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Search of human proteins with 33286444
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33286444 mastermind-like 2 [Homo sapiens]
(1156 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33286444 mastermind-like 2 [Homo sapiens] 2323 0.0
gi|38158015 mastermind-like 3 [Homo sapiens] 252 2e-66
gi|7661990 mastermind-like 1 [Homo sapiens] 184 4e-46
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 142 2e-33
gi|110347429 mediator complex subunit 12 [Homo sapiens] 139 2e-32
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 127 8e-29
gi|221139761 zinc finger protein 853 [Homo sapiens] 117 6e-26
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 114 5e-25
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 113 9e-25
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 113 9e-25
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 113 9e-25
gi|120952764 mastermind-like domain containing 1 [Homo sapiens] 107 5e-23
gi|93141033 PAX interacting protein 1 [Homo sapiens] 99 3e-20
gi|226246533 TOX high mobility group box family member 3 isoform... 97 7e-20
gi|226054295 TOX high mobility group box family member 3 isoform... 97 7e-20
gi|4507379 TATA box binding protein [Homo sapiens] 94 6e-19
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 91 5e-18
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 90 1e-17
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 90 1e-17
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 87 7e-17
gi|119943102 CREB binding protein isoform b [Homo sapiens] 87 7e-17
gi|119943104 CREB binding protein isoform a [Homo sapiens] 87 7e-17
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 87 9e-17
gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 87 1e-16
gi|56549696 E1A binding protein p400 [Homo sapiens] 85 3e-16
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 84 1e-15
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 84 1e-15
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 84 1e-15
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 84 1e-15
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 84 1e-15
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 2323 bits (6019), Expect = 0.0
Identities = 1156/1156 (100%), Positives = 1156/1156 (100%)
Query: 1 MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER 60
MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER
Sbjct: 1 MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER 60
Query: 61 GRAESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAA 120
GRAESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAA
Sbjct: 61 GRAESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAA 120
Query: 121 TAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQ 180
TAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQ
Sbjct: 121 TAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQ 180
Query: 181 VVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPL 240
VVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPL
Sbjct: 181 VVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPL 240
Query: 241 RKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQ 300
RKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQ
Sbjct: 241 RKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQ 300
Query: 301 LMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPME 360
LMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPME
Sbjct: 301 LMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPME 360
Query: 361 KIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGA 420
KIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGA
Sbjct: 361 KIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGA 420
Query: 421 SRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKI 480
SRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKI
Sbjct: 421 SRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKI 480
Query: 481 PSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRS 540
PSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRS
Sbjct: 481 PSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRS 540
Query: 541 FINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQ 600
FINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQ
Sbjct: 541 FINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQ 600
Query: 601 QQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQ 660
QQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 601 QQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQ 660
Query: 661 QQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVG 720
QQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVG
Sbjct: 661 QQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVG 720
Query: 721 QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLAD 780
QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLAD
Sbjct: 721 QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLAD 780
Query: 781 AEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHT 840
AEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHT
Sbjct: 781 AEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHT 840
Query: 841 ILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLL 900
ILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLL
Sbjct: 841 ILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLL 900
Query: 901 ANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSN 960
ANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSN
Sbjct: 901 ANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSN 960
Query: 961 TTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQL 1020
TTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQL
Sbjct: 961 TTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQL 1020
Query: 1021 TPAVQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPP 1080
TPAVQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPP
Sbjct: 1021 TPAVQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPP 1080
Query: 1081 SLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPGND 1140
SLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPGND
Sbjct: 1081 SLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPGND 1140
Query: 1141 DWMKDINLDEILGNNS 1156
DWMKDINLDEILGNNS
Sbjct: 1141 DWMKDINLDEILGNNS 1156
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 252 bits (643), Expect = 2e-66
Identities = 323/1267 (25%), Positives = 483/1267 (38%), Gaps = 293/1267 (23%)
Query: 5 APPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYERGRAE 64
A P + GG G+G GGGS HS +VERLR RI CR+HH++CE RY++ + E
Sbjct: 42 AAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVE 101
Query: 65 SSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAATAAP 124
+ ER T+ L Q A+K+G T P+ P ++AA+
Sbjct: 102 QLELERRDTVSLYQRTLE-QRAKKSG----------AGTGKQQHPSKPQQDAEAAS---- 146
Query: 125 PPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQVVNL 184
+QRN LI LQ ++KRK
Sbjct: 147 -------------------------------------AEQRNHTLIMLQETVKRKLEGAR 169
Query: 185 SPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQI-MSGTLPMSQAPLRKT 243
SP N + NG D +F + R+ +++SAG INN S + + P+ Q L+ +
Sbjct: 170 SPLNGDQQNGACDGNFSPTSK-RIRKDISAGMEA--INNLPSNMPLPSASPLHQLDLKPS 226
Query: 244 NTLP-SHTHSPG------------------NGLFN-------MGLKEVKKEPGETLSCSK 277
L S TH+PG NG + + K++K+EP + +C
Sbjct: 227 LPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCID 286
Query: 278 HMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIKQD 337
+ ++ +N + D L D E QEL +EL N P D++
Sbjct: 287 TSETSLSNQN---KLFSD---INLNDQEWQELIDELAN--TVPEDDIQ------------ 326
Query: 338 DPFNIDLGQQSQRSTPRPS----LPMEKIVIKSE--YSPGLTQGPSGSPQLRPPSAGPAF 391
D FN D ++ + +P+ L E +KS+ +SP GSPQ RP S+GP F
Sbjct: 327 DLFNEDFEEKKEPEFSQPATETPLSQESASVKSDPSHSP-FAHVSMGSPQARPSSSGPPF 385
Query: 392 SMANSALS-------------TSSPIPSVPQS-----------QAQPQTGSG-------- 419
S ++A S SSP QS QA P+ G+G
Sbjct: 386 STVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAV 445
Query: 420 -------ASRALPSWQEVSHAQQLKQIAANRQQHARM-------------------QQHQ 453
A+PS ++S A+QLKQ+AA +QQ A++ QQ Q
Sbjct: 446 TVAGSASGPVAVPS-SDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ 504
Query: 454 QQH--QPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMA 511
QQH Q +NWS L + P F EK SP Q F+ Q+ +P +A Q M
Sbjct: 505 QQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNL-QKTTMN 563
Query: 512 NYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQM 571
NY+ + H++++ QQ P +L + +N H + GNTKPL HFN+D + +
Sbjct: 564 NYLPQ-------NHMNMINQQ-PNNLGTNSLNKQHNIL--TYGNTKPLTHFNADLSQRMT 613
Query: 572 PSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQ 631
P V P + + QQQQQQQQQQQQQQQQQ Q Q + + Q + +Q+
Sbjct: 614 PPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKG 673
Query: 632 QQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQP------------------SSQPAQS 673
+ A Q+Q + Q P SQP +
Sbjct: 674 VMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAA 733
Query: 674 LPSQPLL--RSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNP 731
+ Q L+ R+ L QQK + Q Q +++QQ Q H + Q+ P +P P
Sbjct: 734 IMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSH-LPRQHLQPQRNPYP 792
Query: 732 CSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQIN 791
N G ++ +Q + +T + + Q A Q ++
Sbjct: 793 VQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATAAAQSEM- 851
Query: 792 RHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLST 851
+ T G +S Q L +P + +T N
Sbjct: 852 ---------------GLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQ----- 891
Query: 852 SHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRP 911
+ G R P+ V + +G + V S +TQQ + Q P P
Sbjct: 892 AQGPRQPASGQGVGMVSGFG-------QSMLVNSA---ITQQHPQMKGPVGQALPRPQAP 941
Query: 912 PTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTA--PNWASQ 969
P L +G QQ + P RTS + N A P A Q
Sbjct: 942 PRL------------QSLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQ 989
Query: 970 EGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPM 1029
+KQ FP G SQ L PA R
Sbjct: 990 PRLTKQ---------HFPQGL---------------SQSVVDANTGTVRTLNPAAMGR-- 1023
Query: 1030 NQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPS--LTPSNF 1087
QM +L GQ +Q ++ L+Q G+ +QPP+ PS
Sbjct: 1024 -QMMPSLPGQQ---------GTSQARPMVMSGLSQGVPGM----PAFSQPPAQQQIPSGS 1069
Query: 1088 PSPNQSSRAFQGTDHSSDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPGNDDWMKDIN 1147
+P+ S+A++ + D+++++ P L AD +DS++K PG D+WM++
Sbjct: 1070 FAPSSQSQAYE-RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPG-DEWMQE-- 1125
Query: 1148 LDEILGN 1154
LDE+ GN
Sbjct: 1126 LDELFGN 1132
>gi|7661990 mastermind-like 1 [Homo sapiens]
Length = 1016
Score = 184 bits (467), Expect = 4e-46
Identities = 274/974 (28%), Positives = 387/974 (39%), Gaps = 194/974 (19%)
Query: 33 HSAIVERLRARIAVCRQHHLSCEGRYERGRAESSDRERESTLQLLSLVQHGQGARKAGKH 92
HSA++ERLR RI +CR+HH +CE RYE E + ER+ T L + A++AGKH
Sbjct: 16 HSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAK-AKRAGKH 74
Query: 93 TKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGING 152
+ A A P PAAP AA P + H + L+S+ + +
Sbjct: 75 RQPPAATA------PAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATSPQN----- 123
Query: 153 EQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENL 212
GDQ+N G K ++ L A S NG S L +
Sbjct: 124 ---------GDQQNGYGDLFPGHKKTRREAPLGVAISS--NGLPPASPLG------QSDK 166
Query: 213 SAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNG----LFNMGL-KEVKK 267
+G LQ SG + L K S H G F + L KE+K+
Sbjct: 167 PSGADALQ--------SSGKHSLGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQ 218
Query: 268 EPGETLSCS-KHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLEL 326
EP E L C G ++Q N+ P+ L + E +EL EL N SVP D ++
Sbjct: 219 EPVEDLPCMITGTVGSISQSNLMPDL-------NLNEQEWKELIEEL-NRSVP---DEDM 267
Query: 327 ENMINATIKQ-DDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSP-GLTQGPSGSPQLRP 384
+++ N ++ DP + S +T P + I IK+E+SP Q GSPQ+R
Sbjct: 268 KDLFNEDFEEKKDP------ESSGSATQTPL--AQDINIKTEFSPAAFEQEQLGSPQVRA 319
Query: 385 PSAGPAFSMANSA-LSTSS--------------------PIPSVPQSQAQPQTGSG--AS 421
SAG F +SA +ST S P P++ + AQ Q A
Sbjct: 320 GSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAG 379
Query: 422 RALPSW-----QEVSHAQQLKQIAANRQQHARMQQHQQQHQP-------TNWSALPSSAG 469
LPS E+S A QL+QIAA +Q+ +M Q+ QQ P + W S
Sbjct: 380 VVLPSQGPGGASELSSAHQLQQIAA-KQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHS 438
Query: 470 PSPGPFGQEKIPSPSFGQQTF-SPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDV 528
P+ EK SPS +Q F + + MP V S + GP Q H+++
Sbjct: 439 SLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPR---------PGGPYLQPSHVNL 489
Query: 529 LMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQ 588
L Q P +L+++ NN ++ GNTKPL H+ +D Q P Q+KP+L+ Y
Sbjct: 490 LSHQPPSNLNQNSANNQGSVLD--YGNTKPLSHYKAD-CGQGSPG--SGQSKPALMAYLP 544
Query: 589 QQQQQQQQQQQQ--------------------QQQQQQQQQQQQQQQQQQQQQSSISAQQ 628
QQ +Q Q+Q Q Q Q ++S
Sbjct: 545 QQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVAS 604
Query: 629 QQQQQSSISAQQQ------------QQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPS 676
+S+QQQ QQ+Q++QQQ+ QQQQ Q+QQ + Q Q
Sbjct: 605 SHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQF-- 662
Query: 677 QPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNT-GPSPSPNPCSNP 735
Q L P P Q P G Q Q +V G NT GPS S P P
Sbjct: 663 QRHLTRPPPQYQ---------DPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFP 713
Query: 736 NTGS--------GYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQ 787
G+ ++S + QQ G Q Q M Q + + + PQ
Sbjct: 714 QAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQ 773
Query: 788 DQINRHLSRPPPDYKDQRRNVG-NMQPTAQY---SGGSSTISLNSNQALANPVSTHTILT 843
N H P ++ NVG N +A Y S GSS +S N+ NP T
Sbjct: 774 -ATNGHAHIP------RQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLT----K 822
Query: 844 PNSSLLSTSHGTRMPSLSTAVQNMGM---YGNLPCN---QPNTYSVTSGMNQLT--QQRN 895
P +S + G + +++ Q+ GM G P N P T + + M Q + +
Sbjct: 823 PPVPRVSPAMGGQ----NSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSS 878
Query: 896 PKQLLANQNNPMMP 909
P+ A N PM P
Sbjct: 879 PQFSQAVPNRPMAP 892
Score = 31.6 bits (70), Expect = 4.6
Identities = 28/111 (25%), Positives = 39/111 (35%), Gaps = 12/111 (10%)
Query: 63 AESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPP---------PPPAAPP 113
A SS ++ +S Q Q ++A A + PP P PA PP
Sbjct: 862 AASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPP 921
Query: 114 AASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQ 164
A Q P P+ Q +S GG G++ Q P T G +
Sbjct: 922 TAPQQGLPGLSPAGPELGAFSQS---PASQMGGRAGLHCTQAYPVRTAGQE 969
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 142 bits (358), Expect = 2e-33
Identities = 188/614 (30%), Positives = 231/614 (37%), Gaps = 121/614 (19%)
Query: 374 QGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQS-QAQPQTGSGASRALPSWQEVSH 432
Q G+ L PS G F N AL + P + Q Q Q Q Q +
Sbjct: 3684 QHSGGAGSLAGPSGG--FFPGNLALRSLGPDSRLLQERQLQLQQ-----------QRMQL 3730
Query: 433 AQQLKQIAANRQQHARMQQH-------QQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSF 485
AQ+L+Q +QQ + QQH QQQ Q + GP P + + PS
Sbjct: 3731 AQKLQQ----QQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP-----QGLMPPSS 3781
Query: 486 GQQTFSPQSSPMP--GVAGGSGQSKVMANYMYKAGP-SAQGGHLDVLMQQKPQDLSRSFI 542
Q Q SP P G G G ++V G QG H VLM Q S
Sbjct: 3782 HQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLA 3841
Query: 543 NNPHPAMEPR---------------QGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYT 587
M R QG+ L H + L +Q SL
Sbjct: 3842 QQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQ 3901
Query: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
QQQQ QQQQQ QQQQQQQ QQQQQ QQQQ QQQQ QQQQQQQ QQQQQQ QQ
Sbjct: 3902 QQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQ----LQQQQQQLQQ 3957
Query: 648 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQV 707
QQQQQQQQ QQQQQQQQ +++L S QQ Q Q G G
Sbjct: 3958 QQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQ--------------QQQQQQVALGPGMPA 4003
Query: 708 SQQQRQDQHSVVG---------QNT-GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK 757
Q +G QNT P+ S P+T G + + + +
Sbjct: 4004 KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLA-IGTTPESMATEP 4062
Query: 758 QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQY 817
++ + Q LL+Q Q PQ Q + +PP Q++ ++ TA
Sbjct: 4063 GEVKPSLSGDSQLLLVQPQ---------PQPQPSSLQLQPPLRLPGQQQQQVSLLHTA-- 4111
Query: 818 SGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQ 877
GG S L S +S S H PS+S Q M NL
Sbjct: 4112 -GGGSHGQLGSGS--------------SSEASSVPHLLAQPSVSLGDQPGSMTQNL---- 4152
Query: 878 PNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLR 937
G Q +R P Q N P+PP GP + G G + QLR
Sbjct: 4153 -------LGPQQPMLER-PMQ------NNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLR 4198
Query: 938 PNLTHSMASMPPQR 951
L +A P R
Sbjct: 4199 AQLQGVLAKNPQLR 4212
Score = 95.5 bits (236), Expect = 3e-19
Identities = 114/420 (27%), Positives = 162/420 (38%), Gaps = 57/420 (13%)
Query: 428 QEVSHAQQLKQIAANRQQHARM---------QQHQQQHQPTNWSALPSSAGPSPGPFGQE 478
Q+ +QL Q+ +++H + QQ QQQ Q + + PS P
Sbjct: 3570 QQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLT 3629
Query: 479 KIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHL--DVLMQQKPQD 536
K+P P P G AGG ++ M A P GG L QQ+ Q
Sbjct: 3630 KLPGQLLPGHGLQPPQGPPGGQAGG---LRLTPGGM--ALPGQPGGPFLNTALAQQQQQQ 3684
Query: 537 LSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQ 596
S + P+ G P N + S+ P LL Q Q QQQ+
Sbjct: 3685 HSGGAGSLAGPS-----GGFFP--------GNLALRSLGPDSR---LLQERQLQLQQQRM 3728
Query: 597 QQQQQQQQQQQQQQQQQQ-------QQQQQQQSSISAQQ----------QQQQQSSISAQ 639
Q Q+ QQQQQQQQQQQ QQQQQQ + Q + Q
Sbjct: 3729 QLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQ 3788
Query: 640 QQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQP 699
Q Q Q Q Q QQQ P + Q Q L+ L L QQ Q
Sbjct: 3789 QLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGL- 3847
Query: 700 IAGMGYQV---SQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGK 756
MG+++ QQQ+Q QH G G S + ++G +++Q QQL +
Sbjct: 3848 ---MGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMS-HSGQPKLSAQPMGSLQQLQQQ 3903
Query: 757 KQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQ 816
+Q Q+Q ++Q+QQ LQQQ +++ Q Q + + + Q++ + Q Q
Sbjct: 3904 QQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQ 3963
Score = 70.9 bits (172), Expect = 7e-12
Identities = 135/560 (24%), Positives = 205/560 (36%), Gaps = 92/560 (16%)
Query: 319 PPMSDLELENMINATIKQDDPFNI-DLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPS 377
P S EL+ M ++ + + P I DL + ++ + K + ++ P Q
Sbjct: 3226 PAASGDELDKMESSLVASELPLLIEDLLEHEKKELQK------KQQLSAQLQPAQQQQQQ 3279
Query: 378 GSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRA------LPSWQEVS 431
+ GPA +M+ L PS+ SQ Q G +R L Q +
Sbjct: 3280 QQQHSLLSAPGPAQAMS---LPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPA 3336
Query: 432 HAQQLK----QIAANRQQHARMQQH--------QQQHQPT----NWSALPSSAGPSPGPF 475
HA Q + + Q H QH QQ QP +P S P
Sbjct: 3337 HALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQL 3396
Query: 476 GQEKIPSPSFGQQT----FSPQSSPMP----GVAGGSGQSKVMANYMYKAGPSAQGGHLD 527
++ + SF T F+ + P + G KVMA P +
Sbjct: 3397 AMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVS 3456
Query: 528 VLMQQKPQDLSRSFINN-------PHPAMEPRQGNTKP-------------------LFH 561
+L Q+ S N+ A +P Q P LFH
Sbjct: 3457 LLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFH 3516
Query: 562 FNSDQANQQMPSVLPSQ---NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 618
+ Q Q VL Q ++ S +Q+ ++ ++ + ++ + +QQ +
Sbjct: 3517 --TQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKI 3574
Query: 619 QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQ-------PA 671
Q+Q ++QQ++ +++ A+ + +QQQQQQQQQQQQQQ PS P
Sbjct: 3575 QKQLD-QVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPG 3633
Query: 672 QSLPS---QPLLRSPLPLQQKLLL----QQMQNQPIAGMGYQVSQQQRQDQHS-VVGQNT 723
Q LP QP P L L + QP QQ+Q QHS G
Sbjct: 3634 QLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLA 3693
Query: 724 GPS----PSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQL-LLQQQML 778
GPS P + S + +Q L QQ M Q LQ+Q +Q+QQ LL Q +
Sbjct: 3694 GPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAI 3753
Query: 779 ADAEKIAPQDQINRHLSRPP 798
++ P Q N+ L P
Sbjct: 3754 QQQQQQGPGVQTNQALGPKP 3773
Score = 44.3 bits (103), Expect = 7e-04
Identities = 68/312 (21%), Positives = 101/312 (32%), Gaps = 46/312 (14%)
Query: 409 QSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPT----NWSAL 464
Q Q Q Q + Q+ QQ +Q+ Q + QQQ Q A
Sbjct: 3945 QQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAK 4004
Query: 465 PSSAGPSPGPFG--------QEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYK 516
P SPG G ++ P+ + S+ G + MA +
Sbjct: 4005 PLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGE 4064
Query: 517 AGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLP 576
PS G +L+Q +PQ S P + +Q L H ++ Q+ S
Sbjct: 4065 VKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSS 4124
Query: 577 SQN--------KPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQ------------- 615
S+ +PS+ Q Q QQ ++ Q Q
Sbjct: 4125 SEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQG 4184
Query: 616 -----------QQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQ 664
Q + Q + A+ Q + S QQQ Q Q+Q QQ Q +Q Q
Sbjct: 4185 LPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQ 4244
Query: 665 QPSSQ--PAQSL 674
+P +Q P Q L
Sbjct: 4245 EPGTQTSPLQGL 4256
Score = 43.1 bits (100), Expect = 0.002
Identities = 69/255 (27%), Positives = 96/255 (37%), Gaps = 30/255 (11%)
Query: 384 PPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANR 443
P + GP + +T P S ++ P T G A+ + E S A + ++ +
Sbjct: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEG-PSTHQGGPLAIGTTPE-SMATEPGEVKPSL 4069
Query: 444 QQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAG- 502
+++ Q Q QP PSS P + P QQ S + G G
Sbjct: 4070 SGDSQLLLVQPQPQPQ-----PSSLQLQP------PLRLPGQQQQQVSLLHTAGGGSHGQ 4118
Query: 503 -GSGQSKVMANYMYK-AGPSAQGGHLDVLMQQK---PQD--LSRSFINN-------PHPA 548
GSG S ++ + A PS G M Q PQ L R NN P P
Sbjct: 4119 LGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPV 4178
Query: 549 MEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQ 608
++ QG Q Q+ VL P L H + QQQQQ Q Q+Q QQ Q
Sbjct: 4179 LQSGQGLPGVGIMPTVGQLRAQLQGVLAKN--PQLRHLSPQQQQQLQALLMQRQLQQSQA 4236
Query: 609 QQQQQQQQQQQQQSS 623
+Q Q+ Q+S
Sbjct: 4237 VRQTPPYQEPGTQTS 4251
Score = 42.7 bits (99), Expect = 0.002
Identities = 156/732 (21%), Positives = 247/732 (33%), Gaps = 153/732 (20%)
Query: 105 PPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQ 164
P PP PP S A A PP +L +S+ G+G P TP Q
Sbjct: 2190 PTAPPTYPPYPSPTGAPAQPP------------MLGASSRPGAGQPGEFHTTPPGTPRHQ 2237
Query: 165 RNSALIALQG---SLKRKQVVNL---------SPANSKRPNGFVDNSFLDIKRIRVGENL 212
++ L+ SL V P S P G L++K+ +G +
Sbjct: 2238 PSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFG-ESRKALEVKKEELGASS 2296
Query: 213 -SAGQGGLQ-INNGQSQIMSGTLPMSQAPLRKTNTLPSHTH----SPGNGLFNMGLKEVK 266
S G L +++ S G L + + K P + SPG +GL+ +
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPG-----LGLRPQE 2351
Query: 267 KEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLEL 326
P + L+ S + + + + Y P P E L S+P
Sbjct: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLP------- 2404
Query: 327 ENMINATIKQDDPFN-IDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPP 385
DPF+ + QSQ S+ P P SP + S P RPP
Sbjct: 2405 ----------SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPP 2454
Query: 386 SAGPAFSMANSALSTSSPIPSVPQ------SQAQPQTGSGASRALPSWQEVSHAQQLKQI 439
S S A P P P+ S A G+G P+ A +L
Sbjct: 2455 SRPQ--SRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGG---FPAALPAGPAGEL--- 2506
Query: 440 AANRQQHARMQQHQQQHQPTNWSALPSSAG----PSPGPFGQEKIPSPSFGQQTFSPQSS 495
HA++ Q P N+ P + PSP F + + G+ + P
Sbjct: 2507 ------HAKVPSGQ----PPNFVRSPGTGAFVGTPSPMRFTFPQ----AVGEPSLKPPV- 2551
Query: 496 PMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFIN-NPHPA---MEP 551
P PG+ G N + GP+ KPQ + + N HP+ + P
Sbjct: 2552 PQPGLPPPHG-----INSHFGPGPTLG----------KPQSTNYTVATGNFHPSGSPLGP 2596
Query: 552 RQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQ 611
G+T + + + +P P + P L H Q+ ++++
Sbjct: 2597 SSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGS-- 2654
Query: 612 QQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQ------QQQQQQQQQQQQQ 665
S +A+ Q +S Q + ++Q+Q+Q+ +QQ Q+ +Q++
Sbjct: 2655 ----------SLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEK 2704
Query: 666 PSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVG----- 720
++ A P P P AG QD+ S+VG
Sbjct: 2705 ETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAG---------TQDKSSLVGLPPSK 2755
Query: 721 -----QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQ--------IMEQ 767
G PS + S P + S + ++QL+G Q ++ + +Q
Sbjct: 2756 LSGPILGPGSFPSDDRLSRPPPPA--TPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQ 2813
Query: 768 KQQLLLQQQMLA 779
+QQL QQQ A
Sbjct: 2814 QQQLWQQQQATA 2825
Score = 36.6 bits (83), Expect = 0.14
Identities = 178/882 (20%), Positives = 280/882 (31%), Gaps = 156/882 (17%)
Query: 371 GLTQGPSGSPQLRPPSAGPA-------FSMANSALSTSSPIPSVPQSQAQPQTGSGASRA 423
G T GP P +GP F + + AL+ P+ + S +
Sbjct: 3186 GATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGG-PAASGDELDKMESSLVASE 3244
Query: 424 LPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSP 483
LP E + K++ +Q A++Q QQQ Q +L S+ GP+
Sbjct: 3245 LPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPA------------ 3292
Query: 484 SFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFIN 543
Q P P +AG Q + + Q G LM +P +
Sbjct: 3293 ---QAMSLPHEGSSPSLAGSQQQLSL------GLAGARQPGLPQPLMPTQPPAHALQQRL 3343
Query: 544 NPHPAMEPRQGNTKPLFHFNS-----DQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQ 598
P AM QG+ H Q++Q + S P P + QQ QQQ
Sbjct: 3344 APSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLA 3403
Query: 599 QQQQQQQQQQQQQQQQ----------------QQQQQQQSSISAQQQQQQQSSISAQQQQ 642
+ + ++ Q S A +QQ S+ AQ+
Sbjct: 3404 NSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLS 3463
Query: 643 QQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLP--SQPLLRSPLPLQQKLLL---QQMQN 697
Q Q++ P SQP + P +Q ++ Q + L QQ+
Sbjct: 3464 GGPSSDLQNHVAAGSGQERSAGDP-SQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQ 3522
Query: 698 QPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQL--MG 755
+ + Q+ ++ + Q T + QQS + +QL +
Sbjct: 3523 MQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVR 3582
Query: 756 KKQTLQRQIM-------EQKQQLLLQQQMLADAEKIAPQDQINRHLSRPP----PDYKDQ 804
K+Q +M +Q+QQ QQQ A Q R L++ P P + Q
Sbjct: 3583 KQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQ 3642
Query: 805 -------------RRNVGNM-----------------QPTAQYSGGSSTISLNSNQALAN 834
R G M Q Q+SGG+ +++ S
Sbjct: 3643 PPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPG 3702
Query: 835 PVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQR 894
++ + L P+S LL L Q M + L Q + Q+ Q+
Sbjct: 3703 NLALRS-LGPDSRLLQER------QLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQ 3755
Query: 895 NPKQLLANQNNPMM-PRPPTLGPSNNNN---------------VATFGAGSVGNSQQLRP 938
+Q Q N + P+P L P +++ G V QQ P
Sbjct: 3756 QQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHP 3815
Query: 939 N------------LTHSMASMPP---QRTSNVMITSNTTAPNWASQE---------GTSK 974
+T S P Q+ +M TA Q+ G S
Sbjct: 3816 GALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSH 3875
Query: 975 QQEALTSAGVR-----FPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQL--TPAVQMR 1027
Q++L S + P G+ Q LQQ QQ Q+ + QL Q +
Sbjct: 3876 LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQ 3935
Query: 1028 PMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTG-LNQSRTGINQPPSLTPSN 1086
Q+ Q Q + L + Q Q Q G LNQSRT ++
Sbjct: 3936 QQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV 3995
Query: 1087 FPSPNQSSRAFQGTDHSSDLAFDFL--SQQNDNMGPALNSDA 1126
P ++ Q L L ++ + + PA++S+A
Sbjct: 3996 ALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEA 4037
Score = 36.2 bits (82), Expect = 0.19
Identities = 43/181 (23%), Positives = 66/181 (36%), Gaps = 27/181 (14%)
Query: 355 PSLPMEKIVIKSEYSP----GLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVP-- 408
P P+ ++++ SP T P + PPS G A+ L P P
Sbjct: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLL 1028
Query: 409 QSQAQPQTGSGASRALPSWQEVSHAQQL----KQIAANRQQHARMQQHQQQHQPTNWSAL 464
Q PQ S S+ P +S L K + + + + ++ +P +
Sbjct: 1029 QHSLVPQN-SPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALE 1087
Query: 465 PSSAGPSPGPFGQEKIPSPS----------FGQQTF------SPQSSPMPGVAGGSGQSK 508
PS+ P P P G P+PS G+ T +P S P PG GS S+
Sbjct: 1088 PSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASE 1147
Query: 509 V 509
+
Sbjct: 1148 L 1148
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 139 bits (350), Expect = 2e-32
Identities = 132/373 (35%), Positives = 168/373 (45%), Gaps = 76/373 (20%)
Query: 385 PSAGPAFSMANSALSTSSPIPSVPQSQAQ-PQTGSGASRALPSWQEVSHAQQLKQIAANR 443
P+ GP +P+ P P T +G PS + S +Q +Q A +
Sbjct: 1849 PAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQ-QQPAVPQ 1907
Query: 444 QQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKI----PSPSFGQQT---FSPQSSP 496
Q R Q Q Q G GQ + PS S+G QT ++P S
Sbjct: 1908 GQRLRQQLQQSQ-----------------GMLGQSSVHQMTPSSSYGLQTSQGYTPYVSH 1950
Query: 497 MPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVL---------MQQKPQDLSRSFINNPHP 547
+ G+ +G + M Y + P Q H +QQ+P +++ P
Sbjct: 1951 V-GLQQHTGPAGTMVPPSYSSQPY-QSTHPSTNPTLVDPTRHLQQRPS----GYVHQQAP 2004
Query: 548 AMEPRQGNTKPLFHFNSDQANQQMPSV-----LPSQNKPSLLHYT-----QQQQQQQQQQ 597
+T+ H Q QQ P + + +Q + + T QQQQQQQQQQ
Sbjct: 2005 TYGHGLTSTQRFSH----QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQ 2060
Query: 598 QQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQ 657
QQQQQQQQQQQQQQQQ +QQQQ I QQQQQQQ QQQQQQQQQQQQQQQQQQQ
Sbjct: 2061 QQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQ-----QQQQQQQQQQQQQQQQQQQ 2115
Query: 658 QQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHS 717
QQQQQQ Q+ P QP +S Q++ L Q Q Q A + Q+ QQ
Sbjct: 2116 HQQQQQQ-------QAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQL------ 2162
Query: 718 VVGQNTGPSPSPN 730
NT P PS N
Sbjct: 2163 ---SNTQPQPSTN 2172
Score = 101 bits (251), Expect = 5e-21
Identities = 105/341 (30%), Positives = 135/341 (39%), Gaps = 53/341 (15%)
Query: 357 LPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQA---- 412
LPM+K+ + Y L +G L P S + P+VPQ Q
Sbjct: 1863 LPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQ--------PAVPQGQRLRQQ 1914
Query: 413 --QPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQH-------------QQQHQ 457
Q Q G S S+ Q Q H +QQH Q +Q
Sbjct: 1915 LQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQ 1974
Query: 458 PTNWSALPSSAGPS----PGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANY 513
T+ S P+ P+ P G +P++G S Q + Q M +
Sbjct: 1975 STHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTL-----QQTPMIST 2029
Query: 514 MYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPS 573
M SAQG V RS P + +Q + Q QQ
Sbjct: 2030 MTPM--SAQGVQAGV----------RSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
Query: 574 VLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQ 633
+ Q + +L +QQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQ +A Q Q Q
Sbjct: 2078 HIRQQQQQQIL-----RQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
Query: 634 SSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSL 674
S Q+Q QQ QQQQQ +Q QQQ QP+ ++
Sbjct: 2133 SQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNI 2173
Score = 92.0 bits (227), Expect = 3e-18
Identities = 115/419 (27%), Positives = 160/419 (38%), Gaps = 45/419 (10%)
Query: 380 PQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQI 439
P+ P A P + ST S P ++ + G G R+ P V L
Sbjct: 1767 PKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTEDY-GMGPGRSGPYGVTVP-PDLLHHP 1824
Query: 440 AANRQQHARMQQHQ----QQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSS 495
H +Q Q+QP LP+ GP P+ ++P + P
Sbjct: 1825 NPGSITHLNYRQGSIGLYTQNQP-----LPAG-GPRVDPYRPVRLPMQKLPTRPTYPGVL 1878
Query: 496 P--MPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPA----M 549
P M GV G S + Y + QG L +QQ L +S ++ P+ +
Sbjct: 1879 PTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGL 1938
Query: 550 EPRQGNTKPLFHFNSDQ-------------ANQQMPSVLPSQNKPSLLHYTQQQQQQQQQ 596
+ QG T + H Q ++Q S PS N P+L+ T+ QQ+
Sbjct: 1939 QTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTN-PTLVDPTRHLQQRPSG 1997
Query: 597 QQQQQQQQQ-----QQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQ 651
QQ Q+ Q QQ S+++ Q Q+ + + +QQQQQ
Sbjct: 1998 YVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGV--RSTAILPEQQQQQ 2055
Query: 652 QQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQ 711
QQQQQQQQQQQQQQ Q Q Q + L QQ+ QQ Q Q Q QQQ
Sbjct: 2056 QQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQ----QQQQQQQQQ 2111
Query: 712 RQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQ 770
+Q QH Q P P P S P QQ+ QQ + LQ+Q+ + Q
Sbjct: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQR--QGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Score = 50.8 bits (120), Expect = 7e-06
Identities = 78/325 (24%), Positives = 103/325 (31%), Gaps = 72/325 (22%)
Query: 543 NNPHPAMEPRQGNTKPL-FHFNSDQANQQMPSVLP-----------SQNKPSLLHYTQQQ 590
N P PA PR +P+ P VLP S K S+ Y QQQ
Sbjct: 1845 NQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSV--YRQQQ 1902
Query: 591 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQ 650
Q Q+ +QQ QQ Q Q Q SS Q Q +S QQ
Sbjct: 1903 PAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGT 1962
Query: 651 QQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP--------------LPLQQKLLLQQMQ 696
Q Q PS+ P P++ L + P L Q+ Q +Q
Sbjct: 1963 MVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQ 2022
Query: 697 NQPI-------AGMGYQVS---------QQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSG 740
P+ + G Q QQQ+Q Q Q
Sbjct: 2023 QTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQ------------------ 2064
Query: 741 YMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLS----- 795
QQ QQ +Q Q+QI+ Q+QQ QQQ ++ Q Q +H
Sbjct: 2065 -QQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQ 2123
Query: 796 ----RPPPDYKDQRRNVGNMQPTAQ 816
+P P + Q + G Q Q
Sbjct: 2124 AAPPQPQPQSQPQFQRQGLQQTQQQ 2148
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 127 bits (318), Expect = 8e-29
Identities = 123/357 (34%), Positives = 151/357 (42%), Gaps = 45/357 (12%)
Query: 573 SVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQ----- 627
S Q + L QQQQQQQQ QQQQQ QQQQQQQQQQQ Q QQS++ Q
Sbjct: 145 STATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVV 204
Query: 628 --------QQQQQQSSISAQQQQQQQQQQQQQQ----------QQQQQQQQQQQQQPSSQ 669
QQQQQQ I Q QQQ QQQQQQ QQQQQQQQQQQQQ +
Sbjct: 205 QQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL 264
Query: 670 PAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSP 729
AQ QP ++ P P + L QQ+Q Q Q Q Q V QN P
Sbjct: 265 QAQPPIQQPPMQQPQPPPSQALPQQLQQMHHT----QHHQPPPQPQQPPVAQNQPSQLPP 320
Query: 730 NPCSNPNTGSGYMNSQQSLLNQQ----LMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIA 785
+ P Q L Q + Q + Q QQ Q A+ +A
Sbjct: 321 QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVA 380
Query: 786 PQDQINRH----LSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTI 841
P Q+++ LS P P + Q P G + NSN VS+
Sbjct: 381 PGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSN------VSSGPA 434
Query: 842 LTPNSSLLSTS-HGTRMPSLSTAVQNMGMYGNLPCNQP-NTYSVTS--GMNQLTQQR 894
+P+S L S S ++ P + QN + P N P N SV S G +Q +Q+
Sbjct: 435 PSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQ 491
Score = 95.1 bits (235), Expect = 3e-19
Identities = 118/413 (28%), Positives = 148/413 (35%), Gaps = 107/413 (25%)
Query: 372 LTQGPS-GSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGA-------SRA 423
LT GP+ G+ + P GP S+ + P Q P T A S A
Sbjct: 88 LTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTA 147
Query: 424 LPSWQ----EVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEK 479
P Q +V+ QQ +Q +QQ A +QQ QQQ Q
Sbjct: 148 TPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ---------------------- 185
Query: 480 IPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSR 539
QQ F Q S M Q + A + Q+ Q L +
Sbjct: 186 -------QQQFQAQQSAM--------QQQFQA------------------VVQQQQQLQQ 212
Query: 540 SFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQ 599
+ +Q + L H N Q QQ + + + L QQQQQQQQQQQQ
Sbjct: 213 ---------QQQQQQHLIKLHHQNQQQIQQQQQQL----QRIAQLQLQQQQQQQQQQQQQ 259
Query: 600 QQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQ 659
QQQ Q Q QQ QQ Q S + QQ QQ Q Q QQ Q Q Q
Sbjct: 260 QQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLP 319
Query: 660 QQQQQQPSSQPAQSLPSQPL--------LRSPLPLQQKLLLQQMQNQPIA---------- 701
Q Q QP AQ+LP Q L +R+P+ +QQ + Q+Q Q A
Sbjct: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379
Query: 702 GMGYQVSQQQ-------RQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQS 747
G QVSQ Q Q+ P P P+P P S NS S
Sbjct: 380 APGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP--QPGQPSSQPNSNVS 430
Score = 32.3 bits (72), Expect = 2.7
Identities = 33/142 (23%), Positives = 55/142 (38%), Gaps = 16/142 (11%)
Query: 969 QEGTSKQQEALTSAG-VRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAP----------- 1016
Q+ +QQ+AL + ++ P P+Q+L Q + +Q P
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQN 313
Query: 1017 -PNQLTPAVQMRPMNQMSQTLNGQ---TMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQS 1072
P+QL P Q +P+ +Q L GQ T PL+ + + P + Q T + +
Sbjct: 314 QPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTA 373
Query: 1073 RTGINQPPSLTPSNFPSPNQSS 1094
+ P + S P SS
Sbjct: 374 QAAQMVAPGVQVSQSSLPMLSS 395
Score = 31.2 bits (69), Expect = 6.0
Identities = 29/106 (27%), Positives = 40/106 (37%), Gaps = 3/106 (2%)
Query: 369 SPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTG-SGASRALPSW 427
+PG+ S P L PS G S P P Q +QP + S PS
Sbjct: 380 APGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSS 439
Query: 428 QEVSHAQQLKQ--IAANRQQHARMQQHQQQHQPTNWSALPSSAGPS 471
S + Q Q + A Q+ + + P N S++ S AG S
Sbjct: 440 FLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSS 485
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 117 bits (293), Expect = 6e-26
Identities = 117/345 (33%), Positives = 159/345 (46%), Gaps = 31/345 (8%)
Query: 472 PGPFGQEKIPSPSFGQQTFSPQ---SSPM-PGVAGGSGQSKVMANYMYKAGPSAQGGHLD 527
PGP S Q+ PQ SSP P V+ G S++ + P + L
Sbjct: 37 PGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAE----ETRPGQRELQLQ 92
Query: 528 VLMQQKP--QDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLH 585
L QQ Q + P P +E +Q + S ++ SV + KP L
Sbjct: 93 QLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQL 152
Query: 586 YTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQSSISAQQQ-----QQQQSSIS 637
QQQQ Q QQ Q+QQ+ QQQQ+Q Q QQ Q+QQ QQ + Q Q QQQQ +
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212
Query: 638 AQQQQQQQQQQQQQQQQQQQQQ-QQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQ--- 693
QQ QQQ+Q QQQQ QQQQ+Q QQQQQ Q L Q L + LQQ+LL Q
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQA 272
Query: 694 QMQNQPIAGMGYQVSQQQR----QDQHSVVGQNTGPSPSPNPCSNPNTGSGYM----NSQ 745
Q+Q Q + Q+ QQQ+ Q Q + Q P P M S+
Sbjct: 273 QLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSE 332
Query: 746 QSLLNQ-QLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQ 789
Q L Q Q + ++Q L+RQ +++ QL LQ+++ +++ Q Q
Sbjct: 333 QELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQ 377
Score = 107 bits (267), Expect = 7e-23
Identities = 92/278 (33%), Positives = 131/278 (47%), Gaps = 33/278 (11%)
Query: 550 EPRQGNTKPLFHFNSDQ--ANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQ 607
EP++ N+ P S A++ P Q + L QQ + QQQ Q +Q QQ Q
Sbjct: 56 EPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPH 115
Query: 608 QQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQ---------QQQQQQQQQQQQQQQQQQ 658
+ QQQ QQ QQQ S Q QQ++ S+ Q+ QQQQ Q QQ Q+QQ+ QQ
Sbjct: 116 LELQQQPQQDGQQQLS---QLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQ 172
Query: 659 QQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQ--MQNQPIAGMGYQVSQQQRQDQH 716
QQ+Q Q +Q Q L Q L+ + QQ L QQ +Q Q + Q+ QQQ Q Q
Sbjct: 173 QQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQ 232
Query: 717 SVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQT-LQRQIMEQKQQLLLQQ 775
+ Q + QQ L QQL+ ++Q LQ+Q++EQ QQ LQQ
Sbjct: 233 EQLQQQQ---------------QLLLLQQQGQLQQQLLQQQQAQLQQQLLEQ-QQAQLQQ 276
Query: 776 QMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQP 813
Q+L ++ Q Q + L + + Q+ ++P
Sbjct: 277 QLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEP 314
Score = 80.9 bits (198), Expect = 7e-15
Identities = 65/211 (30%), Positives = 96/211 (45%), Gaps = 38/211 (18%)
Query: 529 LMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQ 588
L+QQ+ + L + + ++ +Q F +Q QQ +L Q Q
Sbjct: 203 LLQQQQEQLQQQQLLQQQEQLQQQQ------FQQQQEQLQQQQQLLLLQQQGQLQQQLLQ 256
Query: 589 QQQQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQSSISAQQQQQQQSSI--------- 636
QQQ Q QQQ +QQQ Q QQQ QQQ+Q QQQQQQ + QQ+Q QQ +
Sbjct: 257 QQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEE 316
Query: 637 --------------SAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS 682
S Q+ +QQ+Q+ ++QQ+ ++QQ+Q+Q Q + Q L Q
Sbjct: 317 EEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQ----- 371
Query: 683 PLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQ 713
L QQ+ L QQ + + QQ+ Q
Sbjct: 372 -LEQQQQQLEQQEVQLELTPVELGAQQQEVQ 401
Score = 66.6 bits (161), Expect = 1e-10
Identities = 69/294 (23%), Positives = 117/294 (39%), Gaps = 33/294 (11%)
Query: 425 PSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPS 484
P Q + QQL+ QQ + QQ Q Q Q + QE++
Sbjct: 148 PELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQ---------QEQLQQQV 198
Query: 485 FGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINN 544
QQ Q + Q ++ + Q +L+QQ+ Q L + +
Sbjct: 199 QEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQ-LQQQLLQQ 257
Query: 545 PHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQ 604
++ + L Q QQ+ Q + QQQQ+Q QQQQ Q
Sbjct: 258 QQAQLQQQ------LLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPP 311
Query: 605 QQQQQQQQ-----------QQQQQQQQQSSISAQQQ---QQQQSSISAQQQQQQQQQQQQ 650
+ +++++ +Q+ +QQ+ + QQ+ QQ+Q + + Q++ QQ +QQ
Sbjct: 312 LEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQ 371
Query: 651 QQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMG 704
+QQQQQ +QQ+ Q + Q + P+Q +L Q++ P AG G
Sbjct: 372 LEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPEL---QLELVPAAGGG 422
Score = 60.8 bits (146), Expect = 7e-09
Identities = 88/404 (21%), Positives = 148/404 (36%), Gaps = 54/404 (13%)
Query: 281 GQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPF 340
G +QE P P + + +E+ + P +L+L+ + Q P
Sbjct: 48 GSESQEEEEPQERNSSPQRPAVSAPVGA--SEIAEETRPGQRELQLQQLEQQPEPQQQP- 104
Query: 341 NIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALST 400
Q Q P+P L +++ G QL S+ + L
Sbjct: 105 -----QHEQLQQPQPHLELQQ-----------QPQQDGQQQLSQLQQEKHQSVHHQELKP 148
Query: 401 SSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQ-------HQ 453
+ Q Q QPQ R L QE QQ ++ +QQ QQ Q
Sbjct: 149 ELQLMH-QQQQLQPQQVQEQQR-LQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQ 206
Query: 454 QQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANY 513
QQ Q L QE++ F QQ Q + GQ +
Sbjct: 207 QQEQLQQQQLLQQ----------QEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQ 256
Query: 514 MYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQM-- 571
+A Q L++Q+ L + + ++ +Q + L +Q QQ
Sbjct: 257 QQQAQLQQQ------LLEQQQAQLQQQLLLQQQEQLQQQQ--QQQLLQQQQEQLQQQQLQ 308
Query: 572 -PSVLPSQNKPSLLHYT-----QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSIS 625
P + P + + L +Q+ +QQ+Q+ ++QQ+ ++QQ+Q+Q Q + Q++
Sbjct: 309 PPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQL 368
Query: 626 AQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQ 669
QQ +QQQ + Q+ Q + + QQQ+ Q + QP Q
Sbjct: 369 EQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQ 412
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 114 bits (285), Expect = 5e-25
Identities = 93/245 (37%), Positives = 107/245 (43%), Gaps = 31/245 (12%)
Query: 573 SVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQ----- 627
S Q + L QQQQQQQQ QQQQQ QQQQQQQQQQQ Q QQS++ Q
Sbjct: 145 STATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVV 204
Query: 628 --------QQQQQQSSISAQQQQQQQQQQQQQQ----------QQQQQQQQQQQQQPSSQ 669
QQQQQQ I Q QQQ QQQQQQ QQQQQQQQQQQQQ +
Sbjct: 205 QQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL 264
Query: 670 PAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSP 729
AQ QP ++ P P + L QQ+Q Q Q Q Q V QN P
Sbjct: 265 QAQPPIQQPPMQQPQPPPSQALPQQLQQMHHT----QHHQPPPQPQQPPVAQNQPSQLPP 320
Query: 730 NPCSNPNTGSGYMNSQQSLLNQQ----LMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIA 785
+ P Q L Q + Q + Q QQ Q A+ +A
Sbjct: 321 QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVA 380
Query: 786 PQDQI 790
P Q+
Sbjct: 381 PGVQM 385
Score = 98.6 bits (244), Expect = 3e-20
Identities = 129/494 (26%), Positives = 171/494 (34%), Gaps = 109/494 (22%)
Query: 372 LTQGPS-GSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGA-------SRA 423
LT GP+ G+ + P GP S+ + P Q P T A S A
Sbjct: 88 LTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTA 147
Query: 424 LPSWQ----EVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEK 479
P Q +V+ QQ +Q +QQ A +QQ QQQ Q
Sbjct: 148 TPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ---------------------- 185
Query: 480 IPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSR 539
QQ F Q S M Q + A + Q+ Q L +
Sbjct: 186 -------QQQFQAQQSAM--------QQQFQA------------------VVQQQQQLQQ 212
Query: 540 SFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQ 599
+ +Q + L H N Q QQ + + + L QQQQQQQQQQQQ
Sbjct: 213 ---------QQQQQQHLIKLHHQNQQQIQQQQQQL----QRIAQLQLQQQQQQQQQQQQQ 259
Query: 600 QQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQ 659
QQQ Q Q QQ QQ Q S + QQ QQ Q Q QQ Q Q Q
Sbjct: 260 QQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLP 319
Query: 660 QQQQQQPSSQPAQSLPSQPL--------LRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQ 711
Q Q QP AQ+LP Q L +R+P+ +QQ + Q+Q Q A Q +Q
Sbjct: 320 PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV 379
Query: 712 RQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQL 771
+ P T + S L +Q M +
Sbjct: 380 APGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQ--------------- 424
Query: 772 LLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGG-----SSTISL 826
+ Q L +P Q+ S PPP + + QP + S G SS +
Sbjct: 425 -VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 483
Query: 827 NSNQALANPVSTHT 840
S Q +PV+ T
Sbjct: 484 PSPQPSQSPVTART 497
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 113 bits (283), Expect = 9e-25
Identities = 82/184 (44%), Positives = 99/184 (53%), Gaps = 21/184 (11%)
Query: 584 LHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQ 643
LH QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQ A++QQQ
Sbjct: 146 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQQQQQHPGKQAKEQQQ 202
Query: 644 QQQQQQQ--------QQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ-------Q 688
QQQQQQQ QQQ Q QQ QQQQ S Q L S P ++ LP+Q
Sbjct: 203 QQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 262
Query: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPN--PCSNPNTGSGYMNSQQ 746
+QQ+ + + G+ + + N+ + S N S P T +N Q
Sbjct: 263 PAEIQQLWKE-VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQS 321
Query: 747 SLLN 750
S+L+
Sbjct: 322 SVLS 325
Score = 107 bits (266), Expect = 9e-23
Identities = 100/335 (29%), Positives = 144/335 (42%), Gaps = 55/335 (16%)
Query: 572 PSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQQQQQQSSISAQQQ 629
P V+ Q +L QQ Q QQQQ QQQQ Q+ ++QQ+Q + QQQ
Sbjct: 96 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155
Query: 630 QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQK 689
QQQQ QQQQQQQQQQQQQQQQQQQQQQQQQQQ + A+ Q + L QQ
Sbjct: 156 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215
Query: 690 LLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLL 749
+ QQ+ QQ +Q QH + Q G P Q+ L
Sbjct: 216 VFQQQLLQM----------QQLQQQQHLLSLQRQGLISIP--------------PGQAAL 251
Query: 750 NQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVG 809
Q + + +I + +++ M +D +H G
Sbjct: 252 PVQSLPQAGLSPAEIQQLWKEVTGVHSM---------EDNGIKH---------------G 287
Query: 810 NMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGM 869
+ T S SST S N+++A + P++ H+I+ SS+LS + + A +
Sbjct: 288 GLDLTTNNS--SSTTSSNTSKA-SPPITHHSIVNGQSSVLSARRDSSSHEETGASHT--L 342
Query: 870 YGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQN 904
YG+ C P S+ Q + N + L +++
Sbjct: 343 YGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRS 377
Score = 52.4 bits (124), Expect = 2e-06
Identities = 115/549 (20%), Positives = 194/549 (35%), Gaps = 65/549 (11%)
Query: 392 SMANSALSTSSPIPSVPQSQAQPQTG--SGASRALPSWQEVSHAQQLKQIAANRQQHARM 449
+++NS+++ + Q A + G SG + + S E+ H QQ + + A RQ +
Sbjct: 9 TISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQ 68
Query: 450 QQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQS-SPMPGVAGGSGQSK 508
Q + ++ P S + I +P QQ Q SP A Q
Sbjct: 69 QTSGLKSPKSSDKQRPLQVPVSVAMMTPQVI-TPQQMQQILQQQVLSPQQLQALLQQQQA 127
Query: 509 VMANYM-----YKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFN 563
VM YK + HL +L QQ+ Q + + +Q
Sbjct: 128 VMLQQQQLQEFYKK--QQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ---------- 175
Query: 564 SDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQ 620
Q QQ Q P ++QQQQQQQQQQ QQ QQQ Q QQ QQQQ
Sbjct: 176 QQQQQQQQQQQQQQQQHPGK---QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQH 232
Query: 621 QSSISAQ-------------QQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPS 667
S+ Q Q Q+ +S + QQ ++ + + +
Sbjct: 233 LLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLT 292
Query: 668 SQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSP 727
+ + S S ++ P+ ++ Q+ ++ S ++ H++ G P
Sbjct: 293 TNNSSSTTSSNTSKASPPITHHSIVNG-QSSVLSARRDSSSHEETGASHTLYGHGVCKWP 351
Query: 728 SPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQ 787
C + G + L N+ + + T Q ++ Q Q L+ Q+ + E++
Sbjct: 352 G---CESICEDFGQF--LKHLNNEHALDDRSTAQCRVQMQVVQ-QLEIQLSKERERL--- 402
Query: 788 DQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILT---- 843
+ HL P + K + + + T + Q P + T +T
Sbjct: 403 QAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPS 462
Query: 844 -------PNSSLLSTSHGTR--MPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQR 894
PN + H + +P S N Y N P TY+ + Q +
Sbjct: 463 VITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATL--IRQAIMES 520
Query: 895 NPKQLLANQ 903
+ +QL N+
Sbjct: 521 SDRQLTLNE 529
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 113 bits (283), Expect = 9e-25
Identities = 82/184 (44%), Positives = 99/184 (53%), Gaps = 21/184 (11%)
Query: 584 LHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQ 643
LH QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQ A++QQQ
Sbjct: 54 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQQQQQHPGKQAKEQQQ 110
Query: 644 QQQQQQQ--------QQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ-------Q 688
QQQQQQQ QQQ Q QQ QQQQ S Q L S P ++ LP+Q
Sbjct: 111 QQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 170
Query: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPN--PCSNPNTGSGYMNSQQ 746
+QQ+ + + G+ + + N+ + S N S P T +N Q
Sbjct: 171 PAEIQQLWKE-VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQS 229
Query: 747 SLLN 750
S+L+
Sbjct: 230 SVLS 233
Score = 107 bits (266), Expect = 9e-23
Identities = 100/335 (29%), Positives = 144/335 (42%), Gaps = 55/335 (16%)
Query: 572 PSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQQQQQQSSISAQQQ 629
P V+ Q +L QQ Q QQQQ QQQQ Q+ ++QQ+Q + QQQ
Sbjct: 4 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 63
Query: 630 QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQK 689
QQQQ QQQQQQQQQQQQQQQQQQQQQQQQQQQ + A+ Q + L QQ
Sbjct: 64 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123
Query: 690 LLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLL 749
+ QQ+ QQ +Q QH + Q G P Q+ L
Sbjct: 124 VFQQQLLQM----------QQLQQQQHLLSLQRQGLISIP--------------PGQAAL 159
Query: 750 NQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVG 809
Q + + +I + +++ M +D +H G
Sbjct: 160 PVQSLPQAGLSPAEIQQLWKEVTGVHSM---------EDNGIKH---------------G 195
Query: 810 NMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGM 869
+ T S SST S N+++A + P++ H+I+ SS+LS + + A +
Sbjct: 196 GLDLTTNNS--SSTTSSNTSKA-SPPITHHSIVNGQSSVLSARRDSSSHEETGASHT--L 250
Query: 870 YGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQN 904
YG+ C P S+ Q + N + L +++
Sbjct: 251 YGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRS 285
Score = 106 bits (265), Expect = 1e-22
Identities = 70/130 (53%), Positives = 81/130 (62%), Gaps = 13/130 (10%)
Query: 569 QQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQ 628
QQ +V+ Q + + QQ+Q Q QQQQQQQQQQQQQQQQQQQQQQQQ QQ
Sbjct: 31 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ-----QQ 85
Query: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ 688
QQQQQ QQQQQQQQQ +Q ++QQQQQQQQQQ + AQ L Q L LQQ
Sbjct: 86 QQQQQ-----QQQQQQQQQHPGKQAKEQQQQQQQQQQLA---AQQLVFQQQLLQMQQLQQ 137
Query: 689 KLLLQQMQNQ 698
+ L +Q Q
Sbjct: 138 QQHLLSLQRQ 147
Score = 104 bits (260), Expect = 4e-22
Identities = 72/139 (51%), Positives = 82/139 (58%), Gaps = 19/139 (13%)
Query: 569 QQMPSVLPSQ--NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQ------QQQQQQQQQQ 620
QQM +L Q + L QQQQ QQQQ Q+ ++QQ+Q QQQQQQQQQQ
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69
Query: 621 QSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLL 680
Q QQQQQQQ QQQQQQQQQQQQQQQQQQQQQQ +Q Q Q Q L
Sbjct: 70 Q-----QQQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA 119
Query: 681 RSPLPLQQKLL-LQQMQNQ 698
L QQ+LL +QQ+Q Q
Sbjct: 120 AQQLVFQQQLLQMQQLQQQ 138
Score = 50.8 bits (120), Expect = 7e-06
Identities = 84/408 (20%), Positives = 143/408 (35%), Gaps = 54/408 (13%)
Query: 525 HLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLL 584
HL +L QQ+ Q + + +Q Q QQ Q P
Sbjct: 55 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQ----------QQQQQQQQQQQQQQQQHPGK- 103
Query: 585 HYTQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQSSISAQ-------------Q 628
++QQQQQQQQQQ QQ QQQ Q QQ QQQQ S+ Q
Sbjct: 104 --QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPV 161
Query: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ 688
Q Q+ +S + QQ ++ + + ++ + S S ++ P+
Sbjct: 162 QSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITH 221
Query: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSL 748
++ Q+ ++ S ++ H++ G P C + G + L
Sbjct: 222 HSIVNG-QSSVLSARRDSSSHEETGASHTLYGHGVCKWPG---CESICEDFGQF--LKHL 275
Query: 749 LNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNV 808
N+ + + T Q ++ Q Q L+ Q+ + E++ + HL P + K + +
Sbjct: 276 NNEHALDDRSTAQCRVQMQVVQ-QLEIQLSKERERL---QAMMTHLHMRPSEPKPSPKPL 331
Query: 809 GNMQPTAQYSGGSSTISLNSNQALANPVSTHTILT-----------PNSSLLSTSHGTR- 856
+ T + Q P + T +T PN + H +
Sbjct: 332 NLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKY 391
Query: 857 -MPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQ 903
+P S N Y N P TY+ + Q + + +QL N+
Sbjct: 392 NIPMSSEIAPNYEFYKNADVRPPFTYATL--IRQAIMESSDRQLTLNE 437
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 113 bits (283), Expect = 9e-25
Identities = 82/184 (44%), Positives = 99/184 (53%), Gaps = 21/184 (11%)
Query: 584 LHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQ 643
LH QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQ A++QQQ
Sbjct: 171 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQQQQQHPGKQAKEQQQ 227
Query: 644 QQQQQQQ--------QQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ-------Q 688
QQQQQQQ QQQ Q QQ QQQQ S Q L S P ++ LP+Q
Sbjct: 228 QQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 287
Query: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPN--PCSNPNTGSGYMNSQQ 746
+QQ+ + + G+ + + N+ + S N S P T +N Q
Sbjct: 288 PAEIQQLWKE-VTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQS 346
Query: 747 SLLN 750
S+L+
Sbjct: 347 SVLS 350
Score = 107 bits (266), Expect = 9e-23
Identities = 100/335 (29%), Positives = 144/335 (42%), Gaps = 55/335 (16%)
Query: 572 PSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQ--QQQQQQQQSSISAQQQ 629
P V+ Q +L QQ Q QQQQ QQQQ Q+ ++QQ+Q + QQQ
Sbjct: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
Query: 630 QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQK 689
QQQQ QQQQQQQQQQQQQQQQQQQQQQQQQQQ + A+ Q + L QQ
Sbjct: 181 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
Query: 690 LLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLL 749
+ QQ+ QQ +Q QH + Q G P Q+ L
Sbjct: 241 VFQQQLLQM----------QQLQQQQHLLSLQRQGLISIP--------------PGQAAL 276
Query: 750 NQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVG 809
Q + + +I + +++ M +D +H G
Sbjct: 277 PVQSLPQAGLSPAEIQQLWKEVTGVHSM---------EDNGIKH---------------G 312
Query: 810 NMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGM 869
+ T S SST S N+++A + P++ H+I+ SS+LS + + A +
Sbjct: 313 GLDLTTNNS--SSTTSSNTSKA-SPPITHHSIVNGQSSVLSARRDSSSHEETGASHT--L 367
Query: 870 YGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQN 904
YG+ C P S+ Q + N + L +++
Sbjct: 368 YGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRS 402
Score = 106 bits (265), Expect = 1e-22
Identities = 70/130 (53%), Positives = 81/130 (62%), Gaps = 13/130 (10%)
Query: 569 QQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQ 628
QQ +V+ Q + + QQ+Q Q QQQQQQQQQQQQQQQQQQQQQQQQ QQ
Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ-----QQ 202
Query: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ 688
QQQQQ QQQQQQQQQ +Q ++QQQQQQQQQQ + AQ L Q L LQQ
Sbjct: 203 QQQQQ-----QQQQQQQQQHPGKQAKEQQQQQQQQQQLA---AQQLVFQQQLLQMQQLQQ 254
Query: 689 KLLLQQMQNQ 698
+ L +Q Q
Sbjct: 255 QQHLLSLQRQ 264
Score = 104 bits (260), Expect = 4e-22
Identities = 72/139 (51%), Positives = 82/139 (58%), Gaps = 19/139 (13%)
Query: 569 QQMPSVLPSQ--NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQ------QQQQQQQQQQ 620
QQM +L Q + L QQQQ QQQQ Q+ ++QQ+Q QQQQQQQQQQ
Sbjct: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
Query: 621 QSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLL 680
Q QQQQQQQ QQQQQQQQQQQQQQQQQQQQQQ +Q Q Q Q L
Sbjct: 187 Q-----QQQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLA 236
Query: 681 RSPLPLQQKLL-LQQMQNQ 698
L QQ+LL +QQ+Q Q
Sbjct: 237 AQQLVFQQQLLQMQQLQQQ 255
Score = 50.8 bits (120), Expect = 7e-06
Identities = 84/408 (20%), Positives = 143/408 (35%), Gaps = 54/408 (13%)
Query: 525 HLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLL 584
HL +L QQ+ Q + + +Q Q QQ Q P
Sbjct: 172 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQ----------QQQQQQQQQQQQQQQQHPGK- 220
Query: 585 HYTQQQQQQQQQQQQQQQQQQ---QQQQQQQQQQQQQQQQSSISAQ-------------Q 628
++QQQQQQQQQQ QQ QQQ Q QQ QQQQ S+ Q
Sbjct: 221 --QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPV 278
Query: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ 688
Q Q+ +S + QQ ++ + + ++ + S S ++ P+
Sbjct: 279 QSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITH 338
Query: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSL 748
++ Q+ ++ S ++ H++ G P C + G + L
Sbjct: 339 HSIVNG-QSSVLSARRDSSSHEETGASHTLYGHGVCKWPG---CESICEDFGQF--LKHL 392
Query: 749 LNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNV 808
N+ + + T Q ++ Q Q L+ Q+ + E++ + HL P + K + +
Sbjct: 393 NNEHALDDRSTAQCRVQMQVVQ-QLEIQLSKERERL---QAMMTHLHMRPSEPKPSPKPL 448
Query: 809 GNMQPTAQYSGGSSTISLNSNQALANPVSTHTILT-----------PNSSLLSTSHGTR- 856
+ T + Q P + T +T PN + H +
Sbjct: 449 NLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKY 508
Query: 857 -MPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQ 903
+P S N Y N P TY+ + Q + + +QL N+
Sbjct: 509 NIPMSSEIAPNYEFYKNADVRPPFTYATL--IRQAIMESSDRQLTLNE 554
Score = 33.9 bits (76), Expect = 0.92
Identities = 44/213 (20%), Positives = 78/213 (36%), Gaps = 18/213 (8%)
Query: 604 QQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663
Q+ + Q S++S+Q + S+ + + QQQQ Q +
Sbjct: 3 QESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAAR 62
Query: 664 QQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNT 723
Q Q L S PLQ+ L ++ + D H NT
Sbjct: 63 QLLLQQQTSGLKSPKSSDKQRPLQELLPETKL----------CICGHSSGDGHP---HNT 109
Query: 724 GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEK 783
P P + Q +L QQ++ +Q + +++Q+Q ++LQQQ L + K
Sbjct: 110 FAVPVSVAMMTPQVIT--PQQMQQILQQQVLSPQQL--QALLQQQQAVMLQQQQLQEFYK 165
Query: 784 IAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQ 816
Q+Q++ L + + Q++ Q Q
Sbjct: 166 -KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQ 197
>gi|120952764 mastermind-like domain containing 1 [Homo sapiens]
Length = 774
Score = 107 bits (268), Expect = 5e-23
Identities = 122/487 (25%), Positives = 186/487 (38%), Gaps = 72/487 (14%)
Query: 302 MDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPM-- 359
+D ELQEL ELT I P ++L+LE ++ K ++P +D Q + +TP+PS+ M
Sbjct: 172 VDQELQELLEELTKIQDPSPNELDLEKILGT--KPEEPLVLDHPQATLSTTPKPSVQMSH 229
Query: 360 -EKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGS 418
E + E++ +Q S Q+ S G ++S+ +++ SP S+ QS++Q Q
Sbjct: 230 LESLASSKEFASSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAML 289
Query: 419 GAS---RALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSA------- 468
+ +P W HA QLK +AA++Q A +QQ +WS LP
Sbjct: 290 PVALPPLPVPQWH---HAHQLKALAASKQGSAT----KQQGPTPSWSGLPPPGLSPPYRP 342
Query: 469 --GPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVM---ANYMYKAGPSAQG 523
P P P P P FSPQS + ++ + + N + + S+
Sbjct: 343 VPSPHPPPLPLPPPPPP------FSPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSN 396
Query: 524 GHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSL 583
L M P+ L + P P+ L + S LP+ N
Sbjct: 397 AALGPAMPYAPEKLPSPALTQ-QPQFGPQSSILANLMSSTIKTPQGHLMSALPASNPGPS 455
Query: 584 LHYTQQQQQQQQQQQQQQQQQ--------------QQQQQQQQQQQQQQQQQSSISA--- 626
Y ++ QQ Q QQQQQQQQQQQ IS+
Sbjct: 456 PPYRPEKLSSPGLPQQSFTPQCSLIRSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSS 515
Query: 627 ------QQQQQQQSSISAQQ---------------QQQQQQQQQQQQQQQQQQQQQQQQQ 665
QQ SS A + + Q+ +Q QQ
Sbjct: 516 KTLSMIMQQGMASSSPGATEPFTFGNTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQ 575
Query: 666 PSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGP 725
P+ A S + + L LQQ+ QQ Q + + Q+ QQ ++ Q SV +
Sbjct: 576 PTPTQASSATASSTATATLQLQQQQQQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPA 635
Query: 726 SPSPNPC 732
P C
Sbjct: 636 LPRQGCC 642
Score = 38.1 bits (87), Expect = 0.049
Identities = 101/464 (21%), Positives = 160/464 (34%), Gaps = 80/464 (17%)
Query: 86 ARKAGKHTKATATAATTTAPPPPPAAPP----AASQAAATAAPPPPPDYHHHHQQHLLNS 141
A K G TK + + PPP +PP + PPPPP + S
Sbjct: 312 ASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPFSPQSLMVSCMS 371
Query: 142 SNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFL 201
SN + G S+ N+AL K SPA +++P +S L
Sbjct: 372 SNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLP---SPALTQQPQFGPQSSIL 428
Query: 202 DIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMG 261
NL + I Q +MS LP S N PS + P L + G
Sbjct: 429 --------ANLMSS----TIKTPQGHLMS-ALPAS-------NPGPSPPYRP-EKLSSPG 467
Query: 262 LKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPM 321
L + P CS T N +Q + +F +++ S +
Sbjct: 468 LPQQSFTP----QCSLIRSLTPTS-----NLLSQQQQQQQQQQQANVIFKPISSNSSKTL 518
Query: 322 SDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQ 381
S + + M +++ +PF + P E K P ++ PS
Sbjct: 519 SMIMQQGMASSSPGATEPFTFG------NTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHY 572
Query: 382 LRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAA 441
L+ P+ P + + +A ST++ + Q Q Q Q S L Q + Q+ ++ A
Sbjct: 573 LQQPT--PTQASSATASSTATATLQLQQQQQQQQQQPDHSSFLLQ-QMMQQPQRFQRSVA 629
Query: 442 NRQQHARMQQH--------------QQQHQPTNWSALPSSAGPSPG-------------- 473
+ A +Q + QHQ N + S P PG
Sbjct: 630 SDSMPALPRQGCCHLFAWTSAASSVKPQHQHGN--SFTSRQDPQPGDVSPSNITHVDKAC 687
Query: 474 PFGQEKIPSPSFGQQTFSPQS----SPMPGVAGGSGQSKVMANY 513
G+ + P S G+Q S Q+ S +PG + ++V ++Y
Sbjct: 688 KLGEARHPQVSLGRQPPSCQALGSESFLPGSSFAHELARVTSSY 731
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 98.6 bits (244), Expect = 3e-20
Identities = 86/248 (34%), Positives = 106/248 (42%), Gaps = 29/248 (11%)
Query: 563 NSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQS 622
+S Q + +VL SQ K + T QQQQQ QQQQQQ Q QQ Q QQQQQ
Sbjct: 376 HSQQGHTNANAVLFSQVK--VTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQ 433
Query: 623 SISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS 682
IS Q QQ +QQQQQQQQ Q QQQ Q QQQ P Q + P Q L
Sbjct: 434 QISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHR--PQQQL--- 488
Query: 683 PLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYM 742
P QQ+ LQQ +Q Q Q Q QHS++ Q
Sbjct: 489 -QPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQ--------------------- 526
Query: 743 NSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYK 802
QQ + QQL Q Q+Q M+ + L Q A ++ PQ + + PP
Sbjct: 527 QQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSP 586
Query: 803 DQRRNVGN 810
Q + G+
Sbjct: 587 QQHQLFGH 594
Score = 93.6 bits (231), Expect = 1e-18
Identities = 70/180 (38%), Positives = 85/180 (47%), Gaps = 16/180 (8%)
Query: 529 LMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQ 588
L QQ+ Q +S+ P+P P + Q QQ P Q L + Q
Sbjct: 427 LQQQQQQQISQQ----PYPQQPPHPFS----------QQQQQQQQAHPHQFSQQQLQFPQ 472
Query: 589 QQQQQQQQQQQQQQQQQQQQQQQQQQQQ-QQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
QQ QQ + QQQ Q QQQ QQQ Q QQ + QQ Q Q S QQQQQQQ
Sbjct: 473 QQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQI 532
Query: 648 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQV 707
QQQQ Q+ QQQQQQQ Q + P S SQ L+ +P QQ QQ Q P + +Q+
Sbjct: 533 QQQQLQRMHQQQQQQQMQSQTAPHLSQTSQ-ALQHQVPPQQPPQQQQQQQPPPSPQQHQL 591
Score = 82.4 bits (202), Expect = 2e-15
Identities = 79/269 (29%), Positives = 98/269 (36%), Gaps = 52/269 (19%)
Query: 428 QEVSHAQQ---------LKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQE 478
Q+V+H+QQ Q+ + H QQ Q Q Q L Q+
Sbjct: 372 QQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQP--------QQ 423
Query: 479 KIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLS 538
+ QQ S Q P S Q + Q P S
Sbjct: 424 IMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQ-------------------QQAHPHQFS 464
Query: 539 RSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQ 598
+ + P + P Q Q ++ + P Q + +L Q QQ Q QQQ
Sbjct: 465 QQQLQFPQQQLHPPQ------------QLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQ 512
Query: 599 QQQQQQQQ----QQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQ 654
Q Q QQQ QQQQQQQ QQQQ Q+ QQQQ Q + Q Q Q Q QQ
Sbjct: 513 QLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQ 572
Query: 655 QQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
QQQQQQQ PS Q Q P + P
Sbjct: 573 PPQQQQQQQPPPSPQQHQLFGHDPAVEIP 601
Score = 62.8 bits (151), Expect = 2e-09
Identities = 73/258 (28%), Positives = 99/258 (38%), Gaps = 33/258 (12%)
Query: 575 LPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQS 634
+ N+PS + + Q + +QQ QQ Q + + QQQQ
Sbjct: 347 IQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQ 406
Query: 635 SISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQ 694
+ QQQ Q QQ Q QQQQQQQ Q Q P QP P P Q+ QQ
Sbjct: 407 AQQQQQQHPVLHLQPQQIMQLQQQQQQQISQ------QPYPQQP----PHPFSQQ---QQ 453
Query: 695 MQNQPIAGMGYQVSQQQ---RQDQHSVVGQNTGPSPSPNPCSNPNT-GSGYMNSQQSLLN 750
Q Q +Q SQQQ Q Q Q P P + + QQ L
Sbjct: 454 QQQQ---AHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQ 510
Query: 751 QQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINR----HLSRP--------P 798
QQ + + Q Q +++Q+QQ +QQQ L + Q Q+ HLS+ P
Sbjct: 511 QQQLAQLQQ-QHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVP 569
Query: 799 PDYKDQRRNVGNMQPTAQ 816
P Q++ P+ Q
Sbjct: 570 PQQPPQQQQQQQPPPSPQ 587
Score = 35.0 bits (79), Expect = 0.41
Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 1/101 (0%)
Query: 974 KQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVA-PPNQLTPAVQMRPMNQM 1032
+QQ+ + +P P ++ Q QQ QFSQ+ + P QL P Q+ Q
Sbjct: 428 QQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ 487
Query: 1033 SQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSR 1073
Q Q + L+ +QL Q L L Q + L Q +
Sbjct: 488 LQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQ 528
Score = 33.1 bits (74), Expect = 1.6
Identities = 30/105 (28%), Positives = 40/105 (38%), Gaps = 16/105 (15%)
Query: 408 PQSQAQP-QTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQ----------H 456
PQ Q QP Q + Q+ H Q +Q+A +QQH+ +QQ QQQ H
Sbjct: 484 PQQQLQPFQQQHALQQQFHQLQQ--HQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMH 541
Query: 457 QPTNWSALPSSAGPSPGPFG---QEKIPSPSFGQQTFSPQSSPMP 498
Q + S P Q ++P QQ Q P P
Sbjct: 542 QQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSP 586
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 97.4 bits (241), Expect = 7e-20
Identities = 68/158 (43%), Positives = 77/158 (48%), Gaps = 11/158 (6%)
Query: 564 SDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSS 623
S + Q PSV Q++ L QQQQQQ QQ QQQQ QQ Q QQ QQQ QQQ Q
Sbjct: 421 SAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHH 480
Query: 624 ISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
+ QQQQQ QQQ QQQ QQ+ Q QQ Q Q Q QPS P Q P + SP
Sbjct: 481 MQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPS--PRQHSPVASQITSP 538
Query: 684 LPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQ 721
+P Q+Q SQ Q Q Q V+ Q
Sbjct: 539 IPAIGSPQPASQQHQ---------SQIQSQTQTQVLSQ 567
Score = 93.6 bits (231), Expect = 1e-18
Identities = 67/153 (43%), Positives = 76/153 (49%), Gaps = 10/153 (6%)
Query: 564 SDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSS 623
S + S +Q PS+ Q Q QQQQQQQQQQ QQ QQQQ QQ Q QQ Q
Sbjct: 412 SSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQ-- 469
Query: 624 ISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
QQ QQQ QQ QQQQQ QQQ QQQ QQQ QQ+ Q Q + Q P
Sbjct: 470 ---QQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQ---SQP 523
Query: 684 LPLQQKLLLQQMQNQPIAGMGY-QVSQQQRQDQ 715
P Q + Q+ PI +G Q + QQ Q Q
Sbjct: 524 SPRQHSPVASQI-TSPIPAIGSPQPASQQHQSQ 555
Score = 77.0 bits (188), Expect = 9e-14
Identities = 82/253 (32%), Positives = 96/253 (37%), Gaps = 61/253 (24%)
Query: 519 PSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQ 578
P +Q G + Q Q L RS P P NQ + SV +
Sbjct: 356 PLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPM---------------NQIVTSVTIAA 400
Query: 579 NKPSLLH----------YTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQ 628
N PS + Q Q QQ Q Q QQQQQQQQQQ QQ
Sbjct: 401 NMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQM------ 454
Query: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQ------QQQQQQPSSQPAQSLPSQPLLRS 682
QQQQ QQ Q QQ QQQ QQQ QQ QQ Q + Q L +
Sbjct: 455 ----------QQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQ 504
Query: 683 PLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHS-VVGQNTGPSP---SPNPCSNPNTG 738
LQQ+L LQQ+Q+ Q Q QHS V Q T P P SP P S +
Sbjct: 505 ---LQQRLQLQQLQHM-------QHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQS 554
Query: 739 SGYMNSQQSLLNQ 751
+Q +L+Q
Sbjct: 555 QIQSQTQTQVLSQ 567
Score = 54.3 bits (129), Expect = 7e-07
Identities = 54/167 (32%), Positives = 66/167 (39%), Gaps = 67/167 (40%)
Query: 633 QSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLL 692
Q S S Q QQ Q Q QQQQQQQQQQ QQ QQQQ LQQ +
Sbjct: 426 QVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQ--------------------LQQHQMH 465
Query: 693 QQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQ 752
QQ+Q QQ Q QH Q + Q
Sbjct: 466 QQIQ-------------QQMQQQHF----------------------------QHHMQQH 484
Query: 753 LMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPP 799
L ++Q LQ+QI +Q+ Q LQQ++ Q Q +H S+P P
Sbjct: 485 LQQQQQHLQQQINQQQLQQQLQQRLQLQ------QLQHMQHQSQPSP 525
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/146 (27%), Positives = 54/146 (36%), Gaps = 4/146 (2%)
Query: 516 KAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVL 575
+ PS Q + +QQ+ Q + ++ Q + + M L
Sbjct: 426 QVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHL 485
Query: 576 PSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS 635
Q + QQQ QQQ QQ+ Q QQ Q Q Q Q +Q S A Q +
Sbjct: 486 QQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQH----SPVASQITSPIPA 541
Query: 636 ISAQQQQQQQQQQQQQQQQQQQQQQQ 661
I + Q QQ Q Q Q Q Q Q Q
Sbjct: 542 IGSPQPASQQHQSQIQSQTQTQVLSQ 567
Score = 31.2 bits (69), Expect = 6.0
Identities = 35/200 (17%), Positives = 73/200 (36%), Gaps = 15/200 (7%)
Query: 603 QQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQ 662
++Q+Q +++ + +++ +++A + + + + Q + QQ
Sbjct: 293 EEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLL 352
Query: 663 QQQPSSQPAQSLPSQPLLRSPLPLQ---QKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVV 719
P SQ S L+ LP + L ++ NQ + + + +
Sbjct: 353 LNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLIS 412
Query: 720 GQNT---GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQ 776
T G +PS + T M QQ ++Q Q+Q+ + +QQ L Q Q
Sbjct: 413 SMGTTMVGSAPSTQVSPSVQTQQHQMQLQQ---------QQQQQQQQMQQMQQQQLQQHQ 463
Query: 777 MLADAEKIAPQDQINRHLSR 796
M ++ Q H+ +
Sbjct: 464 MHQQIQQQMQQQHFQHHMQQ 483
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 97.4 bits (241), Expect = 7e-20
Identities = 68/158 (43%), Positives = 77/158 (48%), Gaps = 11/158 (6%)
Query: 564 SDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSS 623
S + Q PSV Q++ L QQQQQQ QQ QQQQ QQ Q QQ QQQ QQQ Q
Sbjct: 426 SAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHH 485
Query: 624 ISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
+ QQQQQ QQQ QQQ QQ+ Q QQ Q Q Q QPS P Q P + SP
Sbjct: 486 MQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPS--PRQHSPVASQITSP 543
Query: 684 LPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQ 721
+P Q+Q SQ Q Q Q V+ Q
Sbjct: 544 IPAIGSPQPASQQHQ---------SQIQSQTQTQVLSQ 572
Score = 93.6 bits (231), Expect = 1e-18
Identities = 67/153 (43%), Positives = 76/153 (49%), Gaps = 10/153 (6%)
Query: 564 SDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSS 623
S + S +Q PS+ Q Q QQQQQQQQQQ QQ QQQQ QQ Q QQ Q
Sbjct: 417 SSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQ-- 474
Query: 624 ISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
QQ QQQ QQ QQQQQ QQQ QQQ QQQ QQ+ Q Q + Q P
Sbjct: 475 ---QQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQ---SQP 528
Query: 684 LPLQQKLLLQQMQNQPIAGMGY-QVSQQQRQDQ 715
P Q + Q+ PI +G Q + QQ Q Q
Sbjct: 529 SPRQHSPVASQI-TSPIPAIGSPQPASQQHQSQ 560
Score = 77.0 bits (188), Expect = 9e-14
Identities = 82/253 (32%), Positives = 96/253 (37%), Gaps = 61/253 (24%)
Query: 519 PSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQ 578
P +Q G + Q Q L RS P P NQ + SV +
Sbjct: 361 PLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPM---------------NQIVTSVTIAA 405
Query: 579 NKPSLLH----------YTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQ 628
N PS + Q Q QQ Q Q QQQQQQQQQQ QQ
Sbjct: 406 NMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQM------ 459
Query: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQ------QQQQQQPSSQPAQSLPSQPLLRS 682
QQQQ QQ Q QQ QQQ QQQ QQ QQ Q + Q L +
Sbjct: 460 ----------QQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQ 509
Query: 683 PLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHS-VVGQNTGPSP---SPNPCSNPNTG 738
LQQ+L LQQ+Q+ Q Q QHS V Q T P P SP P S +
Sbjct: 510 ---LQQRLQLQQLQHM-------QHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQS 559
Query: 739 SGYMNSQQSLLNQ 751
+Q +L+Q
Sbjct: 560 QIQSQTQTQVLSQ 572
Score = 54.3 bits (129), Expect = 7e-07
Identities = 54/167 (32%), Positives = 66/167 (39%), Gaps = 67/167 (40%)
Query: 633 QSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLL 692
Q S S Q QQ Q Q QQQQQQQQQQ QQ QQQQ LQQ +
Sbjct: 431 QVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQ--------------------LQQHQMH 470
Query: 693 QQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQ 752
QQ+Q QQ Q QH Q + Q
Sbjct: 471 QQIQ-------------QQMQQQHF----------------------------QHHMQQH 489
Query: 753 LMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPP 799
L ++Q LQ+QI +Q+ Q LQQ++ Q Q +H S+P P
Sbjct: 490 LQQQQQHLQQQINQQQLQQQLQQRLQLQ------QLQHMQHQSQPSP 530
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/146 (27%), Positives = 54/146 (36%), Gaps = 4/146 (2%)
Query: 516 KAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVL 575
+ PS Q + +QQ+ Q + ++ Q + + M L
Sbjct: 431 QVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHL 490
Query: 576 PSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS 635
Q + QQQ QQQ QQ+ Q QQ Q Q Q Q +Q S A Q +
Sbjct: 491 QQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQH----SPVASQITSPIPA 546
Query: 636 ISAQQQQQQQQQQQQQQQQQQQQQQQ 661
I + Q QQ Q Q Q Q Q Q Q
Sbjct: 547 IGSPQPASQQHQSQIQSQTQTQVLSQ 572
Score = 31.2 bits (69), Expect = 6.0
Identities = 35/200 (17%), Positives = 73/200 (36%), Gaps = 15/200 (7%)
Query: 603 QQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQ 662
++Q+Q +++ + +++ +++A + + + + Q + QQ
Sbjct: 298 EEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLL 357
Query: 663 QQQPSSQPAQSLPSQPLLRSPLPLQ---QKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVV 719
P SQ S L+ LP + L ++ NQ + + + +
Sbjct: 358 LNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLIS 417
Query: 720 GQNT---GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQ 776
T G +PS + T M QQ ++Q Q+Q+ + +QQ L Q Q
Sbjct: 418 SMGTTMVGSAPSTQVSPSVQTQQHQMQLQQ---------QQQQQQQQMQQMQQQQLQQHQ 468
Query: 777 MLADAEKIAPQDQINRHLSR 796
M ++ Q H+ +
Sbjct: 469 MHQQIQQQMQQQHFQHHMQQ 488
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 94.4 bits (233), Expect = 6e-19
Identities = 65/142 (45%), Positives = 73/142 (51%), Gaps = 24/142 (16%)
Query: 544 NPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQ 603
+P AM P P+ + + Q P QN SL ++QQ+QQQQQQQQQQQ
Sbjct: 16 SPQGAMTPGIPIFSPMMPYGTGLTPQ------PIQNTNSL-SILEEQQRQQQQQQQQQQQ 68
Query: 604 QQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663
QQQQQQQQQQQQQQQQQQ QQQQQQQQQ QQ QQ
Sbjct: 69 QQQQQQQQQQQQQQQQQQ-----------------QQQQQQQQQAVAAAAVQQSTSQQAT 111
Query: 664 QQPSSQPAQSLPSQPLLRSPLP 685
Q S Q Q SQ L +PLP
Sbjct: 112 QGTSGQAPQLFHSQTLTTAPLP 133
Score = 67.0 bits (162), Expect = 1e-10
Identities = 50/141 (35%), Positives = 66/141 (46%), Gaps = 10/141 (7%)
Query: 628 QQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ 687
Q S + QQ+QQQQQQQQQQQQQQQQQQQQQQQQ Q Q Q + +Q
Sbjct: 44 QNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQ 103
Query: 688 QKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSP-------NPCSNPNTGSG 740
Q Q Q +G Q+ Q + G T PSP P + + SG
Sbjct: 104 QS--TSQQATQGTSGQAPQLFHSQTLTTAPLPG-TTPLYPSPMTPMTPITPATPASESSG 160
Query: 741 YMNSQQSLLNQQLMGKKQTLQ 761
+ Q++++ +G K L+
Sbjct: 161 IVPQLQNIVSTVNLGCKLDLK 181
Score = 32.7 bits (73), Expect = 2.0
Identities = 53/212 (25%), Positives = 81/212 (38%), Gaps = 16/212 (7%)
Query: 724 GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEK 783
G +P P N N+ S Q+ QQ ++Q Q+Q +Q+QQ QQQ ++
Sbjct: 35 GTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----QQ 89
Query: 784 IAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQAL-ANPVSTHTIL 842
Q Q + + + P +S +T L L +P++ T +
Sbjct: 90 QQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPI 149
Query: 843 TPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLAN 902
TP ++ S S G +P L V + NL C T + + NPK+ A
Sbjct: 150 TP-ATPASESSGI-VPQLQNIVSTV----NLGCKLD---LKTIALRARNAEYNPKRFAAV 200
Query: 903 QNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQ 934
PR L S+ V T GA S S+
Sbjct: 201 IMRIREPRTTALIFSSGKMVCT-GAKSEEQSR 231
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 91.3 bits (225), Expect = 5e-18
Identities = 168/696 (24%), Positives = 232/696 (33%), Gaps = 128/696 (18%)
Query: 493 QSSPMPGVAGGSGQSKVMANYMYKAGPSA--QGGHLDVLMQQKPQDLSRSFINNPHPAME 550
Q M G G ++ A + +GP V++ S P+P ++
Sbjct: 145 QDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQ 204
Query: 551 PRQGNTKP--------LFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQ----QQQQQQ 598
PR L + Q + S+ P + + +Q Q QQQQ
Sbjct: 205 PRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQ 264
Query: 599 QQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658
QQQQQQQQQQQQQQQQQQQQQ Q+ Q QQQQ I Q Q Q
Sbjct: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324
Query: 659 QQQQQQQPSSQPAQSLPSQPLLRSPLP------LQQKLLLQQMQNQPIAGMGYQVSQQQR 712
Q S + +Q ++PLP LQ + L +Q Y QQ
Sbjct: 325 ALQPPPAQGSLGTMT-ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQA 383
Query: 713 QDQH------SVVGQNT---------GPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK 757
H S GQ T GPS P P P+ + S S Q
Sbjct: 384 SQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASS 443
Query: 758 QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQ-INRHLSRP-----------PPDYKDQR 805
T+ + QQQM + P Q + +S P PP++ +
Sbjct: 444 PTVNQ----------TQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQ 493
Query: 806 RNVGNMQPTAQYSG----------GSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGT 855
+ N P + + G G S N N + V + T TP +S G
Sbjct: 494 QQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPN-FMQGQVPSTTATTPGNS------GA 546
Query: 856 RMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLG 915
+ VQ+ G G P NQ+ P P M +P +G
Sbjct: 547 PQLQANQNVQHAGGQGAGP-----------PQNQMQVSHGP---------PNMMQPSLMG 586
Query: 916 PSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGT-SK 974
N N AG+ G Q N+ PP + + + Q+GT +
Sbjct: 587 IHGNMN--NQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNP 644
Query: 975 QQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTP---AVQMRPMNQ 1031
Q + S P G P+Q+L S + + PP Q+ M P NQ
Sbjct: 645 QNPMILSRAQLMPQGQMMVNPPSQNLGP-------SPQRMTPPKQMLSQQGPQMMAPHNQ 697
Query: 1032 MSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNF---P 1088
M MGP + L+ N + QI+ N Q ++ N P P+ P
Sbjct: 698 M--------MGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG--PAQIMRGP 747
Query: 1089 SPNQSSRAFQGTDHSSDLAFDFLSQQNDNMGPALNS 1124
+PN Q T S Q GP NS
Sbjct: 748 TPNMQGNMVQFTGQMS-------GQMLPQQGPVNNS 776
Score = 71.2 bits (173), Expect = 5e-12
Identities = 233/1110 (20%), Positives = 369/1110 (33%), Gaps = 198/1110 (17%)
Query: 97 ATAATTTAPPPP-PAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQ 155
AT T + PPPP P ASQA P Q + S G S QQ
Sbjct: 364 ATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQ---MKSLQGGPSRVPTPLQQ 420
Query: 156 P------PASTPGD-QRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRV 208
P PAS+P Q+ S + + ++Q+ P N+ P GF
Sbjct: 421 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSP------ 474
Query: 209 GENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGL-------FNMG 261
G N QG + N + M Q P N P H G+ F+ G
Sbjct: 475 GRNPMVQQGNVPPN---------FMVMQQQP---PNQGPQSLHPGLGGMPKRLPPGFSAG 522
Query: 262 LKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQEL--FNELTNISVP 319
G+ S + G + N+ G Q P ++ + N+ P
Sbjct: 523 QANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQP 582
Query: 320 PMSDLELENMINATIKQDDPFNIDLGQ---QSQRSTPRPSLPMEKIVIKSEYSPGLTQG- 375
+ + NM N ++L Q Q+ P + M + ++ S+ QG
Sbjct: 583 SLMGIH-GNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGT 641
Query: 376 ---------------PSGSPQLRPPSA--GPA---FSMANSALSTSSPIPSVPQSQAQPQ 415
P G + PPS GP+ + LS P P +Q
Sbjct: 642 LNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGP 701
Query: 416 TGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPF 475
G + P ++QI N+ Q + Q + Q GP+P
Sbjct: 702 QGQVLLQQNP---------MIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ 752
Query: 476 GQE-KIPSPSFGQQTFSPQSSPMPG----VAGGSGQ-------SKVMANYMYKAGPSAQG 523
G + GQ PQ P+ V G GQ S MA + G A
Sbjct: 753 GNMVQFTGQMSGQML--PQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQ---QHGDPATT 807
Query: 524 GHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMP-SVLPSQNKPS 582
+ DV + Q D+S N P ++ QGN+ HF+ + P S P+ N+ S
Sbjct: 808 ANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMS 867
Query: 583 LLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQ 642
Q + QS ISA Q
Sbjct: 868 C--------------GQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNK----QNNT 909
Query: 643 QQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQ-------QM 695
+ ++++ ++++ QQ P ++PA + + PLP +Q + L +
Sbjct: 910 NANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEAD---QPPLPGEQGINLDNSGPKLPEF 966
Query: 696 QNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMG 755
N+P V Q+ Q + Q+ P P P P P Q QQ
Sbjct: 967 SNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQP-PQQQPQP--------QLPQQQQPPP 1017
Query: 756 KKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQR---RNVGNMQ 812
Q +Q +Q+QQ+++ M D + + N H R P + QR + G++
Sbjct: 1018 PSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVP 1077
Query: 813 PTAQYSGGSSTISLNSNQALANPVST------------HTILTPNSSLLS------TSHG 854
G +S Q + PV+T + P+SS L+ + G
Sbjct: 1078 VMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASG 1137
Query: 855 TRMPSLSTAVQNMGMYGNLPCNQ---------PNTYSVTSG-------MNQL-------- 890
+ PS+ NM + LP NQ P+ S T G +N L
Sbjct: 1138 SEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHF 1197
Query: 891 ------TQQRNPKQLLANQNNPMMP-----RPPTLGPSN--------NNNVATFGAGSVG 931
TQ PK P P RPP+ PS N ++A +
Sbjct: 1198 PNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQIN 1257
Query: 932 NSQQLRPNLTHSMASMPPQRTSNVMI----TSNTTAPNWASQEGTSKQQEALTSAGVRFP 987
RPNL T+ I ++ T P+ + T K + ++G +
Sbjct: 1258 IPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSN 1317
Query: 988 TGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGPLRGL 1047
+G +P+ S + + GS + + +P Q + A ++ +Q + L P R +
Sbjct: 1318 SGATKRASPSNSRRSSPGSSR--KTTPSPGRQNSKAPKLTLASQTNAALLQNVELP-RNV 1374
Query: 1048 NLRPNQLSTQILPNLNQSGTGLNQSRTGIN 1077
+ P L+ +P + +GLN + ++
Sbjct: 1375 LVSPTPLANPPVPGSFPNNSGLNPQNSTVS 1404
Score = 69.7 bits (169), Expect = 2e-11
Identities = 191/847 (22%), Positives = 283/847 (33%), Gaps = 140/847 (16%)
Query: 346 QQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIP 405
QQ Q+ P+ P + PG Q PSG+ Q PP+ G +M + +P+P
Sbjct: 292 QQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQ-PPPAQGSLGTMTANQGWKKAPLP 350
Query: 406 SVPQSQAQ------------------PQTGSGASRALPSWQEVSHAQQL--KQIAANRQQ 445
Q Q Q P AS+A ++ ++S+ Q Q+ + +
Sbjct: 351 GPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGG 410
Query: 446 HARMQQHQQQHQPTNWSALPS-------SAGPSP---------GPFGQEKIPSP-SFGQQ 488
+R+ QQ TN S S S SP GP + P P F Q
Sbjct: 411 PSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQP 470
Query: 489 TFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSR-----SFIN 543
SP +PM VM GP + L + ++ P S +F+
Sbjct: 471 VSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQ 530
Query: 544 NPHPA-MEPRQGNT-KPLFHFNSD------------QANQQMPSVLPSQNKPSLLHYTQQ 589
P+ GN+ P N + Q Q+ P+ +PSL+
Sbjct: 531 GQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGN 590
Query: 590 QQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQ 644
QQ Q Q Q QQ Q QQ S Q QQQ +++ Q
Sbjct: 591 MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMIL 650
Query: 645 QQQQQQQQQQQQQQQQQQQQQPSSQ----PAQSLPSQ-PLLRSP----------LPLQQK 689
+ Q Q Q Q PS Q P Q L Q P + +P + LQQ
Sbjct: 651 SRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQN 710
Query: 690 LLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQ-NTGPSPSPNPCSNPNTG--SGYMNSQQ 746
+++Q+ + G Q + Q + + Q GP+P+ TG SG M QQ
Sbjct: 711 PMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQ 770
Query: 747 SLLN---QQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKD 803
+N Q+MG +Q Q++ Q D A D LS+ PD
Sbjct: 771 GPVNNSPSQVMG----IQGQVLRPPGPSPHMAQQHGDPATTANNDV---SLSQMMPDVSI 823
Query: 804 QRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTA 863
Q+ N+ + P Q ++ N A N S H ++ N+ +G +M
Sbjct: 824 QQTNM--VPPHVQ--------AMQGNSASGNHFSGHG-MSFNAPFSGAPNGNQM------ 866
Query: 864 VQNMGMYGNLPCNQPNTYSVTSGMNQLTQQ-------RNPKQLLANQNNPMMPRPPTLGP 916
+ G P N+ T + +N L N KQ N N P +PP
Sbjct: 867 --SCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKK 924
Query: 917 SNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQ 976
++ ++ T G + +P L + SN P + SQ +
Sbjct: 925 NSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSN-RPPGYPSQPVEQRPL 983
Query: 977 EALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTL 1036
+ + P P Q QQ Q Q+ PP+Q Q + QM L
Sbjct: 984 QQMP------PQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML 1037
Query: 1037 N------------GQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTG-INQPPSLT 1083
Q + P RG P +Q +P + S G + PPS
Sbjct: 1038 MMQQDPKSVRLPVSQNVHPPRG----PLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPD 1093
Query: 1084 PSNFPSP 1090
P P
Sbjct: 1094 KQRMPMP 1100
Score = 63.9 bits (154), Expect = 8e-10
Identities = 139/658 (21%), Positives = 217/658 (32%), Gaps = 121/658 (18%)
Query: 519 PSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQ 578
P QG +LD + P+ F N P P + +PL QQMP L
Sbjct: 949 PGEQGINLDNSGPKLPE-----FSNRP-PGYPSQPVEQRPL---------QQMPPQLMQH 993
Query: 579 NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISA 638
P Q QQQ Q Q QQQQ Q Q QQQQQQQQQ + QQ +S
Sbjct: 994 VAPP----PQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLP 1049
Query: 639 QQQQQQQQQQQQQQQQQQQQQQQQQQQP----SSQPAQSLPSQPLLRSPLPL-------Q 687
Q + Q+ QQ P PA PS R P+P+
Sbjct: 1050 VSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109
Query: 688 QKLLLQQMQNQPIAGMGYQVSQ---------------QQRQDQHSVVGQN----TGPSPS 728
+K++ Q+ P + +++ H V+ QN TGP P
Sbjct: 1110 RKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPG 1169
Query: 729 PNPCSN----------------------PNTGSGYMNSQQSLLN----QQLMGKKQTLQR 762
P+P S PN + S+ N + + +
Sbjct: 1170 PSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRP 1229
Query: 763 QIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSS 822
E + L +++ A + P QIN + PP ++ + + PT + G +
Sbjct: 1230 PSTEPSEISLSPERLNASIAGLFP-PQIN--IPLPPRPNLNRGFDQQGLNPTTLKAIGQA 1286
Query: 823 TISLNSNQALANPVSTHTI--LTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNT 880
+L N + TH + + NS S S T+ S S + ++ P
Sbjct: 1287 PSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGR 1346
Query: 881 YSVTSGMNQLTQQRN---------PKQLLANQNNPMMPRPPTLGPSN------NNNVATF 925
+ + L Q N P+ +L + P P P+N N+ V+
Sbjct: 1347 QNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVA 1406
Query: 926 GAGSV----------------GNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQ 969
G V NSQ + + + ++P Q V+ + + +
Sbjct: 1407 AVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVV------PEDQSKK 1460
Query: 970 EGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPM 1029
+G L S +PA SL Q + + + PP LT P+
Sbjct: 1461 DGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPG-LTDLEVTPPV 1519
Query: 1030 NQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGL---NQSRTGINQPPSLTP 1084
+ L+ L+ ++ LP+ N+ + L S N PS+ P
Sbjct: 1520 VSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPP 1577
Score = 60.8 bits (146), Expect = 7e-09
Identities = 156/705 (22%), Positives = 220/705 (31%), Gaps = 156/705 (22%)
Query: 376 PSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVS---- 431
P +P+L+P + PA S P+ S Q Q + Q VS
Sbjct: 197 PGPNPELQPRTPRPA-----SQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQ 251
Query: 432 ------------HAQQLKQIAANRQQHARMQQHQ------QQHQ---------------- 457
QQ +Q +QQ + QQ Q QQHQ
Sbjct: 252 MNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQ 311
Query: 458 ---PTNWSALPSSA---------------------GPSPGPFGQEKIPSPSFGQQTFSPQ 493
P W+ LPS A P PGP Q+ PS +P
Sbjct: 312 VPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA-TVQTPS 370
Query: 494 SSPMPGVAGGSGQSKVMANYMYKAGP---------SAQGGHLDVLMQQKPQDLSRSFINN 544
P P G S+ N+ + P S QGG V P L + + N
Sbjct: 371 HPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRV-----PTPLQQPHLTN 425
Query: 545 PHPAMEP---RQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQ 601
PA P +QG+ P +Q QQM P QN P + Q + QQ
Sbjct: 426 KSPASSPSSFQQGS--PASSPTVNQTQQQM-GPRPPQNNPLPQGFQQPVSSPGRNPMVQQ 482
Query: 602 QQQQQQQQQQQQQQQQQQQQS--------------SISAQQ-----QQQQQSSISAQQQQ 642
QQQ Q QS SA Q Q Q S +A
Sbjct: 483 GNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPG 542
Query: 643 QQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLL---QQMQNQP 699
Q Q Q Q Q P +Q S P + Q L+ M NQ
Sbjct: 543 NSGAPQLQANQNVQHAGGQGAGPPQNQMQVS-------HGPPNMMQPSLMGIHGNMNNQQ 595
Query: 700 IAGMG---YQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGK 756
G +S Q Q Q Q G P G M QQ LN
Sbjct: 596 AGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVP------SQGQMVQQQGTLNP----- 644
Query: 757 KQTLQRQIMEQKQQLLLQQQMLAD--AEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPT 814
Q ++ + QL+ Q QM+ + ++ + P Q PP ++ M P
Sbjct: 645 ----QNPMILSRAQLMPQGQMMVNPPSQNLGPSPQ-----RMTPPKQMLSQQGPQMMAPH 695
Query: 815 AQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLP 874
Q G + L N + + T+ + + + MP + M G P
Sbjct: 696 NQMMGPQGQVLLQQN-PMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQI-----MRGPTP 749
Query: 875 CNQPNTYSVTSGMN--QLTQQ----RNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAG 928
Q N T M+ L QQ +P Q++ Q + P P+ + + A
Sbjct: 750 NMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTAN 809
Query: 929 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTS 973
+ + Q+ P+++ +M P + N+ + N S G S
Sbjct: 810 NDVSLSQMMPDVSIQQTNMVPPHVQ--AMQGNSASGNHFSGHGMS 852
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 89.7 bits (221), Expect = 1e-17
Identities = 177/779 (22%), Positives = 258/779 (33%), Gaps = 152/779 (19%)
Query: 365 KSEYSPGLTQGPSGSPQLRPPSAGPAFSMAN-----SALSTSSPIPSVPQSQAQPQTGSG 419
+S Y P SP+ P +G A + + S+ S SS S Q + G G
Sbjct: 219 RSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGG 278
Query: 420 ASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEK 479
S A + + L Q+ + + Q + ++S P G GP
Sbjct: 279 PSAAGGGTPQPTATPTLNQLLTSPSS----ARGYQGYPGGDYSGGPQDGGAGKGPADMAS 334
Query: 480 -----------IPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDV 528
+ S G Q S + PG +GG GQ +A + P Q G
Sbjct: 335 QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP--LARTPQPSSPMDQMGK--- 389
Query: 529 LMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSL--LHY 586
M+ +P + + P P+QG+ P + S Q Q+ P + + + ++ L Y
Sbjct: 390 -MRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS-QTPQRYPMTMQGRAQSAMGGLSY 447
Query: 587 TQQ-------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQ- 632
TQQ QQ Q QQ QQQQ QQ Q + S QQQ Q
Sbjct: 448 TQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQ 507
Query: 633 ----QSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ 688
QSS QQ Q QQ QQ QQ P SQP SQP +SP QQ
Sbjct: 508 PPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPY---SQPQAQSPYQQQQ 564
Query: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSL 748
QQ ++ Q +Q Q + Q P P
Sbjct: 565 P---QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE------------------- 602
Query: 749 LNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNV 808
L+Q G + + + K Q+ +N L P D ++
Sbjct: 603 LSQDSFGSQASSAPSMTSSK----------------GGQEDMNLSLQSRPSSLPDLSGSI 646
Query: 809 --------GNMQPTAQYSGGSSTISLNSNQALANPVSTHT----------ILTPNSSLLS 850
G + P SG SS+ SN A +P S HT +P S S
Sbjct: 647 DDLPMGTEGALSPGVSTSGISSSQGEQSNPA-QSPFSPHTSPHLPGIRGPSPSPVGSPAS 705
Query: 851 TSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPR 910
+ P AV M P Q ++ S MNQ + ++ + Q NP MP+
Sbjct: 706 VAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS-MNQSSIAQDRGYM---QRNPQMPQ 761
Query: 911 PPTLGPSNNNNVATFGAGSV----GNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNW 966
+ P + + G + G+ QQ +SM S PQ +
Sbjct: 762 YSSPQPGSALSPRQPSGGQIHTGMGSYQQ------NSMGSYGPQ------------GGQY 803
Query: 967 ASQEGTSKQQEALTSAGVRFPT-GTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPA-V 1024
Q G +Q +P+ G P + Q G PP +++ A +
Sbjct: 804 GPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASM 863
Query: 1025 QMRP----MNQMSQTLNGQTMGPLRGLNLRPNQLSTQI-------------LPNLNQSG 1066
RP M M + P G+N + + + + PN+NQ G
Sbjct: 864 GNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGG 922
Score = 57.0 bits (136), Expect = 1e-07
Identities = 73/321 (22%), Positives = 113/321 (35%), Gaps = 55/321 (17%)
Query: 380 PQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQI 439
P+++PPS + SM P PQS + G + P+ H+Q
Sbjct: 1128 PKIQPPSPAGSGSMQG---------PQTPQSTSSSMAEGGDLKP-PTPASTPHSQIPPLP 1177
Query: 440 AANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPG 499
+R +Q + + +S P+PG + S G+ ++ P P
Sbjct: 1178 GMSRSNSVGIQDAFNDGSDSTFQKR-NSMTPNPG-YQPSMNTSDMMGRMSYEPNKDPYGS 1235
Query: 500 VAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQG----- 554
+ G M++ G GG D + L + AM PRQ
Sbjct: 1236 MRKAPGSDPFMSS-----GQGPNGGMGDPYSRAAGPGLG-------NVAMGPRQHYPYGG 1283
Query: 555 -----NTKPLFHFNSDQAN-QQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQ------- 601
T+P + + P+++PS + ++ QQQQQQQQ+
Sbjct: 1284 PYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQF 1343
Query: 602 -------------QQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQ 648
QQ QQQQQ ++ A++ + + S+ Q Q QQQ
Sbjct: 1344 STQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQ 1403
Query: 649 QQQQQQQQQQQQQQQQQPSSQ 669
Q Q Q QQQ QPS Q
Sbjct: 1404 QLPPAQPQPASQQQAAQPSPQ 1424
Score = 50.1 bits (118), Expect = 1e-05
Identities = 163/764 (21%), Positives = 236/764 (30%), Gaps = 133/764 (17%)
Query: 6 PPQAPAGGL----GGASGAGLLGG-GSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER 60
PP APA L GG G+G GS P SA + A R + G
Sbjct: 223 PPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAA 282
Query: 61 GRAESSDRERESTLQLLSLVQHGQGAR--KAGKHTKATATAATTTAPPPPPAAPPAASQA 118
G + QLL+ +G + G ++ P + A+ A
Sbjct: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342
Query: 119 AATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKR 178
AA AA H H S + G GG + P S+P DQ G
Sbjct: 343 AAAAAAASGGAQQRSH--HAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNP 400
Query: 179 KQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQA 238
P+ ++ +G+ + G Q M G +
Sbjct: 401 YSQQQGPPSGPQQGHGYPGQPY-----------------GSQTPQRYPMTMQGRAQSAMG 443
Query: 239 PLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPG 298
L T +P + +G G + S H Q Y P
Sbjct: 444 GLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQ------SPHPQQQQPP-------YSQQPP 490
Query: 299 EQLMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLP 358
Q P Q + + P + + P++ Q + +P P
Sbjct: 491 SQT--PHAQPSYQQQPQSQPPQLQSSQ------------PPYSQQPSQPPHQQSPAPYPS 536
Query: 359 MEKIVIKSEYSPGLTQGPSGSPQLRPP-SAGPAFSMANSALSTSSPIPSVPQSQAQPQTG 417
+ + S Q P PQ + P A S LS + P PQSQ QT
Sbjct: 537 QQSTTQQHPQS----QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQ-PQSQQSQQTA 591
Query: 418 SGASRALPSWQEVSHAQQLKQIAANRQQHARM--QQHQQQHQPTNWSALPSSAGPSPG-P 474
R P QE+S Q ++ + Q+ + S+LP +G P
Sbjct: 592 YSQQR-FPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP 650
Query: 475 FGQEKIPSP---------SFGQQT------FSPQSSP-MPGVAGGSGQSKVMANYMYKAG 518
G E SP S G+Q+ FSP +SP +PG+ G S
Sbjct: 651 MGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS-------------- 696
Query: 519 PSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQ 578
PS G P +++S PA P GN QMP PS
Sbjct: 697 PSPVGS---------PASVAQSRSGPLSPAAVP--GN--------------QMPPRPPSG 731
Query: 579 NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQ--QQQSSI 636
S++H Q Q + Q+ Q Q Q S++S +Q Q + +
Sbjct: 732 QSDSIMH------PSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGM 785
Query: 637 SAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696
+ QQ Q Q Q +Q ++ P + PS + P+ QM
Sbjct: 786 GSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG---GQMH 842
Query: 697 NQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSG 740
QP Y R S+ + GP+ + P P GSG
Sbjct: 843 GQP-GIPPYGTLPPGRMSHASMGNRPYGPNMANMP---PQVGSG 882
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 89.7 bits (221), Expect = 1e-17
Identities = 177/779 (22%), Positives = 258/779 (33%), Gaps = 152/779 (19%)
Query: 365 KSEYSPGLTQGPSGSPQLRPPSAGPAFSMAN-----SALSTSSPIPSVPQSQAQPQTGSG 419
+S Y P SP+ P +G A + + S+ S SS S Q + G G
Sbjct: 219 RSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGG 278
Query: 420 ASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEK 479
S A + + L Q+ + + Q + ++S P G GP
Sbjct: 279 PSAAGGGTPQPTATPTLNQLLTSPSS----ARGYQGYPGGDYSGGPQDGGAGKGPADMAS 334
Query: 480 -----------IPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDV 528
+ S G Q S + PG +GG GQ +A + P Q G
Sbjct: 335 QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP--LARTPQPSSPMDQMGK--- 389
Query: 529 LMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSL--LHY 586
M+ +P + + P P+QG+ P + S Q Q+ P + + + ++ L Y
Sbjct: 390 -MRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS-QTPQRYPMTMQGRAQSAMGGLSY 447
Query: 587 TQQ-------------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQ- 632
TQQ QQ Q QQ QQQQ QQ Q + S QQQ Q
Sbjct: 448 TQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQ 507
Query: 633 ----QSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ 688
QSS QQ Q QQ QQ QQ P SQP SQP +SP QQ
Sbjct: 508 PPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPY---SQPQAQSPYQQQQ 564
Query: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSL 748
QQ ++ Q +Q Q + Q P P
Sbjct: 565 P---QQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQE------------------- 602
Query: 749 LNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNV 808
L+Q G + + + K Q+ +N L P D ++
Sbjct: 603 LSQDSFGSQASSAPSMTSSK----------------GGQEDMNLSLQSRPSSLPDLSGSI 646
Query: 809 --------GNMQPTAQYSGGSSTISLNSNQALANPVSTHT----------ILTPNSSLLS 850
G + P SG SS+ SN A +P S HT +P S S
Sbjct: 647 DDLPMGTEGALSPGVSTSGISSSQGEQSNPA-QSPFSPHTSPHLPGIRGPSPSPVGSPAS 705
Query: 851 TSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPR 910
+ P AV M P Q ++ S MNQ + ++ + Q NP MP+
Sbjct: 706 VAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS-MNQSSIAQDRGYM---QRNPQMPQ 761
Query: 911 PPTLGPSNNNNVATFGAGSV----GNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNW 966
+ P + + G + G+ QQ +SM S PQ +
Sbjct: 762 YSSPQPGSALSPRQPSGGQIHTGMGSYQQ------NSMGSYGPQ------------GGQY 803
Query: 967 ASQEGTSKQQEALTSAGVRFPT-GTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPA-V 1024
Q G +Q +P+ G P + Q G PP +++ A +
Sbjct: 804 GPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASM 863
Query: 1025 QMRP----MNQMSQTLNGQTMGPLRGLNLRPNQLSTQI-------------LPNLNQSG 1066
RP M M + P G+N + + + + PN+NQ G
Sbjct: 864 GNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGG 922
Score = 50.1 bits (118), Expect = 1e-05
Identities = 163/764 (21%), Positives = 236/764 (30%), Gaps = 133/764 (17%)
Query: 6 PPQAPAGGL----GGASGAGLLGG-GSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER 60
PP APA L GG G+G GS P SA + A R + G
Sbjct: 223 PPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAA 282
Query: 61 GRAESSDRERESTLQLLSLVQHGQGAR--KAGKHTKATATAATTTAPPPPPAAPPAASQA 118
G + QLL+ +G + G ++ P + A+ A
Sbjct: 283 GGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAA 342
Query: 119 AATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKR 178
AA AA H H S + G GG + P S+P DQ G
Sbjct: 343 AAAAAAASGGAQQRSH--HAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNP 400
Query: 179 KQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQA 238
P+ ++ +G+ + G Q M G +
Sbjct: 401 YSQQQGPPSGPQQGHGYPGQPY-----------------GSQTPQRYPMTMQGRAQSAMG 443
Query: 239 PLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPG 298
L T +P + +G G + S H Q Y P
Sbjct: 444 GLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQ------SPHPQQQQPP-------YSQQPP 490
Query: 299 EQLMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLP 358
Q P Q + + P + + P++ Q + +P P
Sbjct: 491 SQT--PHAQPSYQQQPQSQPPQLQSSQ------------PPYSQQPSQPPHQQSPAPYPS 536
Query: 359 MEKIVIKSEYSPGLTQGPSGSPQLRPP-SAGPAFSMANSALSTSSPIPSVPQSQAQPQTG 417
+ + S Q P PQ + P A S LS + P PQSQ QT
Sbjct: 537 QQSTTQQHPQS----QPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQ-PQSQQSQQTA 591
Query: 418 SGASRALPSWQEVSHAQQLKQIAANRQQHARM--QQHQQQHQPTNWSALPSSAGPSPG-P 474
R P QE+S Q ++ + Q+ + S+LP +G P
Sbjct: 592 YSQQR-FPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP 650
Query: 475 FGQEKIPSP---------SFGQQT------FSPQSSP-MPGVAGGSGQSKVMANYMYKAG 518
G E SP S G+Q+ FSP +SP +PG+ G S
Sbjct: 651 MGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPS-------------- 696
Query: 519 PSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQ 578
PS G P +++S PA P GN QMP PS
Sbjct: 697 PSPVGS---------PASVAQSRSGPLSPAAVP--GN--------------QMPPRPPSG 731
Query: 579 NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQ--QQQSSI 636
S++H Q Q + Q+ Q Q Q S++S +Q Q + +
Sbjct: 732 QSDSIMH------PSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGM 785
Query: 637 SAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696
+ QQ Q Q Q +Q ++ P + PS + P+ QM
Sbjct: 786 GSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG---GQMH 842
Query: 697 NQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSG 740
QP Y R S+ + GP+ + P P GSG
Sbjct: 843 GQP-GIPPYGTLPPGRMSHASMGNRPYGPNMANMP---PQVGSG 882
Score = 42.4 bits (98), Expect = 0.003
Identities = 63/316 (19%), Positives = 106/316 (33%), Gaps = 38/316 (12%)
Query: 380 PQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQI 439
P+++PPS + SM P PQS + G + P+ H+Q
Sbjct: 1128 PKIQPPSPAGSGSMQG---------PQTPQSTSSSMAEGGDLKP-PTPASTPHSQIPPLP 1177
Query: 440 AANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPG 499
+R +Q + + +S P+PG + S G+ ++ P P
Sbjct: 1178 GMSRSNSVGIQDAFNDGSDSTFQKR-NSMTPNPG-YQPSMNTSDMMGRMSYEPNKDPYGS 1235
Query: 500 VAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQG----- 554
+ G M++ G GG D + L + AM PRQ
Sbjct: 1236 MRKAPGSDPFMSS-----GQGPNGGMGDPYSRAAGPGLG-------NVAMGPRQHYPYGG 1283
Query: 555 -----NTKPLFHFNSDQAN-QQMPSVLPSQNKPSLL---HYTQQQQQQQQQQQQQQQQQQ 605
T+P + + P+++PS + Y QQQQQQQQ+ Q
Sbjct: 1284 PYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQF 1343
Query: 606 QQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQ 665
Q QQ + QQQ + + + + + + Q+
Sbjct: 1344 STQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV 1403
Query: 666 PSSQPAQSLPSQPLLR 681
P+S A + P++R
Sbjct: 1404 PASHIAPAPVQPPMIR 1419
Score = 32.0 bits (71), Expect = 3.5
Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 31/90 (34%)
Query: 650 QQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQ 709
QQQQQQQQ+ Q S+Q S SP P QQ + QQ Q
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPS-------GSPFPSQQTTMYQQQQ------------- 1366
Query: 710 QQRQDQHSVVGQNTGPSPSPNPCSNPNTGS 739
Q + P+P P P N + S
Sbjct: 1367 -----------QVSSPAPLPRPMENRTSPS 1385
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 87.4 bits (215), Expect = 7e-17
Identities = 85/272 (31%), Positives = 115/272 (42%), Gaps = 54/272 (19%)
Query: 522 QGGHLDVLMQQKPQDLSRSFINNPHPAM-EPRQGN-----TKPLFHFNSDQANQQMPSVL 575
QG V+M QK +PA P QG P F+ +Q NQQ L
Sbjct: 1096 QGQEAAVMMDQKA-----GLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPL 1150
Query: 576 -----------PSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQ-----------QQ 613
P N P L QQ+ Q QQ Q +Q + + +
Sbjct: 1151 QGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMM 1210
Query: 614 QQQQQQQQSSISAQQQ------------QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQ 661
Q Q QQ ++AQ +QQ+ ++ QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 1211 QPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQ 1270
Query: 662 QQQQPSSQ---PAQSLPSQPLLRSPL--PLQQKLLLQQMQNQPIAGMGYQVSQ---QQRQ 713
QQQQ +Q P ++ + P + L P + QQ QP GMG Q +
Sbjct: 1271 QQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSS 1330
Query: 714 DQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745
++++ GPS +P +P S Y +S+
Sbjct: 1331 PPNAMMSSRMGPSQNP-MMQHPQAASIYQSSE 1361
Score = 45.8 bits (107), Expect = 2e-04
Identities = 142/720 (19%), Positives = 255/720 (35%), Gaps = 96/720 (13%)
Query: 150 INGEQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVG 209
++ ++ +S G + + +G K Q++ S + R + + NS LD
Sbjct: 593 LSDKESKESSVEGAENQRGPLESKGHKKLLQLLTCS--SDDRGHSSLTNSPLDSSCKESS 650
Query: 210 ENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEP 269
++++ G +++ S +S T M + L++ + + GN + +
Sbjct: 651 VSVTSPSG---VSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATG 707
Query: 270 GETLSCSKHMDGQMT-QENIFPN--------RY---GDDPGEQL---MDPELQELFNELT 314
+T S + DG + QE + P RY DDP + L + P+++ + N+++
Sbjct: 708 KDTSSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMS 767
Query: 315 NI--SVPPMSDLELENMINATIKQDDPFNID-----LGQQSQR-------STPRPSLPME 360
S P S E + I ++ ++D LG + S+ L +
Sbjct: 768 QCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTK 827
Query: 361 KIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSV---PQSQAQPQTG 417
+ V + S GL S +RPP + ++ +S P+ ++ P QP G
Sbjct: 828 QQVFQGTNSLGLKSSQSVQ-SIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLG 886
Query: 418 SGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQ 477
G R + S + + NR Q +W LP+S P
Sbjct: 887 -GNPRMMDSQENYGSSMG----GPNRNVTVT-----QTPSSGDWG-LPNSKAGRMEPMNS 935
Query: 478 EKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDL 537
+ P T S P P + G + +N + A P Q ++Q +P ++
Sbjct: 936 NSMGRPGGDYNT----SLPRPALGGSIPTLPLRSNSIPGARPVLQ--QQQQMLQMRPGEI 989
Query: 538 SRSFINNPHP----------------AMEPRQGNT--KPLFHFNSDQANQQMPSVLPSQN 579
NP+ +ME T +PL + D PS L Q+
Sbjct: 990 PMGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGP-PSNLEGQS 1048
Query: 580 KP--------SLLHYTQQQQQQQQQQQQ--QQQQQQQQQQQQQQQQQQQQQQSSISAQQQ 629
+LL T ++ + + Q Q + +Q Q Q+ + + Q+
Sbjct: 1049 DERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKA 1108
Query: 630 QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQK 689
+ AQ Q Q Q Q Q + P Q + + + P K
Sbjct: 1109 GLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPK 1168
Query: 690 LLLQQMQNQPIAGMGYQVSQQQRQD-QHSVVGQNTGPSPSPNPCSNPNTGS--GYMNSQ- 745
L Q+Q + G Q Q RQ + + G + P P S G++N+Q
Sbjct: 1169 QLRMQLQQRL---QGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQM 1225
Query: 746 -----QSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPD 800
+ LL+ ++ + Q +Q+QQ QQQ ++ Q Q PPP+
Sbjct: 1226 VAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPN 1285
Score = 34.7 bits (78), Expect = 0.54
Identities = 48/214 (22%), Positives = 75/214 (35%), Gaps = 46/214 (21%)
Query: 336 QDDPFNIDLGQQSQRST-------PRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAG 388
Q FN + Q +Q+ PR ++ + + L Q G L
Sbjct: 1131 QSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQA 1190
Query: 389 PAFSMANSALSTSSPIPSVPQSQAQPQTG--SGASRALPSWQEVSHAQQLKQIAANRQQH 446
M N ++ + + Q Q Q G + A S + +SH + +++A QQ
Sbjct: 1191 LELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQ 1250
Query: 447 ARMQQHQQQHQ---------------------PTNWSALPSSAGPSPGP----------- 474
+ QQ QQQ Q P N +A PS G GP
Sbjct: 1251 QQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFP 1310
Query: 475 ----FGQEKIPSPSFGQQTFSPQSSPMPGVAGGS 504
+G + P P+FG+ + SP ++ M G S
Sbjct: 1311 YQPNYGMGQQPDPAFGRVS-SPPNAMMSSRMGPS 1343
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 87.4 bits (215), Expect = 7e-17
Identities = 139/535 (25%), Positives = 193/535 (36%), Gaps = 134/535 (25%)
Query: 349 QRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVP 408
Q+S P P+ + +P Q P+ PQ P S PA +++ + P +V
Sbjct: 1841 QQSLPSPTSAPPGTPTQQPSTPQTPQPPA-QPQPSPVSMSPA---GFPSVARTQPPTTVS 1896
Query: 409 QSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSA 468
+ Q + A P V A+Q+++ A +Q R+ + P S
Sbjct: 1897 TGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQ 1956
Query: 469 G-------PSPGPFGQEKIPS--PSFGQQTFSPQSSPMPG-------------VAGG--- 503
P P +PS P QQ PQ PMPG VAG
Sbjct: 1957 MAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMP 2016
Query: 504 ----------SGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFI---------NN 544
S ++ + P Q L++L + PQ L +FI N
Sbjct: 2017 SVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL-KSNPQ-LMAAFIKQRTAKYVANQ 2074
Query: 545 P----------HPAMEPRQG--NTKPLFHFNSDQANQQMPSVLPSQ-------------- 578
P P M+P+ G L + N+ QA P V P Q
Sbjct: 2075 PGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALN 2134
Query: 579 -----NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---------------Q 618
+ P++ Q ++ ++Q QQQQQQQQQQQQQQQQQQ Q
Sbjct: 2135 IMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQ 2194
Query: 619 QQQS------SISAQQQQQQ----QSSISAQQQQQQQQ-----------------QQQQQ 651
Q Q ++ QQ+ QQ Q S Q Q Q QQ Q
Sbjct: 2195 QPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQ 2254
Query: 652 QQQQQQQQQQQQQQPSSQPAQSLPSQPLLR-----SPLPLQQKLLLQQMQNQPIAGMGYQ 706
Q+ QQQQ +QQ QP P Q +L S LP QQ + + NQ + Q
Sbjct: 2255 QRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQ--IATSLSNQVRSPAPVQ 2312
Query: 707 VSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGS---GYMNSQQSLLNQQLMGKKQ 758
+ Q Q HS P PSP+ S P TGS G + S ++Q +G +
Sbjct: 2313 SPRPQSQPPHSSPSPRIQPQPSPHHVS-PQTGSPHPGLAVTMASSIDQGHLGNPE 2366
Score = 47.4 bits (111), Expect = 8e-05
Identities = 81/361 (22%), Positives = 115/361 (31%), Gaps = 53/361 (14%)
Query: 370 PGLTQGPSGSPQLRPPSAGPAFSMAN-SALSTSSPIPSVPQSQAQPQTGSGASRALPSWQ 428
PGL P PQ P S+ N +A+ P P VP Q Q G +
Sbjct: 2081 PGLQSQPGMQPQ---PGMHQQPSLQNLNAMQAGVPRPGVPPQQ-QAMGGLNPQGQALNIM 2136
Query: 429 EVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQ 488
H + + ++ R Q QQQ Q QQ
Sbjct: 2137 NPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQ-------------------------QQ 2171
Query: 489 TFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPA 548
Q G+AGG MA + P GG+ + QQ+
Sbjct: 2172 QQQQQQQGSAGMAGG------MAGHGQFQQPQGPGGYPPAMQQQQRMQQHL--------- 2216
Query: 549 MEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQ 608
P QG++ Q Q L + + P++ QQ+ QQQQ +QQ Q
Sbjct: 2217 --PLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNI-QQALQQRILQQQQMKQQIGSPGQP 2273
Query: 609 QQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSS 668
QQ Q S QQ +S+S Q + Q + Q Q + QP
Sbjct: 2274 NPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQP 2333
Query: 669 QPAQSLPSQPLLRSPLPLQQKLLLQQ--MQNQPIAGMGYQVSQQQR---QDQHSVVGQNT 723
P P L + + Q + N + M Q++ R + S+VG T
Sbjct: 2334 SPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTT 2393
Query: 724 G 724
G
Sbjct: 2394 G 2394
Score = 46.2 bits (108), Expect = 2e-04
Identities = 109/517 (21%), Positives = 160/517 (30%), Gaps = 79/517 (15%)
Query: 86 ARKAGKHTKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNG 145
AR T +T + PPPPA PP A+ AA H ++ ++ NS G
Sbjct: 1887 ARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG 1946
Query: 146 GSG-GINGEQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDI- 203
+G G G Q P S + N + S+ Q +P ++P + + +
Sbjct: 1947 RTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQ-WQQAPLPQQQPMPGLPRPVISMQ 2005
Query: 204 -KRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRK---TNTLPSHTHSPGNGLFN 259
+ G + + Q I+ Q + TL +P ++ N L S+ +
Sbjct: 2006 AQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQ 2065
Query: 260 MGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVP 319
K V +PG + G +Q + P PG P LQ L
Sbjct: 2066 RTAKYVANQPG-----MQPQPGLQSQPGMQP-----QPGMH-QQPSLQNL---------- 2104
Query: 320 PMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLT---QGP 376
Q PRP +P ++ + G P
Sbjct: 2105 --------------------------NAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNP 2138
Query: 377 SGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQ-Q 435
+P + + + L Q Q Q Q GS + H Q Q
Sbjct: 2139 GHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGM----AGGMAGHGQFQ 2194
Query: 436 LKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGP--------SPGPFGQEKIPSPSFGQ 487
Q + QQ QQH P S++ A PG G + P+
Sbjct: 2195 QPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPG-LGADSTPNIQQAL 2253
Query: 488 QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHP 547
Q Q M G GQ M+ + Q HL QQ LS + +P P
Sbjct: 2254 QQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLP--GQQIATSLSNQ-VRSPAP 2310
Query: 548 AMEPRQGNTKPLFHFNSDQANQQMPS---VLPSQNKP 581
PR + P H + Q PS V P P
Sbjct: 2311 VQSPRPQSQPP--HSSPSPRIQPQPSPHHVSPQTGSP 2345
Score = 41.6 bits (96), Expect = 0.004
Identities = 113/488 (23%), Positives = 161/488 (32%), Gaps = 66/488 (13%)
Query: 604 QQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663
+QQQ Q + QQ Q +++ + + QQS S QQ Q Q Q Q
Sbjct: 1813 RQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQ 1872
Query: 664 QQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQM-------QNQPIAGMGYQVSQQQRQDQH 716
P S PS + P + Q+ Q P A + +++ Q Q
Sbjct: 1873 PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQ 1932
Query: 717 SVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQ 776
+ N S P TG G SQ + ++ + Q + +M QQ
Sbjct: 1933 HLYRVNINNSMPPG-----RTGMGTPGSQMAPVSLNVPRPNQ-VSGPVMPSMPPGQWQQA 1986
Query: 777 MLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNS-NQALANP 835
L PQ Q L RP + Q G P+ Q S +L + L +P
Sbjct: 1987 PL-------PQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSP 2039
Query: 836 VSTH------TILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQ 889
S IL N L++ R TA G P QP S Q
Sbjct: 2040 SSPQQQQQVLNILKSNPQLMAAFIKQR-----TAKYVANQPGMQP--QPGLQSQPGMQPQ 2092
Query: 890 LTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQ-LRPNLTHSMASMP 948
+ P N +PR P + P A G G + + P +MASM
Sbjct: 2093 PGMHQQPSLQNLNAMQAGVPR-PGVPPQQQ---AMGGLNPQGQALNIMNPGHNPNMASMN 2148
Query: 949 PQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGV-------------RFPTGTPAAYT 995
PQ ++ Q+ +QQ+ SAG+ + P G P A
Sbjct: 2149 PQ-YREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQ 2207
Query: 996 PNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGP-----LRGLNLR 1050
Q +QQ + Q S + A QM + QM Q G P L+ L+
Sbjct: 2208 QQQRMQQHLPLQGSSMGQM--------AAQMGQLGQMGQPGLGADSTPNIQQALQQRILQ 2259
Query: 1051 PNQLSTQI 1058
Q+ QI
Sbjct: 2260 QQQMKQQI 2267
Score = 41.6 bits (96), Expect = 0.004
Identities = 120/550 (21%), Positives = 185/550 (33%), Gaps = 73/550 (13%)
Query: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
QQQ Q + QQ Q +++ + QQ +S QQ S+ Q Q Q
Sbjct: 1814 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQP 1873
Query: 648 QQQQQQQQQQQQQQQQQQPSS----QPAQSLPSQPLLRSPLPLQ----QKLLLQQMQNQP 699
+ Q P++ +P +P+ P P P +++ + Q Q
Sbjct: 1874 SPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQH 1933
Query: 700 IAGMGYQVSQQQRQDQHSVVGQNTGPS----PSPNPCSNPNTGSGYMNS-QQSLLNQQLM 754
+ + S + G P P PN S P S QQ+ L QQ
Sbjct: 1934 LYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQ- 1992
Query: 755 GKKQTLQRQIMEQKQQLLLQQQMLADAE---KIAP---QDQINRHLSRPPPDYKDQRRNV 808
L R ++ + Q + + + I+P QD + S P + Q N+
Sbjct: 1993 -PMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNI 2051
Query: 809 GNMQP----------TAQY----SGGSSTISLNSNQALANPVSTHTILTPN-SSLLSTSH 853
P TA+Y G L S + H P+ +L +
Sbjct: 2052 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQ--QPSLQNLNAMQA 2109
Query: 854 GTRMPSLSTAVQNMGMYG------NL--PCNQPNTYSVTSGMNQLTQQRNPKQLLANQNN 905
G P + Q MG N+ P + PN S MN ++ +QLL Q
Sbjct: 2110 GVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMAS----MNPQYREMLRRQLLQQQQQ 2165
Query: 906 PMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPN 965
+ + G G QQ + + A QR + ++
Sbjct: 2166 QQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQ 2225
Query: 966 WASQEGTSKQQEALTSAGVRFPTGTPAAYTPN--QSLQQAVGSQQFSQRAVAPPNQLTPA 1023
A+Q G G G A TPN Q+LQQ + QQ ++ + P
Sbjct: 2226 MAAQMG---------QLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPG----- 2271
Query: 1024 VQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLT 1083
Q PM+ L+GQ + +L Q++T L N +S + QS +QPP +
Sbjct: 2272 -QPNPMSPQQHMLSGQP----QASHLPGQQIATS-LSNQVRSPAPV-QSPRPQSQPPHSS 2324
Query: 1084 PSNFPSPNQS 1093
PS P S
Sbjct: 2325 PSPRIQPQPS 2334
Score = 37.4 bits (85), Expect = 0.083
Identities = 74/381 (19%), Positives = 115/381 (30%), Gaps = 44/381 (11%)
Query: 405 PSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSAL 464
P +PQ+Q S + Q ++ Q + + P N S
Sbjct: 655 PVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQ 714
Query: 465 PSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAG------ 518
+S G PG SP P P G+ + +MA ++
Sbjct: 715 MNSMGSVPG--------------MAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQ 760
Query: 519 -PSAQGGHLDVLMQQKPQDLSRS-------FINNPHPAMEPRQGNTKPLFHFNSDQANQQ 570
PS+ G + V M Q P S + NP + P Q + P +
Sbjct: 761 FPSSSGA-MSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGP-QASQLPCPPVTQSPLHPT 818
Query: 571 MPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQ 630
P + PSL H T Q Q Q S+ Q
Sbjct: 819 PPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTP 878
Query: 631 QQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKL 690
Q++ AQ Q Q Q Q QQQ +QP P PL ++ + ++
Sbjct: 879 TVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP----PGTPLSQAAASIDNRV 934
Query: 691 LLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLN 750
P + + + QQ V+ T + P+ G + ++
Sbjct: 935 ------PTPSSVASAETNSQQPGPDVPVLEMKTETQAED---TEPDPGESKGEPRSEMME 985
Query: 751 QQLMGKKQTLQR-QIMEQKQQ 770
+ L G Q + I EQK +
Sbjct: 986 EDLQGASQVKEETDIAEQKSE 1006
Score = 34.3 bits (77), Expect = 0.70
Identities = 34/150 (22%), Positives = 57/150 (38%), Gaps = 6/150 (4%)
Query: 895 NPKQLLANQNNPMMPRPPTLGPSNNNNV-ATFGAGSVGNSQQLRPNLTHSMASMPPQRTS 953
NP +L Q + + P T P + A+ AG P +T + P Q ++
Sbjct: 793 NPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPST 852
Query: 954 NVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRA 1013
V + T P S ++ Q T TP TP Q +V + Q SQ+
Sbjct: 853 PVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQ--PPSVATPQSSQQQ 910
Query: 1014 VAPPNQLTPAVQMRPMNQMSQTLNGQTMGP 1043
P + P P++Q + +++ + P
Sbjct: 911 PTPVHAQPPGT---PLSQAAASIDNRVPTP 937
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 87.4 bits (215), Expect = 7e-17
Identities = 139/535 (25%), Positives = 193/535 (36%), Gaps = 134/535 (25%)
Query: 349 QRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVP 408
Q+S P P+ + +P Q P+ PQ P S PA +++ + P +V
Sbjct: 1879 QQSLPSPTSAPPGTPTQQPSTPQTPQPPA-QPQPSPVSMSPA---GFPSVARTQPPTTVS 1934
Query: 409 QSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSA 468
+ Q + A P V A+Q+++ A +Q R+ + P S
Sbjct: 1935 TGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQ 1994
Query: 469 G-------PSPGPFGQEKIPS--PSFGQQTFSPQSSPMPG-------------VAGG--- 503
P P +PS P QQ PQ PMPG VAG
Sbjct: 1995 MAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMP 2054
Query: 504 ----------SGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFI---------NN 544
S ++ + P Q L++L + PQ L +FI N
Sbjct: 2055 SVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL-KSNPQ-LMAAFIKQRTAKYVANQ 2112
Query: 545 P----------HPAMEPRQG--NTKPLFHFNSDQANQQMPSVLPSQ-------------- 578
P P M+P+ G L + N+ QA P V P Q
Sbjct: 2113 PGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALN 2172
Query: 579 -----NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---------------Q 618
+ P++ Q ++ ++Q QQQQQQQQQQQQQQQQQQ Q
Sbjct: 2173 IMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQ 2232
Query: 619 QQQS------SISAQQQQQQ----QSSISAQQQQQQQQ-----------------QQQQQ 651
Q Q ++ QQ+ QQ Q S Q Q Q QQ Q
Sbjct: 2233 QPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQ 2292
Query: 652 QQQQQQQQQQQQQQPSSQPAQSLPSQPLLR-----SPLPLQQKLLLQQMQNQPIAGMGYQ 706
Q+ QQQQ +QQ QP P Q +L S LP QQ + + NQ + Q
Sbjct: 2293 QRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQ--IATSLSNQVRSPAPVQ 2350
Query: 707 VSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGS---GYMNSQQSLLNQQLMGKKQ 758
+ Q Q HS P PSP+ S P TGS G + S ++Q +G +
Sbjct: 2351 SPRPQSQPPHSSPSPRIQPQPSPHHVS-PQTGSPHPGLAVTMASSIDQGHLGNPE 2404
Score = 47.4 bits (111), Expect = 8e-05
Identities = 81/361 (22%), Positives = 115/361 (31%), Gaps = 53/361 (14%)
Query: 370 PGLTQGPSGSPQLRPPSAGPAFSMAN-SALSTSSPIPSVPQSQAQPQTGSGASRALPSWQ 428
PGL P PQ P S+ N +A+ P P VP Q Q G +
Sbjct: 2119 PGLQSQPGMQPQ---PGMHQQPSLQNLNAMQAGVPRPGVPPQQ-QAMGGLNPQGQALNIM 2174
Query: 429 EVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQ 488
H + + ++ R Q QQQ Q QQ
Sbjct: 2175 NPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQ-------------------------QQ 2209
Query: 489 TFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPA 548
Q G+AGG MA + P GG+ + QQ+
Sbjct: 2210 QQQQQQQGSAGMAGG------MAGHGQFQQPQGPGGYPPAMQQQQRMQQHL--------- 2254
Query: 549 MEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQ 608
P QG++ Q Q L + + P++ QQ+ QQQQ +QQ Q
Sbjct: 2255 --PLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNI-QQALQQRILQQQQMKQQIGSPGQP 2311
Query: 609 QQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSS 668
QQ Q S QQ +S+S Q + Q + Q Q + QP
Sbjct: 2312 NPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQP 2371
Query: 669 QPAQSLPSQPLLRSPLPLQQKLLLQQ--MQNQPIAGMGYQVSQQQR---QDQHSVVGQNT 723
P P L + + Q + N + M Q++ R + S+VG T
Sbjct: 2372 SPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTT 2431
Query: 724 G 724
G
Sbjct: 2432 G 2432
Score = 46.2 bits (108), Expect = 2e-04
Identities = 109/517 (21%), Positives = 160/517 (30%), Gaps = 79/517 (15%)
Query: 86 ARKAGKHTKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNG 145
AR T +T + PPPPA PP A+ AA H ++ ++ NS G
Sbjct: 1925 ARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG 1984
Query: 146 GSG-GINGEQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDI- 203
+G G G Q P S + N + S+ Q +P ++P + + +
Sbjct: 1985 RTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQ-WQQAPLPQQQPMPGLPRPVISMQ 2043
Query: 204 -KRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRK---TNTLPSHTHSPGNGLFN 259
+ G + + Q I+ Q + TL +P ++ N L S+ +
Sbjct: 2044 AQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQ 2103
Query: 260 MGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVP 319
K V +PG + G +Q + P PG P LQ L
Sbjct: 2104 RTAKYVANQPG-----MQPQPGLQSQPGMQP-----QPGMH-QQPSLQNL---------- 2142
Query: 320 PMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLT---QGP 376
Q PRP +P ++ + G P
Sbjct: 2143 --------------------------NAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNP 2176
Query: 377 SGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQ-Q 435
+P + + + L Q Q Q Q GS + H Q Q
Sbjct: 2177 GHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGM----AGGMAGHGQFQ 2232
Query: 436 LKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGP--------SPGPFGQEKIPSPSFGQ 487
Q + QQ QQH P S++ A PG G + P+
Sbjct: 2233 QPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPG-LGADSTPNIQQAL 2291
Query: 488 QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHP 547
Q Q M G GQ M+ + Q HL QQ LS + +P P
Sbjct: 2292 QQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLP--GQQIATSLSNQ-VRSPAP 2348
Query: 548 AMEPRQGNTKPLFHFNSDQANQQMPS---VLPSQNKP 581
PR + P H + Q PS V P P
Sbjct: 2349 VQSPRPQSQPP--HSSPSPRIQPQPSPHHVSPQTGSP 2383
Score = 41.6 bits (96), Expect = 0.004
Identities = 113/488 (23%), Positives = 161/488 (32%), Gaps = 66/488 (13%)
Query: 604 QQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663
+QQQ Q + QQ Q +++ + + QQS S QQ Q Q Q Q
Sbjct: 1851 RQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQ 1910
Query: 664 QQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQM-------QNQPIAGMGYQVSQQQRQDQH 716
P S PS + P + Q+ Q P A + +++ Q Q
Sbjct: 1911 PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQ 1970
Query: 717 SVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQ 776
+ N S P TG G SQ + ++ + Q + +M QQ
Sbjct: 1971 HLYRVNINNSMPPG-----RTGMGTPGSQMAPVSLNVPRPNQ-VSGPVMPSMPPGQWQQA 2024
Query: 777 MLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNS-NQALANP 835
L PQ Q L RP + Q G P+ Q S +L + L +P
Sbjct: 2025 PL-------PQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSP 2077
Query: 836 VSTH------TILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQ 889
S IL N L++ R TA G P QP S Q
Sbjct: 2078 SSPQQQQQVLNILKSNPQLMAAFIKQR-----TAKYVANQPGMQP--QPGLQSQPGMQPQ 2130
Query: 890 LTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQ-LRPNLTHSMASMP 948
+ P N +PR P + P A G G + + P +MASM
Sbjct: 2131 PGMHQQPSLQNLNAMQAGVPR-PGVPPQQQ---AMGGLNPQGQALNIMNPGHNPNMASMN 2186
Query: 949 PQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGV-------------RFPTGTPAAYT 995
PQ ++ Q+ +QQ+ SAG+ + P G P A
Sbjct: 2187 PQ-YREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQ 2245
Query: 996 PNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGP-----LRGLNLR 1050
Q +QQ + Q S + A QM + QM Q G P L+ L+
Sbjct: 2246 QQQRMQQHLPLQGSSMGQM--------AAQMGQLGQMGQPGLGADSTPNIQQALQQRILQ 2297
Query: 1051 PNQLSTQI 1058
Q+ QI
Sbjct: 2298 QQQMKQQI 2305
Score = 41.6 bits (96), Expect = 0.004
Identities = 120/550 (21%), Positives = 185/550 (33%), Gaps = 73/550 (13%)
Query: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
QQQ Q + QQ Q +++ + QQ +S QQ S+ Q Q Q
Sbjct: 1852 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQP 1911
Query: 648 QQQQQQQQQQQQQQQQQQPSS----QPAQSLPSQPLLRSPLPLQ----QKLLLQQMQNQP 699
+ Q P++ +P +P+ P P P +++ + Q Q
Sbjct: 1912 SPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQH 1971
Query: 700 IAGMGYQVSQQQRQDQHSVVGQNTGPS----PSPNPCSNPNTGSGYMNS-QQSLLNQQLM 754
+ + S + G P P PN S P S QQ+ L QQ
Sbjct: 1972 LYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQ- 2030
Query: 755 GKKQTLQRQIMEQKQQLLLQQQMLADAE---KIAP---QDQINRHLSRPPPDYKDQRRNV 808
L R ++ + Q + + + I+P QD + S P + Q N+
Sbjct: 2031 -PMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNI 2089
Query: 809 GNMQP----------TAQY----SGGSSTISLNSNQALANPVSTHTILTPN-SSLLSTSH 853
P TA+Y G L S + H P+ +L +
Sbjct: 2090 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQ--QPSLQNLNAMQA 2147
Query: 854 GTRMPSLSTAVQNMGMYG------NL--PCNQPNTYSVTSGMNQLTQQRNPKQLLANQNN 905
G P + Q MG N+ P + PN S MN ++ +QLL Q
Sbjct: 2148 GVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMAS----MNPQYREMLRRQLLQQQQQ 2203
Query: 906 PMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPN 965
+ + G G QQ + + A QR + ++
Sbjct: 2204 QQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQ 2263
Query: 966 WASQEGTSKQQEALTSAGVRFPTGTPAAYTPN--QSLQQAVGSQQFSQRAVAPPNQLTPA 1023
A+Q G G G A TPN Q+LQQ + QQ ++ + P
Sbjct: 2264 MAAQMG---------QLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPG----- 2309
Query: 1024 VQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLT 1083
Q PM+ L+GQ + +L Q++T L N +S + QS +QPP +
Sbjct: 2310 -QPNPMSPQQHMLSGQP----QASHLPGQQIATS-LSNQVRSPAPV-QSPRPQSQPPHSS 2362
Query: 1084 PSNFPSPNQS 1093
PS P S
Sbjct: 2363 PSPRIQPQPS 2372
Score = 37.4 bits (85), Expect = 0.083
Identities = 74/381 (19%), Positives = 115/381 (30%), Gaps = 44/381 (11%)
Query: 405 PSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSAL 464
P +PQ+Q S + Q ++ Q + + P N S
Sbjct: 693 PVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQ 752
Query: 465 PSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAG------ 518
+S G PG SP P P G+ + +MA ++
Sbjct: 753 MNSMGSVPG--------------MAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQ 798
Query: 519 -PSAQGGHLDVLMQQKPQDLSRS-------FINNPHPAMEPRQGNTKPLFHFNSDQANQQ 570
PS+ G + V M Q P S + NP + P Q + P +
Sbjct: 799 FPSSSGA-MSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGP-QASQLPCPPVTQSPLHPT 856
Query: 571 MPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQ 630
P + PSL H T Q Q Q S+ Q
Sbjct: 857 PPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTP 916
Query: 631 QQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKL 690
Q++ AQ Q Q Q Q QQQ +QP P PL ++ + ++
Sbjct: 917 TVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP----PGTPLSQAAASIDNRV 972
Query: 691 LLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLN 750
P + + + QQ V+ T + P+ G + ++
Sbjct: 973 ------PTPSSVASAETNSQQPGPDVPVLEMKTETQAED---TEPDPGESKGEPRSEMME 1023
Query: 751 QQLMGKKQTLQR-QIMEQKQQ 770
+ L G Q + I EQK +
Sbjct: 1024 EDLQGASQVKEETDIAEQKSE 1044
Score = 34.3 bits (77), Expect = 0.70
Identities = 34/150 (22%), Positives = 57/150 (38%), Gaps = 6/150 (4%)
Query: 895 NPKQLLANQNNPMMPRPPTLGPSNNNNV-ATFGAGSVGNSQQLRPNLTHSMASMPPQRTS 953
NP +L Q + + P T P + A+ AG P +T + P Q ++
Sbjct: 831 NPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPST 890
Query: 954 NVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRA 1013
V + T P S ++ Q T TP TP Q +V + Q SQ+
Sbjct: 891 PVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQ--PPSVATPQSSQQQ 948
Query: 1014 VAPPNQLTPAVQMRPMNQMSQTLNGQTMGP 1043
P + P P++Q + +++ + P
Sbjct: 949 PTPVHAQPPGT---PLSQAAASIDNRVPTP 975
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 87.0 bits (214), Expect = 9e-17
Identities = 92/276 (33%), Positives = 118/276 (42%), Gaps = 47/276 (17%)
Query: 517 AGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLP 576
AG S Q G L + Q KPQ + P P + +Q P QQ PS
Sbjct: 403 AGSSNQPGLLASVPQPKPQAPP----SQPLPQTQAKQPQAPP--------TPQQTPST-Q 449
Query: 577 SQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQ------QQQQQQQQQQSSISAQQQQ 630
+Q P+ T Q QQQ +QQQQQQQ QQQ QQQQ Q QQ ++ QQ
Sbjct: 450 AQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQ 509
Query: 631 Q---QQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ 687
Q +S QQQ Q QQQQQQQQQQQQQQ A +L Q L+ LQ
Sbjct: 510 PAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQL-----ATALHQQQLMTQQAALQ 564
Query: 688 QKLLL---QQMQNQPIAGMGYQVSQQ-------------QRQDQHSVVGQNTGPSPSPNP 731
QK + QQ Q QP A +Q+ Q +V GQ G S P
Sbjct: 565 QKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVG---SLTP 621
Query: 732 CSNPNT-GSGYMNSQQSLLNQQLMGKKQTLQRQIME 766
S+P T +G+ + + + G + Q+++
Sbjct: 622 PSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQ 657
Score = 68.6 bits (166), Expect = 3e-11
Identities = 97/359 (27%), Positives = 135/359 (37%), Gaps = 59/359 (16%)
Query: 534 PQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQ 593
P+ ++ P+P + P Q P Q P S N+P LL Q + Q
Sbjct: 366 PRQRPKAGQTQPNPGILPIQPALTP----RKRATVQPPPQAAGSSNQPGLLASVPQPKPQ 421
Query: 594 QQQQQQQQQQQQQQQQ-----QQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQ 648
Q Q Q +Q Q QQ Q Q + A Q QQQ + +QQQQQQ
Sbjct: 422 APPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFL-----KQQQQQQ 476
Query: 649 QQQQQQQ-------QQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIA 701
Q QQ QQQQ Q QQ + PA P+ + + P+ Q Q MQN
Sbjct: 477 QPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPA--IAQFPVVSQGGSQQQLMQN---- 530
Query: 702 GMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQ 761
YQ QQQ+Q Q Q + ++ QQ + Q + +K T+
Sbjct: 531 --FYQQQQQQQQQQQQ---QQLATA---------------LHQQQLMTQQAALQQKPTMA 570
Query: 762 RQIMEQKQQLLLQQQMLADAEKI-APQDQINRHLSRPPPDYKDQRRNVGNM----QPTAQ 816
Q Q Q A I AP Q + + PPP + Q+ VG++ P Q
Sbjct: 571 AGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQK--VGSLTPPSSPKTQ 628
Query: 817 YSGGSSTISLNSNQALAN-PVSTHTIL----TPNSSLLSTSHGTRMPSLSTAVQNMGMY 870
+G +S ++ A+ P S T L +SL + T PS S +Y
Sbjct: 629 RAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVY 687
Score = 55.1 bits (131), Expect = 4e-07
Identities = 88/389 (22%), Positives = 131/389 (33%), Gaps = 94/389 (24%)
Query: 370 PGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQE 429
P LT + Q PP A + + S P P P SQ PQT + +A P+ Q+
Sbjct: 386 PALTPRKRATVQ-PPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQ 444
Query: 430 V--SHAQQL---KQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPS 484
+ AQ L Q QQ ++Q QQQ QP P+ P+ + Q++ +
Sbjct: 445 TPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPP-----PAQQQPAGTFYQQQQAQTQQ 499
Query: 485 F---GQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSF 541
F T P + P V+ G Q ++M N+ QQ+ Q
Sbjct: 500 FQAVHPATQQPAIAQFPVVSQGGSQQQLMQNF---------------YQQQQQQ------ 538
Query: 542 INNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQ 601
Q QQ+ + L QQQ
Sbjct: 539 ---------------------QQQQQQQQLATAL-------------------HQQQLMT 558
Query: 602 QQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQ 661
QQ QQ+ QQ Q Q + + Q Q+ +I A +QQ + Q Q Q+
Sbjct: 559 QQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQA-PVRQQPKVQTTPPPAVQGQKVG 617
Query: 662 QQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQ 721
PSS Q + +L + + + G+ S Q Q +
Sbjct: 618 SLTPPSSPKTQR------------AGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASL 665
Query: 722 NTGPSPSPNPCSNPNTGSGYMNSQQSLLN 750
N S + P +P T SQQ++ N
Sbjct: 666 NKSKSATTTPSGSPRT------SQQNVYN 688
>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
Length = 2245
Score = 86.7 bits (213), Expect = 1e-16
Identities = 147/658 (22%), Positives = 245/658 (37%), Gaps = 139/658 (21%)
Query: 127 PPDYHHH-HQQHLLNSSNNGGSGGINGEQ--QPPASTPGDQRNSALIALQGSLKRKQVVN 183
PP +H Q ++N S ING Q P +++ G R+ ++ ++ R+ V +
Sbjct: 1061 PPQHHSCLPDQEVINGSL------INGRQADSPMSTSSGSSRSFSVASMLPETTREDVTS 1114
Query: 184 LSPANSKRPNGFVDNS---FLDIKRIRVGENLSAGQGGLQIN-------NGQSQIMSGTL 233
+ N+ FV+ + L + I ENL G+ GLQ + ++ ++ G
Sbjct: 1115 NATTNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQADIREVASKPSEASLLEGDP 1174
Query: 234 PM-SQAPLR----KTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENI 288
P SQ P + P+ +S G+ ++ + P E SCS
Sbjct: 1175 PFKSQIPKESGTGQAEATPNEFNSQGS------IEATMERPLEKPSCSL----------- 1217
Query: 289 FPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQS 348
G + + LQ+ ++ P ++ L + N+I+ QS
Sbjct: 1218 ---------GIKTSNASLQDSTSQ-----PPSITSLSVNNLIH---------------QS 1248
Query: 349 QRSTPRPSLP-----MEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSP 403
S P S E+ + + + ++ GS +PP GP+ S ++
Sbjct: 1249 SISHPLASCAGLSPTSEQTTVPATVNLTVSSSSYGS---QPP--GPSLMTEYSQEQLNTM 1303
Query: 404 IPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSA 463
++P SQ Q + + + + L +A RQ+H +
Sbjct: 1304 TSTIPNSQIQEPLLKPSHESRKDSAKRAVQDDLLLSSAKRQKHCQ--------------- 1348
Query: 464 LPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQG 523
P P E + S T S Q+ M S++ N P +
Sbjct: 1349 --------PAPLRLESMSLMSRTPDTISDQTQMMV--------SQIPPNSSNSVVPVSNP 1392
Query: 524 GHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSV---LPSQNK 580
H D L + P S +F+ E + G+ + QA+Q + ++ +P+Q
Sbjct: 1393 AHGDGLTRLFPP--SNNFVTPALRQTEVQCGSQPSVAEQQQTQASQHLQALQQHVPAQGV 1450
Query: 581 PSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQ 640
L +QQQQQQQQQQQQQQQQQ Q +++ Q + S
Sbjct: 1451 SHLHSNHLYIKQQQQQQQQQQQQQQQQQAGQLRERHHLYQMQHHVPHAESSVHSQPHNVH 1510
Query: 641 QQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPI 700
QQ+ QQ+ Q Q+++ Q Q Q S QP Q ++ P QQMQ Q
Sbjct: 1511 QQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTDQSRSKTGQPHPHH---QQMQQQ-- 1565
Query: 701 AGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQ 758
+ Q+ G S + C NP+T + N Q+ LNQ +M ++Q
Sbjct: 1566 ------------------MQQHFGSSQTEKSCENPSTSRNHHNHPQNHLNQDIMHQQQ 1605
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 85.1 bits (209), Expect = 3e-16
Identities = 71/234 (30%), Positives = 99/234 (42%), Gaps = 31/234 (13%)
Query: 585 HYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQ 644
H+ +QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ ++ Q Q Q + S Q +
Sbjct: 2713 HFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAV 2772
Query: 645 QQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAG-- 702
+ + + Q+Q+ Q QP AQS P QP + + Q Q Q +
Sbjct: 2773 GKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPR 2832
Query: 703 ----------MGYQVSQQQRQDQHSVVGQNTGPSPSPNPC-----------------SNP 735
QV++ R + Q + +P P S+P
Sbjct: 2833 PGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSP 2892
Query: 736 NTGSGYMN--SQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQ 787
+ MN + Q QT+ Q + +Q L L+QQ + + I PQ
Sbjct: 2893 GVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQ 2946
Score = 47.4 bits (111), Expect = 8e-05
Identities = 67/324 (20%), Positives = 117/324 (36%), Gaps = 24/324 (7%)
Query: 531 QQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQ 590
QQ+ Q + + +Q T Q Q P+ + + K + H + Q
Sbjct: 2725 QQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQ 2784
Query: 591 QQQQQQ-------QQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQ 643
+Q+ Q Q Q Q Q Q Q Q QQQ ++ + + ++
Sbjct: 2785 KQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVAN 2844
Query: 644 QQQQQQQQQQQQQQQQQQQQQQPSSQPAQ-SLPSQPLLRSPLPLQQKLLLQQMQNQPIAG 702
Q + + Q Q Q Q Q + QPAQ +L P++ P + + + +AG
Sbjct: 2845 LQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLP-MNVAG 2903
Query: 703 MGYQVSQQQRQDQHSVVGQNT---------GPSPSPNPCSNPNTGSGYMNSQQSLLNQQL 753
+ + Q Q+ +VV Q + P G QQ + QQ+
Sbjct: 2904 ISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQI 2963
Query: 754 MGKKQTLQRQIMEQKQQLLLQQQM---LADAEKIAPQDQINRHLS-RPPPDYKDQRRNVG 809
Q+++ Q L Q + ++ A+K+A Q+ + P Q+ V
Sbjct: 2964 --TTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVA 3021
Query: 810 NMQPTAQYSGGSSTISLNSNQALA 833
++Q A S +S ++ QA A
Sbjct: 3022 SIQQVASASQQASPQTVALTQATA 3045
Score = 46.6 bits (109), Expect = 1e-04
Identities = 135/631 (21%), Positives = 204/631 (32%), Gaps = 83/631 (13%)
Query: 105 PPPPPAAPPAA---SQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTP 161
PPPPP PP QAA + P PP Q Q P + P
Sbjct: 2513 PPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQP--------VQAPAKAQP 2564
Query: 162 GDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQI 221
+ L G++K S + P G V + + N AG
Sbjct: 2565 AITTGGSAAVLAGTIKT------SVTGTSMPTGAVSGNVI--------VNTIAGVPAATF 2610
Query: 222 NNGQSQIMSG------TLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSC 275
+ ++ S T P AP + +T P L + G
Sbjct: 2611 QSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVT 2670
Query: 276 SKHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIK 335
S +T N+ P + P L+ P++ ++ T + +P + + +
Sbjct: 2671 SVTASAVVTT-NLTPVQ---TPARSLV-PQV----SQATGVQLPGKTITPAHFQLLRQQQ 2721
Query: 336 QDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSP-------QLRPPSAG 388
Q QQ Q+ + ++ S+ QG + SP +L P
Sbjct: 2722 QQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHL- 2780
Query: 389 PAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQH-- 446
M L P P PQ+Q+ P + + S + QL + A R
Sbjct: 2781 --IKMQKQKLQMP-PQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALL 2837
Query: 447 -----ARMQQHQQQHQPTNW---SALPSSAGPSPGPFGQEKIPSPSFGQQTFS-PQSSPM 497
A +Q + PT+ + P P K P S S P + +
Sbjct: 2838 TGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTL 2897
Query: 498 P----GVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQ 553
P G++ GQ + A A P H+ L++ K Q + + P A P
Sbjct: 2898 PMNVAGISVAIGQPQKAAGQTVVAQPV----HMQQLLKLKQQAVQQQKAIQPQAAQGPAA 2953
Query: 554 GNTKPLFHFNSDQANQQMPS-----VLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQ 608
K + QQ + L +Q + + Q+ QQ Q Q Q + Q
Sbjct: 2954 VQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQV 3013
Query: 609 QQQQQQQQQQQQQSSISAQQQQQQ----QSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQ 664
QQQ QQ +S S Q Q Q++ + QQ Q Q QQ+ QQQ
Sbjct: 3014 VQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVV 3073
Query: 665 QPSSQPAQS----LPSQPLLRSPLPLQQKLL 691
+S P Q+ P+Q S P QQ L
Sbjct: 3074 TTASAPLQTPGAPNPAQVPASSDSPSQQPKL 3104
Score = 40.8 bits (94), Expect = 0.008
Identities = 103/448 (22%), Positives = 149/448 (33%), Gaps = 100/448 (22%)
Query: 392 SMANSALSTSSPIP-SVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQ 450
S+ SA+ T++ P P PQ LP QL + +QQ + Q
Sbjct: 2671 SVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQ 2730
Query: 451 QHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVM 510
Q QQQ Q++ QQT + +P + G QS
Sbjct: 2731 QQQQQ---------------------QQQQQQQQQQQQTTTTSQVQVPQIQ-GQAQSPAQ 2768
Query: 511 ANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQ 570
+ K P HL + +QK Q + P P + + Q QQ
Sbjct: 2769 IKAVGKLTPE----HLIKMQKQKLQMPPQP----PPPQAQSAPPQPTAQVQVQTSQPPQQ 2820
Query: 571 MPSVLPSQNKP--------------SLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQ-- 614
L + P + T+ Q Q Q Q Q Q Q Q +
Sbjct: 2821 QSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPP 2880
Query: 615 -----------------------------QQQQQQQSSISAQQQQQQQSSISAQQQQQQQ 645
Q Q+ ++ AQ QQ QQ QQQ
Sbjct: 2881 VVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQ 2940
Query: 646 QQQQQQQQQ-----QQQQQQQQQQQPSSQPAQSLPSQPLLR-----SPLPLQQKLL-LQQ 694
+ Q Q Q QQ+ QQ P +Q + +QP L+ +P+ QKL QQ
Sbjct: 2941 KAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQ 3000
Query: 695 MQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQL- 753
+Q Q QV QQ Q + + Q S +P + T Q + QQ+
Sbjct: 3001 VQTQIQVAKLPQVVQQ--QTPVASIQQVASASQQASPQTVALT-------QATAAGQQVQ 3051
Query: 754 MGKKQTLQRQIMEQKQQLLLQQQMLADA 781
M T Q+++QK L+QQQ++ A
Sbjct: 3052 MIPAVTATAQVVQQK---LIQQQVVTTA 3076
Score = 40.8 bits (94), Expect = 0.008
Identities = 89/383 (23%), Positives = 139/383 (36%), Gaps = 53/383 (13%)
Query: 409 QSQAQPQTGSGASRALPSWQ-EVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSS 467
Q Q Q QT + + +P Q + Q+K + +H Q Q+ P P +
Sbjct: 2741 QQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQ-PPPPQA 2799
Query: 468 AGPSPGPFGQEKIPSPSFGQQTFSPQ----SSPMPG-VAGGSGQSKVMANYMYKAGPSAQ 522
P P Q ++ + QQ SPQ ++P PG + G+ + + + + P++Q
Sbjct: 2800 QSAPPQPTAQVQVQTSQPPQQQ-SPQLTTVTAPRPGALLTGTTVANLQVARLTRV-PTSQ 2857
Query: 523 GGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPS 582
+ Q PQ + P ++ ++ + + A + P +
Sbjct: 2858 LQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKA--- 2914
Query: 583 LLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQ----------QQQ 632
Q Q QQ + +QQ QQQ+ Q Q Q + QQ+ QQ
Sbjct: 2915 ----AGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQ 2970
Query: 633 QSSISAQQQQQQQ---------------QQQQQQQQQQQQQQQQQQQQP--SSQPAQSLP 675
+ + +AQ + Q QQ Q Q Q + Q QQQ P S Q S
Sbjct: 2971 KVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASAS 3030
Query: 676 SQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSP-----SPN 730
Q ++ Q QQ+Q P QV QQ+ Q V T +P +PN
Sbjct: 3031 QQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVV---TTASAPLQTPGAPN 3087
Query: 731 PCSNPNTGSGYMNSQQSLLNQQL 753
P P S SQQ L ++
Sbjct: 3088 PAQVP--ASSDSPSQQPKLQMRV 3108
Score = 34.7 bits (78), Expect = 0.54
Identities = 23/81 (28%), Positives = 36/81 (44%)
Query: 620 QQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPL 679
Q +S+ A++ +++ +++ QQ+ QQ Q Q Q QQ P Q+ SQP
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPP 2535
Query: 680 LRSPLPLQQKLLLQQMQNQPI 700
P Q Q Q QP+
Sbjct: 2536 AGPPAVQPQPQPQPQTQPQPV 2556
Score = 33.9 bits (76), Expect = 0.92
Identities = 43/198 (21%), Positives = 74/198 (37%), Gaps = 20/198 (10%)
Query: 903 QNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTT 962
Q P P P+ T G + + ++ ++T + SMP S +I +
Sbjct: 2546 QPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGT--SMPTGAVSGNVIVNTIA 2603
Query: 963 APNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTP 1022
A+ + +K+ + P A TP S V Q RAV P TP
Sbjct: 2604 GVPAATFQSINKRLAS--------PVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATP 2655
Query: 1023 AVQMRPMNQMSQTLNGQTMGPLRGLNLRPNQL-STQILPNLNQSGTGLNQSRTGINQP-P 1080
+ Q + + T + NL P Q + ++P ++Q+ TG+ P
Sbjct: 2656 DLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQA--------TGVQLPGK 2707
Query: 1081 SLTPSNFPSPNQSSRAFQ 1098
++TP++F Q + Q
Sbjct: 2708 TITPAHFQLLRQQQQQQQ 2725
Score = 32.7 bits (73), Expect = 2.0
Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 5/124 (4%)
Query: 557 KPLFHFNSDQANQQMPSVLPSQ----NKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQ 612
KPL N Q N + SVL +KP L + ++ ++++ QQ+ QQ
Sbjct: 2443 KPLLGMNPFQKNPKHASVLAESGINYDKP-LPPIQVASLRAERIAKEKKALADQQKAQQP 2501
Query: 613 QQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQ 672
Q Q QQ Q Q Q Q Q Q Q Q QP PA+
Sbjct: 2502 AVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAK 2561
Query: 673 SLPS 676
+ P+
Sbjct: 2562 AQPA 2565
Score = 31.6 bits (70), Expect = 4.6
Identities = 39/158 (24%), Positives = 50/158 (31%), Gaps = 18/158 (11%)
Query: 593 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQ---------- 642
QQ Q Q Q Q+Q QQQ S Q +S+ Q
Sbjct: 506 QQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGV 565
Query: 643 -----QQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQN 697
Q QQ Q + Q Q Q + QP +P+ P + P+P Q Q +
Sbjct: 566 PTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQP--AQLALH 623
Query: 698 QPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNP 735
P G QV Q +V P PC P
Sbjct: 624 VPTPGK-VQVQASQLSSLPQMVASTRLPVDPAPPCPRP 660
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 83.6 bits (205), Expect = 1e-15
Identities = 177/713 (24%), Positives = 257/713 (36%), Gaps = 152/713 (21%)
Query: 317 SVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIV------IKSEYSP 370
SV P S+ L N +Q QQ S+ + M++ + I+SE P
Sbjct: 791 SVHPQSENTLSNQQQQQQQQ---------QQVMESSAAMVMEMQQSICQAAAQIQSELFP 841
Query: 371 GLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEV 430
T +G+ Q P + M SALST+ + + + P SG + + Q+V
Sbjct: 842 S-TASANGNLQQSPVYQQTSHMM--SALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQV 898
Query: 431 SH-----------------AQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPG 473
+ Q KQI + Q QH +QP + + S
Sbjct: 899 ATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQ 958
Query: 474 PFGQEKIPSPSFGQQTFSPQSSPMPGVAGGS---GQSKVMANYMYKAGPSAQGGHLDVLM 530
G ++ + F Q + M + G+ S A + P A +L
Sbjct: 959 NSGTQQQGNGLF------QQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLS--- 1009
Query: 531 QQKPQDLSRSFINNPHPAMEPRQGNTK------PLFHFNSDQA---------NQQMPSVL 575
Q+ S ++P+P + + T P+FH S A +QQ ++
Sbjct: 1010 ----QETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIF 1065
Query: 576 PSQ--------------------NKPSLLHYTQQQQQQQQQQQQQ-----QQQQQQQQQQ 610
SQ N S L T +QQ QQQ Q Q+Q
Sbjct: 1066 LSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQA 1125
Query: 611 QQQQQQQQQQQSSISA-------QQQQ----QQQSSISAQQ-----QQQQQQQQQQQQQQ 654
Q QQ Q Q ++ + Q QQ Q Q SI A Q Q+QQQQQQQQQQQQ
Sbjct: 1126 QPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQ 1185
Query: 655 QQQQQQQQQQQPSSQPAQSLPSQPLLRSPL-PLQQKLLLQQMQNQPI-------AGMGYQ 706
QQQQQ ++ + P QP P Q + Q+ QNQ I A M +
Sbjct: 1186 QQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQE 1245
Query: 707 VSQQQRQDQHSVVG-QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIM 765
Q Q Q +V QN GP+ S +SQ L + + Q +Q
Sbjct: 1246 QQPMQFQSQSTVSSLQNPGPTQSE-------------SSQTPLFHSS--PQIQLVQGSPS 1290
Query: 766 EQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVG----NMQPTAQYSGGS 821
Q+QQ+ L L+ A A Q IN+ + P Y Q G P Q +
Sbjct: 1291 SQEQQVTL---FLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFH 1347
Query: 822 STISLNSNQALANPVSTHTI-------LTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLP 874
+T NQ +P S+ + N S L TS +P A+ G N
Sbjct: 1348 NTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNE- 1406
Query: 875 CNQPNTYSVTSGMNQLTQQRNP--KQLLANQNNPMMPRPPTLGPSNNNNVATF 925
QP VT+ ++Q + +P + NQN + +L NN +F
Sbjct: 1407 -GQP---PVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1455
Score = 71.2 bits (173), Expect = 5e-12
Identities = 224/1036 (21%), Positives = 361/1036 (34%), Gaps = 194/1036 (18%)
Query: 232 TLPMSQAPLRKTNTLPSH-----THSP---GNGLFNMGLKEVKKEPGETLSCSKHMDGQM 283
TLP+S TN SH T++P G N+ +K+ P S + M
Sbjct: 441 TLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMK 500
Query: 284 T------QENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIK-- 335
T + NI PN LM P + + +++ ++ + + I T K
Sbjct: 501 TTGCNLDKVNIIPNA--------LMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSV 552
Query: 336 ---QDDPFNID--LGQQSQRSTPRPSLPME----KIVIKSEYSPGLTQGPSGSPQLRPPS 386
Q NI G S S LP E + + Y+P T + + P
Sbjct: 553 GSTQQTLENISNIAGNGSFSSPSSSHLPSENEKQQQIQPKAYNPE-TLTTIQTQDISQPG 611
Query: 387 AGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRA-LPSWQEVSHAQQLKQIAANRQQ 445
PA S A+S L S ++ Q Q QT SR L S V + QL + + +QQ
Sbjct: 612 TFPAVS-ASSQLPNSD---ALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQ 667
Query: 446 HARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSG 505
+Q Q Q + + PS S +++ + SF T S S + V
Sbjct: 668 SPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLE 727
Query: 506 QSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSD 565
+ +++ ++ SA G+ +V +Q D+ + +T+P H D
Sbjct: 728 AQQQLSSVLF----SAPDGNENV-QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPD 782
Query: 566 QANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSIS 625
++LP + + Q + QQQQQQQQQQ + + QQS
Sbjct: 783 -------NLLPGRAES-----VHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQ 830
Query: 626 AQQQQQQQ---SSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS 682
A Q Q + S+ SA QQ QQ + Q + S P+ +
Sbjct: 831 AAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNET 890
Query: 683 PLPLQQKLLL--QQMQNQPIAGMGYQVSQQQRQDQHSVVG-----QNTGPS-PSPNPCSN 734
Q++ M +G G + Q +Q Q+SV Q++G + P N S+
Sbjct: 891 STTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSS 950
Query: 735 PNTGSGYMNS----------QQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKI 784
+ NS QQ N+ + + +Q + QL Q +ADA+ +
Sbjct: 951 TKSMMSVQNSGTQQQGNGLFQQG--NEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNL 1008
Query: 785 APQDQINR-HLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNS-------------NQ 830
+ + Q + H P + + MQP +S + + S +Q
Sbjct: 1009 SQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQ 1068
Query: 831 ALANPVSTHTI------LTPN--SSLLSTSHGTRM--------------PSLS---TAVQ 865
+ N + T+T+ PN S L STS+ + P LS
Sbjct: 1069 SPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPP 1128
Query: 866 NMGMY------GNLPCN--------------------QPNTYSVTSGMNQLTQQRNPKQ- 898
G++ G+LP N Q N+ S Q QQ+ +Q
Sbjct: 1129 QQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQ 1188
Query: 899 ----LLANQN------NPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMP 948
L +NQN +P P P + N N +A N +Q ++ H ++M
Sbjct: 1189 QQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMA--------NQEQQNQSIFHQQSNMA 1240
Query: 949 P--QRTSNVMITSNTTAPNWASQEGTSKQQEAL----TSAGVRFPTGTPAAYTPN----- 997
P Q + S +T + + T + +S ++ G+P++
Sbjct: 1241 PMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFL 1300
Query: 998 -----QSLQQAVGSQQFSQRAVAPPNQLTPAVQ-----MRPMNQMSQTLNGQTMGPLRGL 1047
+LQ ++ Q Q + P P +Q +P + G TM L+
Sbjct: 1301 SPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNS 1360
Query: 1048 NLRPNQLSTQIL----PNLNQSGTG----LNQSRTGINQPPSLTPSNFPSPNQSSRAFQG 1099
Q S L N +Q T L I+QP P N P ++ Q
Sbjct: 1361 PGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQ--PQNEGQPPVTTLLSQQ 1418
Query: 1100 TDHSSDLAFDFLSQQN 1115
+S LA + QN
Sbjct: 1419 MPENSPLASSINTNQN 1434
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 83.6 bits (205), Expect = 1e-15
Identities = 177/713 (24%), Positives = 257/713 (36%), Gaps = 152/713 (21%)
Query: 317 SVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIV------IKSEYSP 370
SV P S+ L N +Q QQ S+ + M++ + I+SE P
Sbjct: 867 SVHPQSENTLSNQQQQQQQQ---------QQVMESSAAMVMEMQQSICQAAAQIQSELFP 917
Query: 371 GLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEV 430
T +G+ Q P + M SALST+ + + + P SG + + Q+V
Sbjct: 918 S-TASANGNLQQSPVYQQTSHMM--SALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQV 974
Query: 431 SH-----------------AQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPG 473
+ Q KQI + Q QH +QP + + S
Sbjct: 975 ATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQ 1034
Query: 474 PFGQEKIPSPSFGQQTFSPQSSPMPGVAGGS---GQSKVMANYMYKAGPSAQGGHLDVLM 530
G ++ + F Q + M + G+ S A + P A +L
Sbjct: 1035 NSGTQQQGNGLF------QQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLS--- 1085
Query: 531 QQKPQDLSRSFINNPHPAMEPRQGNTK------PLFHFNSDQA---------NQQMPSVL 575
Q+ S ++P+P + + T P+FH S A +QQ ++
Sbjct: 1086 ----QETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIF 1141
Query: 576 PSQ--------------------NKPSLLHYTQQQQQQQQQQQQQ-----QQQQQQQQQQ 610
SQ N S L T +QQ QQQ Q Q+Q
Sbjct: 1142 LSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQA 1201
Query: 611 QQQQQQQQQQQSSISA-------QQQQ----QQQSSISAQQ-----QQQQQQQQQQQQQQ 654
Q QQ Q Q ++ + Q QQ Q Q SI A Q Q+QQQQQQQQQQQQ
Sbjct: 1202 QPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQ 1261
Query: 655 QQQQQQQQQQQPSSQPAQSLPSQPLLRSPL-PLQQKLLLQQMQNQPI-------AGMGYQ 706
QQQQQ ++ + P QP P Q + Q+ QNQ I A M +
Sbjct: 1262 QQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQE 1321
Query: 707 VSQQQRQDQHSVVG-QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIM 765
Q Q Q +V QN GP+ S +SQ L + + Q +Q
Sbjct: 1322 QQPMQFQSQSTVSSLQNPGPTQSE-------------SSQTPLFHSS--PQIQLVQGSPS 1366
Query: 766 EQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVG----NMQPTAQYSGGS 821
Q+QQ+ L L+ A A Q IN+ + P Y Q G P Q +
Sbjct: 1367 SQEQQVTL---FLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFH 1423
Query: 822 STISLNSNQALANPVSTHTI-------LTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLP 874
+T NQ +P S+ + N S L TS +P A+ G N
Sbjct: 1424 NTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNE- 1482
Query: 875 CNQPNTYSVTSGMNQLTQQRNP--KQLLANQNNPMMPRPPTLGPSNNNNVATF 925
QP VT+ ++Q + +P + NQN + +L NN +F
Sbjct: 1483 -GQP---PVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1531
Score = 71.2 bits (173), Expect = 5e-12
Identities = 224/1036 (21%), Positives = 361/1036 (34%), Gaps = 194/1036 (18%)
Query: 232 TLPMSQAPLRKTNTLPSH-----THSP---GNGLFNMGLKEVKKEPGETLSCSKHMDGQM 283
TLP+S TN SH T++P G N+ +K+ P S + M
Sbjct: 517 TLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMK 576
Query: 284 T------QENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIK-- 335
T + NI PN LM P + + +++ ++ + + I T K
Sbjct: 577 TTGCNLDKVNIIPNA--------LMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSV 628
Query: 336 ---QDDPFNID--LGQQSQRSTPRPSLPME----KIVIKSEYSPGLTQGPSGSPQLRPPS 386
Q NI G S S LP E + + Y+P T + + P
Sbjct: 629 GSTQQTLENISNIAGNGSFSSPSSSHLPSENEKQQQIQPKAYNPE-TLTTIQTQDISQPG 687
Query: 387 AGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRA-LPSWQEVSHAQQLKQIAANRQQ 445
PA S A+S L S ++ Q Q QT SR L S V + QL + + +QQ
Sbjct: 688 TFPAVS-ASSQLPNSD---ALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQ 743
Query: 446 HARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSG 505
+Q Q Q + + PS S +++ + SF T S S + V
Sbjct: 744 SPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLE 803
Query: 506 QSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSD 565
+ +++ ++ SA G+ +V +Q D+ + +T+P H D
Sbjct: 804 AQQQLSSVLF----SAPDGNENV-QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPD 858
Query: 566 QANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSIS 625
++LP + + Q + QQQQQQQQQQ + + QQS
Sbjct: 859 -------NLLPGRAES-----VHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQ 906
Query: 626 AQQQQQQQ---SSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS 682
A Q Q + S+ SA QQ QQ + Q + S P+ +
Sbjct: 907 AAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNET 966
Query: 683 PLPLQQKLLL--QQMQNQPIAGMGYQVSQQQRQDQHSVVG-----QNTGPS-PSPNPCSN 734
Q++ M +G G + Q +Q Q+SV Q++G + P N S+
Sbjct: 967 STTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSS 1026
Query: 735 PNTGSGYMNS----------QQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKI 784
+ NS QQ N+ + + +Q + QL Q +ADA+ +
Sbjct: 1027 TKSMMSVQNSGTQQQGNGLFQQG--NEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNL 1084
Query: 785 APQDQINR-HLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNS-------------NQ 830
+ + Q + H P + + MQP +S + + S +Q
Sbjct: 1085 SQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQ 1144
Query: 831 ALANPVSTHTI------LTPN--SSLLSTSHGTRM--------------PSLS---TAVQ 865
+ N + T+T+ PN S L STS+ + P LS
Sbjct: 1145 SPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPP 1204
Query: 866 NMGMY------GNLPCN--------------------QPNTYSVTSGMNQLTQQRNPKQ- 898
G++ G+LP N Q N+ S Q QQ+ +Q
Sbjct: 1205 QQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQ 1264
Query: 899 ----LLANQN------NPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMP 948
L +NQN +P P P + N N +A N +Q ++ H ++M
Sbjct: 1265 QQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMA--------NQEQQNQSIFHQQSNMA 1316
Query: 949 P--QRTSNVMITSNTTAPNWASQEGTSKQQEAL----TSAGVRFPTGTPAAYTPN----- 997
P Q + S +T + + T + +S ++ G+P++
Sbjct: 1317 PMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFL 1376
Query: 998 -----QSLQQAVGSQQFSQRAVAPPNQLTPAVQ-----MRPMNQMSQTLNGQTMGPLRGL 1047
+LQ ++ Q Q + P P +Q +P + G TM L+
Sbjct: 1377 SPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNS 1436
Query: 1048 NLRPNQLSTQIL----PNLNQSGTG----LNQSRTGINQPPSLTPSNFPSPNQSSRAFQG 1099
Q S L N +Q T L I+QP P N P ++ Q
Sbjct: 1437 PGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQ--PQNEGQPPVTTLLSQQ 1494
Query: 1100 TDHSSDLAFDFLSQQN 1115
+S LA + QN
Sbjct: 1495 MPENSPLASSINTNQN 1510
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 83.6 bits (205), Expect = 1e-15
Identities = 177/713 (24%), Positives = 257/713 (36%), Gaps = 152/713 (21%)
Query: 317 SVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIV------IKSEYSP 370
SV P S+ L N +Q QQ S+ + M++ + I+SE P
Sbjct: 884 SVHPQSENTLSNQQQQQQQQ---------QQVMESSAAMVMEMQQSICQAAAQIQSELFP 934
Query: 371 GLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEV 430
T +G+ Q P + M SALST+ + + + P SG + + Q+V
Sbjct: 935 S-TASANGNLQQSPVYQQTSHMM--SALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQV 991
Query: 431 SH-----------------AQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPG 473
+ Q KQI + Q QH +QP + + S
Sbjct: 992 ATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQ 1051
Query: 474 PFGQEKIPSPSFGQQTFSPQSSPMPGVAGGS---GQSKVMANYMYKAGPSAQGGHLDVLM 530
G ++ + F Q + M + G+ S A + P A +L
Sbjct: 1052 NSGTQQQGNGLF------QQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLS--- 1102
Query: 531 QQKPQDLSRSFINNPHPAMEPRQGNTK------PLFHFNSDQA---------NQQMPSVL 575
Q+ S ++P+P + + T P+FH S A +QQ ++
Sbjct: 1103 ----QETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIF 1158
Query: 576 PSQ--------------------NKPSLLHYTQQQQQQQQQQQQQ-----QQQQQQQQQQ 610
SQ N S L T +QQ QQQ Q Q+Q
Sbjct: 1159 LSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQA 1218
Query: 611 QQQQQQQQQQQSSISA-------QQQQ----QQQSSISAQQ-----QQQQQQQQQQQQQQ 654
Q QQ Q Q ++ + Q QQ Q Q SI A Q Q+QQQQQQQQQQQQ
Sbjct: 1219 QPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQ 1278
Query: 655 QQQQQQQQQQQPSSQPAQSLPSQPLLRSPL-PLQQKLLLQQMQNQPI-------AGMGYQ 706
QQQQQ ++ + P QP P Q + Q+ QNQ I A M +
Sbjct: 1279 QQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQE 1338
Query: 707 VSQQQRQDQHSVVG-QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIM 765
Q Q Q +V QN GP+ S +SQ L + + Q +Q
Sbjct: 1339 QQPMQFQSQSTVSSLQNPGPTQSE-------------SSQTPLFHSS--PQIQLVQGSPS 1383
Query: 766 EQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVG----NMQPTAQYSGGS 821
Q+QQ+ L L+ A A Q IN+ + P Y Q G P Q +
Sbjct: 1384 SQEQQVTL---FLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFH 1440
Query: 822 STISLNSNQALANPVSTHTI-------LTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLP 874
+T NQ +P S+ + N S L TS +P A+ G N
Sbjct: 1441 NTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNE- 1499
Query: 875 CNQPNTYSVTSGMNQLTQQRNP--KQLLANQNNPMMPRPPTLGPSNNNNVATF 925
QP VT+ ++Q + +P + NQN + +L NN +F
Sbjct: 1500 -GQP---PVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1548
Score = 73.9 bits (180), Expect = 8e-13
Identities = 224/1035 (21%), Positives = 359/1035 (34%), Gaps = 193/1035 (18%)
Query: 232 TLPMSQAPLRKTNTLPSH-------THSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMT 284
TLP+S TN SH T P G N+ +K+ P S + M T
Sbjct: 535 TLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAGALNVNVKKEISSPARPCSFEEAMKAMKT 594
Query: 285 ------QENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIK--- 335
+ NI PN LM P + + +++ ++ + + I T K
Sbjct: 595 TGCNLDKVNIIPNA--------LMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVG 646
Query: 336 --QDDPFNID--LGQQSQRSTPRPSLPME----KIVIKSEYSPGLTQGPSGSPQLRPPSA 387
Q NI G S S LP E + + Y+P T + + P
Sbjct: 647 STQQTLENISNIAGNGSFSSPSSSHLPSENEKQQQIQPKAYNPE-TLTTIQTQDISQPGT 705
Query: 388 GPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRA-LPSWQEVSHAQQLKQIAANRQQH 446
PA S A+S L S ++ Q Q QT SR L S V + QL + + +QQ
Sbjct: 706 FPAVS-ASSQLPNSD---ALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQS 761
Query: 447 ARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQ 506
+Q Q Q + + PS S +++ + SF T S S + V
Sbjct: 762 PLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEA 821
Query: 507 SKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQ 566
+ +++ ++ SA G+ +V +Q D+ + +T+P H D
Sbjct: 822 QQQLSSVLF----SAPDGNENV-QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPD- 875
Query: 567 ANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISA 626
++LP + + Q + QQQQQQQQQQ + + QQS A
Sbjct: 876 ------NLLPGRAES-----VHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQA 924
Query: 627 QQQQQQQ---SSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
Q Q + S+ SA QQ QQ + Q + S P+ +
Sbjct: 925 AAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETS 984
Query: 684 LPLQQKLLL--QQMQNQPIAGMGYQVSQQQRQDQHSVVG-----QNTGPS-PSPNPCSNP 735
Q++ M +G G + Q +Q Q+SV Q++G + P N S+
Sbjct: 985 TTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSST 1044
Query: 736 NTGSGYMNS----------QQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIA 785
+ NS QQ N+ + + +Q + QL Q +ADA+ ++
Sbjct: 1045 KSMMSVQNSGTQQQGNGLFQQG--NEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLS 1102
Query: 786 PQDQINR-HLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNS-------------NQA 831
+ Q + H P + + MQP +S + + S +Q+
Sbjct: 1103 QETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQS 1162
Query: 832 LANPVSTHTI------LTPN--SSLLSTSHGTRM--------------PSLS---TAVQN 866
N + T+T+ PN S L STS+ + P LS
Sbjct: 1163 PMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQ 1222
Query: 867 MGMY------GNLPCN--------------------QPNTYSVTSGMNQLTQQRNPKQ-- 898
G++ G+LP N Q N+ S Q QQ+ +Q
Sbjct: 1223 QGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQ 1282
Query: 899 ---LLANQN------NPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMPP 949
L +NQN +P P P + N N +A N +Q ++ H ++M P
Sbjct: 1283 QSILFSNQNTMATMASPKQPPPNMIFNPNQNPMA--------NQEQQNQSIFHQQSNMAP 1334
Query: 950 --QRTSNVMITSNTTAPNWASQEGTSKQQEAL----TSAGVRFPTGTPAAYTPN------ 997
Q + S +T + + T + +S ++ G+P++
Sbjct: 1335 MNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLS 1394
Query: 998 ----QSLQQAVGSQQFSQRAVAPPNQLTPAVQ-----MRPMNQMSQTLNGQTMGPLRGLN 1048
+LQ ++ Q Q + P P +Q +P + G TM L+
Sbjct: 1395 PASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNSP 1454
Query: 1049 LRPNQLSTQIL----PNLNQSGTG----LNQSRTGINQPPSLTPSNFPSPNQSSRAFQGT 1100
Q S L N +Q T L I+QP P N P ++ Q
Sbjct: 1455 GSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQ--PQNEGQPPVTTLLSQQM 1512
Query: 1101 DHSSDLAFDFLSQQN 1115
+S LA + QN
Sbjct: 1513 PENSPLASSINTNQN 1527
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 83.6 bits (205), Expect = 1e-15
Identities = 177/713 (24%), Positives = 257/713 (36%), Gaps = 152/713 (21%)
Query: 317 SVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIV------IKSEYSP 370
SV P S+ L N +Q QQ S+ + M++ + I+SE P
Sbjct: 885 SVHPQSENTLSNQQQQQQQQ---------QQVMESSAAMVMEMQQSICQAAAQIQSELFP 935
Query: 371 GLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEV 430
T +G+ Q P + M SALST+ + + + P SG + + Q+V
Sbjct: 936 S-TASANGNLQQSPVYQQTSHMM--SALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQV 992
Query: 431 SH-----------------AQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPG 473
+ Q KQI + Q QH +QP + + S
Sbjct: 993 ATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQ 1052
Query: 474 PFGQEKIPSPSFGQQTFSPQSSPMPGVAGGS---GQSKVMANYMYKAGPSAQGGHLDVLM 530
G ++ + F Q + M + G+ S A + P A +L
Sbjct: 1053 NSGTQQQGNGLF------QQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLS--- 1103
Query: 531 QQKPQDLSRSFINNPHPAMEPRQGNTK------PLFHFNSDQA---------NQQMPSVL 575
Q+ S ++P+P + + T P+FH S A +QQ ++
Sbjct: 1104 ----QETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIF 1159
Query: 576 PSQ--------------------NKPSLLHYTQQQQQQQQQQQQQ-----QQQQQQQQQQ 610
SQ N S L T +QQ QQQ Q Q+Q
Sbjct: 1160 LSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQA 1219
Query: 611 QQQQQQQQQQQSSISA-------QQQQ----QQQSSISAQQ-----QQQQQQQQQQQQQQ 654
Q QQ Q Q ++ + Q QQ Q Q SI A Q Q+QQQQQQQQQQQQ
Sbjct: 1220 QPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQ 1279
Query: 655 QQQQQQQQQQQPSSQPAQSLPSQPLLRSPL-PLQQKLLLQQMQNQPI-------AGMGYQ 706
QQQQQ ++ + P QP P Q + Q+ QNQ I A M +
Sbjct: 1280 QQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQE 1339
Query: 707 VSQQQRQDQHSVVG-QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIM 765
Q Q Q +V QN GP+ S +SQ L + + Q +Q
Sbjct: 1340 QQPMQFQSQSTVSSLQNPGPTQSE-------------SSQTPLFHSS--PQIQLVQGSPS 1384
Query: 766 EQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVG----NMQPTAQYSGGS 821
Q+QQ+ L L+ A A Q IN+ + P Y Q G P Q +
Sbjct: 1385 SQEQQVTL---FLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFH 1441
Query: 822 STISLNSNQALANPVSTHTI-------LTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLP 874
+T NQ +P S+ + N S L TS +P A+ G N
Sbjct: 1442 NTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNE- 1500
Query: 875 CNQPNTYSVTSGMNQLTQQRNP--KQLLANQNNPMMPRPPTLGPSNNNNVATF 925
QP VT+ ++Q + +P + NQN + +L NN +F
Sbjct: 1501 -GQP---PVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1549
Score = 71.2 bits (173), Expect = 5e-12
Identities = 224/1036 (21%), Positives = 361/1036 (34%), Gaps = 194/1036 (18%)
Query: 232 TLPMSQAPLRKTNTLPSH-----THSP---GNGLFNMGLKEVKKEPGETLSCSKHMDGQM 283
TLP+S TN SH T++P G N+ +K+ P S + M
Sbjct: 535 TLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMK 594
Query: 284 T------QENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIK-- 335
T + NI PN LM P + + +++ ++ + + I T K
Sbjct: 595 TTGCNLDKVNIIPNA--------LMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSV 646
Query: 336 ---QDDPFNID--LGQQSQRSTPRPSLPME----KIVIKSEYSPGLTQGPSGSPQLRPPS 386
Q NI G S S LP E + + Y+P T + + P
Sbjct: 647 GSTQQTLENISNIAGNGSFSSPSSSHLPSENEKQQQIQPKAYNPE-TLTTIQTQDISQPG 705
Query: 387 AGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRA-LPSWQEVSHAQQLKQIAANRQQ 445
PA S A+S L S ++ Q Q QT SR L S V + QL + + +QQ
Sbjct: 706 TFPAVS-ASSQLPNSD---ALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQ 761
Query: 446 HARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSG 505
+Q Q Q + + PS S +++ + SF T S S + V
Sbjct: 762 SPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLE 821
Query: 506 QSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSD 565
+ +++ ++ SA G+ +V +Q D+ + +T+P H D
Sbjct: 822 AQQQLSSVLF----SAPDGNENV-QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPD 876
Query: 566 QANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSIS 625
++LP + + Q + QQQQQQQQQQ + + QQS
Sbjct: 877 -------NLLPGRAES-----VHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQ 924
Query: 626 AQQQQQQQ---SSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS 682
A Q Q + S+ SA QQ QQ + Q + S P+ +
Sbjct: 925 AAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNET 984
Query: 683 PLPLQQKLLL--QQMQNQPIAGMGYQVSQQQRQDQHSVVG-----QNTGPS-PSPNPCSN 734
Q++ M +G G + Q +Q Q+SV Q++G + P N S+
Sbjct: 985 STTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSS 1044
Query: 735 PNTGSGYMNS----------QQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKI 784
+ NS QQ N+ + + +Q + QL Q +ADA+ +
Sbjct: 1045 TKSMMSVQNSGTQQQGNGLFQQG--NEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNL 1102
Query: 785 APQDQINR-HLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNS-------------NQ 830
+ + Q + H P + + MQP +S + + S +Q
Sbjct: 1103 SQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQ 1162
Query: 831 ALANPVSTHTI------LTPN--SSLLSTSHGTRM--------------PSLS---TAVQ 865
+ N + T+T+ PN S L STS+ + P LS
Sbjct: 1163 SPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPP 1222
Query: 866 NMGMY------GNLPCN--------------------QPNTYSVTSGMNQLTQQRNPKQ- 898
G++ G+LP N Q N+ S Q QQ+ +Q
Sbjct: 1223 QQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQ 1282
Query: 899 ----LLANQN------NPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMP 948
L +NQN +P P P + N N +A N +Q ++ H ++M
Sbjct: 1283 QQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMA--------NQEQQNQSIFHQQSNMA 1334
Query: 949 P--QRTSNVMITSNTTAPNWASQEGTSKQQEAL----TSAGVRFPTGTPAAYTPN----- 997
P Q + S +T + + T + +S ++ G+P++
Sbjct: 1335 PMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFL 1394
Query: 998 -----QSLQQAVGSQQFSQRAVAPPNQLTPAVQ-----MRPMNQMSQTLNGQTMGPLRGL 1047
+LQ ++ Q Q + P P +Q +P + G TM L+
Sbjct: 1395 SPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNS 1454
Query: 1048 NLRPNQLSTQIL----PNLNQSGTG----LNQSRTGINQPPSLTPSNFPSPNQSSRAFQG 1099
Q S L N +Q T L I+QP P N P ++ Q
Sbjct: 1455 PGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQ--PQNEGQPPVTTLLSQQ 1512
Query: 1100 TDHSSDLAFDFLSQQN 1115
+S LA + QN
Sbjct: 1513 MPENSPLASSINTNQN 1528
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 83.6 bits (205), Expect = 1e-15
Identities = 177/713 (24%), Positives = 257/713 (36%), Gaps = 152/713 (21%)
Query: 317 SVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIV------IKSEYSP 370
SV P S+ L N +Q QQ S+ + M++ + I+SE P
Sbjct: 791 SVHPQSENTLSNQQQQQQQQ---------QQVMESSAAMVMEMQQSICQAAAQIQSELFP 841
Query: 371 GLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEV 430
T +G+ Q P + M SALST+ + + + P SG + + Q+V
Sbjct: 842 S-TASANGNLQQSPVYQQTSHMM--SALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQV 898
Query: 431 SH-----------------AQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPG 473
+ Q KQI + Q QH +QP + + S
Sbjct: 899 ATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQ 958
Query: 474 PFGQEKIPSPSFGQQTFSPQSSPMPGVAGGS---GQSKVMANYMYKAGPSAQGGHLDVLM 530
G ++ + F Q + M + G+ S A + P A +L
Sbjct: 959 NSGTQQQGNGLF------QQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLS--- 1009
Query: 531 QQKPQDLSRSFINNPHPAMEPRQGNTK------PLFHFNSDQA---------NQQMPSVL 575
Q+ S ++P+P + + T P+FH S A +QQ ++
Sbjct: 1010 ----QETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIF 1065
Query: 576 PSQ--------------------NKPSLLHYTQQQQQQQQQQQQQ-----QQQQQQQQQQ 610
SQ N S L T +QQ QQQ Q Q+Q
Sbjct: 1066 LSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQA 1125
Query: 611 QQQQQQQQQQQSSISA-------QQQQ----QQQSSISAQQ-----QQQQQQQQQQQQQQ 654
Q QQ Q Q ++ + Q QQ Q Q SI A Q Q+QQQQQQQQQQQQ
Sbjct: 1126 QPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQ 1185
Query: 655 QQQQQQQQQQQPSSQPAQSLPSQPLLRSPL-PLQQKLLLQQMQNQPI-------AGMGYQ 706
QQQQQ ++ + P QP P Q + Q+ QNQ I A M +
Sbjct: 1186 QQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQE 1245
Query: 707 VSQQQRQDQHSVVG-QNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIM 765
Q Q Q +V QN GP+ S +SQ L + + Q +Q
Sbjct: 1246 QQPMQFQSQSTVSSLQNPGPTQSE-------------SSQTPLFHSS--PQIQLVQGSPS 1290
Query: 766 EQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVG----NMQPTAQYSGGS 821
Q+QQ+ L L+ A A Q IN+ + P Y Q G P Q +
Sbjct: 1291 SQEQQVTL---FLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFH 1347
Query: 822 STISLNSNQALANPVSTHTI-------LTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLP 874
+T NQ +P S+ + N S L TS +P A+ G N
Sbjct: 1348 NTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNE- 1406
Query: 875 CNQPNTYSVTSGMNQLTQQRNP--KQLLANQNNPMMPRPPTLGPSNNNNVATF 925
QP VT+ ++Q + +P + NQN + +L NN +F
Sbjct: 1407 -GQP---PVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF 1455
Score = 71.2 bits (173), Expect = 5e-12
Identities = 224/1036 (21%), Positives = 361/1036 (34%), Gaps = 194/1036 (18%)
Query: 232 TLPMSQAPLRKTNTLPSH-----THSP---GNGLFNMGLKEVKKEPGETLSCSKHMDGQM 283
TLP+S TN SH T++P G N+ +K+ P S + M
Sbjct: 441 TLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMK 500
Query: 284 T------QENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIK-- 335
T + NI PN LM P + + +++ ++ + + I T K
Sbjct: 501 TTGCNLDKVNIIPNA--------LMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSV 552
Query: 336 ---QDDPFNID--LGQQSQRSTPRPSLPME----KIVIKSEYSPGLTQGPSGSPQLRPPS 386
Q NI G S S LP E + + Y+P T + + P
Sbjct: 553 GSTQQTLENISNIAGNGSFSSPSSSHLPSENEKQQQIQPKAYNPE-TLTTIQTQDISQPG 611
Query: 387 AGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRA-LPSWQEVSHAQQLKQIAANRQQ 445
PA S A+S L S ++ Q Q QT SR L S V + QL + + +QQ
Sbjct: 612 TFPAVS-ASSQLPNSD---ALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQ 667
Query: 446 HARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSG 505
+Q Q Q + + PS S +++ + SF T S S + V
Sbjct: 668 SPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLE 727
Query: 506 QSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSD 565
+ +++ ++ SA G+ +V +Q D+ + +T+P H D
Sbjct: 728 AQQQLSSVLF----SAPDGNENV-QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPD 782
Query: 566 QANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSIS 625
++LP + + Q + QQQQQQQQQQ + + QQS
Sbjct: 783 -------NLLPGRAES-----VHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQ 830
Query: 626 AQQQQQQQ---SSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS 682
A Q Q + S+ SA QQ QQ + Q + S P+ +
Sbjct: 831 AAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNET 890
Query: 683 PLPLQQKLLL--QQMQNQPIAGMGYQVSQQQRQDQHSVVG-----QNTGPS-PSPNPCSN 734
Q++ M +G G + Q +Q Q+SV Q++G + P N S+
Sbjct: 891 STTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSS 950
Query: 735 PNTGSGYMNS----------QQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKI 784
+ NS QQ N+ + + +Q + QL Q +ADA+ +
Sbjct: 951 TKSMMSVQNSGTQQQGNGLFQQG--NEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNL 1008
Query: 785 APQDQINR-HLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNS-------------NQ 830
+ + Q + H P + + MQP +S + + S +Q
Sbjct: 1009 SQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQ 1068
Query: 831 ALANPVSTHTI------LTPN--SSLLSTSHGTRM--------------PSLS---TAVQ 865
+ N + T+T+ PN S L STS+ + P LS
Sbjct: 1069 SPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPP 1128
Query: 866 NMGMY------GNLPCN--------------------QPNTYSVTSGMNQLTQQRNPKQ- 898
G++ G+LP N Q N+ S Q QQ+ +Q
Sbjct: 1129 QQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQ 1188
Query: 899 ----LLANQN------NPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLTHSMASMP 948
L +NQN +P P P + N N +A N +Q ++ H ++M
Sbjct: 1189 QQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMA--------NQEQQNQSIFHQQSNMA 1240
Query: 949 P--QRTSNVMITSNTTAPNWASQEGTSKQQEAL----TSAGVRFPTGTPAAYTPN----- 997
P Q + S +T + + T + +S ++ G+P++
Sbjct: 1241 PMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFL 1300
Query: 998 -----QSLQQAVGSQQFSQRAVAPPNQLTPAVQ-----MRPMNQMSQTLNGQTMGPLRGL 1047
+LQ ++ Q Q + P P +Q +P + G TM L+
Sbjct: 1301 SPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNS 1360
Query: 1048 NLRPNQLSTQIL----PNLNQSGTG----LNQSRTGINQPPSLTPSNFPSPNQSSRAFQG 1099
Q S L N +Q T L I+QP P N P ++ Q
Sbjct: 1361 PGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQ--PQNEGQPPVTTLLSQQ 1418
Query: 1100 TDHSSDLAFDFLSQQN 1115
+S LA + QN
Sbjct: 1419 MPENSPLASSINTNQN 1434
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.123 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,029,701
Number of Sequences: 37866
Number of extensions: 3032170
Number of successful extensions: 103911
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1010
Number of HSP's successfully gapped in prelim test: 799
Number of HSP's that attempted gapping in prelim test: 29947
Number of HSP's gapped (non-prelim): 24400
length of query: 1156
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1043
effective length of database: 13,968,660
effective search space: 14569312380
effective search space used: 14569312380
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.