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Search of human proteins with 124028517
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124028517 hematopoietic transcription factor PU.1 isoform 2
[Homo sapiens]
(270 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124028517 hematopoietic transcription factor PU.1 isoform 2 [... 572 e-164
gi|124028521 hematopoietic transcription factor PU.1 isoform 1 [... 568 e-162
gi|61888836 Spi-B transcription factor (Spi-1/PU.1 related) [Hom... 174 6e-44
gi|22748707 Spi-C transcription factor (Spi-1/PU.1 related) [Hom... 121 7e-28
gi|34452721 GA binding protein transcription factor, alpha subun... 64 1e-10
gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens] 62 5e-10
gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens] 62 5e-10
gi|6912580 SAM pointed domain containing ets transcription facto... 57 2e-08
gi|11496882 ELK4 protein isoform b [Homo sapiens] 56 4e-08
gi|41872448 ELK4 protein isoform a [Homo sapiens] 56 4e-08
gi|4885221 v-ets erythroblastosis virus E26 oncogene homolog 2 [... 55 5e-08
gi|166362732 ELK1 protein [Homo sapiens] 54 1e-07
gi|166362730 ELK1 protein [Homo sapiens] 54 1e-07
gi|27436883 ets homologous factor [Homo sapiens] 54 1e-07
gi|8923789 FEV (ETS oncogene family) [Homo sapiens] 53 2e-07
gi|27363484 E74-like factor 1 (ets domain transcription factor) ... 53 3e-07
gi|223941929 E74-like factor 1 (ets domain transcription factor)... 53 3e-07
gi|7110593 Friend leukemia virus integration 1 [Homo sapiens] 52 5e-07
gi|42544172 E74-like factor 2 (ets domain transcription factor) ... 52 5e-07
gi|6857816 E74-like factor 2 (ets domain transcription factor) i... 52 5e-07
gi|153791178 ets variant gene 2 [Homo sapiens] 51 9e-07
gi|187608767 E74-like factor 4 [Homo sapiens] 51 1e-06
gi|4503555 E74-like factor 4 [Homo sapiens] 51 1e-06
gi|253683437 ets variant gene 1 isoform f [Homo sapiens] 51 1e-06
gi|253683435 ets variant gene 1 isoform e [Homo sapiens] 51 1e-06
gi|253683433 ets variant gene 1 isoform d [Homo sapiens] 51 1e-06
gi|253683431 ets variant gene 1 isoform c [Homo sapiens] 51 1e-06
gi|253683429 ets variant gene 1 isoform c [Homo sapiens] 51 1e-06
gi|31742534 ets variant gene 1 isoform a [Homo sapiens] 51 1e-06
gi|219689118 v-ets erythroblastosis virus E26 oncogene homolog 1... 51 1e-06
>gi|124028517 hematopoietic transcription factor PU.1 isoform 2
[Homo sapiens]
Length = 270
Score = 572 bits (1475), Expect = e-164
Identities = 270/270 (100%), Positives = 270/270 (100%)
Query: 1 MLQACKMEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHS 60
MLQACKMEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHS
Sbjct: 1 MLQACKMEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHS 60
Query: 61 EFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQ 120
EFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQ
Sbjct: 61 EFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQ 120
Query: 121 YPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLL 180
YPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLL
Sbjct: 121 YPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLL 180
Query: 181 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE 240
RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE
Sbjct: 181 RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE 240
Query: 241 VKKVKKKLTYQFSGEVLGRGGLAERRHPPH 270
VKKVKKKLTYQFSGEVLGRGGLAERRHPPH
Sbjct: 241 VKKVKKKLTYQFSGEVLGRGGLAERRHPPH 270
>gi|124028521 hematopoietic transcription factor PU.1 isoform 1
[Homo sapiens]
Length = 271
Score = 568 bits (1463), Expect = e-162
Identities = 270/271 (99%), Positives = 270/271 (99%), Gaps = 1/271 (0%)
Query: 1 MLQACKMEGFPLVPP-PSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 59
MLQACKMEGFPLVPP PSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH
Sbjct: 1 MLQACKMEGFPLVPPQPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVH 60
Query: 60 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL 119
SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL
Sbjct: 61 SEFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCL 120
Query: 120 QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL 179
QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL
Sbjct: 121 QYPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDL 180
Query: 180 LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG 239
LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG
Sbjct: 181 LRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTG 240
Query: 240 EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH 270
EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH
Sbjct: 241 EVKKVKKKLTYQFSGEVLGRGGLAERRHPPH 271
>gi|61888836 Spi-B transcription factor (Spi-1/PU.1 related) [Homo
sapiens]
Length = 262
Score = 174 bits (442), Expect = 6e-44
Identities = 117/267 (43%), Positives = 150/267 (56%), Gaps = 25/267 (9%)
Query: 2 LQACKMEG--FPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFH--PHH 57
L+A +++G F + P D V YD D + H YP D E D WD+ P
Sbjct: 4 LEAAQLDGPHFSCLYP---DGVFYDLDSCK---HSSYP----DSEGAPDSLWDWTVAPPV 53
Query: 58 VHSEFESF--AENNFTELQSVQ---PPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVS 112
+ +E+F A F+ Q+ Q P ++EL P +P +P+
Sbjct: 54 PATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQ 113
Query: 113 YL-PRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEAD-GLEPGPGLLPGETGSKKKI 170
L P YPS S+EE+ SP LEVSD E+D L GP E G++KK+
Sbjct: 114 TLVPPAYAPYPS----PVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKL 169
Query: 171 RLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMAR 230
RLYQFLL LL GDM++ +WWV+ G FQFSSKHKE LA RWG QKGNRK+MTYQK+AR
Sbjct: 170 RLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLAR 229
Query: 231 ALRNYGKTGEVKKVKKKLTYQFSGEVL 257
ALRNY KTGE++KVK+KLTYQF +L
Sbjct: 230 ALRNYAKTGEIRKVKRKLTYQFDSALL 256
>gi|22748707 Spi-C transcription factor (Spi-1/PU.1 related) [Homo
sapiens]
Length = 248
Score = 121 bits (303), Expect = 7e-28
Identities = 60/104 (57%), Positives = 78/104 (75%), Gaps = 1/104 (0%)
Query: 157 PGLLPGETGS-KKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGI 215
P LL + G +KK+RL+++L + L + +M I WVDK KG FQF SK+KE LA WG
Sbjct: 97 PTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGK 156
Query: 216 QKGNRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGR 259
+KGNRK MTYQKMARALRNYG++GE+ K+++KLTYQFS +L R
Sbjct: 157 RKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQR 200
>gi|34452721 GA binding protein transcription factor, alpha subunit
[Homo sapiens]
Length = 454
Score = 63.9 bits (154), Expect = 1e-10
Identities = 52/178 (29%), Positives = 90/178 (50%), Gaps = 17/178 (9%)
Query: 79 PQLQQLYRHMELEQMHVLDTPMVPPHP--SLGHQVSYLPRMCLQY-PSLSPAQPSSDEEE 135
P+ + L+ H+EL + +VL + + ++ V +P P+ SS +
Sbjct: 235 PRGEILWSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAA 294
Query: 136 GERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKD 195
+++P + D + G TG+ +I+L+QFLL+LL D +D I WV D
Sbjct: 295 KVQRAPRISGEDRSSPG---------NRTGNNGQIQLWQFLLELLTDKDARDCISWVG-D 344
Query: 196 KGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQF 252
+G F+ + E +A +WG Q+ N+ M Y+K++RALR Y + KV+ K+ Y+F
Sbjct: 345 EGEFKLN--QPELVAQKWG-QRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKF 399
>gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]
Length = 265
Score = 62.0 bits (149), Expect = 5e-10
Identities = 37/94 (39%), Positives = 57/94 (60%), Gaps = 4/94 (4%)
Query: 166 SKKKIRLYQFLLDLLRSGDMKDSIW-WVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMT 224
S + L++F+ DLL S + I W D+++G F+ EALA WG +K N +MT
Sbjct: 169 SLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKS--EALAKMWGQRKKN-DRMT 225
Query: 225 YQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLG 258
Y+K++RALR Y KTG +++V ++L Y+F G
Sbjct: 226 YEKLSRALRYYYKTGILERVDRRLVYKFGKNAHG 259
>gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]
Length = 255
Score = 62.0 bits (149), Expect = 5e-10
Identities = 37/94 (39%), Positives = 57/94 (60%), Gaps = 4/94 (4%)
Query: 166 SKKKIRLYQFLLDLLRSGDMKDSIW-WVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMT 224
S + L++F+ DLL S + I W D+++G F+ EALA WG +K N +MT
Sbjct: 159 SLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKS--EALAKMWGQRKKN-DRMT 215
Query: 225 YQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLG 258
Y+K++RALR Y KTG +++V ++L Y+F G
Sbjct: 216 YEKLSRALRYYYKTGILERVDRRLVYKFGKNAHG 249
>gi|6912580 SAM pointed domain containing ets transcription factor
[Homo sapiens]
Length = 335
Score = 56.6 bits (135), Expect = 2e-08
Identities = 34/90 (37%), Positives = 54/90 (60%), Gaps = 6/90 (6%)
Query: 166 SKKKIRLYQFLLDLL-RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMT 224
S + I L+QFL +LL + I W++K+KG F+ + +A WGI+K NR M
Sbjct: 245 SGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQ--VARLWGIRK-NRPAMN 301
Query: 225 YQKMARALRNYGKTGEVKK--VKKKLTYQF 252
Y K++R++R Y K G ++K + ++L YQF
Sbjct: 302 YDKLSRSIRQYYKKGIIRKPDISQRLVYQF 331
>gi|11496882 ELK4 protein isoform b [Homo sapiens]
Length = 405
Score = 55.8 bits (133), Expect = 4e-08
Identities = 35/84 (41%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 170 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 229
I L+QFLL LL+ K I W D QF E +A WGI+K N+ M Y K++
Sbjct: 5 ITLWQFLLQLLQKPQNKHMICWTSNDG---QFKLLQAEEVARLWGIRK-NKPNMNYDKLS 60
Query: 230 RALRNYGKTGEVKKVK-KKLTYQF 252
RALR Y +KKV +K Y+F
Sbjct: 61 RALRYYYVKNIIKKVNGQKFVYKF 84
>gi|41872448 ELK4 protein isoform a [Homo sapiens]
Length = 431
Score = 55.8 bits (133), Expect = 4e-08
Identities = 35/84 (41%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 170 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 229
I L+QFLL LL+ K I W D QF E +A WGI+K N+ M Y K++
Sbjct: 5 ITLWQFLLQLLQKPQNKHMICWTSNDG---QFKLLQAEEVARLWGIRK-NKPNMNYDKLS 60
Query: 230 RALRNYGKTGEVKKVK-KKLTYQF 252
RALR Y +KKV +K Y+F
Sbjct: 61 RALRYYYVKNIIKKVNGQKFVYKF 84
>gi|4885221 v-ets erythroblastosis virus E26 oncogene homolog 2
[Homo sapiens]
Length = 469
Score = 55.5 bits (132), Expect = 5e-08
Identities = 47/162 (29%), Positives = 72/162 (44%), Gaps = 19/162 (11%)
Query: 92 QMHVLDTPMVPPHPSLGHQVSYLPRMCLQYPSLSPAQPSSDEEEGERQSPPLEVSDGEAD 151
Q +LD VP S S +CL P++S + + Q P+ +
Sbjct: 299 QSSLLDVQRVPSFESFEDDCSQ--SLCLNKPTMSFKDYIQERSDPVEQGKPVIPA----- 351
Query: 152 GLEPGPGLLPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAH 211
+L G TGS I+L+QFLL+LL + I W ++F + +A
Sbjct: 352 ------AVLAGFTGSGP-IQLWQFLLELLSDKSCQSFISWTGDG---WEFKLADPDEVAR 401
Query: 212 RWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQF 252
RWG +K N+ KM Y+K++R LR Y + K K+ Y+F
Sbjct: 402 RWGKRK-NKPKMNYEKLSRGLRYYYDKNIIHKTSGKRYVYRF 442
>gi|166362732 ELK1 protein [Homo sapiens]
Length = 428
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 170 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 229
+ L+QFLL LLR I W +D G F+ E +A WG++K N+ M Y K++
Sbjct: 5 VTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVD--AEEVARLWGLRK-NKTNMNYDKLS 61
Query: 230 RALRNYGKTGEVKKVK-KKLTYQF 252
RALR Y ++KV +K Y+F
Sbjct: 62 RALRYYYDKNIIRKVSGQKFVYKF 85
>gi|166362730 ELK1 protein [Homo sapiens]
Length = 428
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 170 IRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMA 229
+ L+QFLL LLR I W +D G F+ E +A WG++K N+ M Y K++
Sbjct: 5 VTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVD--AEEVARLWGLRK-NKTNMNYDKLS 61
Query: 230 RALRNYGKTGEVKKVK-KKLTYQF 252
RALR Y ++KV +K Y+F
Sbjct: 62 RALRYYYDKNIIRKVSGQKFVYKF 85
>gi|27436883 ets homologous factor [Homo sapiens]
Length = 300
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 5/89 (5%)
Query: 172 LYQFLLDLLRSGDMKDS-IWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMAR 230
L++F+ D+L + D I W D+ +G F+F EA+A WG +K N MTY+K++R
Sbjct: 209 LWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKS--EAVAQLWG-KKKNNSSMTYEKLSR 265
Query: 231 ALRNYGKTGEVKKVK-KKLTYQFSGEVLG 258
A+R Y K +++V ++L Y+F G
Sbjct: 266 AMRYYYKREILERVDGRRLVYKFGKNARG 294
>gi|8923789 FEV (ETS oncogene family) [Homo sapiens]
Length = 238
Score = 53.1 bits (126), Expect = 2e-07
Identities = 45/131 (34%), Positives = 63/131 (48%), Gaps = 12/131 (9%)
Query: 142 PLEVSDGE-ADGLEPGPG-LLPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTF 199
P V DG DG P G L P +I+L+QFLL+LL I W + G
Sbjct: 17 PDPVGDGLFKDGKNPSWGPLSPAVQKGSGQIQLWQFLLELLADRANAGCIAW---EGGHG 73
Query: 200 QFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQFSGEVLG 258
+F + +A RWG +K ++ M Y K++RALR Y + KV K+ Y+F +
Sbjct: 74 EFKLTDPDEVARRWGERK-SKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFDFQ--- 129
Query: 259 RGGLAERRHPP 269
GLA+ PP
Sbjct: 130 --GLAQACQPP 138
>gi|27363484 E74-like factor 1 (ets domain transcription factor)
isoform a [Homo sapiens]
Length = 619
Score = 52.8 bits (125), Expect = 3e-07
Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 10/130 (7%)
Query: 125 SPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLLRS-G 183
SP QP ++G + PP S + + G I L++FLL LL+
Sbjct: 168 SPEQPK--RKKGRKTKPPRPDSPATTPNISVKK---KNKDGKGNTIYLWEFLLALLQDKA 222
Query: 184 DMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKK 243
I W ++KG F+ +A++ WG K N+ M Y+ M RALR Y + G + K
Sbjct: 223 TCPKYIKWTQREKGIFKLVDS--KAVSRLWGKHK-NKPDMNYETMGRALRYYYQRGILAK 279
Query: 244 VK-KKLTYQF 252
V+ ++L YQF
Sbjct: 280 VEGQRLVYQF 289
>gi|223941929 E74-like factor 1 (ets domain transcription factor)
isoform b [Homo sapiens]
Length = 595
Score = 52.8 bits (125), Expect = 3e-07
Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 10/130 (7%)
Query: 125 SPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLLRS-G 183
SP QP ++G + PP S + + G I L++FLL LL+
Sbjct: 144 SPEQPK--RKKGRKTKPPRPDSPATTPNISVKK---KNKDGKGNTIYLWEFLLALLQDKA 198
Query: 184 DMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKK 243
I W ++KG F+ +A++ WG K N+ M Y+ M RALR Y + G + K
Sbjct: 199 TCPKYIKWTQREKGIFKLVDS--KAVSRLWGKHK-NKPDMNYETMGRALRYYYQRGILAK 255
Query: 244 VK-KKLTYQF 252
V+ ++L YQF
Sbjct: 256 VEGQRLVYQF 265
>gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]
Length = 452
Score = 52.0 bits (123), Expect = 5e-07
Identities = 44/144 (30%), Positives = 68/144 (47%), Gaps = 17/144 (11%)
Query: 121 YPSLSPAQPSSDEEEGERQSPPL----EVSDGEADGLEPGPGLLPGETGSKK------KI 170
Y S+ ++ G +SPPL +S +P P + G T S+ +I
Sbjct: 222 YDSVRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQI 281
Query: 171 RLYQFLLDLLRSGDMKDSIWWVDKDKGTF-QFSSKHKEALAHRWGIQKGNRKKMTYQKMA 229
+L+QFLL+LL I W +GT +F + +A RWG +K ++ M Y K++
Sbjct: 282 QLWQFLLELLSDSANASCITW----EGTNGEFKMTDPDEVARRWGERK-SKPNMNYDKLS 336
Query: 230 RALRNYGKTGEVKKVK-KKLTYQF 252
RALR Y + KV K+ Y+F
Sbjct: 337 RALRYYYDKNIMTKVHGKRYAYKF 360
>gi|42544172 E74-like factor 2 (ets domain transcription factor)
isoform 1 [Homo sapiens]
Length = 581
Score = 52.0 bits (123), Expect = 5e-07
Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 13/100 (13%)
Query: 163 ETGSKKKIR--------LYQFLLDLLRSGDMKDS-IWWVDKDKGTFQFSSKHKEALAHRW 213
E G KKK R L++FLLDLL+ + I W ++KG F+ +A++ W
Sbjct: 181 ELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDS--KAVSKLW 238
Query: 214 GIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQF 252
G K N+ M Y+ M RALR Y + G + KV+ ++L YQF
Sbjct: 239 GKHK-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 277
>gi|6857816 E74-like factor 2 (ets domain transcription factor)
isoform 2 [Homo sapiens]
Length = 533
Score = 52.0 bits (123), Expect = 5e-07
Identities = 38/100 (38%), Positives = 55/100 (55%), Gaps = 13/100 (13%)
Query: 163 ETGSKKKIR--------LYQFLLDLLRSGDMKDS-IWWVDKDKGTFQFSSKHKEALAHRW 213
E G KKK R L++FLLDLL+ + I W ++KG F+ +A++ W
Sbjct: 133 ELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDS--KAVSKLW 190
Query: 214 GIQKGNRKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQF 252
G K N+ M Y+ M RALR Y + G + KV+ ++L YQF
Sbjct: 191 GKHK-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 229
>gi|153791178 ets variant gene 2 [Homo sapiens]
Length = 342
Score = 51.2 bits (121), Expect = 9e-07
Identities = 32/95 (33%), Positives = 50/95 (52%), Gaps = 5/95 (5%)
Query: 163 ETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKK 222
+T + I+L+QFLL+LL G I W + +F + +A WG +K +
Sbjct: 234 KTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSR---EFQLCDPKEVARLWGERK-RKPG 289
Query: 223 MTYQKMARALRNYGKTGEVKKV-KKKLTYQFSGEV 256
M Y+K++R LR Y + V+K +K TY+F G V
Sbjct: 290 MNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRV 324
>gi|187608767 E74-like factor 4 [Homo sapiens]
Length = 663
Score = 50.8 bits (120), Expect = 1e-06
Identities = 34/90 (37%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Query: 165 GSKKKIRLYQFLLDLLRSGDMKDS-IWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKM 223
G I L++FLL LL+ + I W ++KG F+ +A++ WG QK N+ M
Sbjct: 204 GKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDS--KAVSKLWGKQK-NKPDM 260
Query: 224 TYQKMARALRNYGKTGEVKKVK-KKLTYQF 252
Y+ M RALR Y + G + KV+ ++L YQF
Sbjct: 261 NYETMGRALRYYYQRGILAKVEGQRLVYQF 290
>gi|4503555 E74-like factor 4 [Homo sapiens]
Length = 663
Score = 50.8 bits (120), Expect = 1e-06
Identities = 34/90 (37%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Query: 165 GSKKKIRLYQFLLDLLRSGDMKDS-IWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKM 223
G I L++FLL LL+ + I W ++KG F+ +A++ WG QK N+ M
Sbjct: 204 GKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDS--KAVSKLWGKQK-NKPDM 260
Query: 224 TYQKMARALRNYGKTGEVKKVK-KKLTYQF 252
Y+ M RALR Y + G + KV+ ++L YQF
Sbjct: 261 NYETMGRALRYYYQRGILAKVEGQRLVYQF 290
>gi|253683437 ets variant gene 1 isoform f [Homo sapiens]
Length = 374
Score = 50.8 bits (120), Expect = 1e-06
Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 13/135 (9%)
Query: 127 AQPSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLD 178
A PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+
Sbjct: 181 AHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVA 240
Query: 179 LLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKT 238
LL I W + +F E +A RWGIQK NR M Y K++R+LR Y +
Sbjct: 241 LLDDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEK 296
Query: 239 GEVKKVK-KKLTYQF 252
G ++KV ++ Y+F
Sbjct: 297 GIMQKVAGERYVYKF 311
>gi|253683435 ets variant gene 1 isoform e [Homo sapiens]
Length = 419
Score = 50.8 bits (120), Expect = 1e-06
Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 13/135 (9%)
Query: 127 AQPSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLD 178
A PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+
Sbjct: 226 AHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVA 285
Query: 179 LLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKT 238
LL I W + +F E +A RWGIQK NR M Y K++R+LR Y +
Sbjct: 286 LLDDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEK 341
Query: 239 GEVKKVK-KKLTYQF 252
G ++KV ++ Y+F
Sbjct: 342 GIMQKVAGERYVYKF 356
>gi|253683433 ets variant gene 1 isoform d [Homo sapiens]
Length = 437
Score = 50.8 bits (120), Expect = 1e-06
Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 13/135 (9%)
Query: 127 AQPSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLD 178
A PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+
Sbjct: 244 AHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVA 303
Query: 179 LLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKT 238
LL I W + +F E +A RWGIQK NR M Y K++R+LR Y +
Sbjct: 304 LLDDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEK 359
Query: 239 GEVKKVK-KKLTYQF 252
G ++KV ++ Y+F
Sbjct: 360 GIMQKVAGERYVYKF 374
>gi|253683431 ets variant gene 1 isoform c [Homo sapiens]
Length = 459
Score = 50.8 bits (120), Expect = 1e-06
Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 13/135 (9%)
Query: 127 AQPSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLD 178
A PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+
Sbjct: 266 AHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVA 325
Query: 179 LLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKT 238
LL I W + +F E +A RWGIQK NR M Y K++R+LR Y +
Sbjct: 326 LLDDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEK 381
Query: 239 GEVKKVK-KKLTYQF 252
G ++KV ++ Y+F
Sbjct: 382 GIMQKVAGERYVYKF 396
>gi|253683429 ets variant gene 1 isoform c [Homo sapiens]
Length = 459
Score = 50.8 bits (120), Expect = 1e-06
Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 13/135 (9%)
Query: 127 AQPSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLD 178
A PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+
Sbjct: 266 AHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVA 325
Query: 179 LLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKT 238
LL I W + +F E +A RWGIQK NR M Y K++R+LR Y +
Sbjct: 326 LLDDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEK 381
Query: 239 GEVKKVK-KKLTYQF 252
G ++KV ++ Y+F
Sbjct: 382 GIMQKVAGERYVYKF 396
>gi|31742534 ets variant gene 1 isoform a [Homo sapiens]
Length = 477
Score = 50.8 bits (120), Expect = 1e-06
Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 13/135 (9%)
Query: 127 AQPSSDE----EEGERQ--SPPLEVSDGEADGLEPGPGLL-PGETGSKK-KIRLYQFLLD 178
A PS E E+G RQ V + ++ PG+ G T ++ ++L+QFL+
Sbjct: 284 AHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVA 343
Query: 179 LLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKT 238
LL I W + +F E +A RWGIQK NR M Y K++R+LR Y +
Sbjct: 344 LLDDPSNSHFIAWTGRG---MEFKLIEPEEVARRWGIQK-NRPAMNYDKLSRSLRYYYEK 399
Query: 239 GEVKKVK-KKLTYQF 252
G ++KV ++ Y+F
Sbjct: 400 GIMQKVAGERYVYKF 414
>gi|219689118 v-ets erythroblastosis virus E26 oncogene homolog 1
isoform 1 [Homo sapiens]
Length = 485
Score = 50.8 bits (120), Expect = 1e-06
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 6/94 (6%)
Query: 160 LPGETGSKKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGN 219
L G TGS I+L+QFLL+LL + I W ++F + +A RWG +K N
Sbjct: 370 LAGYTGSGP-IQLWQFLLELLTDKSCQSFISWTGDG---WEFKLSDPDEVARRWGKRK-N 424
Query: 220 RKKMTYQKMARALRNYGKTGEVKKVK-KKLTYQF 252
+ KM Y+K++R LR Y + K K+ Y+F
Sbjct: 425 KPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRF 458
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,427,296
Number of Sequences: 37866
Number of extensions: 710711
Number of successful extensions: 2271
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 2199
Number of HSP's gapped (non-prelim): 137
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.