Guide to the Human Genome
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Name: ARHGEF3 Sequence: fasta or formatted (558aa) NCBI GI: 190885495
Description:

Rho guanine nucleotide exchange factor 3 isoform 1

Referenced in:

Rho and Rac

Other entries for this name:
alt prot [532aa] Rho guanine nucleotide exchange factor 3 isoform 2
alt prot [526aa] Rho guanine nucleotide exchange factor 3 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.1         23           2
 C cysteine            2.9         16           2
 D aspartate           6.1         34           1
 E glutamate           7.9         44           2
 F phenylalanine       3.4         19           2
 G glycine             4.3         24           2
 H histidine           2.2         12           1
 I isoleucine          4.1         23           2
 K lysine              6.1         34           2
 L leucine            11.5         64           3
 M methionine          1.8         10           1
 N asparagine          5.2         29           2
 P proline             4.7         26           2
 Q glutamine           6.6         37           2
 R arginine            7.3         41           2
 S serine             10.2         57           2
 T threonine           4.3         24           2
 V valine              4.7         26           1
 W tryptophan          1.1          6           1
 Y tyrosine            1.6          9           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rho guanine nucleotide exchange factor 3 isoform 1 ... 
ARHGEF3               0.881   Rho guanine nucleotide exchange factor 3 isoform 3 [H...
ARHGEF3               0.879   Rho guanine nucleotide exchange factor 3 isoform 2 ...
NET1                  0.504   neuroepithelial cell transforming gene 1 isoform 1 ...
NET1                  0.482   neuroepithelial cell transforming gene 1 isoform 2 [...
ITSN1                 0.088   intersectin 1 isoform ITSN-l 
ITSN2                 0.075   intersectin 2 isoform 3 
ITSN2                 0.075   intersectin 2 isoform 1 
DNMBP                 0.063   dynamin binding protein 
ARHGEF11              0.058   Rho guanine nucleotide exchange factor (GEF) 11 isof...
ARHGEF11              0.058   Rho guanine nucleotide exchange factor (GEF) 11 isofo...
ARHGEF12              0.057   Rho guanine nucleotide exchange factor (GEF) 12 [Homo...
ARHGEF18              0.055   Rho/Rac guanine nucleotide exchange factor 18 isofo...
ARHGEF18              0.055   Rho/Rac guanine nucleotide exchange factor 18 isofor...
PREX2                 0.053   DEP domain containing 2 isoform b 
PREX2                 0.053   DEP domain containing 2 isoform a 
PREX1                 0.052   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
ARHGEF1               0.052   Rho guanine nucleotide exchange factor 1 isoform 1 [...
ARHGEF1               0.052   Rho guanine nucleotide exchange factor 1 isoform 3 [...
ARHGEF1               0.052   Rho guanine nucleotide exchange factor 1 isoform 2 [...
AKAP13                0.052   A-kinase anchor protein 13 isoform 1 
AKAP13                0.052   A-kinase anchor protein 13 isoform 3 
AKAP13                0.052   A-kinase anchor protein 13 isoform 2 
ARHGEF9               0.051   Cdc42 guanine exchange factor 9 
RGNEF                 0.047   Rho-guanine nucleotide exchange factor 
ECT2                  0.046   epithelial cell transforming sequence 2 oncogene pro...
VAV3                  0.045   vav 3 guanine nucleotide exchange factor isoform 1 ...
FGD2                  0.045   FYVE, RhoGEF and PH domain containing 2 
ARHGEF4               0.043   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.043   Rho guanine nucleotide exchange factor 4 isoform b [...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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