Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 34419635
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
(643 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 1272 0.0
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 1064 0.0
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 1064 0.0
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 1039 0.0
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 1018 0.0
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 1012 0.0
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 787 0.0
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 766 0.0
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 568 e-162
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 319 6e-87
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 301 2e-81
gi|48928056 heat shock protein 70kDa family member 13 precursor ... 279 7e-75
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 269 7e-72
gi|42544159 heat shock 105kD [Homo sapiens] 267 2e-71
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 229 5e-60
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 229 5e-60
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 39 0.019
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 39 0.019
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 39 0.019
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 39 0.019
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 37 0.043
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 37 0.043
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 37 0.043
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 37 0.043
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 37 0.056
gi|38348298 ankyrin repeat domain 45 [Homo sapiens] 37 0.073
gi|148746195 trichohyalin [Homo sapiens] 36 0.13
gi|92859701 myosin VI [Homo sapiens] 36 0.13
gi|9910266 kinesin family member 15 [Homo sapiens] 36 0.13
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 36 0.13
>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
Length = 643
Score = 1272 bits (3292), Expect = 0.0
Identities = 643/643 (100%), Positives = 643/643 (100%)
Query: 1 MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQ 60
MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQ
Sbjct: 1 MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQ 60
Query: 61 AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEE 120
AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEE
Sbjct: 61 AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEE 120
Query: 121 ISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTA 180
ISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTA
Sbjct: 121 ISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTA 180
Query: 181 AAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLV 240
AAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLV
Sbjct: 181 AAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLV 240
Query: 241 NHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSIT 300
NHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSIT
Sbjct: 241 NHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSIT 300
Query: 301 RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKE 360
RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKE
Sbjct: 301 RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKE 360
Query: 361 LNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNA 420
LNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNA
Sbjct: 361 LNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNA 420
Query: 421 TIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF 480
TIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF
Sbjct: 421 TIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF 480
Query: 481 DIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAA 540
DIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAA
Sbjct: 481 DIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAA 540
Query: 541 KNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRE 600
KNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRE
Sbjct: 541 KNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRE 600
Query: 601 LEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD 643
LEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD
Sbjct: 601 LEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD 643
>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
Length = 641
Score = 1064 bits (2751), Expect = 0.0
Identities = 525/636 (82%), Positives = 584/636 (91%)
Query: 8 AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
A+GIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q ALNP N
Sbjct: 6 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQN 65
Query: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
TVFDAKRLIGRKF D VQSDMKHWPF+V+++G KPKV+V Y+GE K FYPEEISSMVL+
Sbjct: 66 TVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLT 125
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
KMKE AEAYLG PV +AVITVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAIAYGL
Sbjct: 126 KMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 185
Query: 188 DRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEF 247
DR G GERNVLIFDLGGGTFDVS+L+ID G+FEVKATAGDTHLGGEDFDNRLVNHF+EEF
Sbjct: 186 DRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEF 245
Query: 248 RRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEEL 307
+RKH KD+S NKRA+RRLRTACERAKRTLSSSTQA+LEIDSLFEG+DFYTSITRARFEEL
Sbjct: 246 KRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEEL 305
Query: 308 CSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINP 367
CSDLFRSTLEPVEKALRDAKLDKAQIHD+VLVGGSTRIPKVQKLLQDFFNG++LNKSINP
Sbjct: 306 CSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINP 365
Query: 368 DEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQT 427
DEAVAYGAAVQAA+LMGDK E VQDLLLLDVAPLSLGLETAGGVMT LI+RN+TIPTKQT
Sbjct: 366 DEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQT 425
Query: 428 QTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI 487
Q FTTYSDNQPGV IQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI
Sbjct: 426 QIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI 485
Query: 488 LSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAH 547
L+VTATD+STGKANKITITNDKGRLSKEE+ERMV EAE+YKAEDE QR+RV+AKN+LE++
Sbjct: 486 LNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESY 545
Query: 548 VFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRP 607
F++K ++++E L+ KI E D++K+ DKC+EV++WL+ N LAEK+E+EH+++ELEQ+C P
Sbjct: 546 AFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNP 605
Query: 608 IFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD 643
I S LY G G PG G Q +G +GP IEEVD
Sbjct: 606 IISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641
>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
Length = 641
Score = 1064 bits (2751), Expect = 0.0
Identities = 525/636 (82%), Positives = 584/636 (91%)
Query: 8 AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
A+GIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q ALNP N
Sbjct: 6 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQN 65
Query: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
TVFDAKRLIGRKF D VQSDMKHWPF+V+++G KPKV+V Y+GE K FYPEEISSMVL+
Sbjct: 66 TVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLT 125
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
KMKE AEAYLG PV +AVITVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAIAYGL
Sbjct: 126 KMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 185
Query: 188 DRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEF 247
DR G GERNVLIFDLGGGTFDVS+L+ID G+FEVKATAGDTHLGGEDFDNRLVNHF+EEF
Sbjct: 186 DRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEF 245
Query: 248 RRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEEL 307
+RKH KD+S NKRA+RRLRTACERAKRTLSSSTQA+LEIDSLFEG+DFYTSITRARFEEL
Sbjct: 246 KRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEEL 305
Query: 308 CSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINP 367
CSDLFRSTLEPVEKALRDAKLDKAQIHD+VLVGGSTRIPKVQKLLQDFFNG++LNKSINP
Sbjct: 306 CSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINP 365
Query: 368 DEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQT 427
DEAVAYGAAVQAA+LMGDK E VQDLLLLDVAPLSLGLETAGGVMT LI+RN+TIPTKQT
Sbjct: 366 DEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQT 425
Query: 428 QTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI 487
Q FTTYSDNQPGV IQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI
Sbjct: 426 QIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI 485
Query: 488 LSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAH 547
L+VTATD+STGKANKITITNDKGRLSKEE+ERMV EAE+YKAEDE QR+RV+AKN+LE++
Sbjct: 486 LNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESY 545
Query: 548 VFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRP 607
F++K ++++E L+ KI E D++K+ DKC+EV++WL+ N LAEK+E+EH+++ELEQ+C P
Sbjct: 546 AFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNP 605
Query: 608 IFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD 643
I S LY G G PG G Q +G +GP IEEVD
Sbjct: 606 IISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 641
>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
Length = 641
Score = 1039 bits (2687), Expect = 0.0
Identities = 511/643 (79%), Positives = 585/643 (90%), Gaps = 2/643 (0%)
Query: 1 MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQ 60
M + +A+GIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q
Sbjct: 1 MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ 60
Query: 61 AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEE 120
A+NP NTVFDAKRLIGRKF D VQ+DMK WPF+V++EGGKPKV V Y+GE+K FYPEE
Sbjct: 61 VAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEE 120
Query: 121 ISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTA 180
ISSMVL+K+KETAEA+LG PV +AVITVPAYFNDSQRQATKDAG IAGLNVLRIINEPTA
Sbjct: 121 ISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA 180
Query: 181 AAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLV 240
AAIAYGLD+ G GER+VLIFDLGGGTFDVS+L+ID G+FEVKATAGDTHLGGEDFDNRLV
Sbjct: 181 AAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 240
Query: 241 NHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSIT 300
+HF+EEF+RKH KD+S NKRA+RRLRTACERAKRTLSSSTQA LEIDSL+EG+DFYTSIT
Sbjct: 241 SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT 300
Query: 301 RARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKE 360
RARFEELC+DLFR TLEPVEKALRDAK+DKA+IHD+VLVGGSTRIPKVQ+LLQD+FNG++
Sbjct: 301 RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD 360
Query: 361 LNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNA 420
LNKSINPDEAVAYGAAVQAA+LMGDK EKVQDLLLLDVAPLSLGLETAGGVMT LI+RN+
Sbjct: 361 LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS 420
Query: 421 TIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTF 480
TIPTKQTQ FTTYSDNQPGV IQVYEGERAMTKDNNLLGRF+L+GIPPAPRGVPQIEVTF
Sbjct: 421 TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF 480
Query: 481 DIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAA 540
DIDANGIL+VTATD+STGK NKITITNDKGRLSKEE+ERMV +AE+YKAEDE QR+++AA
Sbjct: 481 DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA 540
Query: 541 KNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRE 600
KN+LE++ F++K + +E L+ KI E D+ K+ DKC E+L+WLE NQLAEK+E++H+++E
Sbjct: 541 KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE 600
Query: 601 LEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVD 643
LEQ+C PI ++LY G G +CGT G P+TGP IEEVD
Sbjct: 601 LEQMCNPIITKLYQGGCT--GPACGTGYVPGRPATGPTIEEVD 641
>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
Length = 646
Score = 1018 bits (2631), Expect = 0.0
Identities = 501/641 (78%), Positives = 578/641 (90%), Gaps = 5/641 (0%)
Query: 8 AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
AVGIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q A+NP N
Sbjct: 6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
Query: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
TVFDAKRLIGR+F D VQSDMKHWPF VV++ G+PKV+V Y+GE K+FYPEE+SSMVL+
Sbjct: 66 TVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
KMKE AEAYLG+ V +AV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAIAYGL
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
Query: 188 DRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEF 247
D++ ERNVLIFDLGGGTFDVS+L+I+ G+FEVK+TAGDTHLGGEDFDNR+VNHF+ EF
Sbjct: 186 DKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEF 245
Query: 248 RRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEEL 307
+RKH KD+S NKRA+RRLRTACERAKRTLSSSTQA++EIDSL+EG+DFYTSITRARFEEL
Sbjct: 246 KRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEEL 305
Query: 308 CSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINP 367
+DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNGKELNKSINP
Sbjct: 306 NADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINP 365
Query: 368 DEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQT 427
DEAVAYGAAVQAA+L GDK E VQDLLLLDV PLSLG+ETAGGVMT LI+RN TIPTKQT
Sbjct: 366 DEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQT 425
Query: 428 QTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGI 487
QTFTTYSDNQPGV IQVYEGERAMTKDNNLLG+FEL+GIPPAPRGVPQIEVTFDIDANGI
Sbjct: 426 QTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGI 485
Query: 488 LSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAH 547
L+V+A D+STGK NKITITNDKGRLSKE++ERMV EAE+YKAEDE QRD+V++KNSLE++
Sbjct: 486 LNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESY 545
Query: 548 VFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRP 607
F++K ++++E L+ KI +ED++K+ DKC E++ WL+ NQ AEKEE+EHQ++ELE++C P
Sbjct: 546 AFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNP 605
Query: 608 IFSRLY---GG--PGVPGGSSCGTQARQGDPSTGPIIEEVD 643
I ++LY GG G+PGG G G S+GP IEEVD
Sbjct: 606 IITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646
>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
Length = 639
Score = 1012 bits (2617), Expect = 0.0
Identities = 503/639 (78%), Positives = 574/639 (89%), Gaps = 9/639 (1%)
Query: 8 AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
A+GIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q A+NP N
Sbjct: 7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
Query: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
T+FDAKRLIGRKF D TVQSDMKHWPFRVVSEGGKPKV+V Y+GE KTF+PEEISSMVL+
Sbjct: 67 TIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLT 126
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
KMKE AEAYLG V AVITVPAYFNDSQRQATKDAG I GLNVLRIINEPTAAAIAYGL
Sbjct: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
Query: 188 DRRGA--GERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFME 245
D++G GE+NVLIFDLGGGTFDVS+L+I+ G+FEVK+TAGDTHLGGEDFDNR+V+H E
Sbjct: 187 DKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAE 246
Query: 246 EFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFE 305
EF+RKH KD+ NKRA+RRLRTACERAKRTLSSSTQA++EIDSL+EGVDFYTSITRARFE
Sbjct: 247 EFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFE 306
Query: 306 ELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSI 365
EL +DLFR TLEPVEKALRDAKLDK QI ++VLVGGSTRIPK+QKLLQDFFNGKELNKSI
Sbjct: 307 ELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 366
Query: 366 NPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTK 425
NPDEAVAYGAAVQAA+L+GDK E VQDLLLLDV PLSLG+ETAGGVMT LI+RN TIPTK
Sbjct: 367 NPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTK 426
Query: 426 QTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDAN 485
QTQTFTTYSDNQ V +QVYEGERAMTKDNNLLG+F+L+GIPPAPRGVPQIEVTFDIDAN
Sbjct: 427 QTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDAN 486
Query: 486 GILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLE 545
GIL+VTA D+STGK NKITITNDKGRLSK++++RMV EAE+YK+EDEA RDRVAAKN+LE
Sbjct: 487 GILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALE 546
Query: 546 AHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQIC 605
++ +++K ++++E LR KI E+D+ K+ DKC+EV+ WL+ NQ+AEK+EYEH+++ELE++C
Sbjct: 547 SYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVC 606
Query: 606 RPIFSRLY-GGPGVPGGSSCGTQARQGDPSTGPIIEEVD 643
PI S+LY GGPG GGS G G GP IEEVD
Sbjct: 607 NPIISKLYQGGPG--GGSGGGGSGASG----GPTIEEVD 639
>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
Length = 493
Score = 787 bits (2032), Expect = 0.0
Identities = 389/468 (83%), Positives = 433/468 (92%), Gaps = 1/468 (0%)
Query: 8 AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
AVGIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q A+NP N
Sbjct: 6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
Query: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
TVFDAKRLIGR+F D VQSDMKHWPF VV++ G+PKV+V Y+GE K+FYPEE+SSMVL+
Sbjct: 66 TVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
KMKE AEAYLG+ V +AV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAIAYGL
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
Query: 188 DRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEF 247
D++ ERNVLIFDLGGGTFDVS+L+I+ G+FEVK+TAGDTHLGGEDFDNR+VNHF+ EF
Sbjct: 186 DKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEF 245
Query: 248 RRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEEL 307
+RKH KD+S NKRA+RRLRTACERAKRTLSSSTQA++EIDSL+EG+DFYTSITRARFEEL
Sbjct: 246 KRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEEL 305
Query: 308 CSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINP 367
+DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNGKELNKSINP
Sbjct: 306 NADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINP 365
Query: 368 DEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQT 427
DEAVAYGAAVQAA+L GDK E VQDLLLLDV PLSLG+ETAGGVMT LI+RN TIPTKQT
Sbjct: 366 DEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQT 425
Query: 428 QTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPA-PRGVP 474
QTFTTYSDNQPGV IQVYEGERAMTKDNNLLG+FEL+G+P P G P
Sbjct: 426 QTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
Score = 29.6 bits (65), Expect = 9.0
Identities = 14/27 (51%), Positives = 16/27 (59%)
Query: 617 GVPGGSSCGTQARQGDPSTGPIIEEVD 643
G+PGG G G S+GP IEEVD
Sbjct: 467 GMPGGFPGGGAPPSGGASSGPTIEEVD 493
>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
Length = 654
Score = 766 bits (1977), Expect = 0.0
Identities = 387/614 (63%), Positives = 492/614 (80%), Gaps = 6/614 (0%)
Query: 9 VGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFT-DTERLVGDAAKSQAALNPHN 67
VGIDLGTTYSCVGVF+ GRVEI+ANDQGNR TPSYVAFT + ERL+GDAAK+Q NP N
Sbjct: 31 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90
Query: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRG-EDKTFYPEEISSMVL 126
TVFDAKRLIGR + D +VQ D+K PF+VV + KP ++V G + KTF PEEIS+MVL
Sbjct: 91 TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150
Query: 127 SKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYG 186
+KMKETAEAYLG+ V HAV+TVPAYFND+QRQATKDAG IAGLNV+RIINEPTAAAIAYG
Sbjct: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210
Query: 187 LDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEE 246
LD+R GE+N+L+FDLGGGTFDVS+L+ID GVFEV AT GDTHLGGEDFD R++ HF++
Sbjct: 211 LDKR-EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKL 269
Query: 247 FRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEE 306
+++K GKD+ + RA+++LR E+AKR LSS QA +EI+S +EG DF ++TRA+FEE
Sbjct: 270 YKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEE 329
Query: 307 LCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSIN 366
L DLFRST++PV+K L D+ L K+ I ++VLVGGSTRIPK+Q+L+++FFNGKE ++ IN
Sbjct: 330 LNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGIN 389
Query: 367 PDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQ 426
PDEAVAYGAAVQA VL GD + DL+LLDV PL+LG+ET GGVMT LI RN +PTK+
Sbjct: 390 PDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKK 447
Query: 427 TQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANG 486
+Q F+T SDNQP V I+VYEGER +TKDN+LLG F+L+GIPPAPRGVPQIEVTF+ID NG
Sbjct: 448 SQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNG 507
Query: 487 ILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEA 546
IL VTA D+ TG NKITITND+ RL+ EE+ERMV++AE++ ED+ ++R+ +N LE+
Sbjct: 508 ILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELES 567
Query: 547 HVFHVKGSL-QEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQIC 605
+ + +K + +E L K+ ED+ M+ E + WLE +Q A+ E+++ +K+ELE+I
Sbjct: 568 YAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIV 627
Query: 606 RPIFSRLYGGPGVP 619
+PI S+LYG G P
Sbjct: 628 QPIISKLYGSAGPP 641
>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
Length = 679
Score = 568 bits (1464), Expect = e-162
Identities = 317/639 (49%), Positives = 423/639 (66%), Gaps = 22/639 (3%)
Query: 2 QAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFT-DTERLVGDAAKSQ 60
+A + VGIDLGTT SCV V + + ++L N +G RTTPS VAFT D ERLVG AK Q
Sbjct: 49 EAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQ 108
Query: 61 AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVV-SEGGKPKVRVCYRGEDKTFYPE 119
A NP+NT + KRLIGR++ D VQ D+K+ PF++V + G V K + P
Sbjct: 109 AVTNPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPS 164
Query: 120 EISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPT 179
+I + VL KMKETAE YLG K+AVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPT
Sbjct: 165 QIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPT 224
Query: 180 AAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRL 239
AAA+AYGLD+ + ++ + ++DLGGGTFD+S+L I GVFEVK+T GDT LGGEDFD L
Sbjct: 225 AAALAYGLDK--SEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282
Query: 240 VNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVD----F 295
+ H ++EF+R+ G DL+ + AL+R+R A E+AK LSSS Q + + L
Sbjct: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342
Query: 296 YTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDF 355
+TRA+FE + +DL R T+ P +KA++DA++ K+ I +V+LVGG TR+PKVQ+ +QD
Sbjct: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402
Query: 356 FNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTL 415
F G+ +K++NPDEAVA GAA+Q VL GD V D+LLLDV PLSLG+ET GGV T L
Sbjct: 403 F-GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKL 457
Query: 416 IQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQ 475
I RN TIPTK++Q F+T +D Q V I+V +GER M DN LLG+F L GIPPAPRGVPQ
Sbjct: 458 INRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQ 517
Query: 476 IEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQR 535
IEVTFDIDANGI+ V+A D+ TG+ +I I G LSK+++E MV AE+Y ED ++
Sbjct: 518 IEVTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKK 576
Query: 536 DRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYE 595
+RV A N E + + ++E +D++P ++ K++++ ++ L E
Sbjct: 577 ERVEAVNMAEGIIHDTETKMEE--FKDQLPADECNKLKEEISKMRELLARKDSETGENIR 634
Query: 596 HQKRELEQICRPIFSRLYG--GPGVPGGSSCGTQARQGD 632
L+Q +F Y G S GT ++ D
Sbjct: 635 QAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKED 673
>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
Length = 509
Score = 319 bits (817), Expect = 6e-87
Identities = 180/504 (35%), Positives = 283/504 (56%), Gaps = 7/504 (1%)
Query: 8 AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
A+G+ LG T +CV V++ GR ++AND G+R TP+ VA+++ E +VG AAK N N
Sbjct: 3 AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62
Query: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
TV K+++GR +D Q + V+ + GK + + E K PE+++ ++ S
Sbjct: 63 TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
KMKETA + LG VITVP F + Q+ A +A AG NVLR+I+EP+AA +AYG+
Sbjct: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182
Query: 188 DRRG-AGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEE 246
+ G+ N+L+F LGG + +SV+ +++G++ V +T D ++GG F L + E
Sbjct: 183 GQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLASE 242
Query: 247 FRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEE 306
F+R D+ GN RA+ +L + E AK +LS+ A +DSL+EG DF +++RARFE
Sbjct: 243 FQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFEL 302
Query: 307 LCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSIN 366
LCS LF +E + L I+ VVL GGS+RIPK+Q+L++D F EL SI
Sbjct: 303 LCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSIP 362
Query: 367 PDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAP---LSLGLETAGGV-MTTLIQRNATI 422
PDE + GAA++A +L+G + V+D L+++ + L G++ +G T L +
Sbjct: 363 PDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTPL 422
Query: 423 PTKQTQTFTTYSDNQPGVFIQVYEGE-RAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFD 481
P ++ T + V +++YE + + K+ + L + G+ I
Sbjct: 423 PARRQHTLQA-PGSISSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVLT 481
Query: 482 IDANGILSVTATDRSTGKANKITI 505
+ +G L VT TD+ TGK I+I
Sbjct: 482 MKRDGSLHVTCTDQETGKCEAISI 505
>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
Length = 840
Score = 301 bits (770), Expect = 2e-81
Identities = 191/581 (32%), Positives = 310/581 (53%), Gaps = 27/581 (4%)
Query: 9 VGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNT 68
VGIDLG V V + G +E +AN+ +R TP+ ++F R +G AAKSQ N NT
Sbjct: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
Query: 69 VFDAKRLIGRKFADTTVQSDMKHWPFRVVS-EGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
V KR GR F+D V+++ + + +V G ++V Y E++ F E++++M+LS
Sbjct: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
K+KETAE+ L +PV V++VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+
Sbjct: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
Query: 188 DRRG-----AGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNH 242
++ RNV+ D+G + VSV + + G +V ATA DT LGG FD LVNH
Sbjct: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
Query: 243 FMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLS-SSTQATLEIDSLFEGVDFYTSITR 301
F EEF +K+ D+ RAL RL CE+ K+ +S +++ L I+ VD ++ R
Sbjct: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
Query: 302 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKEL 361
+F E+C+DL P+ L KL K I+ V +VGG+TRIP V++ + FF GKEL
Sbjct: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
Query: 362 NKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLE-----TAGGVMTTLI 416
+ ++N DEAV G A+Q A+L KV++ + DV P + L G +
Sbjct: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
Query: 417 QRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-VPQ 475
+N P + TF +P Y + + + + +F + + P G +
Sbjct: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
Query: 476 IEVTFDIDANGILSVTA---TDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDE 532
++V ++ +GI SV++ + + N+ + D+ +KEE + V + E + E
Sbjct: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHV---E 532
Query: 533 AQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQ 573
Q+ + A+N E+ + ++ D+ P+ + K++
Sbjct: 533 EQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVK 573
>gi|48928056 heat shock protein 70kDa family member 13 precursor
[Homo sapiens]
Length = 471
Score = 279 bits (713), Expect = 7e-75
Identities = 165/423 (39%), Positives = 247/423 (58%), Gaps = 50/423 (11%)
Query: 4 PRELAVGIDLGTTYSCVGVF--QQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQA 61
P +GIDLGTTY VGVF G+V+++ ++ G+ + PS V+FTD + VG + A
Sbjct: 29 PTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELA 88
Query: 62 ALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEI 121
NP NT++DAKR IG+ F +++++ +PF+V+++ G + V E T PE +
Sbjct: 89 DSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYV 147
Query: 122 SSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAA 181
S +L K+KE AEAYLG PV +AVI+VPA F+ QR +T +A +AGL +LR+INEPTAA
Sbjct: 148 GSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAA 207
Query: 182 AIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVN 241
A+AYGL + A +VL+ DLGGGT DVS+L+ G+F +A +G+ LGG+DF+ RL+
Sbjct: 208 AMAYGLHK--ADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQ 265
Query: 242 HFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEI--------------- 286
+ ++ + +G + K + RLR A E K L+ A L +
Sbjct: 266 YLYKQIYQTYG-FVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSS 324
Query: 287 ------DSLFEGVD----------------------FYTSITRARFEELCSDLFRSTLEP 318
D L D F T I+R F+ L DLF+ L P
Sbjct: 325 DTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVP 384
Query: 319 VEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQ 378
+++ L++ L+K +I +VVLVGGSTRIP++++++Q+FF GK+ N S++PD AV G A+Q
Sbjct: 385 IQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQ 443
Query: 379 AAV 381
A +
Sbjct: 444 AGI 446
>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
Length = 839
Score = 269 bits (687), Expect = 7e-72
Identities = 174/572 (30%), Positives = 297/572 (51%), Gaps = 28/572 (4%)
Query: 9 VGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNT 68
VGIDLG + V + G +E +AN+ +R TP+ ++ R +G+AAKSQ N NT
Sbjct: 4 VGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNT 63
Query: 69 VFDAKRLIGRKFADTTVQSDMKHWPFRVVS-EGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
+ K+L GR F D VQ++ P+ + G V+V Y E++ F E+++ M+L+
Sbjct: 64 IHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLA 123
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
K+KET+E L +PV VI++P++F D++R++ A +AGLN LR++NE TA A+AYG+
Sbjct: 124 KLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGI 183
Query: 188 DRR-----GAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNH 242
++ RNV+ D+G + V V + + G +V AT D +LGG +FD LV++
Sbjct: 184 YKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALVDY 243
Query: 243 FMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLS-SSTQATLEIDSLFEGVDFYTSITR 301
F +EF+ K+ ++ N RAL RL CE+ K+ +S +++ L I+ +D + + R
Sbjct: 244 FCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNR 303
Query: 302 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKEL 361
A+FE+LC+ L P++ + A L + I + +VGG+TRIP V++ + FF K++
Sbjct: 304 AQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFL-KDI 362
Query: 362 NKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLE-----TAGGVMTTLI 416
+ ++N DEAVA G A+Q A+L KV++ + D+ P S+ L G +
Sbjct: 363 STTLNADEAVARGCALQCAIL--SPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVF 420
Query: 417 QRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-VPQ 475
+N P + TF +P Y + + +G F + + P G +
Sbjct: 421 CKNHPAPFSKVITF---HKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSSK 477
Query: 476 IEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHE----AEQYKAED 531
++V ++ +GI SV S K + D E +E ++ + +
Sbjct: 478 VKVKVRVNIHGIFSVA----SASVIEKQNLEGDHSDAPMETETSFKNENKDNMDKMQVDQ 533
Query: 532 EAQRDRVAAKNSLEAHVFHVKGSLQEESLRDK 563
E + A+++ E + H G+ + ++ DK
Sbjct: 534 EEGHQKCHAEHTPEEEIDHT-GAKTKSAVSDK 564
Score = 30.0 bits (66), Expect = 6.9
Identities = 22/83 (26%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 530 EDEAQRDRVAAKNSLEAHVFHVK---GSLQEESLRDKIPEEDRRKMQDKCREVLAWL-EH 585
+D+ +++R AKN++E +V+ + G++ E+ I ED K+ + WL E
Sbjct: 610 QDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKF----ITPEDLSKLSAVLEDTENWLYED 665
Query: 586 NQLAEKEEYEHQKRELEQICRPI 608
+ K+ Y + +EL++ +PI
Sbjct: 666 GEDQPKQVYVDKLQELKKYGQPI 688
>gi|42544159 heat shock 105kD [Homo sapiens]
Length = 858
Score = 267 bits (683), Expect = 2e-71
Identities = 167/497 (33%), Positives = 269/497 (54%), Gaps = 21/497 (4%)
Query: 9 VGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNT 68
VG+D+G+ + V + G +E +AN+ +R TPS ++F R +G AAK+Q + +NT
Sbjct: 4 VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63
Query: 69 VFDAKRLIGRKFADTTVQSDMKHWPFRVVS-EGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
V + KR GR F D +Q + ++ + +V + G ++V Y GE+ F E+I++M+L+
Sbjct: 64 VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
K+KETAE L +PV VI+VP++F D++R++ DA I GLN LR++N+ TA A+ YG+
Sbjct: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183
Query: 188 DRRGAGE-----RNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNH 242
++ R V+ D+G F VS + + G +V TA D LGG++FD +LV H
Sbjct: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243
Query: 243 FMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSS-STQATLEIDSLFEGVDFYTSITR 301
F EF+ K+ D RAL RL CE+ K+ +SS ST L I+ D + R
Sbjct: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303
Query: 302 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKEL 361
++FEELC++L + P+ L L + V +VGG+TRIP V++ + FF GK++
Sbjct: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362
Query: 362 NKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGL------ETAGGVMTTL 415
+ ++N DEAVA G A+Q A+L KV++ + D P + L E GV +
Sbjct: 363 STTLNADEAVARGCALQCAIL--SPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV-HEV 419
Query: 416 IQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-VP 474
RN P + TF + F Y + + +GRF + + G
Sbjct: 420 FSRNHAAPFSKVLTFLRRGPFELEAF---YSDPQGVPYPEAKIGRFVVQNVSAQKDGEKS 476
Query: 475 QIEVTFDIDANGILSVT 491
+++V ++ +GI +++
Sbjct: 477 RVKVKVRVNTHGIFTIS 493
>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 229 bits (585), Expect = 5e-60
Identities = 183/620 (29%), Positives = 295/620 (47%), Gaps = 63/620 (10%)
Query: 9 VGIDLGTTYSCVGVFQQG-RVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A S A NP
Sbjct: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
Query: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
T+ + L+G++ + V +P ++ + + F PEE+ MVL+
Sbjct: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLN 155
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
+ AE + QP+K AVITVP +FN ++R+A A +AGL VL++IN+ TA A++YG+
Sbjct: 156 YSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGV 215
Query: 188 DRR---GAGERNVLIFDLGGGTFDVSVLSI------DAGV---FEVKATAGDTHLGGEDF 235
RR +N++ +D+G G+ ++++ +AG+ +++ D LGG +
Sbjct: 216 FRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEM 275
Query: 236 D----NRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFE 291
+ RL F E+ + + KD+ N RA+ +L R K LS++ +I+ L +
Sbjct: 276 ELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMD 335
Query: 292 GVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKL 351
VDF +TR FEELC+DLF PV++AL+ A++ +I V+LVGG+TR+P+VQ++
Sbjct: 336 DVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEV 395
Query: 352 LQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLD--VAPLSL------ 403
L +EL K+IN DEA A GA QAA L K KV+ ++ D V P+ +
Sbjct: 396 LLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFTREV 453
Query: 404 ----GLETAGGVMTTLIQRNATIPTKQTQTFTTYSD------NQPGVFIQVYEGERAMTK 453
G+ + L R P ++ TF YS N + E R
Sbjct: 454 EEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGS 513
Query: 454 DNNLLGRFELSGIPPAPRGVPQ-----IEVTFDIDANGILSV--------TATDRSTGKA 500
N L +L G+ + + P I+ F++D +G+LS+ T + S +
Sbjct: 514 QN--LTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEE 571
Query: 501 NKIT-ITNDKGRL--------SKEEVERMVHEAEQYKAEDEAQR--DRVAAKNSLEAHVF 549
+ +T + N L +KE V E E+ AE ++V K EA V
Sbjct: 572 STLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVE 631
Query: 550 HVKGSLQEESLRDKIPEEDR 569
E D PE ++
Sbjct: 632 DGSQPPPPEPKGDATPEGEK 651
Score = 50.4 bits (119), Expect = 5e-06
Identities = 56/273 (20%), Positives = 106/273 (38%), Gaps = 45/273 (16%)
Query: 378 QAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTY---- 433
++ VL D+ E V + L+ D A L G +++L T K+ T T
Sbjct: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
Query: 434 -----SDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG--VPQIEVTFDID--- 483
S ++PG +++ E A +D + PP P+G P+ E + +
Sbjct: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659
Query: 484 --------------ANGILSVTATDRSTGKANKITITNDKG---------RLSKEEVERM 520
G+ ++ A K + + G L ++++ +
Sbjct: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719
Query: 521 VHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVL 580
V + + D +++R A NSLEA +F + L + ++ EE R ++ K
Sbjct: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779
Query: 581 AWLEHNQL-AEKEEYEHQKRELEQICRPIFSRL 612
WLE + A + + EL ++C+ +F R+
Sbjct: 780 TWLEDEGVGATTVMLKEKLAELRKLCQGLFFRV 812
>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 229 bits (585), Expect = 5e-60
Identities = 183/620 (29%), Positives = 295/620 (47%), Gaps = 63/620 (10%)
Query: 9 VGIDLGTTYSCVGVFQQG-RVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A S A NP
Sbjct: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
Query: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
T+ + L+G++ + V +P ++ + + F PEE+ MVL+
Sbjct: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLN 155
Query: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
+ AE + QP+K AVITVP +FN ++R+A A +AGL VL++IN+ TA A++YG+
Sbjct: 156 YSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGV 215
Query: 188 DRR---GAGERNVLIFDLGGGTFDVSVLSI------DAGV---FEVKATAGDTHLGGEDF 235
RR +N++ +D+G G+ ++++ +AG+ +++ D LGG +
Sbjct: 216 FRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEM 275
Query: 236 D----NRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFE 291
+ RL F E+ + + KD+ N RA+ +L R K LS++ +I+ L +
Sbjct: 276 ELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMD 335
Query: 292 GVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKL 351
VDF +TR FEELC+DLF PV++AL+ A++ +I V+LVGG+TR+P+VQ++
Sbjct: 336 DVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEV 395
Query: 352 LQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLD--VAPLSL------ 403
L +EL K+IN DEA A GA QAA L K KV+ ++ D V P+ +
Sbjct: 396 LLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFTREV 453
Query: 404 ----GLETAGGVMTTLIQRNATIPTKQTQTFTTYSD------NQPGVFIQVYEGERAMTK 453
G+ + L R P ++ TF YS N + E R
Sbjct: 454 EEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGS 513
Query: 454 DNNLLGRFELSGIPPAPRGVPQ-----IEVTFDIDANGILSV--------TATDRSTGKA 500
N L +L G+ + + P I+ F++D +G+LS+ T + S +
Sbjct: 514 QN--LTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEE 571
Query: 501 NKIT-ITNDKGRL--------SKEEVERMVHEAEQYKAEDEAQR--DRVAAKNSLEAHVF 549
+ +T + N L +KE V E E+ AE ++V K EA V
Sbjct: 572 STLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVE 631
Query: 550 HVKGSLQEESLRDKIPEEDR 569
E D PE ++
Sbjct: 632 DGSQPPPPEPKGDATPEGEK 651
Score = 50.4 bits (119), Expect = 5e-06
Identities = 56/273 (20%), Positives = 106/273 (38%), Gaps = 45/273 (16%)
Query: 378 QAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTY---- 433
++ VL D+ E V + L+ D A L G +++L T K+ T T
Sbjct: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
Query: 434 -----SDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG--VPQIEVTFDID--- 483
S ++PG +++ E A +D + PP P+G P+ E + +
Sbjct: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659
Query: 484 --------------ANGILSVTATDRSTGKANKITITNDKG---------RLSKEEVERM 520
G+ ++ A K + + G L ++++ +
Sbjct: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719
Query: 521 VHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVL 580
V + + D +++R A NSLEA +F + L + ++ EE R ++ K
Sbjct: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779
Query: 581 AWLEHNQL-AEKEEYEHQKRELEQICRPIFSRL 612
WLE + A + + EL ++C+ +F R+
Sbjct: 780 TWLEDEGVGATTVMLKEKLAELRKLCQGLFFRV 812
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 38.5 bits (88), Expect = 0.019
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 2/128 (1%)
Query: 477 EVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRD 536
E+T DA L VT T + ++ G + ++ + + +AE + E+ QR
Sbjct: 1579 ELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1638
Query: 537 -RVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYE 595
VAA+ LE + +K + + + RKMQ + +E+ +E + +EE
Sbjct: 1639 LAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR-TSREEIF 1697
Query: 596 HQKRELEQ 603
Q RE E+
Sbjct: 1698 SQNRESEK 1705
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 38.5 bits (88), Expect = 0.019
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 2/128 (1%)
Query: 477 EVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRD 536
E+T DA L VT T + ++ G + ++ + + +AE + E+ QR
Sbjct: 1571 ELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1630
Query: 537 -RVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYE 595
VAA+ LE + +K + + + RKMQ + +E+ +E + +EE
Sbjct: 1631 LAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR-TSREEIF 1689
Query: 596 HQKRELEQ 603
Q RE E+
Sbjct: 1690 SQNRESEK 1697
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 38.5 bits (88), Expect = 0.019
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 2/128 (1%)
Query: 477 EVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRD 536
E+T DA L VT T + ++ G + ++ + + +AE + E+ QR
Sbjct: 1612 ELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1671
Query: 537 -RVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYE 595
VAA+ LE + +K + + + RKMQ + +E+ +E + +EE
Sbjct: 1672 LAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR-TSREEIF 1730
Query: 596 HQKRELEQ 603
Q RE E+
Sbjct: 1731 SQNRESEK 1738
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 38.5 bits (88), Expect = 0.019
Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 30/115 (26%)
Query: 509 KGRLSKEEVERMVHEAEQYKAEDEAQR--------------DRVAAKNSLEAHV-----F 549
K +LS EE+ER E E+ KAE+EA+R + V +S E + F
Sbjct: 309 KLKLSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEF 368
Query: 550 HVKGSLQ---EESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKREL 601
G L+ EE L+ K+ EE RR +++ +H EK+E+E ++E+
Sbjct: 369 LTPGKLEINFEELLKQKMEEEKRRTEEER--------KHKLEMEKQEFEQLRQEM 415
Score = 35.4 bits (80), Expect = 0.16
Identities = 30/116 (25%), Positives = 52/116 (44%), Gaps = 14/116 (12%)
Query: 488 LSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAH 547
LS+ D +A K +++ K +L+ EE+ER E + +AE+EA++ K +
Sbjct: 225 LSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKRAF--- 281
Query: 548 VFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQ 603
EE+ R + E++ QD + + EE E Q+RE E+
Sbjct: 282 ---------EEARRQMVNEDEEN--QDTAKIFKGYRPGKLKLSFEEMERQRREDEK 326
Score = 29.6 bits (65), Expect = 9.0
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Query: 505 ITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQ------EE 558
I ++ R ++E EAE + ED+ + H ++K + EE
Sbjct: 467 IEEERARRRAIDLEIKEREAENFHEEDDVDVRPARKSEAPFTHKVNMKARFEQMAKAREE 526
Query: 559 SLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEE 593
+ +I E+ +MQ + RE+ A L+ + E+EE
Sbjct: 527 EEQRRIEEQKLLRMQFEQREIDAALQKKREEEEEE 561
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 37.4 bits (85), Expect = 0.043
Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 12/101 (11%)
Query: 505 ITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNS-LEAHVFHVKGSLQEESLRDK 563
+T +K L E++ E E Y AE E R R+AAK LE + ++ L+EE R +
Sbjct: 885 LTEEKNLLQ----EQLQAETELY-AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ 939
Query: 564 IPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQI 604
+ +R+KM + L+ + E+EE QK +LE++
Sbjct: 940 QLQAERKKMAQQ------MLDLEEQLEEEEAARQKLQLEKV 974
Score = 34.3 bits (77), Expect = 0.36
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 22/112 (19%)
Query: 513 SKEEVERMVHEAEQYKAEDEAQRDRVA---------------AKNSLEAHVFHVKGSLQE 557
SK++V + VHE E+ K E Q + + AK LE ++ +KG +
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
Query: 558 E-SLRDKIPEEDRRKMQDKCREVLAWLEHNQ------LAEKEEYEHQKRELE 602
+ RD+ EE RR++Q + E LE + A K++ E ++LE
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
Score = 29.6 bits (65), Expect = 9.0
Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 492 ATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHV 551
AT+RST + N+ + +E+ +HE E A + +AA LEA + +
Sbjct: 1774 ATERSTAQKNESA--RQQLERQNKELRSKLHEMEG--AVKSKFKSTIAA---LEAKIAQL 1826
Query: 552 KGSLQEESLRDKIPEEDRRKMQDKCREVLAWLE-HNQLAE--KEEYEHQKRELEQICRPI 608
+ +++E+ + + ++ K +E+L +E ++AE KE+ E ++Q+ R +
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 37.4 bits (85), Expect = 0.043
Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 12/101 (11%)
Query: 505 ITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNS-LEAHVFHVKGSLQEESLRDK 563
+T +K L E++ E E Y AE E R R+AAK LE + ++ L+EE R +
Sbjct: 892 LTEEKNLLQ----EQLQAETELY-AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ 946
Query: 564 IPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQI 604
+ +R+KM + L+ + E+EE QK +LE++
Sbjct: 947 QLQAERKKMAQQ------MLDLEEQLEEEEAARQKLQLEKV 981
Score = 34.3 bits (77), Expect = 0.36
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 22/112 (19%)
Query: 513 SKEEVERMVHEAEQYKAEDEAQRDRVA---------------AKNSLEAHVFHVKGSLQE 557
SK++V + VHE E+ K E Q + + AK LE ++ +KG +
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585
Query: 558 E-SLRDKIPEEDRRKMQDKCREVLAWLEHNQ------LAEKEEYEHQKRELE 602
+ RD+ EE RR++Q + E LE + A K++ E ++LE
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1637
Score = 29.6 bits (65), Expect = 9.0
Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 492 ATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHV 551
AT+RST + N+ + +E+ +HE E A + +AA LEA + +
Sbjct: 1781 ATERSTAQKNESA--RQQLERQNKELRSKLHEMEG--AVKSKFKSTIAA---LEAKIAQL 1833
Query: 552 KGSLQEESLRDKIPEEDRRKMQDKCREVLAWLE-HNQLAE--KEEYEHQKRELEQICRPI 608
+ +++E+ + + ++ K +E+L +E ++AE KE+ E ++Q+ R +
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 37.4 bits (85), Expect = 0.043
Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 12/101 (11%)
Query: 505 ITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNS-LEAHVFHVKGSLQEESLRDK 563
+T +K L E++ E E Y AE E R R+AAK LE + ++ L+EE R +
Sbjct: 892 LTEEKNLLQ----EQLQAETELY-AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ 946
Query: 564 IPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQI 604
+ +R+KM + L+ + E+EE QK +LE++
Sbjct: 947 QLQAERKKMAQQ------MLDLEEQLEEEEAARQKLQLEKV 981
Score = 34.3 bits (77), Expect = 0.36
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 22/112 (19%)
Query: 513 SKEEVERMVHEAEQYKAEDEAQRDRVA---------------AKNSLEAHVFHVKGSLQE 557
SK++V + VHE E+ K E Q + + AK LE ++ +KG +
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585
Query: 558 E-SLRDKIPEEDRRKMQDKCREVLAWLEHNQ------LAEKEEYEHQKRELE 602
+ RD+ EE RR++Q + E LE + A K++ E ++LE
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1637
Score = 29.6 bits (65), Expect = 9.0
Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 492 ATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHV 551
AT+RST + N+ + +E+ +HE E A + +AA LEA + +
Sbjct: 1781 ATERSTAQKNESA--RQQLERQNKELRSKLHEMEG--AVKSKFKSTIAA---LEAKIAQL 1833
Query: 552 KGSLQEESLRDKIPEEDRRKMQDKCREVLAWLE-HNQLAE--KEEYEHQKRELEQICRPI 608
+ +++E+ + + ++ K +E+L +E ++AE KE+ E ++Q+ R +
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 37.4 bits (85), Expect = 0.043
Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 12/101 (11%)
Query: 505 ITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNS-LEAHVFHVKGSLQEESLRDK 563
+T +K L E++ E E Y AE E R R+AAK LE + ++ L+EE R +
Sbjct: 885 LTEEKNLLQ----EQLQAETELY-AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ 939
Query: 564 IPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQI 604
+ +R+KM + L+ + E+EE QK +LE++
Sbjct: 940 QLQAERKKMAQQ------MLDLEEQLEEEEAARQKLQLEKV 974
Score = 34.3 bits (77), Expect = 0.36
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 22/112 (19%)
Query: 513 SKEEVERMVHEAEQYKAEDEAQRDRVA---------------AKNSLEAHVFHVKGSLQE 557
SK++V + VHE E+ K E Q + + AK LE ++ +KG +
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
Query: 558 E-SLRDKIPEEDRRKMQDKCREVLAWLEHNQ------LAEKEEYEHQKRELE 602
+ RD+ EE RR++Q + E LE + A K++ E ++LE
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
Score = 29.6 bits (65), Expect = 9.0
Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 492 ATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHV 551
AT+RST + N+ + +E+ +HE E A + +AA LEA + +
Sbjct: 1774 ATERSTAQKNESA--RQQLERQNKELRSKLHEMEG--AVKSKFKSTIAA---LEAKIAQL 1826
Query: 552 KGSLQEESLRDKIPEEDRRKMQDKCREVLAWLE-HNQLAE--KEEYEHQKRELEQICRPI 608
+ +++E+ + + ++ K +E+L +E ++AE KE+ E ++Q+ R +
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 37.0 bits (84), Expect = 0.056
Identities = 25/88 (28%), Positives = 49/88 (55%), Gaps = 8/88 (9%)
Query: 518 ERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFH-VKGSLQEESLRDKIPEEDRRKMQDKC 576
E++ E E + AE E R R+AAK + H ++ ++EE R++I + +++KMQ
Sbjct: 894 EQLQAETELF-AEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHI 952
Query: 577 REVLAWLEHNQLAEKEEYEHQKRELEQI 604
+++ + ++EE QK +LE++
Sbjct: 953 QDL------EEQLDEEEGARQKLQLEKV 974
Score = 32.0 bits (71), Expect = 1.8
Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 514 KEEVERMVHEAEQYKAEDEAQRDRVA--AKNSLEAHVFHVKGSL-QEESLRDKIPEED-- 568
K+E+E ++H+ E + E+E +R+++ K ++AH+ ++ L +EE R K+ E
Sbjct: 917 KQELEEILHDLES-RVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVT 975
Query: 569 -RRKMQDKCREVLAWLEHNQLAEKEE 593
K++ E+L + N KE+
Sbjct: 976 AEAKIKKMEEEILLLEDQNSKFIKEK 1001
Score = 30.8 bits (68), Expect = 4.0
Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 24/113 (21%)
Query: 513 SKEEVERMVHEAEQYK----------------AEDEAQRDRVAAKNSLEAHVFHVKGSLQ 556
SK++V + VHE E+ K EDE Q AK LE ++ +K +
Sbjct: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE-DAKLRLEVNMQAMKAQFE 1577
Query: 557 EE-SLRDKIPEEDRRKMQDKCREVLAWLEHNQ------LAEKEEYEHQKRELE 602
+ RD+ EE +R + + RE+ A LE + +A K++ E ++LE
Sbjct: 1578 RDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE 1630
>gi|38348298 ankyrin repeat domain 45 [Homo sapiens]
Length = 266
Score = 36.6 bits (83), Expect = 0.073
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Query: 536 DRVAAKNSLEAHVFHVKGSLQE-ESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEY 594
D A+ +L+ ++ V ++ + E K+ +ED+ + CR WLE + A E
Sbjct: 163 DWADARLTLKKYIAKVSLAVTDTEKGSGKLLKEDKNTILSACRAKNEWLETHTEASINEL 222
Query: 595 EHQKRELEQICRPIFSRL 612
Q+++LE I PIF+++
Sbjct: 223 FEQRQQLEDIVTPIFTKM 240
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 35.8 bits (81), Expect = 0.13
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 493 TDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVK 552
T+R + K + D+ +E ER + E+ + E + +R++ + E +K
Sbjct: 464 TERHEQERRKQQLKRDQ---EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520
Query: 553 GSLQEESLRDKIPEEDR-RKMQDKCREVLAWLEHNQLAEKEEYEHQ-KRELEQ 603
+EE L+ ++ E + R+ Q++ RE L E + E+E E + KRE E+
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Score = 33.1 bits (74), Expect = 0.81
Identities = 24/107 (22%), Positives = 50/107 (46%), Gaps = 2/107 (1%)
Query: 494 DRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKG 553
DR + ++ ++ +L ++E +R E EQ E +R + + L K
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 554 SLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRE 600
+EE LR + +E R+ Q++ R++L + E+++ Q+R+
Sbjct: 1726 R-EEEQLRQETEQEQLRR-QERYRKILEEEQLRPEREEQQLRRQERD 1770
Score = 33.1 bits (74), Expect = 0.81
Identities = 24/101 (23%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 508 DKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLR----DK 563
++ +L ++E+ER E EQ + E E ++ R + ++ +E+ LR D+
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 564 IPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQI 604
E+ + Q++ + L E ++ +EE Q+RE +Q+
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Score = 32.7 bits (73), Expect = 1.1
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 11/107 (10%)
Query: 511 RLSKEEVERMVHEAEQ----YKAEDEAQRDRVAAKNSLEAHVFHVKGSL----QEESLRD 562
R +EE HE E+ K E E +RD + + E H + QEE R+
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 563 ---KIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICR 606
K+ EE+RR+ Q++ + L + + ++ + + ++ L+Q R
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Score = 31.6 bits (70), Expect = 2.4
Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 14/116 (12%)
Query: 502 KITITNDKGRLSKEEVE--RMVHEAEQYKAEDEAQR--------DRVAAKNSLEAHVFHV 551
K + ++ +L +EE E R+ QY+ E+E Q+ +R + +
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 552 KGSLQ--EESLRDKIPEEDRRKMQDK-CR-EVLAWLEHNQLAEKEEYEHQKRELEQ 603
+ LQ EE L + PE+ RR+ +++ CR E E QL +E + +++ELE+
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138
Score = 31.6 bits (70), Expect = 2.4
Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 494 DRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKG 553
DR + ++ ++ +LS++E +R EQ E +R + + L +G
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ----EG 1609
Query: 554 SLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICR 606
Q RD+ ED + +Q++ + L E ++ +EE + +++E EQ R
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Score = 30.4 bits (67), Expect = 5.3
Identities = 26/108 (24%), Positives = 50/108 (46%), Gaps = 13/108 (12%)
Query: 511 RLSKEEVERMVHEA------EQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKI 564
RL +EEVER+ E ++ + E+E ++ + ++ E ++ QE +
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 565 PEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQICRPIFSRL 612
EE+ +++ + + EH + E+ E E + E EQ I SR+
Sbjct: 661 REEEEERLEQRLKR-----EHEE--ERREQELAEEEQEQARERIKSRI 701
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 35.8 bits (81), Expect = 0.13
Identities = 37/147 (25%), Positives = 64/147 (43%), Gaps = 12/147 (8%)
Query: 465 GIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLS--------KEE 516
G P + + +E++ D I S T K + + + LS +EE
Sbjct: 863 GKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEE 922
Query: 517 VERMVHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKC 576
ER+ E+ + E + +R+ + E +K L+ E+ R K EE+R+K +D
Sbjct: 923 AERLRRIQEEMEKERK-RREEDEKRRRKEEEERRMK--LEMEAKR-KQEEEERKKREDDE 978
Query: 577 REVLAWLEHNQLAEKEEYEHQKRELEQ 603
+ + A +E +KEE Q+ LEQ
Sbjct: 979 KRIQAEVEAQLARQKEEESQQQAVLEQ 1005
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 35.8 bits (81), Expect = 0.13
Identities = 63/344 (18%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 275 TLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIH 334
+L + + L+ D L E V + FE + +L T++ AL+ AKLD+ +
Sbjct: 685 SLYTQNSSILDNDILNEPVP--PEMNEQAFEAISEEL--RTVQEQMSALQ-AKLDEEEHK 739
Query: 335 DVVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLL 394
++ L ++ +Q+ F+ + ++ + +E ++ ++ + + + D L
Sbjct: 740 NLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQL---QETQTKNDFL 796
Query: 395 LLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVFIQV----YEGERA 450
+V L + L +A ++++ ++ T Q + F S+ V +Q+ E E+
Sbjct: 797 KSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKL 856
Query: 451 MTKD-------NNL--LGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGKAN 501
+ +NL + +FE+ + + + T D N ++ + ++
Sbjct: 857 LESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKL 916
Query: 502 KITITNDKGRLSKEEVERMVHEAEQYKAEDEAQRDRVAAK-NSLEAHVFHVKGSLQEESL 560
+ DK SK E+ +++ Q K ++ A+ ++ AK LE + + + S
Sbjct: 917 SLQFEEDKENSSK-EILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVI---SS 972
Query: 561 RDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQI 604
+K + D++ + D ++ L + + E + K+EL+ I
Sbjct: 973 LEKSRDSDKKVVADLMNQIQE-LRTSVCEKTETIDTLKQELKDI 1015
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 35.8 bits (81), Expect = 0.13
Identities = 28/110 (25%), Positives = 54/110 (49%), Gaps = 9/110 (8%)
Query: 495 RSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAED-EAQRDRVAAKNSLEAHVFHVKG 553
RS + + + + R +++ + E E+ K +D E +R+R + + +G
Sbjct: 358 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE-----RG 412
Query: 554 SLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYEHQKRELEQ 603
++ RDK E+DR K ++K RE EH + +KE+ + Q +E E+
Sbjct: 413 KNKD---RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,426,224
Number of Sequences: 37866
Number of extensions: 1057479
Number of successful extensions: 4348
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 123
Number of HSP's that attempted gapping in prelim test: 3963
Number of HSP's gapped (non-prelim): 478
length of query: 643
length of database: 18,247,518
effective HSP length: 109
effective length of query: 534
effective length of database: 14,120,124
effective search space: 7540146216
effective search space used: 7540146216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.