Guide to the Human Genome
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Search of human proteins with 33286434

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33286434 p47 protein isoform c [Homo sapiens]
         (259 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33286434 p47 protein isoform c [Homo sapiens]                      508   e-144
gi|20149635 p47 protein isoform a [Homo sapiens]                      484   e-137
gi|29568099 p47 protein isoform b [Homo sapiens]                      405   e-113
gi|117938297 UBX domain protein 2B [Homo sapiens]                     287   7e-78
gi|33457320 UBX domain containing 4 [Homo sapiens]                    147   7e-36
gi|116734689 socius isoform 3 [Homo sapiens]                           42   7e-04
gi|116734681 socius isoform 1 [Homo sapiens]                           42   7e-04
gi|116734679 socius isoform 2 [Homo sapiens]                           42   7e-04
gi|13129078 alveolar soft part sarcoma chromosome region, candid...    41   0.001
gi|29725609 epidermal growth factor receptor isoform a precursor...    32   0.42 
gi|122937512 myosin VIIB [Homo sapiens]                                31   1.2  
gi|17978479 vacuolar protein sorting 16 isoform 1 [Homo sapiens]       30   2.1  
gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]     30   2.1  
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [...    30   2.1  
gi|17978481 vacuolar protein sorting 16 isoform 3 [Homo sapiens]       30   2.7  
gi|139394579 zinc finger and BTB domain containing 40 [Homo sapi...    30   2.7  
gi|139394556 zinc finger and BTB domain containing 40 [Homo sapi...    30   2.7  
gi|21361517 UBX domain protein 1 [Homo sapiens]                        30   2.7  
gi|94536798 high mobility group AT-hook 1-like 4 [Homo sapiens]        29   3.6  
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    29   4.7  
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    29   4.7  
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    29   4.7  
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    29   4.7  
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    29   4.7  
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    29   4.7  
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho...    28   6.1  
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora...    28   8.0  
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora...    28   8.0  
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora...    28   8.0  
gi|32454739 tripartite motif-containing 3 [Homo sapiens]               28   8.0  

>gi|33286434 p47 protein isoform c [Homo sapiens]
          Length = 259

 Score =  508 bits (1307), Expect = e-144
 Identities = 259/259 (100%), Positives = 259/259 (100%)

Query: 1   MTKMKMRRKRKARGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGE 60
           MTKMKMRRKRKARGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGE
Sbjct: 1   MTKMKMRRKRKARGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGE 60

Query: 61  KRQHSSQDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQV 120
           KRQHSSQDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQV
Sbjct: 61  KRQHSSQDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQV 120

Query: 121 NLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDE 180
           NLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDE
Sbjct: 121 NLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDE 180

Query: 181 SEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADE 240
           SEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADE
Sbjct: 181 SEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADE 240

Query: 241 SQTLKEANLLNAVIVQRLT 259
           SQTLKEANLLNAVIVQRLT
Sbjct: 241 SQTLKEANLLNAVIVQRLT 259


>gi|20149635 p47 protein isoform a [Homo sapiens]
          Length = 370

 Score =  484 bits (1245), Expect = e-137
 Identities = 246/247 (99%), Positives = 247/247 (100%)

Query: 13  RGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVV 72
           +GAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVV
Sbjct: 124 KGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVV 183

Query: 73  LKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDF 132
           LKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDF
Sbjct: 184 LKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDF 243

Query: 133 VKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLA 192
           VKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLA
Sbjct: 244 VKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLA 303

Query: 193 DGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNA 252
           DGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNA
Sbjct: 304 DGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNA 363

Query: 253 VIVQRLT 259
           VIVQRLT
Sbjct: 364 VIVQRLT 370


>gi|29568099 p47 protein isoform b [Homo sapiens]
          Length = 339

 Score =  405 bits (1040), Expect = e-113
 Identities = 215/247 (87%), Positives = 216/247 (87%), Gaps = 31/247 (12%)

Query: 13  RGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVV 72
           +GAKEHGAVAVERVTKSPGETSKPR                               VHVV
Sbjct: 124 KGAKEHGAVAVERVTKSPGETSKPR-------------------------------VHVV 152

Query: 73  LKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDF 132
           LKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDF
Sbjct: 153 LKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDF 212

Query: 133 VKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLA 192
           VKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLA
Sbjct: 213 VKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLA 272

Query: 193 DGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNA 252
           DGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNA
Sbjct: 273 DGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNA 332

Query: 253 VIVQRLT 259
           VIVQRLT
Sbjct: 333 VIVQRLT 339


>gi|117938297 UBX domain protein 2B [Homo sapiens]
          Length = 331

 Score =  287 bits (734), Expect = 7e-78
 Identities = 140/244 (57%), Positives = 192/244 (78%), Gaps = 5/244 (2%)

Query: 15  AKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVVLK 74
           A+EHGAV +   T++ G+  K + F GGGYRLG++  + S Y+ GE +    QDV ++LK
Sbjct: 92  AREHGAVPLNEATRASGD-DKSKSFTGGGYRLGSSFCKRSEYIYGENQL---QDVQILLK 147

Query: 75  LWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVK 134
           LW +GFSLD+GELR Y +P+NAQFLES++RGE+P EL+RL HGGQVNLDMEDH+D++++K
Sbjct: 148 LWSNGFSLDDGELRPYNEPTNAQFLESVKRGEIPLELQRLVHGGQVNLDMEDHQDQEYIK 207

Query: 135 PKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLADG 194
           P+  FKAF+GEGQKLGS  P+++ST S  ++ E+++  ++ +LID+S PTT IQIRLADG
Sbjct: 208 PRLRFKAFSGEGQKLGSLTPEIVSTPSSPEE-EDKSILNAVVLIDDSVPTTKIQIRLADG 266

Query: 195 GRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNAVI 254
            RL+Q+FN +HRI D+R FIV +RP  AA  FIL+T+FPNKEL DES TL EA++LN V+
Sbjct: 267 SRLIQRFNSTHRILDVRNFIVQSRPEFAALDFILVTSFPNKELTDESLTLLEADILNTVL 326

Query: 255 VQRL 258
           +Q+L
Sbjct: 327 LQQL 330


>gi|33457320 UBX domain containing 4 [Homo sapiens]
          Length = 259

 Score =  147 bits (372), Expect = 7e-36
 Identities = 83/193 (43%), Positives = 129/193 (66%), Gaps = 5/193 (2%)

Query: 67  QDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMED 126
           + V V +KLWK+GF++ N + RSY D ++ QFL SI++GE+P+EL+ +    +V++ +ED
Sbjct: 59  KQVDVNIKLWKNGFTV-NDDFRSYSDGASQQFLNSIKKGELPSELQGIFDKEEVDVKVED 117

Query: 127 HRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKAS-SSILIDESEPTT 185
            ++E  +  K  F+ F+G+G +LGS  P+++S    A+  E E K + S++ ++  EP T
Sbjct: 118 KKNEICLSTKPVFQPFSGQGHRLGSATPKIVSK---AKNIEVENKNNLSAVPLNNLEPIT 174

Query: 186 NIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLK 245
           NIQI LA+G R+VQKFN +HR+S I+ FI   + +  +  F L T  P   L DE+ TL+
Sbjct: 175 NIQIWLANGKRIVQKFNITHRVSHIKDFIEKYQGSQRSPPFSLATALPVLRLLDETLTLE 234

Query: 246 EANLLNAVIVQRL 258
           EA+L NAVI+QRL
Sbjct: 235 EADLQNAVIIQRL 247


>gi|116734689 socius isoform 3 [Homo sapiens]
          Length = 400

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 25/80 (31%), Positives = 44/80 (55%), Gaps = 3/80 (3%)

Query: 71  VVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDE 130
           + LKL+++G  + +G  + + DPS  + L  I  G  P+EL+RL   G V   + D R++
Sbjct: 113 IPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNG-VPFKVSDLRNQ 171

Query: 131 DFVKPKGAFKAFTGEGQKLG 150
            ++  +     F GEG+ +G
Sbjct: 172 VYL--EDGLDPFPGEGRVVG 189


>gi|116734681 socius isoform 1 [Homo sapiens]
          Length = 487

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 25/80 (31%), Positives = 44/80 (55%), Gaps = 3/80 (3%)

Query: 71  VVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDE 130
           + LKL+++G  + +G  + + DPS  + L  I  G  P+EL+RL   G V   + D R++
Sbjct: 200 IPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNG-VPFKVSDLRNQ 258

Query: 131 DFVKPKGAFKAFTGEGQKLG 150
            ++  +     F GEG+ +G
Sbjct: 259 VYL--EDGLDPFPGEGRVVG 276


>gi|116734679 socius isoform 2 [Homo sapiens]
          Length = 520

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 25/80 (31%), Positives = 44/80 (55%), Gaps = 3/80 (3%)

Query: 71  VVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDE 130
           + LKL+++G  + +G  + + DPS  + L  I  G  P+EL+RL   G V   + D R++
Sbjct: 233 IPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNG-VPFKVSDLRNQ 291

Query: 131 DFVKPKGAFKAFTGEGQKLG 150
            ++  +     F GEG+ +G
Sbjct: 292 VYL--EDGLDPFPGEGRVVG 309


>gi|13129078 alveolar soft part sarcoma chromosome region, candidate
           1 [Homo sapiens]
          Length = 553

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 59/228 (25%), Positives = 83/228 (36%), Gaps = 21/228 (9%)

Query: 38  PFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNGELRSYQDPSNAQ 97
           PF+GGG RLG  P        G  R  +S    +   L   G      + +S QDP   Q
Sbjct: 244 PFSGGGQRLGGPP--------GPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQ 295

Query: 98  FLESIRRGEVPAELRRLAHGGQVNL-------DMEDHRDEDFVKPKGAFKAFTGEGQKLG 150
             E  R  +   E  R      V+        D+E+       +    F   T +  +  
Sbjct: 296 EQERERDPQQEQERERPVDREPVDREPVVCHPDLEERLQAWPAELPDEFFELTVDDVR-- 353

Query: 151 STAPQVLSTSSPAQQAENEAKASSSILIDES---EPTTNIQIRLADGGRLVQKFNHSHRI 207
               Q+ S     ++A    KA     I E     P   +++   D   L   F  S  +
Sbjct: 354 RRLAQLKSERKRLEEAPLVTKAFREAQIKEKLERYPKVALRVLFPDRYVLQGFFRPSETV 413

Query: 208 SDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNAVIV 255
            D+R F V +       SF L  T P   L D +QTL +ANL  A +V
Sbjct: 414 GDLRDF-VRSHLGNPELSFYLFITPPKTVLDDHTQTLFQANLFPAALV 460


>gi|29725609 epidermal growth factor receptor isoform a precursor
            [Homo sapiens]
          Length = 1210

 Score = 32.3 bits (72), Expect = 0.42
 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 13/79 (16%)

Query: 90   YQDP-----SNAQFLESIRRGEVPAELRRLAHGGQ-----VNLDMEDHRDEDF---VKPK 136
            YQDP      N ++L +++   V +     AH  Q     ++LD  D++ + F    KP 
Sbjct: 1125 YQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPN 1184

Query: 137  GAFKAFTGEGQKLGSTAPQ 155
            G FK  T E  +    APQ
Sbjct: 1185 GIFKGSTAENAEYLRVAPQ 1203


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 28/117 (23%), Positives = 48/117 (41%), Gaps = 13/117 (11%)

Query: 51   EEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAE 110
            +E   Y+ G  +      +H+   ++K+ F+ D  +L S         +  I R  VP  
Sbjct: 1914 QELPKYLRGFHKCSREDAIHLAGLIYKAQFNNDRSQLAS---------VPKILRELVPEN 1964

Query: 111  LRRLAHGGQ----VNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPA 163
            L RL    +    + L  + H+D+   + K AF  +       GS   +V  TS P+
Sbjct: 1965 LTRLMSSEEWKKSILLAYDKHKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPS 2021


>gi|17978479 vacuolar protein sorting 16 isoform 1 [Homo sapiens]
          Length = 839

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 46/185 (24%), Positives = 73/185 (39%), Gaps = 27/185 (14%)

Query: 22  AVERVTKSPGETSKP-------RPFAGGGYRLGAAPEEESAYVAGEKRQ-HSSQDVHVVL 73
           AV++  ++ G   +P       R  + G   L   P +   ++  + R  ++ +D H+ +
Sbjct: 379 AVQQCIEAAGHEHQPDMQKSLLRAASFGKCFLDRFPPDSFVHMCQDLRVLNAVRDYHIGI 438

Query: 74  KLWKSGFS-------LDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMED 126
            L  S +        LD   LR    P   Q  E +R  EV    R LAH     +  +D
Sbjct: 439 PLTYSQYKQLTIQVLLDRLVLRRLY-PLAIQICEYLRLPEVQGVSRILAHWACYKVQQKD 497

Query: 127 HRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTN 186
             DED  +            QKLG T    +S S  A +A    +   +I + E EP + 
Sbjct: 498 VSDEDVAR---------AINQKLGDTPG--VSYSDIAARAYGCGRTELAIKLLEYEPRSG 546

Query: 187 IQIRL 191
            Q+ L
Sbjct: 547 EQVPL 551


>gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens]
          Length = 2555

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 11/83 (13%)

Query: 28   KSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNGEL 87
            K+ GET    P   G   LG   +E  A+   EK+ H   +        K G +L    +
Sbjct: 1417 KNTGETGVEEPILEG--HLGVT-KELLAFQTSEKKYHFGCE--------KGGANLIKELI 1465

Query: 88   RSYQDPSNAQFLESIRRGEVPAE 110
              +  P++  +L+ +R GE+PAE
Sbjct: 1466 DDFIFPASKVYLQYLRSGELPAE 1488


>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
           [Homo sapiens]
          Length = 890

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 24/130 (18%)

Query: 124 MEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEP 183
           +ED ++ED++     F  F+G+     ST  + L  ++P    EN  +A + +   E + 
Sbjct: 311 LEDMQEEDYLN----FILFSGDV----STWKEHLVQATP----ENLQEARTFVKSMEDKG 358

Query: 184 TTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQT 243
            TNI   L  G  ++ K    HRI +             +TS ++M T  +  + +    
Sbjct: 359 MTNINDGLLRGISMLNKAREEHRIPE------------RSTSIVIMLTDGDANVGESRPE 406

Query: 244 LKEANLLNAV 253
             + N+ NA+
Sbjct: 407 KIQENVRNAI 416


>gi|17978481 vacuolar protein sorting 16 isoform 3 [Homo sapiens]
          Length = 695

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 11/99 (11%)

Query: 93  PSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGST 152
           P   Q  E +R  EV    R LAH     +  +D  DED  +            QKLG T
Sbjct: 320 PLAIQICEYLRLPEVQGVSRILAHWACYKVQQKDVSDEDVAR---------AINQKLGDT 370

Query: 153 APQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRL 191
               +S S  A +A    +   +I + E EP +  Q+ L
Sbjct: 371 PG--VSYSDIAARAYGCGRTELAIKLLEYEPRSGEQVPL 407


>gi|139394579 zinc finger and BTB domain containing 40 [Homo
           sapiens]
          Length = 1239

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 16/55 (29%), Positives = 26/55 (47%)

Query: 133 VKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNI 187
           ++ K  +K FT E + L  T  ++LS  S     E   +A  S  +++S P   I
Sbjct: 589 IQQKIEYKLFTSEEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEI 643


>gi|139394556 zinc finger and BTB domain containing 40 [Homo
           sapiens]
          Length = 1239

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 16/55 (29%), Positives = 26/55 (47%)

Query: 133 VKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNI 187
           ++ K  +K FT E + L  T  ++LS  S     E   +A  S  +++S P   I
Sbjct: 589 IQQKIEYKLFTSEEEHLAETVKEILSIPSETASPEASLRAVLSRAMEKSVPAIEI 643


>gi|21361517 UBX domain protein 1 [Homo sapiens]
          Length = 312

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 146 GQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLADGGRLVQKFNHSH 205
           G  +GS  P V     P   + ++   +             IQ+RL DG  L Q F    
Sbjct: 180 GGSVGSQPPPVAPEPGPVPSSPSQEPPTK-----REYDQCRIQVRLPDGTSLTQTFRARE 234

Query: 206 RISDIRLFI 214
           +++ +RL++
Sbjct: 235 QLAAVRLYV 243


>gi|94536798 high mobility group AT-hook 1-like 4 [Homo sapiens]
          Length = 356

 Score = 29.3 bits (64), Expect = 3.6
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 3/60 (5%)

Query: 3   KMKMRRKRKARGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLG---AAPEEESAYVAG 59
           + + RR + AR A+EH    +ER+TK+   + +       G R G   AAP     Y +G
Sbjct: 219 RARKRRLQAARRAEEHKNQTIERLTKTAATSGRGGRGGARGERRGGRAAAPAPMVRYCSG 278


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 19/153 (12%)

Query: 29  SPGETSKPRPFAGGGY---RLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNG 85
           +PG+ + P P    G    +  A   EE +  + E+   S ++      L ++  S    
Sbjct: 233 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 292

Query: 86  ELRSYQDPSNAQFLESIRRGEVPAELRRL------AHGGQVNLDMEDHRDEDFVKPKGAF 139
           ++ +   P+     ES R+G  PA   +       A  G+   D +   +E   + +   
Sbjct: 293 QVGAASAPAK----ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 348

Query: 140 KAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKA 172
           +A      K    APQV + S+PA+++  +  A
Sbjct: 349 QA------KPSGKAPQVRAASAPAKESPRKGAA 375


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 19/153 (12%)

Query: 29  SPGETSKPRPFAGGGY---RLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNG 85
           +PG+ + P P    G    +  A   EE +  + E+   S ++      L ++  S    
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369

Query: 86  ELRSYQDPSNAQFLESIRRGEVPAELRRL------AHGGQVNLDMEDHRDEDFVKPKGAF 139
           ++ +   P+     ES R+G  PA   +       A  G+   D +   +E   + +   
Sbjct: 370 QVGAASAPAK----ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425

Query: 140 KAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKA 172
           +A      K    APQV + S+PA+++  +  A
Sbjct: 426 QA------KPSGKAPQVRAASAPAKESPRKGAA 452


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 19/153 (12%)

Query: 29  SPGETSKPRPFAGGGY---RLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNG 85
           +PG+ + P P    G    +  A   EE +  + E+   S ++      L ++  S    
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369

Query: 86  ELRSYQDPSNAQFLESIRRGEVPAELRRL------AHGGQVNLDMEDHRDEDFVKPKGAF 139
           ++ +   P+     ES R+G  PA   +       A  G+   D +   +E   + +   
Sbjct: 370 QVGAASAPAK----ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425

Query: 140 KAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKA 172
           +A      K    APQV + S+PA+++  +  A
Sbjct: 426 QA------KPSGKAPQVRAASAPAKESPRKGAA 452


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 19/153 (12%)

Query: 29  SPGETSKPRPFAGGGY---RLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNG 85
           +PG+ + P P    G    +  A   EE +  + E+   S ++      L ++  S    
Sbjct: 233 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 292

Query: 86  ELRSYQDPSNAQFLESIRRGEVPAELRRL------AHGGQVNLDMEDHRDEDFVKPKGAF 139
           ++ +   P+     ES R+G  PA   +       A  G+   D +   +E   + +   
Sbjct: 293 QVGAASAPAK----ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 348

Query: 140 KAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKA 172
           +A      K    APQV + S+PA+++  +  A
Sbjct: 349 QA------KPSGKAPQVRAASAPAKESPRKGAA 375


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 19/153 (12%)

Query: 29  SPGETSKPRPFAGGGY---RLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNG 85
           +PG+ + P P    G    +  A   EE +  + E+   S ++      L ++  S    
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369

Query: 86  ELRSYQDPSNAQFLESIRRGEVPAELRRL------AHGGQVNLDMEDHRDEDFVKPKGAF 139
           ++ +   P+     ES R+G  PA   +       A  G+   D +   +E   + +   
Sbjct: 370 QVGAASAPAK----ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425

Query: 140 KAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKA 172
           +A      K    APQV + S+PA+++  +  A
Sbjct: 426 QA------KPSGKAPQVRAASAPAKESPRKGAA 452


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 19/153 (12%)

Query: 29  SPGETSKPRPFAGGGY---RLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNG 85
           +PG+ + P P    G    +  A   EE +  + E+   S ++      L ++  S    
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369

Query: 86  ELRSYQDPSNAQFLESIRRGEVPAELRRL------AHGGQVNLDMEDHRDEDFVKPKGAF 139
           ++ +   P+     ES R+G  PA   +       A  G+   D +   +E   + +   
Sbjct: 370 QVGAASAPAK----ESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPA 425

Query: 140 KAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKA 172
           +A      K    APQV + S+PA+++  +  A
Sbjct: 426 QA------KPSGKAPQVRAASAPAKESPRKGAA 452


>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
           sapiens]
          Length = 1484

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 15/115 (13%)

Query: 7   RRKRKARGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSS 66
           R KR++R  +  G+    R     G + K +P   GG  L   P   +     ++   S+
Sbjct: 558 REKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSL--PPTRRAPSSGDDQSSSST 615

Query: 67  QDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIR----------RGEVPAEL 111
           Q    V      GFS     L     PS A FL  +R          RG  PA L
Sbjct: 616 QPPREVGTSNGRGFS---HPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATL 667


>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 1 [Homo
            sapiens]
          Length = 1834

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 14/76 (18%)

Query: 18   HGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEE--------------ESAYVAGEKRQ 63
            H ++A++RVT+S  E  + + +    +R+ AA +               +S+  + E   
Sbjct: 1263 HSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLN 1322

Query: 64   HSSQDVHVVLKLWKSG 79
            HSS+ V     L KSG
Sbjct: 1323 HSSKSVTPASTLTKSG 1338


>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 2 [Homo
            sapiens]
          Length = 1651

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 14/76 (18%)

Query: 18   HGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEE--------------ESAYVAGEKRQ 63
            H ++A++RVT+S  E  + + +    +R+ AA +               +S+  + E   
Sbjct: 1264 HSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLN 1323

Query: 64   HSSQDVHVVLKLWKSG 79
            HSS+ V     L KSG
Sbjct: 1324 HSSKSVTPASTLTKSG 1339


>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 3 [Homo
            sapiens]
          Length = 1612

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 14/76 (18%)

Query: 18   HGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEE--------------ESAYVAGEKRQ 63
            H ++A++RVT+S  E  + + +    +R+ AA +               +S+  + E   
Sbjct: 1248 HSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLN 1307

Query: 64   HSSQDVHVVLKLWKSG 79
            HSS+ V     L KSG
Sbjct: 1308 HSSKSVTPASTLTKSG 1323


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 37/156 (23%), Positives = 57/156 (36%), Gaps = 37/156 (23%)

Query: 23  VERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSL 82
           V+R  KSPG         G   R  A     S Y  G KR+ +  +  +V ++   G   
Sbjct: 431 VKRRVKSPGGP-------GSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRG--R 481

Query: 83  DNGELRSYQD------------PSNAQFLESIR-----------RGEVPAELRR-----L 114
           + GE  + Q              SN Q ++              RG  P +L+R     +
Sbjct: 482 EKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAV 541

Query: 115 AHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLG 150
              G + +   D+R      P+G FK   G G+ +G
Sbjct: 542 DTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMG 577


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,658,861
Number of Sequences: 37866
Number of extensions: 442733
Number of successful extensions: 1174
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1146
Number of HSP's gapped (non-prelim): 43
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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