Search of human proteins with 33354279

Search of human proteins with 33354279

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33354279 hypothetical protein LOC55425 [Homo sapiens]
         (340 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33354279 hypothetical protein LOC55425 [Homo sapiens]              692   0.0  
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    50   3e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    50   4e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    49   6e-06
gi|217330641 IWS1 homolog [Homo sapiens]                               48   1e-05
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    47   2e-05
gi|104526627 triadin [Homo sapiens]                                    46   5e-05
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          45   7e-05
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  44   3e-04
gi|16445033 ACRC protein [Homo sapiens]                                44   3e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             43   4e-04
gi|164419758 bromodomain containing 2 [Homo sapiens]                   43   5e-04
gi|4826806 bromodomain containing 2 [Homo sapiens]                     43   5e-04
gi|55956788 nucleolin [Homo sapiens]                                   42   6e-04
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform...    42   6e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         42   6e-04
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    42   6e-04
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    42   6e-04
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    42   6e-04
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    42   8e-04
gi|7661950 SH2 domain binding protein 1 [Homo sapiens]                 42   8e-04
gi|59814411 hypothetical protein LOC253725 [Homo sapiens]              42   8e-04
gi|16904383 leucine rich repeat containing 7 [Homo sapiens]            42   0.001
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    41   0.001
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                41   0.001
gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo ...    41   0.001
gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo ...    41   0.001
gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo ...    41   0.001
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    41   0.001
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    41   0.001

>gi|33354279 hypothetical protein LOC55425 [Homo sapiens]
          Length = 340

 Score =  692 bits (1786), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 1   MARDLIGPALPPGFKARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEG 60
           MARDLIGPALPPGFKARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEG
Sbjct: 1   MARDLIGPALPPGFKARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEG 60

Query: 61  NQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFI 120
           NQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFI
Sbjct: 61  NQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFI 120

Query: 121 KSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDD 180
           KSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDD
Sbjct: 121 KSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDD 180

Query: 181 DSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEA 240
           DSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEA
Sbjct: 181 DSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEA 240

Query: 241 RKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIP 300
           RKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIP
Sbjct: 241 RKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIP 300

Query: 301 FDRDKDLKVNRFDEAQKKALIKKSRELNTRFSHGKGNMFL 340
           FDRDKDLKVNRFDEAQKKALIKKSRELNTRFSHGKGNMFL
Sbjct: 301 FDRDKDLKVNRFDEAQKKALIKKSRELNTRFSHGKGNMFL 340


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 62/303 (20%), Positives = 111/303 (36%), Gaps = 29/303 (9%)

Query: 11  PPGFKARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSG 70
           PP  KA   A+     P   A  A   +    SSD  D ++      ++G +   +    
Sbjct: 100 PPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKA 159

Query: 71  PTARKQRKNQDDDDDDDD----GFFGPALPPGFKKQDDSPPRPI-IGPALPPG--FIKST 123
           P  + +  + D D   +D           P   K Q  +PP+P    P +  G     S+
Sbjct: 160 PPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSS 219

Query: 124 QKSDKGRDDPGQQETDSSEDEDII--GPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDD 181
             S     D  ++E  ++  +  +    + AK PV     T   +++   ++  +  +++
Sbjct: 220 SSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPV--KAATTPTRKSSSSEDSSSDEEEE 277

Query: 182 SSKPIVRESW------MTELPPEMKDFGLGP---RTFKRRADDTSGDRSIWTDTPADRER 232
             KP+  +            PP  K  G  P      K++  ++S D S  +D+ ++ E+
Sbjct: 278 QKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEK 337

Query: 233 KAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDK 292
           K        K+++K           K+ AE  S  ++S  SE   D    K         
Sbjct: 338 KPPTKAVVSKATTKPPPA-------KKAAESSSDSSDSDSSED--DEAPSKPAGTTKNSS 388

Query: 293 NKP 295
           NKP
Sbjct: 389 NKP 391



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 62/313 (19%), Positives = 110/313 (35%), Gaps = 44/313 (14%)

Query: 8   PALPPGFKARGTAEDEERDPSPVAGPALPPNYK--------SSSSDSSDSDEDSSSLYEE 59
           P+ P G     + +      SP   PA  P           +  +DSS S+E+SSS  EE
Sbjct: 377 PSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEE 436

Query: 60  GNQE----------SEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRP 109
             ++          ++   S P  +  + ++D   D D            K      P+ 
Sbjct: 437 KTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQK 496

Query: 110 IIGPALP--PGFI---KSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEF 164
           + G A P  P      K+   +    DD  ++E +  + +    P   K      +T + 
Sbjct: 497 VAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQN 556

Query: 165 EKRAQRMKEK----------LTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRAD 214
            K A+  +E+          ++K      +     +   E P   K     P TF +R  
Sbjct: 557 GKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKR-- 614

Query: 215 DTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSE 274
              G++     +P  R R+ +   ++R + +  D +   +G     A QV  + + K   
Sbjct: 615 -KKGEKR--ASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLKFTKGK--- 668

Query: 275 SLMDIHHKKLKSK 287
                 H+K K K
Sbjct: 669 ---SFRHEKTKKK 678



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 60/268 (22%), Positives = 99/268 (36%), Gaps = 35/268 (13%)

Query: 69  SGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDK 128
           +GP A+K +K     D +D       +     K+   P + +    LPPG  K+  K+ +
Sbjct: 71  NGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRV---GLPPG--KAAAKASE 125

Query: 129 GRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFE-KRAQRMKEKLTKGDDDSS---- 183
                   + D  ED+        K PV   V  + +  +A   K K +  D DSS    
Sbjct: 126 SSSSEESSDDDDEEDQ-------KKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDE 178

Query: 184 -----KP---IVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAK 235
                KP    V     T+ PP  K     P+    +A  +S   S  + +    E KA 
Sbjct: 179 PPKNQKPKITPVTVKAQTKAPP--KPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAA 236

Query: 236 ETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKP 295
            T   +K+  KK        +      + SS +E   S+       ++ + K  ++K  P
Sbjct: 237 AT--PKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSD------EEEEQKKPMKNKPGP 288

Query: 296 QERIPFDRDKDLKVNRFDEAQKKALIKK 323
              +P       K +   +  KKA+ K+
Sbjct: 289 YSSVPPPSAPPPKKSLGTQPPKKAVEKQ 316


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 47/231 (20%), Positives = 93/231 (40%), Gaps = 39/231 (16%)

Query: 40   KSSSSDSSDSDEDSSSLYEEGNQESE------EDDSGPTARKQRKNQDDDDDD----DDG 89
            +    D  + +ED    +EE  +E E      E++ G    ++ +  ++++++    +D 
Sbjct: 904  EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL 963

Query: 90   FFGPALPPGFKKQDDSPPRPIIGPALP----PGFIKSTQKSDKGR----DDPGQQETDSS 141
             FG A   G + ++ +PP P + PALP    P  ++   + + G     ++PG +E   +
Sbjct: 964  EFGTA---GGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGA 1020

Query: 142  EDEDIIGP--------------MPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIV 187
            +    + P               PA GP    +  E       + E+ T+   D  +P  
Sbjct: 1021 DTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080

Query: 188  RESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQ 238
                  E+  E +   L     ++  DDT+   + + D P D E+    T+
Sbjct: 1081 ETPAEEEMETETEAEALQ----EKEQDDTAAMLADFIDCPPDDEKPPPPTE 1127



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 33/166 (19%)

Query: 14   FKARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSL--YEEGNQESEEDDSGP 71
            F   G   +E   P P   PALPP             E    L   E G +E    D+ P
Sbjct: 965  FGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAP 1024

Query: 72   T-ARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPII--GPALPPGFIKSTQKSDK 128
            T A +   +Q + + + +    PA  P        PP+ ++   P+ PP  +        
Sbjct: 1025 TLAPEALPSQGEVEREGE---SPAAGP--------PPQELVEEEPSAPPTLL-------- 1065

Query: 129  GRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEK 174
                  ++ET+   D+  + P P + P    + TE E  A + KE+
Sbjct: 1066 ------EEETEDGSDK--VQP-PPETPAEEEMETETEAEALQEKEQ 1102


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 70/322 (21%), Positives = 117/322 (36%), Gaps = 56/322 (17%)

Query: 21  EDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQ 80
           +D  + P    G A   N K    D S+ DED+S   +E ++ +   +SG          
Sbjct: 141 DDFNKLPKKAKGKAQKSNKKW---DGSEEDEDNSKKIKERSRINSSGESG---------- 187

Query: 81  DDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDS 140
               D+ D F       G KK   + P P I                    + G ++ D+
Sbjct: 188 ----DESDEFLQSR--KGQKKNQKNKPGPNI--------------------ESGNEDDDA 221

Query: 141 SEDEDIIGPMPAKGPVNYNVTTEFEK---RAQRMKEKLTKGDDDSSKPIVRESWMTELPP 197
           S     +    A+         + EK   R  + KE+L  G  D SK    +    E   
Sbjct: 222 SFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV 281

Query: 198 EMK---DFGLGPRTFKR------RADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKD 248
           + K   D G+ P + ++        DD  GD+        D+++K  E +E  K   K  
Sbjct: 282 KSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK-----KKDKKKKKGEKEEKEKEKKKGP 336

Query: 249 EEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDLK 308
            +  +    + LA+        KR E       ++L++K  E++   QE+    + K+ +
Sbjct: 337 SKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKE 396

Query: 309 VNRFDEAQKKALIKKSRELNTR 330
                + + K L K  RE   R
Sbjct: 397 RKERLKKEGKLLTKSQREARAR 418



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 73/315 (23%), Positives = 124/315 (39%), Gaps = 52/315 (16%)

Query: 40  KSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGF 99
           K  S D +DS+E           E ++  S  TA+ + +     DDDDD    P    G 
Sbjct: 104 KKQSFDDNDSEE----------LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGK 153

Query: 100 -----KKQDDSPP----------RPIIGPALPPG-----FIKSTQKSDKG-RDDPGQQET 138
                KK D S            R  I  +   G     F++S +   K  ++ PG    
Sbjct: 154 AQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIE 213

Query: 139 DSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPE 198
             +ED+D           ++ + T  +K+A++ + +  K D++ +K + +     EL   
Sbjct: 214 SGNEDDD----------ASFKIKTVAQKKAEKKERERKKRDEEKAK-LRKLKEKEELETG 262

Query: 199 MKDFGLGPRTFKRRADDTSGDRSIWTDT---PADRERKAKETQ-EARKSSSKKDEEHILS 254
            KD      + +R+ ++ +    +  DT   PA  E+    T  E      KK ++    
Sbjct: 263 KKDQSKQKES-QRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKK 321

Query: 255 GRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDLKVNRFDE 314
             +K   E+      SK +   M     KLK +    K + +ERI   R ++L+  R +E
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERI--KRLEELEAKRKEE 379

Query: 315 ---AQKKALIKKSRE 326
               Q+K   KK +E
Sbjct: 380 ERLEQEKRERKKQKE 394



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 67/304 (22%), Positives = 120/304 (39%), Gaps = 48/304 (15%)

Query: 40  KSSSSDSSDSDEDSSSLYEE-----GNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPA 94
           K+ S DS+  D D  +L  E       +E E   S    +K++K QD D+DD        
Sbjct: 6   KNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDI------- 58

Query: 95  LPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKG 154
                K+ ++         +L    IK+ +++   +     +E  +S+D+   G    K 
Sbjct: 59  ----LKELEEL--------SLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQ 106

Query: 155 PVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRAD 214
             + N + E E +  + K+        ++KP V    M     +  DF   P+  K +A 
Sbjct: 107 SFDDNDSEELEDKDSKSKK--------TAKPKVE---MYSGSDDDDDFNKLPKKAKGKA- 154

Query: 215 DTSGDRSIWTDTPADRERKAKETQEARKSSSKKDE-EHILSGRDKRLAEQ-------VSS 266
             S  +   ++   D  +K KE      S    DE +  L  R  +   Q       + S
Sbjct: 155 QKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIES 214

Query: 267 YNE-SKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDK---DLKVNRFDEAQKKALIK 322
            NE    S  +  +  KK + K  E K + +E+    + K   +L+  + D++++K   +
Sbjct: 215 GNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQR 274

Query: 323 KSRE 326
           K  E
Sbjct: 275 KFEE 278


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 57/299 (19%), Positives = 111/299 (37%), Gaps = 32/299 (10%)

Query: 38  NYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPP 97
           N +  +  +SDS+ +    +   + E EE    P +  + ++       D     P    
Sbjct: 135 NEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQ 194

Query: 98  GFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVN 157
               +++ PP+P +  +      K  Q SD   ++P + +   SE+E++  P        
Sbjct: 195 ASDSENEEPPKPRMSDSESEELPK-PQVSDSESEEPPRHQASDSENEELPKPR------- 246

Query: 158 YNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTS 217
               ++ E       +     +++  KP + +S   + P             K R  D+ 
Sbjct: 247 ---ISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSE 303

Query: 218 GDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLM 277
                 ++ P        ET++A +   K + +      +K   E     N+S  S+S M
Sbjct: 304 ------SEGPQKGPASDSETEDASRHKQKPESDDDSDRENK--GEDTEMQNDSFHSDSHM 355

Query: 278 DIHHKKLKSKAAEDKNKPQERIPFDRD-----------KDLKVNRFDEAQKKALIKKSR 325
           D   KK  S  +E++   ++++  D D           +   V    E ++KA  KKSR
Sbjct: 356 D--RKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSR 412



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 70/345 (20%), Positives = 133/345 (38%), Gaps = 73/345 (21%)

Query: 20  AEDEERDPSPVAGPALPPNYKSSSSDS----------SDSDEDSSSLYEEGNQESEEDD- 68
           +E+E+    P +   +    KS +SDS          SDS+ +    ++  + E+EE   
Sbjct: 146 SENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPK 205

Query: 69  ---SGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPAL---PPGFIKS 122
              S   + +  K Q  D + ++    P        +++  P+P I  +    PP    S
Sbjct: 206 PRMSDSESEELPKPQVSDSESEE----PPRHQASDSENEELPKPRISDSESEDPPRHQAS 261

Query: 123 TQK---------SDKGRDDPGQQETDSSEDEDIIGPM--------PAKGPVNYNVTTEFE 165
             +         SD   +DP + +   SE+E++  P         P KGP + + T +  
Sbjct: 262 DSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETED-- 319

Query: 166 KRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDR-SIWT 224
             A R K+K  + DDDS +                         + + +DT     S  +
Sbjct: 320 --ASRHKQK-PESDDDSDR-------------------------ENKGEDTEMQNDSFHS 351

Query: 225 DTPADRER---KAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHH 281
           D+  DR++      E +E +K     DE+    G ++++A++ ++       E       
Sbjct: 352 DSHMDRKKFHSSDSEEEEHKKQKMDSDEDE-KEGEEEKVAKRKAAVLSDSEDEEKASAKK 410

Query: 282 KKLKSKAAEDKNKPQERIPFDRDKDLKVNRFDEAQKKALIKKSRE 326
            ++ S A +  +         R+K +  +  +EA K+   KK+ E
Sbjct: 411 SRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEE 455


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 82/339 (24%), Positives = 133/339 (39%), Gaps = 64/339 (18%)

Query: 7    GPALPPGFKARGTAEDEERDPSPVAGP-------ALPPNYKSSSSDSSDSDEDSSSLYEE 59
            G  L P  +     E E++D     GP         P  YK  SSD    D+   S+ E+
Sbjct: 994  GKGLEPWERHHPAREKEKKD-----GPDKERKEKTKPERYKEKSSDK---DKSEKSILEK 1045

Query: 60   GNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGF 119
              Q+ +E D     +K  K +  D    D     +L  G +K++ + P  I         
Sbjct: 1046 C-QKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGII--------- 1095

Query: 120  IKSTQKSDKGRDDPGQQE--------TDSSEDE--DIIGPMPAKGPVNYNVTTEFEKRAQ 169
              S   S+K  D  G+++        TD SED+    +G     G  +    T+      
Sbjct: 1096 --SEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTD------ 1147

Query: 170  RMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPAD 229
             ++EK  +G +  +    R+S   + P   KD     R   R A D   D+    +   +
Sbjct: 1148 GLQEK-EEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKK---EKVFE 1203

Query: 230  RERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAA 289
            + ++ K+ +   K   +KD   + S +DK+        N+ K  E       K  K  AA
Sbjct: 1204 KHKEKKDKESTEKYKDRKDRASVDSTQDKK--------NKQKLPE-------KAEKKHAA 1248

Query: 290  EDKNKPQERIPFDRD--KDLKVNRFDEAQKKALIKKSRE 326
            EDK K + +   D++  K+ K +R  +A+K  L K   E
Sbjct: 1249 EDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEE 1287



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 38/161 (23%), Positives = 73/161 (45%), Gaps = 11/161 (6%)

Query: 172 KEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRE 231
           K K+ K D D  K   +E  ++++  E K++        +R  DT+ D S       DR 
Sbjct: 683 KLKVLKHDRDHFK---KEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRS 739

Query: 232 RKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAED 291
            KA++ +  ++ S K+++  +     K+ ++   S  E K+++   D   K+ +    ED
Sbjct: 740 NKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLE-KKNDLKEDKISKEKEKIFKED 798

Query: 292 KNKPQERIPFDRDKDLKVNRFDEAQKKALIKKSRELNTRFS 332
           K K ++   +  D     + FDE   K    ++ +  T+FS
Sbjct: 799 KEKLKKEKVYRED-----SAFDEYCNKNQFLENED--TKFS 832



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 56/256 (21%), Positives = 93/256 (36%), Gaps = 48/256 (18%)

Query: 40   KSSSSDSSDSDEDSSSLYEEGNQESE--------EDDSGPTARKQRKNQ---------DD 82
            K    D+   D++  +  ++G ++ E        ED S     K+ K +         D+
Sbjct: 1063 KEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDE 1122

Query: 83   DDDDDDGFFGPALPPGFKKQDDSP-PRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSS 141
             +DD D   G     GFK  + S  PR         G  +    SD+ R    +Q  +  
Sbjct: 1123 SEDDRDSCMGS----GFKMGEASDLPRTDGLQEKEEG--REAYASDRHRKSSDKQHPERQ 1176

Query: 142  EDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKD 201
            +D++       +G  +     + EK  ++ KEK  K   +  K             + KD
Sbjct: 1177 KDKEPRDRRKDRGAADAGRDKK-EKVFEKHKEKKDKESTEKYK-------------DRKD 1222

Query: 202  FGLGPRTFKRRADDTSGDRSIWTDTPADRERK-AKETQEARKSSSKKDEEHILSGRDKRL 260
                     R + D++ D+      P   E+K A E +   K   K D+EH    +  R 
Sbjct: 1223 ---------RASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRS 1273

Query: 261  AEQVSSYNESKRSESL 276
            A+   S  E    E+L
Sbjct: 1274 ADAEKSLLEKLEEEAL 1289


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 42/178 (23%), Positives = 84/178 (47%), Gaps = 22/178 (12%)

Query: 126 SDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKP 185
           S+   DD G ++TD  E ++   P   K  ++ + T + EK  ++++ K+T  + +  K 
Sbjct: 116 SEDEEDDDGDEDTDKGEIDE---PPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKE 172

Query: 186 IVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSS 245
            VRE    +  PE K       T K + +         T T A  ++KAK  ++    S 
Sbjct: 173 KVRE----KEKPEKK------ATHKEKIEKKEKPE---TKTLAKEQKKAKTAEK----SE 215

Query: 246 KKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDR 303
           +K ++ +  G+ +++ +  +   E +++ S      K+ K KAA  K++ +++  F R
Sbjct: 216 EKTKKEVKGGKQEKVKQTAAKVKEVQKTPS--KPKEKEDKEKAAVSKHEQKDQYAFCR 271



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 56/276 (20%), Positives = 106/276 (38%), Gaps = 40/276 (14%)

Query: 93  PALPPGFKKQDDSPPRPIIGPALPP-------GFIKSTQKSDKGRDDPGQQETDSSEDED 145
           PA+PP    +  S P P   PAL            K T ++ K   +  +++++     D
Sbjct: 288 PAIPPPLPTEQASRPTPA-SPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAID 346

Query: 146 IIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLG 205
           +    P K       T +   +A   K++  +    + KP   E    +   E K+  + 
Sbjct: 347 VEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGK-KQEKKEKHVE 405

Query: 206 PRTFKRRADDTSGDRSIWTDT----------------PADRERKAKET--QEARK----- 242
           P    ++      D+ +   T                P  +E K  +T  QE RK     
Sbjct: 406 PAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGK 465

Query: 243 -SSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPF 301
            SS  KD+E I  G+++++   +       + +  M    K++K K  + + K +E+   
Sbjct: 466 TSSILKDKEPI-KGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEP 524

Query: 302 DRDKDLK--VNRFDEAQKKALIKKSRELNTRFSHGK 335
              K+ K  ++   +  K+ ++K  + +    SHGK
Sbjct: 525 QIKKEAKPAISEKVQIHKQDIVKPEKTV----SHGK 556


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 13/91 (14%)

Query: 12  PGFKARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSD---------EDSSSLYEEGNQ 62
           P  K R T + + ++P+P   P       SS  +  DSD         ED    Y E N 
Sbjct: 56  PLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDND 115

Query: 63  E----SEEDDSGPTARKQRKNQDDDDDDDDG 89
           E     EED+ G    ++   ++D+DDD+DG
Sbjct: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 57/320 (17%), Positives = 120/320 (37%), Gaps = 21/320 (6%)

Query: 15  KARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTAR 74
           K++   E+++R  S  +  +   +  SSS   S SD   S    E   +  +      +R
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239

Query: 75  KQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPG 134
           K +K +             +     + Q  S  RP   P +P    +   +    + D  
Sbjct: 240 KHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPEN--RFLMRKSPPKADEK 297

Query: 135 QQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESW-MT 193
           +++    E E    P P   P +Y       +  +++K +  +     S+   R+ +  +
Sbjct: 298 ERKNRERERERECNP-PNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRS 356

Query: 194 ELPPEMKD---------FGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSS 244
           E PP  +             G R  K    + +  +         +ERK  + +   +S 
Sbjct: 357 ETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESP 416

Query: 245 SKKDEEHILSGRDKRLAEQVSSYNES--KRSESLMDIHHKKLKSKAAEDKNKPQERIPFD 302
           ++K+E      ++K++ +  S+  E   +R+    D +  K+K +A        +     
Sbjct: 417 NRKNE------KEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKS 470

Query: 303 RDKDLKVNRFDEAQKKALIK 322
           +++D K NR +E + ++  K
Sbjct: 471 KERDSKHNRNEEKRMRSRSK 490



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 10/132 (7%)

Query: 209 FKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYN 268
           ++RR    S +R     TP  R R     +  R S S + EE     +DK   ++  S +
Sbjct: 598 YRRRGRSRSRERR----TPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSH 653

Query: 269 ESKRSESLMDIHHKKL---KSKAAEDKNKPQERIPFDRDKDLKVNRFDEAQKKALIKKSR 325
             + SES   ++ K      S  + +K   +++ PF +   +K +  D   K +++K   
Sbjct: 654 RKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSK---IKQSSQDNELKSSMLKNKE 710

Query: 326 ELNTRFSHGKGN 337
           +   R S  K N
Sbjct: 711 DEKIRSSVEKEN 722



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 22/133 (16%)

Query: 210 KRRADDTSGDRSIWTDTPADR---------ERKAKETQEARKSSSKKDEEHILSGRDKRL 260
           +RR D  S +R        D+          RK     E R  S  +D     + R+K+ 
Sbjct: 623 RRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKA 682

Query: 261 AEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDLKVNRFDEAQKKAL 320
               S +++ K+S         +LKS     KNK  E+I   R    K N+  + Q+   
Sbjct: 683 DRDQSPFSKIKQSS-----QDNELKSSML--KNKEDEKI---RSSVEKENQKSKGQENDH 732

Query: 321 IKKSRELNTRFSH 333
           +    E N +F H
Sbjct: 733 V---HEKNKKFDH 742


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 63/319 (19%), Positives = 107/319 (33%), Gaps = 50/319 (15%)

Query: 20  AEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESE-EDDSGPTARKQRK 78
           A D+  D S V       +   +S DSSD + D S + ++ + +S+  DDS   +     
Sbjct: 178 APDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDD 237

Query: 79  NQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQET 138
           + DD +  DD       P       ++P         P      ++ SD   DD  +   
Sbjct: 238 SSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDD-SEASD 296

Query: 139 DSSED----------------------------EDIIGPMPAKGPVNYNVTTEFEKRAQR 170
           DSS+D                            +D+  P+PA+   N       E+    
Sbjct: 297 DSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVE 356

Query: 171 MKEKLTK-------GDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIW 223
               +++       G+ D  + + +     E  PE+ +  L          + SG R   
Sbjct: 357 AAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSK 416

Query: 224 TDT----PADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDI 279
           T T    P  R+ K K   E  +    K          K + E +       ++ S+   
Sbjct: 417 TKTIVEPPRKRQTKTKNIVEPPRKRQTK---------TKNIVEPLRKRKAKTKNVSVTPG 467

Query: 280 HHKKLKSKAAEDKNKPQER 298
           H K+  SK      K ++R
Sbjct: 468 HKKRGPSKKKPGAAKVEKR 486



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 55/249 (22%), Positives = 92/249 (36%), Gaps = 35/249 (14%)

Query: 22  DEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQD 81
           D+   P   +  +  P+  S  S++ D + D S + ++ + +S +D+S  ++     N D
Sbjct: 154 DDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSS---DDNSD 210

Query: 82  DDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSS 141
           D D  DD      +P       D P         P      ++  D   DD  +   DSS
Sbjct: 211 DSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDD-SEAPDDSS 269

Query: 142 EDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKD 201
           +D        ++ P + +  +E    +    E      DDS  P   +S  +++P +  D
Sbjct: 270 DD--------SEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAP-DDKSDDSDVPEDKSD 320

Query: 202 FGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRDKRLA 261
               P       DD S D     + P   E    E Q A       DEE ++       A
Sbjct: 321 DSDVP-------DDNSDD----LEVPVPAEDLCNEGQIA------SDEEELVEA-----A 358

Query: 262 EQVSSYNES 270
             VS ++ S
Sbjct: 359 AAVSQHDSS 367



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 48/217 (22%), Positives = 75/217 (34%), Gaps = 42/217 (19%)

Query: 37  PNYKSSSSDSSDSDEDSSSLYEEGNQESEE-DDSGPTARKQRKNQDDDDDDDDGFFGPAL 95
           P+  S  S++ D + D S   ++ + +SE  DD+   +     N DD D  DD       
Sbjct: 139 PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDD------- 191

Query: 96  PPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGP 155
                  DDS                S   SD   DD    + D S+D D+        P
Sbjct: 192 -----NSDDSSDD------------NSDDSSDDNSDDSDVPD-DKSDDSDV--------P 225

Query: 156 VNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADD 215
            + +  ++    +    E      DDS  P    S  +E P +  D    P       DD
Sbjct: 226 DDSSDDSDVPDDSSDDSEAPDDSSDDSEAP-DDSSDDSEAPDDSSDDSEAP-------DD 277

Query: 216 TSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHI 252
           +S D     D+  D E     + ++     K D+  +
Sbjct: 278 SSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDV 314



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 55/319 (17%), Positives = 105/319 (32%), Gaps = 35/319 (10%)

Query: 15  KARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTAR 74
           +A   + D+   P   +  +  P+  S  S++ D   D S   ++ + +SE  D      
Sbjct: 243 EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDS 302

Query: 75  KQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPG 134
           +   ++ DD D  +     +  P     D   P P              ++  +      
Sbjct: 303 EAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVS 362

Query: 135 QQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTE 194
           Q ++     E  +G   +K P +     E  +R    +E+     + S K   +   + E
Sbjct: 363 QHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVE 422

Query: 195 LPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQE-ARKSSSKKDEEHIL 253
            P             ++R   T        + P  R+ K K   E  RK  +K     + 
Sbjct: 423 PP-------------RKRQTKTKN----IVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVT 465

Query: 254 SGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAE---------DKNKPQERIPFDRD 304
            G  KR          SK+      +  +K ++   +         +K+K        R+
Sbjct: 466 PGHKKR--------GPSKKKPGAAKVEKRKTRTPKCKVPGCFLQDLEKSKKYSGKNLKRN 517

Query: 305 KDLKVNRFDEAQKKALIKK 323
           KD  V R  +   +++  K
Sbjct: 518 KDELVQRIYDLFNRSVCDK 536


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 60/314 (19%), Positives = 121/314 (38%), Gaps = 57/314 (18%)

Query: 31  AGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDDGF 90
           AG  +  +Y +   + SD DE  S+  +E N E    D G  A +  +N+ + D+  +  
Sbjct: 320 AGAQMEVDY-TEQLNFSDDDEQGSNSPKENNSE----DQGSKASENNENKKETDEVSNTK 374

Query: 91  FGPALP-------------PGFKKQDDS-----PPRPIIGPALPPGFIKSTQKSDKGRDD 132
               +P             P F ++  +     PP  ++    PP      +++  GR  
Sbjct: 375 SSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPP----PDRQAVPGRPG 430

Query: 133 PGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWM 192
           P   +   + DED I     +     +   E   RA++ +E+  +  ++  K    E   
Sbjct: 431 PFPSKQQVA-DEDEIWKQRRRQQSEISAAVE---RARKRREEEERRMEEQRKAACAEKL- 485

Query: 193 TELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHI 252
                             +R D+  G           RER+ ++ +E  K   K+ E+  
Sbjct: 486 ------------------KRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQER 527

Query: 253 LSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDLKVNRF 312
              R+K    Q     E ++ +       ++++ +  ++K K  ER    ++K+ ++ + 
Sbjct: 528 EKEREKDRERQQEKEKELEKEQE----KQREMEKERKQEKEKELER---QKEKEKELQKM 580

Query: 313 DEAQKKALIKKSRE 326
            E +K+  ++K RE
Sbjct: 581 KEQEKECELEKERE 594



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 47/257 (18%), Positives = 94/257 (36%), Gaps = 25/257 (9%)

Query: 83  DDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETD--- 139
           D + D+G+ G  +   + +Q +       G   P       Q S    ++  ++ETD   
Sbjct: 312 DAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVS 371

Query: 140 SSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEM 199
           +++    I   P+   V Y     F +          +G      P  +       PP+ 
Sbjct: 372 NTKSSSQIPAQPSVAKVPYGKGPSFNQE---------RGTSSHLPPPPKLLAQQHPPPDR 422

Query: 200 KDFGLGPRTFKRRADDTSGDRSIWTD---------TPADRERKAKETQEARKSSSKKDEE 250
           +     P  F  +      D  IW              +R RK +E +E R    +K   
Sbjct: 423 QAVPGRPGPFPSKQQVADEDE-IWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAA- 480

Query: 251 HILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDLKVN 310
              + + KRL E++    +    E + +   +K + +  E + + ++    +R+KD +  
Sbjct: 481 --CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQ 538

Query: 311 RFDEAQKKALIKKSREL 327
           +  E + +   +K RE+
Sbjct: 539 QEKEKELEKEQEKQREM 555



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 39/144 (27%), Positives = 59/144 (40%), Gaps = 21/144 (14%)

Query: 13  GFKARGTAEDEERDPS-----PVAGPALPPNY-KSSSSDSSDSDEDSSSLYEEGNQESEE 66
           G+ ++    +EE+ P      P  G A PP    +  S +S+         +  +Q  +E
Sbjct: 83  GWASKQEQHEEEKTPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSQFQQE 142

Query: 67  DDSGPTARKQRKNQDDDDDDDDGFFGPAL-PPGFKKQDDSPPRPIIGPALPPGFIKSTQK 125
             S   A  Q K + + +DD+ G  GP+L PP      D       G A       S   
Sbjct: 143 FPSLQAAGDQEKKEKETNDDNYG-PGPSLRPPNVACWRDG------GKA-----AGSPSS 190

Query: 126 SDKGRDDPGQQET--DSSEDEDII 147
           SD+    PGQ E+   +SE  DI+
Sbjct: 191 SDQDEKLPGQDESTAGTSEQNDIL 214


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 8/135 (5%)

Query: 22  DEERDPSPV-AGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQ 80
           DE  +P P+    A+PP    SSS+SS  +  S S  EE  +E EED+      ++ +++
Sbjct: 455 DEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDE------EEEESE 508

Query: 81  DDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDS 140
             D +++       L    +   +       GP   P   K  +K  K +    +    +
Sbjct: 509 SSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPK-RKREKKEKKKKRKAEKHRGRA 567

Query: 141 SEDEDIIGPMPAKGP 155
             DED  GP   + P
Sbjct: 568 GADEDDKGPRAPRPP 582



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 24/102 (23%), Positives = 49/102 (48%), Gaps = 11/102 (10%)

Query: 193 TELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHI 252
           T +PP     GL   + +  ++++S + S  ++   + + + +E +E+  S S+++  H 
Sbjct: 467 TAMPP-----GLAKSSSESSSEESSSESS--SEEEEEEDEEDEEEEESESSDSEEERAHR 519

Query: 253 LSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNK 294
           L+     L EQ+ + +E   + S   I   K K +  E K K
Sbjct: 520 LA----ELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKK 557


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 8/135 (5%)

Query: 22  DEERDPSPV-AGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQ 80
           DE  +P P+    A+PP    SSS+SS  +  S S  EE  +E EED+      ++ +++
Sbjct: 455 DEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDE------EEEESE 508

Query: 81  DDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDS 140
             D +++       L    +   +       GP   P   K  +K  K +    +    +
Sbjct: 509 SSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPK-RKREKKEKKKKRKAEKHRGRA 567

Query: 141 SEDEDIIGPMPAKGP 155
             DED  GP   + P
Sbjct: 568 GADEDDKGPRAPRPP 582



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 24/102 (23%), Positives = 49/102 (48%), Gaps = 11/102 (10%)

Query: 193 TELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHI 252
           T +PP     GL   + +  ++++S + S  ++   + + + +E +E+  S S+++  H 
Sbjct: 467 TAMPP-----GLAKSSSESSSEESSSESS--SEEEEEEDEEDEEEEESESSDSEEERAHR 519

Query: 253 LSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNK 294
           L+     L EQ+ + +E   + S   I   K K +  E K K
Sbjct: 520 LA----ELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKK 557


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 40/142 (28%)

Query: 32  GPALPP----NYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSG---PTARK--------- 75
           G A+P     N K++  + SD +ED  S  +E + E E++D     P A K         
Sbjct: 126 GAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASE 185

Query: 76  ---QRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPI---------IGPALPPGFIKST 123
                 ++DD+DDDDD            ++DDS    +             +P       
Sbjct: 186 DEDDEDDEDDEDDDDD------------EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVA 233

Query: 124 QKSDKGRDDPGQQETDSSEDED 145
           +  D+  DD  + + D  +DED
Sbjct: 234 EDEDEEEDDEDEDDDDDEDDED 255



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 44/192 (22%), Positives = 75/192 (39%), Gaps = 40/192 (20%)

Query: 9   ALPPGFKARGTAEDEERDPSPVA----------GPAL--PPNYKSSSSDSSDSDEDSSSL 56
           A+ PG KA  T   +   P+             G AL   P  K ++  +  +    ++ 
Sbjct: 82  AVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAK 141

Query: 57  YEEGNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALP 116
            E+ ++E E+DDS      +   +DD+D+D+D             +D+  P  +   A  
Sbjct: 142 KEDSDEE-EDDDS------EEDEEDDEDEDED-------------EDEIEPAAMKAAAAA 181

Query: 117 PGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKG-------PVNYNVTTEFEKRAQ 169
           P       + D+  +D    E D SE E+ +   PAKG       PV      E E   +
Sbjct: 182 PASEDEDDEDDEDDEDDDDDEEDDSE-EEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240

Query: 170 RMKEKLTKGDDD 181
             +++    D+D
Sbjct: 241 DDEDEDDDDDED 252



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 68/326 (20%), Positives = 120/326 (36%), Gaps = 25/326 (7%)

Query: 20  AEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEG-NQESEEDDSGPTARKQRK 78
           A   + DP  +A P       S   + S+ +ED SS  E    Q+  +  +  +A+K   
Sbjct: 7   AGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVV 66

Query: 79  NQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQET 138
           +              A+ PG KK   +P +  + PA      K+     K    PG+   
Sbjct: 67  SPTKKVAVATPAKKAAVTPG-KKAAATPAKKTVTPA------KAVTTPGKKGATPGKALV 119

Query: 139 DSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPE 198
            +   +     +PAKG  N     + +   +   +     +DD  +    E      P  
Sbjct: 120 ATPGKKG--AAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDED---EDEDEIEPAA 174

Query: 199 MKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRDK 258
           MK     P +     +D   D     D   D E +A ET  A+   + K    ++  + K
Sbjct: 175 MKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAK----VVPVKAK 230

Query: 259 RLAEQVSSYNESK-----RSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDL-KVNRF 312
            +AE      + +       E   D   +  + +  E++ +P +  P  R K++ K    
Sbjct: 231 NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAA 290

Query: 313 DEAQKKALIKKSRELNTRFSHGKGNM 338
            EA+K+ +  +  E  T F+   GN+
Sbjct: 291 PEAKKQKV--EGTEPTTAFNLFVGNL 314


>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
           [Homo sapiens]
          Length = 845

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 60/309 (19%), Positives = 121/309 (39%), Gaps = 46/309 (14%)

Query: 39  YKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALP-- 96
           ++  + +   + E+   L E+  Q+ ++       R  RK +   D DDDG     +   
Sbjct: 42  FEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERL 101

Query: 97  -----PGFKKQDDSP-PRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPM 150
                P   ++D+ P P+P  G     G + +    D         +++  E+E+   P 
Sbjct: 102 KKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQD---------QSEEEEEEEKHPPK 152

Query: 151 PAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFK 210
           PAK   N       E++   +K K  KG ++ SK         +  P+ K   L      
Sbjct: 153 PAKPEKNRINKAVSEEQQPALKGK--KGKEEKSK--------GKAKPQNKFAAL-----D 197

Query: 211 RRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNES 270
              +D   +     + P   + KAK+ ++  +   + +EE    G  K  A+   ++   
Sbjct: 198 NEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGGESK--ADDPYAHLSK 255

Query: 271 KRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDLKVNRFDEAQKKALIKKSRELN-T 329
           K          KKLK +   ++     +     + D  V++ + + ++A+++ + ++   
Sbjct: 256 KEK--------KKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLENASDIKLE 307

Query: 330 RFS---HGK 335
           +FS   HGK
Sbjct: 308 KFSISAHGK 316


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 17/90 (18%)

Query: 18  GTAEDEERDP-----------SPVAGPALPPNYKSSSSDS----SDSDEDSSSLYEE--G 60
           G++EDE+ D             PV     P    SS SDS    S+ +ED  S  EE  G
Sbjct: 460 GSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSG 519

Query: 61  NQESEEDDSGPTARKQRKNQDDDDDDDDGF 90
           +  SEE +S  +   Q ++Q D++++DD F
Sbjct: 520 SSASEESESEESEDAQSQSQADEEEEDDDF 549


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 62/293 (21%), Positives = 115/293 (39%), Gaps = 31/293 (10%)

Query: 4    DLIGPALPPGFKARGTAED-EERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQ 62
            D +  +LPP     G  +D EE+   P A   +  +++          ++S+     G  
Sbjct: 1108 DDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVVRSSHRPKCRKLPSDPQESTKKSPRGAS 1167

Query: 63   ESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPG-FKKQDDSPPRPIIGPALPPGFIK 121
            +S ++ +G   + + +     +    G    +   G  +K+  S  R  I     P  + 
Sbjct: 1168 DSGKEHNGVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKKAKSSFRDFI-----PVVLS 1222

Query: 122  STQKSDKGR----------DDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRM 171
            +  +S  G            D G QE   +E+E+ + P PAK         + + R+   
Sbjct: 1223 TRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHA 1282

Query: 172  KEK--LTKG--------DDDSSKPIVRESWMT-ELPPEMKDFGLGPRTFKRRADDTSGDR 220
            ++K  L++G        +        R+ W T E   E ++ GL  R  +RR        
Sbjct: 1283 QDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQT 1342

Query: 221  SIW-TDTPADRERKAKETQEAR--KSSSKKDEEHILSGRDKRLAEQVSSYNES 270
              + T+   ++ RK +   +AR  K+SS +  EH L  R+  L  +V   ++S
Sbjct: 1343 GEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRNRNLLLPNKVQGISDS 1395


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 3/135 (2%)

Query: 165 EKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWT 224
           +KR ++ KEK   G   SS     +S  +    E +D   G R  K++        S  +
Sbjct: 79  KKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMS 138

Query: 225 DTPADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNES-KRSESLMDIHHKK 283
           +T +D +   K+ ++++  + K+ +   LS + K  +E     +ES   SE + ++  KK
Sbjct: 139 ETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKK 198

Query: 284 LKSKAAEDKNKPQER 298
            KS  +E++ K  E+
Sbjct: 199 KKS--SEEREKATEK 211



 Score = 36.2 bits (82), Expect = 0.043
 Identities = 39/171 (22%), Positives = 68/171 (39%), Gaps = 21/171 (12%)

Query: 121 KSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDD 180
           K  Q+  K +   G+  + SS   D           + +   E +K+ +R K+K  +   
Sbjct: 79  KKRQRKKKEKKKSGRYSSSSSSSSD-------SSSSSSDSEDEDKKQGKRRKKKKNRSHK 131

Query: 181 DSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEA 240
            S      ES M+E   + KD     +  K+  D T  ++ I       ++RK     + 
Sbjct: 132 SS------ESSMSETESDSKD---SLKKKKKSKDGTEKEKDI---KGLSKKRKMYSEDKP 179

Query: 241 RKSSSKKDEEHI--LSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAA 289
             S S  + E+I  +  + K+ +E+     E  + +     H KK K KAA
Sbjct: 180 LSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 230



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 20/70 (28%)

Query: 39  YKSSSSDSSDSDEDSSSLYEEGNQESE--------------------EDDSGPTARKQRK 78
           Y SSSS SSDS   SS   +E  ++ +                    E DS  + +K++K
Sbjct: 94  YSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKK 153

Query: 79  NQDDDDDDDD 88
           ++D  + + D
Sbjct: 154 SKDGTEKEKD 163


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 3/135 (2%)

Query: 165 EKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWT 224
           +KR ++ KEK   G   SS     +S  +    E +D   G R  K++        S  +
Sbjct: 89  KKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMS 148

Query: 225 DTPADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNES-KRSESLMDIHHKK 283
           +T +D +   K+ ++++  + K+ +   LS + K  +E     +ES   SE + ++  KK
Sbjct: 149 ETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKK 208

Query: 284 LKSKAAEDKNKPQER 298
            KS  +E++ K  E+
Sbjct: 209 KKS--SEEREKATEK 221



 Score = 36.2 bits (82), Expect = 0.043
 Identities = 39/171 (22%), Positives = 68/171 (39%), Gaps = 21/171 (12%)

Query: 121 KSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDD 180
           K  Q+  K +   G+  + SS   D           + +   E +K+ +R K+K  +   
Sbjct: 89  KKRQRKKKEKKKSGRYSSSSSSSSD-------SSSSSSDSEDEDKKQGKRRKKKKNRSHK 141

Query: 181 DSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEA 240
            S      ES M+E   + KD     +  K+  D T  ++ I       ++RK     + 
Sbjct: 142 SS------ESSMSETESDSKD---SLKKKKKSKDGTEKEKDI---KGLSKKRKMYSEDKP 189

Query: 241 RKSSSKKDEEHI--LSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAA 289
             S S  + E+I  +  + K+ +E+     E  + +     H KK K KAA
Sbjct: 190 LSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAA 240



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 20/70 (28%)

Query: 39  YKSSSSDSSDSDEDSSSLYEEGNQESE--------------------EDDSGPTARKQRK 78
           Y SSSS SSDS   SS   +E  ++ +                    E DS  + +K++K
Sbjct: 104 YSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKK 163

Query: 79  NQDDDDDDDD 88
           ++D  + + D
Sbjct: 164 SKDGTEKEKD 173


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
           [Homo sapiens]
          Length = 2059

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 50/243 (20%), Positives = 87/243 (35%), Gaps = 40/243 (16%)

Query: 48  DSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDS-- 105
           + +E+   + EE  +E EE D       +  ++DD++DDD+G  G    PG  +  D   
Sbjct: 9   EEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRG--PGHDRGRDRHS 66

Query: 106 -------PPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNY 158
                  PP P   P LPP                         D+D I  +P+   V  
Sbjct: 67  PPGCHLFPPPPPPPPPLPP------------------PPPPPPPDKDDIRLLPSALGVKK 108

Query: 159 NVTTEFEKRAQR--MKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDT 216
                 +++  +     K  K D +      R+ +  +      ++G GP   +RR    
Sbjct: 109 RKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHRE 168

Query: 217 SGDRSIWTDTPADRERKAKETQEARKSSSK-------KDEEHILSGRDKRLAEQVSSYNE 269
             ++   T      E    + Q  +KSS+        +D EH+ S  D        ++++
Sbjct: 169 KKEKK--TKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQ 226

Query: 270 SKR 272
             R
Sbjct: 227 FMR 229



 Score = 35.4 bits (80), Expect = 0.074
 Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 21   EDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEED-DSGPTARKQRKN 79
            E ++ D +   G       + + +D++  D+D+ S Y  G++E +ED D  P  R+Q K 
Sbjct: 1386 EQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKR 1445

Query: 80   QDDDDDD 86
            Q  ++ D
Sbjct: 1446 QLRNEKD 1452



 Score = 28.5 bits (62), Expect = 9.0
 Identities = 41/200 (20%), Positives = 69/200 (34%), Gaps = 34/200 (17%)

Query: 21  EDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEE-DDSGPTARKQRKN 79
           E+EE +   V+        +    +  + DE+     E  +++ EE DD G   R    +
Sbjct: 8   EEEEEEEMVVS--------EEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHD 59

Query: 80  QDDDDDDDDG--FFGPALPPGFKKQDDSPPRP-------IIGPAL--------------- 115
           +  D     G   F P  PP        PP P       ++  AL               
Sbjct: 60  RGRDRHSPPGCHLFPPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKEN 119

Query: 116 PPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKL 175
            PG  +  +K D   ++ G +  +  E  +  G     GP         EK+ ++ K + 
Sbjct: 120 KPGKPRKRKKRD-SEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRK 178

Query: 176 TKGDDDSSKPIVRESWMTEL 195
               D   K + ++S  T L
Sbjct: 179 KGEGDGGQKQVEQKSSATLL 198


>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
          Length = 1173

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 52/221 (23%), Positives = 84/221 (38%), Gaps = 42/221 (19%)

Query: 62   QESEEDDSGPTARKQRKNQ---DDDDDDDDGFFGPA----LPPGFKKQDDSPPRPIIGPA 114
            QE E+++ G   +K+R+     ++  DDD+   GP      PP  K +    P+P   P 
Sbjct: 945  QEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPP--KAEKKKAPKPERLPP 1002

Query: 115  LPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEK 174
               G IKS               +D S DED +       P N N  ++ ++  QR K  
Sbjct: 1003 SMKGKIKSKAIISS---------SDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCA 1053

Query: 175  LTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKA 234
             ++ D D ++             +       PR  +R+  D   D    +D P+ + R +
Sbjct: 1054 SSESDSDENQ------------NKSGSEAGSPRRPRRQRSDQDSD----SDQPSRKRRPS 1097

Query: 235  KETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSES 275
                     S + D E + SGR      +  S   S  +ES
Sbjct: 1098 --------GSEQSDNESVQSGRSHSGVSENDSRPASPSAES 1130



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 42/147 (28%), Positives = 57/147 (38%), Gaps = 21/147 (14%)

Query: 11   PPGFKARGTAEDEERDPSPVAGPALPPNYKS--------SSSDSSDSDEDSSSLYEEG-- 60
            P   K R    ++++ P P     LPP+ K         SSSD S SDED   + +EG  
Sbjct: 979  PKPKKRRPPKAEKKKAPKP---ERLPPSMKGKIKSKAIISSSDDS-SDEDKLKIADEGHP 1034

Query: 61   -NQESEEDDSGPTARKQRKNQDDDDDDDDGFFG-----PALPPGFKKQDDSPPRPIIGPA 114
             N  S  D      RK+  + + D D++    G     P  P   +   DS         
Sbjct: 1035 RNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKR 1094

Query: 115  LPPGFIKSTQKS-DKGRDDPGQQETDS 140
             P G  +S  +S   GR   G  E DS
Sbjct: 1095 RPSGSEQSDNESVQSGRSHSGVSENDS 1121


>gi|59814411 hypothetical protein LOC253725 [Homo sapiens]
          Length = 1318

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 54/256 (21%), Positives = 90/256 (35%), Gaps = 46/256 (17%)

Query: 79  NQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQET 138
           + DD DDDDD F  P   P                         T+K     D  G +E 
Sbjct: 452 DDDDGDDDDDFFSAPHSKP-----------------------SKTRKVQSTADIFGDEEG 488

Query: 139 DSSEDEDIIGPMPAKGPVNYN-------VTTEFEKRAQRMKEKLTKGDDDSSKPIVRESW 191
           D  +++ +  P       + N       VT  + K  +   E  T+    S +    + +
Sbjct: 489 DLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLF 548

Query: 192 MTELPPEMKDFGLGP---RTFKRRADDTSGDRSIWTDT---------PADRERKAKETQE 239
            ++    +K   L P    T     DD   + +++  T          A RE KAK ++ 
Sbjct: 549 SSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASEL 608

Query: 240 ARKSSS----KKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKP 295
           ++K +S      DEE  +      LA    S  E + S +L     K +K  +  +++K 
Sbjct: 609 SKKKASALLFSSDEEWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKE 668

Query: 296 QERIPFDRDKDLKVNR 311
            +     +D   K  R
Sbjct: 669 DDLFAIAKDSQKKTQR 684



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 52/228 (22%), Positives = 83/228 (36%), Gaps = 38/228 (16%)

Query: 41  SSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQ-----DDDDDDDDGFFGPAL 95
           SS   S  SD  S    EE  +E E D+         +NQ      D+++DDDG      
Sbjct: 205 SSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGC--DLF 262

Query: 96  PPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGP 155
               K+++D               I+   +  + R      E  +    D +G +  +  
Sbjct: 263 ADSEKEEEDIED------------IEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPT 310

Query: 156 VNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKD-----FGLGPRTF- 209
              +   +  K  +  KE+ T  DD+              PP++ D     FG G   F 
Sbjct: 311 TLPSGEAKPRKTLKEKKERRTPSDDEEDNLFA--------PPKLTDEDFSPFGSGGGLFS 362

Query: 210 --KRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSG 255
             K   DD   +  ++T+   DR+  A   +E   SSS K  + I +G
Sbjct: 363 GGKGLFDDEDEESDLFTEASQDRQAGASVKEE---SSSSKPGKKIPAG 407


>gi|16904383 leucine rich repeat containing 7 [Homo sapiens]
          Length = 1537

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 74/324 (22%), Positives = 116/324 (35%), Gaps = 47/324 (14%)

Query: 24  ERDPSPVAGPALPPNY------KSSSSDSSDSDED-------SSSLYEEGNQESEEDDSG 70
           E  PS    P  PP        K  S+D S+ D+        SS  Y + +       S 
Sbjct: 641 ELHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSGSS 700

Query: 71  PTARKQRKNQDDDDDD-DDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKG 129
            T  K    Q    D   +  +G  + P F +  DS P      A+PPG I         
Sbjct: 701 NTRVKVGSLQTTAKDAVHNSLWGNRIAPSFPQPLDSKPLLSQREAVPPGNIPQRPDRLPM 760

Query: 130 RDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRE 189
            D      TD S  ++        G V    T E       +  K         +P++R+
Sbjct: 761 SDTFTDNWTDGSHYDN-------TGFVAEETTAENANSNPLLSSKSRSTSSHGRRPLIRQ 813

Query: 190 SWMTELPPEMKDFGLGPRTFKRRADDT----SGDRSIWTDTPADRERK----AKETQEAR 241
             +  +P E++      ++  R   +T    S     WT TP+  E +    +K      
Sbjct: 814 DRIVGVPLELE------QSTHRHTPETEVPPSNPWQNWTRTPSPFEDRTAFPSKLETTPT 867

Query: 242 KSSSKKDEEHILSGRDKRLAEQVS-----SYNESKRSESLMD----IHHKKLKSKAAEDK 292
            S   + +EHI    +  +    S      Y++S  + SL +    IH +   SK     
Sbjct: 868 TSPLPERKEHIKESTE--IPSPFSPGVPWEYHDSNPNRSLSNVFSQIHCRPESSKGVISI 925

Query: 293 NKPQERIPFDRDKDLKVNRFDEAQ 316
           +K  ER+     KD+K N+F ++Q
Sbjct: 926 SKSTERLS-PLMKDIKSNKFKKSQ 948


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 73/340 (21%), Positives = 115/340 (33%), Gaps = 64/340 (18%)

Query: 23  EERDPSPVAGPALP-PNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQD 81
           E   P P   PA   P    S  D    D    S  E+     +E   G  A +Q     
Sbjct: 369 EAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQ----- 423

Query: 82  DDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDD--------- 132
           D D D +   G  +  GF+   D   +P   P LP G + S   +    ++         
Sbjct: 424 DSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKG 483

Query: 133 --PGQQETDSSEDE--DIIGPMPAKG-----------PVNYNVTTEFEKRAQRMK----- 172
             P  Q+    E +   I    P +G           P   +V T  EKR+         
Sbjct: 484 PAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEME 543

Query: 173 ----EKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADD--TSGDRSIWTD- 225
               E+ +  + D   PI  +  M     +  DF       +RRADD     D S  TD 
Sbjct: 544 PGKGEQASSSESDPEGPIAAQ--MLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDE 601

Query: 226 --------------TPADRERKAKE------TQEARKSSSKKDEEHILSGRDKRLAEQVS 265
                          PA R +   +       +   K SS++ +E     ++K+  ++  
Sbjct: 602 DEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKG 661

Query: 266 SYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDK 305
              E K ++        K K +  E++ + Q+R P  R++
Sbjct: 662 KEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRER 701


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 58/280 (20%), Positives = 111/280 (39%), Gaps = 22/280 (7%)

Query: 59  EGNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALP-PGFKKQD------DSPPRPII 111
           E N  S+E DS P  +K+ K +D           P +P P   K+D      +   R +I
Sbjct: 221 ELNAPSQESDSHPRKKKKEKKEDIFRRFP---VAPLIPYPLITKEDINAIEMEEDKRDLI 277

Query: 112 GPALPPGFIKSTQKS---DKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRA 168
              +     + T K    +KG+ +  +QE +    E        +         E E+  
Sbjct: 278 SREISK--FRDTHKKLEEEKGKKEKERQEIEKERRER------ERERERERERRERERER 329

Query: 169 QRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPA 228
           +R +E+  + + +  +   R+   T+     +D        + R+ D + DRS   +   
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389

Query: 229 DRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIH-HKKLKSK 287
           DRER+ +  +E  +   ++ E      R++    +     +  R E   D +  +KL+ K
Sbjct: 390 DREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449

Query: 288 AAEDKNKPQERIPFDRDKDLKVNRFDEAQKKALIKKSREL 327
             E +   QER+     ++ K  R  E + +   ++ RE+
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREM 489


>gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo
           sapiens]
          Length = 625

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 11/126 (8%)

Query: 1   MARDLIGPALPPGFKA---RGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLY 57
           +AR+      PP   A     TA + + D  P AG     N   S + S DSD DS S  
Sbjct: 470 LAREREEKEQPPQLSASMPETTATEPQPDDEPAAGVQ---NGAPSPAPSPDSDSDSDSDG 526

Query: 58  EEGNQESEEDDSGPTARKQRKNQDDDDDD---DDGFFGPALPPGFKKQD--DSPPRPIIG 112
           EE  +E  E D  P+     ++    +     +    GP LP G K +     PP P  G
Sbjct: 527 EEEEEEEGERDETPSGAIDTRDTGSSEPQPPPEPPRSGPPLPNGLKPEFALALPPEPPPG 586

Query: 113 PALPPG 118
           P +  G
Sbjct: 587 PEVKGG 592


>gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo
           sapiens]
          Length = 625

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 11/126 (8%)

Query: 1   MARDLIGPALPPGFKA---RGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLY 57
           +AR+      PP   A     TA + + D  P AG     N   S + S DSD DS S  
Sbjct: 470 LAREREEKEQPPQLSASMPETTATEPQPDDEPAAGVQ---NGAPSPAPSPDSDSDSDSDG 526

Query: 58  EEGNQESEEDDSGPTARKQRKNQDDDDDD---DDGFFGPALPPGFKKQD--DSPPRPIIG 112
           EE  +E  E D  P+     ++    +     +    GP LP G K +     PP P  G
Sbjct: 527 EEEEEEEGERDETPSGAIDTRDTGSSEPQPPPEPPRSGPPLPNGLKPEFALALPPEPPPG 586

Query: 113 PALPPG 118
           P +  G
Sbjct: 587 PEVKGG 592


>gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo
           sapiens]
          Length = 625

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 11/126 (8%)

Query: 1   MARDLIGPALPPGFKA---RGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLY 57
           +AR+      PP   A     TA + + D  P AG     N   S + S DSD DS S  
Sbjct: 470 LAREREEKEQPPQLSASMPETTATEPQPDDEPAAGVQ---NGAPSPAPSPDSDSDSDSDG 526

Query: 58  EEGNQESEEDDSGPTARKQRKNQDDDDDD---DDGFFGPALPPGFKKQD--DSPPRPIIG 112
           EE  +E  E D  P+     ++    +     +    GP LP G K +     PP P  G
Sbjct: 527 EEEEEEEGERDETPSGAIDTRDTGSSEPQPPPEPPRSGPPLPNGLKPEFALALPPEPPPG 586

Query: 113 PALPPG 118
           P +  G
Sbjct: 587 PEVKGG 592


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 63/296 (21%), Positives = 120/296 (40%), Gaps = 54/296 (18%)

Query: 42   SSSDSSDSDEDSSSLYEEGNQESEE-----------------DDSGPTARKQRKNQDDDD 84
            +SS SSD ++D  +   EG+ + ++                   SG  A  +      DD
Sbjct: 1163 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1222

Query: 85   DDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDK---GRDDPGQ-QETDS 140
            DDDD                + P   I   +    IK+   SD+     D+P + ++   
Sbjct: 1223 DDDD----------------NDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTG 1266

Query: 141  SEDEDIIGPMPAKGPVNYNVTTEFEK------RAQRMKEKLTKGDDDSSKPIVRESWMTE 194
             ++E+  G   AK  VN    ++ E+      R + ++ KLT  D +S      E   T+
Sbjct: 1267 KQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG-----EEKKTK 1321

Query: 195  LPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKD--EEHI 252
             P E K+  +  R  ++ + + S D        ++   ++++ Q  R  S+KK   EE+ 
Sbjct: 1322 -PKEHKE--VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQ 1378

Query: 253  LSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDLK 308
             S + K+   ++    E   SE+  +   ++ + +  E++ + +E    D + D K
Sbjct: 1379 RSYKQKKKRRRI-KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSK 1433



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 61/280 (21%), Positives = 111/280 (39%), Gaps = 55/280 (19%)

Query: 47   SDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDD------GFFGPALPPGFK 100
            +++ E S  L  +  ++ ++  S    +  +K+Q D+  +DD      G      P  FK
Sbjct: 902  AETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFK 961

Query: 101  KQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNV 160
            K+                 IK  Q+ +   D      T+   + + I   P       N 
Sbjct: 962  KK----------------VIKMEQQYESSSDG-----TEKLPEREEICHFPKGIKQIKNG 1000

Query: 161  TTEFEKRAQRMKEKLTKGDD----------------DSSKPIVRESWMTELPPEMKDFGL 204
            TT+ EK+++++++K +K  D                DSS+   ++S       E K   L
Sbjct: 1001 TTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSED--KKSKNGAYGREKKRCKL 1058

Query: 205  GPRTFKRRADDTSGDRSIWTD-----TPADRERKAKETQEARKSSSKKDEEHILSGRDKR 259
              ++ ++R D +S D   ++        +D+  K  E +E R  SSK++ + I SG    
Sbjct: 1059 LGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSS 1118

Query: 260  LAEQVSSYNESKR-----SESLMDIHHKKLKSKAAEDKNK 294
             AE+ S  N+ K+      +  + +  KK  S     K K
Sbjct: 1119 DAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1158



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 46/282 (16%), Positives = 122/282 (43%), Gaps = 28/282 (9%)

Query: 21   EDEERDP-SPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKN 79
            +D++ DP + +A   L    K++ S  SD D  S    EEG + + + +      ++ KN
Sbjct: 1223 DDDDNDPENRIAKKMLLEEIKANLS--SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKN 1280

Query: 80   QDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETD 139
            Q + + D D             ++   PR           ++       G +   +++T 
Sbjct: 1281 QVNSESDSD------------SEESKKPR------YRHRLLRHKLTVSDG-ESGEEKKTK 1321

Query: 140  SSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEM 199
              E +++ G    K     +  ++F++    + E++++ +D+  +P  R +   EL    
Sbjct: 1322 PKEHKEVKGRNRRKVSSEDSEDSDFQESG--VSEEVSESEDE-QRPRTRSAKKAELEENQ 1378

Query: 200  KDFGLGP--RTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRD 257
            + +      R  K + D +S ++S   +   ++E + +E +E  +    ++++    G+ 
Sbjct: 1379 RSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG 1438

Query: 258  KRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERI 299
            ++   ++   ++  R+E+   +  ++ + K   ++ + +E++
Sbjct: 1439 RKKIRKILK-DDKLRTETQNALKEEEERRKRIAEREREREKL 1479



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 5/74 (6%)

Query: 20   AEDEERDPSPVAGPA-LPPNYKSSSSDSSDS----DEDSSSLYEEGNQESEEDDSGPTAR 74
            +EDE+R  +  A  A L  N +S             EDSSS  +  ++E EE+       
Sbjct: 1358 SEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEE 1417

Query: 75   KQRKNQDDDDDDDD 88
            ++ + ++++D++DD
Sbjct: 1418 EEEEEEEEEDENDD 1431



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 11/83 (13%)

Query: 14  FKARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTA 73
           F A  + E EE    P        +  S S  +SD  E+S    EEG   SE+  S  ++
Sbjct: 21  FLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSK---EEGTSSSEKSKSSGSS 77

Query: 74  RKQRK--------NQDDDDDDDD 88
           R +RK          DD+   DD
Sbjct: 78  RSKRKPSIVTKYVESDDEKPLDD 100


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 63/296 (21%), Positives = 120/296 (40%), Gaps = 54/296 (18%)

Query: 42   SSSDSSDSDEDSSSLYEEGNQESEE-----------------DDSGPTARKQRKNQDDDD 84
            +SS SSD ++D  +   EG+ + ++                   SG  A  +      DD
Sbjct: 1201 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1260

Query: 85   DDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDK---GRDDPGQ-QETDS 140
            DDDD                + P   I   +    IK+   SD+     D+P + ++   
Sbjct: 1261 DDDD----------------NDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTG 1304

Query: 141  SEDEDIIGPMPAKGPVNYNVTTEFEK------RAQRMKEKLTKGDDDSSKPIVRESWMTE 194
             ++E+  G   AK  VN    ++ E+      R + ++ KLT  D +S      E   T+
Sbjct: 1305 KQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG-----EEKKTK 1359

Query: 195  LPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKD--EEHI 252
             P E K+  +  R  ++ + + S D        ++   ++++ Q  R  S+KK   EE+ 
Sbjct: 1360 -PKEHKE--VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQ 1416

Query: 253  LSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDLK 308
             S + K+   ++    E   SE+  +   ++ + +  E++ + +E    D + D K
Sbjct: 1417 RSYKQKKKRRRI-KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSK 1471



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 61/280 (21%), Positives = 111/280 (39%), Gaps = 55/280 (19%)

Query: 47   SDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDD------GFFGPALPPGFK 100
            +++ E S  L  +  ++ ++  S    +  +K+Q D+  +DD      G      P  FK
Sbjct: 940  AETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFK 999

Query: 101  KQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNV 160
            K+                 IK  Q+ +   D      T+   + + I   P       N 
Sbjct: 1000 KK----------------VIKMEQQYESSSDG-----TEKLPEREEICHFPKGIKQIKNG 1038

Query: 161  TTEFEKRAQRMKEKLTKGDD----------------DSSKPIVRESWMTELPPEMKDFGL 204
            TT+ EK+++++++K +K  D                DSS+   ++S       E K   L
Sbjct: 1039 TTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSED--KKSKNGAYGREKKRCKL 1096

Query: 205  GPRTFKRRADDTSGDRSIWTD-----TPADRERKAKETQEARKSSSKKDEEHILSGRDKR 259
              ++ ++R D +S D   ++        +D+  K  E +E R  SSK++ + I SG    
Sbjct: 1097 LGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSS 1156

Query: 260  LAEQVSSYNESKR-----SESLMDIHHKKLKSKAAEDKNK 294
             AE+ S  N+ K+      +  + +  KK  S     K K
Sbjct: 1157 DAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1196



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 46/282 (16%), Positives = 122/282 (43%), Gaps = 28/282 (9%)

Query: 21   EDEERDP-SPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKN 79
            +D++ DP + +A   L    K++ S  SD D  S    EEG + + + +      ++ KN
Sbjct: 1261 DDDDNDPENRIAKKMLLEEIKANLS--SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKN 1318

Query: 80   QDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETD 139
            Q + + D D             ++   PR           ++       G +   +++T 
Sbjct: 1319 QVNSESDSD------------SEESKKPR------YRHRLLRHKLTVSDG-ESGEEKKTK 1359

Query: 140  SSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEM 199
              E +++ G    K     +  ++F++    + E++++ +D+  +P  R +   EL    
Sbjct: 1360 PKEHKEVKGRNRRKVSSEDSEDSDFQESG--VSEEVSESEDE-QRPRTRSAKKAELEENQ 1416

Query: 200  KDFGLGP--RTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRD 257
            + +      R  K + D +S ++S   +   ++E + +E +E  +    ++++    G+ 
Sbjct: 1417 RSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG 1476

Query: 258  KRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERI 299
            ++   ++   ++  R+E+   +  ++ + K   ++ + +E++
Sbjct: 1477 RKKIRKILK-DDKLRTETQNALKEEEERRKRIAEREREREKL 1517



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 43/182 (23%), Positives = 64/182 (35%), Gaps = 41/182 (22%)

Query: 14  FKARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTA 73
           F A  + E EE    P        +  S S  +SD  E+S    EEG   SE+  S  ++
Sbjct: 21  FLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSK---EEGTSSSEKSKSSGSS 77

Query: 74  RKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDP 133
           R +RK              P++   + + DD  P       L    +     ++   +D 
Sbjct: 78  RSKRK--------------PSIVTKYVESDDEKP-------LDDETVNEDASNENSENDI 116

Query: 134 GQQETDSSEDEDIIGPMPA--------KGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKP 185
             Q     +   I+ P P         KGP       EF  R++   E L K  +D    
Sbjct: 117 TMQSL--PKGTVIVQPEPVLNEDKDDFKGP-------EFRSRSKMKTENLKKRGEDGLHG 167

Query: 186 IV 187
           IV
Sbjct: 168 IV 169



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 5/74 (6%)

Query: 20   AEDEERDPSPVAGPA-LPPNYKSSSSDSSDS----DEDSSSLYEEGNQESEEDDSGPTAR 74
            +EDE+R  +  A  A L  N +S             EDSSS  +  ++E EE+       
Sbjct: 1396 SEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEE 1455

Query: 75   KQRKNQDDDDDDDD 88
            ++ + ++++D++DD
Sbjct: 1456 EEEEEEEEEDENDD 1469


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.128    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,235,595
Number of Sequences: 37866
Number of extensions: 938670
Number of successful extensions: 8743
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 233
Number of HSP's successfully gapped in prelim test: 510
Number of HSP's that attempted gapping in prelim test: 5399
Number of HSP's gapped (non-prelim): 2495
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.