Search of human proteins with 32996735

Search of human proteins with 32996735

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32996735 Ras association (RalGDS/AF-6) domain family 5
isoform C [Homo sapiens]
         (265 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isofor...   527   e-150
gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isofor...   448   e-126
gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isofor...   277   8e-75
gi|25777682 Ras association domain family 1 isoform C [Homo sapi...   243   1e-64
gi|25777684 Ras association domain family 1 isoform D [Homo sapi...   228   5e-60
gi|20149588 Ras association domain family 1 isoform A [Homo sapi...   228   5e-60
gi|30039698 Ras association (RalGDS/AF-6) domain family member 3...   213   2e-55
gi|25777680 Ras association domain family 1 isoform B [Homo sapi...   211   7e-55
gi|25777677 Ras association domain family 2 [Homo sapiens]             73   2e-13
gi|7661964 Ras association domain family 2 [Homo sapiens]              73   2e-13
gi|23510360 Ras association domain family 4 [Homo sapiens]             61   1e-09
gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isofor...    56   3e-08
gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isofor...    56   3e-08
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora...    45   5e-05
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora...    45   5e-05
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora...    45   5e-05
gi|55770834 centromere protein F [Homo sapiens]                        36   0.030
gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 K...    34   0.15 
gi|178056552 non-SMC condensin I complex, subunit D2 [Homo sapiens]    33   0.26 
gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens]      33   0.26 
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        31   0.98 
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    31   1.3  
gi|217416354 sphingosine kinase type 1-interacting protein isofo...    30   1.7  
gi|217416352 sphingosine kinase type 1-interacting protein isofo...    30   1.7  
gi|169167074 PREDICTED: similar to SET translocation [Homo sapiens]    30   2.2  
gi|169166810 PREDICTED: similar to SET translocation [Homo sapiens]    30   2.2  
gi|169166302 PREDICTED: similar to SET translocation [Homo sapiens]    30   2.2  
gi|66392146 RNA U, small nuclear RNA export adaptor (phosphoryla...    30   2.2  
gi|21396489 mitochondrial lon peptidase 1 [Homo sapiens]               30   2.8  
gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]    30   2.8  

>gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isoform C
           [Homo sapiens]
          Length = 265

 Score =  527 bits (1357), Expect = e-150
 Identities = 265/265 (100%), Positives = 265/265 (100%)

Query: 1   MTVDSSMSSGYCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQ 60
           MTVDSSMSSGYCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQ
Sbjct: 1   MTVDSSMSSGYCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQ 60

Query: 61  KIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAAT 120
           KIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAAT
Sbjct: 61  KIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAAT 120

Query: 121 TDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQ 180
           TDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQ
Sbjct: 121 TDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQ 180

Query: 181 KLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQ 240
           KLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQ
Sbjct: 181 KLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQ 240

Query: 241 QVQKKYDKFRQKLEEALRESQGKPG 265
           QVQKKYDKFRQKLEEALRESQGKPG
Sbjct: 241 QVQKKYDKFRQKLEEALRESQGKPG 265


>gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isoform A
           [Homo sapiens]
          Length = 418

 Score =  448 bits (1153), Expect = e-126
 Identities = 226/227 (99%), Positives = 227/227 (100%)

Query: 39  SKNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVT 98
           S+NVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVT
Sbjct: 192 SQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVT 251

Query: 99  VPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMV 158
           VPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMV
Sbjct: 252 VPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMV 311

Query: 159 VDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDA 218
           VDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDA
Sbjct: 312 VDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDA 371

Query: 219 FSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG 265
           FSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG
Sbjct: 372 FSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG 418


>gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isoform B
           [Homo sapiens]
          Length = 336

 Score =  277 bits (708), Expect = 8e-75
 Identities = 138/139 (99%), Positives = 139/139 (100%)

Query: 39  SKNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVT 98
           S+NVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVT
Sbjct: 192 SQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVT 251

Query: 99  VPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMV 158
           VPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMV
Sbjct: 252 VPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMV 311

Query: 159 VDNPQKFALFKRIHKDGQV 177
           VDNPQKFALFKRIHKDGQV
Sbjct: 312 VDNPQKFALFKRIHKDGQV 330


>gi|25777682 Ras association domain family 1 isoform C [Homo
           sapiens]
          Length = 270

 Score =  243 bits (621), Expect = 1e-64
 Identities = 132/260 (50%), Positives = 180/260 (69%), Gaps = 9/260 (3%)

Query: 1   MTVDSSMSSGYCSL---DEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQE 57
           MT  S+ SSGYCS    D ELE  +FTA+T+  R  +     ++  +PVE      +  E
Sbjct: 11  MTWSSTTSSGYCSQEDSDSELEQ-YFTARTSLARRPR-----RDQDEPVEWETPDLSQAE 64

Query: 58  IKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNL 117
           I+QKI  YN +  + L M L++DG+YTGFIKV LKL RPV+VP+  +P S+ DA +    
Sbjct: 65  IEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGR 124

Query: 118 AATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQV 177
             +  +RTSFYLP DA+K LH+ S T   EVI+ LL+KF+VVD+P+KFALF+R  + GQV
Sbjct: 125 GTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQV 184

Query: 178 LFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQD 237
             +KL   ++PL LRLLAGP  + LSFVLKEN++GEV WDAFS+PEL NFL IL++EE++
Sbjct: 185 YLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEE 244

Query: 238 KIQQVQKKYDKFRQKLEEAL 257
            ++Q+ +KY   RQK++EAL
Sbjct: 245 HLRQILQKYSYCRQKIQEAL 264


>gi|25777684 Ras association domain family 1 isoform D [Homo
           sapiens]
          Length = 344

 Score =  228 bits (580), Expect = 5e-60
 Identities = 116/217 (53%), Positives = 157/217 (72%)

Query: 41  NVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVP 100
           NV +PVE      +  EI+QKI  YN +  + L M L++DG+YTGFIKV LKL RPV+VP
Sbjct: 122 NVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVP 181

Query: 101 AGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVD 160
           +  +P S+ DA +      +  +RTSFYLP DA+K LH+ S T   EVI+ LL+KF+VVD
Sbjct: 182 SSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVD 241

Query: 161 NPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFS 220
           +P+KFALF+R  + GQV  +KL   ++PL LRLLAGP  + LSFVLKEN++GEV WDAFS
Sbjct: 242 DPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFS 301

Query: 221 IPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEAL 257
           +PEL NFL IL++EE++ ++Q+ +KY   RQK++EAL
Sbjct: 302 MPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEAL 338


>gi|20149588 Ras association domain family 1 isoform A [Homo
           sapiens]
          Length = 340

 Score =  228 bits (580), Expect = 5e-60
 Identities = 116/217 (53%), Positives = 157/217 (72%)

Query: 41  NVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVP 100
           NV +PVE      +  EI+QKI  YN +  + L M L++DG+YTGFIKV LKL RPV+VP
Sbjct: 118 NVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVP 177

Query: 101 AGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVD 160
           +  +P S+ DA +      +  +RTSFYLP DA+K LH+ S T   EVI+ LL+KF+VVD
Sbjct: 178 SSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVD 237

Query: 161 NPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFS 220
           +P+KFALF+R  + GQV  +KL   ++PL LRLLAGP  + LSFVLKEN++GEV WDAFS
Sbjct: 238 DPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFS 297

Query: 221 IPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEAL 257
           +PEL NFL IL++EE++ ++Q+ +KY   RQK++EAL
Sbjct: 298 MPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEAL 334


>gi|30039698 Ras association (RalGDS/AF-6) domain family member 3
           [Homo sapiens]
          Length = 238

 Score =  213 bits (541), Expect = 2e-55
 Identities = 124/255 (48%), Positives = 172/255 (67%), Gaps = 24/255 (9%)

Query: 7   MSSGYCSLDEELEDCFFTAKTTFFRNA-QSKHLS-KNVCKPVEETQRPPTLQEIKQKIDS 64
           MSSGY SL+E+ ED FFTA+T+FFR A Q K  S +   +  +ET    + +EIK+K+  
Sbjct: 1   MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHK 60

Query: 65  YNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKR 124
           YN    + L M L+ +G YTGFIKV ++L +P        PQ+  ++ K   L+ +++  
Sbjct: 61  YNLAVTDKLKMTLNSNGIYTGFIKVQMELCKP--------PQTSPNSGK---LSPSSN-- 107

Query: 125 TSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSI 184
                    +  LHISST TV EVI+ LLKKF+V ++P KFAL+KR H++ QV   KLS 
Sbjct: 108 -------GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSD 160

Query: 185 ADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQK 244
            + PLYLRL+AGP T+ LSFVL+E+E G  EW+AFS+PELQNFL IL+KEE +++Q +++
Sbjct: 161 REHPLYLRLVAGPRTDTLSFVLREHEIG--EWEAFSLPELQNFLRILDKEEDEQLQNLKR 218

Query: 245 KYDKFRQKLEEALRE 259
           +Y  +RQKLEEALRE
Sbjct: 219 RYTAYRQKLEEALRE 233


>gi|25777680 Ras association domain family 1 isoform B [Homo
           sapiens]
          Length = 189

 Score =  211 bits (536), Expect = 7e-55
 Identities = 103/183 (56%), Positives = 139/183 (75%)

Query: 75  MKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAI 134
           M L++DG+YTGFIKV LKL RPV+VP+  +P S+ DA +      +  +RTSFYLP DA+
Sbjct: 1   MSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAV 60

Query: 135 KQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLL 194
           K LH+ S T   EVI+ LL+KF+VVD+P+KFALF+R  + GQV  +KL   ++PL LRLL
Sbjct: 61  KHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLL 120

Query: 195 AGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLE 254
           AGP  + LSFVLKEN++GEV WDAFS+PEL NFL IL++EE++ ++Q+ +KY   RQK++
Sbjct: 121 AGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQ 180

Query: 255 EAL 257
           EAL
Sbjct: 181 EAL 183


>gi|25777677 Ras association domain family 2 [Homo sapiens]
          Length = 326

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 44/148 (29%), Positives = 85/148 (57%), Gaps = 10/148 (6%)

Query: 124 RTSFYLPL-DAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKL 182
           +TS + P   ++  + I+ST T  +V++ LL KF + ++ ++FAL+  +H  G+   QKL
Sbjct: 179 KTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYV-VHTSGEK--QKL 235

Query: 183 SIADRPLYLRLLAGPDTEVLS-FVLKENETGEVEWDA-----FSIPELQNFLTILEKEEQ 236
              D PL  R+L GP  ++   F++++++  EV +D      F +P L++F+  L++EE 
Sbjct: 236 KATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEED 295

Query: 237 DKIQQVQKKYDKFRQKLEEALRESQGKP 264
            +++++ +KY   R  + + L E    P
Sbjct: 296 REVKKLMRKYTVLRLMIRQRLEEIAETP 323


>gi|7661964 Ras association domain family 2 [Homo sapiens]
          Length = 326

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 44/148 (29%), Positives = 85/148 (57%), Gaps = 10/148 (6%)

Query: 124 RTSFYLPL-DAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKL 182
           +TS + P   ++  + I+ST T  +V++ LL KF + ++ ++FAL+  +H  G+   QKL
Sbjct: 179 KTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYV-VHTSGEK--QKL 235

Query: 183 SIADRPLYLRLLAGPDTEVLS-FVLKENETGEVEWDA-----FSIPELQNFLTILEKEEQ 236
              D PL  R+L GP  ++   F++++++  EV +D      F +P L++F+  L++EE 
Sbjct: 236 KATDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEED 295

Query: 237 DKIQQVQKKYDKFRQKLEEALRESQGKP 264
            +++++ +KY   R  + + L E    P
Sbjct: 296 REVKKLMRKYTVLRLMIRQRLEEIAETP 323


>gi|23510360 Ras association domain family 4 [Homo sapiens]
          Length = 321

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 14/143 (9%)

Query: 124 RTSFYLPL-DAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKL 182
           +TS + P   ++  + ++ST T  +V+  LL KF V D P +FAL+  +H+ G+    KL
Sbjct: 177 KTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALY-IVHESGE--RTKL 233

Query: 183 SIADRPLYLRLLAGPDTEVLSFVLKENETG------EVEWDAFSIPELQNFLTILEKEEQ 236
              + PL  R+L GP  ++    L E + G        ++  F +P L +F+  L++EE+
Sbjct: 234 KDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEE 293

Query: 237 DKIQQVQKKYDKFR----QKLEE 255
            +I ++  K+   R    Q+LE+
Sbjct: 294 REIIKLTMKFQALRLTMLQRLEQ 316


>gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isoform b
           [Homo sapiens]
          Length = 369

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 39/130 (30%), Positives = 67/130 (51%), Gaps = 9/130 (6%)

Query: 125 TSFYLP-LDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLS 183
           TS ++P  ++  ++ ++S     EVI+ LL+KF + ++PQ FAL        Q   ++L 
Sbjct: 222 TSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ---RRLK 278

Query: 184 IADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDA-----FSIPELQNFLTILEKEEQDK 238
             D PL  RLL GP  +     L + +  E+  D      F    L++ L  L +EE+ +
Sbjct: 279 KTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKRE 338

Query: 239 IQQVQKKYDK 248
           IQ++  K++K
Sbjct: 339 IQRIVTKFNK 348


>gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isoform a
           [Homo sapiens]
          Length = 337

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 39/130 (30%), Positives = 67/130 (51%), Gaps = 9/130 (6%)

Query: 125 TSFYLP-LDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLS 183
           TS ++P  ++  ++ ++S     EVI+ LL+KF + ++PQ FAL        Q   ++L 
Sbjct: 190 TSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ---RRLK 246

Query: 184 IADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDA-----FSIPELQNFLTILEKEEQDK 238
             D PL  RLL GP  +     L + +  E+  D      F    L++ L  L +EE+ +
Sbjct: 247 KTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKRE 306

Query: 239 IQQVQKKYDK 248
           IQ++  K++K
Sbjct: 307 IQRIVTKFNK 316


>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 4 isoform 1 [Homo
           sapiens]
          Length = 1834

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 48/142 (33%), Positives = 73/142 (51%), Gaps = 26/142 (18%)

Query: 133 AIKQLHISSTTTVSEVIQGLLKKF---MVVDNPQKFALFKRIHKDGQVLFQKLSIADRPL 189
           A K + +SST T  +VI+ L +KF   M + +  K++L++ +H  G+   ++L I ++PL
Sbjct: 56  ATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYE-VHVSGE---RRLDIDEKPL 111

Query: 190 YLRLLAGPDTEVLSFVLKENETGEVEWDAFSI-PE-------LQNFLTILEKEEQDKIQQ 241
            ++L    D     FVLK NE   +   A S  PE       +QNF   L K+E      
Sbjct: 112 VVQLNWNKDDREGRFVLK-NENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKE------ 164

Query: 242 VQKKYDKFRQKLEEALRESQGK 263
             KK  K R+K  EALR++  K
Sbjct: 165 --KKEKKKREK--EALRQASDK 182


>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 4 isoform 2 [Homo
           sapiens]
          Length = 1651

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 46/142 (32%), Positives = 73/142 (51%), Gaps = 25/142 (17%)

Query: 133 AIKQLHISSTTTVSEVIQGLLKKF---MVVDNPQKFALFKRIHKDGQVLFQKLSIADRPL 189
           A K + +SST T  +VI+ L +KF   M + +  K++L++ +H  G+   ++L I ++PL
Sbjct: 56  ATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYE-VHVSGE---RRLDIDEKPL 111

Query: 190 YLRLLAGPDTEVLSFVLK-ENETGEVEWDAFSIPE-------LQNFLTILEKEEQDKIQQ 241
            ++L    D     FVLK EN+    +    + PE       +QNF   L K+E      
Sbjct: 112 VVQLNWNKDDREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKE------ 165

Query: 242 VQKKYDKFRQKLEEALRESQGK 263
             KK  K R+K  EALR++  K
Sbjct: 166 --KKEKKKREK--EALRQASDK 183


>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 4 isoform 3 [Homo
           sapiens]
          Length = 1612

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 48/142 (33%), Positives = 73/142 (51%), Gaps = 26/142 (18%)

Query: 133 AIKQLHISSTTTVSEVIQGLLKKF---MVVDNPQKFALFKRIHKDGQVLFQKLSIADRPL 189
           A K + +SST T  +VI+ L +KF   M + +  K++L++ +H  G+   ++L I ++PL
Sbjct: 56  ATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYE-VHVSGE---RRLDIDEKPL 111

Query: 190 YLRLLAGPDTEVLSFVLKENETGEVEWDAFSI-PE-------LQNFLTILEKEEQDKIQQ 241
            ++L    D     FVLK NE   +   A S  PE       +QNF   L K+E      
Sbjct: 112 VVQLNWNKDDREGRFVLK-NENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKE------ 164

Query: 242 VQKKYDKFRQKLEEALRESQGK 263
             KK  K R+K  EALR++  K
Sbjct: 165 --KKEKKKREK--EALRQASDK 182


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 36.2 bits (82), Expect = 0.030
 Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 29/243 (11%)

Query: 40   KNVCKPVEETQRPPTLQEIKQKIDSYNT--REKNCLGMKLSEDG-TYTGFIKVHLK-LRR 95
            +N+ K ++E Q    L E+ + + S+ +   EK    +++ E+  T    ++  LK L  
Sbjct: 2213 ENLTKQIQEKQGQ--LSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNE 2270

Query: 96   PVTVPAGIRP------QSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVI 149
             V    G +       QS+   I+E +    + ++    L  D  KQL +      SE  
Sbjct: 2271 AVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHH 2330

Query: 150  QGLLK--------KFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEV 201
              LLK        +  +    Q+ A  +  +  G+V   K  I      LR   G + +V
Sbjct: 2331 ADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLR---GLELDV 2387

Query: 202  LSFVL-KENETGEVEWDAFSIPELQ----NFLTILEKEEQDKIQQVQKKYDKFRQKLEEA 256
            ++    KEN T E++ +   I EL+    +F  IL+++EQ+K+ Q+++K     + L+  
Sbjct: 2388 VTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKV-QMKEKSSTAMEMLQTQ 2446

Query: 257  LRE 259
            L+E
Sbjct: 2447 LKE 2449


>gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
           isoform 2 [Homo sapiens]
          Length = 686

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 38/167 (22%), Positives = 71/167 (42%), Gaps = 11/167 (6%)

Query: 104 RPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTV---SEVIQGLLKKFMVVD 160
           R     D ++EV  A    + T  Y  +DA+ +L       +   + + Q LLKK   + 
Sbjct: 27  RQHDTQDLLEEVLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLT 86

Query: 161 NPQKFA--LFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTE---VLSFVLKENETGEVE 215
              +      + I ++   L  +LS+ D  L     A  ++E   V S  LK NE+    
Sbjct: 87  ERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSV 146

Query: 216 WDAFSIPELQNFLTILEKEE---QDKIQQVQKKYDKFRQKLEEALRE 259
            + F +  LQ  L  LE+E    + +  Q++ +   + +K ++ + +
Sbjct: 147 QNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVND 193


>gi|178056552 non-SMC condensin I complex, subunit D2 [Homo sapiens]
          Length = 1401

 Score = 33.1 bits (74), Expect = 0.26
 Identities = 30/112 (26%), Positives = 57/112 (50%), Gaps = 22/112 (19%)

Query: 30   FRNAQSKHLSKNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKV 89
            FR ++++   +++   V  +Q P T + +++ +D+++     C G KLS++  ++ F+ V
Sbjct: 1214 FRTSRTERQQRDLAYCV--SQLPLTERGLRKMLDNFD-----CFGDKLSDESIFSAFLSV 1266

Query: 90   HLKLRRPVTVPAGIRPQ--SIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHI 139
              KLRR      G +P+  +I D  ++   A  T         LD IK+L I
Sbjct: 1267 VGKLRR------GAKPEGKAIIDEFEQKLRACHT-------RGLDGIKELEI 1305


>gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens]
          Length = 800

 Score = 33.1 bits (74), Expect = 0.26
 Identities = 17/49 (34%), Positives = 31/49 (63%), Gaps = 2/49 (4%)

Query: 213 EVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQ 261
           EV+ D   I + + F+T   KE++  + ++Q+K+ K  +KLE  LRE++
Sbjct: 433 EVKKDTEDINKPKKFMTF--KEKRKSLSRMQRKWKKAEEKLERELREAE 479


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 31.2 bits (69), Expect = 0.98
 Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 13/154 (8%)

Query: 112 IKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRI 171
           IKE N A     +      LD  KQL         E  + LLK+ +++D      + ++I
Sbjct: 170 IKEENAAEDKRNKAKAQYYLDLEKQLE-EQEKKKQEAYEQLLKEKLMIDE-----IVRKI 223

Query: 172 HKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTIL 231
           +++ Q+  Q+  +       R +     E   +  K+ E  E+E +   I E  N     
Sbjct: 224 YEEDQLEKQQ-KLEKMNAMRRYIEEFQKEQALWRKKKRE--EMEEENRKIIEFANMQQQR 280

Query: 232 EKEEQDKIQQVQKK----YDKFRQKLEEALRESQ 261
           E++   K+Q+ ++K     +   QKLEE LR+ +
Sbjct: 281 EEDRMAKVQENEEKRLQLQNALTQKLEEMLRQRE 314


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
            1 [Homo sapiens]
          Length = 1412

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 1/58 (1%)

Query: 206  LKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGK 263
            L E +  E+E +   + +    L++L KE+  ++  + +K D+  + LEEALR SQ K
Sbjct: 1032 LNEKQKMELEQNVVLVQQQSKELSVL-KEKMAQMSSLVEKKDRELKALEEALRASQEK 1088


>gi|217416354 sphingosine kinase type 1-interacting protein isoform
           1 [Homo sapiens]
          Length = 1700

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 9/56 (16%)

Query: 32  NAQSKHLSKNVCKPVEETQRPPTL-------QEIKQKIDSYNTREK-NCLGMKLSE 79
           + +S H S+N C+   E QR PT+       QE ++ I   NT+EK NC   +++E
Sbjct: 842 DTKSPHHSENECRASSEGQRSPTVSQSRSGSQEAEESIHP-NTQEKYNCATSRINE 896


>gi|217416352 sphingosine kinase type 1-interacting protein isoform
           2 [Homo sapiens]
          Length = 1671

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 9/56 (16%)

Query: 32  NAQSKHLSKNVCKPVEETQRPPTL-------QEIKQKIDSYNTREK-NCLGMKLSE 79
           + +S H S+N C+   E QR PT+       QE ++ I   NT+EK NC   +++E
Sbjct: 842 DTKSPHHSENECRASSEGQRSPTVSQSRSGSQEAEESIHP-NTQEKYNCATSRINE 896


>gi|169167074 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 309

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 12/31 (38%), Positives = 23/31 (74%)

Query: 221 IPELQNFLTILEKEEQDKIQQVQKKYDKFRQ 251
           I E+QN +  L +++ ++I +V++KY+K RQ
Sbjct: 74  IDEIQNEIDRLNEQDNEEILKVEQKYNKLRQ 104


>gi|169166810 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 309

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 12/31 (38%), Positives = 23/31 (74%)

Query: 221 IPELQNFLTILEKEEQDKIQQVQKKYDKFRQ 251
           I E+QN +  L +++ ++I +V++KY+K RQ
Sbjct: 74  IDEIQNEIDRLNEQDNEEILKVEQKYNKLRQ 104


>gi|169166302 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 296

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 12/31 (38%), Positives = 23/31 (74%)

Query: 221 IPELQNFLTILEKEEQDKIQQVQKKYDKFRQ 251
           I E+QN +  L +++ ++I +V++KY+K RQ
Sbjct: 61  IDEIQNEIDRLNEQDNEEILKVEQKYNKLRQ 91


>gi|66392146 RNA U, small nuclear RNA export adaptor
           (phosphorylation regulated) [Homo sapiens]
          Length = 394

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 8/96 (8%)

Query: 28  TFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFI 87
           T  R+ QS+  +  + K + +  +  T +++ +++D Y    K  +G K  E+G      
Sbjct: 142 TIDRSRQSETYNYLLAKKLRKESQEHT-KDLDKELDEYMHGGKK-MGSKEEENG------ 193

Query: 88  KVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDK 123
           + HLK +RPV    G RP+  Y    E+    + +K
Sbjct: 194 QGHLKRKRPVKDRLGNRPEMNYKGRYEITAEDSQEK 229


>gi|21396489 mitochondrial lon peptidase 1 [Homo sapiens]
          Length = 959

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 8/71 (11%)

Query: 184 IADRPLYLR----LLAGPDTEVLSFVLKENETGEVEWDAFSIP----ELQNFLTILEKEE 235
           + D P+YL      L G ++  L  VL+E    +  + A S+     EL      L +E 
Sbjct: 324 VVDNPIYLSDMGAALTGAESHELQDVLEETNIPKRLYKALSLLKKEFELSKLQQRLGREV 383

Query: 236 QDKIQQVQKKY 246
           ++KI+Q  +KY
Sbjct: 384 EEKIKQTHRKY 394


>gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 12/31 (38%), Positives = 23/31 (74%)

Query: 221 IPELQNFLTILEKEEQDKIQQVQKKYDKFRQ 251
           I E+QN +  L +++ ++I +V++KY+K RQ
Sbjct: 58  IDEVQNEIDRLNEQDSEEILKVEQKYNKLRQ 88


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,741,699
Number of Sequences: 37866
Number of extensions: 415995
Number of successful extensions: 2031
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1970
Number of HSP's gapped (non-prelim): 72
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.