Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 33356547

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33356547 minichromosome maintenance complex component 2
[Homo sapiens]
         (904 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33356547 minichromosome maintenance complex component 2 [Homo...  1793   0.0  
gi|33469919 minichromosome maintenance complex component 4 [Homo...   342   7e-94
gi|33469917 minichromosome maintenance complex component 4 [Homo...   342   7e-94
gi|23510448 minichromosome maintenance complex component 5 [Homo...   323   4e-88
gi|7427519 minichromosome maintenance complex component 6 [Homo ...   322   1e-87
gi|33469968 minichromosome maintenance complex component 7 isofo...   317   2e-86
gi|6631095 minichromosome maintenance complex component 3 [Homo ...   316   5e-86
gi|19923727 minichromosome maintenance complex component 8 isofo...   307   3e-83
gi|33469922 minichromosome maintenance complex component 7 isofo...   303   6e-82
gi|33469924 minichromosome maintenance complex component 8 isofo...   301   1e-81
gi|23397546 minichromosome maintenance complex component 9 [Homo...   145   2e-34
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             45   4e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    43   0.001
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    43   0.002
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora...    40   0.008
gi|17975763 myelin transcription factor 1 [Homo sapiens]               40   0.008
gi|16262452 cingulin [Homo sapiens]                                    40   0.013
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    39   0.017
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         39   0.017
gi|148746195 trichohyalin [Homo sapiens]                               39   0.022
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]     39   0.022
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]      39   0.022
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               39   0.029
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]            39   0.029
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              39   0.029
gi|149999615 variable charge, X-linked 3B [Homo sapiens]               39   0.029
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    38   0.037
gi|17136078 VGF nerve growth factor inducible precursor [Homo sa...    38   0.037
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        38   0.037
gi|6005757 chromatin-specific transcription elongation factor la...    38   0.049

>gi|33356547 minichromosome maintenance complex component 2 [Homo
           sapiens]
          Length = 904

 Score = 1793 bits (4643), Expect = 0.0
 Identities = 904/904 (100%), Positives = 904/904 (100%)

Query: 1   MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTE 60
           MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTE
Sbjct: 1   MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTE 60

Query: 61  GPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQR 120
           GPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQR
Sbjct: 61  GPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQR 120

Query: 121 DREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGH 180
           DREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGH
Sbjct: 121 DREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGH 180

Query: 181 SVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAR 240
           SVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAR
Sbjct: 181 SVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAR 240

Query: 241 EHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQL 300
           EHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQL
Sbjct: 241 EHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQL 300

Query: 301 HLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGP 360
           HLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGP
Sbjct: 301 HLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGP 360

Query: 361 FEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHN 420
           FEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHN
Sbjct: 361 FEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHN 420

Query: 421 NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFAS 480
           NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFAS
Sbjct: 421 NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFAS 480

Query: 481 IAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVS 540
           IAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVS
Sbjct: 481 IAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVS 540

Query: 541 SRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI 600
           SRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI
Sbjct: 541 SRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSI 600

Query: 601 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDIL 660
           HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDIL
Sbjct: 601 HEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDIL 660

Query: 661 CVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVL 720
           CVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVL
Sbjct: 661 CVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVL 720

Query: 721 KKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARI 780
           KKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARI
Sbjct: 721 KKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARI 780

Query: 781 HLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLV 840
           HLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLV
Sbjct: 781 HLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLV 840

Query: 841 AEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMI 900
           AEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMI
Sbjct: 841 AEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMI 900

Query: 901 LQQF 904
           LQQF
Sbjct: 901 LQQF 904


>gi|33469919 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score =  342 bits (878), Expect = 7e-94
 Identities = 256/826 (30%), Positives = 399/826 (48%), Gaps = 104/826 (12%)

Query: 2   AESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEG 61
           A++  S    SSP+QRRRG D        S+     + +SPG DL             + 
Sbjct: 21  AQTPRSEDARSSPSQRRRGED------STSTGELQPMPTSPGVDL-------------QS 61

Query: 62  PLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRD 121
           P  ++     L     +    AIP LD   +  L             +       +RQR 
Sbjct: 62  PAAQDV----LFSSPPQMHSSAIP-LDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVRQRP 116

Query: 122 REAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHS 181
                 LG  ++GL  D                     DG   E+++ S ++L    G  
Sbjct: 117 -----DLGSAQKGLQVDLQS------------------DGAAAEDIVASEQSL----GQK 149

Query: 182 VREW---VSMAGPRLEIHHRFKNFLRTHVD---SHGHNV--------FKERISDMCKENR 227
           +  W   V++A  +      F+ FL+  +D       NV        + +R+ ++     
Sbjct: 150 LVIWGTDVNVAACK----ENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGE 205

Query: 228 ESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNH-IHVRIS 286
             L VN E + + +  L   L   P E++  FD A  E+    YP  D I  H I VR  
Sbjct: 206 PFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYP--DSILEHQIQVRPF 263

Query: 287 HLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQE 346
           +    + +R+L    ++QLI  SG+V   + ++P++    + C  C          + + 
Sbjct: 264 NALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVE-MDRGRI 322

Query: 347 VKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSC 406
            +P  C  C +     +    +++ + Q I++QESP  + AG+ P +       DLVD  
Sbjct: 323 AEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKV 382

Query: 407 KPGDEIELTGIYHN-NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGE--------LT 457
           +PGD + +TGIY       +   +N   V+ T I   H  K D K   G          +
Sbjct: 383 QPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFS 442

Query: 458 DEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPG--GKHKVRG 515
           ++ V+++  LS+   I E++ +++APSIY HEDIK+G+ L LFGG  K+    G+ K R 
Sbjct: 443 EKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRA 502

Query: 516 DINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGA 575
           +IN+LLCGDPGT+KSQ L+Y+  +  R  +T+G+G+SAVGLTAYV + P +R+  L+ GA
Sbjct: 503 EINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGA 562

Query: 576 LVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
           LVL+D G+C IDEFDKMN+  R+ +HE MEQQ++SI+KAGI+  L AR +V+AAANPI  
Sbjct: 563 LVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIES 622

Query: 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEG 695
           +++P  T  EN+ L   ++SRFD++ ++ D  D   D  LA  +V  + +     +E   
Sbjct: 623 QWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEE--- 679

Query: 696 LANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESM 755
                            E L   VLK YI YA   + P+L++     + + Y D+RK   
Sbjct: 680 -----------------ELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGS 722

Query: 756 ATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLES 801
           + G +    R +ES+IR+AEAHA++ L + V   DV  A R+  E+
Sbjct: 723 SRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768


>gi|33469917 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score =  342 bits (878), Expect = 7e-94
 Identities = 256/826 (30%), Positives = 399/826 (48%), Gaps = 104/826 (12%)

Query: 2   AESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEG 61
           A++  S    SSP+QRRRG D        S+     + +SPG DL             + 
Sbjct: 21  AQTPRSEDARSSPSQRRRGED------STSTGELQPMPTSPGVDL-------------QS 61

Query: 62  PLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRD 121
           P  ++     L     +    AIP LD   +  L             +       +RQR 
Sbjct: 62  PAAQDV----LFSSPPQMHSSAIP-LDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVRQRP 116

Query: 122 REAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHS 181
                 LG  ++GL  D                     DG   E+++ S ++L    G  
Sbjct: 117 -----DLGSAQKGLQVDLQS------------------DGAAAEDIVASEQSL----GQK 149

Query: 182 VREW---VSMAGPRLEIHHRFKNFLRTHVD---SHGHNV--------FKERISDMCKENR 227
           +  W   V++A  +      F+ FL+  +D       NV        + +R+ ++     
Sbjct: 150 LVIWGTDVNVAACK----ENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGE 205

Query: 228 ESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNH-IHVRIS 286
             L VN E + + +  L   L   P E++  FD A  E+    YP  D I  H I VR  
Sbjct: 206 PFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYP--DSILEHQIQVRPF 263

Query: 287 HLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQE 346
           +    + +R+L    ++QLI  SG+V   + ++P++    + C  C          + + 
Sbjct: 264 NALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVE-MDRGRI 322

Query: 347 VKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSC 406
            +P  C  C +     +    +++ + Q I++QESP  + AG+ P +       DLVD  
Sbjct: 323 AEPSVCGRCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKV 382

Query: 407 KPGDEIELTGIYHN-NYDGSLNTANGFPVFATVILANHVAKKDNKVAVGE--------LT 457
           +PGD + +TGIY       +   +N   V+ T I   H  K D K   G          +
Sbjct: 383 QPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFS 442

Query: 458 DEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPG--GKHKVRG 515
           ++ V+++  LS+   I E++ +++APSIY HEDIK+G+ L LFGG  K+    G+ K R 
Sbjct: 443 EKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRA 502

Query: 516 DINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGA 575
           +IN+LLCGDPGT+KSQ L+Y+  +  R  +T+G+G+SAVGLTAYV + P +R+  L+ GA
Sbjct: 503 EINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGA 562

Query: 576 LVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGG 635
           LVL+D G+C IDEFDKMN+  R+ +HE MEQQ++SI+KAGI+  L AR +V+AAANPI  
Sbjct: 563 LVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIES 622

Query: 636 RYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEG 695
           +++P  T  EN+ L   ++SRFD++ ++ D  D   D  LA  +V  + +     +E   
Sbjct: 623 QWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEE--- 679

Query: 696 LANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESM 755
                            E L   VLK YI YA   + P+L++     + + Y D+RK   
Sbjct: 680 -----------------ELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGS 722

Query: 756 ATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLES 801
           + G +    R +ES+IR+AEAHA++ L + V   DV  A R+  E+
Sbjct: 723 SRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREA 768


>gi|23510448 minichromosome maintenance complex component 5 [Homo
           sapiens]
          Length = 734

 Score =  323 bits (828), Expect = 4e-88
 Identities = 235/741 (31%), Positives = 373/741 (50%), Gaps = 74/741 (9%)

Query: 194 EIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRES----LVVNYEDLAAREHVLAYFLP 249
           ++  RFK FLR +        F  +  D  K +       + V  EDLA+ +  LA +L 
Sbjct: 30  QLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLY 89

Query: 250 EAPAELLQIFDEAALEV---VLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLI 306
           + PAE LQ+ +EAA EV   V    P  + +   I V +        +RSL+   ++ L+
Sbjct: 90  KQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLV 149

Query: 307 RTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQE--VKPGSC-------PECQS 357
           +  G++ + + V  + + +   C  C   L         E    P  C       P+C  
Sbjct: 150 KIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCP- 208

Query: 358 AGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGI 417
             P+ +  ++    ++Q +++QE P  V  G +PR         L D   PG+ + + GI
Sbjct: 209 LDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGI 268

Query: 418 YHNNYDGSLNTANGFPVFATVILANHV--------AKKDNKVAVGELTDEDVKMITSLSK 469
           Y     G L T+ G       I ++++             +   G ++ ++ +    L+ 
Sbjct: 269 YSIKKFG-LTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAA 327

Query: 470 DQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTA 528
              + E I  SIAPSI+G  D+K+ +A  LFGG  K  P G  + RGDIN+L+ GDPGTA
Sbjct: 328 LPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTR-RGDINLLMLGDPGTA 386

Query: 529 KSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDE 588
           KSQ LK++EK S   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDE
Sbjct: 387 KSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDE 446

Query: 589 FDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVD 648
           FDKM + DR +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D
Sbjct: 447 FDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDET-KGEDNID 505

Query: 649 LTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPN 708
               I+SRFD++ +V+D  +  +D MLA+ V+  HV                    A+  
Sbjct: 506 FMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHV-------------------SALTQ 546

Query: 709 TYGVE-PLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLR-------KESMATGSI 760
           T  VE  +    LKK+I Y + +  P+L+    +K+   Y  +R       ++S    SI
Sbjct: 547 TQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSI 606

Query: 761 PITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFAR 820
           PITVR +E+++R+AEA +++ L+ +  E DV  A+R+   S +D        ++  T + 
Sbjct: 607 PITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDA-------ALSGTLSG 659

Query: 821 YLSF-RRDNNELLLFILKQLVAEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSA 879
              F  +++ E+L  I KQL       +R   G+Q     + +     K  +  IH +  
Sbjct: 660 VEGFTSQEDQEMLSRIEKQL------KRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQ 713

Query: 880 FYDSELFRMNKFSHDLKRKMI 900
                + R  +  H ++RK++
Sbjct: 714 L----MLRRGEIQHRMQRKVL 730


>gi|7427519 minichromosome maintenance complex component 6 [Homo
           sapiens]
          Length = 821

 Score =  322 bits (824), Expect = 1e-87
 Identities = 212/660 (32%), Positives = 343/660 (51%), Gaps = 87/660 (13%)

Query: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEA------- 251
           F +FL     S G   + +   ++ +  R +LVV++ DL      L+  + E        
Sbjct: 30  FLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPY 89

Query: 252 PAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311
               L+ F +   E+ LA            +V    LP   ++R L    +  L R SG 
Sbjct: 90  LCRALKTFVKDRKEIPLA---------KDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQ 140

Query: 312 VTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSC--PECQSAGPFEVNMEETI 369
           V     V P+L    + C  C  V+    + Q +  +P  C  P C +   F ++  ++ 
Sbjct: 141 VVRTHPVHPELVSGTFLCLDCQTVIRDV-EQQFKYTQPNICRNPVCANRRRFLLDTNKSR 199

Query: 370 YQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIY----------- 418
           + ++Q++RIQE+  ++  G +PRS + IL A+ V+S + GD+ + TG             
Sbjct: 200 FVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLST 259

Query: 419 ---HNNYDGSLNTANGFPV---------------FATVILANHVAKKDNKVAVGELTDED 460
                  +  ++  +G+                 +  V LA  VA  + +    EL DE+
Sbjct: 260 PGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEE 319

Query: 461 V--------------KMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKN 506
                          + +  +S+D+ +   +  S+ P+I+G++++KRG+ L LFGG PK 
Sbjct: 320 QTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKT 379

Query: 507 PGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVS 566
            G    +RGDINV + GDP TAKSQFLK++E+ S RA++T+G+ +SA GLTA V R   S
Sbjct: 380 TGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEES 439

Query: 567 REWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTV 626
            E+ +EAGAL+LAD GVC IDEFDKM+ +D+ +IHEAMEQQ+ISI+KAG+  +L AR ++
Sbjct: 440 HEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSI 499

Query: 627 IAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRH 686
           +AAANPI G YD S +  +N++L+ PI+SRFD+  ++ D  + V D  +AR +V  H   
Sbjct: 500 LAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLH--- 556

Query: 687 HPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKM 746
                        S  E ++   Y ++      +++Y+++A++   PK+++  +D + + 
Sbjct: 557 -------------SRIEESIDRVYSLDD-----IRRYLLFARQ-FKPKISKESEDFIVEQ 597

Query: 747 YSDLRK---ESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFI 803
           Y  LR+     +   S  ITVR +ESMIR++EA AR+H  D V    V  A R++ +S I
Sbjct: 598 YKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSII 657


>gi|33469968 minichromosome maintenance complex component 7 isoform
           1 [Homo sapiens]
          Length = 719

 Score =  317 bits (813), Expect = 2e-86
 Identities = 193/518 (37%), Positives = 299/518 (57%), Gaps = 42/518 (8%)

Query: 294 LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPG-SC 352
           +R +R   + +L+   G+VT  + V P++ +  Y C++C      +   Q+    P   C
Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCG--AETYQPIQSPTFMPLIMC 206

Query: 353 P--ECQ---SAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCK 407
           P  ECQ   S G   +    + +  +Q +++QE   +V  G +PRS   ++  +     +
Sbjct: 207 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ 266

Query: 408 PGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAK----KDNKVAVGELTDEDVKM 463
           PGD + +TGI+               +  T + A+ + K    +D++   GELT E+++ 
Sbjct: 267 PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQ 326

Query: 464 ITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCG 523
           I     ++   EK+ ASIAP IYGHED+K+ L L L GG  ++P G  K+RG+IN+ L G
Sbjct: 327 IA----EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGM-KIRGNINICLMG 381

Query: 524 DPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGV 583
           DPG AKSQ L YI++++ R+ +TTG+G+S VGLTA V R  VS E TLE GALVLAD+GV
Sbjct: 382 DPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGV 441

Query: 584 CLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTF 643
           C IDEFDKM + DRT+IHE MEQQ+ISI+KAGI+T+L ARC+++AAANP  GRY+P  + 
Sbjct: 442 CCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSL 501

Query: 644 SENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFV--VGSHVRHHPSNKEEEGLANGSA 701
            +N+ L   ++SRFD+L +++D  D   D  LA+ +  V  H R  PS            
Sbjct: 502 EQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQ----------- 550

Query: 702 AEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIP 761
                      EPL  +++++YI   +E+  P + +   D +   Y ++R+E+ A+    
Sbjct: 551 ----------FEPLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT 599

Query: 762 IT-VRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 798
            T  R + +++R++ A AR+ + D V ++DVN AIR+M
Sbjct: 600 YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 637


>gi|6631095 minichromosome maintenance complex component 3 [Homo
           sapiens]
          Length = 808

 Score =  316 bits (810), Expect = 5e-86
 Identities = 217/644 (33%), Positives = 339/644 (52%), Gaps = 42/644 (6%)

Query: 193 LEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAP 252
           +E+    +++L    D     +++ ++ ++  +N+  L+VN  DL  +    A  L    
Sbjct: 10  VELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNA 69

Query: 253 AELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEEL--RSLRQLHLNQLIRTSG 310
            E L  F  A  + V ++   Y +     +V +      + +  R+L    L+ ++   G
Sbjct: 70  FEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEG 129

Query: 311 VVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVK-PGSC---PECQSAGPFEVNME 366
           +VT C+ V P++    + C      +          V  P S     + +   P E    
Sbjct: 130 IVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYG 189

Query: 367 ETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSL 426
            ++Y+++Q I IQE P K  AG+LPRS D IL  DLVD  KPGD +++ G Y        
Sbjct: 190 LSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKG 249

Query: 427 NTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSK--DQQIGEKIFASIAPS 484
              +G   F TV++A +V K+ +K A    + ED+  I   SK   + I +++  S+APS
Sbjct: 250 GYTSG--TFRTVLIACNV-KQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPS 306

Query: 485 IYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAI 544
           I+GH+ +K+ +   L GG  ++      +RGDIN+LL GDP  AKSQ L+Y+   + RAI
Sbjct: 307 IHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAI 366

Query: 545 FTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAM 604
            TTG+G+S VGLTA V     + E  LEAGA+VLADRGV  IDEFDKM+D DRT+IHE M
Sbjct: 367 PTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVM 426

Query: 605 EQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVR 664
           EQ  ++I+KAGI   L ARC+V+AAANP+ GRYD   T  EN+ L + ++SRFD+L ++ 
Sbjct: 427 EQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIML 486

Query: 665 DTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAM---PN------------- 708
           D +DP QD  ++  V+  H    P  ++ + +  GSA +      PN             
Sbjct: 487 DQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYE 546

Query: 709 -----TYGVEPLPQEV-----LKKYIIYAKERVHPKLNQMDQDKVAKMYSDLR-KESMAT 757
                 +G +   +++     +KKYI  AK  + P L Q     +A+ YS LR ++SM++
Sbjct: 547 KHDNLLHGTKKKKEKMVSAAFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSS 605

Query: 758 GSI---PITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 798
            +    P+T R +E++IR+A AHA+  +   V   D   A+ ++
Sbjct: 606 DTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELV 649


>gi|19923727 minichromosome maintenance complex component 8 isoform
           1 [Homo sapiens]
          Length = 840

 Score =  307 bits (786), Expect = 3e-83
 Identities = 227/757 (29%), Positives = 372/757 (49%), Gaps = 88/757 (11%)

Query: 125 GRGLGRMR---------RGLLYDSDEEDEERPARKRRQVERATEDGEE-------DEEMI 168
           GRG GR R          G       E E RP   +   +R +E   +        + M 
Sbjct: 7   GRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQ 66

Query: 169 ESIENLEDLKGHSV--REWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKEN 226
            +++     KG  +   E  S + P +E    F+ F   H+D +     K+ I     E 
Sbjct: 67  STLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYD----KDEI-----ER 117

Query: 227 RESLVVNYEDLAAREHV------LAYFLPEAPAELLQIFDEAALEVVLAMYPKY------ 274
           + S++V++++L     V      +A  L +AP + L     A  +V+     ++      
Sbjct: 118 KGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQA 177

Query: 275 -DRITN---------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSM 324
            + ++N         HIH R+ +   + +L+++R  +  + I   G V   + + P  + 
Sbjct: 178 QEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTK 237

Query: 325 VKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEE---TIYQNYQRIRIQE- 380
           + + C  C  +   F     +   P  CP     G     +     T+  ++Q I+IQE 
Sbjct: 238 MAFLCAACGEIQS-FPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQEL 296

Query: 381 -SPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYH--NNYDGSLNTANGFPVFAT 437
            S  +  AGR+PR+ +  L+ DLVDSC PGD + +TGI    N  +GS N  N   +F  
Sbjct: 297 MSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNK-NDKCMFLL 355

Query: 438 VILANHVAKKDNKVAVG-----------ELTDEDVKMITSLSKDQQIGEKIFASIAPSIY 486
            I AN ++    +               E + +D+  I  +  ++ + + I  S+ P I+
Sbjct: 356 YIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIF 415

Query: 487 GHEDIKRGLALALFGGEPKNPGGKHKV--RGDINVLLCGDPGTAKSQFLKYIEKVSSRAI 544
           GHE +K GLALALFGG  K    K+++  RGD ++L+ GDPG  KSQ L+    V+ R +
Sbjct: 416 GHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGV 475

Query: 545 FTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAM 604
           +  G   +  GLT  + +   S ++ LEAGALVL D+G+C IDEFDKM +Q +  + EAM
Sbjct: 476 YVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAM 534

Query: 605 EQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVR 664
           EQQSIS++KAG+V SL AR ++IAAANP+GG Y+ + T SEN+ +   ++SRFD++ ++ 
Sbjct: 535 EQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILL 594

Query: 665 DTVDPVQDEMLARFVVG--------------SHVRHHPSNKEEEGLANGSAAEPAMPNTY 710
           DT +   D +L+  V+               + +    SN     + +       +    
Sbjct: 595 DTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVP 654

Query: 711 G--VEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIE 768
           G  ++P+P ++L+KYI YA++ V+P+L+      +   Y +LRK+S    S PIT R +E
Sbjct: 655 GETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLE 714

Query: 769 SMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDT 805
           S+IR+ EA AR+ LR+   ++D    + +M  S + T
Sbjct: 715 SLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGT 751


>gi|33469922 minichromosome maintenance complex component 7 isoform
           2 [Homo sapiens]
          Length = 543

 Score =  303 bits (775), Expect = 6e-82
 Identities = 180/459 (39%), Positives = 272/459 (59%), Gaps = 39/459 (8%)

Query: 352 CP--ECQ---SAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSC 406
           CP  ECQ   S G   +    + +  +Q +++QE   +V  G +PRS   ++  +     
Sbjct: 30  CPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIA 89

Query: 407 KPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAK----KDNKVAVGELTDEDVK 462
           +PGD + +TGI+               +  T + A+ + K    +D++   GELT E+++
Sbjct: 90  QPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELR 149

Query: 463 MITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLC 522
            I     ++   EK+ ASIAP IYGHED+K+ L L L GG  ++P G  K+RG+IN+ L 
Sbjct: 150 QIA----EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGM-KIRGNINICLM 204

Query: 523 GDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRG 582
           GDPG AKSQ L YI++++ R+ +TTG+G+S VGLTA V R  VS E TLE GALVLAD+G
Sbjct: 205 GDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQG 264

Query: 583 VCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLT 642
           VC IDEFDKM + DRT+IHE MEQQ+ISI+KAGI+T+L ARC+++AAANP  GRY+P  +
Sbjct: 265 VCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRS 324

Query: 643 FSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFV--VGSHVRHHPSNKEEEGLANGS 700
             +N+ L   ++SRFD+L +++D  D   D  LA+ +  V  H R  PS           
Sbjct: 325 LEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQ---------- 374

Query: 701 AAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI 760
                       EPL  +++++YI   +E+  P + +   D +   Y ++R+E+ A+   
Sbjct: 375 -----------FEPLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDA 422

Query: 761 PIT-VRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 798
             T  R + +++R++ A AR+ + D V ++DVN AIR+M
Sbjct: 423 TYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 461


>gi|33469924 minichromosome maintenance complex component 8 isoform
           2 [Homo sapiens]
          Length = 824

 Score =  301 bits (772), Expect = 1e-81
 Identities = 222/751 (29%), Positives = 367/751 (48%), Gaps = 92/751 (12%)

Query: 125 GRGLGRMR---------RGLLYDSDEEDEERPARKRRQVERATEDGEE-------DEEMI 168
           GRG GR R          G       E E RP   +   +R +E   +        + M 
Sbjct: 7   GRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQ 66

Query: 169 ESIENLEDLKGHSV--REWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKEN 226
            +++     KG  +   E  S + P +E    F+ F   H+D +     K+ I     E 
Sbjct: 67  STLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYD----KDEI-----ER 117

Query: 227 RESLVVNYEDLAAREHV------LAYFLPEAPAELLQIFDEAALEVVLAMYPKY------ 274
           + S++V++++L     V      +A  L +AP + L     A  +V+     ++      
Sbjct: 118 KGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQA 177

Query: 275 -DRITN---------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSM 324
            + ++N         HIH R+ +   + +L+++R  +  + I   G V   + + P  + 
Sbjct: 178 QEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTK 237

Query: 325 VKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEE---TIYQNYQRIRIQE- 380
           + + C  C  +   F     +   P  CP     G     +     T+  ++Q I+IQE 
Sbjct: 238 MAFLCAACGEIQS-FPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQEL 296

Query: 381 -SPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVI 439
            S  +  AGR+PR+ +  L+ DLVDSC PGD + +TGI   +     N+           
Sbjct: 297 MSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEANS----------- 345

Query: 440 LANHVAKKDNKVAVG-------ELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIK 492
           ++N   +K      G       E + +D+  I  +  ++ + + I  S+ P I+GHE +K
Sbjct: 346 ISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVK 405

Query: 493 RGLALALFGGEPKNPGGKHKV--RGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQG 550
            GLALALFGG  K    K+++  RGD ++L+ GDPG  KSQ L+    V+ R ++  G  
Sbjct: 406 AGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNT 465

Query: 551 ASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSIS 610
            +  GLT  + +   S ++ LEAGALVL D+G+C IDEFDKM +Q +  + EAMEQQSIS
Sbjct: 466 TTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSIS 524

Query: 611 ISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPV 670
           ++KAG+V SL AR ++IAAANP+GG Y+ + T SEN+ +   ++SRFD++ ++ DT +  
Sbjct: 525 LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH 584

Query: 671 QDEMLARFVVG--------------SHVRHHPSNKEEEGLANGSAAEPAMPNTYG--VEP 714
            D +L+  V+               + +    SN     + +       +    G  ++P
Sbjct: 585 HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP 644

Query: 715 LPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMA 774
           +P ++L+KYI YA++ V+P+L+      +   Y +LRK+S    S PIT R +ES+IR+ 
Sbjct: 645 IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT 704

Query: 775 EAHARIHLRDYVIEDDVNMAIRVMLESFIDT 805
           EA AR+ LR+   ++D    + +M  S + T
Sbjct: 705 EARARLELREEATKEDAEDIVEIMKYSMLGT 735


>gi|23397546 minichromosome maintenance complex component 9 [Homo
           sapiens]
          Length = 391

 Score =  145 bits (366), Expect = 2e-34
 Identities = 113/369 (30%), Positives = 183/369 (49%), Gaps = 37/369 (10%)

Query: 214 VFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEA----ALEVVLA 269
           + KER  D        +VVN   L      +  +    P+E+L IFD A    AL ++ +
Sbjct: 28  ILKERDEDA----HYPVVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRRSALTILQS 83

Query: 270 M-YPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVK-- 326
           +  P+   +  ++H RIS LP+  EL  +R+ H+ +  +  G   S TG + + S+VK  
Sbjct: 84  LSQPEAVSMKQNLHARISGLPVCPEL--VRE-HIPKT-KDVGHFLSVTGTVIRTSLVKVL 139

Query: 327 -----YNCNKCN--FVLGPFCQSQNQEVKPGSCPECQSAGPFE------VNMEETIYQNY 373
                Y CNKC   FV+    +      +P SCP  +S    +      ++   T  ++Y
Sbjct: 140 EFERDYMCNKCKHVFVIKADFEQYYTFCRPSSCPSLESCDSSKFTCLSGLSSSPTRCRDY 199

Query: 374 QRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFP 433
           Q I+IQE   +++ G +PRS   IL  DLVDSCK GD++ + GI    +           
Sbjct: 200 QEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQDVR--- 256

Query: 434 VFATVILANHVAKKDNKVAVGELTDEDVKMITS-----LSKDQQIGEK-IFASIAPSIYG 487
               ++L  +  + +N+ + G + DE+V+            D   G   I AS+ P ++G
Sbjct: 257 CEVEIVLKANYIQVNNEQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFG 316

Query: 488 HEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTT 547
              +K  +A+ L GG  +      +VRG+ ++LL GDPGT KSQFLKY  K++ R++ TT
Sbjct: 317 MYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTT 376

Query: 548 GQGASAVGL 556
           G G+++ G+
Sbjct: 377 GIGSTSAGI 385


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 47/175 (26%), Positives = 76/175 (43%), Gaps = 23/175 (13%)

Query: 11  ASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGE 70
           AS+PA        + S+P  +   + ++ +S G   P   +E+  LL  +  L  E+  +
Sbjct: 440 ASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDP---EEATRLLAEKRRLAREQREK 496

Query: 71  ELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGR 130
           E      ER+ R   EL+  + E LA      EE T  + E + R   ++ RE    L R
Sbjct: 497 E------ERERREQEELERQKREELA--QRVAEERTTRREEESRRLEAEQAREKEEQLQR 548

Query: 131 MRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENL-EDLKGHSVRE 184
                      + EER  R+R + ERA    EE+  + E  E + ++ + H  RE
Sbjct: 549 -----------QAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQRE 592


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 38/118 (32%), Positives = 48/118 (40%), Gaps = 7/118 (5%)

Query: 50   EDESEGLLGTEGPLE-EEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTAS 108
            E+E EG    EG  E EEE+GE   G G E       E +  E EG   D E   E    
Sbjct: 897  EEEGEGEGEEEGEGEGEEEEGE---GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEG 953

Query: 109  QREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166
            + E  E        E G G G    G   + +EE+ E    +    E   E+GE +EE
Sbjct: 954  EWEGEEEEGEGEGEEEGEGEGEEGEG---EGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 9/117 (7%)

Query: 50   EDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQ 109
            E+E EG    EG  E E +GEE  G+G E +     E +  E EG    + + E     +
Sbjct: 959  EEEGEG----EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGE 1014

Query: 110  REAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166
             E       + + E G G G    G     +EE EER      +  R   + EE+EE
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEG-----EEEGEEREKEGEGEENRRNREEEEEEE 1066



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 37/122 (30%), Positives = 52/122 (42%), Gaps = 13/122 (10%)

Query: 50   EDESEGLLGTEGPLEE-----EEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEE 104
            E+E EG    EG  EE     EE+GEE  G+G E +     E +  + EG   ++E   E
Sbjct: 905  EEEGEG----EGEEEEGEGKGEEEGEEGEGEGEEEE----GEGEGEDGEGEGEEEEGEWE 956

Query: 105  LTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEED 164
                + E       + + E G G G    G     +EE EE    +    E    +GEE+
Sbjct: 957  GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE 1016

Query: 165  EE 166
            EE
Sbjct: 1017 EE 1018



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 38/121 (31%), Positives = 52/121 (42%), Gaps = 17/121 (14%)

Query: 50  EDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQ 109
           E+E EG    EG  EEE +GEE  G+G E +     E +  E EG    +E+ EE    +
Sbjct: 828 EEEEEG----EGE-EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG----EEEGEE---GE 875

Query: 110 REAAERAMRQRDREAGRGLGRMRRGLLYDSDE-----EDEERPARKRRQVERATEDGEED 164
            E  E        E G G G    G     +E     E+EE   +   + E    +GEE+
Sbjct: 876 GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE 935

Query: 165 E 165
           E
Sbjct: 936 E 936



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 6/123 (4%)

Query: 50   EDESEGLLGTEGPLEEEE---DGEEL-IGDGMERDYRAIPELDAYEAEGLALDDEDVEEL 105
            E E EG    EG  EEEE   +GEE   G+G E +     E +  E EG   ++E   E 
Sbjct: 882  EGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941

Query: 106  TASQREAAERAMR-QRDREAGRGLGRMR-RGLLYDSDEEDEERPARKRRQVERATEDGEE 163
               + E  E     + + E G G G     G   + + E EE       + E   E+GEE
Sbjct: 942  EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001

Query: 164  DEE 166
            + E
Sbjct: 1002 EGE 1004



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 53/198 (26%), Positives = 75/198 (37%), Gaps = 34/198 (17%)

Query: 22  DPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDG-MERD 80
           D    S G++    +A     GR     E+ S G    +   EE E GE+  G G MER 
Sbjct: 632 DKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQD--EEREKGEKDKGRGEMERP 689

Query: 81  YRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAG----RGLGRMRRGLL 136
                EL    AE       D EE    +RE   +  R ++ E G     G G    G  
Sbjct: 690 GEGEKEL----AEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEG-- 743

Query: 137 YDSDEEDE------------------ERPARKRRQVERA--TEDGEEDEEMIESIENLED 176
            D +EE+E                  E+   +R++ ERA   E GEE+ +  E  E   +
Sbjct: 744 -DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETE 802

Query: 177 LKGHSVREWVSMAGPRLE 194
            +G    E   + G  +E
Sbjct: 803 GRGEEKEEGGEVEGGEVE 820



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 21/114 (18%)

Query: 51   DESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIP-ELDAYEAEGLALDDEDVEELTASQ 109
            +E EG    E   E EE+GE   G+G E +   +  E++  E EG   ++E  EE    +
Sbjct: 991  EEEEGEEEGEEEGEGEEEGE---GEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEERE 1047

Query: 110  REAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEE 163
            +E  E    +R+RE                +EE+EE   ++  + E   +DGEE
Sbjct: 1048 KE-GEGEENRRNRE----------------EEEEEEGKYQETGEEENERQDGEE 1084



 Score = 34.7 bits (78), Expect = 0.41
 Identities = 42/137 (30%), Positives = 55/137 (40%), Gaps = 19/137 (13%)

Query: 50   EDESEGLLGTEGPLEEEE---DGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELT 106
            E E EG  G EG  EEEE   +GEE  G+G E +     E +  E EG   + E   E  
Sbjct: 936  EGEGEGEDG-EGEGEEEEGEWEGEEEEGEG-EGEEEGEGEGEEGEGEGEEEEGEGEGEEE 993

Query: 107  ASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166
              + E  E        E G G G           EE+EE       + E    +GEE+E 
Sbjct: 994  EGEEEGEEEG---EGEEEGEGEG-----------EEEEEGEVEGEVEGEEGEGEGEEEEG 1039

Query: 167  MIESIENLEDLKGHSVR 183
              E  E  ++ +G   R
Sbjct: 1040 EEEGEEREKEGEGEENR 1056



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 29/120 (24%), Positives = 48/120 (40%), Gaps = 1/120 (0%)

Query: 66  EEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAG 125
           EE+G++  G+  E + R   + +  E EG  +++   E     +    E    + + E G
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEG 847

Query: 126 RGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGE-EDEEMIESIENLEDLKGHSVRE 184
            G      G   +  EE E     +  + E   E+GE E EE  E     E+ +G    E
Sbjct: 848 EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 41/128 (32%), Positives = 58/128 (45%), Gaps = 8/128 (6%)

Query: 50  EDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQ 109
           + E EG   T+G  EE ED  E  G G + +     E+ A + E    + E     T SQ
Sbjct: 778 QPEGEGETETQGKGEECEDENEAEGKG-DNEGEDEGEIHAEDGEMKGNEGE-----TESQ 831

Query: 110 REAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIE 169
             +AE     ++ E G   G    G   DS+EE+EE   ++  + E   E+ EE+EE  E
Sbjct: 832 ELSAENHGEAKNDEKGVEDGGGSDG--GDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEE 889

Query: 170 SIENLEDL 177
              N E L
Sbjct: 890 EKGNEEPL 897


>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 2 [Homo
            sapiens]
          Length = 1651

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 3/66 (4%)

Query: 98   DDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERA 157
            +D+DV+ +   QR  AER  R  +R   + L  MR+    D   ++EE   R+R++ ER 
Sbjct: 1584 EDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEE---RRRQEEERT 1640

Query: 158  TEDGEE 163
              D EE
Sbjct: 1641 KRDAEE 1646


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 44/181 (24%), Positives = 71/181 (39%), Gaps = 8/181 (4%)

Query: 13  SPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEEL 72
           SP +   G++P+ S+   S     +        L        G +  E  +EE+      
Sbjct: 135 SPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNL-----GQIAEETLVEEDLGQAAK 189

Query: 73  IGDGMERDYRAIPELDAYEA--EGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGR 130
            G G+    +   E  A E   +GL +  ED EE+     E ++    Q   +A      
Sbjct: 190 PGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESS 249

Query: 131 MRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAG 190
            ++G+L   +EEDEE    +  + E   E+ EE+EE  E  E  E+ +     E    A 
Sbjct: 250 KQKGIL-SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308

Query: 191 P 191
           P
Sbjct: 309 P 309



 Score = 37.0 bits (84), Expect = 0.083
 Identities = 32/141 (22%), Positives = 56/141 (39%), Gaps = 26/141 (18%)

Query: 58  GTEGPLEEEEDGEELIGDGMERDYRAIPEL-------DAYEAEGLALDDEDVEELTASQR 110
           G +G   + ED EE++    ER     P+        ++ + +G+   +E+ EE      
Sbjct: 210 GEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEE------ 263

Query: 111 EAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIES 170
           E  E    + D E              + +EE+EE    +  + E   E+ EE+EE    
Sbjct: 264 EEEEEEEEEEDEEE-------------EEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310

Query: 171 IENLEDLKGHSVREWVSMAGP 191
           +   ED    S ++   + GP
Sbjct: 311 VIFQEDTSHTSAQKAPELRGP 331


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 33/155 (21%)

Query: 56  LLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQRE---- 111
           +LG E  L+E      L+  G   + R   +L   EAE   L+    E L ASQ E    
Sbjct: 739 ILGLEQQLKETRG---LVDGGEAVEARLRDKLQRLEAEKQQLE----EALNASQEEEGSL 791

Query: 112 -AAERAMRQRDREAGRGLGRM----------------RRGLLYDSDEEDEERPARKRRQV 154
            AA+RA+  R  EA RGL R+                +R +L     E EE+     R V
Sbjct: 792 AAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTV 851

Query: 155 ERATED----GEEDEEMIESIE-NLEDLKGHSVRE 184
           +R  ++    GE+ ++ ++ ++  LED K  + RE
Sbjct: 852 DRLNKELEKIGEDSKQALQQLQAQLEDYKEKARRE 886



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 27/173 (15%)

Query: 56  LLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDE-----------DVEE 104
           LL T   LEE  +G++ + + +    R +  L     E +A  D+           D E+
Sbjct: 469 LLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQ 528

Query: 105 LTASQREAA-ERAMRQRDREAGRGLGRMRRGLLYDSDEE-----------DEERPARKRR 152
           L  S ++A  + A+ + +R+    L R  +  L ++ EE            E+  A K+ 
Sbjct: 529 LRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQE 588

Query: 153 QVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRT 205
            ++   E  E +EE+ E IE L+      + +  + AG   ++    K  LRT
Sbjct: 589 LLQLRMEKEEMEEELGEKIEVLQ----RELEQARASAGDTRQVEVLKKELLRT 637


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 44/169 (26%), Positives = 64/169 (37%), Gaps = 24/169 (14%)

Query: 11  ASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGR-DLPPFEDESEGLLGTEGPLEEEEDG 69
           AS P   +   + L ++PG            PG   LPP +   EG  G  GP   EED 
Sbjct: 819 ASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEED- 877

Query: 70  EELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLG 129
             +I      +     E +  E E    ++ED EE    + E  E               
Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEE-------------- 923

Query: 130 RMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLK 178
                   + +EE+E     +  + E   E+ EEDEE  E +E +EDL+
Sbjct: 924 --------EEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 40/121 (33%), Positives = 55/121 (45%), Gaps = 9/121 (7%)

Query: 59  TEGPLEEEEDG--EELIGDGMERDYRAIPELDAYEAEGLALDDEDVEE-LTASQREAAER 115
           T  P EEE D   E+   D  +       ELD +E   L  D+E  EE   A Q + AE+
Sbjct: 93  TSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHE---LDYDEEVPEEPAPAVQEDEAEK 149

Query: 116 AMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLE 175
           A  + D E G G  R        S  E E   A K ++ E   +DGE D+  I+  ++LE
Sbjct: 150 AGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKE--DDDGEIDDGEIDD-DDLE 206

Query: 176 D 176
           +
Sbjct: 207 E 207



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 11/113 (9%)

Query: 64  EEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQRE------AAERAM 117
           E+EE  + L  D + RD  +  +LD        L+DE+      SQ E        +RA 
Sbjct: 15  EDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHSDEEDRAS 74

Query: 118 RQRDREAGRGLGRMRRG-----LLYDSDEEDEERPARKRRQVERATEDGEEDE 165
             + ++    +  + RG        + DE +E+R +  R +    T + +E E
Sbjct: 75  EPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHE 127



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 38/141 (26%), Positives = 50/141 (35%), Gaps = 30/141 (21%)

Query: 50  EDESEGLLGTEGPLEEEEDG----EELIGDGMERDYRAI-------PELDAYEAEGLALD 98
           EDE        GP +EEED     E+   +   +D  +        P     E EG    
Sbjct: 49  EDEESA---ARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEG---- 101

Query: 99  DEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERAT 158
           DE  E+ T+  R+ A    R+ D                D DEE  E PA   ++ E   
Sbjct: 102 DEGEEDRTSDLRDEASSVTRELDEHE------------LDYDEEVPEEPAPAVQEDEAEK 149

Query: 159 EDGEEDEEMIESIENLEDLKG 179
              E+DEE  E     E   G
Sbjct: 150 AGAEDDEEKGEGTPREEGKAG 170



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 18/53 (33%), Positives = 26/53 (49%)

Query: 114 ERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166
           E   R+R+RE  R   R RR    + + E E    R+RR+ E   E  + DE+
Sbjct: 411 ENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEK 463


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 43/174 (24%), Positives = 75/174 (43%), Gaps = 19/174 (10%)

Query: 63   LEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDR 122
            L+EEE  EEL  +  E+  R   E    E E L    ++ E+L   +RE   R  R+R  
Sbjct: 906  LQEEE--EELQREEREKRRRQEQERQYREEEQL---QQEEEQLLREEREKRRRQERERQY 960

Query: 123  EAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHSV 182
               + L +    LL    EE E+R  ++R +  R  E+ +++EE +      E+ +    
Sbjct: 961  RKDKKLQQKEEQLL---GEEPEKRRRQEREKKYREEEELQQEEEQLLR----EEREKRRR 1013

Query: 183  REWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYED 236
            +EW      + E+    +  LR   +       K R+ +  ++ RE   +  E+
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREERE-------KRRLQERERQYREEEELQQEE 1060



 Score = 34.3 bits (77), Expect = 0.54
 Identities = 38/154 (24%), Positives = 60/154 (38%), Gaps = 21/154 (13%)

Query: 44   RDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDE--- 100
            R+    + E E LLG E      ++        +ER YR   EL   E + L  + E   
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQE--------LERQYRKEEELQQEEEQLLREEPEKRR 1102

Query: 101  ------DVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEED----EERPARK 150
                     E    Q+E  +    +R++   + L R  R       EE+    EE   R+
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162

Query: 151  RRQVERATEDGEEDEEMIESIENLEDLKGHSVRE 184
            R+++ER   + EE ++  E +   E  K    RE
Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERE 1196



 Score = 33.5 bits (75), Expect = 0.92
 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 12/109 (11%)

Query: 64  EEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDRE 123
           E+EE  ++L+    ER  + +        E   L  E+VE L   Q E  E+ +++ + E
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERL--EQEERREQRLKREEPE 626

Query: 124 AGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATED---GEEDEEMIE 169
                   RR  L  S+E++E R  + RR+ +   E     EE+EE +E
Sbjct: 627 ------EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 16/111 (14%)

Query: 66   EEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDV--EELTASQREAAERAMRQRDRE 123
            ++  E+L+G+  E+  R   E    E E L  ++E +  EE    +R+  ER  R++D  
Sbjct: 967  QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE- 1025

Query: 124  AGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENL 174
                            +EE   R  R++R+++       E+EE+ +  E L
Sbjct: 1026 -------------LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL 1063



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 17/168 (10%)

Query: 24  LTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGE--ELIGDGMERDY 81
           L   PG+  R+         R+L   E++SE     E    +  D E      +  ER+ 
Sbjct: 129 LEEEPGQRRRQK---RQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREE 185

Query: 82  RAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDE 141
           R   E      +G   ++   EE    +RE  E  +R++ RE  +   R R+  ++   +
Sbjct: 186 RRAEEEQLQSCKGHETEEFPDEE-QLRRRELLE--LRRKGREEKQQQRRERQDRVF---Q 239

Query: 142 EDEERPARKRRQVERATEDGEEDE------EMIESIENLEDLKGHSVR 183
           E+EE+  RKR  V R  E+  ++E      E+ E  E L  L+   +R
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR 287



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 15/92 (16%)

Query: 81  YRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSD 140
           Y A+ +    + E  A  D     L   ++E  +R    RDR+                +
Sbjct: 86  YYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQL---------------E 130

Query: 141 EEDEERPARKRRQVERATEDGEEDEEMIESIE 172
           EE  +R  +KR++ ER   +GEE  E  E +E
Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEKQERLE 162



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 17/59 (28%), Positives = 34/59 (57%)

Query: 109 QREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEM 167
           QR +A   +R++     R   R +R   +  +EE++E+  R+RR+ E+  +  EE+E++
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 2/84 (2%)

Query: 97  LDDEDVEELTASQREAAE-RAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVE 155
           L ++   +L A +R+  E R + + + +  R   R  R       EE+E+   R+R Q  
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQL 849

Query: 156 RATEDG-EEDEEMIESIENLEDLK 178
           +  EDG +ED+E   S E   D K
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQK 873


>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
          Length = 1113

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 9/116 (7%)

Query: 78  ERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLY 137
           E  + ++  L +    GL+ +   ++E    +RE      R+R+ +  R   R R     
Sbjct: 205 ELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKE 264

Query: 138 DSDEEDEERPARKRRQVERATEDGEEDEEMIES---------IENLEDLKGHSVRE 184
              E++ ER   + R++ER  E    ++E++ +         +  L  L+GH+  E
Sbjct: 265 REQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEE 320


>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
          Length = 1217

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 9/116 (7%)

Query: 78  ERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLY 137
           E  + ++  L +    GL+ +   ++E    +RE      R+R+ +  R   R R     
Sbjct: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKE 368

Query: 138 DSDEEDEERPARKRRQVERATEDGEEDEEMIES---------IENLEDLKGHSVRE 184
              E++ ER   + R++ER  E    ++E++ +         +  L  L+GH+  E
Sbjct: 369 REQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEE 424


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 38.5 bits (88), Expect = 0.029
 Identities = 39/184 (21%), Positives = 74/184 (40%), Gaps = 34/184 (18%)

Query: 14  PAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEE------- 66
           P ++  G   +   P R S R  A+      ++ P    S   + T+  + EE       
Sbjct: 2   PKRKAAGQGDMRQEPKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQ 61

Query: 67  ---EDGEELIGDGMERDYRA--------IPELDAYEAEGLALDDEDVEELT---ASQREA 112
              E  +E +   +E DY          I E  A E E + + +E++E+ T     ++EA
Sbjct: 62  AVAETKQEAV---VEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEA 118

Query: 113 AERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIE 172
               ++  + +              + D+ +E+  A K  + E+  EDG+ED+   E  E
Sbjct: 119 VAAEVKNEEEDQKED----------EEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGE 168

Query: 173 NLED 176
           + ++
Sbjct: 169 DAKE 172



 Score = 37.4 bits (85), Expect = 0.064
 Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 4/130 (3%)

Query: 50  EDESEGLLGTEGPLEE-EEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTAS 108
           ++E +G  G E   E+ EEDG+E   +G E+   A  + D  + E    + ED +E    
Sbjct: 137 QNEEKGEAGKEDKDEKGEEDGKE-DKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGED 195

Query: 109 QREAAERAMRQ--RDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEE 166
           ++E  +R      ++ E G+  G  + G      E+++ER   K  +     E G+E E+
Sbjct: 196 EKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKED 255

Query: 167 MIESIENLED 176
           + E  E  E+
Sbjct: 256 LKEEEEGKEE 265


>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 38.5 bits (88), Expect = 0.029
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 3/106 (2%)

Query: 63  LEEEEDGEELIGDGMERDYRAIPELDA---YEAEGLALDDEDVEELTASQREAAERAMRQ 119
           +E + + E+  G   ERD     E D     E E     D D +  T ++RE      +Q
Sbjct: 121 IERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180

Query: 120 RDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDE 165
           ++RE  R   R R        + D ER  +++ Q ER  E   E E
Sbjct: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE 226



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 18/77 (23%)

Query: 109 QREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMI 168
           +RE   R  RQRDR+ G+              E D ER  ++ R+ ER  E  +E +E  
Sbjct: 226 ERETDRRRERQRDRDRGK--------------ERDRERDRKEERKKERKKERKKERKEKK 271

Query: 169 ESIENLEDLKGHSVREW 185
           +  +  ED K    R+W
Sbjct: 272 KEEKRREDKK----RKW 284



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 13/125 (10%)

Query: 51  DESEGLLGTE------GPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDED--- 101
           D S G LG++      G  +  +D +   GD  +R+   + E    E +     D +   
Sbjct: 48  DFSRGRLGSQESPRSWGLGQAHKDAD---GDDRQRERDRVREKTEKERDRDRKRDRERRR 104

Query: 102 VEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDG 161
            E+ T   R+  ++   +RDRE  +  GR R        E D +R   + RQ E+   DG
Sbjct: 105 KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEK-DRDG 163

Query: 162 EEDEE 166
           + + E
Sbjct: 164 QRETE 168


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 38.5 bits (88), Expect = 0.029
 Identities = 45/182 (24%), Positives = 72/182 (39%), Gaps = 16/182 (8%)

Query: 20   GNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMER 79
            G +    S G  ++  +  T     D  P  D      G E P E EE+ +E  G+  E 
Sbjct: 2022 GVEAQPKSEGEEAQEVEGETQKTEGDAQPESD------GVEAP-EAEEEAQEAEGEVQEA 2074

Query: 80   DYRAIPE---LDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLL 136
            +  A PE   +DA EAEG A  + +  E   ++ EA +    +     G          +
Sbjct: 2075 EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEG--I 2132

Query: 137  YDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLE----DLKGHSVREWVSMAGPR 192
               + E E +P  +  + + A  + + + E IE+ E  E    +L+G    E    A P 
Sbjct: 2133 EAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPE 2192

Query: 193  LE 194
             E
Sbjct: 2193 SE 2194


>gi|149999615 variable charge, X-linked 3B [Homo sapiens]
          Length = 216

 Score = 38.5 bits (88), Expect = 0.029
 Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 10/152 (6%)

Query: 26  SSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIP 85
           ++PG S + +  L   P  +LPP E  SEG      PL +E + EE +    E +     
Sbjct: 72  AAPGPSDQPSQEL---PQHELPPEEPVSEGT--QHDPLSQESELEEPLSQESEVEEPLSQ 126

Query: 86  ELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEE 145
           E    E     L  E   E   SQ    E  + Q + E    L +  +     S E + E
Sbjct: 127 ESQVEEP----LSQESEVEEPLSQESQVEEPLSQ-ESEVEEPLSQESQVEEPLSQESEME 181

Query: 146 RPARKRRQVERATEDGEEDEEMIESIENLEDL 177
            P  +  QVE       E EE +     +E+L
Sbjct: 182 EPLSQESQVEEPLSQESEMEEPLSQESEMEEL 213


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 38.1 bits (87), Expect = 0.037
 Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 33/169 (19%)

Query: 12  SSPAQRRRGNDPLTSSPGRSSR-RTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGE 70
           S PA+     +    +P R+ R R D       R+L   E+E E         EEEED E
Sbjct: 243 SQPAEEEEDQE----TPSRNLRVRAD-------RNLKTEEEEEE-------EEEEEEDDE 284

Query: 71  ELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGR 130
           E  GD   +  R  P L  ++ EG        EE+    R   E  M +R +   +    
Sbjct: 285 EEEGDDEGQKSREAPILKEFKEEG--------EEIP---RVKPEEMMDERPKTRSQEQEV 333

Query: 131 MRRGLLYDSDEEDEERPARKRRQVE---RATEDGEEDEEMIESIENLED 176
           + RG  +   +E+  +    R+Q E   + T   EE+E  I+S + L++
Sbjct: 334 LERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKE 382



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 103 EELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRR-QVERATEDG 161
           EE   S  E   +  R+  R       ++  G     +EED+E P+R  R + +R  +  
Sbjct: 211 EEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTE 270

Query: 162 EEDEEMIESIENLEDLKG 179
           EE+EE  E  E+ E+ +G
Sbjct: 271 EEEEEEEEEEEDDEEEEG 288



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 32/124 (25%), Positives = 48/124 (38%), Gaps = 8/124 (6%)

Query: 65   EEEDGEELIGDGMERDYRA-----IPELDAYEAEGLALDDEDVEELTASQREAAERAMRQ 119
            +EE   +L+ D   +   A     +P  D+   +  A   E  +E    ++E  E   ++
Sbjct: 1203 QEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKE 1262

Query: 120  RDREAGRGLGRM--RRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDL 177
            R++EA R   R   R      S E D ER   + R       D E D E      +  D 
Sbjct: 1263 REKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRE-RDRRDT 1321

Query: 178  KGHS 181
            K HS
Sbjct: 1322 KRHS 1325


>gi|17136078 VGF nerve growth factor inducible precursor [Homo
           sapiens]
          Length = 615

 Score = 38.1 bits (87), Expect = 0.037
 Identities = 40/138 (28%), Positives = 57/138 (41%), Gaps = 30/138 (21%)

Query: 43  GRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDV 102
           GR L    +E E     E   +E   GEE +G+  E +  A  E +A EAE         
Sbjct: 348 GRGLQEAAEERESAREEEEAEQERRGGEERVGE--EDEEAAEAEAEAEEAE--------- 396

Query: 103 EELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGE 162
                  R+ A     + D EAG            +     EE P  +R++ E   E GE
Sbjct: 397 -----RARQNALLFAEEEDGEAGA-----------EDKRSQEETPGHRRKEAEGTEEGGE 440

Query: 163 E--DEEM-IESIENLEDL 177
           E  DEEM  ++I++L +L
Sbjct: 441 EEDDEEMDPQTIDSLIEL 458


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 38.1 bits (87), Expect = 0.037
 Identities = 46/165 (27%), Positives = 61/165 (36%), Gaps = 14/165 (8%)

Query: 12  SSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEE 71
           SSP + +  ND L     R  RR D +           + E E     E   E E D E 
Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER 701

Query: 72  LIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRM 131
                +ER+ RA       E E     D D +     +RE      R+RDRE  R   R 
Sbjct: 702 EKERELERE-RAREREREREKERDRERDRDRDHDRERERE------RERDREKERERERE 754

Query: 132 RRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLED 176
            R       E + ER   + R+ ER  E   E ++  E   + ED
Sbjct: 755 ER-------ERERERERERERERERERERARERDKERERQRDWED 792


>gi|6005757 chromatin-specific transcription elongation factor large
            subunit [Homo sapiens]
          Length = 1047

 Score = 37.7 bits (86), Expect = 0.049
 Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 12/120 (10%)

Query: 43   GRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDE-- 100
            G D    + ESE    T  P E++ + EE   +  + DY +  E   Y  E L  ++E  
Sbjct: 931  GSDAEEGDSESEIEDETFNPSEDDYEEEE---EDSDEDYSSEAEESDYSKESLGSEEESG 987

Query: 101  -DVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDS------DEEDEERPARKRRQ 153
             D +EL    R+A   +  + + E  R + R R+  ++ S             P +K+R+
Sbjct: 988  KDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK 1047


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,781,411
Number of Sequences: 37866
Number of extensions: 1594834
Number of successful extensions: 8926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 222
Number of HSP's that attempted gapping in prelim test: 7684
Number of HSP's gapped (non-prelim): 1049
length of query: 904
length of database: 18,247,518
effective HSP length: 111
effective length of query: 793
effective length of database: 14,044,392
effective search space: 11137202856
effective search space used: 11137202856
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press