Guide to the Human Genome
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Search of human proteins with 33620759

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33620759 LRP2 binding protein [Homo sapiens]
         (347 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33620759 LRP2 binding protein [Homo sapiens]                       711   0.0  
gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens]             61   1e-09
gi|151301150 sel-1 suppressor of lin-12-like 2 [Homo sapiens]          55   1e-07
gi|217330658 hypothetical protein LOC9812 [Homo sapiens]               54   2e-07
gi|217330656 hypothetical protein LOC9812 [Homo sapiens]               54   2e-07
gi|154689719 hypothetical protein LOC23231 [Homo sapiens]              40   0.003
gi|12751491 hypothetical protein LOC65260 [Homo sapiens]               38   0.015
gi|115430239 spectrin, beta, non-erythrocytic 4 isoform sigma5 [...    33   0.29 
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [...    33   0.29 
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ...    33   0.38 
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ...    33   0.38 
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ...    33   0.38 
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ...    33   0.38 
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    33   0.49 
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    33   0.49 
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]                 32   0.84 
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]         32   1.1  
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom...    32   1.1  
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 31   1.9  
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform...    30   2.4  
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform...    30   2.4  
gi|93102364 SWAP-70 protein [Homo sapiens]                             30   3.2  
gi|57164948 solute carrier family 30 (zinc transporter), member ...    30   3.2  
gi|11036654 protocadherin beta 13 precursor [Homo sapiens]             30   3.2  
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]           29   5.4  
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       29   7.1  
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]       29   7.1  
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       29   7.1  
gi|22749211 transmembrane and tetratricopeptide repeat containin...    29   7.1  
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap...    29   7.1  

>gi|33620759 LRP2 binding protein [Homo sapiens]
          Length = 347

 Score =  711 bits (1834), Expect = 0.0
 Identities = 347/347 (100%), Positives = 347/347 (100%)

Query: 1   MKLTSEKLPKNPFYASVSQYAAKNQKFFQWKKEKTDYTHANLVDKALQLLKERILKGDTL 60
           MKLTSEKLPKNPFYASVSQYAAKNQKFFQWKKEKTDYTHANLVDKALQLLKERILKGDTL
Sbjct: 1   MKLTSEKLPKNPFYASVSQYAAKNQKFFQWKKEKTDYTHANLVDKALQLLKERILKGDTL 60

Query: 61  AYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATYQLGVMYYDGLGTTLDAEKGVDYMKKI 120
           AYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATYQLGVMYYDGLGTTLDAEKGVDYMKKI
Sbjct: 61  AYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATYQLGVMYYDGLGTTLDAEKGVDYMKKI 120

Query: 121 LDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLG 180
           LDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLG
Sbjct: 121 LDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLG 180

Query: 181 LYYSTKEPKELEKAFYWHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAER 240
           LYYSTKEPKELEKAFYWHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAER
Sbjct: 181 LYYSTKEPKELEKAFYWHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAER 240

Query: 241 GNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPMIAQVTDCLPEFIGRGMAMAS 300
           GNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPMIAQVTDCLPEFIGRGMAMAS
Sbjct: 241 GNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPMIAQVTDCLPEFIGRGMAMAS 300

Query: 301 FYHARCLQLGLGITRDETTAKHYYSKACRLNPALADELHSLLIRQRI 347
           FYHARCLQLGLGITRDETTAKHYYSKACRLNPALADELHSLLIRQRI
Sbjct: 301 FYHARCLQLGLGITRDETTAKHYYSKACRLNPALADELHSLLIRQRI 347


>gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens]
          Length = 794

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 41/124 (33%), Positives = 68/124 (54%), Gaps = 8/124 (6%)

Query: 135 AAYNLGRAY-YEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLGLYYSTKE---PKE 190
           A   LG+ + + G+GV+++++ A   + +AA+ GN  A     + LG  YS      P+ 
Sbjct: 375 AQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHA----MAFLGKMYSEGSDIVPQS 430

Query: 191 LEKAFYWHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAERGNVYAQGNLV 250
            E A ++  +A   GN   Q  LG+ YLYG+G++ + + AL+  ++AAE+G V  Q  L 
Sbjct: 431 NETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLG 490

Query: 251 EYYY 254
             YY
Sbjct: 491 SMYY 494



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 53/183 (28%), Positives = 90/183 (49%), Gaps = 16/183 (8%)

Query: 76  EEALEQFEEIKEK-DHQATYQLGVMY-YDGLGTTLDAEKGVDYMKKILDSPCPKARHLKF 133
           E+ ++ ++ + EK D QA   LG ++ + G G   + ++  DY    L +    +  + F
Sbjct: 358 EDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFN--LAANAGNSHAMAF 415

Query: 134 AAAYNLGRAYYEGKG-VKRSNEEAERLWLIAADNGNPKASVKAQSMLGLYYSTKEPKEL- 191
                LG+ Y EG   V +SNE A   +  AAD GNP      QS LG+ Y      ++ 
Sbjct: 416 -----LGKMYSEGSDIVPQSNETALHYFKKAADMGNPVG----QSGLGMAYLYGRGVQVN 466

Query: 192 -EKAFYWHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAERGNVYAQGNLV 250
            + A  +  +A   G ++ Q  LG MY  G G+++D + AL+    A++ G++ A  NL 
Sbjct: 467 YDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLA 526

Query: 251 EYY 253
           + +
Sbjct: 527 QMH 529



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 47/193 (24%), Positives = 80/193 (41%), Gaps = 16/193 (8%)

Query: 56  KGDTLAYFLRGQLYFEEGW-----YEEALEQFE-EIKEKDHQATYQLGVMYYDGLGTTLD 109
           KGD  A    GQL+   G      ++ A + F       +  A   LG MY +G      
Sbjct: 370 KGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQ 429

Query: 110 A-EKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGN 168
           + E  + Y KK  D   P  +         LG AY  G+GV+ + + A + +  AA+ G 
Sbjct: 430 SNETALHYFKKAADMGNPVGQS-------GLGMAYLYGRGVQVNYDLALKYFQKAAEQGW 482

Query: 169 PKASVKAQSMLGLYYSTKEPKELEKAFYWHSEACGNGNLESQGALGLMYLYGQGIRQDTE 228
               ++  SM   Y      ++ ++A  + + A   G++ +   L  M+  G G+ +   
Sbjct: 483 VDGQLQLGSMY--YNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCH 540

Query: 229 AALQCLREAAERG 241
            A++  +   ERG
Sbjct: 541 TAVELFKNVCERG 553



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 28/109 (25%), Positives = 40/109 (36%), Gaps = 2/109 (1%)

Query: 137 YNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLGLYYSTKEPKELEKAFY 196
           Y  G     G   K    EA R    AA   + KA  +      L +    P+ ++ A  
Sbjct: 187 YQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVS--YALLFGDYLPQNIQAARE 244

Query: 197 WHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAERGNVYA 245
              +    G+ + Q ALG +Y  G G+      AL      A  GN+ A
Sbjct: 245 MFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIA 293



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 10/95 (10%)

Query: 92  ATYQLGVMYYDGLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKR 151
           A  +LG  ++ G GT       VDY    +       +     A +NLG  + +G G+K+
Sbjct: 629 ARIKLGDYHFYGFGTD------VDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQ 682

Query: 152 SNEEAERLWLIAADNGNPKASVK---AQSMLGLYY 183
               A+R + +AA+  +P A V    A   LG+ Y
Sbjct: 683 DIHLAKRFYDMAAE-ASPDAQVPVFLALCKLGVVY 716


>gi|151301150 sel-1 suppressor of lin-12-like 2 [Homo sapiens]
          Length = 688

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 69/278 (24%), Positives = 101/278 (36%), Gaps = 65/278 (23%)

Query: 96  LGVMYYDGLGTTLDAEKGVDYMKKILDS-----------PCPKAR--------------- 129
           LG  Y  G+    + E  + Y KK+ D            P  K R               
Sbjct: 221 LGYRYLSGINVLQNCEVALSYYKKVADYIADTFEKSEGVPVEKVRLTERPENLSSNSEIL 280

Query: 130 ------HLKFAAA-------YNLGRAYYEG-KGVKRSNEEAERLWLIAADNGNPKASVKA 175
                 + KF A         +LG+ +  G KG+ +   +A   +L AA  G    S  A
Sbjct: 281 DWDIYQYYKFLAERGDVQIQVSLGQLHLIGRKGLDQDYYKALHYFLKAAKAG----SANA 336

Query: 176 QSMLGLYY---STKEPKELEKAFYWHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQ 232
            + +G  Y   +   P+    AF + S A   GN      LGL+Y +G+G+  +   AL+
Sbjct: 337 MAFIGKMYLEGNAAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALK 396

Query: 233 CLREAAERGNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPMIAQVTDCLPEFI 292
             ++AAE+G   AQ  L   YY      K         DY        +A  +       
Sbjct: 397 YFQKAAEKGWPDAQFQLGFMYYSGSGIWK---------DYKLAFKYFYLASQS------- 440

Query: 293 GRGMAMASFYHARCLQLGLGITRDETTAKHYYSKACRL 330
             G  +A +Y A+    G G+ R   TA   Y   C L
Sbjct: 441 --GQPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 476



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 73/291 (25%), Positives = 111/291 (38%), Gaps = 49/291 (16%)

Query: 56  KGDTLAYFLRGQLYFEEGW----YEEALEQFEEIKEKDH-QATYQLGVMYYDGLGTTLDA 110
           KG+ +     G LYF        Y EAL+ F++  EK    A +QLG MYY G G   D 
Sbjct: 368 KGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDY 427

Query: 111 EKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPK 170
           +    Y      S  P        A Y L + Y  G GV RS   A  L+    + G+  
Sbjct: 428 KLAFKYFYLASQSGQP-------LAIYYLAKMYATGTGVVRSCRTAVELYKGVCELGH-- 478

Query: 171 ASVKAQSMLGLYYSTKEPKELEKAFYWHS--EACGNGNLESQGALGLMYLYGQGIRQDT- 227
               A+  L  Y++ K+  +++ +   ++     G    +S  A  L       + ++  
Sbjct: 479 ---WAEKFLTAYFAYKD-GDIDSSLVQYALLAEMGYEVAQSNSAFILESKKANILEKEKM 534

Query: 228 -EAALQCLREAAERGNVYAQGNLVEYYY-----KMKFFTKCVAFSKRIADYDEVHDIPMI 281
              AL     AA +GN +A+  + +Y+Y     K  + T    +S     Y         
Sbjct: 535 YPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATHYSIAANKYHN------- 587

Query: 282 AQVTDCLPEFIGRGMAMASFYHARCLQLGLGITRDETTAKHYYSKACRLNP 332
                          A A F  A   + GLGIT+D   A+  Y  A + +P
Sbjct: 588 ---------------AQAMFNLAYMYEHGLGITKDIHLARRLYDMAAQTSP 623



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 36/140 (25%), Positives = 60/140 (42%), Gaps = 6/140 (4%)

Query: 137 YNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLGLYYSTKEPKELEKAFY 196
           + +G    +    ++  EEA  L+  AAD GN KA  K      L +     + +  A  
Sbjct: 111 FKMGIKVLQQSKSQKQKEEAYLLFAKAADMGNLKAMEKMAD--ALLFGNFGVQNITAAIQ 168

Query: 197 WHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAERGNVYAQGNL-VEYYYK 255
            +      G+ ++Q ALG +  YG G+  D   AL      +  GN+ +Q  L   Y   
Sbjct: 169 LYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKALIYYTFGSAGGNMMSQMILGYRYLSG 228

Query: 256 MKFFTKC---VAFSKRIADY 272
           +     C   +++ K++ADY
Sbjct: 229 INVLQNCEVALSYYKKVADY 248


>gi|217330658 hypothetical protein LOC9812 [Homo sapiens]
          Length = 515

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 54/222 (24%), Positives = 102/222 (45%), Gaps = 16/222 (7%)

Query: 32  KEKTDYTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDH- 90
           +++ D +    +++A+  +++      ++A+   G    + G +  A   F++   + + 
Sbjct: 218 EKEQDKSKTLSLEEAVTSIQQLFQLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYS 277

Query: 91  QATYQLGVMYYDGLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVK 150
           +A Y  G+ +  G GT  D  K V Y +         A      A Y   R         
Sbjct: 278 KAQYNAGLCHEHGRGTPRDISKAVLYYQLA-------ASQGHSLAQYRYARCLLRDPASS 330

Query: 151 RSNEEAERLWLI--AADNGNPKASVKAQSMLGLYYSTKEPK-ELEKAFYWHSEACGNGNL 207
            + E    + L+  AAD+G  +A    Q+ LG+ + TKEP  + ++A  +   A  NG+ 
Sbjct: 331 WNPERQRAVSLLKQAADSGLREA----QAFLGVLF-TKEPYLDEQRAVKYLWLAANNGDS 385

Query: 208 ESQGALGLMYLYGQGIRQDTEAALQCLREAAERGNVYAQGNL 249
           +S+  LG+ Y  G G++++   AL+C +++A  GN  AQ  L
Sbjct: 386 QSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGNEAAQERL 427



 Score = 32.3 bits (72), Expect = 0.64
 Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 108 LDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNG 167
           LD ++ V Y+    ++   ++R       Y+LG  Y +G GV+R+  EA R +  +A  G
Sbjct: 367 LDEQRAVKYLWLAANNGDSQSR-------YHLGICYEKGLGVQRNLGEALRCYQQSAALG 419

Query: 168 NPKASVKAQSMLGLYYSTKEPKEL 191
           N  A  + +++  +  +   P +L
Sbjct: 420 NEAAQERLRALFSMGAAAPGPSDL 443


>gi|217330656 hypothetical protein LOC9812 [Homo sapiens]
          Length = 515

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 54/222 (24%), Positives = 102/222 (45%), Gaps = 16/222 (7%)

Query: 32  KEKTDYTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDH- 90
           +++ D +    +++A+  +++      ++A+   G    + G +  A   F++   + + 
Sbjct: 218 EKEQDKSKTLSLEEAVTSIQQLFQLSVSIAFNFLGTENMKSGDHTAAFSYFQKAAARGYS 277

Query: 91  QATYQLGVMYYDGLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVK 150
           +A Y  G+ +  G GT  D  K V Y +         A      A Y   R         
Sbjct: 278 KAQYNAGLCHEHGRGTPRDISKAVLYYQLA-------ASQGHSLAQYRYARCLLRDPASS 330

Query: 151 RSNEEAERLWLI--AADNGNPKASVKAQSMLGLYYSTKEPK-ELEKAFYWHSEACGNGNL 207
            + E    + L+  AAD+G  +A    Q+ LG+ + TKEP  + ++A  +   A  NG+ 
Sbjct: 331 WNPERQRAVSLLKQAADSGLREA----QAFLGVLF-TKEPYLDEQRAVKYLWLAANNGDS 385

Query: 208 ESQGALGLMYLYGQGIRQDTEAALQCLREAAERGNVYAQGNL 249
           +S+  LG+ Y  G G++++   AL+C +++A  GN  AQ  L
Sbjct: 386 QSRYHLGICYEKGLGVQRNLGEALRCYQQSAALGNEAAQERL 427



 Score = 32.3 bits (72), Expect = 0.64
 Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 108 LDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNG 167
           LD ++ V Y+    ++   ++R       Y+LG  Y +G GV+R+  EA R +  +A  G
Sbjct: 367 LDEQRAVKYLWLAANNGDSQSR-------YHLGICYEKGLGVQRNLGEALRCYQQSAALG 419

Query: 168 NPKASVKAQSMLGLYYSTKEPKEL 191
           N  A  + +++  +  +   P +L
Sbjct: 420 NEAAQERLRALFSMGAAAPGPSDL 443


>gi|154689719 hypothetical protein LOC23231 [Homo sapiens]
          Length = 1132

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 61/271 (22%), Positives = 107/271 (39%), Gaps = 57/271 (21%)

Query: 90  HQATYQLGVMYYDGLGTTLDAEKGVDYM------KKILDSPCPKARHLK----FAAAYNL 139
           H+A+Y L V Y  GL    D  +G+ Y        + L S     +H +    +   + L
Sbjct: 570 HKASYYLAVFYETGLNVPRDQLQGMLYSLVGGQGSERLSSMNLGYKHYQGIDNYPLDWEL 629

Query: 140 GRAYYEGKGVK----------------------------RSNEEAER-LWLI-AADNGNP 169
             AYY     K                            ++ E+ +  +WL   A  GN 
Sbjct: 630 SYAYYSNIATKTPLDQHTLQGDQAYVETIRLKDDEILKVQTKEDGDVFMWLKHEATRGNA 689

Query: 170 KASVKAQSMLGLYYSTKEPKELEKAFYWHSEACGNGNLESQGALGLMYLY------GQGI 223
            A  +   ML  +      K  E A  W+++    G LE++    L+Y Y      GQG+
Sbjct: 690 AAQQRLAQML-FWGQQGVAKNPEAAIEWYAK----GALETEDP-ALIYDYAIVLFKGQGV 743

Query: 224 RQDTEAALQCLREAAERGNVYAQGNLVEYYYKM-KFFTKCVAF---SKRIADYDEVHDIP 279
           +++   AL+ +++AA +G   A   L  YY+K  K + K   +   ++ + + D  +++ 
Sbjct: 744 KKNRRLALELMKKAASKGLHQAVNGLGWYYHKFKKNYAKAAKYWLKAEEMGNPDASYNLG 803

Query: 280 MIAQVTDCLPEFIGRGMAMASFYHARCLQLG 310
           ++  +    P   GR   +A  Y  +  Q G
Sbjct: 804 VL-HLDGIFPGVPGRNQTLAGEYFHKAAQGG 833



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 51/213 (23%), Positives = 91/213 (42%), Gaps = 26/213 (12%)

Query: 50  LKERILKGDTLAYFLRGQLYF--EEGWY---EEALEQFEE--IKEKDHQATYQLGVMYYD 102
           LK    +G+  A     Q+ F  ++G     E A+E + +  ++ +D    Y   ++ + 
Sbjct: 680 LKHEATRGNAAAQQRLAQMLFWGQQGVAKNPEAAIEWYAKGALETEDPALIYDYAIVLFK 739

Query: 103 GLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLI 162
           G G   +    ++ MKK       K  H    A   LG  Y++    K++  +A + WL 
Sbjct: 740 GQGVKKNRRLALELMKKAAS----KGLH---QAVNGLGWYYHK---FKKNYAKAAKYWLK 789

Query: 163 AADNGNPKAS--VKAQSMLGLYYSTKEPKELEKAFYWHSEACGNGNLESQGALGLMYLYG 220
           A + GNP AS  +    + G++       +     Y+H  A G G++E      L Y+ G
Sbjct: 790 AEEMGNPDASYNLGVLHLDGIFPGVPGRNQTLAGEYFHKAAQG-GHMEGTLWCSLYYITG 848

Query: 221 --QGIRQDTEAALQCLREAAER----GNVYAQG 247
             +   +D E A+   +  AE+    G+V  +G
Sbjct: 849 NLETFPRDPEKAVVWAKHVAEKNGYLGHVIRKG 881


>gi|12751491 hypothetical protein LOC65260 [Homo sapiens]
          Length = 231

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 37/159 (23%), Positives = 66/159 (41%), Gaps = 9/159 (5%)

Query: 86  KEKDHQ-ATYQLGVMYYDGLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYY 144
           +E  H  + Y+LG  Y  G G      K      +     C K      AA +N+G   +
Sbjct: 63  EENQHSDSCYKLGAHYVTGKGGLTQDLKAA---ARCFLMACEKPGKKSIAACHNVGLLAH 119

Query: 145 EGKGVKRSNEE---AERLWLIAADNGNPKASVKAQSMLGLYYSTKEPKELEKAFYWHSEA 201
           +G+  +    +   A   +  A D G   +     +M  L  +   PK+++ A  +  +A
Sbjct: 120 DGQVNEDGQPDLGKARDYYTRACDGGYTSSCFNLSAMF-LQGAPGFPKDMDLACKYSMKA 178

Query: 202 CGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAER 240
           C  G++ +      MY  G G+ +D EA  + L+  A++
Sbjct: 179 CDLGHIWACANASRMYKLGDGVDKD-EAKAEVLKNRAQQ 216


>gi|115430239 spectrin, beta, non-erythrocytic 4 isoform sigma5
           [Homo sapiens]
          Length = 678

 Score = 33.5 bits (75), Expect = 0.29
 Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 23/145 (15%)

Query: 61  AYFLRGQLYFE----EGWY-EEALEQFEEIKEKDHQATYQLGVMYYDGLGTTLDAEKGVD 115
           A F   Q YF+    E W  E+ L    E K KD Q+T QL       L   L  E+GV+
Sbjct: 295 AAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQL-------LKKHLQLEQGVE 347

Query: 116 YMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKASVKA 175
             ++ +     + R L       L   + + + + R   + +RL++   + G  +  V  
Sbjct: 348 NYEESIAQLSRQCRAL-------LEMGHPDSEQISRRQSQVDRLYVALKELGEER-RVAL 399

Query: 176 QSMLGLYYSTKEPKELEKAFYWHSE 200
           +    LY  +++  ELE   +W +E
Sbjct: 400 EQQYWLYQLSRQVSELE---HWIAE 421


>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
            sapiens]
          Length = 2564

 Score = 33.5 bits (75), Expect = 0.29
 Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 23/145 (15%)

Query: 61   AYFLRGQLYFE----EGWY-EEALEQFEEIKEKDHQATYQLGVMYYDGLGTTLDAEKGVD 115
            A F   Q YF+    E W  E+ L    E K KD Q+T QL       L   L  E+GV+
Sbjct: 1619 AAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQL-------LKKHLQLEQGVE 1671

Query: 116  YMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKASVKA 175
              ++ +     + R L       L   + + + + R   + +RL++   + G  +  V  
Sbjct: 1672 NYEESIAQLSRQCRAL-------LEMGHPDSEQISRRQSQVDRLYVALKELGEER-RVAL 1723

Query: 176  QSMLGLYYSTKEPKELEKAFYWHSE 200
            +    LY  +++  ELE   +W +E
Sbjct: 1724 EQQYWLYQLSRQVSELE---HWIAE 1745


>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
           sapiens]
          Length = 807

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 6/84 (7%)

Query: 23  KNQKFFQWKKEKTDYTHANLVDKALQLLKERIL-KGDTL-AYFLRGQLYFEEGWYEEALE 80
           KNQ      K  T + H  L+ +A++  KE +  K D + AY   GQ Y E G +E A E
Sbjct: 227 KNQPIAMLYKGLT-FFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATE 285

Query: 81  QFEE--IKEKDHQATYQL-GVMYY 101
            F++  +  ++H  T QL G+M Y
Sbjct: 286 SFQKALLLNQNHVQTLQLRGMMLY 309


>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
           sapiens]
          Length = 860

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 6/84 (7%)

Query: 23  KNQKFFQWKKEKTDYTHANLVDKALQLLKERIL-KGDTL-AYFLRGQLYFEEGWYEEALE 80
           KNQ      K  T + H  L+ +A++  KE +  K D + AY   GQ Y E G +E A E
Sbjct: 280 KNQPIAMLYKGLT-FFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATE 338

Query: 81  QFEE--IKEKDHQATYQL-GVMYY 101
            F++  +  ++H  T QL G+M Y
Sbjct: 339 SFQKALLLNQNHVQTLQLRGMMLY 362


>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
           sapiens]
          Length = 833

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 55/225 (24%), Positives = 85/225 (37%), Gaps = 38/225 (16%)

Query: 35  TDYTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATY 94
           +D  H NLV +A+        K D L    R +    E +   + +    + E    A Y
Sbjct: 356 SDDPHTNLVTEAI--------KNDHLRQMERERKAMAEKYIMTSAKLIAPVIETSFAAGY 407

Query: 95  QLGV-----MYYDGLGTTLDAEKGVDYMKK--------ILDSPCPKARHLKFAAAYNLGR 141
              V       Y  L   L+  K V Y+++        IL     K   +K AAA NL  
Sbjct: 408 DWCVEVVKASQYVELANDLEINKAVTYLRQKDYNQAVEILKVLEKKDSRVKSAAATNLSA 467

Query: 142 AYYEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLGLYYSTKEPKELEKAFYWHSEA 201
            YY GK   +++  A+    + +D  NP A     +      +     + EKA  ++ EA
Sbjct: 468 LYYMGKDFAQASSYAD--IAVNSDRYNPAALTNKGN------TVFANGDYEKAAEFYKEA 519

Query: 202 CGNGNLESQGALGLMYLYGQGIRQDTEAALQC-------LREAAE 239
             N +  ++    +   Y +  R D   AL C       LR +AE
Sbjct: 520 LRNDSSCTEALYNIGLTYEKLNRLD--EALDCFLKLHAILRNSAE 562


>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
           sapiens]
          Length = 824

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 55/225 (24%), Positives = 85/225 (37%), Gaps = 38/225 (16%)

Query: 35  TDYTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATY 94
           +D  H NLV +A+        K D L    R +    E +   + +    + E    A Y
Sbjct: 347 SDDPHTNLVTEAI--------KNDHLRQMERERKAMAEKYIMTSAKLIAPVIETSFAAGY 398

Query: 95  QLGV-----MYYDGLGTTLDAEKGVDYMKK--------ILDSPCPKARHLKFAAAYNLGR 141
              V       Y  L   L+  K V Y+++        IL     K   +K AAA NL  
Sbjct: 399 DWCVEVVKASQYVELANDLEINKAVTYLRQKDYNQAVEILKVLEKKDSRVKSAAATNLSA 458

Query: 142 AYYEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLGLYYSTKEPKELEKAFYWHSEA 201
            YY GK   +++  A+    + +D  NP A     +      +     + EKA  ++ EA
Sbjct: 459 LYYMGKDFAQASSYAD--IAVNSDRYNPAALTNKGN------TVFANGDYEKAAEFYKEA 510

Query: 202 CGNGNLESQGALGLMYLYGQGIRQDTEAALQC-------LREAAE 239
             N +  ++    +   Y +  R D   AL C       LR +AE
Sbjct: 511 LRNDSSCTEALYNIGLTYEKLNRLD--EALDCFLKLHAILRNSAE 553


>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 32.7 bits (73), Expect = 0.49
 Identities = 62/250 (24%), Positives = 97/250 (38%), Gaps = 35/250 (14%)

Query: 59   TLAYFLRGQLYFE-EGWYEEALEQFEEIKEKDHQ-----ATYQLGVMYYDGLGTTLDAEK 112
            T A   RG  Y E E W+  A+E F  +   DHQ       Y L + YYD    T+    
Sbjct: 1052 TDALLKRGLFYCENENWF-AAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTI---Y 1107

Query: 113  GVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKAS 172
             +  M K L    P  + L ++   N  +A     G+  +  E     L+A      K  
Sbjct: 1108 QIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLA------KVQ 1161

Query: 173  VKAQSMLGLYYSTKEPKE-LEKAFYWHSEACGNGNLESQGA-----LGLMYLYGQGIRQD 226
            +KA+        TKE  E L+KA    S +    +  +  A     LGL Y+    ++  
Sbjct: 1162 MKAK-------RTKEAVEVLKKALDASSHSDKGPDATTISADCLYNLGLCYMEEGNLQMT 1214

Query: 227  TEAALQCLREAAERGNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPMIAQVTD 286
             + A+  L  A        + + + +Y +   +TK       + DY  V  + + A  T 
Sbjct: 1215 YKLAITDLTTAISMD----KNSYIAFYNRALCYTKIRELQMALTDYGIV--LLLDATETV 1268

Query: 287  CLPEFIGRGM 296
             L  F+ RG+
Sbjct: 1269 KLNTFLNRGL 1278


>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 32.7 bits (73), Expect = 0.49
 Identities = 63/250 (25%), Positives = 97/250 (38%), Gaps = 35/250 (14%)

Query: 59   TLAYFLRGQLYFE-EGWYEEALEQFEEIKEKDHQ-----ATYQLGVMYYDGLGTTLDAEK 112
            T A   RG  Y E E W+  A+E F  +   DHQ       Y L + YYD    T+    
Sbjct: 1052 TDALLKRGLFYCENENWF-AAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTI---Y 1107

Query: 113  GVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKAS 172
             +  M K L    P  + L ++   N  +A     G+  +  E     L+A      K  
Sbjct: 1108 QIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLA------KVQ 1161

Query: 173  VKAQSMLGLYYSTKEPKE-LEKAF--YWHSEACGNGNLESQGA---LGLMYLYGQGIRQD 226
            +KA+        TKE  E L+KA     HS+   +    S      LGL Y+    ++  
Sbjct: 1162 MKAK-------RTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMT 1214

Query: 227  TEAALQCLREAAERGNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPMIAQVTD 286
             + A+  L  A        + + + +Y +   +TK       + DY  V  + + A  T 
Sbjct: 1215 YKLAITDLTTAISMD----KNSYIAFYNRALCYTKIRELQMALTDYGIV--LLLDATETV 1268

Query: 287  CLPEFIGRGM 296
             L  F+ RG+
Sbjct: 1269 KLNTFLNRGL 1278


>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
          Length = 1870

 Score = 32.0 bits (71), Expect = 0.84
 Identities = 32/122 (26%), Positives = 61/122 (50%), Gaps = 27/122 (22%)

Query: 48   QLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATYQLGVMYYDGLGTT 107
            Q LKE++ + + ++YF +G+++      E+A++  +E+ E     TY+  V  Y+GLG  
Sbjct: 1294 QELKEKLYQ-EIISYFDKGKMW------EKAIKLSKELAE-----TYESKVFDYEGLGNL 1341

Query: 108  LDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAY----------YEGKGVKRSNEEAE 157
            L  +K   + + I+ +  P+  +  FA  Y  G+ +          Y GK  +R  + + 
Sbjct: 1342 L--KKRASFYENIIKAMRPQPEY--FAVGY-YGQGFPSFLRNKIFIYRGKEYERREDFSL 1396

Query: 158  RL 159
            RL
Sbjct: 1397 RL 1398


>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
          Length = 2481

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 40/155 (25%), Positives = 63/155 (40%), Gaps = 20/155 (12%)

Query: 57  GDTLAYFLRGQLYFEEGWYEEALEQFEE-----IKEKDHQATYQ----LGVMYYDGLG-- 105
           G+  A+   G  +F +G Y EAL          +K KD +A       LG +Y   +G  
Sbjct: 272 GECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVY-TAIGDY 330

Query: 106 -TTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAA 164
              L + K    + K       +AR L      N+G  Y      + + +  E+   IA 
Sbjct: 331 PNALASHKQCVLLAKQSKDELSEARELG-----NMGAVYIAMGDFENAVQCHEQHLKIAK 385

Query: 165 DNGNPKASVKAQSMLGLYYSTKEPKELEKAFYWHS 199
           D GN +   +A S LG  Y  +  +  +KA  +H+
Sbjct: 386 DLGNKREEARAYSNLGSAYHYR--RNFDKAMSYHN 418


>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
            sapiens]
          Length = 1614

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 63/250 (25%), Positives = 96/250 (38%), Gaps = 35/250 (14%)

Query: 59   TLAYFLRGQLYFE-EGWYEEALEQFEEIKEKDHQ-----ATYQLGVMYYDGLGTTLDAEK 112
            T A   RG  Y E E W+  A+E F  +   DHQ       Y L + YYD    T+    
Sbjct: 1052 TDALLKRGLFYCENENWF-AAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTI---Y 1107

Query: 113  GVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKAS 172
             +  M K L    P  + L ++   N  +A     G+  +  E     L+A      K  
Sbjct: 1108 QIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLA------KVQ 1161

Query: 173  VKAQSMLGLYYSTKEPKE-LEKAF--YWHSEACGNGNLESQGA---LGLMYLYGQGIRQD 226
            +KA+        TKE  E L+KA     HS+   +    S      LGL Y+    ++  
Sbjct: 1162 MKAK-------RTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMT 1214

Query: 227  TEAALQCLREAAERGNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPMIAQVTD 286
             + A+  L  A        + +   +Y +   +TK       + DY  V  + + A  T 
Sbjct: 1215 YKLAITDLTTAISMD----KNSYTAFYNRALCYTKIRELQMALTDYGIV--LLLDATETV 1268

Query: 287  CLPEFIGRGM 296
             L  F+ RG+
Sbjct: 1269 KLNTFLNRGL 1278


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 7/72 (9%)

Query: 17   VSQYAAKNQKFFQWKKEKTDYTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYE 76
            ++QY  K Q F + KK+K ++ H  +V      L+      DTL   +R     +E  + 
Sbjct: 3600 LAQYDEKAQSFEEVKKKKMEFLHEQMV----HFLQSMDTAKDTLETIVREAEELDEAVF- 3654

Query: 77   EALEQFEEIKEK 88
              L  FEEI E+
Sbjct: 3655 --LTSFEEINER 3664


>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
           [Homo sapiens]
          Length = 438

 Score = 30.4 bits (67), Expect = 2.4
 Identities = 45/189 (23%), Positives = 74/189 (39%), Gaps = 35/189 (18%)

Query: 43  VDKALQLLKERILKGDTL--AYFLRGQLYFEEGWYEEALEQFEEI----KEKDHQATYQL 96
           +D A++     +   DT   AY  R Q Y +   YEEA+  +E++    K K+H+   + 
Sbjct: 254 LDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKN 313

Query: 97  GVM---------YYDGLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGK 147
             +         YY  LG  +D     D +KK       + R L      + G +    K
Sbjct: 314 AQLELKKSKRKDYYKILG--VDKNASEDEIKKAY-----RKRALMHHPDRHSGASAEVQK 366

Query: 148 GVKRSNEEAERLWLIAADNGNPKASVKAQS-----MLGLYYSTKEPKELEKAFY-----W 197
             ++  +E    + I +D   PK   +  S       G+     +P  + KAF+     +
Sbjct: 367 EEEKKFKEVGEAFTILSD---PKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGF 423

Query: 198 HSEACGNGN 206
             EA G GN
Sbjct: 424 SFEASGPGN 432


>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
           [Homo sapiens]
          Length = 494

 Score = 30.4 bits (67), Expect = 2.4
 Identities = 45/189 (23%), Positives = 74/189 (39%), Gaps = 35/189 (18%)

Query: 43  VDKALQLLKERILKGDTL--AYFLRGQLYFEEGWYEEALEQFEEI----KEKDHQATYQL 96
           +D A++     +   DT   AY  R Q Y +   YEEA+  +E++    K K+H+   + 
Sbjct: 310 LDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKN 369

Query: 97  GVM---------YYDGLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGK 147
             +         YY  LG  +D     D +KK       + R L      + G +    K
Sbjct: 370 AQLELRKSKRKDYYKILG--VDKNASEDEIKKAY-----RKRALMHHPDRHSGASAEVQK 422

Query: 148 GVKRSNEEAERLWLIAADNGNPKASVKAQS-----MLGLYYSTKEPKELEKAFY-----W 197
             ++  +E    + I +D   PK   +  S       G+     +P  + KAF+     +
Sbjct: 423 EEEKKFKEVGEAFTILSD---PKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGF 479

Query: 198 HSEACGNGN 206
             EA G GN
Sbjct: 480 SFEASGPGN 488


>gi|93102364 SWAP-70 protein [Homo sapiens]
          Length = 585

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 17  VSQYAAKNQKFFQWKKEKTDYTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYE 76
           + + ++K  +  +W  E+         +K  +L  +R+LK   L   +  QL   E   +
Sbjct: 454 LEEESSKRAELEKWHLEQQQAIQTTEAEKQ-ELENQRVLKEQALQEAME-QLEQLELERK 511

Query: 77  EALEQFEEIKEKDHQAT 93
           +ALEQ+EE+K+K   AT
Sbjct: 512 QALEQYEEVKKKLEMAT 528


>gi|57164948 solute carrier family 30 (zinc transporter), member 9
           [Homo sapiens]
          Length = 568

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 4/63 (6%)

Query: 69  YFEEGWYEEALEQFEEIKEKDHQATYQLGVMYYDGLGTTLDAEKGVDYMKKILDSPCPKA 128
           Y E+  +++ L++ +E+K  +   T+ L   + + +  TL AE  VD ++K L    P+ 
Sbjct: 505 YLEKQDFDQMLQEIQEVKTPEELETFML--KHGENIIDTLGAE--VDRLEKELKKRNPEV 560

Query: 129 RHL 131
           RH+
Sbjct: 561 RHV 563


>gi|11036654 protocadherin beta 13 precursor [Homo sapiens]
          Length = 798

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 3/60 (5%)

Query: 140 GRAYYE---GKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLGLYYSTKEPKELEKAFY 196
           GR Y E    K + R  E   RL L A D G+P  S  AQ  + +        E E+ FY
Sbjct: 189 GRKYPELVLDKALDREEEAELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFY 248


>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
          Length = 1564

 Score = 29.3 bits (64), Expect = 5.4
 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 7/82 (8%)

Query: 80  EQFEEIKEKDH-QATYQLGVMYYDGLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYN 138
           E++  I  KD     YQ  +  Y+    ++D +K  D  KK++D    + +HL+ A  ++
Sbjct: 85  EKYNHINAKDDLPGVYQKLLDLYE----SVDKQKWCDVCKKLVDLYYQEKKHLEVARTWH 140

Query: 139 LGRAYYEGKGVKRSNEEAERLW 160
                 + +G +  NEE  +LW
Sbjct: 141 KLIKTRQEQGAE--NEELHQLW 160


>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 28.9 bits (63), Expect = 7.1
 Identities = 18/86 (20%), Positives = 41/86 (47%)

Query: 37  YTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATYQL 96
           + H N ++  + LLK ++ + +      + Q+   E   +  L   EE+ EK++QA+ + 
Sbjct: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360

Query: 97  GVMYYDGLGTTLDAEKGVDYMKKILD 122
            ++  + + T   A + V+    + D
Sbjct: 361 QLVQKESMDTINHASQLVEQAHDMRD 386


>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 1823

 Score = 28.9 bits (63), Expect = 7.1
 Identities = 18/86 (20%), Positives = 41/86 (47%)

Query: 37  YTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATYQL 96
           + H N ++  + LLK ++ + +      + Q+   E   +  L   EE+ EK++QA+ + 
Sbjct: 308 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 367

Query: 97  GVMYYDGLGTTLDAEKGVDYMKKILD 122
            ++  + + T   A + V+    + D
Sbjct: 368 QLVQKESMDTINHASQLVEQAHDMRD 393


>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 28.9 bits (63), Expect = 7.1
 Identities = 18/86 (20%), Positives = 41/86 (47%)

Query: 37  YTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATYQL 96
           + H N ++  + LLK ++ + +      + Q+   E   +  L   EE+ EK++QA+ + 
Sbjct: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360

Query: 97  GVMYYDGLGTTLDAEKGVDYMKKILD 122
            ++  + + T   A + V+    + D
Sbjct: 361 QLVQKESMDTINHASQLVEQAHDMRD 386


>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
           [Homo sapiens]
          Length = 836

 Score = 28.9 bits (63), Expect = 7.1
 Identities = 12/23 (52%), Positives = 17/23 (73%)

Query: 66  GQLYFEEGWYEEALEQFEEIKEK 88
           G+LY E+G YEEAL  ++E  +K
Sbjct: 613 GKLYHEQGHYEEALSVYKEAIQK 635


>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
           sapiens]
          Length = 890

 Score = 28.9 bits (63), Expect = 7.1
 Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 89  DHQATYQLGVMYYDGLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKG 148
           D   TY+L   + + +G  L+ E+ V  ++ + + P P  R L+F   + +  A +    
Sbjct: 103 DPLLTYRLYDKFAEAVGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSA-- 160

Query: 149 VKRSNEEAERLWLIAADNGNPKASVKAQSMLG 180
             ++N  A  L ++ A N      ++A    G
Sbjct: 161 --QTNMHARNLAIVWAPNLLRSKDIEASGFNG 190


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,562,551
Number of Sequences: 37866
Number of extensions: 534795
Number of successful extensions: 1391
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1323
Number of HSP's gapped (non-prelim): 71
length of query: 347
length of database: 18,247,518
effective HSP length: 103
effective length of query: 244
effective length of database: 14,347,320
effective search space: 3500746080
effective search space used: 3500746080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press