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Search of human proteins with 33636719
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33636719 translocase of inner mitochondrial membrane 44
[Homo sapiens]
(452 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33636719 translocase of inner mitochondrial membrane 44 [Homo... 895 0.0
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 47 5e-05
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 44 3e-04
gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sap... 42 0.001
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap... 42 0.001
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap... 42 0.001
gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sap... 42 0.001
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 40 0.003
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 40 0.003
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 40 0.003
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 40 0.003
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 40 0.003
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 40 0.003
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 40 0.003
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 40 0.003
gi|71061468 centromere protein E [Homo sapiens] 40 0.006
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 39 0.007
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 39 0.007
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 39 0.010
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 38 0.016
gi|31982906 cingulin-like 1 [Homo sapiens] 38 0.016
gi|120587019 zinc finger protein 318 [Homo sapiens] 38 0.016
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 37 0.028
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 37 0.028
gi|118498356 kinectin 1 isoform a [Homo sapiens] 37 0.037
gi|33620775 kinectin 1 isoform a [Homo sapiens] 37 0.037
gi|16262452 cingulin [Homo sapiens] 37 0.037
gi|40805862 tumor protein D52-like 2 isoform f [Homo sapiens] 37 0.048
gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens] 36 0.063
gi|222537714 taxilin beta [Homo sapiens] 35 0.11
>gi|33636719 translocase of inner mitochondrial membrane 44 [Homo
sapiens]
Length = 452
Score = 895 bits (2314), Expect = 0.0
Identities = 452/452 (100%), Positives = 452/452 (100%)
Query: 1 MAAAALRSGWCRCPRRCLGSGIQFLSSHNLPHGSTYQMRRPGGELPLSKSYSSGNRKGFL 60
MAAAALRSGWCRCPRRCLGSGIQFLSSHNLPHGSTYQMRRPGGELPLSKSYSSGNRKGFL
Sbjct: 1 MAAAALRSGWCRCPRRCLGSGIQFLSSHNLPHGSTYQMRRPGGELPLSKSYSSGNRKGFL 60
Query: 61 SGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRK 120
SGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRK
Sbjct: 61 SGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRK 120
Query: 121 KLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALS 180
KLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALS
Sbjct: 121 KLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALS 180
Query: 181 QGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEALGVVLHKDSK 240
QGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEALGVVLHKDSK
Sbjct: 181 QGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEALGVVLHKDSK 240
Query: 241 WYQQWKDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKVTDLLGGLFSKTEMSEVL 300
WYQQWKDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKVTDLLGGLFSKTEMSEVL
Sbjct: 241 WYQQWKDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKVTDLLGGLFSKTEMSEVL 300
Query: 301 TEILRVDPAFDKDRFLKQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKA 360
TEILRVDPAFDKDRFLKQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKA
Sbjct: 301 TEILRVDPAFDKDRFLKQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKA 360
Query: 361 LGLQFHSRILDIDNVDLAMGKMMEQGPVLIITFQAQLVMVVRNPKGEVVEGDPDKVLRML 420
LGLQFHSRILDIDNVDLAMGKMMEQGPVLIITFQAQLVMVVRNPKGEVVEGDPDKVLRML
Sbjct: 361 LGLQFHSRILDIDNVDLAMGKMMEQGPVLIITFQAQLVMVVRNPKGEVVEGDPDKVLRML 420
Query: 421 YVWALCRDQDELNPYAAWRLLDISASSTEQIL 452
YVWALCRDQDELNPYAAWRLLDISASSTEQIL
Sbjct: 421 YVWALCRDQDELNPYAAWRLLDISASSTEQIL 452
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 46.6 bits (109), Expect = 5e-05
Identities = 43/183 (23%), Positives = 79/183 (43%), Gaps = 11/183 (6%)
Query: 60 LSGLLDNVKQELAKNKEMKESIKKFRDEARRLEES-DVLQEARRKYKTIESETVRTSEVL 118
+SGL ++ E A ++++ IK+ + LEE + + +R K + S+ R E +
Sbjct: 1091 MSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI 1150
Query: 119 RKKLGELTGTVKESLHEVSKSDLG-RKIKEGVEE--------AAKTAKQSAESVSKGGEK 169
++L E G + K + +K++ +EE AA K+ A+SV++ GE+
Sbjct: 1151 SERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQ 1210
Query: 170 LGRTAAFR-ALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNE 228
+ + L + +K EIDD + L K D+ E K E +
Sbjct: 1211 IDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQ 1270
Query: 229 EAL 231
+ L
Sbjct: 1271 QRL 1273
Score = 32.7 bits (73), Expect = 0.69
Identities = 67/327 (20%), Positives = 124/327 (37%), Gaps = 53/327 (16%)
Query: 46 PLSKSYSSGNRKGFLSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYK 105
PL KS + + + K+ELAK + ++ +++ + E++D+ + + +
Sbjct: 842 PLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEE-KMVTLMQEKNDLQLQVQAEAD 900
Query: 106 TIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK 165
++ R ++++ K+ L KIKE E A + +AE
Sbjct: 901 SLADAEERCDQLIKTKI-----------------QLEAKIKEVTERAEDEEEINAE---- 939
Query: 166 GGEKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFE 225
TA R L +KK+IDD L + ++ + T E KV
Sbjct: 940 ------LTAKKRKLEDECSELKKDIDDLEL----TLAKVEKEKHAT--------ENKVKN 981
Query: 226 PNEEALGVVLHKDSKWYQQWKDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKVTD 285
EE G+ D + K+ K + + ++ N +A L +V D
Sbjct: 982 LTEEMAGL----DETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1037
Query: 286 LLGGLFSKTEMSEVLTEILRVDPAFDKDRFLKQCENDIIPNVLEAMISGELDILKDWCYE 345
L G L + ++ ++ R + D L Q I N + + + LK +E
Sbjct: 1038 LEGSL---EQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLD----EKLKKKEFE 1090
Query: 346 ATYSQLAHPIQQAKALGLQFHSRILDI 372
S L I+ +ALG+Q +I ++
Sbjct: 1091 --MSGLQSKIEDEQALGMQLQKKIKEL 1115
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 43.9 bits (102), Expect = 3e-04
Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 7/160 (4%)
Query: 64 LDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLG 123
L+ K+EL KN ++ +++ K + E L V E R +++ES + +T + L +LG
Sbjct: 733 LEREKEELRKNVDLLKALGK-KSERLELSYQSVSAENLRLQQSLESSSHKT-QTLESELG 790
Query: 124 ELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALSQGV 183
EL + ++ L EG E+ K +Q + K + L + A + L Q V
Sbjct: 791 ELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEA--KRLWQQV 848
Query: 184 ESVKKEIDDSVLGQTGPYRRPQRLRK---RTEFAGDKFKE 220
E +DDS + + + L K R A K KE
Sbjct: 849 ELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKE 888
>gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo
sapiens]
Length = 436
Score = 42.0 bits (97), Expect = 0.001
Identities = 59/240 (24%), Positives = 103/240 (42%), Gaps = 30/240 (12%)
Query: 60 LSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEAR--------------RKYK 105
LS L N++ EL E ++K R+E + + E+ V Q R+Y+
Sbjct: 123 LSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYE 182
Query: 106 TIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK 165
+ + +E + +L E + + HE SK ++ E +E K + S + K
Sbjct: 183 KLRDTYIEEAEKYKMQLQEQFDNLNAA-HETSKLEIEASHSEKLELLKKAYEASLSEIKK 241
Query: 166 GGEKLGRTAAFRALSQGVESVKKEIDD-----SVLGQTGPYRRPQRLRKRTEFAGDKFKE 220
G E + + + LS+ ES++K+I+D L + + ++ R+ E A K +
Sbjct: 242 GHE-IEKKSLEDLLSEKQESLEKQINDLKSENDALNE--KLKSEEQKRRAREKANLKNPQ 298
Query: 221 EKVFEPNEEALGVVLH-KDSKWYQQWKDFK----ENNVVFNRFFEMKMKYDESDNAFIRA 275
E E+L VL K+ K +QQ D K E V N K+K + +N ++A
Sbjct: 299 IMYLEQELESLKAVLEIKNEKLHQQ--DIKLMKMEKLVDNNTALVDKLKRFQQENEELKA 356
>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
Length = 1270
Score = 42.0 bits (97), Expect = 0.001
Identities = 59/240 (24%), Positives = 103/240 (42%), Gaps = 30/240 (12%)
Query: 60 LSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEAR--------------RKYK 105
LS L N++ EL E ++K R+E + + E+ V Q R+Y+
Sbjct: 957 LSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYE 1016
Query: 106 TIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK 165
+ + +E + +L E + + HE SK ++ E +E K + S + K
Sbjct: 1017 KLRDTYIEEAEKYKMQLQEQFDNLNAA-HETSKLEIEASHSEKLELLKKAYEASLSEIKK 1075
Query: 166 GGEKLGRTAAFRALSQGVESVKKEIDD-----SVLGQTGPYRRPQRLRKRTEFAGDKFKE 220
G E + + + LS+ ES++K+I+D L + + ++ R+ E A K +
Sbjct: 1076 GHE-IEKKSLEDLLSEKQESLEKQINDLKSENDALNE--KLKSEEQKRRAREKANLKNPQ 1132
Query: 221 EKVFEPNEEALGVVLH-KDSKWYQQWKDFK----ENNVVFNRFFEMKMKYDESDNAFIRA 275
E E+L VL K+ K +QQ D K E V N K+K + +N ++A
Sbjct: 1133 IMYLEQELESLKAVLEIKNEKLHQQ--DIKLMKMEKLVDNNTALVDKLKRFQQENEELKA 1190
>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sapiens]
Length = 1216
Score = 42.0 bits (97), Expect = 0.001
Identities = 59/240 (24%), Positives = 103/240 (42%), Gaps = 30/240 (12%)
Query: 60 LSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEAR--------------RKYK 105
LS L N++ EL E ++K R+E + + E+ V Q R+Y+
Sbjct: 903 LSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYE 962
Query: 106 TIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK 165
+ + +E + +L E + + HE SK ++ E +E K + S + K
Sbjct: 963 KLRDTYIEEAEKYKMQLQEQFDNLNAA-HETSKLEIEASHSEKLELLKKAYEASLSEIKK 1021
Query: 166 GGEKLGRTAAFRALSQGVESVKKEIDD-----SVLGQTGPYRRPQRLRKRTEFAGDKFKE 220
G E + + + LS+ ES++K+I+D L + + ++ R+ E A K +
Sbjct: 1022 GHE-IEKKSLEDLLSEKQESLEKQINDLKSENDALNE--KLKSEEQKRRAREKANLKNPQ 1078
Query: 221 EKVFEPNEEALGVVLH-KDSKWYQQWKDFK----ENNVVFNRFFEMKMKYDESDNAFIRA 275
E E+L VL K+ K +QQ D K E V N K+K + +N ++A
Sbjct: 1079 IMYLEQELESLKAVLEIKNEKLHQQ--DIKLMKMEKLVDNNTALVDKLKRFQQENEELKA 1136
>gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo
sapiens]
Length = 517
Score = 42.0 bits (97), Expect = 0.001
Identities = 59/240 (24%), Positives = 103/240 (42%), Gaps = 30/240 (12%)
Query: 60 LSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEAR--------------RKYK 105
LS L N++ EL E ++K R+E + + E+ V Q R+Y+
Sbjct: 204 LSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYE 263
Query: 106 TIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK 165
+ + +E + +L E + + HE SK ++ E +E K + S + K
Sbjct: 264 KLRDTYIEEAEKYKMQLQEQFDNLNAA-HETSKLEIEASHSEKLELLKKAYEASLSEIKK 322
Query: 166 GGEKLGRTAAFRALSQGVESVKKEIDD-----SVLGQTGPYRRPQRLRKRTEFAGDKFKE 220
G E + + + LS+ ES++K+I+D L + + ++ R+ E A K +
Sbjct: 323 GHE-IEKKSLEDLLSEKQESLEKQINDLKSENDALNE--KLKSEEQKRRAREKANLKNPQ 379
Query: 221 EKVFEPNEEALGVVLH-KDSKWYQQWKDFK----ENNVVFNRFFEMKMKYDESDNAFIRA 275
E E+L VL K+ K +QQ D K E V N K+K + +N ++A
Sbjct: 380 IMYLEQELESLKAVLEIKNEKLHQQ--DIKLMKMEKLVDNNTALVDKLKRFQQENEELKA 437
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 65 DNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGE 124
DN ++ L +E E +K+ +EA RL S QEA R + E + + + K L E
Sbjct: 2260 DNTQRFL---QEEAEKMKQVAEEAARL--SVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2314
Query: 125 LTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK--GGEKLGRTAAFRA---- 178
V+E+ ++++L ++ KE +E A+ ++ E +++ E G A
Sbjct: 2315 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2374
Query: 179 ---LSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDK 217
+S E +K + + Q QR RK+ E G+K
Sbjct: 2375 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 65 DNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGE 124
DN ++ L +E E +K+ +EA RL S QEA R + E + + + K L E
Sbjct: 2264 DNTQRFL---QEEAEKMKQVAEEAARL--SVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2318
Query: 125 LTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK--GGEKLGRTAAFRA---- 178
V+E+ ++++L ++ KE +E A+ ++ E +++ E G A
Sbjct: 2319 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2378
Query: 179 ---LSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDK 217
+S E +K + + Q QR RK+ E G+K
Sbjct: 2379 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2420
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 65 DNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGE 124
DN ++ L +E E +K+ +EA RL S QEA R + E + + + K L E
Sbjct: 2260 DNTQRFL---QEEAEKMKQVAEEAARL--SVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2314
Query: 125 LTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK--GGEKLGRTAAFRA---- 178
V+E+ ++++L ++ KE +E A+ ++ E +++ E G A
Sbjct: 2315 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2374
Query: 179 ---LSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDK 217
+S E +K + + Q QR RK+ E G+K
Sbjct: 2375 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 65 DNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGE 124
DN ++ L +E E +K+ +EA RL S QEA R + E + + + K L E
Sbjct: 2228 DNTQRFL---QEEAEKMKQVAEEAARL--SVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2282
Query: 125 LTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK--GGEKLGRTAAFRA---- 178
V+E+ ++++L ++ KE +E A+ ++ E +++ E G A
Sbjct: 2283 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2342
Query: 179 ---LSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDK 217
+S E +K + + Q QR RK+ E G+K
Sbjct: 2343 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2384
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 65 DNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGE 124
DN ++ L +E E +K+ +EA RL S QEA R + E + + + K L E
Sbjct: 2397 DNTQRFL---QEEAEKMKQVAEEAARL--SVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2451
Query: 125 LTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK--GGEKLGRTAAFRA---- 178
V+E+ ++++L ++ KE +E A+ ++ E +++ E G A
Sbjct: 2452 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2511
Query: 179 ---LSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDK 217
+S E +K + + Q QR RK+ E G+K
Sbjct: 2512 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2553
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 65 DNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGE 124
DN ++ L +E E +K+ +EA RL S QEA R + E + + + K L E
Sbjct: 2238 DNTQRFL---QEEAEKMKQVAEEAARL--SVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2292
Query: 125 LTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK--GGEKLGRTAAFRA---- 178
V+E+ ++++L ++ KE +E A+ ++ E +++ E G A
Sbjct: 2293 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2352
Query: 179 ---LSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDK 217
+S E +K + + Q QR RK+ E G+K
Sbjct: 2353 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2394
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 65 DNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGE 124
DN ++ L +E E +K+ +EA RL S QEA R + E + + + K L E
Sbjct: 2246 DNTQRFL---QEEAEKMKQVAEEAARL--SVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2300
Query: 125 LTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK--GGEKLGRTAAFRA---- 178
V+E+ ++++L ++ KE +E A+ ++ E +++ E G A
Sbjct: 2301 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2360
Query: 179 ---LSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDK 217
+S E +K + + Q QR RK+ E G+K
Sbjct: 2361 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2402
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 65 DNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGE 124
DN ++ L +E E +K+ +EA RL S QEA R + E + + + K L E
Sbjct: 2287 DNTQRFL---QEEAEKMKQVAEEAARL--SVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2341
Query: 125 LTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSK--GGEKLGRTAAFRA---- 178
V+E+ ++++L ++ KE +E A+ ++ E +++ E G A
Sbjct: 2342 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2401
Query: 179 ---LSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDK 217
+S E +K + + Q QR RK+ E G+K
Sbjct: 2402 QLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2443
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 39.7 bits (91), Expect = 0.006
Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 12/104 (11%)
Query: 66 NVKQELAKNKEMKESIKKFRDEARRLEES---------DVLQEARRKYKTIESETVRTSE 116
N+ Q+L +N E +S+ K RD RR+EE+ + LQE + + I+ E ++T+
Sbjct: 1872 NLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQE-LKTAR 1930
Query: 117 VLRKKLGELTGTVKESLHE--VSKSDLGRKIKEGVEEAAKTAKQ 158
+L K+ E ++E + E + SD+ + + + +E K ++
Sbjct: 1931 MLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQE 1974
Score = 37.7 bits (86), Expect = 0.022
Identities = 53/251 (21%), Positives = 101/251 (40%), Gaps = 36/251 (14%)
Query: 66 NVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTI--ESETVRT-SEVLRKKL 122
N + L + K+S R E RL ++ QE++ + K++ E + ++T E L K
Sbjct: 1306 NELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKH 1365
Query: 123 GELTGTVKESLHEV----SKSDLGRKIKEGVEEAAKTAKQSAESVSKGG-------EKLG 171
+L ++E+L ++ SK + +KE E K + + K E LG
Sbjct: 1366 DQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLG 1425
Query: 172 RTAAFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEAL 231
+ + ++SV KE DD QRL++ + D+ KE +E +
Sbjct: 1426 LSKRLQESHDEMKSVAKEKDDL-----------QRLQEVLQSESDQLKEN-----IKEIV 1469
Query: 232 GVVLHKDSKWYQQWKDFKENNVVFNRFFEMKMKYDESD---NAFIRASRALTDKVTDLLG 288
L + + KE N E+++ E + + + A+ DK+ + +
Sbjct: 1470 AKHLETEEELKVAHCCLKEQEETIN---ELRVNLSEKETEISTIQKQLEAINDKLQNKIQ 1526
Query: 289 GLFSKTEMSEV 299
++ K E +
Sbjct: 1527 EIYEKEEQFNI 1537
Score = 30.8 bits (68), Expect = 2.6
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 24/121 (19%)
Query: 69 QELAKNKEMKESIKKFRDEARRLEES-----DVLQEARRKYKTIESETVRTSEVLRKKLG 123
Q L +N E S+ K RD+ R +EE+ D L+E R+ T + E +++ L
Sbjct: 1672 QILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLK 1731
Query: 124 E-------LTGTVKESLHEVS--KSDLGR----------KIKEGVEEAAKTAKQSAESVS 164
E L G V E +E+S + DL KI+E + A K+ E++
Sbjct: 1732 EHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETID 1791
Query: 165 K 165
K
Sbjct: 1792 K 1792
Score = 30.4 bits (67), Expect = 3.4
Identities = 38/176 (21%), Positives = 77/176 (43%), Gaps = 28/176 (15%)
Query: 63 LLDNVKQELAKNKEMKESIKK----FRDEARRLEESDV-LQEARRKYKTIESETVRTSEV 117
L +N+K+ +AK+ E +E +K +++ + E V L E + TI+ + ++
Sbjct: 1461 LKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDK 1520
Query: 118 LRKKLGEL-----------TGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKG 166
L+ K+ E+ V+E ++E+ + RK K+ +A QS ES
Sbjct: 1521 LQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKD-------SALQSIES---- 1569
Query: 167 GEKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEK 222
+ L T + + ++ + KE ++ Q +L++ T+ K KE +
Sbjct: 1570 -KMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQ 1624
Score = 28.9 bits (63), Expect = 10.0
Identities = 55/279 (19%), Positives = 103/279 (36%), Gaps = 45/279 (16%)
Query: 46 PLSKSYSSGNRKGFLSGL---LDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARR 102
P +K + N + L+ L DN+ + + + KE ++ E L+E + L+ +
Sbjct: 486 PATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTK 545
Query: 103 KYKTIESETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAES 162
K + ++ L ++ L VK + EV DL ++ VE ++ +
Sbjct: 546 KDQEMQ---------LIHEISNLKNLVKHA--EVYNQDLENELSSKVE----LLREKEDQ 590
Query: 163 VSKGGEKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEK 222
+ K E + SQ +E++K ++ S+ P + Q L A D +E
Sbjct: 591 IKKLQEYID--------SQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESA 642
Query: 223 VFEPNEEALGVVLHKDSKWYQQWKDF-------------------KENNVVFNRFFEMKM 263
L + + + Y+Q ++ KE FN ++
Sbjct: 643 FLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTS 702
Query: 264 KYDESDNAFIRASRALTDKVTDLLGGLFSKTEMSEVLTE 302
D + + L K+TDL L + E +E L E
Sbjct: 703 LIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALRE 741
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 39.3 bits (90), Expect = 0.007
Identities = 35/179 (19%), Positives = 80/179 (44%), Gaps = 20/179 (11%)
Query: 68 KQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGELTG 127
++++ + +E ++ +K R++ +R E+ + K + E E +R E + ++ E G
Sbjct: 356 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE-EKIREQEEMMQEQEEKMG 414
Query: 128 TVKESLHEVSKS----------------DLGRKIKEGVEEAAKTAKQSAESVSKGGEKLG 171
+E + E + + +KI+E E+ + + E K GE+ G
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 172 RTAAFRALSQGVESVKKEIDDSVLGQTGPYR-RPQRLRKRTEFAGDKFKEEKVFEPNEE 229
+ A Q E + ++ + Q R + +++R++ E + +EEK++E E+
Sbjct: 475 KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE--QEEKMWEQEEK 531
Score = 30.4 bits (67), Expect = 3.4
Identities = 38/198 (19%), Positives = 82/198 (41%), Gaps = 24/198 (12%)
Query: 65 DNVKQELAKNKEMKESIKKFRDEARRLEE------------SDVLQEARRKYKTIES--- 109
+ +++ K +E +E I++ ++ RR EE +++ E K + +E
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354
Query: 110 --ETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGG 167
E +R E R++ ++ K E KI+E E+ + + E K G
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 168 EKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYR-RPQRLRKRTEFAGDKFKEEKVFEP 226
E+ + Q E + ++ + Q R + +++R++ E + +EEK+ E
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE--QEEKMGEQ 472
Query: 227 NEEALGVVLHKDSKWYQQ 244
G + +++K +Q
Sbjct: 473 E----GKMCEQEAKMQEQ 486
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 39.3 bits (90), Expect = 0.007
Identities = 39/189 (20%), Positives = 87/189 (46%), Gaps = 22/189 (11%)
Query: 52 SSGNRKGFLSGLLDNVKQELAKNKEMKESIKKFRDE-ARRLEESDVLQE--------ARR 102
S K L DN+K E+ + KE SI +DE +R+ E++ + A++
Sbjct: 467 SLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKK 526
Query: 103 KYKTIESE------TVRTSEVLRKKLGELTGTVKE----SLHEVSKSDLGRKIKEGVEEA 152
+ K I+ E + T+++L++K ++ G ++E S ++ S++ +K++ +E
Sbjct: 527 EIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKEN 586
Query: 153 AKTAKQSAESVSKGGEKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTE 212
+ + V + E+L + + G E V+K+ +++ R ++ R +
Sbjct: 587 ENMVAKLNKKVKELEEELQH---LKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQ 643
Query: 213 FAGDKFKEE 221
D+ +E+
Sbjct: 644 VDMDELEEK 652
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 38.9 bits (89), Expect = 0.010
Identities = 50/189 (26%), Positives = 83/189 (43%), Gaps = 18/189 (9%)
Query: 46 PLSKSYSSGNRKGFLSGLLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEA--RRK 103
P+ K+Y KG + K E + + + ++ RDE +R +E + + RRK
Sbjct: 17 PVPKTYVPKLGKGDVKD-----KFEAMQRAREERNQRRSRDEKQRRKEQYIREREWNRRK 71
Query: 104 YKTIE-----SETVRTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQ 158
+ E E +S+V + + +LTGTVK E+ K + K EE + +Q
Sbjct: 72 QEIKEMLASDDEEDVSSKVEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQ 131
Query: 159 SAESVSKGGEKLGRTA--AFRALSQGVESVKKEIDDSVLGQTGP---YRRPQRLRKRTEF 213
K +L + A + G ES +E DDS+L P Y+ +++K E
Sbjct: 132 DMLEKRKIQRELAKRAEQIEDINNTGTESASEEGDDSLLITVVPVKSYKTSGKMKKNFED 191
Query: 214 AGDKFKEEK 222
+K +EEK
Sbjct: 192 L-EKEREEK 199
Score = 33.1 bits (74), Expect = 0.53
Identities = 69/343 (20%), Positives = 138/343 (40%), Gaps = 60/343 (17%)
Query: 64 LDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLG 123
L+ +QE K + +E+ K+ +E R E EARR+ + E T+++ + G
Sbjct: 254 LERQRQENRKKQAEEEARKRLEEEKRAFE------EARRQMVNEDEENQDTAKIFK---G 304
Query: 124 ELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALSQGV 183
G +K S E+ + + ++ EEA + ++ ++ ++ + +
Sbjct: 305 YRPGKLKLSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNM-------VVDDDS 357
Query: 184 ESVKKEIDDSVLGQTGPYRRPQRLR-KRTEFAGDKFKEEK--VFEPNEEALGVVLHKDSK 240
+ K I L P +L E K +EEK E + L + + +
Sbjct: 358 PEMYKTISQEFL-------TPGKLEINFEELLKQKMEEEKRRTEEERKHKLEMEKQEFEQ 410
Query: 241 WYQQWKDFKENNVVF--NRFFEMKMKYDESDNAFIRASRALTDKVTDLLGGLFSKTEMSE 298
Q+ + +E N F +R +E +K S + + ++ +K+ G S+ E+ +
Sbjct: 411 LRQEMGEEEEENETFGLSREYEELIKLKRSGSIQAKNLKSKFEKI-----GQLSEKEIQK 465
Query: 299 VLTEILRVDPAFDKDRFLKQCEN-------DIIP-NVLEAMISGELDILKDWCYEATYSQ 350
+ E A D + ++ EN D+ P EA + ++++ +A + Q
Sbjct: 466 KIEEERARRRAIDLEIKEREAENFHEEDDVDVRPARKSEAPFTHKVNM------KARFEQ 519
Query: 351 LA--------HPIQQAKALGLQFHSRILDIDNVDLAMGKMMEQ 385
+A I++ K L +QF R +D A+ K E+
Sbjct: 520 MAKAREEEEQRRIEEQKLLRMQFEQR-----EIDAALQKKREE 557
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 38.1 bits (87), Expect = 0.016
Identities = 42/174 (24%), Positives = 82/174 (47%), Gaps = 18/174 (10%)
Query: 64 LDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTI----ESETVRTSEVLR 119
L+ +K+E ++E +E IK+ +++ L+ + L++ R++ T E E T +
Sbjct: 1964 LEILKKEY--DQEREEKIKQEQEDLE-LKHNSTLKQLMREFNTQLAQKEQELEMTIKETI 2020
Query: 120 KKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRAL 179
K E+ + ES H+ + L +KI E ++ +TAK+ E + E++ TA R L
Sbjct: 2021 NKAQEVEAELLES-HQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM--TAKVRDL 2077
Query: 180 SQGVESVKKEIDDSVLGQTGPYR--------RPQRLRKRTEFAGDKFKEEKVFE 225
+E ++K+ + + P + Q +K T + K KE++ E
Sbjct: 2078 QTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFRE 2131
Score = 34.3 bits (77), Expect = 0.24
Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 16/120 (13%)
Query: 60 LSGLLDNVKQELAKNKEMKESIKK-----FRDEARRLEESDVLQEARRKYKTIESETV-- 112
++ L +KQ + +E++E +K F + + L + +EARRK K E +
Sbjct: 384 IAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKT 443
Query: 113 --RTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKL 170
+TSE R L + VK+ + +V K K E+ AK K + +++ ++L
Sbjct: 444 IEKTSEEERISLQQELSRVKQEVVDVMK-------KSSEEQIAKLQKLHEKELARKEQEL 496
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 38.1 bits (87), Expect = 0.016
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 21/131 (16%)
Query: 64 LDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLG 123
++++K + AK KE++KK+ E R+LEE+ L AR++ E E V L +L
Sbjct: 852 IEDLKGDEAK---AKETLKKYEGEIRQLEEA--LVHARKE----EKEAVSARRALENELE 902
Query: 124 ELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALSQGV 183
G + ++ E + L K+KE E+ + + E ++ LG+T +
Sbjct: 903 AAQGNLSQTTQE--QKQLSEKLKEESEQKEQLRRLKNEMENERWH-LGKT---------I 950
Query: 184 ESVKKEIDDSV 194
E ++KE+ D V
Sbjct: 951 EKLQKEMADIV 961
>gi|120587019 zinc finger protein 318 [Homo sapiens]
Length = 2279
Score = 38.1 bits (87), Expect = 0.016
Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 12/164 (7%)
Query: 69 QELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGELTGT 128
++ K + E KK+ DE EE L +E+E R SE+ RK
Sbjct: 1152 EQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSELKRK-------- 1203
Query: 129 VKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKG---GEKLGRTAAFRALSQGVES 185
+ E E K + +KE V+E K +++ + +S+G EK Q E
Sbjct: 1204 LSEKPKEEKKEKKAKAVKE-VKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEE 1262
Query: 186 VKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEE 229
VKKE S +++P++ +++ +E++ E +++
Sbjct: 1263 VKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKD 1306
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 37.4 bits (85), Expect = 0.028
Identities = 39/171 (22%), Positives = 80/171 (46%), Gaps = 21/171 (12%)
Query: 73 KNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGELTGTVKES 132
K++ K + K +++ + + + +L+EARR+ + + + + LRKK + ++E+
Sbjct: 787 KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKK-DDRIEELEEA 845
Query: 133 LHEVSKSDLGRKIKEGVEEAAKT-AKQSAESVSKGGEKLGRTAAFRALSQGVESVKKEID 191
L E + R++ EE+A+T A++ E + EK + Q +ES+K ++
Sbjct: 846 LRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEK---------VKQELESMKAKLS 896
Query: 192 DS--VLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEA-LGVVLHKDS 239
+ L + + R +R E+V E +EA L + KD+
Sbjct: 897 STQQSLAEKETHLTNLRAERRKHL-------EEVLEMKQEALLAAISEKDA 940
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 37.4 bits (85), Expect = 0.028
Identities = 39/171 (22%), Positives = 80/171 (46%), Gaps = 21/171 (12%)
Query: 73 KNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLGELTGTVKES 132
K++ K + K +++ + + + +L+EARR+ + + + + LRKK + ++E+
Sbjct: 759 KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKK-DDRIEELEEA 817
Query: 133 LHEVSKSDLGRKIKEGVEEAAKT-AKQSAESVSKGGEKLGRTAAFRALSQGVESVKKEID 191
L E + R++ EE+A+T A++ E + EK + Q +ES+K ++
Sbjct: 818 LRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEK---------VKQELESMKAKLS 868
Query: 192 DS--VLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEA-LGVVLHKDS 239
+ L + + R +R E+V E +EA L + KD+
Sbjct: 869 STQQSLAEKETHLTNLRAERRKHL-------EEVLEMKQEALLAAISEKDA 912
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.0 bits (84), Expect = 0.037
Identities = 55/234 (23%), Positives = 103/234 (44%), Gaps = 24/234 (10%)
Query: 64 LDNVKQELAKNKEMKESIKKFR-DEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKL 122
+ ++KQE+ K +KE I + ++A++L + +QE + K E + VL +K
Sbjct: 831 VQDLKQEI---KALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKE 887
Query: 123 GELTGTVK--ESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALS 180
+L T K + L E ++S +K V+E A+ + A S S+ E
Sbjct: 888 KDLANTGKWLQDLQEENES-----LKAHVQEVAQHNLKEASSASQFEELEIVLKEKENEL 942
Query: 181 QGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKV-----FEPNEEALGVVL 235
+ +E++ KE + + +T + Q K + ++ K++ F P+EE L V+
Sbjct: 943 KRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVIS 1002
Query: 236 HKDSKWYQQW------KDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKV 283
++ + W KD E+ N +++ K E+ A + L DKV
Sbjct: 1003 EREKEISGLWNELDSLKDAVEHQRKKNN--DLREKNWEAMEALASTEKMLQDKV 1054
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.0 bits (84), Expect = 0.037
Identities = 55/234 (23%), Positives = 103/234 (44%), Gaps = 24/234 (10%)
Query: 64 LDNVKQELAKNKEMKESIKKFR-DEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKL 122
+ ++KQE+ K +KE I + ++A++L + +QE + K E + VL +K
Sbjct: 831 VQDLKQEI---KALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKE 887
Query: 123 GELTGTVK--ESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFRALS 180
+L T K + L E ++S +K V+E A+ + A S S+ E
Sbjct: 888 KDLANTGKWLQDLQEENES-----LKAHVQEVAQHNLKEASSASQFEELEIVLKEKENEL 942
Query: 181 QGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKV-----FEPNEEALGVVL 235
+ +E++ KE + + +T + Q K + ++ K++ F P+EE L V+
Sbjct: 943 KRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVIS 1002
Query: 236 HKDSKWYQQW------KDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKV 283
++ + W KD E+ N +++ K E+ A + L DKV
Sbjct: 1003 EREKEISGLWNELDSLKDAVEHQRKKNN--DLREKNWEAMEALASTEKMLQDKV 1054
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 37.0 bits (84), Expect = 0.037
Identities = 41/190 (21%), Positives = 93/190 (48%), Gaps = 18/190 (9%)
Query: 56 RKGFLSGLLDNVKQELA-KNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRT 114
R+ L+ L +K+E+A +++E++ ++++ + +L S +Q+A + + +E+E +
Sbjct: 493 RERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRS--MQDATQDHAVLEAERQKM 550
Query: 115 SEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTA 174
S ++R EL T +E+ H S + +K KE + + Q + E+LG
Sbjct: 551 SALVRGLQRELEETSEETGHWQS---MFQKNKEDLRATKQELLQLRMEKEEMEEELG--- 604
Query: 175 AFRALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEPNEEALGVV 234
+ +E +++E++ + G R+ + L+K ++ KE + ++E G
Sbjct: 605 ------EKIEVLQRELEQA-RASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAG-- 655
Query: 235 LHKDSKWYQQ 244
H+D + +Q
Sbjct: 656 RHRDRELEKQ 665
>gi|40805862 tumor protein D52-like 2 isoform f [Homo sapiens]
Length = 186
Score = 36.6 bits (83), Expect = 0.048
Identities = 33/144 (22%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Query: 57 KGFLSGLLDNVKQE--LAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRT 114
KG LS + +V + +A E + + +E R E + V +E + + ++
Sbjct: 15 KGLLSDSMTDVPVDTGVAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHC 74
Query: 115 SEVLRK----KLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKG-GEK 169
E+ R+ LGEL + S H+V S +K +E + +A + + +V K
Sbjct: 75 GELKRRLGLSTLGELKQNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRK 134
Query: 170 LG---RTAAFRALSQGVESVKKEI 190
LG +A F++ V ++K ++
Sbjct: 135 LGDMRNSATFKSFEDRVGTIKSKV 158
>gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens]
Length = 840
Score = 36.2 bits (82), Expect = 0.063
Identities = 62/320 (19%), Positives = 128/320 (40%), Gaps = 55/320 (17%)
Query: 101 RRKYKTIESETVRTSEV-LRKKLGELTGTVKES----LHEVSKSDLGRKIKEGVEEAAKT 155
+ + + +S++ +TS+ +++K+ E+ KE ++EV S G+K K + A
Sbjct: 157 KEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACAC 216
Query: 156 AKQSAESVSKGGEKLGRTAAFRALSQGVESVKKEIDDSVLGQTGPYRR------------ 203
+ Q + K +K R + + E + ++ SV+ + ++
Sbjct: 217 SSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTL 276
Query: 204 --------PQRLRKRTEFAGDKFKEEKVFEPNEEALG------VVLHKDSKWYQQWKDFK 249
P++ E AG K K + + EE G V + K+S + K+ K
Sbjct: 277 PKSPQPSVPEQSDNELEQAG-KSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEK 335
Query: 250 ENNVVFNRF-FEMKMKYDESDNAFIRASRALTDKVTD----LLGGLFSKTEMSEVLTEIL 304
+ E ++ + + N ++ +R + T +L G+ S + + T+I
Sbjct: 336 PTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKI- 394
Query: 305 RVDPAFDKDRFLKQCENDIIPNVLEAMISGELDILKDWCYEATYSQLAHPIQQAKALGLQ 364
+F N + N L++ +S +L +L+ + ++ HP+ Q+ LG +
Sbjct: 395 ------KLSKF-----NSVQHNKLDSQVSPKLGLLRT-SFSPPALEMHHPVTQSTFLGTK 442
Query: 365 FHSRILDIDNVDLAMGKMME 384
H R N+ KM E
Sbjct: 443 LHDR-----NITCQQEKMKE 457
>gi|222537714 taxilin beta [Homo sapiens]
Length = 684
Score = 35.4 bits (80), Expect = 0.11
Identities = 60/296 (20%), Positives = 121/296 (40%), Gaps = 33/296 (11%)
Query: 63 LLDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKL 122
LL + ++ K K+ + AR ES + +E +R KT++ E ++ + +K
Sbjct: 185 LLQKKQVQIQKEKDQLQGEHSRAILARSKLES-LCRELQRHNKTLKEEALQRAREEEEKR 243
Query: 123 GELTGTVKESLHEV-----SKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGRTAAFR 177
E+T + +L ++ +S+ K+ + E A+ K + E L + R
Sbjct: 244 KEITSHFQSTLTDIQGQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHR 303
Query: 178 ALSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEF----AGDKFKEEKVFEPNEEALGV 233
L Q + K E ++ + +R ++ E+ A + + KV + E L
Sbjct: 304 ELQQKLVDAKLEQAQEMMKEA-----EERHKREKEYLLNQAAEWKLQAKVLKEQETVLQA 358
Query: 234 VLHKDSKWYQQWKD-FKENNVVFNRFFE------MKMKYDESDNA-----FIRASRALTD 281
L S +++++ ++N VF F + KMK E D A F ++AL D
Sbjct: 359 QLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLD 418
Query: 282 KVTDLLGGLFSKTEMSEVLTEILRVDPAFDKDRFLKQCENDIIPNVLEAMISGELD 337
+ + E ++++ + R L++ N++ + +A IS + D
Sbjct: 419 MIEE------KALRAKEYECFVMKIGRLENLCRALQEERNELHKKIRDAEISEKDD 468
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,826,541
Number of Sequences: 37866
Number of extensions: 685538
Number of successful extensions: 2957
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 239
Number of HSP's that attempted gapping in prelim test: 2791
Number of HSP's gapped (non-prelim): 447
length of query: 452
length of database: 18,247,518
effective HSP length: 106
effective length of query: 346
effective length of database: 14,233,722
effective search space: 4924867812
effective search space used: 4924867812
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.