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Search of human proteins with 34304354
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34304354 phosphatase and actin regulator 3 isoform 2 [Homo
sapiens]
(518 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34304354 phosphatase and actin regulator 3 isoform 2 [Homo sa... 1020 0.0
gi|18087853 phosphatase and actin regulator 3 isoform 1 [Homo sa... 1020 0.0
gi|34304356 phosphatase and actin regulator 3 isoform 3 [Homo sa... 800 0.0
gi|54144631 phosphatase and actin regulator 1 [Homo sapiens] 358 7e-99
gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo s... 291 1e-78
gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo s... 291 1e-78
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s... 229 5e-60
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s... 229 5e-60
gi|115430209 phosphatase and actin regulator 4 isoform 2 [Homo s... 218 8e-57
gi|115430211 phosphatase and actin regulator 4 isoform 1 [Homo s... 218 8e-57
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 56 7e-08
gi|56549694 enabled homolog isoform a [Homo sapiens] 51 2e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 51 2e-06
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 50 4e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 49 1e-05
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 48 2e-05
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 47 3e-05
gi|148727255 microtubule associated serine/threonine kinase fami... 47 3e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 47 3e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 5e-05
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 46 9e-05
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 46 9e-05
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 46 9e-05
gi|148746195 trichohyalin [Homo sapiens] 45 1e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 45 2e-04
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 45 2e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 45 2e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 45 2e-04
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 45 2e-04
>gi|34304354 phosphatase and actin regulator 3 isoform 2 [Homo
sapiens]
Length = 518
Score = 1020 bits (2637), Expect = 0.0
Identities = 518/518 (100%), Positives = 518/518 (100%)
Query: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAG 60
MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAG
Sbjct: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAG 60
Query: 61 RQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATG 120
RQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATG
Sbjct: 61 RQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATG 120
Query: 121 TDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPL 180
TDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPL
Sbjct: 121 TDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPL 180
Query: 181 ERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHL 240
ERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHL
Sbjct: 181 ERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHL 240
Query: 241 TTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREE 300
TTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREE
Sbjct: 241 TTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREE 300
Query: 301 AWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKE 360
AWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKE
Sbjct: 301 AWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKE 360
Query: 361 LLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILK 420
LLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILK
Sbjct: 361 LLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILK 420
Query: 421 QRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPW 480
QRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPW
Sbjct: 421 QRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPW 480
Query: 481 TRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 518
TRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP
Sbjct: 481 TRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 518
>gi|18087853 phosphatase and actin regulator 3 isoform 1 [Homo
sapiens]
Length = 559
Score = 1020 bits (2637), Expect = 0.0
Identities = 518/518 (100%), Positives = 518/518 (100%)
Query: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAG 60
MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAG
Sbjct: 42 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAG 101
Query: 61 RQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATG 120
RQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATG
Sbjct: 102 RQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATG 161
Query: 121 TDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPL 180
TDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPL
Sbjct: 162 TDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPL 221
Query: 181 ERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHL 240
ERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHL
Sbjct: 222 ERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHL 281
Query: 241 TTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREE 300
TTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREE
Sbjct: 282 TTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREE 341
Query: 301 AWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKE 360
AWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKE
Sbjct: 342 AWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKE 401
Query: 361 LLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILK 420
LLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILK
Sbjct: 402 LLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILK 461
Query: 421 QRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPW 480
QRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPW
Sbjct: 462 QRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPW 521
Query: 481 TRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 518
TRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP
Sbjct: 522 TRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 559
>gi|34304356 phosphatase and actin regulator 3 isoform 3 [Homo
sapiens]
Length = 448
Score = 800 bits (2067), Expect = 0.0
Identities = 431/520 (82%), Positives = 433/520 (83%), Gaps = 74/520 (14%)
Query: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAG 60
MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAG
Sbjct: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAG 60
Query: 61 RQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATG 120
RQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTS
Sbjct: 61 RQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTS------------ 108
Query: 121 TDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGAD--SLDSPPR 178
E+A GS L T G D SLD P
Sbjct: 109 ----------------------------EDAQPGSPLAT---------GTDQVSLDKP-- 129
Query: 179 PLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSP 238
SS + GQATLFQASSMKSADPSLRGQLSTPTGSP
Sbjct: 130 ---------------------LSSAAHLDDAGQATLFQASSMKSADPSLRGQLSTPTGSP 168
Query: 239 HLTTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKER 298
HLTTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKER
Sbjct: 169 HLTTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKER 228
Query: 299 EEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCK 358
EEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCK
Sbjct: 229 EEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCK 288
Query: 359 KELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNI 418
KELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNI
Sbjct: 289 KELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNI 348
Query: 419 LKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADK 478
LKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADK
Sbjct: 349 LKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADK 408
Query: 479 PWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 518
PWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP
Sbjct: 409 PWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 448
>gi|54144631 phosphatase and actin regulator 1 [Homo sapiens]
Length = 580
Score = 358 bits (919), Expect = 7e-99
Identities = 239/539 (44%), Positives = 313/539 (58%), Gaps = 80/539 (14%)
Query: 8 RPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAGRQGREEL 67
R + LV G TPP+RR SK A LGRIFKPWKWRKKK+EK K T++ALE+K++ RQ REEL
Sbjct: 94 RSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREEL 153
Query: 68 IKKGLL-EMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSL 126
IK+G+L E+ ++D E N + + QS + Q+SL
Sbjct: 154 IKRGVLKEIYDKDGELSISNEEDSLENGQS----------------------LSSSQLSL 191
Query: 127 DKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQ 186
P+ S E +P + L +D +D P +
Sbjct: 192 ----------------PALSEMEPVP----MPRDPCSYEVLQPSDIMDGPDPGAPVKLPC 231
Query: 187 LP---SPPLLPTP---------PPKASSKTTKNVTGQATLFQASSMKSADPS-LRGQLST 233
LP SPPL P P + T +GQ + A + PS ++ QL
Sbjct: 232 LPVKLSPPLPPKKVMICMPVGGPDLSLVSYTAQKSGQQGV--AQHHHTVLPSQIQHQLQY 289
Query: 234 PTGSPHL--TTVHRPLPPS--RVIEELHRALA-TKHRQDSFQGRESKGSPKKRLDVRLSR 288
+ HL TT P+ PS R+I+EL++ LA T R +S + R +
Sbjct: 290 GSHGQHLPSTTGSLPMHPSGCRMIDELNKTLAMTMQRLESSEQRVPCSTSY--------H 341
Query: 289 TSSVERGKEREEAWSFD-GALENKRTAAKESEENKENLIINSELKDDLLLY-------QD 340
+S + G +A + T E ++NKEN+ S+ +D LY ++
Sbjct: 342 SSGLHSGDGVTKAGPMGLPEIRQVPTVVIECDDNKENVPHESDYEDSSCLYTREEEEEEE 401
Query: 341 EEALNDSIISGTLPRK-CKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMK 399
+E + S+ + +L K C+K+ LA+KL NRPSK+ELE++NI PR+TDEER E+RQQI K
Sbjct: 402 DEDDDSSLYTSSLAMKVCRKDSLAIKLSNRPSKRELEEKNILPRQTDEERLELRQQIGTK 461
Query: 400 LSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIR 459
L++RLSQRP EELE+RNILK RN+Q EQEE+REIK+RLTRKL+QRPTV+ELR+RKILIR
Sbjct: 462 LTRRLSQRPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERKILIR 521
Query: 460 FSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 518
FSDYVEVA AQDYDRRADKPWTRL+AADKAAIRKELNE+KS EMEVH S+HLTRFHRP
Sbjct: 522 FSDYVEVADAQDYDRRADKPWTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP 580
>gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo
sapiens]
Length = 554
Score = 291 bits (744), Expect = 1e-78
Identities = 202/556 (36%), Positives = 294/556 (52%), Gaps = 47/556 (8%)
Query: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMA 59
+D+ A + +G +TPP +R KL+T+G+IFKPWKWRKKK ++K ++T++ LE+K++
Sbjct: 8 LDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKIS 67
Query: 60 GRQGREELIKKGLL-EMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGS--- 115
RQ REELI++G+L E+ +QD + + + + + E + + GS
Sbjct: 68 TRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSE 127
Query: 116 ---PLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEE----------ADAGSL------ 156
PL + S A+ PS SS + AG++
Sbjct: 128 KTPPLEEQAEDKKAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGK 187
Query: 157 -----LPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQ 211
P T+ LS + + D P E V +P + + K K++
Sbjct: 188 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKF-KSMVPP 246
Query: 212 ATLFQASSMKSADPSLRGQLSTPTGSPH-LTTVHRPLPPSRVI-EELHRALATKHRQDSF 269
+ A S + L Q T + +P L +V LP S + +L A +R +
Sbjct: 247 PPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 306
Query: 270 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINS 329
G G R + + T E GK + + E+ + + +E N
Sbjct: 307 SGT---GLSVNRENAKCFTTKE-ELGKTVPQLLTPGLMGESSESFSASEDEGHREYQAND 362
Query: 330 ELKDDLLLY-------QDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 382
D +LY +DE+ +S ++ + R+ + LA+KL NRPSK+ELED+NI
Sbjct: 363 SDSDGPILYTDDEDEDEDEDGSGESALASKIRRR---DTLAIKLGNRPSKKELEDKNILQ 419
Query: 383 RRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 442
R ++EERQEIRQQI KL +RLSQRP EELE+RNILKQ+N++ EQE + E+K+RL+RKL
Sbjct: 420 RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKL 479
Query: 443 NQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNE 502
+ RPTV EL+ R+IL RF++YVEV + DYDRRADKPW RL+ ADKAAIRKELNE+KS E
Sbjct: 480 SLRPTVAELQARRIL-RFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTE 538
Query: 503 MEVHASSKHLTRFHRP 518
MEVH S+ TRFHRP
Sbjct: 539 MEVHEESRQFTRFHRP 554
>gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo
sapiens]
Length = 565
Score = 291 bits (744), Expect = 1e-78
Identities = 202/556 (36%), Positives = 294/556 (52%), Gaps = 47/556 (8%)
Query: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMA 59
+D+ A + +G +TPP +R KL+T+G+IFKPWKWRKKK ++K ++T++ LE+K++
Sbjct: 19 LDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKIS 78
Query: 60 GRQGREELIKKGLL-EMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGS--- 115
RQ REELI++G+L E+ +QD + + + + + E + + GS
Sbjct: 79 TRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSE 138
Query: 116 ---PLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEE----------ADAGSL------ 156
PL + S A+ PS SS + AG++
Sbjct: 139 KTPPLEEQAEDKKAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGK 198
Query: 157 -----LPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQ 211
P T+ LS + + D P E V +P + + K K++
Sbjct: 199 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKF-KSMVPP 257
Query: 212 ATLFQASSMKSADPSLRGQLSTPTGSPH-LTTVHRPLPPSRVI-EELHRALATKHRQDSF 269
+ A S + L Q T + +P L +V LP S + +L A +R +
Sbjct: 258 PPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 317
Query: 270 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINS 329
G G R + + T E GK + + E+ + + +E N
Sbjct: 318 SGT---GLSVNRENAKCFTTKE-ELGKTVPQLLTPGLMGESSESFSASEDEGHREYQAND 373
Query: 330 ELKDDLLLY-------QDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 382
D +LY +DE+ +S ++ + R+ + LA+KL NRPSK+ELED+NI
Sbjct: 374 SDSDGPILYTDDEDEDEDEDGSGESALASKIRRR---DTLAIKLGNRPSKKELEDKNILQ 430
Query: 383 RRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 442
R ++EERQEIRQQI KL +RLSQRP EELE+RNILKQ+N++ EQE + E+K+RL+RKL
Sbjct: 431 RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKL 490
Query: 443 NQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNE 502
+ RPTV EL+ R+IL RF++YVEV + DYDRRADKPW RL+ ADKAAIRKELNE+KS E
Sbjct: 491 SLRPTVAELQARRIL-RFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTE 549
Query: 503 MEVHASSKHLTRFHRP 518
MEVH S+ TRFHRP
Sbjct: 550 MEVHEESRQFTRFHRP 565
>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
sapiens]
Length = 634
Score = 229 bits (584), Expect = 5e-60
Identities = 164/436 (37%), Positives = 225/436 (51%), Gaps = 24/436 (5%)
Query: 98 PPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGS-- 155
PP P S T E A T + S SS + A+K +S
Sbjct: 208 PPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGK 267
Query: 156 ----LLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQ 211
P T+ LS + + D P E V +P + + K K++
Sbjct: 268 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKF-KSMVPP 326
Query: 212 ATLFQASSMKSADPSLRGQLSTPTGSPH-LTTVHRPLPPSRVI-EELHRALATKHRQDSF 269
+ A S + L Q T + +P L +V LP S + +L A +R +
Sbjct: 327 PPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 386
Query: 270 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINS 329
G G R + + T E GK + + E+ + + +E N
Sbjct: 387 SGT---GLSVNRENAKCFTTKE-ELGKTVPQLLTPGLMGESSESFSASEDEGHREYQAND 442
Query: 330 ELKDDLLLY-------QDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 382
D +LY +DE+ +S ++ + R+ + LA+KL NRPSK+ELED+NI
Sbjct: 443 SDSDGPILYTDDEDEDEDEDGSGESALASKIRRR---DTLAIKLGNRPSKKELEDKNILQ 499
Query: 383 RRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 442
R ++EERQEIRQQI KL +RLSQRP EELE+RNILKQ+N++ EQE + E+K+RL+RKL
Sbjct: 500 RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKL 559
Query: 443 NQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNE 502
+ RPTV EL+ R+IL RF++YVEV + DYDRRADKPW RL+ ADKAAIRKELNE+KS E
Sbjct: 560 SLRPTVAELQARRIL-RFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTE 618
Query: 503 MEVHASSKHLTRFHRP 518
MEVH S+ TRFHRP
Sbjct: 619 MEVHEESRQFTRFHRP 634
Score = 97.4 bits (241), Expect = 3e-20
Identities = 75/245 (30%), Positives = 120/245 (48%), Gaps = 10/245 (4%)
Query: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMA 59
+D+ A + +G +TPP +R KL+T+G+IFKPWKWRKKK ++K ++T++ LE+K++
Sbjct: 8 LDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKIS 67
Query: 60 GRQGREELIKKGLL-EMMEQDAE-SKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPG-SP 116
RQ REELI++G+L E+ +QD + + G E T + + SE+ S
Sbjct: 68 TRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSE 127
Query: 117 LATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNEL--SQALAGADSLD 174
++ + DK ++ H + A S P + + A AGA
Sbjct: 128 KTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKG 187
Query: 175 SPPRPLERSVGQLPSPPLLPTPPPK-ASSKTTKNVTGQATLFQASSMK-SADPSLRGQLS 232
P++++ + P P PPPK AS TT+ G + + + K SA PS S
Sbjct: 188 DEVPPIKKNT-KAPGKQ-APVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSS 245
Query: 233 TPTGS 237
P S
Sbjct: 246 RPKAS 250
>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
sapiens]
Length = 645
Score = 229 bits (584), Expect = 5e-60
Identities = 164/436 (37%), Positives = 225/436 (51%), Gaps = 24/436 (5%)
Query: 98 PPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGS-- 155
PP P S T E A T + S SS + A+K +S
Sbjct: 219 PPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGK 278
Query: 156 ----LLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQ 211
P T+ LS + + D P E V +P + + K K++
Sbjct: 279 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKF-KSMVPP 337
Query: 212 ATLFQASSMKSADPSLRGQLSTPTGSPH-LTTVHRPLPPSRVI-EELHRALATKHRQDSF 269
+ A S + L Q T + +P L +V LP S + +L A +R +
Sbjct: 338 PPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 397
Query: 270 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINS 329
G G R + + T E GK + + E+ + + +E N
Sbjct: 398 SGT---GLSVNRENAKCFTTKE-ELGKTVPQLLTPGLMGESSESFSASEDEGHREYQAND 453
Query: 330 ELKDDLLLY-------QDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 382
D +LY +DE+ +S ++ + R+ + LA+KL NRPSK+ELED+NI
Sbjct: 454 SDSDGPILYTDDEDEDEDEDGSGESALASKIRRR---DTLAIKLGNRPSKKELEDKNILQ 510
Query: 383 RRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 442
R ++EERQEIRQQI KL +RLSQRP EELE+RNILKQ+N++ EQE + E+K+RL+RKL
Sbjct: 511 RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKL 570
Query: 443 NQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNE 502
+ RPTV EL+ R+IL RF++YVEV + DYDRRADKPW RL+ ADKAAIRKELNE+KS E
Sbjct: 571 SLRPTVAELQARRIL-RFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTE 629
Query: 503 MEVHASSKHLTRFHRP 518
MEVH S+ TRFHRP
Sbjct: 630 MEVHEESRQFTRFHRP 645
Score = 97.4 bits (241), Expect = 3e-20
Identities = 75/245 (30%), Positives = 120/245 (48%), Gaps = 10/245 (4%)
Query: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMA 59
+D+ A + +G +TPP +R KL+T+G+IFKPWKWRKKK ++K ++T++ LE+K++
Sbjct: 19 LDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKIS 78
Query: 60 GRQGREELIKKGLL-EMMEQDAE-SKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPG-SP 116
RQ REELI++G+L E+ +QD + + G E T + + SE+ S
Sbjct: 79 TRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSE 138
Query: 117 LATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNEL--SQALAGADSLD 174
++ + DK ++ H + A S P + + A AGA
Sbjct: 139 KTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKG 198
Query: 175 SPPRPLERSVGQLPSPPLLPTPPPK-ASSKTTKNVTGQATLFQASSMK-SADPSLRGQLS 232
P++++ + P P PPPK AS TT+ G + + + K SA PS S
Sbjct: 199 DEVPPIKKNT-KAPGKQ-APVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSS 256
Query: 233 TPTGS 237
P S
Sbjct: 257 RPKAS 261
>gi|115430209 phosphatase and actin regulator 4 isoform 2 [Homo
sapiens]
Length = 712
Score = 218 bits (556), Expect = 8e-57
Identities = 157/417 (37%), Positives = 218/417 (52%), Gaps = 42/417 (10%)
Query: 129 PLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLP 188
P +S L+ AA + + + +E + +T + L S SP PL + P
Sbjct: 311 PSTSVPTLESAAAITTKTPSDEREK-----STCSMGSELLPMISPRSPSPPLPTHIP--P 363
Query: 189 SPPLLPTPPPKASSKTTK-----NVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTT- 242
PP P P K + ++ + Q K P + L G PH+ +
Sbjct: 364 EPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVP--KRILDQNFGEPHIPSR 421
Query: 243 -------------VHRPLPPSRVIEELHRALATK-HRQDSFQGRESKGSPKKRLDVRLSR 288
+ PLP + ++E HRA + DSF S + L + +
Sbjct: 422 LPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEM 481
Query: 289 TSSVERGKEREEAWSFDGALENKRTAA-------KESEENKENLIINSELKDDLLLYQDE 341
+ +E E+ + E T+ EE KE+ + + Y+DE
Sbjct: 482 LKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKES----DSDSEGPIQYRDE 537
Query: 342 EALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLS 401
E ++S S + +K+ LA+KL +RPS+ EL + N +P ++ EE EIR QI L
Sbjct: 538 EDEDESYQSALANKVKRKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLI 596
Query: 402 KRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFS 461
+RLSQRP EELE+RNIL+ +N+ Q E+REIK+RLTRKL+QRPTV EL RKIL RF+
Sbjct: 597 RRLSQRPTPEELEQRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKIL-RFN 655
Query: 462 DYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 518
+YVEV AQDYDRRADKPWT+L+ ADKAAIRKELNE+KS+EMEVH SKH TR+HRP
Sbjct: 656 EYVEVTDAQDYDRRADKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 712
Score = 90.9 bits (224), Expect = 3e-18
Identities = 82/281 (29%), Positives = 126/281 (44%), Gaps = 45/281 (16%)
Query: 14 SGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMAGRQGREELIKKG- 71
+G TPP +R SK + G+IFKPWKWRKKK ++K K+T+ LE+K++ R+ REEL+K+G
Sbjct: 34 AGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGV 93
Query: 72 LLEMMEQDAE-----------SKTCNPDGGPRS-----VQSEPPTPKS-----------E 104
LLE EQ E + P G RS V+ EP S +
Sbjct: 94 LLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKK 153
Query: 105 TLTSEDAQPGSPLATGTDQVSL------DKPLSSAAHLDDAAKMPSASSGEEADAGSLLP 158
L S +QP S + + V +PLSS+ + + SSG A ++
Sbjct: 154 RLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSG--GTARFIIS 211
Query: 159 TTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQ-- 216
T+ ++ A A + S + + SV P+P LP P ++ T ++T Q
Sbjct: 212 TS--ITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPP 269
Query: 217 ----ASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPSRVI 253
+ ++++P + L+ PLPP R I
Sbjct: 270 IPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGI 310
>gi|115430211 phosphatase and actin regulator 4 isoform 1 [Homo
sapiens]
Length = 702
Score = 218 bits (556), Expect = 8e-57
Identities = 157/417 (37%), Positives = 218/417 (52%), Gaps = 42/417 (10%)
Query: 129 PLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLP 188
P +S L+ AA + + + +E + +T + L S SP PL + P
Sbjct: 301 PSTSVPTLESAAAITTKTPSDEREK-----STCSMGSELLPMISPRSPSPPLPTHIP--P 353
Query: 189 SPPLLPTPPPKASSKTTK-----NVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTT- 242
PP P P K + ++ + Q K P + L G PH+ +
Sbjct: 354 EPPRTPPFPAKTFQVVPEIEFPPSLDLHQEIPQQEDQKKEVP--KRILDQNFGEPHIPSR 411
Query: 243 -------------VHRPLPPSRVIEELHRALATK-HRQDSFQGRESKGSPKKRLDVRLSR 288
+ PLP + ++E HRA + DSF S + L + +
Sbjct: 412 LPPLPLHIRIQQALTSPLPMTPILEGSHRAHSLLFENSDSFSEDSSTLGRTRSLPITIEM 471
Query: 289 TSSVERGKEREEAWSFDGALENKRTAA-------KESEENKENLIINSELKDDLLLYQDE 341
+ +E E+ + E T+ EE KE+ + + Y+DE
Sbjct: 472 LKVPDDEEEEEQTCPSTFSEEMTPTSVIPKLPQCLREEEEKES----DSDSEGPIQYRDE 527
Query: 342 EALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLS 401
E ++S S + +K+ LA+KL +RPS+ EL + N +P ++ EE EIR QI L
Sbjct: 528 EDEDESYQSALANKVKRKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLI 586
Query: 402 KRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFS 461
+RLSQRP EELE+RNIL+ +N+ Q E+REIK+RLTRKL+QRPTV EL RKIL RF+
Sbjct: 587 RRLSQRPTPEELEQRNILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKIL-RFN 645
Query: 462 DYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 518
+YVEV AQDYDRRADKPWT+L+ ADKAAIRKELNE+KS+EMEVH SKH TR+HRP
Sbjct: 646 EYVEVTDAQDYDRRADKPWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
Score = 90.9 bits (224), Expect = 3e-18
Identities = 82/281 (29%), Positives = 126/281 (44%), Gaps = 45/281 (16%)
Query: 14 SGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMAGRQGREELIKKG- 71
+G TPP +R SK + G+IFKPWKWRKKK ++K K+T+ LE+K++ R+ REEL+K+G
Sbjct: 24 AGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELVKRGV 83
Query: 72 LLEMMEQDAE-----------SKTCNPDGGPRS-----VQSEPPTPKS-----------E 104
LLE EQ E + P G RS V+ EP S +
Sbjct: 84 LLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEEDLKK 143
Query: 105 TLTSEDAQPGSPLATGTDQVSL------DKPLSSAAHLDDAAKMPSASSGEEADAGSLLP 158
L S +QP S + + V +PLSS+ + + SSG A ++
Sbjct: 144 RLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSG--GTARFIIS 201
Query: 159 TTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATLFQ-- 216
T+ ++ A A + S + + SV P+P LP P ++ T ++T Q
Sbjct: 202 TS--ITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHMVPAKQPP 259
Query: 217 ----ASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPSRVI 253
+ ++++P + L+ PLPP R I
Sbjct: 260 IPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGI 300
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 56.2 bits (134), Expect = 7e-08
Identities = 108/520 (20%), Positives = 196/520 (37%), Gaps = 72/520 (13%)
Query: 42 KKNEKLKQTTSALEKKMAGRQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPPTP 101
++ + ++ T EK+ +G+EE + G E E E P S + E +P
Sbjct: 462 EETQVTEEVTEEEEKEAKEEEGKEE--EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP 519
Query: 102 KSETLTS--EDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPT 159
E S E P A +V + S A ++A P A S E+ +A S
Sbjct: 520 VKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK-EEAKSPPEAKSPEKEEAKSPAEV 578
Query: 160 TN---------ELSQALAGADSLDSPPRPLE---RSVGQLPSP-------PLLPTPPPKA 200
+ E +++ A A S + P++ +S + SP P P KA
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKA 638
Query: 201 SSKTTKNVTGQATLF-----QASSMKSADPSLRGQLSTPTGSPHLTTVHRPLP------- 248
S T + +A S + A ++ + +P + P
Sbjct: 639 KSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698
Query: 249 ------PSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAW 302
P + + + + S E+K K + V+ S E+ K E+A
Sbjct: 699 KEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK-EEAKSPEKAKSPEKAK 757
Query: 303 SFDGALENKRTAAKE-----------------SEENKENLIINSELKDDLLLYQDEEALN 345
+ D +T AKE EE K S LK+D + E
Sbjct: 758 TLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK 817
Query: 346 DSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLS 405
+ + S P K +++ VK++ P K E E P+ EE+++ +++ + K+ +
Sbjct: 818 EEVKS---PVKEEEKPQEVKVKEPPKKAEEEKAPATPK--TEEKKDSKKE---EAPKKEA 869
Query: 406 QRPAVEELERRNILKQRNDQTE-QEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYV 464
+P VEE + + K + + E ++E E K+++ + P E+++ + +
Sbjct: 870 PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED---AKPKEKT 926
Query: 465 EVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEME 504
EVAK + D +A +P + A +K+ E K+ + E
Sbjct: 927 EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE 966
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 51.2 bits (121), Expect = 2e-06
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 19/172 (11%)
Query: 342 EALNDSIISGTLPRKCKKELLAVKLRNRPSKQELE-----------DRNIFPRRTDEERQ 390
E LN TLPR+ + L +++N PS++ELE + + R + ER
Sbjct: 109 EVLNSQETGPTLPRQNSQ--LPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERM 166
Query: 391 EIRQQIEMKLSKRLSQRPAVEE--LERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTV 448
E + +L + +R +E+ LER ++R ++ E++ER E ++RL R+
Sbjct: 167 ERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRER 226
Query: 449 DELRDRKILIRFSDYVEVAKAQDYDRRADKPWTR----LSAADKAAIRKELN 496
E ++R+ L R + + Q+ R W R SAA A++ LN
Sbjct: 227 QERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLN 278
Score = 32.7 bits (73), Expect = 0.82
Identities = 66/329 (20%), Positives = 118/329 (35%), Gaps = 53/329 (16%)
Query: 40 RKKKNEKLKQTTSALEKKMAGRQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPP 99
R+++ + ++ LE++ R+ +E+L + E +E + E + + P SV+
Sbjct: 224 RERQERQERERLERLERERQERERQEQLER----EQLEWERERRISSA-AAPASVE---- 274
Query: 100 TPKSETLTSEDA-QPG-----SPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADA 153
TP + L A +PG P T + Q + PL A P A A
Sbjct: 275 TPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPL--------APPPPPPLPPGPAQA 326
Query: 154 GSLLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPP--------KASSKTT 205
LP + PP P Q+P PP P PP + S+
Sbjct: 327 SVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDN 386
Query: 206 KNVTGQATLFQASSMKSAD-------PSLRGQLSTPTGSPHLTTVH----RPLPPSRVIE 254
+ +TG A + ++ PS + + S T PL S ++E
Sbjct: 387 RPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLME 446
Query: 255 EL------HRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGAL 308
E+ R +A K + +E KG + + + S TS+ E + W +
Sbjct: 447 EMSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASSTSTPE---PTRKPWERTNTM 503
Query: 309 ENKRT--AAKESEENKENLIINSELKDDL 335
++ ++ K ++ ++ D L
Sbjct: 504 NGSKSPVISRRDSPRKNQIVFDNRSYDSL 532
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 51.2 bits (121), Expect = 2e-06
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 19/172 (11%)
Query: 342 EALNDSIISGTLPRKCKKELLAVKLRNRPSKQELE-----------DRNIFPRRTDEERQ 390
E LN TLPR+ + L +++N PS++ELE + + R + ER
Sbjct: 109 EVLNSQETGPTLPRQNSQ--LPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERM 166
Query: 391 EIRQQIEMKLSKRLSQRPAVEE--LERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTV 448
E + +L + +R +E+ LER ++R ++ E++ER E ++RL R+
Sbjct: 167 ERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRER 226
Query: 449 DELRDRKILIRFSDYVEVAKAQDYDRRADKPWTR----LSAADKAAIRKELN 496
E ++R+ L R + + Q+ R W R SAA A++ LN
Sbjct: 227 QERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLN 278
Score = 32.0 bits (71), Expect = 1.4
Identities = 62/285 (21%), Positives = 104/285 (36%), Gaps = 48/285 (16%)
Query: 40 RKKKNEKLKQTTSALEKKMAGRQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPP 99
R+++ + ++ LE++ R+ +E+L + E +E + E + + P SV+
Sbjct: 224 RERQERQERERLERLERERQERERQEQLER----EQLEWERERRISSA-AAPASVE---- 274
Query: 100 TPKSETLTSEDA-QPG-----SPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADA 153
TP + L A +PG P T + Q + PL A P A A
Sbjct: 275 TPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPL--------APPPPPPLPPGPAQA 326
Query: 154 GSLLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPP--------KASSKTT 205
LP + PP P Q+P PP P PP + S+
Sbjct: 327 SVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDN 386
Query: 206 KNVTGQATLFQASSMKSAD-------PSLRGQLSTPTGSPHLTTVH----RPLPPSRVIE 254
+ +TG A + ++ PS + + S T PL S ++E
Sbjct: 387 RPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLME 446
Query: 255 EL------HRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVE 293
E+ R +A K + +E KG + + + S TS+ E
Sbjct: 447 EMSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASSTSTPE 491
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 50.4 bits (119), Expect = 4e-06
Identities = 47/229 (20%), Positives = 103/229 (44%), Gaps = 14/229 (6%)
Query: 293 ERGKEREEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGT 352
++ ER+ ++ R E +E + + E ++++ ++E SI++
Sbjct: 291 DQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEV---PEQEGEPSSIVNVP 347
Query: 353 LPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQ----RP 408
+++ L ++ N+ + L + + + E++E ++Q+ + KR+ Q R
Sbjct: 348 GESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRR 407
Query: 409 AVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAK 468
+EE +RR +R + EQ R + ++R +L +R +E R R + V +
Sbjct: 408 RLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR----AEEEKRRVER 463
Query: 469 AQDYDRR-ADKPWTRLSAADKAAIRKE--LNEYKSNEMEVHASSKHLTR 514
Q+Y RR ++ L + ++++ L E + EME H ++ L R
Sbjct: 464 EQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQR 512
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 48.5 bits (114), Expect = 1e-05
Identities = 96/448 (21%), Positives = 168/448 (37%), Gaps = 73/448 (16%)
Query: 91 PRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEE 150
P+ V SE P E A+P P G + S + A+ K P+ASS E
Sbjct: 368 PQKVGSEQKEPPEEAEPVAAAEPEVPENNGNN--SWPHNDTEIANSTPNPK-PAASSPET 424
Query: 151 ADAGSLLPTTNELSQALAGADSLDSPP------RPLERSVGQLPS----------PPLLP 194
AG T++ AD PP R +++V +L PP
Sbjct: 425 PSAGQQEAKTDQ-------ADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSK 477
Query: 195 TPP-PKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTTV-----HRPLP 248
TP P +SK + + Q + M L TPT +P + PL
Sbjct: 478 TPSSPCPASKVVRPLRTFLHTVQRNQM----------LMTPTSAPRSVMKSFIKRNTPLR 527
Query: 249 PSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGAL 308
+E R + ++++ Q R K KR + + ER ++ L
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK---------VL 578
Query: 309 ENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRN 368
+ + + EE K+ + D+ EE L + K KK+ A K+
Sbjct: 579 QARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE--------KAKKKAAAKKMEE 630
Query: 369 RPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQ 428
++++ E+ R +E +E R Q ++ K Q + E + + +QR + +
Sbjct: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 690
Query: 429 EERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDR-RADKPWTRLSAA- 486
+ERRE ++R + Q E R+++ E + ++ +R +A++ A
Sbjct: 691 QERREQERREQERREQ-----ERREQE-----RQLAEQERRREQERLQAERELQEREKAL 740
Query: 487 --DKAAIRKELNEYKSNEMEVHASSKHL 512
K +++EL E K E + + + L
Sbjct: 741 RLQKEQLQRELEEKKKKEEQQRLAERQL 768
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 47.8 bits (112), Expect = 2e-05
Identities = 88/415 (21%), Positives = 151/415 (36%), Gaps = 82/415 (19%)
Query: 20 PVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAGRQGREELIKKGLLEMMEQD 79
PVRR + + + + K K ++++NEK K A E+ + RQ + L +
Sbjct: 402 PVRRRPEASPVQK--KEKKDKERENEKEKSAL-ARERSLKKRQSLPASPRARLSASTASE 458
Query: 80 AESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDA 139
K+ P + P +P P P GT P ++A
Sbjct: 459 LSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTA----SPKGRVRRKEEA 514
Query: 140 AKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTP-PP 198
+ PSA+ G E + S +NE A +P P PSP PTP PP
Sbjct: 515 KESPSAA-GPEDKSQSKRRASNEKESA--------APASPA-------PSPAPSPTPAPP 558
Query: 199 KASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPSRVIEELHR 258
+ + T A L S P +P +T +P+ + EE R
Sbjct: 559 QKEQPPAETPTDAAVL----------------TSPPAPAPPVTP-SKPMAGTTDREEATR 601
Query: 259 ALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKES 318
LA K RQ RE + ++ ++ R +R +E + A + E + A +
Sbjct: 602 LLAEKRRQ----AREQREREEQERRLQAERD---KRMREEQLAREAEARAEREAEARRRE 654
Query: 319 EENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDR 378
E+ + + + L Q EEA + R +Q LE
Sbjct: 655 EQEAREKAQAEQEEQERLQKQKEEA-------------------EARSREEAERQRLERE 695
Query: 379 NIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERRE 433
F ++ ++ERQE R+++E E+ +R + ++ ++++ +E
Sbjct: 696 KHFQQQ-EQERQERRKRLE--------------EIMKRTRKSEVSETKQKQDSKE 735
Score = 36.2 bits (82), Expect = 0.074
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 33/243 (13%)
Query: 86 NPDGGPRSVQSEPPTPKSETL--TSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMP 143
+P+G P S PP P S + T D P AT + Q+ L+ P S + + P
Sbjct: 28 SPEGDP----SPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLE-PESPSGQVGPRPAPP 82
Query: 144 SASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLP---TPPPKA 200
S ++A S PT A+ D+ RP RS PSP +P +PP K
Sbjct: 83 QEES-PSSEAKSRGPTP----PAMGPRDA-----RPPRRS--SQPSPTAVPASDSPPTKQ 130
Query: 201 SSKTT--KNVTGQATLFQASSMKSADPSL---RGQLSTPTGSPHLTTVHRPLPPSRVIEE 255
K ++ + + + +A ++ + + + L R L R+ E
Sbjct: 131 EVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAE 190
Query: 256 LHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAA 315
RA A + RQ R+ K+R + + R+ + R++ WS+ GAL +
Sbjct: 191 QRRA-ALEERQ-----RQKLEKNKERYEAAIQRSVKKTWAEIRQQRWSWAGALHHSSPGH 244
Query: 316 KES 318
K S
Sbjct: 245 KTS 247
Score = 30.0 bits (66), Expect = 5.3
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 18/116 (15%)
Query: 370 PSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAV--EELERRNILKQRNDQTE 427
P+KQE++ ER ++ ++ + +K L+ + AV E+ E+ L+++ Q +
Sbjct: 127 PTKQEVKKAG--------ERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREK--QLQ 176
Query: 428 QEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRL 483
+ RR +QRL K QR E R R+ L + + E A R K W +
Sbjct: 177 ERRRRLEEQRL--KAEQRRAALEERQRQKLEKNKERYEAA----IQRSVKKTWAEI 226
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo
sapiens]
Length = 2365
Score = 47.4 bits (111), Expect = 3e-05
Identities = 81/385 (21%), Positives = 143/385 (37%), Gaps = 41/385 (10%)
Query: 78 QDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGT---DQVSLDKPLSSAA 134
+D +C PR+ S P + T+ AQ +P A+ T ++ + D P +S A
Sbjct: 523 RDNPRTSCAQRDNPRA--SSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCA 580
Query: 135 HLDDAAKMPSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLP 194
D+ P ASS A + PTT+ + A SP R+ P
Sbjct: 581 QRDN----PRASSPNRATRDN--PTTSCAQRDNPRASRTSSP----NRATRDNPRTSCAQ 630
Query: 195 TPPPKASS--KTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPSRV 252
P+ASS +TT+ + + + + +++ P+ Q P S L R PSR
Sbjct: 631 RDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRT 690
Query: 253 IEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKR 312
I++ + + R D SP + RTS R R + + +N R
Sbjct: 691 IQQENPRTSCAQRDD-----PRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPR 745
Query: 313 TAAKESEE----------NKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELL 362
T+ + + +ENL + +D+ A D+ + R +
Sbjct: 746 TSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASS 805
Query: 363 AVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQR 422
++ + + + +NI PR + ++ + +KR + RP + +R +
Sbjct: 806 PIRATQQDNPRTCIQQNI-PRSSSTQQDNPK----TSCTKRDNLRPTCTQRDRTQSFSFQ 860
Query: 423 NDQTEQEERREIKQRLTRKLNQRPT 447
D Q T+K N RP+
Sbjct: 861 RDNPGTSS----SQCCTQKENLRPS 881
>gi|148727255 microtubule associated serine/threonine kinase family
member 4 isoform a [Homo sapiens]
Length = 2434
Score = 47.4 bits (111), Expect = 3e-05
Identities = 83/309 (26%), Positives = 126/309 (40%), Gaps = 58/309 (18%)
Query: 14 SGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAGRQGREELIKKGLL 73
+ I+T P RRNS + + R K + KK E L++ S L KK+A +Q L
Sbjct: 1042 TSIKTGPARRNSYKSRMVRRSK----KSKKKESLERRRS-LFKKLA-KQPSPLLHTSRSF 1095
Query: 74 EMMEQDAESKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSA 133
+ + S P S+ PTP S + P P T + Q S P SSA
Sbjct: 1096 SCLNRSLSSGESLPGSPTHSLSPRSPTP------SYRSTPDFPSGTNSSQSS--SPSSSA 1147
Query: 134 AHLDDAAKMPSASSGEEADAGSLLPTT-NELSQALAGA--------DSLDSPPRPLERSV 184
P++ +G +G + P+T + L+ L G + + P PL R+
Sbjct: 1148 ---------PNSPAG----SGHIRPSTLHGLAPKLGGQRYRSGRRKSAGNIPLSPLART- 1193
Query: 185 GQLPSPPLLPTPPPKASSKTTKNVTGQATLFQASSMKSADPS------LRGQLSTPTGSP 238
PSP PT P ++ S + G + + QA K P +R + + P SP
Sbjct: 1194 ---PSPTPQPTSPQRSPSPLLGHSLGNSKIAQAFPSKMHSPPTIVRHIVRPKSAEPPRSP 1250
Query: 239 HLTTV--HRPLPPSRVIEELH---RALATKHRQDSFQGRES-KGSPKKRLDVR------L 286
L V L PS ++ H R + + Q+ Q +S + +P + LD L
Sbjct: 1251 LLKRVQSEEKLSPSYGSDKKHLCSRKHSLEVTQEEVQREQSQREAPLQSLDENVCDVPPL 1310
Query: 287 SRTSSVERG 295
SR VE+G
Sbjct: 1311 SRARPVEQG 1319
Score = 30.0 bits (66), Expect = 5.3
Identities = 50/224 (22%), Positives = 85/224 (37%), Gaps = 37/224 (16%)
Query: 83 KTCNPDGGPRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKM 142
KT + DG ++ PP + +L S G P +V A L +
Sbjct: 1852 KTNHKDGPG---EARPPPRDNSSLHSA----GIPCEKELGKVRRGVEPKPEALLARRSLQ 1904
Query: 143 PSASSGEEADAGSLLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPL----LPTPPP 198
P E+++ S P+ + GA + +PL+R +P PPL L +P
Sbjct: 1905 PPGIESEKSEKLSSFPSLQK-----DGAKEPERKEQPLQRHPSSIPPPPLTAKDLSSPAA 1959
Query: 199 KASSKTTKNVTGQATLFQASSMKSADPSLRGQ-LSTPTGSPHLTTVHRPLP--------- 248
+ + + +G+ + +A+PS Q P + ++ H+P P
Sbjct: 1960 RQHCSSPSHASGRE---PGAKPSTAEPSSSPQDPPKPVAAHSESSSHKPRPGPDPGPPKT 2016
Query: 249 --PSRVIEELHRAL-ATKHRQDSFQ-----GRESKGSPKKRLDV 284
P R + ++ ATK ++ + Q RE KG K DV
Sbjct: 2017 KHPDRSLSSQKPSVGATKGKEPATQSLGGSSREGKGHSKSGPDV 2060
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 47.4 bits (111), Expect = 3e-05
Identities = 98/452 (21%), Positives = 170/452 (37%), Gaps = 77/452 (17%)
Query: 91 PRSVQSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEE 150
P+ V SE P E A+P P G + S + A+ K P+ASS E
Sbjct: 368 PQKVGSEQKEPPEEAEPVAAAEPEVPENNGNN--SWPHNDTEIANSTPNPK-PAASSPET 424
Query: 151 ADAGSLLPTTNELSQALAGADSLDSPP------RPLERSVGQLPS----------PPLLP 194
AG T++ AD PP R +++V +L PP
Sbjct: 425 PSAGQQEAKTDQ-------ADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSK 477
Query: 195 TPP-PKASSKTTKNVTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTT---VHRPLPP- 249
TP P +SK + + Q + M L TPT +P + R P
Sbjct: 478 TPSSPCPASKVVRPLRTFLHTVQRNQM----------LMTPTSAPRSVMKSFIKRNTPLR 527
Query: 250 -----SRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSF 304
S V +E R + ++++ Q R K KR + + ER ++
Sbjct: 528 MDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK------- 580
Query: 305 DGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAV 364
L+ + + EE K+ + D+ EE L + K KK+ A
Sbjct: 581 --VLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE--------KAKKKAAAK 630
Query: 365 KLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRND 424
K+ ++++ E+ R +E +E R Q ++ K Q + E + + +QR
Sbjct: 631 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 690
Query: 425 QTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDR-RADKPWTRL 483
+ ++ERRE ++R + Q E R+++ E + ++ +R +A++
Sbjct: 691 ERREQERREQERREQERREQ-----ERREQE-----RQLAEQERRREQERLQAERELQER 740
Query: 484 SAA---DKAAIRKELNEYKSNEMEVHASSKHL 512
A K +++EL E K E + + + L
Sbjct: 741 EKALRLQKEQLQRELEEKKKKEEQQRLAERQL 772
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 47.0 bits (110), Expect = 4e-05
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 37/188 (19%)
Query: 270 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINS 329
+G++ K KKR ERGKERE E +R +E E K
Sbjct: 58 RGKKEKKKRKKR-----------ERGKERERKRK---EREKQRKERREKERRKR------ 97
Query: 330 ELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEER 389
+ E+ + G RK KKE K R R +KQ E R RR + R
Sbjct: 98 ---------KKEKKKRERKQRGRRERKKKKER---KERERENKQRRE-RKRKKRRKKKRR 144
Query: 390 QEIRQQIE--MKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPT 447
+E +++ E + KR ++ E +R K+R + E++ERRE K+ RK +R
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE--RKKERRKK 202
Query: 448 VDELRDRK 455
+ +DRK
Sbjct: 203 KERKKDRK 210
Score = 37.7 bits (86), Expect = 0.025
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 367 RNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQT 426
R K+E +R R ++ER+ R + E K K+ +R E +R+ KQR ++
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKK-RERGKERERKRKEREKQRKERR 90
Query: 427 EQEERREIKQRLTRKLNQR 445
E+E R+ K++ R+ QR
Sbjct: 91 EKERRKRKKEKKKRERKQR 109
Score = 36.6 bits (83), Expect = 0.057
Identities = 33/156 (21%), Positives = 61/156 (39%)
Query: 355 RKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELE 414
R+ +KE + + K++ +R R +ER++ R++ K ++ + E +
Sbjct: 48 REREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK 107
Query: 415 RRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDR 474
+R +++ + +E RE KQR RK +R ++RK K + +
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
Query: 475 RADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSK 510
R K K RKE E K + K
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Score = 34.3 bits (77), Expect = 0.28
Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Query: 358 KKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRN 417
KKE + R R ++E + + +++E ++ E K +R QR E ERR
Sbjct: 37 KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRK 96
Query: 418 ILKQRND-QTEQEERREIKQRLTRKLNQRPTVDELRDRK 455
K++ + +Q RRE K++ RK +R + R+RK
Sbjct: 97 RKKEKKKRERKQRGRRERKKKKERKEREREN-KQRRERK 134
Score = 33.5 bits (75), Expect = 0.48
Identities = 33/168 (19%), Positives = 76/168 (45%), Gaps = 4/168 (2%)
Query: 351 GTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAV 410
G +K +K+ K R R K+ + R R ++ER++ +++ + + K+ +R
Sbjct: 59 GKKEKKKRKKRERGKERERKRKEREKQRK---ERREKERRKRKKEKKKRERKQRGRRERK 115
Query: 411 EELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQ 470
++ ER+ ++ N Q + +R++ +++ RK +R R+RK R + E + +
Sbjct: 116 KKKERKE-RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174
Query: 471 DYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 518
+ R + + K +KE + K + + + ++ RP
Sbjct: 175 NRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRP 222
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 46.6 bits (109), Expect = 5e-05
Identities = 62/260 (23%), Positives = 109/260 (41%), Gaps = 25/260 (9%)
Query: 253 IEELHRALATKHRQDSFQGRESKGSPK--KRLDVRLSRTSSVERGKEREEAWSFDGALEN 310
++ L L K R+ +E K K K D R S+ S+E G+ R+ + N
Sbjct: 10 VKTLDEILQEKKRRKE---QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI--TIRN 64
Query: 311 KRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRP 370
++S E++ E D L + ++ + K K++ A R +
Sbjct: 65 SPYRREDSMEDR------GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHA---RVKE 115
Query: 371 SKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLS--QRPAVEELERR--NILKQRNDQT 426
++E E R D+ R+E +Q ++++ S +R +E+LER+ K R Q
Sbjct: 116 KEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQK 175
Query: 427 EQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADK-PWTRLSA 485
EQ E++E ++R + +R E+ +R DY + KA + R + P R
Sbjct: 176 EQREQKERERRAEERRKEREARREVSAHHRTMR-EDYSDKVKASHWSRSPPRPPRERFEL 234
Query: 486 ADKAAIRKELNEYKSNEMEV 505
D RK + E K E ++
Sbjct: 235 GDG---RKPVKEEKMEERDL 251
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 45.8 bits (107), Expect = 9e-05
Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 7/184 (3%)
Query: 266 QDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENL 325
++ + RE + ++ + R ER +ERE + + KR ++ E+ E
Sbjct: 385 REKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERR 444
Query: 326 IINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRT 385
+ +L++ YQ E N I R+ +KE + R R +E + F
Sbjct: 445 KLERKLREKEAAYQ-ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY 503
Query: 386 DEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQR 445
D++R + + L KRL R E + +R+ + E+EE EI+QRL + +
Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEAD------ERDRKREKEELEEIRQRLLAEGHPD 557
Query: 446 PTVD 449
P +
Sbjct: 558 PDAE 561
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/167 (27%), Positives = 71/167 (42%), Gaps = 12/167 (7%)
Query: 285 RLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEAL 344
RL ER K RE + E +R AKE++ KE L + +DD Y+ AL
Sbjct: 460 RLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGS-AL 518
Query: 345 NDSIISGTLPRKCKKELLAVKLRNRPSKQELED--RNIFPRR---TDEERQEIRQQIEMK 399
+ R +KE+ A + + K+ELE+ + + D E Q + Q+ E +
Sbjct: 519 QKRL------RDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR 572
Query: 400 LSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRP 446
++ Q P EE E K+ + EE E +Q+ K RP
Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRP 619
Score = 42.4 bits (98), Expect = 0.001
Identities = 58/263 (22%), Positives = 105/263 (39%), Gaps = 11/263 (4%)
Query: 244 HRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVR---LSRTSSVERGKEREE 300
H+ L + +E R K R++ + RE + ++R R R ER +ERE
Sbjct: 288 HKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERER 347
Query: 301 AWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQ---DEEALNDSIISGTLPRKC 357
D E R +E + +++ + KD + D E + R+
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERER 407
Query: 358 KKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKR---LSQRPAVEELE 414
++E + R R ++E E R DEE R+++E KL ++ +R E+
Sbjct: 408 EREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467
Query: 415 RRNILKQRNDQTEQEE--RREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDY 472
R ++ + E+EE RRE+ + R D+ RD R S + + ++
Sbjct: 468 ERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREK 527
Query: 473 DRRADKPWTRLSAADKAAIRKEL 495
+ AD+ + + IR+ L
Sbjct: 528 EMEADERDRKREKEELEEIRQRL 550
Score = 42.4 bits (98), Expect = 0.001
Identities = 53/236 (22%), Positives = 94/236 (39%), Gaps = 36/236 (15%)
Query: 263 KHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENK 322
K RQ+ + R + ++R R R ER +ERE+ + E R + E ++
Sbjct: 300 KERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR 359
Query: 323 ENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 382
+ + E D +D E +D RN+ + E
Sbjct: 360 DR---DRERDRD----RDRERSSD--------------------RNKDRSRSREKSRDRE 392
Query: 383 RRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 442
R + ER+ R++ + +R +R E ER ++ D+ E EE +++L RKL
Sbjct: 393 REREREREREREREREREREREREREREREREREK--DKKRDREEDEEDAYERRKLERKL 450
Query: 443 NQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEY 498
++ + R + IR E K ++Y++ A++ R K A K L E+
Sbjct: 451 REKEAAYQERLKNWEIR-----ERKKTREYEKEAEREEERRREMAKEA--KRLKEF 499
Score = 36.2 bits (82), Expect = 0.074
Identities = 31/148 (20%), Positives = 74/148 (50%), Gaps = 12/148 (8%)
Query: 354 PRKCKKELLAVKL----RNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPA 409
P K+++ A+++ R+ S++ + R+ + +E+ ++ +++ E++ +R +R
Sbjct: 257 PLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERER 316
Query: 410 VEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKA 469
E ERR ++R + E+E+ +E ++ R ++ T + RDR E +
Sbjct: 317 ERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRD--------RERDRD 368
Query: 470 QDYDRRADKPWTRLSAADKAAIRKELNE 497
+D +R +D+ R + +K+ R+ E
Sbjct: 369 RDRERSSDRNKDRSRSREKSRDRERERE 396
>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
Length = 1113
Score = 45.8 bits (107), Expect = 9e-05
Identities = 73/276 (26%), Positives = 120/276 (43%), Gaps = 45/276 (16%)
Query: 176 PPRPLERSVGQLPSPPLLPTPPPKAS--SKTTKNVTGQ--ATLFQASSMKSADPSLRGQL 231
PP P R G L P LP P P + K+T+ + GQ A+L QA++ G+L
Sbjct: 547 PPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATF--------GEL 598
Query: 232 STP--TGSPHLTTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRT 289
S P GSP+ V R P+ + +E L + R S +LD+ R
Sbjct: 599 SGPLKPGSPYRPPVPRAPDPAYIYDEF---LQQRRRLVS------------KLDLEERR- 642
Query: 290 SSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSII 349
R + +E+ + +D L++ + E EE + +L +E + L L E L +
Sbjct: 643 ----RREAQEKGYYYD--LDDSYDESDE-EEVRAHLRCVAE-QPPLKLDTSSEKLEFLQL 694
Query: 350 SGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKL---SKRLSQ 406
G ++ K+EL+A K R R ++ L +R+ P +RQ ++ + ++
Sbjct: 695 FGLTTQQQKEELVAQKRRKR--RRMLRERSPSPPTIQSKRQTPSPRLALSTRYSPDEMNN 752
Query: 407 RPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 442
P E E++ L N E+R+ K+RL L
Sbjct: 753 SPNFE--EKKKFLTIFNLTHISAEKRKDKERLVEML 786
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 386 DEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQR 445
DEE + R++ + +R + R +E ER K+R + E+E +E ++ L R+ QR
Sbjct: 230 DEELRREREREREREREREADREREKERERERE-KEREQEKEREREKERERELERQREQR 288
Query: 446 PTVDELRDRKIL 457
EL K L
Sbjct: 289 AREKELLAAKAL 300
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 45.8 bits (107), Expect = 9e-05
Identities = 73/276 (26%), Positives = 120/276 (43%), Gaps = 45/276 (16%)
Query: 176 PPRPLERSVGQLPSPPLLPTPPPKAS--SKTTKNVTGQ--ATLFQASSMKSADPSLRGQL 231
PP P R G L P LP P P + K+T+ + GQ A+L QA++ G+L
Sbjct: 651 PPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATF--------GEL 702
Query: 232 STP--TGSPHLTTVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRT 289
S P GSP+ V R P+ + +E L + R S +LD+ R
Sbjct: 703 SGPLKPGSPYRPPVPRAPDPAYIYDEF---LQQRRRLVS------------KLDLEERR- 746
Query: 290 SSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSII 349
R + +E+ + +D L++ + E EE + +L +E + L L E L +
Sbjct: 747 ----RREAQEKGYYYD--LDDSYDESDE-EEVRAHLRCVAE-QPPLKLDTSSEKLEFLQL 798
Query: 350 SGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKL---SKRLSQ 406
G ++ K+EL+A K R R ++ L +R+ P +RQ ++ + ++
Sbjct: 799 FGLTTQQQKEELVAQKRRKR--RRMLRERSPSPPTIQSKRQTPSPRLALSTRYSPDEMNN 856
Query: 407 RPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 442
P E E++ L N E+R+ K+RL L
Sbjct: 857 SPNFE--EKKKFLTIFNLTHISAEKRKDKERLVEML 890
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 386 DEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQR 445
DEE + R++ + +R + R +E ER K+R + E+E +E ++ L R+ QR
Sbjct: 334 DEELRREREREREREREREADREREKERERERE-KEREQEKEREREKERERELERQREQR 392
Query: 446 PTVDELRDRKIL 457
EL K L
Sbjct: 393 AREKELLAAKAL 404
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 45.4 bits (106), Expect = 1e-04
Identities = 42/183 (22%), Positives = 86/183 (46%), Gaps = 10/183 (5%)
Query: 263 KHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENK 322
+H Q+ + + + ++R + L R ++ E +R + +E +
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Query: 323 ENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 382
E L L+ + L +++E + + L R+ +K L + R +++ E R+
Sbjct: 526 ERL--QQRLRSEQQLRREQEERREQL----LKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 383 RRTDEERQE-IRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRK 441
+R +E RQ+ ++++ E +L +RL +R VE LE+ +QR + E EE R +Q+L +
Sbjct: 580 KREEERRQQRLKREQEERLEQRL-KREEVERLEQEERREQRLKREEPEEER--RQQLLKS 636
Query: 442 LNQ 444
Q
Sbjct: 637 EEQ 639
Score = 43.9 bits (102), Expect = 4e-04
Identities = 37/192 (19%), Positives = 82/192 (42%), Gaps = 9/192 (4%)
Query: 263 KHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKE--------REEAWSFDGALENKRTA 314
+ +++ + R + ++RL RL + R +E REE + +R
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568
Query: 315 AKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQE 374
++ E + L E + L + EE L + + R ++E +L+ ++E
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
Query: 375 LEDRNIFPRRTDEERQ-EIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERRE 433
+ + +E RQ ++R++ + + +RL + E LE+R + ++ EQE E
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
Query: 434 IKQRLTRKLNQR 445
+++ ++ R
Sbjct: 689 EQEQARERIKSR 700
Score = 41.6 bits (96), Expect = 0.002
Identities = 48/252 (19%), Positives = 108/252 (42%), Gaps = 35/252 (13%)
Query: 254 EELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRT 313
E+L R K R+ + + + ++ + +L R +R +ERE + + L+ ++
Sbjct: 1151 EQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210
Query: 314 AAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQ 373
+ +E++ S+LK ++ ++ + + ++L +LR+R S+Q
Sbjct: 1211 KQRYRDEDQR-----SDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQ 1265
Query: 374 ELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERRE 433
+L+ E+++ R+Q + +R P E+LER EE++E
Sbjct: 1266 DLQ------HLLGEQQERDREQERRRWQQRDRHFPEEEQLER-------------EEQKE 1306
Query: 434 IKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRK 493
K+R + ++ + E R+ K + Q+ DR+ + L ++ +R+
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEK-----------RRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 494 ELNEYKSNEMEV 505
+ + K E E+
Sbjct: 1356 QERDRKFREEEL 1367
Score = 41.2 bits (95), Expect = 0.002
Identities = 47/243 (19%), Positives = 104/243 (42%), Gaps = 26/243 (10%)
Query: 263 KHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENK 322
+ +Q+ + +E + + R + R + R +E E E + +E E +
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERR-------EQQLRREQEEERRE 374
Query: 323 ENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 382
+ L +L+ + L ++++ + ++ ++E + + +Q+L
Sbjct: 375 QQLRREQQLRREQQLRREQQLRRE--------QQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 383 RRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 442
R +EER E + + E R QR E+ ERR+ LK R ++TE+ E+ KQ+L
Sbjct: 427 REQEEERHEQKHEQE-----RREQRLKREQEERRDWLK-REEETERHEQERRKQQL---- 476
Query: 443 NQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNE 502
+R +E R+R + + + E + ++ R ++ R + + L + +E
Sbjct: 477 -KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 503 MEV 505
++
Sbjct: 536 QQL 538
Score = 40.4 bits (93), Expect = 0.004
Identities = 43/222 (19%), Positives = 98/222 (44%), Gaps = 16/222 (7%)
Query: 254 EELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKE----------REEAWS 303
EE + +Q+ + ++ + ++R + +L R ER ++ RE+
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 304 FDGALENKRTAAKESEENKEN-LIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELL 362
+ L ++ +E + +E L +L+ + L ++++ + + + ++
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
Query: 363 AVKLRNRPSKQELEDRNIFPRRTDE----ERQEIRQQIEMKLSKRLSQR-PAVEELERRN 417
+ R + K+E E+R + +R +E E++ +QQ++ + +R +EE ERR
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 418 ILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIR 459
++R Q +E+ +QRL R+ + LR + L R
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Score = 40.4 bits (93), Expect = 0.004
Identities = 49/210 (23%), Positives = 88/210 (41%), Gaps = 15/210 (7%)
Query: 254 EELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRT 313
EE + L Q+ + ++ + ++R + RL R ER ++R + + E +
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE-- 684
Query: 314 AAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKC----KKELLAVKLRNR 369
A+E +E I + K L + +A + S PRK +++ K R R
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR--PRKQEGQRRRQEQEEKRRRR 742
Query: 370 PSKQELEDRNIFPRRTDEERQEI----RQQIEMKLSK---RLSQRPAVEELERRNILKQR 422
S+ + ++ R+ EE Q + Q E K + RLS RP + E R + +
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
Query: 423 NDQTEQEERREIKQRLTRKLNQRPTVDELR 452
Q EQ E +++ R+ +R EL+
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQ 832
Score = 40.4 bits (93), Expect = 0.004
Identities = 50/242 (20%), Positives = 92/242 (38%), Gaps = 31/242 (12%)
Query: 270 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSF-----DGALENKRTAAKESEENKEN 324
Q RE K ++ L + ER K R + W D + + +E E +
Sbjct: 984 QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL 1043
Query: 325 LIINSELKDDLLLYQDEEAL----NDSIISGTLPRKCKKELLAVK-----LRNRPSKQEL 375
+ +++ L Q+EE L ++ L R+ +KE + LR P K+
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103
Query: 376 EDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIK 435
++R R +E +QE Q + + KR Q + E + ++ +E + +
Sbjct: 1104 QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR 1163
Query: 436 QRLTRKLNQRPTVD--------ELRDRKILIRFSDYVEVAKAQ---------DYDRRADK 478
Q L R+ + + E ++++ R Y E + Q D D+R+D
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDL 1223
Query: 479 PW 480
W
Sbjct: 1224 KW 1225
Score = 40.0 bits (92), Expect = 0.005
Identities = 50/258 (19%), Positives = 109/258 (42%), Gaps = 35/258 (13%)
Query: 265 RQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKEN 324
R++ + + K ++RL+ RL R VER ++ E +R +E EE +
Sbjct: 581 REEERRQQRLKREQEERLEQRLKR-EEVERLEQEER--------REQRLKREEPEEERRQ 631
Query: 325 LIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRR 384
++ SE +++ Q + L R+ ++E L +L K+E E+
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERR-EQRLKREEEEERLEQRL-----KREHEEERREQEL 685
Query: 385 TDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQ 444
+EE+++ R++I+ ++ K Q + + + + + Q Q R+E +++ R+ ++
Sbjct: 686 AEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
Query: 445 RPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKA-------AIRKELNE 497
+E R + + Q+ ++R D W + A +K+ + R L E
Sbjct: 746 LQWQEEERAHR------------QQQEEEQRRDFTW-QWQAEEKSERGRQRLSARPPLRE 792
Query: 498 YKSNEMEVHASSKHLTRF 515
+ ++ + RF
Sbjct: 793 QRERQLRAEERQQREQRF 810
Score = 39.7 bits (91), Expect = 0.007
Identities = 47/211 (22%), Positives = 97/211 (45%), Gaps = 35/211 (16%)
Query: 254 EELHRALATKHRQDSFQGRESKGSP-----KKRLDVRLSRTSSVERGKEREEAWSFDGAL 308
+E A + + S +G E++ P ++R + L R E+ ++R E
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRE-------- 232
Query: 309 ENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRN 368
++ + EE KE K + +L ++EE L + + ++E L
Sbjct: 233 --RQDRVFQEEEEKE------WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL------ 278
Query: 369 RPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQ 428
++LE + + R +EE+Q+ R + E +L ++ + ++ ERR ++R Q E+
Sbjct: 279 ----RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 429 EE---RREIKQRLTRKLNQRPTVDELRDRKI 456
E RRE ++R ++L +R +E R++++
Sbjct: 335 REQQLRREQEERREQQL-RREQEEERREQQL 364
Score = 39.3 bits (90), Expect = 0.009
Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 18/196 (9%)
Query: 254 EELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGAL----E 309
++L R + Q + ++ + + R + +L R ER +++ E + L E
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 310 NKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNR 369
+R K EE + + K L Q+EE + R+ ++E +LR
Sbjct: 453 ERRDWLKREEETERHE--QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR-- 508
Query: 370 PSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQE 429
+E E+R + EE + ++Q++ + R Q E R +LK+ ++ ++
Sbjct: 509 ---REQEERREQRLKRQEEEERLQQRLRSEQQLRREQ-----EERREQLLKREEEKRLEQ 560
Query: 430 ERREIKQRLTRKLNQR 445
ERRE QRL R+ +R
Sbjct: 561 ERRE--QRLKREQEER 574
Score = 38.9 bits (89), Expect = 0.011
Identities = 42/181 (23%), Positives = 78/181 (43%), Gaps = 25/181 (13%)
Query: 359 KELLAVKLRNRPSKQELEDRNIFPRRTDEE----RQEIRQQIEMKLSKRLSQRPAVEELE 414
KE L R ++ E R+ R+ +EE R++ RQ+ E +L++ Q E LE
Sbjct: 106 KESLLQDRRQEEDQRRFEPRD---RQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLE 162
Query: 415 RRN-------ILKQRNDQTEQEERREIKQRLT----RKLNQRPTVDELRDRKILI----- 458
+R+ + +QR + E+EERR +++L + + P ++LR R++L
Sbjct: 163 QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKG 222
Query: 459 RFSDYVEVAKAQD--YDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFH 516
R + + QD + +K W + + K E + E+ + L +
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 517 R 517
R
Sbjct: 283 R 283
Score = 38.9 bits (89), Expect = 0.011
Identities = 45/224 (20%), Positives = 91/224 (40%), Gaps = 21/224 (9%)
Query: 294 RGKEREEAWSFDGALENKRTAA-KESEENKENLIINSELKDDLLLYQDEEALNDSIISGT 352
R +E+E + + L+ + +E E + + + D L Q EE L G
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL-----LGE 976
Query: 353 LPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEE 412
P K +++ K R Q+ E++ + R RQE +Q K + + + E
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 413 LERRNILKQRNDQTEQE------------ERREIKQRLTRKLNQRPTVDELRDRKILIRF 460
+ L++R Q +E E RE ++R + R + ++ + L+R
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR- 1095
Query: 461 SDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEME 504
+ E + Q+ +R+ + L ++ +R+E + + E+E
Sbjct: 1096 -EEPEKRRRQERERQC-REEEELQQEEEQLLREEREKRRRQELE 1137
Score = 38.5 bits (88), Expect = 0.015
Identities = 53/217 (24%), Positives = 95/217 (43%), Gaps = 41/217 (18%)
Query: 254 EELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRT 313
EE H KH Q+ + R + ++R ++ + + R++ D E +
Sbjct: 431 EERHEQ---KHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 314 AAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQ 373
K EE + E ++ L + EE L R+ ++E L +LR S+Q
Sbjct: 488 WLKLEEEERRE---QQERREQQLRREQEERREQR-----LKRQEEEERLQQRLR---SEQ 536
Query: 374 ELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERR----------NILKQRN 423
+L RR EER+E Q ++ + KRL Q E E+R +LK+
Sbjct: 537 QL-------RREQEERRE--QLLKREEEKRLEQ----ERREQRLKREQEERRDQLLKREE 583
Query: 424 DQTEQEERRE----IKQRLTRKLNQRPTVDELRDRKI 456
++ +Q +RE ++QRL R+ +R +E R++++
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Score = 38.1 bits (87), Expect = 0.020
Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 12/196 (6%)
Query: 270 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAW--SFDGALENKRTAAKESEENKENL-- 325
+GRE K ++ R+ + + ++RE + E + +E +E +E L
Sbjct: 221 KGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK 280
Query: 326 IINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQEL-----EDRNI 380
+ EL+ + Q+EE + R+ ++E + R +QE E R
Sbjct: 281 LERQELRRER---QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337
Query: 381 FPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTR 440
RR EER+E + + E + +R Q +E ERR +R Q +E++ +Q+L R
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397
Query: 441 KLNQRPTVDELRDRKI 456
+ R R++++
Sbjct: 398 EQQLRREQQLRREQQL 413
Score = 37.7 bits (86), Expect = 0.025
Identities = 48/206 (23%), Positives = 94/206 (45%), Gaps = 24/206 (11%)
Query: 254 EELHRALATKHRQDSFQGRES-KGSPKKRLDVRLSRTSSVERGKE--REEAWSFDGALEN 310
++L R + R+ + + + + R + +L R + R ++ RE+ + L
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 311 KRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRP 370
++ +E EE + E ++ L + EE + L R+ + E + R +
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRD------WLKREEETERHEQERRKQQ 475
Query: 371 SK--QELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQ 428
K QE E R + + +EER+E +++ E +L + E+ ERR +QR + E+
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRR--------EQEERR---EQRLKRQEE 524
Query: 429 EERREIKQRLTRKLNQRPTVDELRDR 454
EER ++QRL + R +E R++
Sbjct: 525 EER--LQQRLRSEQQLRREQEERREQ 548
Score = 37.0 bits (84), Expect = 0.043
Identities = 51/266 (19%), Positives = 106/266 (39%), Gaps = 36/266 (13%)
Query: 250 SRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALE 309
S+V + + RQ+ + R + S + + + E + R+ W +
Sbjct: 717 SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ---- 772
Query: 310 NKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNR 369
A ++SE ++ L L++ Q E L +E + R
Sbjct: 773 ----AEEKSERGRQRLSARPPLRE-----QRERQLR------------AEERQQREQRFL 811
Query: 370 PSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEE-----LERRNILKQRND 424
P ++E E R R ++E Q + ++ +++ +R Q E+ ERR +QR D
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD 871
Query: 425 QTEQEERREIKQRLTRKLNQRPTVDE-LRDRKILIRFSDYVEVAKAQDYDRRAD-----K 478
Q + + E ++R L +P + E LR + L++ + + ++ RR + +
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 479 PWTRLSAADKAAIRKELNEYKSNEME 504
+L ++ +R+E + + E E
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERE 957
Score = 35.4 bits (80), Expect = 0.13
Identities = 42/204 (20%), Positives = 89/204 (43%), Gaps = 23/204 (11%)
Query: 263 KHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENK 322
K Q+ Q R + K R + +L + + E+ + +E + LE ++ + E+
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER---YRKILEEEQLRPEREEQQL 1764
Query: 323 ENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 382
+ + +++ L Q+ E + S RK ++E +QE E++ + P
Sbjct: 1765 RRQERDRKFREEEQLRQERE--EQQLRSQESDRKFREE--------EQLRQEREEQQLRP 1814
Query: 383 RRTD------EERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQ 436
++ D EE+ ++ +Q + +R Q A E+ + ++ + QEE ++ +Q
Sbjct: 1815 QQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ 1874
Query: 437 RLTRKLNQ----RPTVDELRDRKI 456
RKL + R +E R R++
Sbjct: 1875 ERERKLREEHIRRQQKEEQRHRQV 1898
Score = 34.7 bits (78), Expect = 0.22
Identities = 56/278 (20%), Positives = 118/278 (42%), Gaps = 39/278 (14%)
Query: 248 PPSRVIEELH-RALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDG 306
PP R E RA + R+ F E + ++R R R ++ +E E+ +
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ--RREREKELQFLEEEEQLQRRER 845
Query: 307 A--LENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAV 364
A L+ + +E +E + + + +D +Q EE RK ++ L
Sbjct: 846 AQQLQEEEDGLQEDQERRRS---QEQRRDQKWRWQLEEE-----------RKRRRHTLYA 891
Query: 365 K--LRNRPSKQEL---EDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNIL 419
K L+ + K++ E+ R E+R+ Q+ + + ++L Q E+L R
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE--EQLLREERE 949
Query: 420 KQRNDQTEQEERRE--IKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQ----DYD 473
K+R + E++ R++ ++Q+ + L + P ++R+ R + ++ + Q + +
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 474 RRADKPWTR-------LSAADKAAIRKELNEYKSNEME 504
+R + W R L ++ +R+E + + E E
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047
Score = 34.3 bits (77), Expect = 0.28
Identities = 44/204 (21%), Positives = 84/204 (41%), Gaps = 41/204 (20%)
Query: 251 RVIEELHRALATKHRQDSFQGRESKGSPKKRL--DVRLSRTSSVERGKEREEAWSFDGAL 308
R ++E L RQ+ + R+ + ++RL + +L R ER +++EE
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER------- 321
Query: 309 ENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRN 368
+E +E +E Q EE + R+ ++E +LR
Sbjct: 322 -------REQQERRE---------------QQEERREQQL------RREQEERREQQLR- 352
Query: 369 RPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQ 428
+++ E+R R ++E + QQ+ + R Q+ E+ RR +R Q +
Sbjct: 353 ---REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 409
Query: 429 EERREIKQRLTRKLNQRPTVDELR 452
E++ +Q+L R+ R +E R
Sbjct: 410 EQQLRREQQLRREQQLRREQEEER 433
Score = 34.3 bits (77), Expect = 0.28
Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 6/95 (6%)
Query: 369 RPSKQELEDRNIFPRRTDEERQEIRQQIEMKL--SKRLSQRPAVEELER----RNILKQR 422
R +Q+L + + EE+Q RQ++E K ++L Q E+L R R IL++
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753
Query: 423 NDQTEQEERREIKQRLTRKLNQRPTVDELRDRKIL 457
+ E+EE++ +Q RK + + + R+ + L
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL 1788
Score = 33.5 bits (75), Expect = 0.48
Identities = 49/272 (18%), Positives = 114/272 (41%), Gaps = 12/272 (4%)
Query: 243 VHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAW 302
+HR + ++E + + Q Q R+ K +++L R R +ER+ +
Sbjct: 1524 LHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQL--RQEREEQQLSRQERDRKF 1581
Query: 303 SFDGALENKRTAAKESEENKENLIINSELKD-----DLLLYQDEEALNDSIISGTLPRKC 357
+ ++ ++ E+++ L + D +DE+ L + ++
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
Query: 358 KKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELE--R 415
++ L + + R ++E + R+ R+ EE Q +++ E +L ++ R EE + R
Sbjct: 1642 DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR 1701
Query: 416 RNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRR 475
R +++ Q EQ+ RR Q L RK + + + +++ L R Y ++ + +
Sbjct: 1702 RQERERKFLQEEQQLRR---QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758
Query: 476 ADKPWTRLSAADKAAIRKELNEYKSNEMEVHA 507
++ R D+ +E + E ++ +
Sbjct: 1759 REEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
Score = 32.0 bits (71), Expect = 1.4
Identities = 45/265 (16%), Positives = 108/265 (40%), Gaps = 32/265 (12%)
Query: 254 EELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRT 313
++L L + +D RE + ++ D +ER +++E + E K+
Sbjct: 1265 QDLQHLLGEQQERD----REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320
Query: 314 AAKESEENKENLIINSELKDDLLLYQDEEAL------------NDSIISGTLPRKCKKEL 361
+E EE + + + +++ L Q+ E + + RK +E
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 362 LAVKLRNRPSK------------QELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPA 409
++ + R K +E + R R+ EE Q++ +Q + + Q+
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
Query: 410 VEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKA 469
+E ER+ + +++ + E+ + +++L ++ ++ + RDRK F + + +
Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK----FLEEEQQLRR 1496
Query: 470 QDYDRRADKPWTRLSAADKAAIRKE 494
Q+ DR+ + R ++ + +E
Sbjct: 1497 QERDRKFREQELRSQEPERKFLEEE 1521
Score = 31.6 bits (70), Expect = 1.8
Identities = 49/224 (21%), Positives = 92/224 (41%), Gaps = 16/224 (7%)
Query: 263 KHRQDS-FQGRESKGSPKKRLDVRLSRTSSVE----RGKEREEAWSFDGALENKRTAAKE 317
+ RQD FQ E K K+ +R E R +E +E LE + +
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 318 SEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELED 377
EE ++ + E L Q+EE + +++ + R + ++E E+
Sbjct: 291 QEEEQQQQRLRRE--QQLRRKQEEERREQQEERREQQERREQQ---EERREQQLRREQEE 345
Query: 378 RNIFPRRTDEERQEIRQQI--EMKLSKRLSQRPAVEELERRNILKQRND-QTEQEERREI 434
R R ++E + QQ+ E + +R Q ++L R L++ + EQ+ RRE
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 435 KQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADK 478
+ R ++L + +LR + L R + + + +RR +
Sbjct: 406 QLRREQQLRRE---QQLRREQQLRREQEEERHEQKHEQERREQR 446
Score = 31.6 bits (70), Expect = 1.8
Identities = 50/251 (19%), Positives = 106/251 (42%), Gaps = 22/251 (8%)
Query: 270 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINS 329
Q R+ + + + +LSR + +E E+ E +R +E ++ ++
Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ---ERERKFLEEEQQLRQERHRKF 1463
Query: 330 ELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSK---QELEDRNIFPRRTD 386
++ LL ++E+ L+ RK +E ++ + R K QEL + + +
Sbjct: 1464 REEEQLLQEREEQQLHRQ----ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 387 EERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRP 446
EE+Q RQQ + K L + + ER +Q D+ +EE + ++R ++L+++
Sbjct: 1520 EEQQLHRQQRQRKF---LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Query: 447 TVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVH 506
RDRK + + + Q+ +R+ + +L + ++ + K E E
Sbjct: 1577 -----RDRKFRLE----EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
Query: 507 ASSKHLTRFHR 517
+ + HR
Sbjct: 1628 LQEREEQQLHR 1638
Score = 29.6 bits (65), Expect = 6.9
Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 13/106 (12%)
Query: 383 RRTDEERQEIRQQIEMKLSKRLSQRPAVEELERR-NILKQRNDQTEQEE--RREIKQRLT 439
R+ EE Q++R+Q + + Q+ +ELER+ +Q +TEQE+ R+E +++
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750
Query: 440 RKLNQRPTVDEL------RDRKI----LIRFSDYVEVAKAQDYDRR 475
+ RP +E RDRK +R + ++Q+ DR+
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 45.1 bits (105), Expect = 2e-04
Identities = 67/389 (17%), Positives = 141/389 (36%), Gaps = 36/389 (9%)
Query: 79 DAESKTCNPDGGPRSVQSE--PPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHL 136
D++S + + D P++ + + P T K++T +P S SS++
Sbjct: 168 DSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSS 227
Query: 137 DDAAKMPSASSGEEADA-----------GSLLPTTNELSQALAGADSLDSPPRPLERSVG 185
DD+ + +A++ ++ + PT S + +D + +P++ G
Sbjct: 228 DDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPG 287
Query: 186 QLPSPPLLPTPPPKASSKT---TKNVTGQATLFQA-SSMKSADPSLRGQLSTPTGSPHLT 241
S P PPPK S T K V Q + + S +D S + PT +
Sbjct: 288 PYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSK 347
Query: 242 TVHRPLPPSRVIEELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSS--VERGKERE 299
+P P + E + + +D + G+ K + T S V+ +
Sbjct: 348 ATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPK 407
Query: 300 EAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKK 359
+ L ++ + SEE + EE +++ T P+ K
Sbjct: 408 QPVGGGQKLLTRKADSSSSEEESSS---------------SEEEKTKKMVATTKPKATAK 452
Query: 360 ELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLS--QRPAVEELERRN 417
L++ + P + ++EE ++ + K ++++ P+ ++
Sbjct: 453 AALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKG 512
Query: 418 ILKQRNDQTEQEERREIKQRLTRKLNQRP 446
+ N + + E +++L K + RP
Sbjct: 513 KAESSNSSSSDDSSEEEEEKLKGKGSPRP 541
Score = 36.6 bits (83), Expect = 0.057
Identities = 74/369 (20%), Positives = 133/369 (36%), Gaps = 41/369 (11%)
Query: 35 KPWKWRKKKNEKLKQTTSALEKKMAGRQGREELIKKGLLEMMEQDAESKTCNPDGGPRSV 94
KP K + + ++ KK G Q ++ ++K +Q ES + D S
Sbjct: 280 KPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEK------QQPVESSEDSSDESDSSS 333
Query: 95 QSEPPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAG 154
+ E P ++ +P P A + S D S ++ D+A P+ ++ ++
Sbjct: 334 EEEKKPPTKAVVSKATTKP--PPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKP 391
Query: 155 SLLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQATL 214
++ + + A A + + L R S + + + K +AT
Sbjct: 392 AVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATA 451
Query: 215 FQASSM--KSADPSLRGQLSTPTGSPHLTTVHRPLPPSRVIEELHRALATKHRQDSFQGR 272
A S+ K A R S S S EE A K + G
Sbjct: 452 KAALSLPAKQAPQGSRDSSSDSDSSS-----------SEEEEEKTSKSAVKKKPQKVAGG 500
Query: 273 ESKGSP---KKRLDVRLSRTSSVERGKEREEAWSFDG-----ALENKRTAAKESEENKEN 324
+ P KK + +SS + +E EE G A + T+A ++ K
Sbjct: 501 AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAA 560
Query: 325 LIINSELKDDLLLYQDEEALNDSII---SGTLPRKCKKELLAVKLRNRPSKQELEDRNIF 381
NSE ++EE +++ SG+L ++ + E + K +L+ N F
Sbjct: 561 K--NSE-------EEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTF 611
Query: 382 PRRTDEERQ 390
P+R E++
Sbjct: 612 PKRKKGEKR 620
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/187 (20%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 293 ERGKEREEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGT 352
++ ER+ ++ R E +E + + E ++++ ++E SI++
Sbjct: 291 DQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEV---PEQEGEPSSIVNVP 347
Query: 353 LPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQ----RP 408
+++ L ++ N+ + L + + + E++E ++Q+ + KR+ Q R
Sbjct: 348 GESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRR 407
Query: 409 AVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAK 468
+EE +RR +R + EQ R + ++R +L +R +E R R + V +
Sbjct: 408 RLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR----AEEEKRRVER 463
Query: 469 AQDYDRR 475
Q+Y RR
Sbjct: 464 EQEYIRR 470
Score = 37.7 bits (86), Expect = 0.025
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 23/165 (13%)
Query: 293 ERGKEREEAWSFDGALENKRTAAKESEENKENLIIN----SELKDDLLLYQDE-----EA 343
+RG++ E + + G+ E + ++ E + + I+N S L+ D L Q E EA
Sbjct: 312 KRGEKDETEYEYSGSEEEEEEVPEQ--EGEPSSIVNVPGESTLRRDFLRLQQENKERSEA 369
Query: 344 LN-DSIISGTLPRK---CKKELLAVKLRN-------RPSKQELEDRNIFPRRTDEERQEI 392
L ++ R+ K++LLA + + R +E + R RR E Q
Sbjct: 370 LRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRR 429
Query: 393 RQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEE-RREIKQ 436
R+Q E + + L +R EE RR ++R + EQE RR++++
Sbjct: 430 REQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEE 474
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/187 (20%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 293 ERGKEREEAWSFDGALENKRTAAKESEENKENLIINSELKDDLLLYQDEEALNDSIISGT 352
++ ER+ ++ R E +E + + E ++++ ++E SI++
Sbjct: 291 DQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEV---PEQEGEPSSIVNVP 347
Query: 353 LPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQ----RP 408
+++ L ++ N+ + L + + + E++E ++Q+ + KR+ Q R
Sbjct: 348 GESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRR 407
Query: 409 AVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAK 468
+EE +RR +R + EQ R + ++R +L +R +E R R + V +
Sbjct: 408 RLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR----AEEEKRRVER 463
Query: 469 AQDYDRR 475
Q+Y RR
Sbjct: 464 EQEYIRR 470
Score = 37.7 bits (86), Expect = 0.025
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 23/165 (13%)
Query: 293 ERGKEREEAWSFDGALENKRTAAKESEENKENLIIN----SELKDDLLLYQDE-----EA 343
+RG++ E + + G+ E + ++ E + + I+N S L+ D L Q E EA
Sbjct: 312 KRGEKDETEYEYSGSEEEEEEVPEQ--EGEPSSIVNVPGESTLRRDFLRLQQENKERSEA 369
Query: 344 LN-DSIISGTLPRK---CKKELLAVKLRN-------RPSKQELEDRNIFPRRTDEERQEI 392
L ++ R+ K++LLA + + R +E + R RR E Q
Sbjct: 370 LRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRR 429
Query: 393 RQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEE-RREIKQ 436
R+Q E + + L +R EE RR ++R + EQE RR++++
Sbjct: 430 REQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEE 474
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 45.1 bits (105), Expect = 2e-04
Identities = 80/383 (20%), Positives = 148/383 (38%), Gaps = 57/383 (14%)
Query: 148 GEEADAGSLLPTTNELSQALAGADSLD-----SPPRPLERSVG--QLPSPPLLPTPPPKA 200
G+EA +G ++ + A SL SP R E S G + PS P++ KA
Sbjct: 241 GKEALSGGEASLVEKVKRGQRTATSLPVVNFGSPLRRCEFSGGIPKRPSSPVISKTATKA 300
Query: 201 ---SSKTTKN-VTGQATLFQASSMKSADPSLRGQLSTPTGSPHLTTVHRPLPPSRVIEEL 256
S KTTK G ++ ++ D R + T+ + + E L
Sbjct: 301 YPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEAL 360
Query: 257 HRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAK 316
+ + KH + + G + + + + G+ + L KR A+
Sbjct: 361 EKHVVDKHASEK-HAAAAGGKAENSAALGKPTAGTTDAGEAAK-------ILAEKRRQAR 412
Query: 317 ESEENKENLIINSELKDDLLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELE 376
+E +E + E +D L + EE L RK ++E L +L KQE E
Sbjct: 413 LQKEQEEQERVEKEEQDRL---EREE----------LKRKAEEERL--RLEEEARKQEEE 457
Query: 377 DRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQ 436
R+ EE ++ ++ E + + ++R A EEL +LK++ +Q +QE+ KQ
Sbjct: 458 ------RKRQEEEKKKQEGEEKRKAGEEAKRKAEEEL----LLKEKQEQEKQEKAMIEKQ 507
Query: 437 RLTRKLNQRPTVDELRDRKILI-------------RFSDYVEVAKAQDYDRRADKPWTRL 483
+ + R +++R + I R + ++ + D + K ++
Sbjct: 508 KEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVPPQVKKEDPKV 567
Query: 484 SAADKAAIRKELNEYKSNEMEVH 506
+ K+ N+ME++
Sbjct: 568 GVQPAVCVEKKTKLVVPNKMEIN 590
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 44.7 bits (104), Expect = 2e-04
Identities = 57/240 (23%), Positives = 87/240 (36%), Gaps = 36/240 (15%)
Query: 40 RKKKNEKLKQTTSALEKKMAGRQGREELIKKGLLEMMEQDAESKTCNPDGGPRSVQSEPP 99
RKKK ++ +A KM G++ + + E +A+ PRSV+ E
Sbjct: 401 RKKK----ERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKS 456
Query: 100 TPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPT 159
P +E + ++ T +V LD+ +S HL K + + T
Sbjct: 457 APDTELVNVTHLNTEVKNSSDTGKVKLDE--NSEKHLVKDLKAQGTRDSKPIALKEEIVT 514
Query: 160 TNELS----QALAGADSLDSPPRPLERSVGQLPSPPLLPTPP------------------ 197
E + ++ SPP PL + +PPL P PP
Sbjct: 515 PKETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFS 574
Query: 198 --PKASSKTTKNVTGQATLFQASSMKSADP---SLRGQLSTPTGSPHL---TTVHRPLPP 249
P +S+ T T T +S S P S++ Q+S PHL T PLPP
Sbjct: 575 QVPASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPP 634
Score = 32.3 bits (72), Expect = 1.1
Identities = 50/198 (25%), Positives = 70/198 (35%), Gaps = 38/198 (19%)
Query: 88 DGGPRSVQSEPPTPKSETLTSED---------AQPGSPLATGTD--QVSLDKPLSSAAHL 136
D P +++ E TPK ET TSE A P PL T T Q PL L
Sbjct: 502 DSKPIALKEEIVTPK-ETETSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPAL 560
Query: 137 DDAAKMPSA----SSGEEADAGSLLPTTNELSQALAGADSLDSP---------------P 177
+P + S + +L P+T+ + A++ + P P
Sbjct: 561 PQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVKTQVSVTAAIP 620
Query: 178 RPLERSVGQLPSPPLLP------TPPPKASSKTTKNVTGQATLFQASSMKSADPSLRGQL 231
++ LP PPLLP +P SK K Q T + + P L G
Sbjct: 621 HLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLTDL-PLPPELPGGD 679
Query: 232 STPTGSPHLTTVHRPLPP 249
+P SP + P P
Sbjct: 680 LSPPDSPEPKAITPPQQP 697
Score = 31.6 bits (70), Expect = 1.8
Identities = 38/158 (24%), Positives = 59/158 (37%), Gaps = 23/158 (14%)
Query: 103 SETLTSEDAQPGSPLAT----GTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLP 158
SET+ E++ +P A +Q +L+ + A + A + S + AGSL
Sbjct: 1170 SETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEE 1229
Query: 159 TTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPK---------ASSKTTKNVT 209
++ + G +P P E + + P P P PPP +S+ N
Sbjct: 1230 NNSDKNSGPQGPRR--TPTMPQEEAAEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPA 1287
Query: 210 GQATLFQASSMKSADPSLRGQLSTPTGSPHLTTVHRPL 247
A L Q S A+P P PH RP+
Sbjct: 1288 VTAALLQLLSQPEAEP--------PGHLPHEHQALRPM 1317
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,372,876
Number of Sequences: 37866
Number of extensions: 1092945
Number of successful extensions: 10153
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 924
Number of HSP's that attempted gapping in prelim test: 7412
Number of HSP's gapped (non-prelim): 2780
length of query: 518
length of database: 18,247,518
effective HSP length: 107
effective length of query: 411
effective length of database: 14,195,856
effective search space: 5834496816
effective search space used: 5834496816
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.