Guide to the Human Genome
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Search of human proteins with 34452681

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34452681 ring finger protein 10 [Homo sapiens]
         (811 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34452681 ring finger protein 10 [Homo sapiens]                    1637   0.0  
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s...    50   8e-06
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s...    50   8e-06
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...    48   3e-05
gi|21071052 helicase-like transcription factor [Homo sapiens]          48   3e-05
gi|21071054 helicase-like transcription factor [Homo sapiens]          48   3e-05
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]     46   1e-04
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]     46   1e-04
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]     46   1e-04
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]       46   1e-04
gi|237858656 ring finger protein 170 isoform b [Homo sapiens]          45   3e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        45   3e-04
gi|237858658 ring finger protein 170 isoform c [Homo sapiens]          45   4e-04
gi|237858654 ring finger protein 170 isoform a [Homo sapiens]          45   4e-04
gi|237858650 ring finger protein 170 isoform a [Homo sapiens]          45   4e-04
gi|56605981 tripartite motif-containing 72 [Homo sapiens]              45   4e-04
gi|5902054 ring finger protein 5 [Homo sapiens]                        43   0.001
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    43   0.001
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         43   0.001
gi|209529681 ring finger protein 185 isoform 1 [Homo sapiens]          43   0.001
gi|31542783 ring finger protein 185 isoform 1 [Homo sapiens]           43   0.001
gi|24797089 peroxisome biogenesis factor 10 isoform 1 [Homo sapi...    42   0.002
gi|4505715 peroxisome biogenesis factor 10 isoform 2 [Homo sapiens]    42   0.002
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    42   0.002
gi|153791360 ret finger protein-like 4B [Homo sapiens]                 42   0.002
gi|121114298 cullin 4B isoform 1 [Homo sapiens]                        41   0.004
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    40   0.007
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    40   0.007
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    40   0.007
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         40   0.009

>gi|34452681 ring finger protein 10 [Homo sapiens]
          Length = 811

 Score = 1637 bits (4238), Expect = 0.0
 Identities = 811/811 (100%), Positives = 811/811 (100%)

Query: 1   MPLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGS 60
           MPLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGS
Sbjct: 1   MPLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGS 60

Query: 61  KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVA 120
           KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVA
Sbjct: 61  KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVA 120

Query: 121 EAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQTGHFEGSGHGSWGKRNKWGHKPFNKEL 180
           EAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQTGHFEGSGHGSWGKRNKWGHKPFNKEL
Sbjct: 121 EAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQTGHFEGSGHGSWGKRNKWGHKPFNKEL 180

Query: 181 FLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRC 240
           FLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRC
Sbjct: 181 FLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRC 240

Query: 241 GHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKRE 300
           GHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKRE
Sbjct: 241 GHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKRE 300

Query: 301 KGVLVALPKSKWMNVDHPIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEK 360
           KGVLVALPKSKWMNVDHPIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEK
Sbjct: 301 KGVLVALPKSKWMNVDHPIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEK 360

Query: 361 HTPESCFIEAAIQELKTREEALSGLAGSRREVTGVVAALEQLVLMAPLAKESVFQPRKGV 420
           HTPESCFIEAAIQELKTREEALSGLAGSRREVTGVVAALEQLVLMAPLAKESVFQPRKGV
Sbjct: 361 HTPESCFIEAAIQELKTREEALSGLAGSRREVTGVVAALEQLVLMAPLAKESVFQPRKGV 420

Query: 421 LEYLSAFDEETTEVCSLDTPSRPLALPLVEEEEAVSEPEPEGLPEACDDLELADDNLKEG 480
           LEYLSAFDEETTEVCSLDTPSRPLALPLVEEEEAVSEPEPEGLPEACDDLELADDNLKEG
Sbjct: 421 LEYLSAFDEETTEVCSLDTPSRPLALPLVEEEEAVSEPEPEGLPEACDDLELADDNLKEG 480

Query: 481 TICTESSQQEPITKSGFTRLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLERSPEK 540
           TICTESSQQEPITKSGFTRLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLERSPEK
Sbjct: 481 TICTESSQQEPITKSGFTRLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLERSPEK 540

Query: 541 ISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKR 600
           ISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKR
Sbjct: 541 ISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKR 600

Query: 601 KRQRQKKAREERRRERRIEIEENKKQGKYPEVHIPLENLQQFPAFNSYTCSSDSALGPTS 660
           KRQRQKKAREERRRERRIEIEENKKQGKYPEVHIPLENLQQFPAFNSYTCSSDSALGPTS
Sbjct: 601 KRQRQKKAREERRRERRIEIEENKKQGKYPEVHIPLENLQQFPAFNSYTCSSDSALGPTS 660

Query: 661 TEGHGALSISPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFPSFAQMLRVGK 720
           TEGHGALSISPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFPSFAQMLRVGK
Sbjct: 661 TEGHGALSISPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFPSFAQMLRVGK 720

Query: 721 AKADVWPKTAPKKDENSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPA 780
           AKADVWPKTAPKKDENSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPA
Sbjct: 721 AKADVWPKTAPKKDENSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPA 780

Query: 781 TSDPLSEEKGGKKRKKQKQKLLFSTSVVHTK 811
           TSDPLSEEKGGKKRKKQKQKLLFSTSVVHTK
Sbjct: 781 TSDPLSEEKGGKKRKKQKQKLLFSTSVVHTK 811


>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
           sapiens]
          Length = 326

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 61/260 (23%), Positives = 103/260 (39%), Gaps = 43/260 (16%)

Query: 221 EVPSCPICLYPPTAAKITRCGHIFCWACIL--HYLSLSEKTWSKCPICYSSVHKKDLKSV 278
           E  +CPICL   T      CGH FC AC+   H  S+ +K  S CP+C  S   ++++  
Sbjct: 11  EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIR-- 68

Query: 279 VATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHPIHLGD-------EQHSQYSK 331
                +++V      ++ +K            +   VDH    G+       E       
Sbjct: 69  ----PNRHVANIVEKLREVKL---------SPEGQKVDHCARHGEKLLLFCQEDGKVICW 115

Query: 332 LLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSGLAGSRRE 391
           L   S+E   H   L E+VA E Q+           ++AA++ L+ +++    L    RE
Sbjct: 116 LCERSQEHRGHHTFLTEEVAQEYQVK----------LQAALEMLRQKQQEAEELEADIRE 165

Query: 392 VTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEETTEVCSLDTPSRPLALPLVEE 451
                    Q      LA    F+  + +L++     EE+ E+ +L+     +   L   
Sbjct: 166 EKASWKTQIQYDKTNVLAD---FEQLRDILDW-----EESNELQNLEKEEEDILKSLTNS 217

Query: 452 EEAVSEPEPEGLPEACDDLE 471
           E  + + + + L E   DLE
Sbjct: 218 ETEMVQ-QTQSLRELISDLE 236


>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
           sapiens]
          Length = 347

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 61/260 (23%), Positives = 103/260 (39%), Gaps = 43/260 (16%)

Query: 221 EVPSCPICLYPPTAAKITRCGHIFCWACIL--HYLSLSEKTWSKCPICYSSVHKKDLKSV 278
           E  +CPICL   T      CGH FC AC+   H  S+ +K  S CP+C  S   ++++  
Sbjct: 11  EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIR-- 68

Query: 279 VATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHPIHLGD-------EQHSQYSK 331
                +++V      ++ +K            +   VDH    G+       E       
Sbjct: 69  ----PNRHVANIVEKLREVKL---------SPEGQKVDHCARHGEKLLLFCQEDGKVICW 115

Query: 332 LLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSGLAGSRRE 391
           L   S+E   H   L E+VA E Q+           ++AA++ L+ +++    L    RE
Sbjct: 116 LCERSQEHRGHHTFLTEEVAQEYQVK----------LQAALEMLRQKQQEAEELEADIRE 165

Query: 392 VTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEETTEVCSLDTPSRPLALPLVEE 451
                    Q      LA    F+  + +L++     EE+ E+ +L+     +   L   
Sbjct: 166 EKASWKTQIQYDKTNVLAD---FEQLRDILDW-----EESNELQNLEKEEEDILKSLTNS 217

Query: 452 EEAVSEPEPEGLPEACDDLE 471
           E  + + + + L E   DLE
Sbjct: 218 ETEMVQ-QTQSLRELISDLE 236


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 62/260 (23%), Positives = 106/260 (40%), Gaps = 43/260 (16%)

Query: 221 EVPSCPICLYPPTAAKITRCGHIFCWACIL--HYLSLSEKTWSKCPICYSSVHKKDLKSV 278
           E  +CPICL   T      CGH FC AC+   H  S+ +K  S CP+C  S   ++++  
Sbjct: 11  EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIR-- 68

Query: 279 VATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHPIHLGD-------EQHSQYSK 331
                +++V        L+++ + V ++    K   VDH    G+       E       
Sbjct: 69  ----PNRHVA------NLVEKLREVKLSPEGQK---VDHCARHGEKLLLFCQEDGKVICW 115

Query: 332 LLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSGLAGSRRE 391
           L   S+E   H     E+VA E Q+           ++AA++ L+ +++    L    RE
Sbjct: 116 LCERSQEHRGHHTFPTEEVAQEYQVK----------LQAALEMLRQKQQEAEELEADIRE 165

Query: 392 VTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEETTEVCSLDTPSRPLALPLVEE 451
                    Q      LA    F+  + +L++     EE+ E+ +L+     +   L   
Sbjct: 166 EKASWKTQIQYDKTNVLAD---FEQLRDILDW-----EESNELQNLEKEEEDILKSLTNS 217

Query: 452 EEAVSEPEPEGLPEACDDLE 471
           E  + + + + L E   DLE
Sbjct: 218 ETEMVQ-QTQSLRELISDLE 236


>gi|21071052 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%)

Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDL 275
           C ICL   T   IT C H+FC  CI   +  +E+  +KCP+C + +H+ +L
Sbjct: 760 CAICLDSLTVPVITHCAHVFCKPCICQVIQ-NEQPHAKCPLCRNDIHEDNL 809


>gi|21071054 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%)

Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDL 275
           C ICL   T   IT C H+FC  CI   +  +E+  +KCP+C + +H+ +L
Sbjct: 760 CAICLDSLTVPVITHCAHVFCKPCICQVIQ-NEQPHAKCPLCRNDIHEDNL 809


>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
          Length = 1884

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%)

Query: 212 VEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVH 271
           V+ V     ++  CPICL        T+C HIFC  C+L  L+  +K  S+CP+C + + 
Sbjct: 11  VQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLN-QKKGPSQCPLCKNDIT 69

Query: 272 KKDLK 276
           K+ L+
Sbjct: 70  KRSLQ 74


>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
          Length = 699

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%)

Query: 212 VEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVH 271
           V+ V     ++  CPICL        T+C HIFC  C+L  L+  +K  S+CP+C + + 
Sbjct: 11  VQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLN-QKKGPSQCPLCKNDIT 69

Query: 272 KKDLK 276
           K+ L+
Sbjct: 70  KRSLQ 74


>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
          Length = 759

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%)

Query: 212 VEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVH 271
           V+ V     ++  CPICL        T+C HIFC  C+L  L+  +K  S+CP+C + + 
Sbjct: 11  VQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLN-QKKGPSQCPLCKNDIT 69

Query: 272 KKDLK 276
           K+ L+
Sbjct: 70  KRSLQ 74


>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
          Length = 1863

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%)

Query: 212 VEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVH 271
           V+ V     ++  CPICL        T+C HIFC  C+L  L+  +K  S+CP+C + + 
Sbjct: 11  VQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLN-QKKGPSQCPLCKNDIT 69

Query: 272 KKDLK 276
           K+ L+
Sbjct: 70  KRSLQ 74


>gi|237858656 ring finger protein 170 isoform b [Homo sapiens]
          Length = 200

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)

Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTW---SKCPICYSSVHKKDLKSVVAT 281
           CPICL+  +    T CGH+FC ACI+ Y      +W     CPIC       +  S  + 
Sbjct: 87  CPICLHQASFPVETNCGHLFCGACIIAYWRYG--SWLGAISCPIC-RQTGSSEKSSRASE 143

Query: 282 ESHQYVV 288
           ++HQ  V
Sbjct: 144 QTHQEAV 150


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 3/114 (2%)

Query: 4    SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63
            SS ++++++S    +S S+SSS+SS SS     P  A  GP    KP S  K   G +R 
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRS 2675

Query: 64   NRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRD 117
               R+   P +   +++S   S  + +  +  P  R   SS     S  G R D
Sbjct: 2676 RSPRK---PIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGD 2726



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 3/109 (2%)

Query: 4    SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKS---DGKNSSGS 60
            SS ++++++S    +S  +SSS S GSS   QP  +    P+    PK    +G+    +
Sbjct: 2540 SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT 2599

Query: 61   KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSS 109
                ++R  S   + S ++ S  SSS  S + +         SS   SS
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 2/97 (2%)

Query: 2    PLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSK 61
            P + P  + + S   K  G +   +SS  S  + PP+S +A     S P+   K+ +  +
Sbjct: 1629 PRALPRRSRSGSS-SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR 1687

Query: 62   RYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQ 98
            R + +      +    + +S RS+S   +T ++ PP+
Sbjct: 1688 RRSSRSSPELTRKARLSRRS-RSASSSPETRSRTPPR 1723



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 14/106 (13%)

Query: 3   LSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKR 62
           LSSP + A +    + S S SS       K Q PPR + +G    S+PK+  +       
Sbjct: 762 LSSPRSKAKSRLSLRRSLSGSSPCPK--QKSQTPPRRSRSG---SSQPKAKSRTPP---- 812

Query: 63  YNRKRELSYP----KNESFNNQSRRSSSQKSKTFNKMPPQRGGGSS 104
             R R  S P    K+++ + QS  SSS   K  +  PP++G  +S
Sbjct: 813 -RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 7/107 (6%)

Query: 4    SSPNAAATASDMDKNSGSNSS------SASSGSSKGQQPPRSASAGPAGES-KPKSDGKN 56
            SSP   +      + S S SS      S SS   +    PR+ +    G S  PK  G  
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771

Query: 57   SSGSKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGS 103
             S S+    K   +  ++ S ++QS     Q+S++ +++  +R GGS
Sbjct: 1772 RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS 1818



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 37/142 (26%), Positives = 56/142 (39%), Gaps = 12/142 (8%)

Query: 8    AAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKR 67
            +A  A    K   S+SSS+SS SS       S+S+  +G S   S+G +         KR
Sbjct: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578

Query: 68   ELS---YPKN--------ESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRR 116
              S    PK         E    + +R SS  S + +         SS   SSS +    
Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638

Query: 117  DEVAEAQRAEFSPAQFSGPKKI 138
               + +  +  SPA+  GP+ +
Sbjct: 2639 SSSSSSSSSSPSPAK-PGPQAL 2659



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 23  SSSASSGSSKGQQPPRSASAGPAGESK-PKSDGKNSSGSKRYNRKRELSYPKNESFNNQS 81
           SSS+ S + K ++  +    G   ES  P+ + K SS  K++  + E    K+ S   +S
Sbjct: 177 SSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKS 236

Query: 82  RRSSSQKSK 90
           +R S  K +
Sbjct: 237 KRKSKDKKR 245



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 14/144 (9%)

Query: 5   SPNAAATASDMDKNSGSNSSSASSGSSKGQQPP---RSASAGPA--GESKPKSDGKNSSG 59
           SP     +   +      S SA  G S  + P    RS S  PA  G S+ ++  +  S 
Sbjct: 536 SPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSR 595

Query: 60  SKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKM-------PPQRGGGSSKLFSSSFN 112
           S+   R+R  S        ++SR  + ++S+T + +        P R  G S+  + +  
Sbjct: 596 SRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR 655

Query: 113 GGRRDE--VAEAQRAEFSPAQFSG 134
           G  R        +    +PA+ SG
Sbjct: 656 GRSRSRTPARRGRSRSRTPARRSG 679


>gi|237858658 ring finger protein 170 isoform c [Homo sapiens]
          Length = 174

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 5/49 (10%)

Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTW---SKCPICYSSV 270
           CPICL+  +    T CGH+FC ACI+ Y      +W     CPIC  +V
Sbjct: 3   CPICLHQASFPVETNCGHLFCGACIIAYWRYG--SWLGAISCPICRQTV 49


>gi|237858654 ring finger protein 170 isoform a [Homo sapiens]
          Length = 258

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 5/49 (10%)

Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTW---SKCPICYSSV 270
           CPICL+  +    T CGH+FC ACI+ Y      +W     CPIC  +V
Sbjct: 87  CPICLHQASFPVETNCGHLFCGACIIAYWRYG--SWLGAISCPICRQTV 133


>gi|237858650 ring finger protein 170 isoform a [Homo sapiens]
          Length = 258

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 5/49 (10%)

Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTW---SKCPICYSSV 270
           CPICL+  +    T CGH+FC ACI+ Y      +W     CPIC  +V
Sbjct: 87  CPICLHQASFPVETNCGHLFCGACIIAYWRYG--SWLGAISCPICRQTV 133


>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 59/267 (22%), Positives = 104/267 (38%), Gaps = 38/267 (14%)

Query: 220 HEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWS-KCPICYSSVHKKDLKS- 277
           H+  SCP+CL    A     CGH FC AC+           +  CP C +    + L + 
Sbjct: 9   HQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTN 68

Query: 278 ----------VVATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHPIHLGDEQHS 327
                         + H     D +++   ++++ ++  +  S   +  H +    E H+
Sbjct: 69  LQLARLVEGLAQVPQGHCEEHLDPLSI-YCEQDRALVCGVCASLGSHRGHRLLPAAEAHA 127

Query: 328 QYSKLLLASKEQVLHRVVLEEK--VALEQQLAEEKHTPES-------------CFIEAAI 372
           +    L   K Q+    + +EK    LE QL E + T                 F+ A  
Sbjct: 128 RLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALE 187

Query: 373 QELKTREEALSGLAG--SRREVTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEE 430
             L    E + G AG   RRE+  + + LEQL  M  + +E   +P+    E+L  +   
Sbjct: 188 GSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQ---TEFLMKYCLV 244

Query: 431 TTEVCSLDTPSRP-----LALPLVEEE 452
           T+ +  +   S P     + LP++ ++
Sbjct: 245 TSRLQKILAESPPPARLDIQLPIISDD 271


>gi|5902054 ring finger protein 5 [Homo sapiens]
          Length = 180

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)

Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKK 273
           C ICL     A ++ CGH++CW C+  +L    +   +CP+C + + ++
Sbjct: 27  CNICLETAREAVVSVCGHLYCWPCLHQWLETRPER-QECPVCKAGISRE 74


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 24/148 (16%)

Query: 13  SDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSYP 72
           SD +  SG   S+ S   S+ +   +S+S   +GES  +SD ++    +   R  E    
Sbjct: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSE---- 734

Query: 73  KNESFNNQSRRSSSQKSKTFNKMPPQRGGGSS--KLFSSSFNGGRRDEVAEAQRAEFSPA 130
                + QS     +K+K   K+P ++G  SS  +   SS +    +  +E++  +  PA
Sbjct: 735 -----SEQSEEDGKRKTK--KKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPA 787

Query: 131 QFS-----------GPKKINLNHLLNFT 147
            +S             K+I+L  L +FT
Sbjct: 788 SWSRKTPPSSKSAPATKEISLLDLEDFT 815


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 10/121 (8%)

Query: 4   SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63
           SS ++++++S    +SGS+SSS SS S        S+S+  +G S   S    SS S+  
Sbjct: 577 SSSSSSSSSSSTSSSSGSSSSSGSSSSRSSS----SSSSSTSGSSSRDSSSSTSSSSESR 632

Query: 64  NRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAEAQ 123
           +R R     +  + + + RRS  +K +  + +  +R   SSK  SS    G +D+ + + 
Sbjct: 633 SRSR----GRGHNRDRKHRRSVDRKRRDTSGL--ERSHKSSKGGSSRDTKGSKDKNSRSD 686

Query: 124 R 124
           R
Sbjct: 687 R 687



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 29/123 (23%), Positives = 57/123 (46%), Gaps = 5/123 (4%)

Query: 4   SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63
           SS + ++++S    +  S+SSS+S+  S  +    S+S   + ES+ +S G+  +  +++
Sbjct: 589 SSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRD--SSSSTSSSSESRSRSRGRGHNRDRKH 646

Query: 64  NRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGS--SKLFSSSFNGGRRDEVAE 121
            R  +    ++ S   +S +SS   S    K    +   S   +  S S   G+R   +E
Sbjct: 647 RRSVDRK-RRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSE 705

Query: 122 AQR 124
             R
Sbjct: 706 RDR 708



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 13/89 (14%)

Query: 17  KNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSYPKNES 76
           +N  S S S SS SS       S+S+G +  S   S   +SS S             + +
Sbjct: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS-------------SST 613

Query: 77  FNNQSRRSSSQKSKTFNKMPPQRGGGSSK 105
             + SR SSS  S +       RG G ++
Sbjct: 614 SGSSSRDSSSSTSSSSESRSRSRGRGHNR 642


>gi|209529681 ring finger protein 185 isoform 1 [Homo sapiens]
          Length = 192

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHK 272
           C ICL     A I+ CGH+FCW C+  +L  +      CP+C + + +
Sbjct: 39  CNICLDTAKDAVISLCGHLFCWPCLHQWLE-TRPNRQVCPVCKAGISR 85


>gi|31542783 ring finger protein 185 isoform 1 [Homo sapiens]
          Length = 192

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)

Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHK 272
           C ICL     A I+ CGH+FCW C+  +L  +      CP+C + + +
Sbjct: 39  CNICLDTAKDAVISLCGHLFCWPCLHQWLE-TRPNRQVCPVCKAGISR 85


>gi|24797089 peroxisome biogenesis factor 10 isoform 1 [Homo
           sapiens]
          Length = 346

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 4/44 (9%)

Query: 223 PSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPIC 266
           P C +CL        T CGH+FCW CI  + S    + ++CP+C
Sbjct: 291 PLCTLCLEERRHPTATPCGHLFCWECITAWCS----SKAECPLC 330


>gi|4505715 peroxisome biogenesis factor 10 isoform 2 [Homo sapiens]
          Length = 326

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 4/44 (9%)

Query: 223 PSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPIC 266
           P C +CL        T CGH+FCW CI  + S    + ++CP+C
Sbjct: 271 PLCTLCLEERRHPTATPCGHLFCWECITAWCS----SKAECPLC 310


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 38/140 (27%), Positives = 55/140 (39%), Gaps = 11/140 (7%)

Query: 5    SPNAAATASDMDKNSGSNSS----------SASSGSSKGQQPPRSASAGPAGESKPKSDG 54
            S N++ ++   D N  SNSS          S SS SS       S+++  + ES   SD 
Sbjct: 873  SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932

Query: 55   KNSSGSKRYNRKRELSYPKNES-FNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNG 113
             NSS S   +   + S   N S  +N S  S+S  S   N         SS    SS + 
Sbjct: 933  SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992

Query: 114  GRRDEVAEAQRAEFSPAQFS 133
               D    +  ++ S +  S
Sbjct: 993  DSSDSSDSSNSSDSSDSSDS 1012



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 2/116 (1%)

Query: 4   SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63
           S+ + ++ +SD   +S S+SSS SS SS       S+++  + +S   SD  +S  S   
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719

Query: 64  NRKRELSYPKNESFNNQSRRS--SSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRD 117
           N     S   N S ++ S  S  SS  S + N         SS    SS +    D
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 35/114 (30%), Positives = 49/114 (42%), Gaps = 8/114 (7%)

Query: 4   SSPNAAATASDMDKNSGSNS-------SSASSGSSKGQQPPRSASAGPAGESKPKSDGKN 56
           SS ++ + +SD   +S SNS       SS SS SS       S+ +  + +S   SD  N
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 57  SSGSKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSS 110
           SS S   +   + S   N S +N S  +SS  S + N         SS    SS
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDS-SNSSDSSDSSNSSDSSNSSDSSDSSDSS 816



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 2/117 (1%)

Query: 4   SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSA--SAGPAGESKPKSDGKNSSGSK 61
           SS ++ ++ SD   +S S++SS SS SS       S+  S G   +S  +SD  NSS S 
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868

Query: 62  RYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDE 118
             +     S   + S +N+S  SS     + +         +S   S S N     E
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 2/121 (1%)

Query: 4    SSPNAAATASDMDKNSGSNS--SSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSK 61
            S  + ++ +SD D +  SNS  SS SS SS   +   S+    + +S   SD  +SS S 
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951

Query: 62   RYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAE 121
              +     S   N S ++ S  S S  S   +          S   S S N     + ++
Sbjct: 952  NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011

Query: 122  A 122
            +
Sbjct: 1012 S 1012



 Score = 37.4 bits (85), Expect = 0.056
 Identities = 30/130 (23%), Positives = 51/130 (39%), Gaps = 4/130 (3%)

Query: 4   SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63
           SS + ++ +SD D +  SNSS +S  S        S+ +  + +SK  S    S  S   
Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD----SSDSSDSSDSKSDSSKSESDSSDSD 637

Query: 64  NRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAEAQ 123
           ++        ++S +N     SS  S + +         SS    SS +    D    + 
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697

Query: 124 RAEFSPAQFS 133
            +E S +  S
Sbjct: 698 SSESSDSSDS 707



 Score = 37.0 bits (84), Expect = 0.073
 Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 5/107 (4%)

Query: 4   SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63
           S+ + ++ +SD   +  SNSS +S+ S        S+++  + +S   SDG +S  S R 
Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD----SSNSSDSSDSSDSSDGSDSDSSNRS 859

Query: 64  NRKREL-SYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSS 109
           +      S   ++S N+     SS  +++ N         SS   SS
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906



 Score = 37.0 bits (84), Expect = 0.073
 Identities = 22/86 (25%), Positives = 40/86 (46%)

Query: 4    SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63
            S  + ++ +SD   +S S+ SS SS SS       S  +  + +S   SD  NSS S   
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255

Query: 64   NRKRELSYPKNESFNNQSRRSSSQKS 89
            +   + +   N+  ++QS+  +   +
Sbjct: 1256 SDSSDSTSDSNDESDSQSKSGNGNNN 1281



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 30/133 (22%), Positives = 51/133 (38%), Gaps = 4/133 (3%)

Query: 5   SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGES----KPKSDGKNSSGS 60
           S    + +SD D +  SNSS +S  S        S+S   + +S       SD  +SS S
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601

Query: 61  KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVA 120
              +   + S   + S ++ S+  SS+     +    +     S    SS N    D   
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661

Query: 121 EAQRAEFSPAQFS 133
            +  ++ S +  S
Sbjct: 662 SSNSSDSSDSSDS 674



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 2/115 (1%)

Query: 5   SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYN 64
           S +++ ++   D +  S+SS +S  S       +S S     +SK  S   NSS S   +
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654

Query: 65  RKRELSYPKNESFNNQSRRS--SSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRD 117
              + S   N S ++ S  S  SS  S + N         SS    SS +    D
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 25/113 (22%), Positives = 46/113 (40%), Gaps = 4/113 (3%)

Query: 5   SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYN 64
           S +++ +++  D N  SNSS +S  S+       S+++  + +S   SD  +S+ S   N
Sbjct: 773 SSDSSDSSNSSDSNDSSNSSDSSDSSNSSD----SSNSSDSSDSSDSSDSDSSNSSDSSN 828

Query: 65  RKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRD 117
                    +   ++ S  S    S + N+        SS    SS +    D
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSD 881



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 24/106 (22%), Positives = 41/106 (38%), Gaps = 3/106 (2%)

Query: 5   SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYN 64
           S N +++  D   NS  +  + +   SKG +   S S      S    +G N +     N
Sbjct: 481 SDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDD---N 537

Query: 65  RKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSS 110
            K +    K++S ++ S  SS+    + +         SS    SS
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583


>gi|153791360 ret finger protein-like 4B [Homo sapiens]
          Length = 263

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 6/72 (8%)

Query: 224 SCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATES 283
           SCP+CL   + +    C H+FC+ CI  Y+  +    + CP+C      +D+  V A E 
Sbjct: 10  SCPVCLDFFSCSISLSCTHVFCFDCIQRYILENHDFRAMCPLC------RDVVKVPALEE 63

Query: 284 HQYVVGDTITMQ 295
            Q  V   +T Q
Sbjct: 64  WQVSVLTLMTKQ 75


>gi|121114298 cullin 4B isoform 1 [Homo sapiens]
          Length = 913

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 3/100 (3%)

Query: 15  MDKNSGS---NSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSY 71
           M ++SGS   N   A++    G   P  ++A  A E +  +DG  S+      +KR+L+ 
Sbjct: 2   MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61

Query: 72  PKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSF 111
             + S N+ + R     + + +  PP +   S+   +SSF
Sbjct: 62  SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSF 101



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 1/74 (1%)

Query: 5   SPNAAATASDM-DKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63
           SP+AAA A ++     G+ S++  + + K +    S+S+  +   +   D  +SS S   
Sbjct: 28  SPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPP 87

Query: 64  NRKRELSYPKNESF 77
            + R+ + P   SF
Sbjct: 88  LQPRDSASPSTSSF 101


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 52/226 (23%), Positives = 82/226 (36%), Gaps = 28/226 (12%)

Query: 587 KETLEMFSDDIEKRKRQRQKKAREERRRERRIEIEENKKQ------------GKYPEVHI 634
           KE  E    + E      + +A+EE++ E + E    K++             K P    
Sbjct: 561 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 620

Query: 635 PLENLQQFPAFNSYTCSSDSALGPTSTEGHGALSISPLSRSPGSHADFLLTPLSPTASQG 694
           P+E   + P   S          P   +G      SP+ +SP         P SP   +G
Sbjct: 621 PVEEKGKSPVPKS----------PVEEKGK-----SPVPKSPVEEKGKSPVPKSPVEEKG 665

Query: 695 SPSFCVGSLEEDSPFPSFAQMLRVGKAKADVWPKTAPKKDENSLVPPAPVDSDGESDNSD 754
                   +EE +  P     +   K+KA+V  K   K++E   V  AP +   E     
Sbjct: 666 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV-GKGEQKEEEEKEVKEAPKEEKVEKKEEK 724

Query: 755 RVPVPSFQNSFSQAIEAAFMKLDTPATSDPLSEEKGGKKRKKQKQK 800
              VP  + + S   E A  ++ T   S  +  EK  K+  K  Q+
Sbjct: 725 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 770


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 52/226 (23%), Positives = 82/226 (36%), Gaps = 28/226 (12%)

Query: 587 KETLEMFSDDIEKRKRQRQKKAREERRRERRIEIEENKKQ------------GKYPEVHI 634
           KE  E    + E      + +A+EE++ E + E    K++             K P    
Sbjct: 185 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 244

Query: 635 PLENLQQFPAFNSYTCSSDSALGPTSTEGHGALSISPLSRSPGSHADFLLTPLSPTASQG 694
           P+E   + P   S          P   +G      SP+ +SP         P SP   +G
Sbjct: 245 PVEEKGKSPVPKS----------PVEEKGK-----SPVPKSPVEEKGKSPVPKSPVEEKG 289

Query: 695 SPSFCVGSLEEDSPFPSFAQMLRVGKAKADVWPKTAPKKDENSLVPPAPVDSDGESDNSD 754
                   +EE +  P     +   K+KA+V  K   K++E   V  AP +   E     
Sbjct: 290 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV-GKGEQKEEEEKEVKEAPKEEKVEKKEEK 348

Query: 755 RVPVPSFQNSFSQAIEAAFMKLDTPATSDPLSEEKGGKKRKKQKQK 800
              VP  + + S   E A  ++ T   S  +  EK  K+  K  Q+
Sbjct: 349 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 394


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 25/88 (28%), Positives = 49/88 (55%), Gaps = 1/88 (1%)

Query: 4   SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKP-KSDGKNSSGSKR 62
           SS ++++++S    +S S+SSS+SS SS       S+S+     SKP K   ++     +
Sbjct: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209

Query: 63  YNRKRELSYPKNESFNNQSRRSSSQKSK 90
            +R+ + ++ +    +N+S + SS+K K
Sbjct: 210 DSREHKSAFKEPSRDHNKSSKESSKKPK 237



 Score = 37.0 bits (84), Expect = 0.073
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 9/92 (9%)

Query: 6   PNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNR 65
           PN +   S    +S S+SSS+SS SS       S+S+  +  S   S   +SS S  +++
Sbjct: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSTSFSK 195

Query: 66  KRELSYPKNESFNNQSRRSSS---QKSKTFNK 94
             +L     E  +  SR   S   + S+  NK
Sbjct: 196 PHKLMKEHKEKPSKDSREHKSAFKEPSRDHNK 227


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 35/137 (25%), Positives = 56/137 (40%), Gaps = 10/137 (7%)

Query: 4    SSPNAAATASDMDKNSGSNSSSASSGSSKGQ----QPPRSASAGPAGESKPKSDGKNSSG 59
            SS + ++++S    +SGS +     G   G        R+ SA  +  + P S   +SS 
Sbjct: 2562 SSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSS 2621

Query: 60   SKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEV 119
            S   +     S   + S ++ S  SSS  S + +         SS   SSS +    DE 
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-----SSSSSSSSSSSSSSSTTDED 2676

Query: 120  AEAQRA-EFSPAQFSGP 135
            +      E +PA  +GP
Sbjct: 2677 SSCSSDDEAAPAPTAGP 2693



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 1/129 (0%)

Query: 5    SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYN 64
            SP+ A    D  + S S+SSS SSGSS       S+ +   GE +   +G    G+   N
Sbjct: 2543 SPDKAQAEQDGAEESESSSSS-SSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN 2601

Query: 65   RKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAEAQR 124
                 S   + + ++ S  SSS  S + +         SS   SSS +       + +  
Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661

Query: 125  AEFSPAQFS 133
            +  S +  S
Sbjct: 2662 SSSSSSSSS 2670


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,754,996
Number of Sequences: 37866
Number of extensions: 1749098
Number of successful extensions: 11427
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 180
Number of HSP's successfully gapped in prelim test: 286
Number of HSP's that attempted gapping in prelim test: 9314
Number of HSP's gapped (non-prelim): 2128
length of query: 811
length of database: 18,247,518
effective HSP length: 111
effective length of query: 700
effective length of database: 14,044,392
effective search space: 9831074400
effective search space used: 9831074400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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