43 [Homo sapiens]
Length = 783
Score = 60.5 bits (145), Expect = 5e-09
Identities = 19/41 (46%), Positives = 32/41 (78%)
Query: 570 CSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPIC 610
C++C+ E++EG +LR + C HE+H +C+D WL ++ TCP+C
Sbjct: 272 CAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLC 312
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.123 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,930,366
Number of Sequences: 37866
Number of extensions: 1242595
Number of successful extensions: 37895
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 783
Number of HSP's successfully gapped in prelim test: 562
Number of HSP's that attempted gapping in prelim test: 15137
Number of HSP's gapped (non-prelim): 11217
length of query: 624
length of database: 18,247,518
effective HSP length: 108
effective length of query: 516
effective length of database: 14,157,990
effective search space: 7305522840
effective search space used: 7305522840
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.