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Search of human proteins with 32479525
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32479525 potassium voltage-gated channel, KQT-like
subfamily, member 1 isoform 2 [Homo sapiens]
(549 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,... 1098 0.0
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,... 1094 0.0
gi|236461719 potassium voltage-gated channel, KQT-like subfamily... 386 e-107
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,... 385 e-107
gi|236461942 potassium voltage-gated channel, KQT-like subfamily... 382 e-106
gi|236462079 potassium voltage-gated channel, KQT-like subfamily... 380 e-105
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i... 379 e-105
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i... 379 e-105
gi|26051262 potassium voltage-gated channel KQT-like protein 2 i... 375 e-104
gi|26051266 potassium voltage-gated channel KQT-like protein 2 i... 370 e-102
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i... 363 e-100
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H... 342 7e-94
gi|236462242 potassium voltage-gated channel, KQT-like subfamily... 323 3e-88
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i... 320 3e-87
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i... 320 3e-87
gi|88758565 potassium voltage-gated channel, shaker-related subf... 95 1e-19
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 93 5e-19
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 92 9e-19
gi|88758576 Shaw-related voltage-gated potassium channel protein... 92 1e-18
gi|24497462 Shaw-related voltage-gated potassium channel protein... 92 1e-18
gi|119395748 potassium voltage-gated channel subfamily A member ... 92 2e-18
gi|4504821 potassium voltage-gated channel, shaker-related subfa... 90 5e-18
gi|25952087 potassium voltage-gated channel, shaker-related subf... 89 8e-18
gi|25952092 potassium voltage-gated channel, shaker-related subf... 89 1e-17
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 87 3e-17
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 87 3e-17
gi|21217561 Shaw-related voltage-gated potassium channel protein... 87 3e-17
gi|21217563 Shaw-related voltage-gated potassium channel protein... 87 3e-17
gi|24497458 Shaw-related voltage-gated potassium channel protein... 87 3e-17
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 87 4e-17
>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
member 1 isoform 2 [Homo sapiens]
Length = 549
Score = 1098 bits (2841), Expect = 0.0
Identities = 549/549 (100%), Positives = 549/549 (100%)
Query: 1 MDFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGL 60
MDFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGL
Sbjct: 1 MDFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGL 60
Query: 61 WGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGT 120
WGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGT
Sbjct: 61 WGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGT 120
Query: 121 WRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGV 180
WRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGV
Sbjct: 121 WRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGV 180
Query: 181 VTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQ 240
VTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQ
Sbjct: 181 VTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQ 240
Query: 241 IPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDK 300
IPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDK
Sbjct: 241 IPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDK 300
Query: 301 DNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAE 360
DNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAE
Sbjct: 301 DNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAE 360
Query: 361 DLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQ 420
DLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQ
Sbjct: 361 DLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQ 420
Query: 421 GHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLA 480
GHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLA
Sbjct: 421 GHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLA 480
Query: 481 LITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTV 540
LITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTV
Sbjct: 481 LITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTV 540
Query: 541 PRRGPDEGS 549
PRRGPDEGS
Sbjct: 541 PRRGPDEGS 549
>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
member 1 isoform 1 [Homo sapiens]
Length = 676
Score = 1094 bits (2830), Expect = 0.0
Identities = 547/547 (100%), Positives = 547/547 (100%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG
Sbjct: 130 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 189
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR
Sbjct: 190 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 249
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT
Sbjct: 250 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 309
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP
Sbjct: 310 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 369
Query: 243 AAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDN 302
AAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDN
Sbjct: 370 AAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDN 429
Query: 303 GVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDL 362
GVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDL
Sbjct: 430 GVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDL 489
Query: 363 DLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGH 422
DLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGH
Sbjct: 490 DLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGH 549
Query: 423 LNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALI 482
LNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALI
Sbjct: 550 LNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALI 609
Query: 483 TDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPR 542
TDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPR
Sbjct: 610 TDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPR 669
Query: 543 RGPDEGS 549
RGPDEGS
Sbjct: 670 RGPDEGS 676
>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 2 [Homo sapiens]
Length = 923
Score = 386 bits (992), Expect = e-107
Identities = 219/502 (43%), Positives = 317/502 (63%), Gaps = 27/502 (5%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CLI SV STI ++ LA+ L +E V++V FG E+++R+WSAGC +Y G G
Sbjct: 134 FLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQG 193
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RLRFARKP +ID IV++AS+ V+ ++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 194 RLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWK 253
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +ELIT YIGFL LIFSS+ VYL EKDA EF +YADALWWG +T
Sbjct: 254 LLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTIT 308
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK P TW+G+ +++ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 309 LTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368
Query: 243 AAASLIQTAWRCYAAENPDSS--TWKIYIRKAPRSHTLLSPSPKP--KKSVVVKKKKFKL 298
AA+LIQ WR YAA+ S TWK +++ HT + K K+ V + + +
Sbjct: 369 PAANLIQCVWRSYAADEKSVSIATWKPHLKAL---HTCSPTNQKLSFKERVRMASPRGQS 425
Query: 299 DKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL-LEVSMPH-FMRTN 356
K + G++ IT + + +S ++ R P+L L+ S P + +
Sbjct: 426 IKSRQASVGDRRSPSTDITAEGSPTKVQKSWS---FNDRTRFRPSLRLKSSQPKPVIDAD 482
Query: 357 SFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIE 416
+ D+ E + L + I+ IR M++ VAK+KF++ +PYDV+DVIE
Sbjct: 483 TALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIE 542
Query: 417 QYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDR--------GSNTIGARLNRV 468
QYS GHL+++ RIK LQ R+DQ +GK I+ +KS+++ ++ R+ +V
Sbjct: 543 QYSAGHLDMLCRIKSLQTRVDQILGKGQ--ITSDKKSREKITAEHETTDDLSMLGRVVKV 600
Query: 469 EDKVTQLDQRLALITDMLHQLL 490
E +V ++ +L + D+ Q+L
Sbjct: 601 EKQVQSIESKLDCLLDIYQQVL 622
>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 1 [Homo sapiens]
Length = 932
Score = 385 bits (988), Expect = e-107
Identities = 218/508 (42%), Positives = 316/508 (62%), Gaps = 30/508 (5%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CLI SV STI ++ LA+ L +E V++V FG E+++R+WSAGC +Y G G
Sbjct: 134 FLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQG 193
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RLRFARKP +ID IV++AS+ V+ ++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 194 RLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWK 253
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +ELIT YIGFL LIFSS+ VYL EKDA EF +YADALWWG +T
Sbjct: 254 LLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTIT 308
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK P TW+G+ +++ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 309 LTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368
Query: 243 AAASLIQTAWRCYAAENPDSS--TWKIYIR--------KAPRSHTLLSPSPKPKKSVVVK 292
AA+LIQ WR YAA+ S TWK +++ K + S K+ V +
Sbjct: 369 PAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSQKLSFKERVRMA 428
Query: 293 KKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL-LEVSMPH 351
+ + K + G++ IT + + +S ++ R P+L L+ S P
Sbjct: 429 SPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWS---FNDRTRFRPSLRLKSSQPK 485
Query: 352 -FMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYD 410
+ ++ D+ E + L + I+ IR M++ VAK+KF++ +PYD
Sbjct: 486 PVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYD 545
Query: 411 VRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDR--------GSNTIG 462
V+DVIEQYS GHL+++ RIK LQ R+DQ +GK I+ +KS+++ ++
Sbjct: 546 VKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQ--ITSDKKSREKITAEHETTDDLSML 603
Query: 463 ARLNRVEDKVTQLDQRLALITDMLHQLL 490
R+ +VE +V ++ +L + D+ Q+L
Sbjct: 604 GRVVKVEKQVQSIESKLDCLLDIYQQVL 631
>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 3 [Homo sapiens]
Length = 942
Score = 382 bits (982), Expect = e-106
Identities = 221/518 (42%), Positives = 319/518 (61%), Gaps = 40/518 (7%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CLI SV STI ++ LA+ L +E V++V FG E+++R+WSAGC +Y G G
Sbjct: 134 FLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQG 193
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RLRFARKP +ID IV++AS+ V+ ++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 194 RLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWK 253
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +ELIT YIGFL LIFSS+ VYL EKDA EF +YADALWWG +T
Sbjct: 254 LLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTIT 308
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK P TW+G+ +++ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 309 LTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368
Query: 243 AAASLIQTAWRCYAAENPDSS--TWKIYIR----------------KAPRSHTLLSPSPK 284
AA+LIQ WR YAA+ S TWK +++ K R +T S K
Sbjct: 369 PAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKLFRMYTSRKQSQK 428
Query: 285 P--KKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSP 342
K+ V + + + K + G++ IT + + +S ++ R P
Sbjct: 429 LSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWS---FNDRTRFRP 485
Query: 343 TL-LEVSMPH-FMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKK 400
+L L+ S P + ++ D+ E + L + I+ IR M++ VAK+
Sbjct: 486 SLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKR 545
Query: 401 KFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDR---- 456
KF++ +PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +GK I+ +KS+++
Sbjct: 546 KFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQ--ITSDKKSREKITAE 603
Query: 457 ----GSNTIGARLNRVEDKVTQLDQRLALITDMLHQLL 490
++ R+ +VE +V ++ +L + D+ Q+L
Sbjct: 604 HETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVL 641
>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 4 [Homo sapiens]
Length = 951
Score = 380 bits (975), Expect = e-105
Identities = 222/531 (41%), Positives = 310/531 (58%), Gaps = 57/531 (10%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CLI SV STI ++ LA+ L +E V++V FG E+++R+WSAGC +Y G G
Sbjct: 134 FLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQG 193
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RLRFARKP +ID IV++AS+ V+ ++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 194 RLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWK 253
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +ELIT YIGFL LIFSS+ VYL EKDA EF +YADALWWG +T
Sbjct: 254 LLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTIT 308
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK P TW+G+ +++ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 309 LTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368
Query: 243 AAASLIQTAWRCYAAENPDSS--TWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDK 300
AA+LIQ WR YAA+ S TWK P L + SP K+ KF +K
Sbjct: 369 PAANLIQCVWRSYAADEKSVSIATWK------PHLKALHTCSPTKKEQGEASSSKFCSNK 422
Query: 301 D------NGVTPGEKMLTVPHITCDPPEERRLDHFSVD-------GYDSSVRKSPTLLEV 347
+K+ + P + + D + SPT ++
Sbjct: 423 QKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQK 482
Query: 348 SMPHFMRTNSFAEDLDLEGETLLTPI--------------------THISQLREHHRATI 387
S RT F L L+ I + L + I
Sbjct: 483 SWSFNDRTR-FRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVI 541
Query: 388 KVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFI 447
+ IR M++ VAK+KF++ +PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +GK I
Sbjct: 542 RAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQ--I 599
Query: 448 SVSEKSKDR--------GSNTIGARLNRVEDKVTQLDQRLALITDMLHQLL 490
+ +KS+++ ++ R+ +VE +V ++ +L + D+ Q+L
Sbjct: 600 TSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVL 650
>gi|26051260 potassium voltage-gated channel KQT-like protein 2
isoform c [Homo sapiens]
Length = 844
Score = 379 bits (974), Expect = e-105
Identities = 219/533 (41%), Positives = 326/533 (61%), Gaps = 53/533 (9%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CL+ SV STI++Y + G L+ +EIV +V FG EY VR+W+AGC +Y G G
Sbjct: 100 FLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RL+FARKP +ID++V++AS+ VL GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 160 RLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWK 219
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +EL+T YIGFL LI +S+ VYLAEK + F +YADALWWG++T
Sbjct: 220 LLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFDTYADALWWGLIT 274
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK PQTW G+ +A+ F++ +SFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 275 LTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRN 334
Query: 243 AAASLIQTAWRCYA---AENPDSSTWKIYIRKAP-RSHTLLSPSPKPKKSVVVKKKK--- 295
AA LIQ+AWR YA + STW+ Y R + L+ P + + +K K
Sbjct: 335 PAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLA 394
Query: 296 FKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL---LEVSMPHF 352
F+ D +P +K+ + P S +VR+SP+ LE S
Sbjct: 395 FRKDPPPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQA--QTVRRSPSADQSLEDSPSKV 452
Query: 353 MRTNSF--------------------AEDLDLEGETLL----TPITHISQ-LREHHRATI 387
++ SF +E+ L GE ++ P +++ L + +I
Sbjct: 453 PKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI 512
Query: 388 KVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFI 447
+ + M++ V+K+KF+++ +PYDV DVIEQYS GHL+++ RIK LQ R+DQ +G+
Sbjct: 513 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGP--- 569
Query: 448 SVSEKSKDRG--------SNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSL 492
++++K + +G ++ RL +VE +V ++++L + ++ Q + +
Sbjct: 570 AITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGI 622
>gi|26638655 potassium voltage-gated channel KQT-like protein 4
isoform b [Homo sapiens]
Length = 641
Score = 379 bits (973), Expect = e-105
Identities = 217/505 (42%), Positives = 308/505 (60%), Gaps = 53/505 (10%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CL+ SVLSTI+++ LA L +E V++V FG EY+VR+WSAGC +Y G G
Sbjct: 106 FLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQG 165
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
R RFARKP +ID IV VAS+ V+ G++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 166 RFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWK 225
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +ELIT YIGFL LIF+S+ VYLAEKDA +F SYAD+LWWG +T
Sbjct: 226 LLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDA-----NSDFSSYADSLWWGTIT 280
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK P TW+G+ +A+ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 281 LTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRM 340
Query: 243 AAASLIQTAWRCYAAENPD---SSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLD 299
AA+LIQ AWR Y+ + ++TW Y + PS + + + +
Sbjct: 341 PAANLIQAAWRLYSTDMSRAYLTATWYYY--------DSILPSFSSRMGIKDRIRMGSSQ 392
Query: 300 KDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFA 359
+ G P ++ L P + P E+ SPT ++ S RT F
Sbjct: 393 RRTG--PSKQHLAPPTMPTSPSSEQ-----------VGEATSPTKVQKSWSFNDRTR-FR 438
Query: 360 EDLDLEGETLL--TPITHISQLREHH------------RATIKVIRRMQYFVAKKKFQQA 405
L L+ T P +++ + + + I+ IR +++ VAK+KF++
Sbjct: 439 ASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKET 498
Query: 406 RKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSN------ 459
+PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +G+ EK D+G +
Sbjct: 499 LRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG-DKGPSDAEVVD 557
Query: 460 --TIGARLNRVEDKVTQLDQRLALI 482
++ R+ +VE +V ++ +L L+
Sbjct: 558 EISMMGRVVKVEKQVQSIEHKLDLL 582
>gi|26051262 potassium voltage-gated channel KQT-like protein 2
isoform b [Homo sapiens]
Length = 854
Score = 375 bits (963), Expect = e-104
Identities = 219/543 (40%), Positives = 327/543 (60%), Gaps = 63/543 (11%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CL+ SV STI++Y + G L+ +EIV +V FG EY VR+W+AGC +Y G G
Sbjct: 100 FLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RL+FARKP +ID++V++AS+ VL GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 160 RLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWK 219
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +EL+T YIGFL LI +S+ VYLAEK + F +YADALWWG++T
Sbjct: 220 LLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFDTYADALWWGLIT 274
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK PQTW G+ +A+ F++ +SFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 275 LTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRN 334
Query: 243 AAASLIQTAWRCYA---AENPDSSTWKIYIR-----------KAPRSHTLLSPSPKPKKS 288
AA LIQ+AWR YA + STW+ Y R + + L+ P + +
Sbjct: 335 PAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELL 394
Query: 289 VVVKKKK---FKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL- 344
+K K F+ D +P +K+ + P S +VR+SP+
Sbjct: 395 RNLKSKSGLAFRKDPPPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQA--QTVRRSPSAD 452
Query: 345 --LEVSMPHFMRTNSF--------------------AEDLDLEGETLL----TPITHISQ 378
LE S ++ SF +E+ L GE ++ P +++
Sbjct: 453 QSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTE 512
Query: 379 -LREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLD 437
L + +I+ + M++ V+K+KF+++ +PYDV DVIEQYS GHL+++ RIK LQ R+D
Sbjct: 513 DLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVD 572
Query: 438 QSIGKPSLFISVSEKSKDRG--------SNTIGARLNRVEDKVTQLDQRLALITDMLHQL 489
Q +G+ ++++K + +G ++ RL +VE +V ++++L + ++ Q
Sbjct: 573 QIVGRGP---AITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQR 629
Query: 490 LSL 492
+ +
Sbjct: 630 MGI 632
>gi|26051266 potassium voltage-gated channel KQT-like protein 2
isoform d [Homo sapiens]
Length = 841
Score = 370 bits (950), Expect = e-102
Identities = 212/528 (40%), Positives = 315/528 (59%), Gaps = 46/528 (8%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CL+ SV STI++Y + G L+ +EIV +V FG EY VR+W+AGC +Y G G
Sbjct: 100 FLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RL+FARKP +ID++V++AS+ VL GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 160 RLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWK 219
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +EL+T YIGFL LI +S+ VYLAEK + F +YADALWWG++T
Sbjct: 220 LLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFDTYADALWWGLIT 274
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK PQTW G+ +A+ F++ +SFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 275 LTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRN 334
Query: 243 AAASLIQTAWRCYA---AENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLD 299
AA LIQ+AWR YA + STW+ Y R ++ + +L
Sbjct: 335 PAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELL 394
Query: 300 KDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL---LEVSMPHFMRTN 356
++ G P P +VR+SP+ LE S ++
Sbjct: 395 RNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSW 454
Query: 357 SFAE-------------------DLDLEGETLL----TPITHISQ-LREHHRATIKVIRR 392
SF + + L GE ++ P +++ L + +I+ +
Sbjct: 455 SFGDRSRARQAFRIKGAASRQNSEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCV 514
Query: 393 MQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEK 452
M++ V+K+KF+++ +PYDV DVIEQYS GHL+++ RIK LQ R+DQ +G+ ++++K
Sbjct: 515 MRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGP---AITDK 571
Query: 453 SKDRG--------SNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSL 492
+ +G ++ RL +VE +V ++++L + ++ Q + +
Sbjct: 572 DRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGI 619
>gi|26638653 potassium voltage-gated channel KQT-like protein 4
isoform a [Homo sapiens]
Length = 695
Score = 363 bits (932), Expect = e-100
Identities = 223/549 (40%), Positives = 311/549 (56%), Gaps = 87/549 (15%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CL+ SVLSTI+++ LA L +E V++V FG EY+VR+WSAGC +Y G G
Sbjct: 106 FLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQG 165
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
R RFARKP +ID IV VAS+ V+ G++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 166 RFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWK 225
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +ELIT YIGFL LIF+S+ VYLAEKDA +F SYAD+LWWG +T
Sbjct: 226 LLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDA-----NSDFSSYADSLWWGTIT 280
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK P TW+G+ +A+ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 281 LTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRM 340
Query: 243 AAASLIQTAWRCYAAENPD---SSTWKIY-----------------------------IR 270
AA+LIQ AWR Y+ + ++TW Y +R
Sbjct: 341 PAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVR 400
Query: 271 KAP-------------RSHTLLSPS--PKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPH 315
+AP H S S P + +K + P ++ L P
Sbjct: 401 RAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPT 460
Query: 316 ITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLL--TPI 373
+ P E+ SPT ++ S RT F L L+ T P
Sbjct: 461 MPTSPSSEQ-----------VGEATSPTKVQKSWSFNDRTR-FRASLRLKPRTSAEDAPS 508
Query: 374 THISQLREHH---------RATIKVIRRMQ---YFVAKKKFQQARKPYDVRDVIEQYSQG 421
+++ + + A VIR ++ + VAK+KF++ +PYDV+DVIEQYS G
Sbjct: 509 EEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAG 568
Query: 422 HLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSN--------TIGARLNRVEDKVT 473
HL+++ RIK LQ R+DQ +G+ EK D+G + ++ R+ +VE +V
Sbjct: 569 HLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG-DKGPSDAEVVDEISMMGRVVKVEKQVQ 627
Query: 474 QLDQRLALI 482
++ +L L+
Sbjct: 628 SIEHKLDLL 636
>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
sapiens]
Length = 872
Score = 342 bits (876), Expect = 7e-94
Identities = 200/480 (41%), Positives = 279/480 (58%), Gaps = 44/480 (9%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FLIVL CLI +VL+T ++Y ++ L +E + FG E+ +R+W+AGC +Y G G
Sbjct: 130 FLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRG 189
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RL+FARKP+ ++D+ V++AS+ V+ VG++G V ATS +R +RFLQILRML +DR+GGTW+
Sbjct: 190 RLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWK 248
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKD-----AVNESGRVEFGSYADALW 177
LLGS + H +ELIT YIGFL LI SS+ VYL EKD A E + EF +YADALW
Sbjct: 249 LLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALW 308
Query: 178 WGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHF 237
WG++T+ TIGYGDK P+TW G+ IA+ FS+ +SFFALPAGILGSG ALKVQ++ RQKHF
Sbjct: 309 WGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHF 368
Query: 238 NRQIPAAASLIQTAWRCYAAENPDS----STWKIYIRKAPRSHTLLSPSPKPKKSVVVKK 293
++ AA LIQ AWR YA NP+ +TW+ Y +
Sbjct: 369 EKRRKPAAELIQAAWRYYAT-NPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLL 427
Query: 294 KKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFM 353
+ +L G K+ T +VD + S K P + ++
Sbjct: 428 DRVRLSNPRGSNTKGKLFT---------------PLNVDAIEESPSKEPKPVGLNNKERF 472
Query: 354 RT----NSFAEDLDLEGETLLTPITH---------ISQLREHHRATIKVIRRMQYFVAKK 400
RT ++A E P+ I + +A I+ +R +Q+ + KK
Sbjct: 473 RTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKK 532
Query: 401 KFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQ--SIGKPSLFISVSEKSKDRGS 458
KF++ +PYDV+DVIEQYS GHL+++ RIK LQ R+D + G PS + K +GS
Sbjct: 533 KFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPS---TPKHKKSQKGS 589
>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 5 [Homo sapiens]
Length = 822
Score = 323 bits (828), Expect = 3e-88
Identities = 164/300 (54%), Positives = 216/300 (72%), Gaps = 11/300 (3%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CLI SV STI ++ LA+ L +E V++V FG E+++R+WSAGC +Y G G
Sbjct: 134 FLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQG 193
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RLRFARKP +ID IV++AS+ V+ ++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 194 RLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWK 253
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +ELIT YIGFL LIFSS+ VYL EKDA EF +YADALWWG +T
Sbjct: 254 LLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTIT 308
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK P TW+G+ +++ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 309 LTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368
Query: 243 AAASLIQTAWRCYAAENPDSS--TWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDK 300
AA+LIQ WR YAA+ S TWK +++ HT SP+ K + + KF + K
Sbjct: 369 PAANLIQCVWRSYAADEKSVSIATWKPHLKAL---HT-CSPTKKEQGEASSRIMKFHVAK 424
Score = 78.2 bits (191), Expect = 2e-14
Identities = 42/108 (38%), Positives = 70/108 (64%), Gaps = 10/108 (9%)
Query: 391 RRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVS 450
R M++ VAK+KF++ +PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +GK I+
Sbjct: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQ--ITSD 473
Query: 451 EKSKDR--------GSNTIGARLNRVEDKVTQLDQRLALITDMLHQLL 490
+KS+++ ++ R+ +VE +V ++ +L + D+ Q+L
Sbjct: 474 KKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVL 521
>gi|26051268 potassium voltage-gated channel KQT-like protein 2
isoform e [Homo sapiens]
Length = 393
Score = 320 bits (819), Expect = 3e-87
Identities = 156/271 (57%), Positives = 204/271 (75%), Gaps = 8/271 (2%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CL+ SV STI++Y + G L+ +EIV +V FG EY VR+W+AGC +Y G G
Sbjct: 100 FLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RL+FARKP +ID++V++AS+ VL GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 160 RLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWK 219
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +EL+T YIGFL LI +S+ VYLAEK + F +YADALWWG++T
Sbjct: 220 LLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFDTYADALWWGLIT 274
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK PQTW G+ +A+ F++ +SFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 275 LTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRN 334
Query: 243 AAASLIQTAWRCYA---AENPDSSTWKIYIR 270
AA LIQ+AWR YA + STW+ Y R
Sbjct: 335 PAAGLIQSAWRFYATNLSRTDLHSTWQYYER 365
>gi|26051264 potassium voltage-gated channel KQT-like protein 2
isoform a [Homo sapiens]
Length = 872
Score = 320 bits (819), Expect = 3e-87
Identities = 156/271 (57%), Positives = 204/271 (75%), Gaps = 8/271 (2%)
Query: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
FL+V CL+ SV STI++Y + G L+ +EIV +V FG EY VR+W+AGC +Y G G
Sbjct: 100 FLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
Query: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
RL+FARKP +ID++V++AS+ VL GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 160 RLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWK 219
Query: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
LLGSVV+ H +EL+T YIGFL LI +S+ VYLAEK + F +YADALWWG++T
Sbjct: 220 LLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFDTYADALWWGLIT 274
Query: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
+TTIGYGDK PQTW G+ +A+ F++ +SFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 275 LTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRN 334
Query: 243 AAASLIQTAWRCYA---AENPDSSTWKIYIR 270
AA LIQ+AWR YA + STW+ Y R
Sbjct: 335 PAAGLIQSAWRFYATNLSRTDLHSTWQYYER 365
Score = 78.6 bits (192), Expect = 1e-14
Identities = 44/147 (29%), Positives = 88/147 (59%), Gaps = 16/147 (10%)
Query: 359 AEDLDLEGETLLT----PITHISQ-LREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRD 413
+E+ L GE ++ P +++ L + +I+ + M++ V+K+KF+++ +PYDV D
Sbjct: 507 SEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMD 566
Query: 414 VIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRG--------SNTIGARL 465
VIEQYS GHL+++ RIK LQ R+DQ +G+ ++++K + +G ++ RL
Sbjct: 567 VIEQYSAGHLDMLSRIKSLQSRVDQIVGRGP---AITDKDRTKGPAEAELPEDPSMMGRL 623
Query: 466 NRVEDKVTQLDQRLALITDMLHQLLSL 492
+VE +V ++++L + ++ Q + +
Sbjct: 624 GKVEKQVLSMEKKLDFLVNIYMQRMGI 650
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 95.1 bits (235), Expect = 1e-19
Identities = 59/201 (29%), Positives = 101/201 (50%), Gaps = 19/201 (9%)
Query: 30 FWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCV- 88
F +E + +++F E +VR ++ C SK F+R +++ID++ ++ + L
Sbjct: 296 FVVETLCIIWFSFELLVRFFA--CPSKAT-------FSRNIMNLIDIVAIIPYFITLGTE 346
Query: 89 -----GSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGF 143
G+ Q + + +R IR +++ R+ + R ++LG + +EL ++ F
Sbjct: 347 LAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 406
Query: 144 LGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIAS 203
+G+I S VY AE D F S DA WW VVT+TT+GYGD P T GK + S
Sbjct: 407 IGVILFSSAVYFAEADDPTSG----FSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGS 462
Query: 204 CFSVFAISFFALPAGILGSGF 224
++ + ALP ++ S F
Sbjct: 463 LCAIAGVLTIALPVPVIVSNF 483
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 93.2 bits (230), Expect = 5e-19
Identities = 65/214 (30%), Positives = 107/214 (50%), Gaps = 22/214 (10%)
Query: 20 QYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVV 79
Q + T F +E + +++F E++VR ++ C SK F ++IID++ +
Sbjct: 213 QQSTSFTDPFFIVETLCIIWFSFEFLVRFFA--CPSK-------AGFFTNIMNIIDIVAI 263
Query: 80 VASMVVLCV--------GSKGQVFATSAI-RGIRFLQILRMLHVDRQGGTWRLLGSVVFI 130
+ + L +GQ + AI R IR +++ R+ + R ++LG +
Sbjct: 264 IPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKA 323
Query: 131 HRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGD 190
+EL ++ F+G+I S VY AE D ES +F S DA WW VV++TT+GYGD
Sbjct: 324 SMRELGLLIFFLFIGVILFSSAVYFAEADE-RES---QFPSIPDAFWWAVVSMTTVGYGD 379
Query: 191 KVPQTWVGKTIASCFSVFAISFFALPAGILGSGF 224
VP T GK + S ++ + ALP ++ S F
Sbjct: 380 MVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNF 413
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 92.4 bits (228), Expect = 9e-19
Identities = 61/205 (29%), Positives = 102/205 (49%), Gaps = 23/205 (11%)
Query: 30 FWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCV- 88
F +E V +V+F E+VVR ++ C S+ + F + ++IID++ ++ + L
Sbjct: 372 FIVETVCIVWFSFEFVVRCFA--CPSQAL-------FFKNIMNIIDIVSILPYFITLGTD 422
Query: 89 ---------GSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTL 139
G + Q + + +R IR +++ R+ + R ++LG + +EL +
Sbjct: 423 LAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLI 482
Query: 140 YIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGK 199
+ F+G+I S VY AE D F S DA WW VVT+TT+GYGD P T GK
Sbjct: 483 FFLFIGVILFSSAVYFAEADEPT----THFQSIPDAFWWAVVTMTTVGYGDMKPITVGGK 538
Query: 200 TIASCFSVFAISFFALPAGILGSGF 224
+ S ++ + ALP ++ S F
Sbjct: 539 IVGSLCAIAGVLTIALPVPVIVSNF 563
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 92.0 bits (227), Expect = 1e-18
Identities = 76/314 (24%), Positives = 143/314 (45%), Gaps = 39/314 (12%)
Query: 29 LFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCV 88
L ++E V V++F E++VR+ V L F + ++IID + ++ + + +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI---------VCCPDTLDFVKNLLNIIDFVAILPFYLEVGL 331
Query: 89 G---SKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLG 145
SK +R +RF++ILR+ + R R+LG + E + + LG
Sbjct: 332 SGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 391
Query: 146 LIFSSYFVYLAEKDAVNESG-----RVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKT 200
++ + +Y AE+ S +F + WW VVT+TT+GYGD P+TW G
Sbjct: 392 VLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGML 451
Query: 201 IASCFSVFAISFFALPAGIL----GSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYA 256
+ + ++ + A+P ++ G ++L + +++ K + +P A L ++ C +
Sbjct: 452 VGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQL-ESPMYCKS 510
Query: 257 AENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKD---NGVTPGEK--ML 311
E +PR T SP ++ ++++K+ ++ N V E+ L
Sbjct: 511 EET------------SPRDSTCSDTSPPAREEGMIERKRADSKQNGDANAVLSDEEGAGL 558
Query: 312 TVPHITCDPPEERR 325
T P + PEERR
Sbjct: 559 TQPLASSPTPEERR 572
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 92.0 bits (227), Expect = 1e-18
Identities = 76/314 (24%), Positives = 143/314 (45%), Gaps = 39/314 (12%)
Query: 29 LFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCV 88
L ++E V V++F E++VR+ V L F + ++IID + ++ + + +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI---------VCCPDTLDFVKNLLNIIDFVAILPFYLEVGL 331
Query: 89 G---SKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLG 145
SK +R +RF++ILR+ + R R+LG + E + + LG
Sbjct: 332 SGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 391
Query: 146 LIFSSYFVYLAEKDAVNESG-----RVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKT 200
++ + +Y AE+ S +F + WW VVT+TT+GYGD P+TW G
Sbjct: 392 VLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGML 451
Query: 201 IASCFSVFAISFFALPAGIL----GSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYA 256
+ + ++ + A+P ++ G ++L + +++ K + +P A L ++ C +
Sbjct: 452 VGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQL-ESPMYCKS 510
Query: 257 AENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKD---NGVTPGEK--ML 311
E +PR T SP ++ ++++K+ ++ N V E+ L
Sbjct: 511 EET------------SPRDSTCSDTSPPAREEGMIERKRADSKQNGDANAVLSDEEGAGL 558
Query: 312 TVPHITCDPPEERR 325
T P + PEERR
Sbjct: 559 TQPLASSPTPEERR 572
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 91.7 bits (226), Expect = 2e-18
Identities = 62/217 (28%), Positives = 105/217 (48%), Gaps = 21/217 (9%)
Query: 16 STIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIID 75
+T+ + + T F +E + +++F E VVR ++ C SK F + ++ ID
Sbjct: 208 TTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFA--CPSK-------TDFFKNIMNFID 258
Query: 76 LIVVVASMVVLCV-------GSKGQVFATSAI-RGIRFLQILRMLHVDRQGGTWRLLGSV 127
++ ++ + L KG+ + AI R IR +++ R+ + R ++LG
Sbjct: 259 IVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQT 318
Query: 128 VFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIG 187
+ +EL ++ F+G+I S VY AE E F S DA WW VV++TT+G
Sbjct: 319 LKASMRELGLLIFFLFIGVILFSSAVYFAEA----EEAESHFSSIPDAFWWAVVSMTTVG 374
Query: 188 YGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGF 224
YGD P T GK + S ++ + ALP ++ S F
Sbjct: 375 YGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNF 411
>gi|4504821 potassium voltage-gated channel, shaker-related
subfamily, member 6 [Homo sapiens]
Length = 529
Score = 90.1 bits (222), Expect = 5e-18
Identities = 70/228 (30%), Positives = 106/228 (46%), Gaps = 31/228 (13%)
Query: 13 SVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPIS 72
S LST+ + T F +E + +V+F E +VR + C SK F R ++
Sbjct: 249 SSLSTLG--GSFFTDPFFLVETLCIVWFTFELLVRF--SACPSKPA-------FFRNIMN 297
Query: 73 IIDLIVVVASMVVLCV---------------GSKGQVFATSAI-RGIRFLQILRMLHVDR 116
IIDL+ + + L G GQ + AI R IR +++ R+ + R
Sbjct: 298 IIDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSR 357
Query: 117 QGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADAL 176
++LG + +EL ++ F+G+I S VY AE D + F S DA
Sbjct: 358 HSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSL----FPSIPDAF 413
Query: 177 WWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGF 224
WW VVT+TT+GYGD P T GK + S ++ + ALP ++ S F
Sbjct: 414 WWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNF 461
>gi|25952087 potassium voltage-gated channel, shaker-related
subfamily, member 5 [Homo sapiens]
Length = 613
Score = 89.4 bits (220), Expect = 8e-18
Identities = 64/208 (30%), Positives = 100/208 (48%), Gaps = 26/208 (12%)
Query: 30 FWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCV- 88
F +E V++F E +VR ++ C SK F+R ++IID++ + + L
Sbjct: 325 FIVETTCVIWFTFELLVRFFA--CPSK-------AGFSRNIMNIIDVVAIFPYFITLGTE 375
Query: 89 -----------GSKGQVFATSAI-RGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELI 136
G GQ + AI R IR +++ R+ + R ++LG + +EL
Sbjct: 376 LAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELG 435
Query: 137 TTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTW 196
++ F+G+I S VY AE D + F S DA WW VVT+TT+GYGD P T
Sbjct: 436 LLIFFLFIGVILFSSAVYFAEAD----NQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITV 491
Query: 197 VGKTIASCFSVFAISFFALPAGILGSGF 224
GK + S ++ + ALP ++ S F
Sbjct: 492 GGKIVGSLCAIAGVLTIALPVPVIVSNF 519
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 89.0 bits (219), Expect = 1e-17
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 19/202 (9%)
Query: 30 FWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCV- 88
F +E + + +F E +VRL C SK + F + +++ID + ++ V L
Sbjct: 210 FVVETLCICWFSFELLVRLLV--CPSKAI-------FFKNVMNLIDFVAILPYFVALGTE 260
Query: 89 -----GSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGF 143
G Q + + +R IR +++ R+ + R ++LG + +EL ++ F
Sbjct: 261 LARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLF 320
Query: 144 LGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIAS 203
+G++ S VY AE D V+ F S ++ WW VVT+TT+GYGD P T GK + S
Sbjct: 321 IGVVLFSSAVYFAEVDRVDS----HFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGS 376
Query: 204 CFSVFAISFFALPAGILGSGFA 225
++ + +LP ++ S F+
Sbjct: 377 LCAIAGVLTISLPVPVIVSNFS 398
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 87.4 bits (215), Expect = 3e-17
Identities = 60/204 (29%), Positives = 97/204 (47%), Gaps = 15/204 (7%)
Query: 30 FWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVG 89
F M+ V+ F EY++RL++A R RF R +S+ID++ ++ + L V
Sbjct: 232 FCMDTACVLIFTGEYLLRLFAAP---------SRCRFLRSVMSLIDVVAILPYYIGLLVP 282
Query: 90 SKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFS 149
V + A +R ++ R+ R R+LG + EL L+ + +I
Sbjct: 283 KNDDV--SGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIF 340
Query: 150 SYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFA 209
+ ++ AEK + + F S A W+ +VT+TT+GYGD VP T GK S S+
Sbjct: 341 ATVMFYAEKG----TNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSG 396
Query: 210 ISFFALPAGILGSGFALKVQQKQR 233
+ ALP ++ S F+ Q QR
Sbjct: 397 VLVIALPVPVIVSNFSRIYHQNQR 420
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 87.4 bits (215), Expect = 3e-17
Identities = 67/233 (28%), Positives = 107/233 (45%), Gaps = 19/233 (8%)
Query: 19 EQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIV 78
E+YA F ++ V+ F EY++RL +A R RF R +SIID++
Sbjct: 223 ERYAV----AFFCLDTACVMIFTVEYLLRLAAAP---------SRYRFVRSVMSIIDVVA 269
Query: 79 VVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITT 138
++ + L + V + A +R ++ R+ R R+LG + EL
Sbjct: 270 ILPYYIGLVMTDNEDV--SGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFL 327
Query: 139 LYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVG 198
L+ + +I + ++ AEK S +F S A W+ +VT+TT+GYGD VP+T G
Sbjct: 328 LFSLTMAIIIFATVMFYAEKG----SSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAG 383
Query: 199 KTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTA 251
K S S+ + ALP ++ S F+ Q QR Q A + I+ A
Sbjct: 384 KIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAA 436
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 87.4 bits (215), Expect = 3e-17
Identities = 61/241 (25%), Positives = 114/241 (47%), Gaps = 21/241 (8%)
Query: 16 STIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIID 75
S + QY L ++E V VV+F E++VR+ V +L F + ++IID
Sbjct: 269 SVVLQYEIETDPALTYVEGVCVVWFTFEFLVRI---------VFSPNKLEFIKNLLNIID 319
Query: 76 LIVVVASMVVLCVG---SKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHR 132
+ ++ + + + SK +R +RF++ILR+ + R R+LG +
Sbjct: 320 FVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRAST 379
Query: 133 QELITTLYIGFLGLIFSSYFVYLAEKDAV-----NESGRVEFGSYADALWWGVVTVTTIG 187
E + + LG++ + +Y AE+ + S +F + WW VVT+TT+G
Sbjct: 380 NEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLG 439
Query: 188 YGDKVPQTWVGKTIASCFSVFAISFFALPAGIL----GSGFALKVQQKQRQKHFNRQIPA 243
YGD PQTW G + + ++ + A+P ++ G ++L + +++ + + IP
Sbjct: 440 YGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPP 499
Query: 244 A 244
A
Sbjct: 500 A 500
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 87.4 bits (215), Expect = 3e-17
Identities = 61/241 (25%), Positives = 114/241 (47%), Gaps = 21/241 (8%)
Query: 16 STIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIID 75
S + QY L ++E V VV+F E++VR+ V +L F + ++IID
Sbjct: 269 SVVLQYEIETDPALTYVEGVCVVWFTFEFLVRI---------VFSPNKLEFIKNLLNIID 319
Query: 76 LIVVVASMVVLCVG---SKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHR 132
+ ++ + + + SK +R +RF++ILR+ + R R+LG +
Sbjct: 320 FVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRAST 379
Query: 133 QELITTLYIGFLGLIFSSYFVYLAEKDAV-----NESGRVEFGSYADALWWGVVTVTTIG 187
E + + LG++ + +Y AE+ + S +F + WW VVT+TT+G
Sbjct: 380 NEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLG 439
Query: 188 YGDKVPQTWVGKTIASCFSVFAISFFALPAGIL----GSGFALKVQQKQRQKHFNRQIPA 243
YGD PQTW G + + ++ + A+P ++ G ++L + +++ + + IP
Sbjct: 440 YGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPP 499
Query: 244 A 244
A
Sbjct: 500 A 500
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 87.4 bits (215), Expect = 3e-17
Identities = 61/241 (25%), Positives = 114/241 (47%), Gaps = 21/241 (8%)
Query: 16 STIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIID 75
S + QY L ++E V VV+F E++VR+ V +L F + ++IID
Sbjct: 269 SVVLQYEIETDPALTYVEGVCVVWFTFEFLVRI---------VFSPNKLEFIKNLLNIID 319
Query: 76 LIVVVASMVVLCVG---SKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHR 132
+ ++ + + + SK +R +RF++ILR+ + R R+LG +
Sbjct: 320 FVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRAST 379
Query: 133 QELITTLYIGFLGLIFSSYFVYLAEKDAV-----NESGRVEFGSYADALWWGVVTVTTIG 187
E + + LG++ + +Y AE+ + S +F + WW VVT+TT+G
Sbjct: 380 NEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLG 439
Query: 188 YGDKVPQTWVGKTIASCFSVFAISFFALPAGIL----GSGFALKVQQKQRQKHFNRQIPA 243
YGD PQTW G + + ++ + A+P ++ G ++L + +++ + + IP
Sbjct: 440 YGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPP 499
Query: 244 A 244
A
Sbjct: 500 A 500
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 87.0 bits (214), Expect = 4e-17
Identities = 63/222 (28%), Positives = 105/222 (47%), Gaps = 15/222 (6%)
Query: 30 FWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVG 89
F ++ V+ F EY++RL++A R RF R +SIID++ ++ + L +
Sbjct: 227 FCLDTACVMIFTVEYLLRLFAAP---------SRYRFIRSVMSIIDVVAIMPYYIGLVMT 277
Query: 90 SKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFS 149
+ V + A +R ++ R+ R R+LG + EL L+ + +I
Sbjct: 278 NNEDV--SGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIF 335
Query: 150 SYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFA 209
+ ++ AEK S +F S + W+ +VT+TT+GYGD VP+T GK S S+
Sbjct: 336 ATVMFYAEKG----SSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSG 391
Query: 210 ISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTA 251
+ ALP ++ S F+ Q QR Q A + I+ A
Sbjct: 392 VLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRVA 433
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,343,434
Number of Sequences: 37866
Number of extensions: 1005862
Number of successful extensions: 3522
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 3345
Number of HSP's gapped (non-prelim): 195
length of query: 549
length of database: 18,247,518
effective HSP length: 107
effective length of query: 442
effective length of database: 14,195,856
effective search space: 6274568352
effective search space used: 6274568352
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.