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Search of human proteins with 32455273
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32455273 WNK lysine deficient protein kinase 2 [Homo
sapiens]
(2217 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 4486 0.0
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 703 0.0
gi|50845418 WNK lysine deficient protein kinase 3 isoform 1 [Hom... 663 0.0
gi|50845416 WNK lysine deficient protein kinase 3 isoform 2 [Hom... 663 0.0
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 580 e-165
gi|160707881 formin 2 [Homo sapiens] 162 4e-39
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 152 3e-36
gi|7019333 nuclear receptor binding protein [Homo sapiens] 151 6e-36
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 140 1e-32
gi|163965366 nascent polypeptide-associated complex alpha subuni... 136 3e-31
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 132 5e-30
gi|47132519 Ras association and pleckstrin homology domains 1 is... 130 2e-29
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 129 3e-29
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 121 7e-27
gi|116284392 mucin 2 precursor [Homo sapiens] 121 9e-27
gi|148839316 NIMA-related kinase 4 [Homo sapiens] 120 2e-26
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 119 3e-26
gi|110349719 titin isoform N2-A [Homo sapiens] 115 4e-25
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 115 5e-25
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 112 5e-24
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 112 5e-24
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 112 5e-24
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 112 5e-24
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 111 7e-24
gi|42794767 mitogen-activated protein kinase kinase kinase 3 iso... 111 7e-24
gi|42794765 mitogen-activated protein kinase kinase kinase 3 iso... 111 7e-24
gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens] 110 1e-23
gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens] 110 1e-23
gi|4507831 Unc-51-like kinase 1 [Homo sapiens] 110 2e-23
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 108 6e-23
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 4486 bits (11635), Expect = 0.0
Identities = 2217/2217 (100%), Positives = 2217/2217 (100%)
Query: 1 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 60
MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA
Sbjct: 1 MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAA 60
Query: 61 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 120
EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG
Sbjct: 61 EAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVG 120
Query: 121 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 180
TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE
Sbjct: 121 TQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDE 180
Query: 181 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 240
DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK
Sbjct: 181 DDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFK 240
Query: 241 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 300
EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS
Sbjct: 241 EEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRS 300
Query: 301 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 360
WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT
Sbjct: 301 WCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGT 360
Query: 361 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 420
PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK
Sbjct: 361 PEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK 420
Query: 421 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 480
VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV
Sbjct: 421 VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWV 480
Query: 481 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 540
EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ
Sbjct: 481 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 540
Query: 541 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 600
WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP
Sbjct: 541 WRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP 600
Query: 601 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 660
PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP
Sbjct: 601 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 660
Query: 661 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 720
VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG
Sbjct: 661 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 720
Query: 721 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 780
PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM
Sbjct: 721 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 780
Query: 781 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL
Sbjct: 781 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
Query: 841 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 900
PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH
Sbjct: 841 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 900
Query: 901 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 960
SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP
Sbjct: 901 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP 960
Query: 961 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 1020
TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG
Sbjct: 961 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 1020
Query: 1021 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1080
SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV
Sbjct: 1021 SQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1080
Query: 1081 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1140
QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG
Sbjct: 1081 QSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGG 1140
Query: 1141 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1200
SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK
Sbjct: 1141 SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDK 1200
Query: 1201 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1260
MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM
Sbjct: 1201 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1260
Query: 1261 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1320
LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE
Sbjct: 1261 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1320
Query: 1321 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1380
HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP
Sbjct: 1321 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1380
Query: 1381 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1440
PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH
Sbjct: 1381 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1440
Query: 1441 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1500
EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL
Sbjct: 1441 EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1500
Query: 1501 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1560
PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL
Sbjct: 1501 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1560
Query: 1561 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1620
YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ
Sbjct: 1561 YQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQ 1620
Query: 1621 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1680
PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF
Sbjct: 1621 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1680
Query: 1681 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1740
VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS
Sbjct: 1681 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1740
Query: 1741 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1800
PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG
Sbjct: 1741 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVG 1800
Query: 1801 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1860
VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR
Sbjct: 1801 VGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1860
Query: 1861 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1920
VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE
Sbjct: 1861 VGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIE 1920
Query: 1921 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1980
ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS
Sbjct: 1921 ALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADS 1980
Query: 1981 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 2040
SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW
Sbjct: 1981 SRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGW 2040
Query: 2041 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2100
TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG
Sbjct: 2041 TVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG 2100
Query: 2101 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2160
PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA
Sbjct: 2101 PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEA 2160
Query: 2161 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDPESEKPD 2217
QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDPESEKPD
Sbjct: 2161 QAGWAAPGEARAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDPESEKPD 2217
>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
Length = 2382
Score = 703 bits (1814), Expect = 0.0
Identities = 470/975 (48%), Positives = 555/975 (56%), Gaps = 143/975 (14%)
Query: 40 RFLRRSVV---ESDQEEPPGLEA--------AEAPGPQPPQPLQRRVLLLCKTRRLIAER 88
RF RRSV+ + E PGL A P PP+P + + T ++
Sbjct: 78 RFFRRSVICDSNATALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQV---- 133
Query: 89 ARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
A PAA APG A AGP P T P+ R +
Sbjct: 134 -----AQQPPAA-----AAPGEQAVAGPAP---------------STVPSSTSKDRPVSQ 168
Query: 149 ATVRKEDEGAAEAKPEPGRTRRDEPEEE----EDDEDDL--KAVATSLDGRFLKFDIELG 202
++ E A+ G EP+EE +DD ++L KAV S DGRFLKFDIE+G
Sbjct: 169 PSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIG 228
Query: 203 RGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWE 262
RGSFKTVYKGLDTET VEVAWCELQDRKLTK ERQRFKEEAEMLKGLQHPNIVRFYD WE
Sbjct: 229 RGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWE 288
Query: 263 SSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHR 322
S+ KGK+CIVLVTELMTSGTLKTYLKRFKVMK KVLRSWCRQILKGL FLHTRTPPIIHR
Sbjct: 289 STVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHR 348
Query: 323 DLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAF 382
DLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEE YDESVDVYAF
Sbjct: 349 DLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAF 408
Query: 383 GMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERY 442
GMCMLEMATSEYPYSECQNAAQIYR+VT G+KPASF+KV PE+KEII CI +NK+ERY
Sbjct: 409 GMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERY 468
Query: 443 EIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWVEDPKKLKGKPKDNGAIEFTFDL 502
IKDLL+HAFF E+TGVRVELAEED G K I L L +ED KKLKGK KDN AIEF+FDL
Sbjct: 469 SIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDL 528
Query: 503 EKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRE--RIWPALQPKEQQDVGS 560
E++ P++VAQEM+ESG+ E D K +AK+I+DRV+LI+ +RE ++ Q K++Q+ S
Sbjct: 529 ERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESS 588
Query: 561 ------------------PDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPT 602
P + G P + Q EPEEPEADQH
Sbjct: 589 LKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQV------EPEEPEADQH-QQLQ 641
Query: 603 LPTSATSLASDSTFDSGQGSTVYSDSQ-SSQQSVMLGSLADAA----------PSPAQCV 651
+ S+ SD T DSGQGS+V+++S+ SSQQ+V GS + A PS Q
Sbjct: 642 YQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQ 701
Query: 652 CSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGS---VPAPACPPSLQQHFPDPAMSFAP 708
P G P S+ + QP+++ V S + P +QQ P P +
Sbjct: 702 SQP---HGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAP-PQQTVQY 757
Query: 709 VLPPPSTPMPTGPGQPAPPGQQPP-----------PLAQPTPLPQVLAPQPVVPLQP--V 755
L ST QP Q P P++QP P Q PQ V QP V
Sbjct: 758 SLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQG-EPQIPVATQPSVV 816
Query: 756 PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVP------PITPLAG 809
P H + P Q PL P P P++Q+P P + PIT AG
Sbjct: 817 PVHSGAHFLPVGQ--------PLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAG 868
Query: 810 I---------DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAP--LPPASPALPL-- 856
I A+P + +TV P P P LPS P L PA ++ +
Sbjct: 869 ITQPLLTLASSATTAAIPGV--STVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPA 926
Query: 857 ---QAVKLPHPPGAPLAMPCRTIVPNAPATIPLLA-VAP-PGVAALSIHSAVAQLPGQPV 911
QA ++P G L + P P P + +AP VA++ IHS V P P
Sbjct: 927 NLGQAAEVPLSSGDVL---YQGFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLS-PPMPT 982
Query: 912 YPAAFPQMAPTDVPP 926
A P PT V P
Sbjct: 983 EVLATPGYFPTVVQP 997
Score = 213 bits (541), Expect = 2e-54
Identities = 237/907 (26%), Positives = 358/907 (39%), Gaps = 124/907 (13%)
Query: 755 VPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLP 814
VP H+P S V A +Q + P + Q +Q P + V P+
Sbjct: 690 VPGHIP------STVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQH----- 738
Query: 815 PALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCR 874
P PP Q ++ S ++ A P QA ++ A +P
Sbjct: 739 ---PQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVS 795
Query: 875 TIVPNAPATIPLLAVAPPGVAALSIHSAVAQLP-GQPVYPAAFPQMAPTDVPPSPHHTVQ 933
VP + P V + +HS LP GQP+ PQ + +P S H
Sbjct: 796 QPVPTIQGEPQIPVATQPSV--VPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHV-- 851
Query: 934 NMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQ--PMLPPQPV 991
+ Q P + P TL P V+P Q +L P
Sbjct: 852 ----STAQTGFSSLPITMAAGITQPLLTLASSATTAAIPG--VSTVVPSQLPTLLQPVTQ 905
Query: 992 LPPQPALPVRPEPLQPHLPEQAAPA---------ATPGSQILLG--------HPAPYAVD 1034
LP Q V P+ LQP + PA + G + G +P +
Sbjct: 906 LPSQ----VHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIA 961
Query: 1035 VAAQVPTVPVPPAAVLSPPLPEVLLPAA---PELLPQFPSS-----LATVSASVQ-SVPT 1085
++ V +V + + VLSPP+P +L P ++ + S + V VQ S P
Sbjct: 962 PSSNVASVCIH-STVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPG 1020
Query: 1086 QTATLLPPANPP---LPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSD 1142
+ P + L G++ P EPV Q +P L S +S SD
Sbjct: 1021 GSLAQAPTTSSQQAVLESTQGVSQVAPA-----EPVAVAQTQATQPTTLASSVDS-AHSD 1074
Query: 1143 VTSGKELSDSCEGA-FGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKM 1201
V SG +SD E GR EGR ++H+R+S R+RSR E+ SRP+L ILNV N GD++
Sbjct: 1075 VASG--MSDGNENVPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRV 1132
Query: 1202 VECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDML 1261
VECQLETHN KMVTFKFDLDGD P+EIAT MV +DFIL ERE+F++Q++++++KA++ML
Sbjct: 1133 VECQLETHNRKMVTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEML 1192
Query: 1262 SEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQN--------------VLH 1307
SED + D G +G + + + P+ + V+H
Sbjct: 1193 SEDVSVEPEGDQGLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVH 1252
Query: 1308 TGKRWFIICPVAEHPAPEA---PESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLAS 1364
+ R FI+ PV E E+ P +S + + LS ++ S L
Sbjct: 1253 SAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRR 1312
Query: 1365 QQLLSQAGPSNPPGAPPAPLAPSSPP----VTALPQDGAA----PATSTMPEPASGTASQ 1416
Q+ + P + P P PP + +P AA PATS+ P S + Q
Sbjct: 1313 AQMTEGPNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQ 1372
Query: 1417 A----------GGPGTPQGLTSELETSQPLAETHEAPLAVQ-------PLVVGLAPCTPA 1459
+ G T G+ + P+ E+P+ P VV ++ +P+
Sbjct: 1373 SEVTVPTEEGIAGVATSTGVVT--SGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPS 1430
Query: 1460 PEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPL 1519
+ ++ P+ S S + + P P PA V + ++ + +
Sbjct: 1431 LQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLT 1490
Query: 1520 GPTVPPQPPSALE------SDGEGPPPRVGFVDSTIKSLDEKLRT----LLYQEHVPTSS 1569
+ PS S P V + SLD+ + L + P+SS
Sbjct: 1491 SVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSS 1550
Query: 1570 ASAGTPV 1576
+S G V
Sbjct: 1551 SSPGAGV 1557
Score = 145 bits (367), Expect = 3e-34
Identities = 248/987 (25%), Positives = 370/987 (37%), Gaps = 223/987 (22%)
Query: 1315 ICPVAEHPAPEAPESSPPLP----LSSLPPEASQDSAPYKDQLSSKE-QPSFLASQQLLS 1369
I PV+E P + SS +P +S+ P ++ + +SS PS S S
Sbjct: 1400 IPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSAS 1459
Query: 1370 QAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSE 1429
G + PG P P V + G+ +T+ ++ T+ P T L+ +
Sbjct: 1460 AGGSTATPG-------PKPPAVVSQQAAGSTTVGATLTSVSTTTSF----PSTASQLSIQ 1508
Query: 1430 LE--TSQP-LAET-----HEAPLAVQPLVVGLAPCTPAPEAASTRDASAPR--------- 1472
L TS P LAET H GLA AP ++S+ A
Sbjct: 1509 LSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLH 1568
Query: 1473 ----------EPLPPPAPEPSPHSGTPQ----PALGQPAPLLPAAVGAVSLATSQLPSPP 1518
P+ P A P+ PQ P L QP +PA +L SQ P P
Sbjct: 1569 PLVIPSVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPVANVPAV--QQTLIHSQ-PQPA 1625
Query: 1519 LGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEV 1578
L P P ++SD + P + IK+L+EKLR+L + EH + + A +E
Sbjct: 1626 LLPNQPHTHCPEVDSDTQPKAPGI----DDIKTLEEKLRSL-FSEHSSSGAQHASVSLET 1680
Query: 1579 ----------GDRDFTLEPLRGDQPRSEVCGGDLALP------PVPKEAVSGRVQLP--- 1619
G + P + + C LP PV G+V P
Sbjct: 1681 SLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQVSTPVST 1740
Query: 1620 -----QPLVEKSELAPTRGAVMEQGTS----------------SSMTAESSPRSMLGYDR 1658
+P S+ T+ V+ GT S+T P L D
Sbjct: 1741 TTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQSQQPLEDL--DA 1798
Query: 1659 DGRQVASDSHV-----VPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGG 1713
R+ S + V V P + A +P + G S + P + T G
Sbjct: 1799 QLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQP------QKGVSQVKEGPV-LATSSG 1851
Query: 1714 QASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDV 1773
++ + + E ++ S AK+V S S + +SP S P+
Sbjct: 1852 AGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKPEPNG 1911
Query: 1774 YLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVS-------------------------SD 1808
SS DV + + TAS + G+P +D
Sbjct: 1912 ITIPGISS-DVPESAHKT-TASEAKSDTGQPTKVGRFQVTTTANKVGRFSVSKTEDKITD 1969
Query: 1809 SGDEGPRARPPVQ--KQASLPV------------SGSVAGDFVKKATAFLQRPSRAGSLG 1854
+ EGP A PP +QA LP + G AFL R GS
Sbjct: 1970 TKKEGPVASPPFMDLEQAVLPAVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVDDGSGS 2029
Query: 1855 PETPSRVGMK-VPTISVTSFHSQS---SYISSDNDSELEDADIKKELQSLREKHLKEISE 1910
P +P ++ K +P+ +++ S S SY+SSDN+S++ED D+K EL+ LR+KHLKEI +
Sbjct: 2030 PHSPHQLSSKSLPSQNLSQSLSNSFNSSYMSSDNESDIEDEDLKLELRRLRDKHLKEIQD 2089
Query: 1911 LQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVV 1970
LQS+QK EIE+LY +LGK +PP V AP +GRRR+ +KSK + L + +
Sbjct: 2090 LQSRQKHEIESLYTKLGK-VPPAVIIPPAAPLSGRRRRPTKSKGSKSSRSSSLGNKSPQL 2148
Query: 1971 ASSTGHLADSSRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSD-ICSGLA 2029
+G+L+ S P Q T G ++ Q Q ++ S SSD + S
Sbjct: 2149 ---SGNLSGQS-AASVLHPQQ-----TLHPPGNIPESGQNQLLQPLKPSPSSDNLYSAFT 2199
Query: 2030 SDGGGARGQGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSS 2089
SDG ++ S S P G+ SS ++
Sbjct: 2200 SDGA----------------ISVPSLSAP----------------------GQGTSSTNT 2221
Query: 2090 TSSLAPGPEPGPQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQL 2149
+ QP ++++KGTFTDDLHKLVD W + + + +
Sbjct: 2222 VGATVNSQAAQAQPPA-------MTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGS---- 2270
Query: 2150 KQTQKLQDMEAQAGWAAPGEARAMTAP 2176
+ + PG AR +AP
Sbjct: 2271 ---------KGHMNYEGPGMARKFSAP 2288
Score = 64.7 bits (156), Expect = 1e-09
Identities = 249/1151 (21%), Positives = 390/1151 (33%), Gaps = 225/1151 (19%)
Query: 1210 NHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMD-------------- 1255
+++ + F FDL+ D P+++A MVE ++ + + +T + +KD +
Sbjct: 518 DNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVRE 577
Query: 1256 ------KAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTG 1309
+ E L + + S G ++ G+ T + S
Sbjct: 578 EQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSAS--------------- 622
Query: 1310 KRWFIICPVAEHPAPEAPESSPPLPLSSLPPEAS--QDSAPYKDQLSSKEQPSFLASQQL 1367
V+ PE PE+ L P S D Q SS S ++SQQ
Sbjct: 623 --------VSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQT 674
Query: 1368 LSQA-------GPSNPPGAPPAPLAPSSPPVTALPQDGAA-------PATSTM------- 1406
+S PG P+ + S P P A P++S++
Sbjct: 675 VSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQ 734
Query: 1407 ----PEPASGTASQAGGPGTPQ------GLTSELETSQPLAETHEAPLAVQPLVVG--LA 1454
P+ G A T Q +SE T+QP+++ +AP + + G L
Sbjct: 735 PIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQP-QAPQVLPQVSAGKQLP 793
Query: 1455 PCTPAPEAASTRDASAPREPLPPPAPEPS---PHSGTPQPALGQ--PAPLLPA-AVGAVS 1508
P P + EP P A +PS HSG +GQ P PLLP V +
Sbjct: 794 VSQPVP--------TIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIP 845
Query: 1509 LATSQLPSPPLGPTVPP--------QPPSALESDG--EGPPPRVGFVDSTIKSLDEKLRT 1558
++T + + G + P QP L S P V S + +L + +
Sbjct: 846 ISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVSTVVPSQLPTLLQPVTQ 905
Query: 1559 LLYQEH------------VPTS-SASAGTPVEVGDRDFTLEPLR------GDQ---PRSE 1596
L Q H +P + +A P+ GD + P R GD P S
Sbjct: 906 LPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSNIAPSSN 965
Query: 1597 VCG----GDLALPPVPKEAVSGRVQLP---QPLVEKSELAPTRGA-----VMEQGTS-SS 1643
V + PP+P E ++ P QP VE + L P G V + G S +
Sbjct: 966 VASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGGVGGQVQVSQPGGSLAQ 1025
Query: 1644 MTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEP 1703
SS +++L + QVA V + Q + V+ D E
Sbjct: 1026 APTTSSQQAVLESTQGVSQVAPAEPVAVAQTQATQPTTLASSVDSAHSDVASGMSDGNEN 1085
Query: 1704 PPSDMGTVGGQAS---HPQTLGARALGSPRKRPEQQ--DVSSPAKTVGRFSVVSTQDEWT 1758
PS G G+ + + +++ +R+ RP+ + +VS+ V + T +
Sbjct: 1086 VPSSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQ-LETHNRKM 1144
Query: 1759 LASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGV---GEPVSSDSG--DEG 1813
+ L P ++ + D LA+ R + + E +S D EG
Sbjct: 1145 VTFKFDLDGDNPEEI--ATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEG 1202
Query: 1814 PRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTS- 1872
+ +Q + SGS +K ++P A S+ P ++G +PT S+T
Sbjct: 1203 DQGLESLQGKDDYGFSGS------QKLEGEFKQPIPASSM----PQQIG--IPTSSLTQV 1250
Query: 1873 FHSQSSYI------------SSDNDSELEDADIKKELQS--LREKHLKEISELQSQQKQE 1918
HS S SE+ D QS + H LQ +
Sbjct: 1251 VHSAGRRFIVSPVPESRLRESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSEL 1310
Query: 1919 IEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLA 1978
A PPN F HT PT S + + +S ++
Sbjct: 1311 RRAQMTEGPNTAPPN--FSHTG-PTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDIS 1367
Query: 1979 DSSRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQ 2038
S P + + A STG+ P S LSS + S
Sbjct: 1368 TSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTT 1427
Query: 2039 GWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPE 2098
++ PTS SS+ L V+VS SA S+ ST++
Sbjct: 1428 SPSLQVPTSTSEIVVSSTA-----LYPSVTVSATSA----------SAGGSTAT------ 1466
Query: 2099 PGPQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQD- 2157
PGP+P V Q S T T V TS A+QL L+ T L +
Sbjct: 1467 PGPKPPAVVSQQAAGSTTVGATLTS-----VSTTTSFPSTASQLSIQLSSSTSTPTLAET 1521
Query: 2158 -------MEAQAGWAAPGEARAMTAPRA----GVGMPRLPPAPGPLSTTVIPGA------ 2200
++ + + G A +++AP + G G+ PG L VIP
Sbjct: 1522 VVVSAHSLDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPI 1581
Query: 2201 APTLSVPTPDP 2211
P + PT P
Sbjct: 1582 LPQAAGPTSTP 1592
Score = 63.2 bits (152), Expect = 3e-09
Identities = 210/980 (21%), Positives = 325/980 (33%), Gaps = 185/980 (18%)
Query: 496 IEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRV----------ALIQWRRER 545
+ F FDL+ + P+E+A M+ + F + + +R+ + ++ ++
Sbjct: 1145 VTFKFDLDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQ 1204
Query: 546 IWPALQPKEQQDVGSPDKARG---PPVPLQ-------------VQVTYHAQAGQPGPPEP 589
+LQ K+ K G P+P QV + A P P
Sbjct: 1205 GLESLQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVP 1264
Query: 590 EEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQ--SVMLGSLADAAPSP 647
E + + P + ++A+ + G + + S S QQ S + + P+
Sbjct: 1265 ESRLRESKVFPSEI---TDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNT 1321
Query: 648 AQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPS------LQQHFPD 701
A S PV+P L S+ AA VPA + PP+ +Q
Sbjct: 1322 APPNFSHTGPTFPVVPPFLSSIAGVPTTAAA----TAPVPATSSPPNDISTSVIQSEVTV 1377
Query: 702 PA-MSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLP 760
P A V ST + T G P PP + P L+ + + + P VV + P L
Sbjct: 1378 PTEEGIAGV--ATSTGVVTSGGLPIPPVSESPVLS--SVVSSITIP-AVVSISTTSPSLQ 1432
Query: 761 PYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDL 820
+ + V + L P A P P AG + L +
Sbjct: 1433 VPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSV 1492
Query: 821 PTATVPPVPPPQ---YFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIV 877
T T P Q S + P+LA + ++ +L + L+ P +
Sbjct: 1493 STTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSS 1552
Query: 878 PNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMA-PTDVPPSPHHTVQNMR 936
P A + P G+ L I S +A P PQ A PT P
Sbjct: 1553 PG--AGVSSYISQPGGLHPLVIPSVIASTP-------ILPQAAGPTSTP----------- 1592
Query: 937 ATPPQPALPP--QPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPP 994
P P++PP QP V PQP L P P + QP P
Sbjct: 1593 LLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSD----TQPKAPG 1648
Query: 995 QPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSP-- 1052
+ E L+ E ++ A S + L V +PT V P+ +L+
Sbjct: 1649 IDDIKTLEEKLRSLFSEHSSSGAQHAS-VSLETSLVIESTVTPGIPTTAVAPSKLLTSTT 1707
Query: 1053 ---------PLPEVLLPAAPELLP-QFPSSLATVSASVQ------SVPTQTATLLP---- 1092
PL V LP P + P Q + ++T ++ V+ P A +LP
Sbjct: 1708 STCLPPTNLPLGTVALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTE 1767
Query: 1093 -PAN-------PPLPGGPGIASPCP-----------------TVQLTVEPVQE------E 1121
PA PP PG S P TV V PV
Sbjct: 1768 LPAGTLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAIT 1827
Query: 1122 QASQDKPPGLPQSCE------SYGGSDVTSGK-ELSDSCEGAFGGGRLEGRAARKHHRRS 1174
+A G+ Q E S G G+ ++S + +GA G+ + A+ H S
Sbjct: 1828 EAGTQPQKGVSQVKEGPVLATSSGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFES 1887
Query: 1175 TRARSRQERASRPRLTILNVCNTGDKM--VECQLETHNHKMVTFKFDLDGDAPDEIATYM 1232
+ + S +S P T++ G + + + HK + D P ++ +
Sbjct: 1888 STSESSVLSSSSPESTLVKPEPNGITIPGISSDVPESAHKTTASEAKSDTGQPTKVGRFQ 1947
Query: 1233 VEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESR 1292
V T + + + K ED +++ + P SPP +
Sbjct: 1948 V---------TTTANKVGRFSVSKTEDKITD----TKKEGPVASPPFMDL---------- 1984
Query: 1293 QSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLS--SLPPEASQDSAPYK 1350
QA P A P E PE S P L+ S PEA+ S
Sbjct: 1985 -EQAVLP-------------------AVIPKKEKPELSEPSHLNGPSSDPEAAFLSRDVD 2024
Query: 1351 DQLSSKEQPSFLASQQLLSQ 1370
D S P L+S+ L SQ
Sbjct: 2025 DGSGSPHSPHQLSSKSLPSQ 2044
Score = 32.3 bits (72), Expect = 5.3
Identities = 83/361 (22%), Positives = 111/361 (30%), Gaps = 73/361 (20%)
Query: 1520 GPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV--PTSSASAGTPVE 1577
GPT P PP G S + T + Q V PT AG
Sbjct: 1330 GPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVATS 1389
Query: 1578 VGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVME 1637
G V G L +PPV + P++ + T AV+
Sbjct: 1390 TG----------------VVTSGGLPIPPVSES----------PVLSSVVSSITIPAVVS 1423
Query: 1638 QGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAG 1697
T+S + S + V S + + PSV + AG
Sbjct: 1424 ISTTSPSLQVPTSTSEI--------VVSSTALYPSVTVSATS--------------ASAG 1461
Query: 1698 ESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEW 1757
S+A P P V QA+ T+GA S + + + T E
Sbjct: 1462 GSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAET 1521
Query: 1758 TLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVG-EPVSSDSGDEGPRA 1816
+ S HS LD+ S LA + +SS G G S G P
Sbjct: 1522 VVVSAHS----------LDKTSHSSTTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLV 1571
Query: 1817 RPPVQKQASLPVSGSVAGDFVKKATAFL-QRPSRAGSLGPETPSRVGMKVPTISVTSFHS 1875
P V AS P+ AG +T L Q PS + P VP + T HS
Sbjct: 1572 IPSV--IASTPILPQAAG---PTSTPLLPQVPSIPPLVQPVA------NVPAVQQTLIHS 1620
Query: 1876 Q 1876
Q
Sbjct: 1621 Q 1621
Score = 32.0 bits (71), Expect = 6.9
Identities = 38/147 (25%), Positives = 55/147 (37%), Gaps = 29/147 (19%)
Query: 1594 RSEVCGGD---LALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSP 1650
RS +C + L LP +P + LPQP + A + A E ++TA ++
Sbjct: 82 RSVICDSNATALELPGLP-------LSLPQPSIPA---AVPQSAPPEPHREETVTATAT- 130
Query: 1651 RSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGT 1710
S + + V P VP+ R G S EPPP+ G+
Sbjct: 131 -SQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVG----SKEEPPPARSGS 185
Query: 1711 VGGQASHPQTLGARALGSPRKRPEQQD 1737
GG A PQ +R +QQD
Sbjct: 186 GGGSAKEPQ----------EERSQQQD 202
Score = 31.6 bits (70), Expect = 9.1
Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 4/88 (4%)
Query: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDV 924
PG PL++P P+ PA +P A P +A +Q+ QP AA + A
Sbjct: 96 PGLPLSLP----QPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGP 151
Query: 925 PPSPHHTVQNMRATPPQPALPPQPTLPP 952
PS + + QP+L PP
Sbjct: 152 APSTVPSSTSKDRPVSQPSLVGSKEEPP 179
>gi|50845418 WNK lysine deficient protein kinase 3 isoform 1 [Homo
sapiens]
Length = 1800
Score = 663 bits (1711), Expect = 0.0
Identities = 377/600 (62%), Positives = 427/600 (71%), Gaps = 40/600 (6%)
Query: 170 RDEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDR 229
+++ E+E ++E ++KAVATS GRFLKFDIELGRG+FKTVYKGLDTETWVEVAWCELQDR
Sbjct: 122 KEKNEKEMEEEAEMKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDR 181
Query: 230 KLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKR 289
KLTK E+QRFKEEAEMLKGLQHPNIVRFYD WES KGK+CIVLVTELMTSGTLKTYLKR
Sbjct: 182 KLTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKR 241
Query: 290 FKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 349
FKVMKPKVLRSWCRQILKGL FLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATL
Sbjct: 242 FKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLM 301
Query: 350 RASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKV 409
R SFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKV
Sbjct: 302 RTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKV 361
Query: 410 TCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHG 469
T GIKPASF KV DPE+KEII CI +NK ER I+DLL+HAFFAEDTG+RVELAEED
Sbjct: 362 TSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRVELAEEDDC 421
Query: 470 RKSTIALRLWVEDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVA 529
S++ALRLWVEDPKKLKGK KDN AIEF+F+LE +TP+EVA EM++SGFFHESD K VA
Sbjct: 422 SNSSLALRLWVEDPKKLKGKHKDNEAIEFSFNLETDTPEEVAYEMVKSGFFHESDSKAVA 481
Query: 530 KSIRDRVALIQWRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEP 589
KSIRDRV I+ RE+ PA +E++D S K+ G P T Q E
Sbjct: 482 KSIRDRVTPIKKTREK-KPAGCLEERRD--SQCKSMGNVFPQPQNTTLPLAPAQQTGAEC 538
Query: 590 EEPEADQH----LLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAP 645
EE E DQH LL +S+ D+ ++G S ++SD+ SSQ SV S
Sbjct: 539 EETEVDQHVRQQLLQRKPQQHCSSVTGDNLSEAGAASVIHSDT-SSQPSVAYSSNQTMG- 596
Query: 646 SPAQCVCSPPVSEGPVLPQSLPS---LGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702
+Q V + P +E V Q S +G YQQ + LQ+H
Sbjct: 597 --SQMVSNIPQAEVNVPGQIYSSQQLVGHYQQVS-----------------GLQKHSKLT 637
Query: 703 AMSFAPVLPPPSTPMPT---GP-----GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQP 754
P++ ST +P GP Q +P Q P +P P V A Q L+P
Sbjct: 638 QPQILPLVQGQSTVLPVHVLGPTVVSQPQVSPLTVQKVPQIKPVSQP-VGAEQQAALLKP 696
Score = 150 bits (378), Expect = 2e-35
Identities = 164/627 (26%), Positives = 258/627 (41%), Gaps = 64/627 (10%)
Query: 982 PQPMLPPQPVLPPQPA----------LPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPY 1031
PQP P+ P Q VR + LQ P+Q + T + G +
Sbjct: 519 PQPQNTTLPLAPAQQTGAECEETEVDQHVRQQLLQ-RKPQQHCSSVTGDNLSEAGAASVI 577
Query: 1032 AVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQT-ATL 1090
D ++Q P+V + + + A + Q SS V Q Q + L
Sbjct: 578 HSDTSSQ-PSVAYSSNQTMGSQMVSNIPQAEVNVPGQIYSSQQLVGHYQQVSGLQKHSKL 636
Query: 1091 LPPANPPLPGGPGIASPC----PTV--QLTVEPVQEEQASQDKPPGLPQSCESYGG---- 1140
P PL G P PTV Q V P+ ++ Q KP P E
Sbjct: 637 TQPQILPLVQGQSTVLPVHVLGPTVVSQPQVSPLTVQKVPQIKPVSQPVGAEQQAALLKP 696
Query: 1141 -------SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILN 1193
DV + KE S + G G+ + R RR++ R E+ ++ +LT+L
Sbjct: 697 DLVRSLNQDVATTKENVSSPDNPSGNGKQD----RIKQRRASCPRP--EKGTKFQLTVLQ 750
Query: 1194 VCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDV 1253
V +GD MVECQLETHN+KMVTFKFD+DGDAP++IA YMVE +F+L++E+E F+E+++ +
Sbjct: 751 VSTSGDNMVECQLETHNNKMVTFKFDVDGDAPEDIADYMVEDNFVLESEKEKFVEELRAI 810
Query: 1254 MDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGK--R 1311
+ +A+++L +R + + ++ G+ E+ + + + ++ + R
Sbjct: 811 VGQAQEILHVHFATERATGVDSITVDSNSSQTGSSEQVQINSTSTQTSNESAPQSSPVGR 870
Query: 1312 W-FII-----------CPVAEHPAPEAPESSP-PLPLSSLPPEASQDSAPYKDQLSSKEQ 1358
W F I P +H P P P P ++ E S+D+ L+ +
Sbjct: 871 WRFCINQTIRNRETQSPPSLQHSMSAVPGRHPLPSPKNTSNKEISRDTL-----LTIENN 925
Query: 1359 PSFLASQQLLSQ-AGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQA 1417
P A S+ + + A + P + +D + T S
Sbjct: 926 PCHRALFTSKSEHKDVVDGKISECASVETKQPAILYQVEDNRQIMAPVTNSSSYSTTSVR 985
Query: 1418 GGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPP 1477
P +GLT + P+ H+ L+ T S + ++P
Sbjct: 986 AVPAECEGLTKQASIFIPVYPCHQTASQADALMSHPGESTQT-SGNSLTTLAFDQKPQTL 1044
Query: 1478 PAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEG 1537
+P+ + + Q + +P L PT QP + LESDGE
Sbjct: 1045 SVQQPAMDA----EFISQEGETTVNTEASSPKTVIPTQTPGLEPTT-LQPTTVLESDGE- 1098
Query: 1538 PPPRVGFVDSTIKSLDEKLRTLLYQEH 1564
PP++ F D+ IK+LDEKLR LLYQEH
Sbjct: 1099 RPPKLEFADNRIKTLDEKLRNLLYQEH 1125
Score = 71.6 bits (174), Expect = 8e-12
Identities = 43/95 (45%), Positives = 60/95 (63%), Gaps = 20/95 (21%)
Query: 1873 FHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIEALYRRLGK---- 1928
F+S SS +SSD++SE+ED D+K ELQ LREKH++E+ LQ+QQ +E++ LY RL
Sbjct: 1513 FYSPSSPMSSDDESEIEDEDLKVELQRLREKHIQEVVNLQTQQNKELQELYERLRSIKDS 1572
Query: 1929 -------PLPPNVGFFHTAPPTGRRRKTSKSKLKA 1956
PLPP A P RR ++ KSKL++
Sbjct: 1573 KTQSTEIPLPP-------ASP--RRPRSFKSKLRS 1598
Score = 63.5 bits (153), Expect = 2e-09
Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 2116 NKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEARAMTA 2175
+KKG FTDDLHKLVD+WT + VG + +KP+LNQLKQ+Q + E W E T
Sbjct: 1641 SKKGMFTDDLHKLVDDWTKEAVGNSLIKPSLNQLKQSQHKLETE---NWNKVSENTPSTM 1697
Query: 2176 PRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPT-PDPES 2213
+ L G + T++ G LS+P+ P P S
Sbjct: 1698 GYTSTWISSLSQIRGAVPTSLPQG----LSLPSFPGPLS 1732
Score = 32.3 bits (72), Expect = 5.3
Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 13/107 (12%)
Query: 1210 NHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVM--------DKAEDML 1261
+++ + F F+L+ D P+E+A MV+ F +++ + + ++D + K L
Sbjct: 444 DNEAIEFSFNLETDTPEEVAYEMVKSGFFHESDSKAVAKSIRDRVTPIKKTREKKPAGCL 503
Query: 1262 SEDTDADRGSDPGTSP-PHLSTCGLG----TGEESRQSQANAPVYQQ 1303
E D+ S P P +T L TG E +++ + V QQ
Sbjct: 504 EERRDSQCKSMGNVFPQPQNTTLPLAPAQQTGAECEETEVDQHVRQQ 550
Score = 32.3 bits (72), Expect = 5.3
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 492 DNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 540
+N + F FD++ + P+++A M+E F ES+ + + +R V Q
Sbjct: 767 NNKMVTFKFDVDGDAPEDIADYMVEDNFVLESEKEKFVEELRAIVGQAQ 815
>gi|50845416 WNK lysine deficient protein kinase 3 isoform 2 [Homo
sapiens]
Length = 1743
Score = 663 bits (1711), Expect = 0.0
Identities = 377/600 (62%), Positives = 427/600 (71%), Gaps = 40/600 (6%)
Query: 170 RDEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDR 229
+++ E+E ++E ++KAVATS GRFLKFDIELGRG+FKTVYKGLDTETWVEVAWCELQDR
Sbjct: 122 KEKNEKEMEEEAEMKAVATSPSGRFLKFDIELGRGAFKTVYKGLDTETWVEVAWCELQDR 181
Query: 230 KLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTSGTLKTYLKR 289
KLTK E+QRFKEEAEMLKGLQHPNIVRFYD WES KGK+CIVLVTELMTSGTLKTYLKR
Sbjct: 182 KLTKAEQQRFKEEAEMLKGLQHPNIVRFYDSWESILKGKKCIVLVTELMTSGTLKTYLKR 241
Query: 290 FKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLK 349
FKVMKPKVLRSWCRQILKGL FLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATL
Sbjct: 242 FKVMKPKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLM 301
Query: 350 RASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKV 409
R SFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKV
Sbjct: 302 RTSFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKV 361
Query: 410 TCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHG 469
T GIKPASF KV DPE+KEII CI +NK ER I+DLL+HAFFAEDTG+RVELAEED
Sbjct: 362 TSGIKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLNHAFFAEDTGLRVELAEEDDC 421
Query: 470 RKSTIALRLWVEDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVA 529
S++ALRLWVEDPKKLKGK KDN AIEF+F+LE +TP+EVA EM++SGFFHESD K VA
Sbjct: 422 SNSSLALRLWVEDPKKLKGKHKDNEAIEFSFNLETDTPEEVAYEMVKSGFFHESDSKAVA 481
Query: 530 KSIRDRVALIQWRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEP 589
KSIRDRV I+ RE+ PA +E++D S K+ G P T Q E
Sbjct: 482 KSIRDRVTPIKKTREK-KPAGCLEERRD--SQCKSMGNVFPQPQNTTLPLAPAQQTGAEC 538
Query: 590 EEPEADQH----LLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAP 645
EE E DQH LL +S+ D+ ++G S ++SD+ SSQ SV S
Sbjct: 539 EETEVDQHVRQQLLQRKPQQHCSSVTGDNLSEAGAASVIHSDT-SSQPSVAYSSNQTMG- 596
Query: 646 SPAQCVCSPPVSEGPVLPQSLPS---LGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702
+Q V + P +E V Q S +G YQQ + LQ+H
Sbjct: 597 --SQMVSNIPQAEVNVPGQIYSSQQLVGHYQQVS-----------------GLQKHSKLT 637
Query: 703 AMSFAPVLPPPSTPMPT---GP-----GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQP 754
P++ ST +P GP Q +P Q P +P P V A Q L+P
Sbjct: 638 QPQILPLVQGQSTVLPVHVLGPTVVSQPQVSPLTVQKVPQIKPVSQP-VGAEQQAALLKP 696
Score = 192 bits (488), Expect = 3e-48
Identities = 266/1097 (24%), Positives = 429/1097 (39%), Gaps = 186/1097 (16%)
Query: 982 PQPMLPPQPVLPPQPA----------LPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPY 1031
PQP P+ P Q VR + LQ P+Q + T + G +
Sbjct: 519 PQPQNTTLPLAPAQQTGAECEETEVDQHVRQQLLQ-RKPQQHCSSVTGDNLSEAGAASVI 577
Query: 1032 AVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQT-ATL 1090
D ++Q P+V + + + A + Q SS V Q Q + L
Sbjct: 578 HSDTSSQ-PSVAYSSNQTMGSQMVSNIPQAEVNVPGQIYSSQQLVGHYQQVSGLQKHSKL 636
Query: 1091 LPPANPPLPGGPGIASPC----PTV--QLTVEPVQEEQASQDKPPGLPQSCESYGG---- 1140
P PL G P PTV Q V P+ ++ Q KP P E
Sbjct: 637 TQPQILPLVQGQSTVLPVHVLGPTVVSQPQVSPLTVQKVPQIKPVSQPVGAEQQAALLKP 696
Query: 1141 -------SDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILN 1193
DV + KE S + G G+ + R RR++ R E+ ++ +LT+L
Sbjct: 697 DLVRSLNQDVATTKENVSSPDNPSGNGKQD----RIKQRRASCPRP--EKGTKFQLTVLQ 750
Query: 1194 VCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDV 1253
V +GD MVECQLETHN+KMVTFKFD+DGDAP++IA YMVE +F+L++E+E F+E+++ +
Sbjct: 751 VSTSGDNMVECQLETHNNKMVTFKFDVDGDAPEDIADYMVEDNFVLESEKEKFVEELRAI 810
Query: 1254 MDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGK--R 1311
+ +A+++L +R + + ++ G+ E+ + + + ++ + R
Sbjct: 811 VGQAQEILHVHFATERATGVDSITVDSNSSQTGSSEQVQINSTSTQTSNESAPQSSPVGR 870
Query: 1312 W-FII-----------CPVAEHPAPEAPESSP-PLPLSSLPPEASQDSAPYKDQLSSKEQ 1358
W F I P +H P P P P ++ E S+D+ L+ +
Sbjct: 871 WRFCINQTIRNRETQSPPSLQHSMSAVPGRHPLPSPKNTSNKEISRDTL-----LTIENN 925
Query: 1359 PSFLASQQLLSQ-AGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQA 1417
P A S+ + + A + P + +D + T S
Sbjct: 926 PCHRALFTSKSEHKDVVDGKISECASVETKQPAILYQVEDNRQIMAPVTNSSSYSTTSVR 985
Query: 1418 GGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPP 1477
P +GLT + P+ H+ L+ T S + ++P
Sbjct: 986 AVPAECEGLTKQASIFIPVYPCHQTASQADALMSHPGESTQT-SGNSLTTLAFDQKPQTL 1044
Query: 1478 PAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEG 1537
+P+ + + Q + +P L PT QP + LESDGE
Sbjct: 1045 SVQQPAMDA----EFISQEGETTVNTEASSPKTVIPTQTPGLEPTT-LQPTTVLESDGE- 1098
Query: 1538 PPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEV 1597
PP++ F D+ IK+LDEKLR LLYQEH S S+ P D D P S
Sbjct: 1099 RPPKLEFADNRIKTLDEKLRNLLYQEH----SISSIYPESQKDTQSI------DSPFSSS 1148
Query: 1598 CGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYD 1657
L+ P A+S + V+ T ++ S A S P ++ +
Sbjct: 1149 AEDTLSCPVTEVIAIS-HCGIKDSPVQSPNFQQTGSKLL------SNVAASQPANISVFK 1201
Query: 1658 RDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASH 1717
R D +V+ SVP ++ + D G+ A P G +
Sbjct: 1202 R-------DLNVITSVPSEL-------CLHEMSSDASLPGDPEAYPAAVSSGGAIHLQTG 1247
Query: 1718 PQTLGARALGSPRKRPEQQDVSSPAKTV------------GRFSVVS-TQDEWTLASPHS 1764
+T R+ +P P ++ ++ + + GRF V++ Q + +
Sbjct: 1248 VETEEMRSAIAPDPIPLTRESTADTRALNRCKAMSGSFQRGRFQVITIPQQQSAKMTSFG 1307
Query: 1765 LRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQA 1824
+ + + V+ + SS + + ++Q IE P +S S ++ + ++
Sbjct: 1308 IEHIS---VFSETNHSSEEAFIKTAKSQLV-EIEPATQNPKTSFSYEKLQALQETCKENK 1363
Query: 1825 SLPVSG--------------------------SVAGDFVKKATAFLQR------------ 1846
+P G S G ++ + L +
Sbjct: 1364 GVPKQGDNFLSFSAACETDVSSVTPEKEFEETSATGSSMQSGSELLLKEREILTAGKQPS 1423
Query: 1847 ------PSRAGS------LGPET----PSRVGMKVPTISVTSFHSQSSYISSDNDSELED 1890
S AGS GPE+ P + F+S SS +SSD++SE+ED
Sbjct: 1424 SDSEFSASLAGSGKSVAKTGPESNQCLPHHEEQAYAQTQSSLFYSPSSPMSSDDESEIED 1483
Query: 1891 ADIKKELQSLREKHLKEISELQSQQKQEIEALYRRLGK-----------PLPPNVGFFHT 1939
D+K ELQ LREKH++E+ LQ+QQ +E++ LY RL PLPP
Sbjct: 1484 EDLKVELQRLREKHIQEVVNLQTQQNKELQELYERLRSIKDSKTQSTEIPLPP------- 1536
Query: 1940 APPTGRRRKTSKSKLKA 1956
A P RR ++ KSKL++
Sbjct: 1537 ASP--RRPRSFKSKLRS 1551
Score = 63.5 bits (153), Expect = 2e-09
Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 2116 NKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEARAMTA 2175
+KKG FTDDLHKLVD+WT + VG + +KP+LNQLKQ+Q + E W E T
Sbjct: 1584 SKKGMFTDDLHKLVDDWTKEAVGNSLIKPSLNQLKQSQHKLETE---NWNKVSENTPSTM 1640
Query: 2176 PRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPT-PDPES 2213
+ L G + T++ G LS+P+ P P S
Sbjct: 1641 GYTSTWISSLSQIRGAVPTSLPQG----LSLPSFPGPLS 1675
Score = 32.3 bits (72), Expect = 5.3
Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 13/107 (12%)
Query: 1210 NHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVM--------DKAEDML 1261
+++ + F F+L+ D P+E+A MV+ F +++ + + ++D + K L
Sbjct: 444 DNEAIEFSFNLETDTPEEVAYEMVKSGFFHESDSKAVAKSIRDRVTPIKKTREKKPAGCL 503
Query: 1262 SEDTDADRGSDPGTSP-PHLSTCGLG----TGEESRQSQANAPVYQQ 1303
E D+ S P P +T L TG E +++ + V QQ
Sbjct: 504 EERRDSQCKSMGNVFPQPQNTTLPLAPAQQTGAECEETEVDQHVRQQ 550
Score = 32.3 bits (72), Expect = 5.3
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 492 DNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQ 540
+N + F FD++ + P+++A M+E F ES+ + + +R V Q
Sbjct: 767 NNKMVTFKFDVDGDAPEDIADYMVEDNFVLESEKEKFVEELRAIVGQAQ 815
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 580 bits (1494), Expect = e-165
Identities = 346/667 (51%), Positives = 414/667 (62%), Gaps = 56/667 (8%)
Query: 34 ARPGPQRFLRRSVVESDQ--EEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARG 91
A P + + S E+D PP L A P PP RR + R + +R
Sbjct: 3 ASPATETTVLMSQTEADLALRPPPPLGTAGQPRLGPPPRRARRFSGKAEPRPRSSRLSR- 61
Query: 92 RPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGP----DPIAAAVETAPAPDGGPREEA 147
+ L++ P +PA P+P + PGP P + +G P + A
Sbjct: 62 --RSSVDLGLLSSWSLPASPAPDPPDPPDSAGPGPARSPPPSSKEPPEGTWTEGAPVKAA 119
Query: 148 AATVRKE--DEGAAEAKPEPGRT-------RRDEPEEEEDDEDDLKAVATSLDGRFLKFD 198
+ R E D EP R RR E EE+ED E +AVATS DGR+LKFD
Sbjct: 120 EDSARPELPDSAVGPGSREPLRVPEAVALERRREQEEKEDMET--QAVATSPDGRYLKFD 177
Query: 199 IELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFY 258
IE+GRGSFKTVY+GLDT+T VEVAWCELQ RKL++ ERQRF EE EMLKGLQHPNIVRFY
Sbjct: 178 IEIGRGSFKTVYRGLDTDTTVEVAWCELQTRKLSRAERQRFSEEVEMLKGLQHPNIVRFY 237
Query: 259 DFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPP 318
D W+S +G+ CIVLVTELMTSGTLKTYL+RF+ MKP+VL+ W RQIL+GL FLH+R PP
Sbjct: 238 DSWKSVLRGQVCIVLVTELMTSGTLKTYLRRFREMKPRVLQRWSRQILRGLHFLHSRVPP 297
Query: 319 IIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVD 378
I+HRDLKCDN+FITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEE YDE+VD
Sbjct: 298 ILHRDLKCDNVFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDEAVD 357
Query: 379 VYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNK 438
VYAFGMCMLEMATSEYPYSECQNAAQIYRKVT G KP SF KV PE+KEII CI +K
Sbjct: 358 VYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGRKPNSFHKVKIPEVKEIIEGCIRTDK 417
Query: 439 EERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWVEDPKKLKGKPKDNGAIEF 498
ER+ I+DLL+HAFF E+ GV VELAEED G K + L L +ED ++ G+P+DN AIEF
Sbjct: 418 NERFTIQDLLAHAFFREERGVHVELAEEDDGEKPGLKLWLRMEDARR-GGRPRDNQAIEF 476
Query: 499 TFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRERIWPALQPKEQQDV 558
F L ++ +EVAQEM+ G E+D + VA+++R+RVA IQ +RE++ A + +
Sbjct: 477 LFQLGRDAAEEVAQEMVALGLVCEADYQPVARAVRERVAAIQRKREKLRKARELEALPPE 536
Query: 559 GSPDKARGPPVPLQVQVTYHAQAGQPG--PPEPEEPEADQHLLPPTLPTSATSLASDSTF 616
P A P P G P PPEPEEPEADQH S +S SD
Sbjct: 537 PGPPPATVPMAP-----------GPPSVFPPEPEEPEADQHQPFLFRHASYSSTTSDCET 585
Query: 617 DSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQS---LPSLGAYQ 673
D S+ + D A PA PP L +S LPS A
Sbjct: 586 DGYLSSSGFLD----------------ASDPA---LQPPGGVPSSLAESHLCLPSAFALS 626
Query: 674 QPTAAPG 680
P + PG
Sbjct: 627 IPRSGPG 633
Score = 140 bits (352), Expect = 2e-32
Identities = 152/521 (29%), Positives = 209/521 (40%), Gaps = 96/521 (18%)
Query: 1037 AQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQ----TATLLP 1092
A VP P PP+ PP PE P A + P F A+ S++ T ++ L
Sbjct: 542 ATVPMAPGPPSVF--PPEPEE--PEADQHQP-FLFRHASYSSTTSDCETDGYLSSSGFLD 596
Query: 1093 PANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDS 1152
++P L G+ S L + + P +SY SD SG LSD
Sbjct: 597 ASDPALQPPGGVPSSLAESHLCLPSAFALSIPRSGPGSDFSPGDSYA-SDAASG--LSDV 653
Query: 1153 CEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNHK 1212
EG R GR R R R RL + +V + D++VECQL+THN K
Sbjct: 654 GEGMGQMRRPPGRNLR--------------RRPRSRLRVTSVSDQNDRVVECQLQTHNSK 699
Query: 1213 MVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRGSD 1272
MVTF+FDLDGD+P+EIA MV ++FIL +ER+ F+ ++++++ + E +L DT ++
Sbjct: 700 MVTFRFDLDGDSPEEIAAAMVYNEFILPSERDGFLRRIREIIQRVETLLKRDTGPMEAAE 759
Query: 1273 PGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPP 1332
SP E P AP + P
Sbjct: 760 DTLSP-----------------------------------------QEEP---APLPALP 775
Query: 1333 LPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSP-PV 1391
+PL E Q S +S E S+ A S G PG P +P P SP P+
Sbjct: 776 VPLPDPSNEELQSS-------TSLEHRSWTAFSTSSSSPGTPLSPGNPFSPGTPISPGPI 828
Query: 1392 TALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVV 1451
+ +P P P S +SQ +P +S L S + T E P+ +
Sbjct: 829 FPI----TSPPCHPSPSPFSPISSQVSSNPSPHPTSSPLPFS---SSTPEFPVPLSQCPW 881
Query: 1452 GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAA----VGAV 1507
P T P + T P PP P S T APLL A + +
Sbjct: 882 SSLPTTSPPTFSPTCSQVTLSSPFFPPCPSTSSFPST------TAAPLLSLASAFSLAVM 935
Query: 1508 SLATSQL-PSPPLGPTVPPQPPSALESDGEGPPPRVGFVDS 1547
++A S L PSP L PP PPS L S PP G +S
Sbjct: 936 TVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPVAPGGQES 976
Score = 82.8 bits (203), Expect = 3e-15
Identities = 129/513 (25%), Positives = 194/513 (37%), Gaps = 77/513 (15%)
Query: 1455 PCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQL 1514
P A + S ++ AP LP P P+PS +L + + + S T
Sbjct: 754 PMEAAEDTLSPQEEPAPLPALPVPLPDPSNEELQSSTSL-EHRSWTAFSTSSSSPGTPLS 812
Query: 1515 PSPPLGPTVP--PQPPSALESDGEGPPPR-VGFVDSTIKSLDEKLRTLLYQEHVPTSSAS 1571
P P P P P P + S P P + S + S T +P SS++
Sbjct: 813 PGNPFSPGTPISPGPIFPITSPPCHPSPSPFSPISSQVSSNPSPHPT---SSPLPFSSST 869
Query: 1572 AGTPVEVGDRDFTLEPLRGDQPRSEVCG----GDLALPPVPKEAVSGRVQLPQPLVEKSE 1627
PV + ++ P S C PP P + S
Sbjct: 870 PEFPVPLSQCPWSSLPTTSPPTFSPTCSQVTLSSPFFPPCPSTS--------------SF 915
Query: 1628 LAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVE 1687
+ T ++ ++ S+ + +S+L S P+ P +P+ P V
Sbjct: 916 PSTTAAPLLSLASAFSLAVMTVAQSLLS-----PSPGLLSQSPPAPPSPLPSLPLPPPVA 970
Query: 1688 PTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARAL-GSPRKRPEQQDVSSPAKTVG 1746
P GG+ E P V +AS P AR L G R P ++ + VG
Sbjct: 971 P----GGQ------ESPSPHTAEVESEASPPP---ARPLPGEARLAPISEE--GKPQLVG 1015
Query: 1747 RFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVS 1806
RF V S+++ A P L+ ++P L +P +L + T
Sbjct: 1016 RFQVTSSKEP---AEPLPLQPTSPT---LSGSPKPSTPQLTSESSDT------------- 1056
Query: 1807 SDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET-PSRVGMKV 1865
DS GP R + ++ G AG V++ + P GS P + PS V M
Sbjct: 1057 EDSAGGGPETREALA-ESDRAAEGLGAG--VEEEGDDGKEPQVGGSPQPLSHPSPVWMNY 1113
Query: 1866 PTISVTSFHSQSSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEIEALYRR 1925
+S S +++S ED + ELQSLR+KHL E+ LQ+ QK+EIE LY R
Sbjct: 1114 S-------YSSLCLSSEESESSGEDEEFWAELQSLRQKHLSEVETLQTLQKKEIEDLYSR 1166
Query: 1926 LGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGK 1958
LGK PP + A + R+R+ SK +
Sbjct: 1167 LGKQPPPGI-VAPAAMLSSRQRRLSKGSFPTSR 1198
Score = 72.0 bits (175), Expect = 6e-12
Identities = 92/350 (26%), Positives = 135/350 (38%), Gaps = 59/350 (16%)
Query: 668 SLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTP-MPTGPGQPAP 726
+L ++P P LPV +P P+ LQ S+ S+P P PG P
Sbjct: 761 TLSPQEEPAPLPALPV-PLPDPS-NEELQSSTSLEHRSWTAFSTSSSSPGTPLSPGNPFS 818
Query: 727 PGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQ 786
PG TP+ +P P+ P+ P H P +P S + + P P +
Sbjct: 819 PG---------TPI----SPGPIFPITSPPCHPSP--SPFSPISSQVSSNPSPHPTSSPL 863
Query: 787 PLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAP 846
P + P+ P VP L P +++P PP FSP +L++P
Sbjct: 864 PFSSSTPEFP----VP--------------LSQCPWSSLPTTSPPT-FSPTCSQVTLSSP 904
Query: 847 LPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAP-PGVAALSIHSAVAQ 905
P P+ P APL + + A T+ ++P PG+ + S + +
Sbjct: 905 FFPPCPS----TSSFPSTTAAPL-LSLASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSP 959
Query: 906 LPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPP-QPTLPP 964
LP P+ P P + PSPH A+PP PA P LP + L P P
Sbjct: 960 LPSLPLPPPVAPGGQES---PSPHTAEVESEASPP-PARP----LPGEARLAPISEEGKP 1011
Query: 965 QPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAA 1014
Q V Q T +P P P+ P P L P+P P L +++
Sbjct: 1012 QLVGRFQVTSSKEPA-------EPLPLQPTSPTLSGSPKPSTPQLTSESS 1054
Score = 63.9 bits (154), Expect = 2e-09
Identities = 101/376 (26%), Positives = 142/376 (37%), Gaps = 81/376 (21%)
Query: 496 IEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRERIWPALQPKEQ 555
+ F FDL+ ++P+E+A M+ + F S+ + IR+ + ++ +R ++ E
Sbjct: 701 VTFRFDLDGDSPEEIAAAMVYNEFILPSERDGFLRRIREIIQRVETLLKRDTGPMEAAE- 759
Query: 556 QDVGSPDKARGP----PVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLA 611
D SP + P PVPL P+P E S+TSL
Sbjct: 760 -DTLSPQEEPAPLPALPVPL---------------PDPSNEELQ----------SSTSLE 793
Query: 612 SDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAP-SPAQCVCSPPVSEGPVLPQSLPSLG 670
S T +S S SS + L+ P SP P+S GP+ P + P
Sbjct: 794 HRSW-------TAFSTSSSSPGT----PLSPGNPFSP-----GTPISPGPIFPITSPPCH 837
Query: 671 AYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQ 730
P + V S P+P S P P S P P P + P + P
Sbjct: 838 PSPSPFSPISSQVSSNPSPHPTSS-----PLPFSSSTPEFPVPLSQCPWS----SLPTTS 888
Query: 731 PPPLAQPTPLPQVLAPQPVVPLQPVPPHLP-PYLAPASQVGAPAQLKPLQMPQAPLQPLA 789
PP + PT QV P P P P AP + + L + + Q+ L P
Sbjct: 889 PPTFS-PT-CSQVTLSSPFFPPCPSTSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSPSP 946
Query: 790 QVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPA---VILPSLAAP 846
+ Q PP P P LP LP PPV P SP+ + S A+P
Sbjct: 947 GLLSQSPPAP--------------PSPLPSLPLP--PPVAPGGQESPSPHTAEVESEASP 990
Query: 847 LPPASPALPLQAVKLP 862
PPA P LP +A P
Sbjct: 991 -PPARP-LPGEARLAP 1004
Score = 61.2 bits (147), Expect = 1e-08
Identities = 87/341 (25%), Positives = 119/341 (34%), Gaps = 74/341 (21%)
Query: 803 PITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLP 862
P TPL+ + P P P P PP + SP +P P S + + P
Sbjct: 807 PGTPLSPGNPFSPGTPISPGPIFPITSPPCHPSP--------SPFSPISS--QVSSNPSP 856
Query: 863 HPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPT 922
HP +PL P + P P +PL +Q P + PT
Sbjct: 857 HPTSSPL--PFSSSTPEFP--VPL-----------------SQCPWSSL---------PT 886
Query: 923 DVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPP 982
PP+ T + T P PP P+ P P L Q +L P
Sbjct: 887 TSPPTFSPTCS--QVTLSSPFFPPCPSTSSFPSTTAAPLLSLASAFSLAVMTVAQSLLSP 944
Query: 983 QP-MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPT 1041
P +L P PP P LP P P P PG Q P+P+ +V ++
Sbjct: 945 SPGLLSQSPPAPPSP-LPSLPLP----------PPVAPGGQ---ESPSPHTAEVESEASP 990
Query: 1042 VPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGG 1101
P P P L P + E PQ S+ + P L P +P L G
Sbjct: 991 PPARPL-----PGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLP----LQPTSPTLSGS 1041
Query: 1102 PGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSD 1142
P ++P QLT E ++D G P++ E+ SD
Sbjct: 1042 PKPSTP----QLT----SESSDTEDSAGGGPETREALAESD 1074
Score = 56.6 bits (135), Expect = 3e-07
Identities = 85/333 (25%), Positives = 119/333 (35%), Gaps = 50/333 (15%)
Query: 847 LPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQL 906
L P PL A+ +P P + + T + + T + + PG LS + +
Sbjct: 762 LSPQEEPAPLPALPVPLPDPSNEELQSSTSLEHRSWTAFSTSSSSPGTP-LSPGNPFS-- 818
Query: 907 PGQPVYPAA-FPQMAPTDVP-PSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPP 964
PG P+ P FP +P P PSP + + ++ P P PT P LP + P
Sbjct: 819 PGTPISPGPIFPITSPPCHPSPSPFSPISSQVSSNPSP----HPTSSP---LPFSSSTPE 871
Query: 965 QPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAA-PAATPGSQI 1023
PV Q P P P P + P P P ++ P+ T +
Sbjct: 872 FPVPLSQCPWSSLPTTSP-------PTFSPTCSQVTLSSPFFPPCPSTSSFPSTTAAPLL 924
Query: 1024 LLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSV 1083
L AV AQ P P SPP P LP+ P P P + S V
Sbjct: 925 SLASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPVAPGGQESPSPHTAEV 984
Query: 1084 PTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEE---------QASQDKPPGLP-- 1132
++ + PP PLPG +A P+ EE Q + K P P
Sbjct: 985 ESEAS---PPPARPLPGEARLA-----------PISEEGKPQLVGRFQVTSSKEPAEPLP 1030
Query: 1133 --QSCESYGGSDVTSGKEL---SDSCEGAFGGG 1160
+ + GS S +L S E + GGG
Sbjct: 1031 LQPTSPTLSGSPKPSTPQLTSESSDTEDSAGGG 1063
Score = 41.2 bits (95), Expect = 0.011
Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 17/117 (14%)
Query: 1321 HPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP 1380
H A E+SPP P LP EA AP +S + +P + Q+ S P A
Sbjct: 980 HTAEVESEASPP-PARPLPGEARL--AP----ISEEGKPQLVGRFQVTSSKEP-----AE 1027
Query: 1381 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQA-GGPGTPQGLTSELETSQPL 1436
P PL P+SP ++ P+ P+T + +S T A GGP T + L ++ L
Sbjct: 1028 PLPLQPTSPTLSGSPK----PSTPQLTSESSDTEDSAGGGPETREALAESDRAAEGL 1080
Score = 39.7 bits (91), Expect = 0.033
Identities = 41/141 (29%), Positives = 53/141 (37%), Gaps = 15/141 (10%)
Query: 974 RPPQPVLPPQPMLPPQPVLPPQPALPV-RPEPLQPHLPEQAAPAATPGSQILLGHPAPYA 1032
R P+ + L PQ P PALPV P+P L S L H + A
Sbjct: 750 RDTGPMEAAEDTLSPQEEPAPLPALPVPLPDPSNEELQ----------SSTSLEHRSWTA 799
Query: 1033 VDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLP---QFPSSLATVSASVQSVPTQTAT 1089
++ P P+ P SP P P P P PS + +S+ V S P+ T
Sbjct: 800 FSTSSSSPGTPLSPGNPFSPGTPISPGPIFPITSPPCHPSPSPFSPISSQVSSNPSPHPT 859
Query: 1090 LLP-PANPPLPGGPGIASPCP 1109
P P + P P S CP
Sbjct: 860 SSPLPFSSSTPEFPVPLSQCP 880
Score = 33.1 bits (74), Expect = 3.1
Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 15/100 (15%)
Query: 49 SDQEEPPGLEAAEAPGPQPP-QPLQRRVLLLCK--TRRLIAERARGRPAAPAPAALVAQP 105
S QEEP L A P P P + LQ L + T + + G P +P P
Sbjct: 763 SPQEEPAPLPALPVPLPDPSNEELQSSTSLEHRSWTAFSTSSSSPGTPLSP------GNP 816
Query: 106 GAPGAPADAGP-----EPVGTQEPGP-DPIAAAVETAPAP 139
+PG P GP P P P PI++ V + P+P
Sbjct: 817 FSPGTPISPGPIFPITSPPCHPSPSPFSPISSQVSSNPSP 856
Score = 32.3 bits (72), Expect = 5.3
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 11/78 (14%)
Query: 707 APVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQ-PVPPHLPPYLAP 765
+P PP P GPG P + PPP ++ P PV + P LP
Sbjct: 78 SPAPDPPDPPDSAGPG----PARSPPPSSKEPPEGTWTEGAPVKAAEDSARPELPD---- 129
Query: 766 ASQVGAPAQLKPLQMPQA 783
S VG P +PL++P+A
Sbjct: 130 -SAVG-PGSREPLRVPEA 145
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 162 bits (409), Expect = 4e-39
Identities = 192/651 (29%), Positives = 261/651 (40%), Gaps = 122/651 (18%)
Query: 501 DLEKETP---DEVAQ--EMIESGFFHESDVKIVAKSIRDRVALIQWRRERIWPA----LQ 551
+LE++ P EVA + +E+G DV + A + ++ + R RI A
Sbjct: 692 ELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEK----EVRHHRILEAKSIQTS 747
Query: 552 PKEQQDV-------GSPDKARGPP-VPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTL 603
P E+ V G P + PP Q + ++ P + D H PT
Sbjct: 748 PTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSH--QPTQ 805
Query: 604 PTSATSLASDSTFDSGQGS-------TVYSDSQSSQQSVMLGSLADAA--PSPAQCVCSP 654
S + +GQG ++ ++ Q+S + + + ++ PSP C+
Sbjct: 806 SISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE 865
Query: 655 PVSEGPVLPQSLPSLGAYQQPTAA-PGLPVGSVPAPACP--PSLQQHF----PDPAMSFA 707
S S+P LG P PG+ V ++P+ A P P LQ P P + A
Sbjct: 866 SSS-------SMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA 918
Query: 708 PVLPPPSTP------MPTGPGQPAPPGQQPPPL-----AQPTPLPQVLAP-QPVVPLQPV 755
+ PPP P +P PG PP PPPL P PLP P P +P +
Sbjct: 919 GIPPPPPLPGAGILPLPPLPGAGIPP---PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975
Query: 756 PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIP--VVPPITPLAGIDGL 813
PP PP L P + + P L +P P P A +PP PP+P +PP PL G G+
Sbjct: 976 PP--PPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGA-GI 1030
Query: 814 PPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPC 873
PP P LP A +PP PP LP P PP PL +P PP +P
Sbjct: 1031 PPP-PPLPGAGIPPPPP---------LPGAGIPPPP-----PLPGAGIPPPP----PLPG 1071
Query: 874 RTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQ 933
I P P +P + PP LPG + P P + +PP P
Sbjct: 1072 AGIPP--PPPLPGAGIPPP-----------PPLPGAGIPPP--PPLPGVGIPPPPPLPGA 1116
Query: 934 NMRATPPQP--ALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPV 991
+ PP P +PP P LP + PP P P+ +PP P P + PP P+ P
Sbjct: 1117 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PRVGIPPPPPLPGAGIPPPPPL--PGAG 1172
Query: 992 LPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLS 1051
+PP P LP P P LP P P + P P P P+PP
Sbjct: 1173 IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGI 1232
Query: 1052 PPLPEVLLPAAPELLPQFPSSLATVSASVQSVPT-QTATLLPPANPPLPGG 1101
PP P +L + P LLPQ SS ++PT Q LP PPLP G
Sbjct: 1233 PP-PPLLPVSGPPLLPQVGSS---------TLPTPQVCGFLP---PPLPSG 1270
Score = 61.2 bits (147), Expect = 1e-08
Identities = 75/282 (26%), Positives = 95/282 (33%), Gaps = 42/282 (14%)
Query: 1273 PGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPP 1332
PG+ PPH + T E S A ++ + C + P ESS
Sbjct: 825 PGSQPPHSISTEFQTSHEHSVSSA----FKNS-----------CNIPSPPPLPCTESSSS 869
Query: 1333 LPLSSL----PPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSS 1388
+P + PP + P + + P ++ L P G PP P P +
Sbjct: 870 MPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGA 929
Query: 1389 P--PVTALPQDGAAPATSTMPEPASGTASQ-------AGGPGTPQGLTSELETSQPLAET 1439
P+ LP G P P P G A AG P P + + PL
Sbjct: 930 GILPLPPLPGAGIPP-----PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA 984
Query: 1440 HEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL 1499
P P G+ P P P A P +PPP P P P P G P
Sbjct: 985 GIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1043
Query: 1500 LPAAVGAVSLATSQLPSPPL-GPTVPPQPPSALESDGEGPPP 1540
P GA P PPL G +PP PP L G PPP
Sbjct: 1044 PPPLPGA-----GIPPPPPLPGAGIPPPPP--LPGAGIPPPP 1078
Score = 58.9 bits (141), Expect = 5e-08
Identities = 68/248 (27%), Positives = 83/248 (33%), Gaps = 43/248 (17%)
Query: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLS-SKEQPSFLASQ-----QLLSQAGPSN 1375
P P ES P S E S +P + + QP+ SQ LL AG
Sbjct: 768 PCPPGAESGPQTKFCS---EISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQ 824
Query: 1376 PPGAPPAPLA---------------------PSSPPVTALPQDGAAPATSTMPEPASGTA 1414
P PP ++ PS PP+ + P +P P
Sbjct: 825 PGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLP 884
Query: 1415 SQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLV-VGLAPCTPAPEAASTRDASAPRE 1473
G P ++ + PL T P PL G+ P P P A P
Sbjct: 885 ----GMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGA 940
Query: 1474 PLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPL-GPTVPPQPPSALE 1532
+PPP P P P P G PL P GA P PPL G +PP PP L
Sbjct: 941 GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA-----GIPPPPPLPGAGIPPPPP--LP 993
Query: 1533 SDGEGPPP 1540
G PPP
Sbjct: 994 GAGIPPPP 1001
Score = 56.6 bits (135), Expect = 3e-07
Identities = 62/216 (28%), Positives = 72/216 (33%), Gaps = 26/216 (12%)
Query: 1327 PESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAP 1386
P PPLP + +PP A + L AG PP P A + P
Sbjct: 909 PPPPPPLPGAGIPPPPPLPGAG-------------ILPLPPLPGAGIPPPPPLPGAAIPP 955
Query: 1387 SSP-PVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLA 1445
P P +P P P P AG P P + + PL P
Sbjct: 956 PPPLPGAGIPLPPPLPGAGIPPPPP---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1012
Query: 1446 VQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVG 1505
P G+ P P P A P +PPP P P P P G P P G
Sbjct: 1013 PLP-GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071
Query: 1506 AVSLATSQLPSPPL-GPTVPPQPPSALESDGEGPPP 1540
A P PPL G +PP PP L G PPP
Sbjct: 1072 A-----GIPPPPPLPGAGIPPPPP--LPGAGIPPPP 1100
Score = 55.8 bits (133), Expect = 4e-07
Identities = 79/287 (27%), Positives = 95/287 (33%), Gaps = 38/287 (13%)
Query: 1322 PAPEAPESS----PPLPLSSLPPEASQDSA--PYKDQLSSKEQPSFLASQQLLSQAGPSN 1375
P P P + PPLP + +PP A P L P L AG
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP----PPPLPGAGIPP 1087
Query: 1376 PP-----GAPPAPLAPSS--PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTS 1428
PP G PP P P PP LP G P P P G AG P P +
Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP-----PPPLPG----AGIPPPPPLPGA 1138
Query: 1429 ELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGT 1488
+ PL P P G+ P P P A P +PPP P P
Sbjct: 1139 GIPPPPPLPRVGIPPPPPLP-GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP 1197
Query: 1489 PQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP--PRVGFVD 1546
P P G P P G P PP G +PP P + GPP P+VG
Sbjct: 1198 PPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPV----SGPPLLPQVG--- 1250
Query: 1547 STIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQP 1593
+L +P+ G + G R +EP R +P
Sbjct: 1251 --SSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKP 1295
Score = 49.3 bits (116), Expect = 4e-05
Identities = 70/271 (25%), Positives = 97/271 (35%), Gaps = 65/271 (23%)
Query: 1386 PSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLA 1445
P++PP PQ GA SG A +A PG+P +T Q L+ + P +
Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEA--PGSP-------DTEQALSALSDLPES 282
Query: 1446 VQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVG 1505
+ A+ PREP PP+P P S P QPA
Sbjct: 283 L---------------------AAEPREPQQPPSPGGLPVSEAPSLPAAQPA-------A 314
Query: 1506 AVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV 1565
S +++ P P GP + G P R G D+ + ++ E
Sbjct: 315 KDSPSSTAFPFPEAGP----------GEEAAGAPVR-GAGDTDEEGEEDAF------EDA 357
Query: 1566 PTSSASAGTPVEVGDRDFTLEPLR-GDQPRSEVCGGD----LALPPVPKEAVSGRVQLPQ 1620
P S EVG+ P R G++P E G D +LP P A S R P
Sbjct: 358 PRGSPGEEWAPEVGED----APQRLGEEPEEEAQGPDAPAAASLPGSP--APSQRCFKPY 411
Query: 1621 PLVEKSELAPTRGAVMEQGTSSSMTAESSPR 1651
PL+ + T + S S + SPR
Sbjct: 412 PLITPCYIKTTTRQLSSPNHSPSQSPNQSPR 442
Score = 48.5 bits (114), Expect = 7e-05
Identities = 60/214 (28%), Positives = 77/214 (35%), Gaps = 42/214 (19%)
Query: 939 PPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTR---------PPQPVLPPQPMLPP- 988
PP LP +P PP PQ + L P R P Q + P P PP
Sbjct: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPP--PPS 815
Query: 989 ------QPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVP-- 1040
Q QP + E H E + +A S + P + ++ +P
Sbjct: 816 LLWSAGQGQPGSQPPHSISTEFQTSH--EHSVSSAFKNSCNIPSPPPLPCTESSSSMPGL 873
Query: 1041 -TVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLP 1099
VP PP PPLP + +P P +A Q P Q +LPP PPLP
Sbjct: 874 GMVPPPP-----PPLPGMTVPTLPS------------TAIPQPPPLQGTEMLPPPPPPLP 916
Query: 1100 GGPGIASPCPTVQLTVEPVQE-EQASQDKPPGLP 1132
G GI P P + P+ A PP LP
Sbjct: 917 GA-GIPPPPPLPGAGILPLPPLPGAGIPPPPPLP 949
Score = 42.0 bits (97), Expect = 0.007
Identities = 56/207 (27%), Positives = 73/207 (35%), Gaps = 56/207 (27%)
Query: 1377 PGAPPAPLAPSSPPVT---------------ALPQDGAAPATSTM---PEPASGTASQAG 1418
PG PP P S P T ++ D P S P P+ ++ G
Sbjct: 764 PGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQG 823
Query: 1419 GPGT--PQGLTSELETSQPLAETHEAPLAVQPLV-VGLAPCTPAPEAASTRDASAPREPL 1475
PG+ P +++E +TS H A + + P P E++S+ P
Sbjct: 824 QPGSQPPHSISTEFQTSHE----HSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP 879
Query: 1476 PPPAP-------------EPSPHSGT--------PQPALGQPAPLLPAAVGAVSLATSQL 1514
PPP P +P P GT P P G P P P GA L
Sbjct: 880 PPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP--PPLPGA-----GIL 932
Query: 1515 PSPPLGPT-VPPQPPSALESDGEGPPP 1540
P PPL +PP PP L PPP
Sbjct: 933 PLPPLPGAGIPPPPP--LPGAAIPPPP 957
Score = 40.4 bits (93), Expect = 0.020
Identities = 60/242 (24%), Positives = 86/242 (35%), Gaps = 17/242 (7%)
Query: 1289 EESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAP 1348
++ +Q Q QQ G P A P P A L +P
Sbjct: 208 QQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSP 267
Query: 1349 YKDQLSS--KEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTM 1406
+Q S + P LA++ Q PS PG P APS P +D +P+++
Sbjct: 268 DTEQALSALSDLPESLAAEPREPQQPPS--PGGLPVSEAPSLPAAQPAAKD--SPSSTAF 323
Query: 1407 PEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTR 1466
P P +G +A G ++ E + E +AP G E A R
Sbjct: 324 PFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFE--DAPRGSP----GEEWAPEVGEDAPQR 377
Query: 1467 DASAPREPLP-PPAPEPSPHSGTPQPA--LGQPAPLLPAAVGAVSLATSQLPSPPLGPTV 1523
P E P AP + G+P P+ +P PL+ + T QL SP P+
Sbjct: 378 LGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCY--IKTTTRQLSSPNHSPSQ 435
Query: 1524 PP 1525
P
Sbjct: 436 SP 437
Score = 36.6 bits (83), Expect = 0.28
Identities = 60/242 (24%), Positives = 79/242 (32%), Gaps = 34/242 (14%)
Query: 729 QQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPL 788
QQ +P P ++PQP L L P G+P + L + L
Sbjct: 224 QQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESL 283
Query: 789 AQVP--PQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAP 846
A P PQ PP P P++ + PA D P++T P P A P
Sbjct: 284 AAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPE-------------AGP 330
Query: 847 LPPASPALPLQAVKLPHPPG-------APLAMPCRTIVPNAPATIP-LLAVAPPGVAALS 898
A+ A P++ G AP P P P L P A
Sbjct: 331 GEEAAGA-PVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGP 389
Query: 899 IHSAVAQLPGQPV--------YPAAFPQMAPTDVP--PSPHHTVQNMRATPPQPALPPQP 948
A A LPG P YP P T SP+H+ P+ P+P
Sbjct: 390 DAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEP 449
Query: 949 TL 950
+L
Sbjct: 450 SL 451
Score = 36.2 bits (82), Expect = 0.37
Identities = 51/177 (28%), Positives = 65/177 (36%), Gaps = 22/177 (12%)
Query: 27 AEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIA 86
A P A + +PG L R ++ P A EAPG P Q L L A
Sbjct: 234 APPTAVSPQPGAFLGLDRFLLG------PSGGAGEAPGS--PDTEQALSALSDLPESLAA 285
Query: 87 ERAR--------GRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPA 138
E G P + AP+ AQP A +P+ P PG + A V A
Sbjct: 286 EPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTA-FPFPEAGPGEEAAGAPVRGAGD 344
Query: 139 PDGGPREEA---AATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVATSLDG 192
D E+A A +E A E + + +EPEEE D A SL G
Sbjct: 345 TDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPD--APAAASLPG 399
Score = 33.5 bits (75), Expect = 2.4
Identities = 54/211 (25%), Positives = 67/211 (31%), Gaps = 34/211 (16%)
Query: 584 PGPPEPEEPEADQHLLPPTLPTSA-------TSLASDSTFDSGQGSTVYSD--------- 627
PG P P E + + T+A TS SD+ S +T D
Sbjct: 144 PGGPGPAEARVGGRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAI 203
Query: 628 --SQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGS 685
Q QQ + L Q P V PQ LG + G G+
Sbjct: 204 RLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSG---GA 260
Query: 686 VPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLA 745
AP P + Q A+S LP P P QP PG P A P + A
Sbjct: 261 GEAPGSPDTEQ------ALSALSDLPESLAAEPREPQQPPSPGGLPVSEA-----PSLPA 309
Query: 746 PQPVVPLQPVPPHLP-PYLAPASQ-VGAPAQ 774
QP P P P P + GAP +
Sbjct: 310 AQPAAKDSPSSTAFPFPEAGPGEEAAGAPVR 340
Score = 32.7 bits (73), Expect = 4.1
Identities = 63/276 (22%), Positives = 94/276 (34%), Gaps = 40/276 (14%)
Query: 878 PNAPATIPLLAVAPPGVAALSIH-------SAVAQLPGQPVYPAAFPQMAPTDVPPSPHH 930
P AP T AV+P A L + + PG P A ++ D+P S
Sbjct: 232 PAAPPT----AVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALS--DLPES--- 282
Query: 931 TVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP 990
+ A P +P PP P P P P P P T P P P P
Sbjct: 283 ----LAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAP 338
Query: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQIL--LGHPAPYAV----DVAAQVPTVPV 1044
V + A E + + AP +PG + +G AP + + AQ P P
Sbjct: 339 V---RGAGDTDEEGEEDAFED--APRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPA 393
Query: 1045 PPAAVLSPPLPEVLLPAAPELLPQF----PSSLATVSASVQSVPTQTATLLPPANPPLPG 1100
+ SP + P + P + L++ + S P Q+ + P L
Sbjct: 394 AASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSR 453
Query: 1101 GPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCE 1136
G A + P ++ +A GL +S +
Sbjct: 454 GSRTA-----LASVAAPAKKHRADGGLAAGLSRSAD 484
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 152 bits (385), Expect = 3e-36
Identities = 176/589 (29%), Positives = 221/589 (37%), Gaps = 94/589 (15%)
Query: 598 LLPPTLPTSATSLASDSTFDSG--QGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPP 655
L P P + +SL + ++ S Q + + Q L S + A +P SPP
Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD---SPP 456
Query: 656 VSEGPVLPQSLPSLGAYQQPTAAP-GLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPS 714
+ LP S P L P +P P+ P A SL H P +S + ++PP
Sbjct: 457 LQAPLSLPAS-PPLQTSLSPAVSPLSSPLTIHPLQALS-SLASHSPQAPLS-SLIMPPLE 513
Query: 715 TPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQ 774
T APP Q PP + TP PL+ +P PP L AS AP
Sbjct: 514 TQSSL-----APPSLQTPPASLTTP-----------PLENLPSLAPPPLQTAS---APLT 554
Query: 775 LKPLQMP--------QAPLQPLAQVPPQMP-----PIPVVPPITPLAGIDGLPPALPDLP 821
L+ P QAP PL PP+ P P P PP + GLP P P
Sbjct: 555 TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP-PLSP 613
Query: 822 TATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGA--------PLAMPC 873
AT PP PP P P A P PPASP L A P P A P + P
Sbjct: 614 LATPPPQAPPXLALP----PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP- 668
Query: 874 RTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQ 933
P+ P P A P V S A P Q A P P VPPSP
Sbjct: 669 ----PSPPVQAPFSPPASPPV------SPSATPPSQAPPSLAAP---PLQVPPSP----- 710
Query: 934 NMRATPP-QPALPPQPTLPPQPVLPPQPTLPPQPVLPP-QPTRPPQPVLPPQPMLPPQPV 991
A+PP P+ P P PP PP P P PP P+ P P +PP PP V
Sbjct: 711 --PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768
Query: 992 LPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLS 1051
PP P + PL P+ ATP Q L PA + A P+ +P + + +
Sbjct: 769 -PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLPMSPLAT 826
Query: 1052 PPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTV 1111
PP PQ P LA V P + TL P PP P GP + P +
Sbjct: 827 PP-------------PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPRL 872
Query: 1112 QLTVEPVQEEQASQDKPPGLP-QSCESYGGSDVTSGKELSDSCEGAFGG 1159
L + P S+ L + S ++ +EL G GG
Sbjct: 873 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921
Score = 137 bits (346), Expect = 9e-32
Identities = 172/644 (26%), Positives = 225/644 (34%), Gaps = 100/644 (15%)
Query: 549 ALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTL-PTSA 607
AL ++D P P + + G P P P PPT P +
Sbjct: 155 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR------PPTEGPRKS 208
Query: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLP 667
S AS+ +S ++ S + S PA S + +S P
Sbjct: 209 VSSASE-----------HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 668 SLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPP-STPMPTGP-GQPA 725
S + A P P PP + D A + P+ P +TP P+G +P
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317
Query: 726 PPGQQ---PPPLAQPTPLPQVLAPQPVVP--------LQ--PVPPHLPPYLAPASQVGAP 772
PP P P P P P + P P+ P LQ P PP PP AP S P
Sbjct: 318 PPPDNAATPLPATLP-PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
Query: 773 AQ-------LKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATV 825
Q + P+Q+P + P Q PP + + T L P L
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS--------PTLQATHS 428
Query: 826 PPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNA--PAT 883
P+ ++ PS A PP SP PLQA P P + P +T + A P +
Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSP--PLQA-----PLSLPASPPLQTSLSPAVSPLS 481
Query: 884 IPLLAVAPPGVAALSIHSAVAQL----------------PGQPVYPAA--------FPQM 919
PL +++L+ HS A L P PA+ P +
Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL 541
Query: 920 APTDVPPSPHHTVQNMRATPPQPA-----LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTR 974
AP + + TPP PA PP P P P P PP P PP
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP-PQAPPALAS 600
Query: 975 PPQPVLPPQPMLP---PQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPY 1031
PP LP P+ P P P PP ALP P P +P ATP Q AP
Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ------APN 654
Query: 1032 AVDV-AAQVPTVPVPPAAVLSPPLPEVLLPAAPELLP--QFPSSLATVSASVQSVPTQTA 1088
A+ V Q P P P V +P P P +P P Q P SLA V P +
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714
Query: 1089 TLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
+ P A PP P +A+P V + S PP +P
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
Score = 85.1 bits (209), Expect = 7e-16
Identities = 142/551 (25%), Positives = 191/551 (34%), Gaps = 66/551 (11%)
Query: 627 DSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP---VLPQSLPSLGAY----QQPTAAP 679
D++ + + AA +P PP S P V P +L LGA ++P A
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
Query: 680 GLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQ--PPPLAQP 737
+G P P S P PP++ G G+ APP + P P++ P
Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPAS----GRGERAPPAKNTSPGPVSSP 117
Query: 738 TPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP 797
P P+ + + +A AP + A + P P
Sbjct: 118 GRASGTTRPGPLGQ-KGLRISAEETVARGKATEAPKR----SALSAGARRDTSGPTPGTP 172
Query: 798 IPVVPPITPLAGID-GLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLP-------- 848
P + + AG + GLP P PP P+ + S P P
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPR--PPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
Query: 849 ------PASPALPLQAVKLPHPP-GAPLAM--PCRTIVPNAPATIPLLAVAPPGVAALSI 899
PAS +L A L P P A P P+ P L A+ PP V
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 900 HSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP-PQPVLPP 958
+A A P P A P + T P P + ATP LPP P L P P+ PP
Sbjct: 291 DAAPALGPLSSS-PLATPSPSGTKARPVPP---PDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 959 QPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQ---PVLPPQPALPVRPEPLQPHLPEQAAP 1015
P+ PP P P P PP PP P L P + V P L +P
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Query: 1016 AATPGSQIL--LGHP-----------APYAVDVAAQVPTVP--VPPAAVLSPPLPEVL-L 1059
A Q LG P +P + P+ P PP SPPL L L
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD---SPPLQAPLSL 463
Query: 1060 PAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEP-V 1118
PA+P L +++ +S+ + P Q + L +P P I P T P +
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 1119 QEEQASQDKPP 1129
Q AS PP
Sbjct: 524 QTPPASLTTPP 534
Score = 64.7 bits (156), Expect = 1e-09
Identities = 139/573 (24%), Positives = 177/573 (30%), Gaps = 142/573 (24%)
Query: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP-SNPPGAP 1380
P+ +AP S PL LSSL S S + S L S + P S PP +P
Sbjct: 398 PSLQAPPS--PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
Query: 1381 P--APLA-PSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLA 1437
P APL+ P+SPP+ Q +PA S + P + QA S L + P A
Sbjct: 456 PLQAPLSLPASPPL----QTSLSPAVSPLSSPLTIHPLQA---------LSSLASHSPQA 502
Query: 1438 ETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLP--------------------- 1476
+ L + PL + P+ + + P E LP
Sbjct: 503 PL--SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET 560
Query: 1477 PPAPEPSPHSGTPQP----------ALGQPAPLLPAAVGAVSLATSQLPSPPLGP--TVP 1524
PP P P P P P ++ P P P A+ + L LPSPPL P T P
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL--QGLPSPPLSPLATPP 618
Query: 1525 PQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFT 1584
PQ P L PP L P+ A V + F+
Sbjct: 619 PQAPPXLALPPLQAPP------------SPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 1585 LEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSM 1644
P P + A PPV A P S AP S M
Sbjct: 667 PPP----SPPVQAPFSPPASPPVSPSAT------PPSQAPPSLAAPPLQVPPSPPASPPM 716
Query: 1645 TAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPP 1704
+ ++P PQ P P P SA PP
Sbjct: 717 SPSATP----------------------PPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754
Query: 1705 PSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHS 1764
P P L A L P P +S AK Q LA+P
Sbjct: 755 P----------RVPPLLAAPPLQVPPSPPASLPMSPLAKP-------PPQAPPALATPPL 797
Query: 1765 LRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQA 1824
+PP + +AP SP L + T P PPV
Sbjct: 798 QALPSPPASFPGQAPFSPSASLPMSPLATP-------------------PPQAPPVLAAP 838
Query: 1825 SLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET 1857
L V S A+ LQ P R + GP+T
Sbjct: 839 LLQVPPS------PPASPTLQAPRRPPTPGPDT 865
Score = 64.7 bits (156), Expect = 1e-09
Identities = 99/395 (25%), Positives = 137/395 (34%), Gaps = 67/395 (16%)
Query: 1322 PAPEAPESSPPLPLSSLP-PEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP---- 1376
P P+AP + PL LP P S + P + P LA L QA PS P
Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATP------PPQAPPXLALPPL--QAPPSPPASPP 641
Query: 1377 --PGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQ 1434
P A P+P AP++ V L + P + + P S AS P + +
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701
Query: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALG 1494
P + +P A P+ TP P+A A + P PPA P S TP P +
Sbjct: 702 PPLQVPPSPPASPPM---SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV- 757
Query: 1495 QPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDE 1554
PLL A PPL VPP PP++L PP
Sbjct: 758 --PPLLAA--------------PPL--QVPPSPPASLPMSPLAKPP---------PQAPP 790
Query: 1555 KLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSE--VCGGDLALPPVP--KE 1610
L T Q ++ G + PL P++ + L +PP P
Sbjct: 791 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850
Query: 1611 AVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVV 1670
+ + P P + S P + G SP S L G +A S
Sbjct: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP--PPSRSPSSTL----SGPDLAGHSSSA 904
Query: 1671 PSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPP 1705
S P+++ + D G G ++A PPP
Sbjct: 905 TSTPEELRGY-----------DSGPEGGAAASPPP 928
Score = 55.8 bits (133), Expect = 4e-07
Identities = 132/602 (21%), Positives = 188/602 (31%), Gaps = 112/602 (18%)
Query: 1322 PAPEA----PESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF------LASQQLLSQA 1371
PAP A P P +SS ++ + +P +++ +PS AS+ L S A
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSP-----AARRRPSAGGGLQRPASRSLSSSA 246
Query: 1372 GPSNPP--------GAPPAPLAPSSP----------PVTALPQDGAAPATSTMPEPASGT 1413
P + P G P AP PS P P P+ AAPA + T
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 1414 ASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTP-----APEAASTRDA 1468
S +G P T P PLA + +P P P +T +
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366
Query: 1469 SAPREPLPPPAPEPS----------PHSGTPQPALGQPAPLLPAAVGAVSLATS------ 1512
AP PP P PHS T P+PL +++ A + S
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
Query: 1513 -------------QLPSPPLGPTVPP-QPPSALESDGEGPPPRVGFVDSTIKSLDEKLRT 1558
L SP + PP PP PP + + L L
Sbjct: 427 HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI 486
Query: 1559 LLYQEHVPTSSASAGTPVE-----VGDRDFTLEPLRGDQPRSEVCGGDL----ALPPVPK 1609
Q +S S P+ + +L P P + + L +L P P
Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Query: 1610 EAVSGRVQLPQ--------PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGR 1661
+ S + P P ++ +P E +S + +P ++ G
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606
Query: 1662 QVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTL 1721
S + PQ P P P A PP S + T QA P L
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPP--------SPPASPPLSPLATPSPQA--PNAL 656
Query: 1722 GARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSS 1781
L +P P V +P V + + A P +APP P+S
Sbjct: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP---SLAAPPLQVPPSPPAS 713
Query: 1782 PDVKLAVRRAQ------TASSIEVGVGEPVS---SDSGDEGPR-----ARPPVQKQASLP 1827
P + + A ++V P S S S PR A PP+Q S P
Sbjct: 714 PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773
Query: 1828 VS 1829
S
Sbjct: 774 AS 775
Score = 53.5 bits (127), Expect = 2e-06
Identities = 121/506 (23%), Positives = 168/506 (33%), Gaps = 112/506 (22%)
Query: 1370 QAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG----GPGTPQG 1425
+AGP+ G + P+S P + + A PA +T P P S +G GP +G
Sbjct: 76 RAGPTRSAGT--SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 1426 LTSELETSQPLAETHEAP------LAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA 1479
L E + + EAP + G P TP+P A A+ LP PA
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
Query: 1480 PEPSPHSGTPQP----------ALGQPAPLL---PAAVGAV------SLATSQLP--SP- 1517
P P T P + +P+P P+A G + SL++S P SP
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 1518 ---------PLGPTVPPQP-PSALES--DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV 1565
P P P QP P L++ + PPR + L T
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT------- 306
Query: 1566 PTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEK 1625
P+ S + PV D T PL P S L L P A LP P
Sbjct: 307 PSPSGTKARPVPPPDNAAT--PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364
Query: 1626 SELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPAR 1685
AP SMT PS+ P V +
Sbjct: 365 PSQAP-----------PSMT------------------TPPMQAPPSLQTIPPIQVPHSL 395
Query: 1686 VEPTDRDGGEAGESSAEPPPSDMGTVGGQAS----HPQTLGARALGSPRKRPEQQDVSSP 1741
P S + PPS + QA+ P + + R Q ++SP
Sbjct: 396 TSP-----------SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
Query: 1742 AKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGV 1801
++ + D L +P SL S P L A S L + Q SS+
Sbjct: 445 SRPAS-----TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 1802 GE-PVSSDSGDEGPRARPPVQKQASL 1826
+ P+SS PP++ Q+SL
Sbjct: 500 PQAPLSS-------LIMPPLETQSSL 518
Score = 43.9 bits (102), Expect = 0.002
Identities = 100/432 (23%), Positives = 147/432 (34%), Gaps = 53/432 (12%)
Query: 1452 GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLAT 1511
G A TPA A P P PPP P+ PL A G + AT
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA-GGIGGAT 69
Query: 1512 SQLPSPPLGPT---------VPPQPPSA--------LESDGEGPPPRVGFVDSTIK--SL 1552
+P GPT +PP++ ++ GP G T + L
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 1553 DEKLRTLLYQEHVPTSSASAG---TPVEVGDRDFTLEPLRGDQP-----RSEVCGGDLAL 1604
+K + +E V A+ + + G R T P G RS G ++ L
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 1605 PPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVA 1664
P+ A S R + P KS A T S A P + G R +
Sbjct: 190 ---PRPAPSARPRPPTEGPRKS----VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 1665 SDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTV-GGQASHPQTLGA 1723
S S S PAR P+ R A ++P P + + Q + P+ A
Sbjct: 243 SSSATPLS---------SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 1724 RALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPD 1783
ALG P +++P+ + + V D P +L S P L AP SP
Sbjct: 294 PALGPLSSSP----LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349
Query: 1784 VKLAVRRAQTASSIEVGVGEPVSSDSGDEGP---RARPPVQKQASLPVSGSVAGDFVKKA 1840
+++ + + P + + P + PP+Q SL S S+ A
Sbjct: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL-TSPSLQAPPSPLA 408
Query: 1841 TAFLQRPSRAGS 1852
+ LQ + GS
Sbjct: 409 LSSLQATTSLGS 420
Score = 37.0 bits (84), Expect = 0.22
Identities = 37/142 (26%), Positives = 46/142 (32%), Gaps = 21/142 (14%)
Query: 11 PGTLMEPGRGAG---PAGM-----AEPRAKAARPGPQ-RFLRRSVVESDQEEPPGLEAAE 61
P P G G PA A P + AR GP R R+ Q +P GL+A
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 62 APGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGT 121
P PP+ L + L G A P P P D P+
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP------------PPDNAATPLPA 329
Query: 122 QEPGPDPIAAAVETAPAPDGGP 143
P P+A + AP P
Sbjct: 330 TLPPSPPLATPLPLAPPSPSAP 351
Score = 32.3 bits (72), Expect = 5.3
Identities = 44/166 (26%), Positives = 51/166 (30%), Gaps = 18/166 (10%)
Query: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQP 70
P L P P+ A P +A R P SV P L A APGP PP
Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV------SGPRLTLALAPGPPPPPS 885
Query: 71 LQRRVLLL-------CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQE 123
L + E RG + P A + P P A A ++
Sbjct: 886 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP--PDAELAACHPAAWSRG 943
Query: 124 PGPDPIAAAVETAP---APDGGPREEAAATVRKEDEGAAEAKPEPG 166
P P AP P GP E EG A P PG
Sbjct: 944 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 989
>gi|7019333 nuclear receptor binding protein [Homo sapiens]
Length = 535
Score = 151 bits (382), Expect = 6e-36
Identities = 102/299 (34%), Positives = 152/299 (50%), Gaps = 18/299 (6%)
Query: 163 PEPGRTRRDEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGS---FKTVYKGLDTETWV 219
P T PEEEE+ ED+ + + S GR+ K E+ + + + Y +DTE V
Sbjct: 33 PVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGV 92
Query: 220 EVAWCELQ--DRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTEL 277
EV W E+Q +RK KL+ ++ + + L L+H NIV+F+ +W + K ++ +TE
Sbjct: 93 EVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVIFITEY 152
Query: 278 MTSGTLKTYLKR----FKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITG 333
M+SG+LK +LK+ K M K + WC QIL L +LH+ PPIIH +L CD IFI
Sbjct: 153 MSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQ- 211
Query: 334 PTGSVKIGDLGLATL-KRASFAKSVIGTPEFMAPEMYE-EHYDESVDVYAFGMCMLEMAT 391
G +KIG + T+ + F APE E + +VD+Y+FGMC LEMA
Sbjct: 212 HNGLIKIGSVAPDTINNHVKTCREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAV 271
Query: 392 SEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSH 450
E N Y V ++ + + DP +E I +C+ R ++LL H
Sbjct: 272 LEIQ----GNGESSY--VPQEAISSAIQLLEDPLQREFIQKCLQSEPARRPTARELLFH 324
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 140 bits (353), Expect = 1e-32
Identities = 175/619 (28%), Positives = 227/619 (36%), Gaps = 83/619 (13%)
Query: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSA 607
P P S + A PP + + A+ PGP A P L
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS-SPGRASGTTRPGPLGQKG 133
Query: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAA------PSPAQCVCSPPVSEGPV 661
++++ T G+ + + ++ G+ D + PSPA S
Sbjct: 134 LRISAEETVARGKATEA-----PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 662 LPQSLPSLGAYQQPTAAPGLPVGSV-------PAPACP--PSLQQHFPDPAM-SFAPVLP 711
LP+ PS + PT P V S P+PA PS PA S +
Sbjct: 189 LPRPAPSARP-RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 712 PPSTPMPTGP---GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQ 768
P S+P +GP G P P P +P L + PQ P + P L P +S
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQP--KPKGLQALRPPQVTPPRKDAAPALGPL--SSSP 303
Query: 769 VGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPIT-----PLAGIDGLPPALPDLPTA 823
+ P+ P A LQ +Q PP +P P +T PL P A P L T
Sbjct: 304 LATPS-------PSAALQ--SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL 354
Query: 824 TVPPVPPPQYFSPAVILPSLAA-----PLPPASP-ALPLQAVKLPHPPGAP--LAMPCRT 875
PP PP + ++ P+L A P PP SP A P PP AP LA+P
Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP--------PPQAPPALALPPLQ 406
Query: 876 IVPNAPATIPLLAVAPPGVAA---LSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTV 932
P+ PA+ PL +A P A L++H A P P P P P SP T
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
Query: 933 QNMR----ATPPQPALPPQPTLPPQ-PVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLP 987
+ A PP P P PP P P P PP PP P P PP P
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526
Query: 988 PQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQ--------ILLGHPAPYAVDV--AA 1037
P LP PA P P +P ATP Q +L P+P A A
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586
Query: 1038 QVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP 1097
+ P P P +V P L L P P + PSS T+S + + +AT P
Sbjct: 587 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS--TLSGPDLAGHSSSATSTPEELRG 644
Query: 1098 LPGGP---GIASPCPTVQL 1113
GP ASP P +L
Sbjct: 645 YDSGPEGGAAASPPPDAEL 663
Score = 102 bits (254), Expect = 4e-21
Identities = 159/617 (25%), Positives = 230/617 (37%), Gaps = 97/617 (15%)
Query: 582 GQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLA 641
G P PP P P A + L +A ++ + G + +S+ ++ S
Sbjct: 31 GSPRPPPPVTPAALRVL------GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
Query: 642 DAAPSPAQCVCSPPVS-EGPVLPQSLPSLGAYQQPTAAPGLPVGSV-PAPACPPSLQQHF 699
++ +PA PP S G P P+ P ++PG G+ P P L+
Sbjct: 85 TSSRNPAS---RPPASGRGERAP---PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 700 PDPAMSFAPVLPPPSTPMPTGPGQPAP---PGQQPPPLAQPTPLP--QVLAPQPVVPLQP 754
+ P + + G + PG P +A+ + +V P+P +P
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198
Query: 755 VPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPI-PVVPPITPLAGIDGL 813
PP P + +S A P A +P A Q P + TPL+
Sbjct: 199 RPPTEGPRKSVSS---ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 814 PPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPAL-PLQAVKLPHPPGAPLAMP 872
P+ P A P P A+ P + P A+PAL PL + L P P
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS------P 309
Query: 873 CRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQM----APTDVPPSP 928
+ AP T+P A P ++L+ A LP P P+A P + +P PPS
Sbjct: 310 SAALQSQAPPTLP----ATPHSSSLTCQLATP-LPLAPPSPSAPPSLQTLPSPPATPPSQ 364
Query: 929 ------HHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPP-QPVLP 981
T+Q + P P L P T PPQ PP LPP P P PP P+
Sbjct: 365 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQA--PPALALPPLQAPPSPPASPPLSPLAT 422
Query: 982 PQPMLPP-------QPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVD 1034
P P P Q P P+ PV+ P P +P+ATP SQ AP ++
Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVSPSATPPSQ------APPSL- 474
Query: 1035 VAAQVPTVPVPPAAVLSPPLPEVLLP--------AAPELL-----PQFPSSLATVSASVQ 1081
P + VPP+ SPP+ P AAP L PQ P +LAT +Q
Sbjct: 475 ---AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT--PPLQ 529
Query: 1082 SVPTQTAT--------------LLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDK 1127
++P+ A+ + P A PP P +A+ P +Q+ P +
Sbjct: 530 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA--PLLQVPPSPPASPTLQAPR 587
Query: 1128 PPGLPQSCESYGGSDVT 1144
P P S G +T
Sbjct: 588 RPPTPGPDTSVSGPRLT 604
Score = 91.7 bits (226), Expect = 7e-18
Identities = 144/546 (26%), Positives = 179/546 (32%), Gaps = 125/546 (22%)
Query: 703 AMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVP------ 756
A + P P P PG P +PPP P L +VL V +P+
Sbjct: 12 AAARTPAARAPGLLTPRPPGSP-----RPPPPVTPAAL-RVLGAAGAVGRKPLAERAGGI 65
Query: 757 -----PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPP-------- 803
P P P G ++ + P + A P PV P
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 804 ITPLAGIDGLPPALPDLPT---ATVPPV--------------PPPQYFSPAVILPSLAA- 845
PL G GL + + AT P P P SPA+ S AA
Sbjct: 126 PGPL-GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 846 -------PLPPASPALPLQAVKL------------PHP-----PGA-------------- 867
P P A P P + + P P P A
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 868 ---PLAMPCRT-----------IVPNAPATIPLLAVAPPGVAALSIHSAVAQLP------ 907
PL+ P R+ P+ P L A+ PP V +A A P
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 908 GQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQ-PVLPPQPTLPP-- 964
P AA AP +P +PH + + P P PP P+ PP LP P PP
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364
Query: 965 ------QPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT 1018
P L Q T P P P+ P P PP ALP P P +P AT
Sbjct: 365 ATTSLGSPTL--QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 422
Query: 1019 PGSQILLGHPAPYAVDV-AAQVPTVPVPPAAVLSPPLPEVLLPAAPELLP--QFPSSLAT 1075
P Q AP A+ V Q P P P V +P P P +P P Q P SLA
Sbjct: 423 PSPQ------APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
Query: 1076 VSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKP-PGLPQS 1134
V P + + P A PP P +A+ P +QL P Q A P LP
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLAA--PPLQLAKPPPQAPPALATPPLQALPSP 534
Query: 1135 CESYGG 1140
S+ G
Sbjct: 535 PASFPG 540
Score = 77.0 bits (188), Expect = 2e-13
Identities = 114/433 (26%), Positives = 151/433 (34%), Gaps = 88/433 (20%)
Query: 1323 APEAPESSPPLPLSSL-PPEAS---QDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPG 1378
AP P P L +L PP+ + +D+AP LSS + S L SQA P+ P
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPAT 324
Query: 1379 ----------APPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTS 1428
A P PLAP SP A P+ T+P P + SQA T G +
Sbjct: 325 PHSSSLTCQLATPLPLAPPSP--------SAPPSLQTLPSPPATPPSQAT---TSLGSPT 373
Query: 1429 ELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEP------ 1482
T L +PLA P A P +A + AS P PL P+P+
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433
Query: 1483 ----SPHSGTPQPALGQP------APLLPAAV----GAVSLATSQLPSPPLGPTVPPQPP 1528
+P S P P + P P+ P+A SLA L PP P PP P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Query: 1529 SALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPL 1588
SA + PPP K + L S A P G F+
Sbjct: 494 SATPPP-QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP---GQAPFS---- 545
Query: 1589 RGDQPRSEVCGGDLALPP--VPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTA 1646
P + + LA PP P + +Q+P +PT A T T+
Sbjct: 546 ----PSASLPMSPLATPPPQAPPVLAAPLLQVP----PSPPASPTLQAPRRPPTPGPDTS 597
Query: 1647 ESSPRSMLGY--------------DRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRD 1692
S PR L G +A S S P+++ + D
Sbjct: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY-----------D 646
Query: 1693 GGEAGESSAEPPP 1705
G G ++A PPP
Sbjct: 647 SGPEGGAAASPPP 659
Score = 61.2 bits (147), Expect = 1e-08
Identities = 143/590 (24%), Positives = 191/590 (32%), Gaps = 146/590 (24%)
Query: 1317 PVAEHPAPEAPESSP--------PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLL 1368
P A++ +P P SSP P PL S + + + + + S L++
Sbjct: 104 PPAKNTSP-GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162
Query: 1369 SQAGPSNPPGAP-------------------PAPLAPSSPPVTALPQDGAAPAT---STM 1406
+GP+ PG P PAP A PP T P+ + A+ +T
Sbjct: 163 DTSGPT--PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-TEGPRKSVSSASEHSTTE 219
Query: 1407 PEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTR 1466
P PA+ AGG S ++ PL+ +P P G P +
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLS----SPARSGPSARGTPRAPAHPSQPKPK 275
Query: 1467 DASAPREP-LPPPAPEPSPHSG--------TPQPALG---QPAPLLPAAVGAVSLATSQL 1514
A R P + PP + +P G TP P+ Q P LPA + SL T QL
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL-TCQL 334
Query: 1515 PSP-PLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSA--S 1571
+P PL P P PPS L+TL P S A S
Sbjct: 335 ATPLPLAPPSPSAPPS--------------------------LQTLPSPPATPPSQATTS 368
Query: 1572 AGTPVEVGDRDFT----LEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSE 1627
G+P F L PL P++ LALPP+ PL S
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPA---LALPPLQAPPSPPASPPLSPLATPSP 425
Query: 1628 LAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVE 1687
AP AV + + SP + S S PS Q P+ P
Sbjct: 426 QAPNALAV--HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS--QAPPSLAAPPLQV 481
Query: 1688 PTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGR 1747
P SA PPP P L A L + P+ + PA
Sbjct: 482 PPSPPASPPMSPSATPPPQA----------PPPLAAPPLQLAKPPPQ----APPA----- 522
Query: 1748 FSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSS 1807
LA+P +PP + +AP SP L + T
Sbjct: 523 -----------LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP------------- 558
Query: 1808 DSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET 1857
P PPV L V S A+ LQ P R + GP+T
Sbjct: 559 ------PPQAPPVLAAPLLQVPPS------PPASPTLQAPRRPPTPGPDT 596
Score = 53.9 bits (128), Expect = 2e-06
Identities = 122/503 (24%), Positives = 162/503 (32%), Gaps = 125/503 (24%)
Query: 1370 QAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG----GPGTPQG 1425
+AGP+ G + P+S P + + A PA +T P P S +G GP +G
Sbjct: 76 RAGPTRSAGT--SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 1426 LTSELETSQPLAETHEAP------LAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA 1479
L E + + EAP + G P TP+P A A+ LP PA
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
Query: 1480 PEPSPHSGTPQP----------ALGQPAPLL---PAAVGAV------SLATSQLP--SP- 1517
P P T P + +P+P P+A G + SL++S P SP
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 1518 ---------PLGPTVPPQP-PSALES--DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV 1565
P P P QP P L++ + PPR +
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL----------------G 297
Query: 1566 PTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLA-----LPPVPKEAVSGRVQLPQ 1620
P SS+ TP P P S LA PP P S +
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357
Query: 1621 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1680
P S+ + G+ Q T S + S P S L PQ PA
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFL--PSPPLSPL---------------ATPPPQAPPAL 400
Query: 1681 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1740
P P A PP S + T QA P L L +P P V +
Sbjct: 401 ALPPLQAPP--------SPPASPPLSPLATPSPQA--PNALAVHLLQAPFSPPPSPPVQA 450
Query: 1741 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVY---LDEAPSSPDVKLAVRRAQTASSI 1797
P FS ++ A+P S APP + L PS P
Sbjct: 451 P------FSPPASPPVSPSATPPS---QAPPSLAAPPLQVPPSPP--------------- 486
Query: 1798 EVGVGEPVSSDSGDEGPRARPPV 1820
P S S P+A PP+
Sbjct: 487 ----ASPPMSPSATPPPQAPPPL 505
Score = 53.1 bits (126), Expect = 3e-06
Identities = 72/245 (29%), Positives = 95/245 (38%), Gaps = 39/245 (15%)
Query: 1322 PAPEAPE--SSPPLPLSSLPPEASQDSA-PYKDQLSSKE-----QPSFLASQQLLSQAGP 1373
P P+AP ++PPL L+ PP+A A P L S Q F S L
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
Query: 1374 SNPPGAPP---APL--APSSPPVTALPQDGAAPATSTMPEPASG---TASQAGGPGTPQG 1425
+ PP APP APL P SPP + Q P T SG T + A GP P
Sbjct: 557 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 616
Query: 1426 LTSELETSQPLAETHEAPLAVQPLVV--------GLAPCTPAPEA--ASTRDASAPREPL 1475
+ S P H + P + G A +P P+A A+ A+ R P
Sbjct: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 676
Query: 1476 PPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDG 1535
PP A +P + P P PA +A G ++ ++ GP P AL+
Sbjct: 677 PPLAFRGAPGAPLPWP----PATGPGSADGLCTIYETE------GPESATPAPGALD--- 723
Query: 1536 EGPPP 1540
GP P
Sbjct: 724 PGPSP 728
Score = 46.6 bits (109), Expect = 3e-04
Identities = 109/459 (23%), Positives = 158/459 (34%), Gaps = 85/459 (18%)
Query: 1452 GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLAT 1511
G A TPA A P P PPP P+ PL A G + AT
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA-GGIGGAT 69
Query: 1512 SQLPSPPLGPT---------VPPQPPSA--------LESDGEGPPPRVGFVDSTIK--SL 1552
+P GPT +PP++ ++ GP G T + L
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 1553 DEKLRTLLYQEHVPTSSASAG---TPVEVGDRDFTLEPLRGDQP-----RSEVCGGDLAL 1604
+K + +E V A+ + + G R T P G RS G ++ L
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 1605 P-PVPKEAVSGRVQLPQPLV---------EKSELA---PTRGAVMEQGTSSSMTAESSPR 1651
P P P + P+ V E S A P+ G +++ S S+++ ++P
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 1652 SMLGYDRDGRQVASDSHVVPSVPQDVP-AFVRPARVEPTDRDGGEA-GESSAEPPPSDMG 1709
S + + PS P+ +RP +V P +D A G S+ P +
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
Query: 1710 TVGGQASHPQTLGAR----------------ALGSPRKRPEQQDVSSPAKTVGRFSVVST 1753
+ Q+ P TL A A SP P Q + SP T + S
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
Query: 1754 QDEWTLASPHSLRYS------------APPDVYLD--EAPSSPDVK-----LAVRRAQTA 1794
TL + HS S APP + L +AP SP LA Q
Sbjct: 370 GSP-TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428
Query: 1795 SSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVA 1833
+++ V + + S P PPVQ S P S V+
Sbjct: 429 NALAVHLLQAPFS------PPPSPPVQAPFSPPASPPVS 461
Score = 46.6 bits (109), Expect = 3e-04
Identities = 69/237 (29%), Positives = 89/237 (37%), Gaps = 46/237 (19%)
Query: 1322 PAPEAPES--SPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQL-------LSQAG 1372
P P+AP + +PPL PP + AP+ S P Q L Q
Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574
Query: 1373 PSNPPGAPP--APLAPSSP-PVTAL--PQDGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427
PS PP +P AP P +P P T++ P+ A A P P+ +S GP +
Sbjct: 575 PS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 633
Query: 1428 SELETSQPLAETHEAP----LAVQPLVVGLAPCTPAP----EAASTRDASAPREPLP-PP 1478
S T + L P A P LA C PA A AP PLP PP
Sbjct: 634 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 693
Query: 1479 A-----------------PE---PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLP 1515
A PE P+P + P P+ G AA GA + A+S+ P
Sbjct: 694 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAGAGASSRSP 748
Score = 38.9 bits (89), Expect = 0.057
Identities = 40/157 (25%), Positives = 58/157 (36%), Gaps = 25/157 (15%)
Query: 11 PGTLMEPGRGAG---PAGM-----AEPRAKAARPGPQ-RFLRRSVVESDQEEPPGLEAAE 61
P P G G PA A P + AR GP R R+ Q +P GL+A
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 62 APGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGT 121
P PP+ L + L A P+P+A + P PA +
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPL---------ATPSPSAALQSQAPPTLPATPHSSSLTC 332
Query: 122 QEPGPDPIA-------AAVETAPAPDGGPREEAAATV 151
Q P P+A +++T P+P P +A ++
Sbjct: 333 QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
Score = 37.0 bits (84), Expect = 0.22
Identities = 40/154 (25%), Positives = 57/154 (37%), Gaps = 10/154 (6%)
Query: 14 LMEPGRGAGPAGMAEPRAKA--ARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPL 71
L P R +GP+ PRA A ++P P+ + Q PP +AA A GP PL
Sbjct: 249 LSSPAR-SGPSARGTPRAPAHPSQPKPKGL---QALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 72 QRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAA 131
+ L ++ PA P ++L Q P A P + + P P A
Sbjct: 305 ATP----SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
Query: 132 AVETAPAPDGGPREEAAATVRKEDEGAAEAKPEP 165
A G P +A + + A P P
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394
Score = 36.6 bits (83), Expect = 0.28
Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 4/97 (4%)
Query: 55 PGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPG-APGAPAD 113
P + + P PQ P PL L L K P P+ + PG AP +P+
Sbjct: 489 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
Query: 114 AGP-EPVGTQEPGPDPIAAA--VETAPAPDGGPREEA 147
+ P P+ T P P+ AA ++ P+P P +A
Sbjct: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
Score = 32.3 bits (72), Expect = 5.3
Identities = 44/166 (26%), Positives = 51/166 (30%), Gaps = 18/166 (10%)
Query: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQP 70
P L P P+ A P +A R P SV P L A APGP PP
Sbjct: 563 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV------SGPRLTLALAPGPPPPPS 616
Query: 71 LQRRVLLL-------CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQE 123
L + E RG + P A + P P A A ++
Sbjct: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP--PDAELAACHPAAWSRG 674
Query: 124 PGPDPIAAAVETAP---APDGGPREEAAATVRKEDEGAAEAKPEPG 166
P P AP P GP E EG A P PG
Sbjct: 675 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 720
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 136 bits (342), Expect = 3e-31
Identities = 145/508 (28%), Positives = 183/508 (36%), Gaps = 60/508 (11%)
Query: 643 AAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702
A P+P Q S P ++ P+ + G P P A PPS + P
Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGGPATP 957
Query: 703 AMSFAPVLPPPSTPMPT-GPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPP 761
+ +AP P + P P GP P+P G PP A P P P+ P P P PP
Sbjct: 958 SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP-PSPK---GGPATP-SPKGAPTPP 1012
Query: 762 YLAPASQVGAPAQL---KPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLP--PA 816
+ P S G+PA K P A P + P P+P P TP A + PA
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA 1072
Query: 817 LPDLPTATVPP--VPPPQYFSPAVILPSLAAPLPP-ASPALPLQAVKLPHPPGAP----- 868
P L A PP PP PA P AP+PP A+P P + P GAP
Sbjct: 1073 TPSLKGAPTPPAATPPSPKGGPATPSPK-GAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131
Query: 869 --------LAMPCRTIVPNAPATIPL-----LAVAPPGVAALSIHS---------AVAQL 906
LA P P PA P LA PP A + + A
Sbjct: 1132 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSP 1191
Query: 907 PGQPVYPAAFPQMAPTDV-PPSPHHTVQNMRATPPQP----ALPPQPTLPPQPVLPPQPT 961
G P PAA P + PSP ATPP P A P P P P P+
Sbjct: 1192 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP-PS 1250
Query: 962 LPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGS 1021
P PP P P P P L PP P P + P P + PA +P
Sbjct: 1251 PKGGPATPPPKGAPTPPAATP-PSLKGGLATPPHKGAP-NPAVVTPPSP-KGGPATSPPK 1307
Query: 1022 QILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQ 1081
G P P A + + PP P P + P +P+ P P++ +
Sbjct: 1308 ----GAPTPPAATPPSPKGSPGTPPPK--GAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 1082 SVPTQTATLLPPANPPLPGGPGIASPCP 1109
+ ++ P A P GGP + P P
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSP 1389
Score = 120 bits (302), Expect = 1e-26
Identities = 169/699 (24%), Positives = 224/699 (32%), Gaps = 154/699 (22%)
Query: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSA 607
P+L+ +P +G P + G P PP P L P +
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPAT-------PSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126
Query: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLP 667
T+ A+ T S +G + + + A PSP + +PP P P + P
Sbjct: 1127 TTPAA--TPPSPKGGLATPPPKGAPTTP-----AATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 668 SL-----------GAYQQPTAAPGLPVGSVPAP----------ACPPSLQQHFPDPAMSF 706
GA P A P P G + P A PPS + P+
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239
Query: 707 APVLPPPSTPMPTG-PGQPAPPGQQPPPLAQPTPL-------PQVLAPQPVVPLQPVPPH 758
AP P + P P G P P P G PP A P L P AP P V P P
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299
Query: 759 -----------LPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPL 807
PP P S G+P P P P A PP P +P TP
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP----AVTPPSPKGTPTLPATTPS 1355
Query: 808 AGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHP--- 864
+ P+ + PT PP P + P++ P P PA+P P
Sbjct: 1356 SKGGPTTPSSKEGPT---PPAATPSHKGG----PAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVA-----------QLPGQPVYP 913
P +P P + AT + PP V +S+ A A G P P
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468
Query: 914 AAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP---------------------- 951
A P P T + + P PA PTLP
Sbjct: 1469 AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIA 1528
Query: 952 ----------PQPVLPPQPTLPPQPVLP-PQPTRPPQPVLPPQPMLPPQPVLPPQPALPV 1000
P + P + +PP +P P+ T P P PA P
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKT-------------PAIPTPKEAPATPS 1575
Query: 1001 RPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPT---VPVPPAAVLSPPLPE- 1056
E P PA TP + P + A P+ P PPA ++PP PE
Sbjct: 1576 SKEASSP-------PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA--VTPPSPEK 1626
Query: 1057 -VLLPA---APELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPG-------IA 1105
PA P P PSSL S SV + +P A+ LP G +
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLV 1686
Query: 1106 SPCP-TVQLTVEPV----QEEQASQDKPPGLPQSCESYG 1139
+P P + + P Q +++S PP P G
Sbjct: 1687 APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNG 1725
Score = 119 bits (297), Expect = 4e-26
Identities = 172/668 (25%), Positives = 231/668 (34%), Gaps = 100/668 (14%)
Query: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSA 607
PA P + + +G P P T + G P P P+ + PP+ S
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTP--PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPS-PAQCVCSP------------ 654
+ + F G + + S + S L AP+ PA + SP
Sbjct: 1024 AA----TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 655 --PVSEGPVLPQSLPSL----GAYQQPTAAPGLPVGSVPAP----------ACPPSLQQH 698
P + P P+ P+ GA P A P P G + P A PPS
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS---- 1135
Query: 699 FPDPAMSFAPVLPPPSTPMPTGP------GQPAPPGQQPPPLA-QPTPLPQVLAPQPV-V 750
P ++ P P+TP T P P P G P A P+P + P P
Sbjct: 1136 -PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA 1194
Query: 751 PLQP--VPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ-MPPIPVVPPITPL 807
P P PP LA S GAP P P +P LA P+ P P P +P
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPT--TPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252
Query: 808 AGIDGLPPALPDLPTATVPP-------------------VPPPQYFSPAVILPSLAAPLP 848
G PP P A PP V PP P AP P
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312
Query: 849 P-ASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLP 907
P A+P P + P P GAP P P+ T L A P + S+
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAP--TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS----K 1366
Query: 908 GQPVYPAAFP--QMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQ 965
P PAA P + P PPSP + P P+ PT P L P+ P
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSP-------KRGPAIPSPKGDPTSPAVIPLSPKKA-PAT 1418
Query: 966 PVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILL 1025
PV P + L P + P P + P + PA TP S
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSP--K 1476
Query: 1026 GHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLA-TVSASVQSVP 1084
PAP V ++ P PA + +P LP V +P++P+ +P PSS ++ + +
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPAV-IPSSPKEVPATPSSRRDPIAPTATLLS 1535
Query: 1085 TQTATLLPPANPPLPGGPGIASPCPTVQLTV---EPVQEEQASQDKPPGLPQSCESYGGS 1141
+T L P +P + SP T + P PP + S +Y G+
Sbjct: 1536 KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS--TYKGA 1593
Query: 1142 DVTSGKEL 1149
S KEL
Sbjct: 1594 --PSPKEL 1599
Score = 114 bits (285), Expect = 1e-24
Identities = 175/694 (25%), Positives = 244/694 (35%), Gaps = 110/694 (15%)
Query: 564 ARGPP--VPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPP------TLP-TSATSLASDS 614
A PP P T + G PG P P+ + PP TLP T+ +S +
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 615 TFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQ 674
T S +G T + + S + G A PSP + P P P +P
Sbjct: 1362 TPSSKEGPTPPAATPSHK-----GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL-----S 1411
Query: 675 PTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPL 734
P AP PV A PS P PA++ + P+T P G PA P + P
Sbjct: 1412 PKKAPATPV--TREGAATPSKGDLTP-PAVTPVSLKKAPATSAPKGG--PATPSSKGDPT 1466
Query: 735 AQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ 794
LP V P P P P P + +P APA P+ P +P
Sbjct: 1467 -----LPAVTPPSPKEP--PAPKQVATSSSPKK---APATPAPMGAPT--------LPAV 1508
Query: 795 MPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSP--AVILPSLAAPLPPASP 852
+P P P TP + D P PTAT+ P +P A+I P++ P P +P
Sbjct: 1509 IPSSPKEVPATPSSRRD------PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP 1562
Query: 853 ALPLQAVKLPHPPGAPLAMPCRTIVPNA--PATIPLLAVAPPGVAALSIHSAVAQLPGQP 910
A+P + P P + A + P+ A P + PP V + S A P
Sbjct: 1563 AIPTPK-EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621
Query: 911 VYPAAFPQM-APTDVPPSPHHTVQNMRATPPQPA----------------LPPQ--PTLP 951
P P AP P SP T +++ +P PA LP + PT
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681
Query: 952 PQPVLPPQPTLPPQPVLP----PQPTRPP--QPVLPPQPMLP-----PQPVLPPQPALPV 1000
+ ++ P P P P PQ + P + P P P + P P LPV
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV 1741
Query: 1001 RPE----------------PLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044
+ + PL P + + P + +L P +A V P
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPE------SASVSAAPS 1795
Query: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANP-PLPGG-- 1101
PP ++ P P LP + LP P L S S P LLP P P+ GG
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQQFLPSSP-GLVLESPSKPLAPADEDELLPLIPPEPISGGVP 1854
Query: 1102 -PGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGG 1160
+ PT + PV A Q S + E DS +
Sbjct: 1855 FQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQA 1914
Query: 1161 RLEGRAARKHHRRSTRARSRQERASRPRLTILNV 1194
+L A S +SR E+ +R ++ L +
Sbjct: 1915 QLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGL 1948
Score = 102 bits (254), Expect = 4e-21
Identities = 160/629 (25%), Positives = 217/629 (34%), Gaps = 80/629 (12%)
Query: 546 IWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPT 605
+ P +Q + + P +PL + T ++ G P P A P + +
Sbjct: 559 VLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKS--LGEPLPIGKPASSMTSPLGVNS 616
Query: 606 SATSLASDSTFDSGQGSTVYSDSQSSQQSVML----GSLADAAPSPAQCVCSPPVSEGPV 661
SA+ + +DS + S + A AP+ A+ + + P
Sbjct: 617 SASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF 676
Query: 662 LPQSLPSLGAYQQP------TAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPST 715
L ++ SL P T P +P S P P P + AP +P S
Sbjct: 677 LEGTV-SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPK-SV 734
Query: 716 PMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQL 775
P P+ P PPG + T LAP P + P A AS G L
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHT---SALAPVASSPKE-CPTEDSGASATASSKGTLTYL 790
Query: 776 KPLQMPQA-PLQPLAQVPPQM-----PPIPVVPPITPLAGIDG--LPP------ALPDLP 821
P + P + PP P P+ +P++ ++ LP D P
Sbjct: 791 ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP 850
Query: 822 TATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAP 881
T P PP +P PS PL P LP + + P P L P AP
Sbjct: 851 ATTHSPTPPSPKGAPT---PSAVTPLSPKGVTLPPK--ETPTPSVVNLPFPKEGPATPAP 905
Query: 882 ATIPLLAV---APPGVAALSIHSAVAQLP---GQPVYPAAFPQMAPTDVP--PSPHHTVQ 933
P L++ +P A + P G P PAA P +P P PSP
Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP-SPKGGPATPSPKWAPT 964
Query: 934 NMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
ATPP P P P PP T PP P P P PP V P
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAAT-------PPSPKGGPATPSPKGAPTPP-AVTP 1016
Query: 994 PQPALPVRPEPLQPHLPEQAA--PAATPGSQILLGHPAPYAVDVAAQVPT-VPVPPAAVL 1050
P P + P P+ A+ PAATP P+P A +P P PAA L
Sbjct: 1017 PSP----KGSPAATPFPKGASTPPAATP--------PSPKGSPAATPLPKGAPTTPAATL 1064
Query: 1051 SPPLPEVLLPAAPEL--LPQFPSSLATVSASVQSVPTQTATLLPP-ANPPLPGGPGIASP 1107
P PA P L P P++ + P+ +PP A PP P G G+A+P
Sbjct: 1065 PSPKGG---PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG-GLATP 1120
Query: 1108 ----CPTVQLTVEPVQEEQASQDKPPGLP 1132
PT P + + P G P
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAP 1149
Score = 90.5 bits (223), Expect = 2e-17
Identities = 142/588 (24%), Positives = 201/588 (34%), Gaps = 78/588 (13%)
Query: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGA 1379
E PA AP+ +P L ++S P+ ++ + P + + P + + P P
Sbjct: 898 EGPATPAPKQAPALSMTSSSPKKAR-ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
Query: 1380 PPAPLAPSSPPVTALPQDG--AAPATSTMPEPASGTA-SQAGGPGTPQGLTSELETSQPL 1436
P AP+ P T G A P+ P P + T S GGP TP S
Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP---------SPKG 1007
Query: 1437 AETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQP 1496
A T P P G TP P+ AST A+ P P PA P P PA P
Sbjct: 1008 APT--PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065
Query: 1497 A----PLLPAAVGAVSLATSQLPSPPLGPTVP-----PQPPSALESDGEG---PPPRVGF 1544
+ P P+ GA + + PSP GP P P PP+A +G PP G
Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125
Query: 1545 VDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLAL 1604
+ + L + A TP T P + A
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA-------AT 1178
Query: 1605 PPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVA 1664
PP PK ++ P + +G + T S A ++P + + G
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGL---ATPSPKGAPTTPAATPPSPKGGLATP 1235
Query: 1665 SDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGAR 1724
S P+ P PA P+ + G A PPP G A+ P +L
Sbjct: 1236 S--------PKGAP--TTPAATPPSPKGG------PATPPPK--GAPTPPAATPPSLKGG 1277
Query: 1725 ALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWT--LASPHSLRYS----------APPD 1772
P K V +P G + + T A+P S + S PP
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337
Query: 1773 VYLDE---APSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVS 1829
V P+ P + + T S + G P ++ S GP PP K+ P
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG--PAI 1395
Query: 1830 GSVAGDFVKKATAFLQRPSRAGSL-----GPETPSRVGMKVPTISVTS 1872
S GD A L P +A + G TPS+ + P ++ S
Sbjct: 1396 PSPKGDPTSPAVIPLS-PKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Score = 82.8 bits (203), Expect = 3e-15
Identities = 218/940 (23%), Positives = 316/940 (33%), Gaps = 180/940 (19%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSS---KEQPSFLASQQLLSQAGP 1373
P P+P+ ++ P P + P A+ +P ++ K P+ A+ + GP
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071
Query: 1374 SNPP--GAPPAPLA-PSSP---PVTALPQDGAAPATSTMPEPASGTAS--QAGGPGTPQG 1425
+ P GAP P A P SP P T P+ P +T P P G A+ G P TP
Sbjct: 1072 ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131
Query: 1426 LTSELE---TSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREP---LPPPA 1479
+ + P P A P G TP P+ A T A+ P P L P+
Sbjct: 1132 TPPSPKGGLATPPPKGAPTTPAATPPSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 1480 PE----------PSPHSG--TPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQP 1527
P+ PSP G TP P + AP PAA PSP PT P
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSP---KGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1247
Query: 1528 PSALESDGEGPPPRVGFVD--STIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTL 1585
P + + PPP+ +T SL L T H + + TP T
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT---PPHKGAPNPAVVTPPSPKGGPATS 1304
Query: 1586 EPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMT 1645
P P + A PP PK G P P + APT AV
Sbjct: 1305 PPKGAPTPPA-------ATPPSPK----GSPGTPPP-----KGAPTPPAV---------- 1338
Query: 1646 AESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAE--- 1702
+P S G P++P P+ GG SS E
Sbjct: 1339 ---TPPSPKG--------------TPTLPATTPS-----------SKGGPTTPSSKEGPT 1370
Query: 1703 PPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASP 1762
PP + GG A P SP++ P + SP +V+ + A+P
Sbjct: 1371 PPAATPSHKGGPAMTPP--------SPKRGPA---IPSPKGDPTSPAVIPLSPKKAPATP 1419
Query: 1763 HSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQK 1822
+ +A P P+ V L ++A S+ + G P SS P PP K
Sbjct: 1420 VTREGAATPSKGDLTPPAVTPVSL--KKAPATSAPKGGPATP-SSKGDPTLPAVTPPSPK 1476
Query: 1823 QASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGM-KVPTISVTSFHSQSSYIS 1881
+ P K A P +A P TP+ +G +P + +S + S
Sbjct: 1477 EPPAP-----------KQVATSSSPKKA----PATPAPMGAPTLPAVIPSSPKEVPATPS 1521
Query: 1882 SDNDSELEDADI--KKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNVGFFHT 1939
S D A + KK +L K + ++ A+ P P
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI------PTPKEA----P 1571
Query: 1940 APPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADSSRGPPAKDPAQASVGLTAD 1999
A P+ + + + + P ++L + + T + PPA P G
Sbjct: 1572 ATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP 1631
Query: 2000 STGLSGKAVQTQQPCSVRASLSSDICSGLASDGGGARGQGWTVYHPTSERVTYKSSSKPR 2059
+ K T P + S + S G TV + K + +
Sbjct: 1632 AP----KGTPTSPPVT-----PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALK 1682
Query: 2060 ARFLS-GPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPGPQPALHVQAQVNNSNNKK 2118
++ P S I +A R G + S+TS P P P+ N K
Sbjct: 1683 EVLVAPAPESTPIITAPTR--KGPQTKKSSATS-----PPICPDPSA--------KNGSK 1727
Query: 2119 GTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQD-MEAQAGWAAPGEARAMTAPR 2177
G + TV A L P +T K +D + G AP E++A T P
Sbjct: 1728 GPLS-------------TVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST-PL 1773
Query: 2178 AGVGMPRLPPAPGPLSTTVIPGAAPTLSVP-TPDPESEKP 2216
++ P P S + P +P +S+P P P P
Sbjct: 1774 TAAAFEKVLPKPESASVSAAP--SPPVSLPLAPSPVPTLP 1811
Score = 81.3 bits (199), Expect = 1e-14
Identities = 150/633 (23%), Positives = 222/633 (35%), Gaps = 99/633 (15%)
Query: 1323 APEAPESSPPLPLSS--LPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP---- 1376
AP P ++PP P S PP + P S K P+ A+ S+ GP+ P
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS-SKGGPTTPSSKE 1367
Query: 1377 -PGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQP 1435
P P A + P P PA +P P S A P +P+ + T +
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSPKRGPA---IPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424
Query: 1436 LAETHEA---PLAVQPLVVGLAPCTPAPEAAS---------TRDASAPREPLPPPAPEPS 1483
A + P AV P+ + AP T AP+ T A P P PPAP+
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 1484 PHSGTPQPALGQPAPL----LPAAVGAVSLATSQLPS---PPLGPT---VPPQPPSALES 1533
S +P+ A PAP+ LPA + + PS P+ PT + + P+ L
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP 1544
Query: 1534 DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPT--SSASAGTPVEVGDRDFTLEPLRGD 1591
PP + T+ S +K + + P SS A +P V T +G
Sbjct: 1545 KEALIPPAM-----TVPS-PKKTPAIPTPKEAPATPSSKEASSPPAV-----TPSTYKGA 1593
Query: 1592 QPRSEVCGGDLALPPVPKEAVSGRVQLPQ-----PLVEKSELAPTRGAVMEQGTSSSMTA 1646
E+ P PKEA + P P + PT V S T+
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS 1653
Query: 1647 ESS---------PRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAG 1697
+S P++ G A +V P+ P P R P +
Sbjct: 1654 PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATS 1713
Query: 1698 ESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVS-------SPAKTVGRFSV 1750
P + G+ G ++ K + +D S +P ++ +
Sbjct: 1714 PPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPL 1773
Query: 1751 VSTQDEWTLASPHSLRYSAPPD--VYLDEAPSSPDVKLAVRRAQTASS---IEVGVGEPV 1805
+ E L P S SA P V L AP SP L ++ SS + +P+
Sbjct: 1774 TAAAFEKVLPKPESASVSAAPSPPVSLPLAP-SPVPTLPPKQQFLPSSPGLVLESPSKPL 1832
Query: 1806 SSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKV 1865
+ DE PP P+SG V P ++ + TP G+ V
Sbjct: 1833 APADEDELLPLIPPE------PISGGV--------------PFQSVLVNMPTPKSAGIPV 1872
Query: 1866 PTISV---TSFHSQSSYISSDNDS---ELEDAD 1892
PT S + +++ S SD+D ELE+ D
Sbjct: 1873 PTPSAKQPVTKNNKGSGTESDSDESVPELEEQD 1905
Score = 67.8 bits (164), Expect = 1e-10
Identities = 153/637 (24%), Positives = 228/637 (35%), Gaps = 121/637 (18%)
Query: 552 PKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGP--PEPEEPEADQHLLPPTLPTSATS 609
P +Q++ P +A +P+ ++ A GQPGP P P P Q P + A+
Sbjct: 10 PATEQELPQP-QAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQ--CPLSAANQASP 66
Query: 610 LASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEG------PVLP 663
S ST S + S SS ++ LG+ A AP+ + PP+S P++
Sbjct: 67 FPSPSTIASTPLEVPFPQS-SSGTALPLGT-APEAPTFLPNLIGPPISPAALALASPMIA 124
Query: 664 QSLPSLGAYQQPTAAPGLPVGSVP-APACPPSLQQHFPDPAMS--------FAPVLPP-- 712
+L + P A L SV + A PP+L P A++ AP+ P
Sbjct: 125 PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEP 184
Query: 713 -------PSTPMPTGPGQPAPP-------------------GQQPPPLAQPTPLPQVLAP 746
PS +P G P+PP G P PT + +P
Sbjct: 185 KTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244
Query: 747 Q---PVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQ------VPPQMPP 797
Q + + P P L+ V PA L L P+ +Q PP P
Sbjct: 245 QVKDTTISSVLISPQNPGSLSLKGPVSPPAALS-LSTQSLPVVTSSQKTAGPNTPPDFP- 302
Query: 798 IPVVPPITPL----------AGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPL 847
I + + PL G G P AL D T+ + S PS + +
Sbjct: 303 ISLGSHLAPLHQSSFGSVQLLGQTG-PSALSDPTVKTISV----DHSSTGASYPSQRSVI 357
Query: 848 PPASPALPLQAVKLPHPPGA-PLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQ- 905
PP LP + +P A P+ P V P+TI + +P G ++ +++
Sbjct: 358 PP----LPSRNEVVPATVAAFPVVAPS---VDKGPSTISSITCSPSGSLNVATSFSLSPT 410
Query: 906 ----LPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTL-------PPQ- 953
L P +P +A +P S T + P A P T PP
Sbjct: 411 TSLILKSSPNATYHYPLVA--QMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMS 468
Query: 954 --PVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPE 1011
P+ +PT P V+ P + P + +P P LP L P + P
Sbjct: 469 SGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPT 528
Query: 1012 QAAPAATPGSQILLGHP-APYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFP 1070
Q P S L G P +P + + +P L+ AAP+ P F
Sbjct: 529 QKDLQTVPAS--LEGAPFSPAQAGLTTKKDPTVLP------------LVQAAPKNSPSFQ 574
Query: 1071 SSLATVSASVQSVPTQTATLLPPA-NPPLPGGPGIAS 1106
S+ S+S + + ATL + PLP G +S
Sbjct: 575 ST----SSSPEIPLSPEATLAKKSLGEPLPIGKPASS 607
Score = 65.5 bits (158), Expect = 6e-10
Identities = 101/385 (26%), Positives = 145/385 (37%), Gaps = 63/385 (16%)
Query: 524 DVKIVAKSIRDRVALIQWRRERIWPA-LQPKEQ-----QDVGSPDKARGPPVPLQVQVTY 577
+V S RD +A + PA L PKE V SP K P P + T
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574
Query: 578 HA-QAGQPGPPEPEE----PEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQ 632
+ +A P P P + L+PP ++ S S ++ V S
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPP-------AVTSPSPKEAPTPPAVTPPSPEK- 1626
Query: 633 QSVMLGSLADAAPSPAQCVCSPPVS-----EGPVLPQSLPSLGAYQQPTAAPGLPVGSVP 687
A P+P SPPV+ + P P S+ P A+ GLP
Sbjct: 1627 --------GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP----- 1673
Query: 688 APACPPSLQQHFPDPAMSFAPVLPPPSTPMP-TGPGQPAPPGQQPPPLAQ---PTPLPQV 743
A P +L++ PA P++ P+ P T P P P A+ PL V
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTV 1733
Query: 744 LAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPP 803
AP P++P+Q + + G A P + P AP + A P V P
Sbjct: 1734 -APAPLLPVQKD--------SSKTAKGKDASHSP-KGPLAPPESKASTPLTAAAFEKVLP 1783
Query: 804 ITPLAGIDGLPPALPDLPTAT--VPPVPPPQYF---SPAVILPSLAAPLPPASPALPLQA 858
A + P LP A VP +PP Q F SP ++L S + PL PA +
Sbjct: 1784 KPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPAD-----ED 1838
Query: 859 VKLPHPPGAPLA--MPCRTIVPNAP 881
LP P P++ +P ++++ N P
Sbjct: 1839 ELLPLIPPEPISGGVPFQSVLVNMP 1863
Score = 62.4 bits (150), Expect = 5e-09
Identities = 92/366 (25%), Positives = 124/366 (33%), Gaps = 45/366 (12%)
Query: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSA 607
PA+ P ++V + +R P+ + P E P A P P
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP 1565
Query: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQ-----CVCSPPVSEGPVL 662
T + +T S ++S + S APSP + V SP E P
Sbjct: 1566 TPKEAPAT---------PSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
Query: 663 PQSLPSLGAYQQPTAAP-GLPVGSVPAPACPPSLQQHFPDPAM---SFAPVLPPPSTPMP 718
P P T AP G P P P SL+ PA +P S +P
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSP---PVTPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673
Query: 719 TGPGQPAPPGQQPPPLAQPTPL---PQVLAPQPVVPLQPVPPHLPPYLAPASQVG----- 770
G A P + TP+ P PQ PP P A G
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTV 1733
Query: 771 APAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPP----ITPLAGIDGLPPALPDLPTATVP 826
APA L P+Q + + P P+ PP TPL LP +A+V
Sbjct: 1734 APAPLLPVQKDSSKTAK-GKDASHSPKGPLAPPESKASTPLTAA-AFEKVLPKPESASVS 1791
Query: 827 PVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVP-NAPATIP 885
P SP V LP +P+P LP + LP PG L P + + P + +P
Sbjct: 1792 AAP-----SPPVSLPLAPSPVP----TLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842
Query: 886 LLAVAP 891
L+ P
Sbjct: 1843 LIPPEP 1848
Score = 58.2 bits (139), Expect = 9e-08
Identities = 133/569 (23%), Positives = 192/569 (33%), Gaps = 93/569 (16%)
Query: 1322 PAPEAPESSPPLPLS---SLPPEASQDSAPYKDQLSSKEQPSFLASQQLL----SQAGPS 1374
P+ ++ SSP +PLS +L ++ + P SS P + S + S AGP
Sbjct: 571 PSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPD 630
Query: 1375 NPPGAPPAPLAPSS---PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTP--QGLTSE 1429
+ PL SS P V A P + A PA P A GT++ +P +G S
Sbjct: 631 SA-----GPLLKSSLITPTVAAFPLESADPA-GVAPTTAKGTSTYTT-TASPFLEGTVSL 683
Query: 1430 LETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREP-LPPPAPEPS-PHSG 1487
+ P+ E L + P P P+P+ A+ P +P P PS P +G
Sbjct: 684 APKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG 743
Query: 1488 TPQ---------------PALGQPAPLLPAAVGAVSLATSQ------LPSP-PLGPTVPP 1525
TP P P GA + A+S+ SP PLG +V P
Sbjct: 744 TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSP 803
Query: 1526 Q---PPSALESDGEGPPPRVGFVDSTIKSLDEKL---RTLLYQ--------EHVPTSSAS 1571
Q PP+ + GP +G + S + ++ +L +Q H PT +
Sbjct: 804 QTKRPPT--KKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSP 861
Query: 1572 AGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAP- 1630
G P L P P E + P PKE + P + + +P
Sbjct: 862 KGAPTPSAVTP--LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK 919
Query: 1631 -TRGAVMEQGTSSSMT---AESSPRSMLGYDRDGRQVASDSHVV-------------PSV 1673
R +G +S + A + P + + G S P+
Sbjct: 920 KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979
Query: 1674 PQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRP 1733
P A PA P+ + G P P + + S T + +P
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039
Query: 1734 EQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQT 1793
SPA T +T TL SP P L AP+ P A T
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAA-TLPSPK----GGPATPSLKGAPTPP--------AAT 1086
Query: 1794 ASSIEVGVGEPVSSDSGDEGPRARPPVQK 1822
S + G P S P A PP K
Sbjct: 1087 PPSPKGGPATP-SPKGAPMPPAATPPSPK 1114
Score = 50.1 bits (118), Expect = 2e-05
Identities = 104/457 (22%), Positives = 160/457 (35%), Gaps = 47/457 (10%)
Query: 1340 PEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGA 1399
P Q+ + + + S L+ L Q GP+ PP PA P P++A Q
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPA---PQQCPLSAANQASP 66
Query: 1400 APATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPL--------AVQPLVV 1451
P+ ST+ + T + P + G T+ PL EAP + P +
Sbjct: 67 FPSPSTI----ASTPLEVPFPQSSSG------TALPLGTAPEAPTFLPNLIGPPISPAAL 116
Query: 1452 GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAV-SLA 1510
LA AP T +SAP + S P L P + A G+V +L+
Sbjct: 117 ALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLS 176
Query: 1511 TSQLPSPPL------------GPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRT 1558
PS P P P PP + + + + S + SL + T
Sbjct: 177 APIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPT 236
Query: 1559 LLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGD-QPRSEVCGGDLALPPVPKEAVSGRVQ 1617
P + + V + ++ L+G P + + +LP V +
Sbjct: 237 TTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPN 296
Query: 1618 LPQ--PLVEKSELAPTR----GAVMEQG-TSSSMTAESSPRSM-LGYDRDGRQVASDSHV 1669
P P+ S LAP G+V G T S ++ + +++ + + G S V
Sbjct: 297 TPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSV 356
Query: 1670 VPSVP---QDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARAL 1726
+P +P + VPA V V D G + SS PS V S T
Sbjct: 357 IPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILK 416
Query: 1727 GSPRKRPEQQDVSS-PAKTVGRFSVVSTQDEWTLASP 1762
SP V+ P +VG +V T A+P
Sbjct: 417 SSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAP 453
Score = 50.1 bits (118), Expect = 2e-05
Identities = 63/228 (27%), Positives = 101/228 (44%), Gaps = 28/228 (12%)
Query: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPP 1381
PAP+ +SPP+ SSL + ++ ++ Q AS+ L ++ GP+
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ----ASKGLPAKKGPTALKEVLV 1686
Query: 1382 APLAPSSPPVTAL----PQDGAAPATS--TMPEPASGTASQAGGPGTPQGLTSELETSQP 1435
AP S+P +TA PQ + ATS P+P++ S+ GP + L +
Sbjct: 1687 APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK--GPLSTVAPAPLLPVQKD 1744
Query: 1436 LAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPP-------APEPS---PH 1485
++T + A LAP P +A++ A+A + LP P AP P P
Sbjct: 1745 SSKTAKGKDASHSPKGPLAP--PESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPL 1802
Query: 1486 SGTPQPALGQPAPLLPAAVGAVSLATSQLPSP----PLGPTVPPQPPS 1529
+ +P P L LP++ G V + S+ +P L P +PP+P S
Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPIS 1850
Score = 47.8 bits (112), Expect = 1e-04
Identities = 116/523 (22%), Positives = 175/523 (33%), Gaps = 76/523 (14%)
Query: 1368 LSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427
+S P++P AP+AP P T + P + +P+P P +
Sbjct: 472 ISNIEPTSPAALVMAPVAPKEPS-TQVATTLRIPVSPPLPDPEDLK-------NLPSSVL 523
Query: 1428 SELETSQPL----AETHEAPLAV---------QPLVVGLAPCTPAPEAASTRDASAPREP 1474
+ T + L A AP + P V+ L P + +S+P P
Sbjct: 524 VKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIP 583
Query: 1475 LPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESD 1534
L P A G P P +G+PA + + +G S A+ GP D
Sbjct: 584 LSPEATLAKKSLGEPLP-IGKPASSMTSPLGVNSSASVIKTDSYAGP------------D 630
Query: 1535 GEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPR 1594
GP + + T+ + L + PT+ + GT LE P+
Sbjct: 631 SAGPLLKSSLITPTVAAF--PLESADPAGVAPTT--AKGTSTYTTTASPFLEGTVSLAPK 686
Query: 1595 SE-VCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSM 1653
+ V G L P+ A P P ++ AP V+ S+ + S P +
Sbjct: 687 NHPVKEGTLTTLPLVPTASENCPVAPSP---QNTCAPLATLVLAPEIPKSVPSPSLPPA- 742
Query: 1654 LGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGG 1713
G ++V SH P + PT+ G A SS GT+
Sbjct: 743 -GTPPGTKKVDGISHTSALAP-----VASSPKECPTEDSGASATASS-------KGTLTY 789
Query: 1714 QASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPD- 1772
A P LG ++ P ++ + P +G S + E + +SL + D
Sbjct: 790 LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849
Query: 1773 VYLDEAPSSPDVKLAVRRAQTASSIEVGVGEP---------VSSDSGDEGPRARPPVQKQ 1823
+P+ P K A + GV P V+ EGP P Q
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909
Query: 1824 ASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVP 1866
A S S KKA A P+ G P +PS G P
Sbjct: 910 ALSMTSSS-----PKKARA---TPAPKGI--PASPSPKGAPTP 942
Score = 36.6 bits (83), Expect = 0.28
Identities = 36/151 (23%), Positives = 51/151 (33%), Gaps = 23/151 (15%)
Query: 29 PRAKAARPGPQRFLRRSVVESDQEE------PPGLEAAEAPGPQPPQPLQRRVLLLCKTR 82
P+ A P P++ S+ S ++ P G+ A+ +P P P
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT--------- 946
Query: 83 RLIAERARGRPAAP----APAALVAQPGAP-GAPADAGPEPVGTQEPGPDPIAAAVETAP 137
+G PA P AP A P +P G PA P+ T P P
Sbjct: 947 ---PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003
Query: 138 APDGGPREEAAATVRKEDEGAAEAKPEPGRT 168
+P G P A + AA P+ T
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
Score = 36.2 bits (82), Expect = 0.37
Identities = 40/160 (25%), Positives = 49/160 (30%), Gaps = 14/160 (8%)
Query: 21 AGPAGMAEPRAKAARP-----GPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRV 75
A P+ P AA P GP + PP L+ A P P V
Sbjct: 1233 ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
Query: 76 LLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAG-PEPVGTQEPGPDPIAAAVE 134
+G P PA A + G+PG P G P P P P
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPA-ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351
Query: 135 TAPAPDGGPREEAA-------ATVRKEDEGAAEAKPEPGR 167
T P+ GGP ++ A G A P P R
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391
Score = 34.3 bits (77), Expect = 1.4
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 9/57 (15%)
Query: 90 RGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAA---VETAPAPDGGP 143
+G PA P+P GAP PA P P G+ P P A+ T P+P G P
Sbjct: 997 KGGPATPSPK------GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047
Score = 33.9 bits (76), Expect = 1.8
Identities = 32/101 (31%), Positives = 35/101 (34%), Gaps = 22/101 (21%)
Query: 54 PPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPA-----PAALVAQPGAP 108
PP A P PP P L +G P PA P +A P
Sbjct: 1166 PPPKGAPTTPAATPPSP----------KGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 109 GA---PADAGPEPVG---TQEPGPDPIAAAVETAPAPDGGP 143
GA PA P P G T P P A T P+P GGP
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAA-TPPSPKGGP 1255
Score = 33.5 bits (75), Expect = 2.4
Identities = 37/125 (29%), Positives = 42/125 (33%), Gaps = 16/125 (12%)
Query: 25 GMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRL 84
G A P K A P P S S P A+ P PP P K
Sbjct: 999 GPATPSPKGA-PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP---------KGSPA 1048
Query: 85 IAERARGRPAAPAPAALVAQPGAPGAPADAG-PEPVGTQEPGPDPIAAAVETAPAPDGGP 143
+G P PA A L + G P P+ G P P P P A P+P G P
Sbjct: 1049 ATPLPKGAPTTPA-ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT----PSPKGAP 1103
Query: 144 REEAA 148
AA
Sbjct: 1104 MPPAA 1108
Score = 32.3 bits (72), Expect = 5.3
Identities = 27/88 (30%), Positives = 33/88 (37%), Gaps = 15/88 (17%)
Query: 90 RGRPAAPA---------PAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAA---AVETAP 137
+G P PA PAA GA PA P P G+ P P A T P
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065
Query: 138 APDGGPREEAAATVRKEDEGAAEAKPEP 165
+P GGP A +++ A P P
Sbjct: 1066 SPKGGP---ATPSLKGAPTPPAATPPSP 1090
Score = 32.3 bits (72), Expect = 5.3
Identities = 37/161 (22%), Positives = 55/161 (34%), Gaps = 34/161 (21%)
Query: 8 RDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQP 67
++ P T + PA P P P+ L V S P EA P P
Sbjct: 1568 KEAPATPSSKEASSPPA--VTPSTYKGAPSPKELLIPPAVTS----PSPKEAPTPPAVTP 1621
Query: 68 PQPLQRRVLLLCKTRRLIAERARGRPAAP------------APAALVAQPGAP------G 109
P P + +G P +P +PA++ + GA G
Sbjct: 1622 PSP----------EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671
Query: 110 APADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAAT 150
PA GP + P P + + TAP G ++++AT
Sbjct: 1672 LPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSAT 1712
Score = 31.6 bits (70), Expect = 9.1
Identities = 38/134 (28%), Positives = 42/134 (31%), Gaps = 30/134 (22%)
Query: 54 PPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPA-----PAALVAQP--- 105
PP A P PP P L +G P PA P +A P
Sbjct: 1120 PPHKGAPTTPAATPPSP----------KGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169
Query: 106 GAPGAPADAGPEPVG---TQEPGPDPIAAAVE--------TAPAPDGGPREEAAATVRKE 154
GAP PA P P G T P P A P+P G P AAT
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSP 1228
Query: 155 DEGAAEAKPEPGRT 168
G A P+ T
Sbjct: 1229 KGGLATPSPKGAPT 1242
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 132 bits (331), Expect = 5e-30
Identities = 154/526 (29%), Positives = 196/526 (37%), Gaps = 71/526 (13%)
Query: 630 SSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSV-PA 688
S++++V G +A A + + GP P++ + + A G VG PA
Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA---RRSRAAGTEVGLPRPA 184
Query: 689 PACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPG--QQPP---------PLAQP 737
P+ P P ++S A + P P +P+ G Q+P PL+ P
Sbjct: 185 PSARPRPPTEGPRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 738 T---PLPQVLAPQPVVPLQPVPPHL----PPYLAPASQVGAPAQLKPLQMPQAPLQPLAQ 790
P + P P QP P L PP + P + APA L PL PLA
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA-LGPLSS-----SPLAT 297
Query: 791 VPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATV--PPVPPPQYFSPAVILPSLAAPLP 848
P PP P PP L + P P T ++ P + F P+ L LA P P
Sbjct: 298 PSPSAPPSPSAPP--SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355
Query: 849 PASPAL---PLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQ 905
A PAL PLQA P PP +P P T P AP AL++H A
Sbjct: 356 QAPPALALPPLQAP--PSPPASPPLSPLATPSPQAPN-------------ALAVHLLQAP 400
Query: 906 LPGQPVYPAAFPQMAPTDVPPSPHHTVQNMR----ATPPQPALPPQPTLPPQ-PVLPPQP 960
P P P P P SP T + A PP P P PP P P P
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460
Query: 961 TLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPG 1020
PP PP P P PP PP LP PA P P +P ATP
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520
Query: 1021 SQ--------ILLGHPAPYAVDV--AAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFP 1070
Q +L P+P A A + P P P +V P L L P P + P
Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580
Query: 1071 SSLATVSASVQSVPTQTATLLPPANPPLPGGP---GIASPCPTVQL 1113
SS T+S + + +AT P GP ASP P +L
Sbjct: 581 SS--TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 624
Score = 114 bits (285), Expect = 1e-24
Identities = 129/429 (30%), Positives = 161/429 (37%), Gaps = 61/429 (14%)
Query: 584 PGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADA 643
P P P P A L TLP+ + S +T + GS + S S L LA
Sbjct: 298 PSPSAPPSPSAPPSL--QTLPSPPATPPSQAT--TSLGSPTLQATHSFLPSPPLSPLATP 353
Query: 644 APSPAQCVCSPPVSEGPVLPQSLP-SLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702
P + PP+ P P S P S A P A L V + AP PP P P
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP------PSP 407
Query: 703 AMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPY 762
+ AP PP S P+ PP Q PP LA P P V P P P + P
Sbjct: 408 PVQ-APFSPPASPPVSP---SATPPSQAPPSLAAP--------PLQVPPSPPASPPMSPS 455
Query: 763 LAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI----TPLAGIDGLPP--- 815
P Q P PLQ LA+ PPQ PP PP+ +P A G P
Sbjct: 456 ATPPPQAPPPLAAPPLQ--------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507
Query: 816 --ALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAM-- 871
+LP P AT PP PP +P + +P P PPASP LQA + P PG ++
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVP----PSPPASPT--LQAPRRPPTPGPDTSVSG 561
Query: 872 PCRTIV-----PNAPATIPLLAVAPPGVA--ALSIHSAVAQLPGQPVYPAAFPQMAPTDV 924
P T+ P P+ P ++ P +A + S S +L G P +P
Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP--- 618
Query: 925 PPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLP 981
PP + A PA P P LP P P + T P+ P
Sbjct: 619 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678
Query: 982 PQPMLPPQP 990
L P P
Sbjct: 679 APGALDPGP 687
Score = 94.0 bits (232), Expect = 1e-18
Identities = 162/600 (27%), Positives = 216/600 (36%), Gaps = 118/600 (19%)
Query: 627 DSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP---VLPQSLPSLGAY----QQPTA-- 677
D++ + + AA +P PP S P V P +L LGA ++P A
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
Query: 678 APGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQ-----QPP 732
A G+ ++P A + PA PP T PG + PG+ +P
Sbjct: 62 AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKN---TSPGPVSSPGRASGTTRPG 118
Query: 733 PLAQP---------------TPLPQVLAPQPVVPLQ---PVPPHLPPYLAPASQVGAPAQ 774
PL Q T P+ A P P P +A S+
Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 178
Query: 775 LKPLQMPQAPLQPLAQVPPQM----------PPIPVVPPITPLAGIDGLPPALPDLPTAT 824
P P A +P + P + P P P AG PA L ++
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR-RPSAGGGLQRPASRSLSSSA 237
Query: 825 VPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPN---AP 881
P SPA PS P +PA P Q P P G P + P AP
Sbjct: 238 TP------LSSPARSGPSARGT--PRAPAHPSQ----PKPKGLQALRPPQVTPPRKDAAP 285
Query: 882 ATIPLLA--VAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATP 939
A PL + +A P +A SA L P PA P A T + SP T+Q +
Sbjct: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG-SP--TLQATHSFL 342
Query: 940 PQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPP-QPVLPPQPMLPP-------QPV 991
P P L P T PPQ PP LPP P P PP P+ P P P Q
Sbjct: 343 PSPPLSPLATPPPQA--PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 992 LPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLS 1051
P P+ PV+ P P +P+ATP SQ AP ++ P + VPP+ S
Sbjct: 401 FSPPPSPPVQA-PFSPPASPPVSPSATPPSQ------APPSL----AAPPLQVPPSPPAS 449
Query: 1052 PPLPEVLLP--------AAPELL-----PQFPSSLATVSASVQSVPTQTAT--------- 1089
PP+ P AAP L PQ P +LAT +Q++P+ A+
Sbjct: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT--PPLQALPSPPASFPGQAPFSP 507
Query: 1090 -----LLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVT 1144
+ P A PP P +A+ P +Q+ P + P P S G +T
Sbjct: 508 SASLPMSPLATPPPQAPPVLAA--PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 565
Score = 71.6 bits (174), Expect = 8e-12
Identities = 104/406 (25%), Positives = 141/406 (34%), Gaps = 64/406 (15%)
Query: 1323 APEAPESSPPLPLSSL-PPEAS---QDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPG 1378
AP P P L +L PP+ + +D+AP LSS S LA+ + PS PP
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS----SPLATPSPSAPPSPSAPPS 311
Query: 1379 APPAPLAPSSPPVTALPQDGAAPATST---MPEPASGTASQAGGPGTPQGLTSELETSQP 1435
P P++PP A G+ +T +P P + P P L + P
Sbjct: 312 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP-PQAPPAL------ALP 364
Query: 1436 LAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQ 1495
+ +P A PL P AP A + AP P PP P +P S P +
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-PPSPPVQAPFSPPASPPVSP 423
Query: 1496 PAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEK 1555
A P + SLA L PP P PP PSA + PPP K +
Sbjct: 424 SAT--PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP-QAPPPLAAPPLQLAKPPPQA 480
Query: 1556 LRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPP--VPKEAVS 1613
L S A P G F+ P + + LA PP P +
Sbjct: 481 PPALATPPLQALPSPPASFP---GQAPFS--------PSASLPMSPLATPPPQAPPVLAA 529
Query: 1614 GRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGY--------------DRD 1659
+Q+P +PT A T T+ S PR L
Sbjct: 530 PLLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 585
Query: 1660 GRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPP 1705
G +A S S P+++ + D G G ++A PPP
Sbjct: 586 GPDLAGHSSSATSTPEELRGY-----------DSGPEGGAAASPPP 620
Score = 62.8 bits (151), Expect = 4e-09
Identities = 152/617 (24%), Positives = 205/617 (33%), Gaps = 98/617 (15%)
Query: 1319 AEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPG 1378
A PA AP P P S P A + ++ +++ G + P
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 1379 APPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG----GPGTPQGLTSELETSQ 1434
AP A +S P + + A PA +T P P S +G GP +GL E +
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 1435 PLAETHEAP------LAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGT 1488
+ EAP + G P TP+P A A+ LP PAP P T
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193
Query: 1489 PQP----------ALGQPAPLL---PAAVGAV------SLATSQLP--SP---------- 1517
P + +P+P P+A G + SL++S P SP
Sbjct: 194 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 253
Query: 1518 PLGPTVPPQPP----SALESDGEGPP-----PRVGFVDST-----------IKSLDEKLR 1557
P P P QP AL PP P +G + S+ S L+
Sbjct: 254 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313
Query: 1558 TLLYQEHVPTSSA--SAGTPVEVGDRDF----TLEPLRGDQPRSEVCGGDLALPPVPKEA 1611
TL P S A S G+P F L PL P++ LALPP+
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA---LALPPLQAPP 370
Query: 1612 VSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVP 1671
PL S AP AV + + SP + S S P
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAV--HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 428
Query: 1672 SVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGG---QASHPQTLGARALGS 1728
S Q P+ P P SA PPP + Q + P AL +
Sbjct: 429 S--QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486
Query: 1729 PRKRPEQQDVSSPAKTVGR--FSVVSTQDEWTLAS--PHSLRYSAPPDVYLDEAPSSPDV 1784
P P Q S PA G+ FS ++ LA+ P + A P + + +P +
Sbjct: 487 P---PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543
Query: 1785 KLAVRRAQTASSIEVGVGEPVSSDSGDE-----GPRARPPVQKQASLPVSGSVAGDFVKK 1839
A RR T P +S SG P PP + S +SG
Sbjct: 544 LQAPRRPPTPG--------PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595
Query: 1840 ATAFLQRPSRAGSLGPE 1856
AT+ R GPE
Sbjct: 596 ATS-TPEELRGYDSGPE 611
Score = 53.5 bits (127), Expect = 2e-06
Identities = 103/424 (24%), Positives = 154/424 (36%), Gaps = 54/424 (12%)
Query: 1452 GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLAT 1511
G A TPA A P P PPP P+ PL A G + AT
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA-GGIGGAT 69
Query: 1512 SQLPSPPLGPTVPPQPPSA--------LESDGEGPPPRVGFVDSTIK--SLDEKLRTLLY 1561
+P GPT +PP++ ++ GP G T + L +K +
Sbjct: 70 IPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129
Query: 1562 QEHVPTSSASAG---TPVEVGDRDFTLEPLRGDQP-----RSEVCGGDLALP-PVPKEAV 1612
+E V A+ + + G R T P G RS G ++ LP P P
Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189
Query: 1613 SGRVQLPQPLV---------EKSELA---PTRGAVMEQGTSSSMTAESSPRSMLGYDRDG 1660
+ P+ V E S A P+ G +++ S S+++ ++P S
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 249
Query: 1661 RQVASDSHVVPSVPQDVP-AFVRPARVEPTDRDGGEA-GESSAEPPPSDMGTVGGQASHP 1718
+ + PS P+ +RP +V P +D A G S+ P + + S P
Sbjct: 250 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP 309
Query: 1719 QTLGARALGSPRKRPEQQDVSSPAKTV--GRFSVVSTQDEWTLASPHSLRYSAPPDVYLD 1776
+L + L SP P Q +S S + + LA+P APP + L
Sbjct: 310 PSL--QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP---QAPPALALP 364
Query: 1777 --EAPSSPDVK-----LAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVS 1829
+AP SP LA Q +++ V + + S P PPVQ S P S
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS------PPPSPPVQAPFSPPAS 418
Query: 1830 GSVA 1833
V+
Sbjct: 419 PPVS 422
Score = 53.1 bits (126), Expect = 3e-06
Identities = 72/245 (29%), Positives = 95/245 (38%), Gaps = 39/245 (15%)
Query: 1322 PAPEAPE--SSPPLPLSSLPPEASQDSA-PYKDQLSSKE-----QPSFLASQQLLSQAGP 1373
P P+AP ++PPL L+ PP+A A P L S Q F S L
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 1374 SNPPGAPP---APL--APSSPPVTALPQDGAAPATSTMPEPASG---TASQAGGPGTPQG 1425
+ PP APP APL P SPP + Q P T SG T + A GP P
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577
Query: 1426 LTSELETSQPLAETHEAPLAVQPLVV--------GLAPCTPAPEA--ASTRDASAPREPL 1475
+ S P H + P + G A +P P+A A+ A+ R P
Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 637
Query: 1476 PPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDG 1535
PP A +P + P P PA +A G ++ ++ GP P AL+
Sbjct: 638 PPLAFRGAPGAPLPWP----PATGPGSADGLCTIYETE------GPESATPAPGALD--- 684
Query: 1536 EGPPP 1540
GP P
Sbjct: 685 PGPSP 689
Score = 46.6 bits (109), Expect = 3e-04
Identities = 69/237 (29%), Positives = 89/237 (37%), Gaps = 46/237 (19%)
Query: 1322 PAPEAPES--SPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQL-------LSQAG 1372
P P+AP + +PPL PP + AP+ S P Q L Q
Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535
Query: 1373 PSNPPGAPP--APLAPSSP-PVTAL--PQDGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427
PS PP +P AP P +P P T++ P+ A A P P+ +S GP +
Sbjct: 536 PS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594
Query: 1428 SELETSQPLAETHEAP----LAVQPLVVGLAPCTPAP----EAASTRDASAPREPLP-PP 1478
S T + L P A P LA C PA A AP PLP PP
Sbjct: 595 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 654
Query: 1479 A-----------------PE---PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLP 1515
A PE P+P + P P+ G AA GA + A+S+ P
Sbjct: 655 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAGAGASSRSP 709
Score = 37.4 bits (85), Expect = 0.17
Identities = 32/120 (26%), Positives = 42/120 (35%), Gaps = 9/120 (7%)
Query: 11 PGTLMEPGRGAG---PAGM-----AEPRAKAARPGPQ-RFLRRSVVESDQEEPPGLEAAE 61
P P G G PA A P + AR GP R R+ Q +P GL+A
Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 272
Query: 62 APGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGT 121
P PP+ L + L P+ AP +L P P P +G+
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332
Score = 36.6 bits (83), Expect = 0.28
Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 4/97 (4%)
Query: 55 PGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPG-APGAPAD 113
P + + P PQ P PL L L K P P+ + PG AP +P+
Sbjct: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509
Query: 114 AGP-EPVGTQEPGPDPIAAA--VETAPAPDGGPREEA 147
+ P P+ T P P+ AA ++ P+P P +A
Sbjct: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546
Score = 36.2 bits (82), Expect = 0.37
Identities = 49/170 (28%), Positives = 61/170 (35%), Gaps = 29/170 (17%)
Query: 21 AGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQP--------PQPLQ 72
AG G A A R GP R R + PP + P P P PL
Sbjct: 62 AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 121
Query: 73 RRVLLLCKTRRLIAER--ARGRPA-APAPAALVAQPGAPGAPAD-AGPEPVGTQEPGPDP 128
++ L R+ AE ARG+ AP +AL A GA D +GP P GT P
Sbjct: 122 QKGL------RISAEETVARGKATEAPKRSALSA-----GARRDTSGPTP-GTPSPAMAR 169
Query: 129 IAAAVET-----APAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEP 173
+ A T PAP PR + + + EP R P
Sbjct: 170 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 219
Score = 32.3 bits (72), Expect = 5.3
Identities = 44/166 (26%), Positives = 51/166 (30%), Gaps = 18/166 (10%)
Query: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQP 70
P L P P+ A P +A R P SV P L A APGP PP
Sbjct: 524 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV------SGPRLTLALAPGPPPPPS 577
Query: 71 LQRRVLLL-------CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQE 123
L + E RG + P A + P P A A ++
Sbjct: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP--PDAELAACHPAAWSRG 635
Query: 124 PGPDPIAAAVETAP---APDGGPREEAAATVRKEDEGAAEAKPEPG 166
P P AP P GP E EG A P PG
Sbjct: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 130 bits (326), Expect = 2e-29
Identities = 153/544 (28%), Positives = 211/544 (38%), Gaps = 93/544 (17%)
Query: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSP---AQCVCSPPVSE----GP 660
TSL+S S+ SG S+ +SQS+ + ++D P+ +Q + S SE G
Sbjct: 527 TSLSS-SSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGT 585
Query: 661 VLPQSLPS-LGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPT 719
L +S + + + +P + P+ P P + Q +P LPPP P P
Sbjct: 586 QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQP--------SPPLPPPPPPPPP 637
Query: 720 GPGQPAPPGQQPPPL-AQPTPLPQVLAPQ-----PVVPLQPVPPHLPPYLAPASQVGAPA 773
P P PP PPPL +Q P AP + LQ H P + P
Sbjct: 638 PPPPPPPP---PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP---PV 691
Query: 774 QLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPA--LPDLPTATVPPVPPP 831
PQ + P VPP PP PP TP + + L PA P LP + PP PP
Sbjct: 692 MQSQSVKPQILVPPNGVVPPPPPP---PPPPTPGSAMAQLKPAPCAPSLPQFSAPP--PP 746
Query: 832 QYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAP 891
+ +A P PP P +P P PP AP P + AP + +A
Sbjct: 747 LKIHQVQHITQVAPPTPPPPPPIPA-----PLPPQAP---PKPLVTIPAPTSTKTVAPVV 798
Query: 892 PGVAALSIHSAVAQLPGQPVYPAAF----PQMAPTDVPPSPHHTVQNMRATPPQPALPPQ 947
A + V QP +PA++ P P VPP Q+ A PP L P
Sbjct: 799 TQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPV 858
Query: 948 PTL--------PPQPVLPPQPTLPPQPV-------LPP----QPTRPPQPVLPPQPMLPP 988
P++ PP P P + P +PV PP +P P + P P PP
Sbjct: 859 PSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPP 918
Query: 989 QP-----VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAA----QV 1039
P V PP P PV P P P A+P TP G P ++ +
Sbjct: 919 PPPESSLVFPPPPPSPVPAPPPPP--PPTASP--TPDKS---GSPGKKTSKTSSPGGKKP 971
Query: 1040 PTVPVPPAAVLSPP---LPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANP 1096
P P +++ S PE P+ L+ +F + S S +++P PPA P
Sbjct: 972 PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLP-------PPAAP 1024
Query: 1097 PLPG 1100
P PG
Sbjct: 1025 PKPG 1028
Score = 89.4 bits (220), Expect = 4e-17
Identities = 167/689 (24%), Positives = 229/689 (33%), Gaps = 180/689 (26%)
Query: 529 AKSIRDRVALIQWRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPE 588
++SI V W+R + + P + PP+ Q ++ A QP PP
Sbjct: 569 SQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPL 628
Query: 589 PEEPEADQHLLPPTLP--------------TSATSLASDSTFDSGQGSTVYS-------- 626
P P PP P ++A ST Q ++ +S
Sbjct: 629 PPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPT 688
Query: 627 ----DSQSSQQSVML------------------GSLADAAPSPAQCVCSPPVSEGPVLPQ 664
SQS + +++ GS A A PA C S P P P
Sbjct: 689 PPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS-AMAQLKPAPCAPSLPQFSAPPPPL 747
Query: 665 SLPSLGAYQQ---PTAAPGLPVGSVPAPACPPSLQQHFPDPAMS--FAPVL-----PPPS 714
+ + Q PT P P+ + P PP P P + APV+ P P+
Sbjct: 748 KIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPT 807
Query: 715 TPMPTGPGQPA------PPGQQPPPLAQPTP-LPQ---VLAPQPVVPLQPVP-------- 756
P+P QPA PP PP+ P P LP+ A P PL PVP
Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIAS 867
Query: 757 ----PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPL-AQVPPQMPPIPVVPPITPLAGID 811
P PP M PL+P+ A V PQ PP P
Sbjct: 868 QFPPPPTPP-----------------AMESQPLKPVPANVAPQSPPAVKAKP-------K 903
Query: 812 GLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAM 871
P ++P +P+ PP PPP+ SL P PP SP V P PP P A
Sbjct: 904 WQPSSIP-VPSPDFPP-PPPE--------SSLVFPPPPPSP------VPAPPPPPPPTAS 947
Query: 872 PCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHT 931
P P+ + PG S + P PP+P
Sbjct: 948 P----TPDKSGS--------PGKKTSKTSSPGGKKP-----------------PPTPQ-- 976
Query: 932 VQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPV 991
+N A P+P P L + T P + P + T PP P
Sbjct: 977 -RNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP-------------PA 1022
Query: 992 LPPQPA-LPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPA-AV 1049
PP+P L + L L + A P +L G V+ P PP+ +
Sbjct: 1023 APPKPGKLNLSGVNLPGVLQQGCVSAKAP---VLSGRGKDSVVE-------FPSPPSDSD 1072
Query: 1050 LSPPLPEVLLPAAPELLPQ-FPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPC 1108
PP PE LP P +P F + + A V P Q + + PP P
Sbjct: 1073 FPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPP----PTRPKRN 1128
Query: 1109 PTVQLTVEPVQEEQASQDKPPGLPQSCES 1137
+ +LT + E+ P +P S +S
Sbjct: 1129 DSTRLTQAEISEQPTMATVVPQVPTSPKS 1157
Score = 68.9 bits (167), Expect = 5e-11
Identities = 63/242 (26%), Positives = 91/242 (37%), Gaps = 33/242 (13%)
Query: 1324 PEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP--P 1381
P P PP P S++ AP Q S+ P + Q ++Q P PP P P
Sbjct: 711 PPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIP 770
Query: 1382 APLAPSSP--PVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAET 1439
APL P +P P+ +P AP ++ P A+ P TP + +
Sbjct: 771 APLPPQAPPKPLVTIP----APTSTKTVAPVVTQAA----PPTPTPPVPPAKKQPAFPAS 822
Query: 1440 HEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLP----------PPAPEPSPHSGTP 1489
+ P P V P P ++ + +P P+P PP P P P
Sbjct: 823 YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP 882
Query: 1490 -QPALGQPAPLLPAAVGA--------VSLATSQLPSPPLGPTV--PPQPPSALESDGEGP 1538
+P AP P AV A + + + P PP ++ PP PPS + + P
Sbjct: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPP 942
Query: 1539 PP 1540
PP
Sbjct: 943 PP 944
Score = 66.6 bits (161), Expect = 3e-10
Identities = 68/250 (27%), Positives = 84/250 (33%), Gaps = 39/250 (15%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEAS--------------QDSAPYKDQLSSKEQPSFL 1362
P P P P PPLP S P S Q+++ + L P +
Sbjct: 633 PPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVM 692
Query: 1363 ASQQLLSQA-----GPSNPPGAPPAPLAPSS--------PPVTALPQDGAAPATSTMPEP 1409
SQ + Q G PP PP P P S P +LPQ A P + +
Sbjct: 693 QSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV 752
Query: 1410 ASGTASQAGGPGTPQGLTSELETSQPLAE--THEAPLA---VQPLVVGLAPCTPAPEAAS 1464
T P P + + L P T AP + V P+V AP TP P
Sbjct: 753 QHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP 812
Query: 1465 TRDASA------PREPLPPPAPEPSPHSGTPQPALGQPAPL-LPAAVGAVSLATSQLPSP 1517
+ A P P PP P P P Q +P P L V SQ P P
Sbjct: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872
Query: 1518 PLGPTVPPQP 1527
P P + QP
Sbjct: 873 PTPPAMESQP 882
Score = 64.7 bits (156), Expect = 1e-09
Identities = 62/232 (26%), Positives = 81/232 (34%), Gaps = 30/232 (12%)
Query: 1323 APEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPA 1382
AP +++PP P +PP +K+QP+F AS P +PP
Sbjct: 795 APVVTQAAPPTPTPPVPP--------------AKKQPAFPASY----------IPPSPPT 830
Query: 1383 PLAPSSPPVTALPQDGAA----PATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAE 1438
P P PP Q A S +P ASQ P TP + S+ P
Sbjct: 831 PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV 890
Query: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAP 1498
++P AV+ P P PPP P P P P P P P
Sbjct: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTP 950
Query: 1499 LLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDG-EGPPPRVGFVDSTI 1549
+ G + TS P P P + S S G E P P+ VDS +
Sbjct: 951 DKSGSPGKKTSKTSS-PGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLV 1001
Score = 63.9 bits (154), Expect = 2e-09
Identities = 56/222 (25%), Positives = 76/222 (34%), Gaps = 34/222 (15%)
Query: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK--EQPSFLASQQLLSQAGPSNPPGA 1379
P P P PP P PP SAP + + + Q +G P
Sbjct: 629 PPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPT 688
Query: 1380 PPAPLAPSSPPVTALPQDGAAPATSTMPEPAS-GTASQAGGPGTPQGLTSELETSQPLAE 1438
PP + S P +P +G P P P + G+A P + P +
Sbjct: 689 PPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLK 748
Query: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAP 1498
H+ Q +AP TP P PPP P P P P+P + PAP
Sbjct: 749 IHQVQHITQ-----VAPPTPPP---------------PPPIPAPLPPQAPPKPLVTIPAP 788
Query: 1499 LLPAAVG-AVSLATSQLPSPPLGPT----------VPPQPPS 1529
V V+ A P+PP+ P +PP PP+
Sbjct: 789 TSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPT 830
Score = 63.9 bits (154), Expect = 2e-09
Identities = 71/221 (32%), Positives = 83/221 (37%), Gaps = 29/221 (13%)
Query: 1322 PAPEAPESSP--PLPLSSLPPEASQDSAPYKDQLSSKEQPS--FLASQQLLSQAGPSNPP 1377
P P A ES P P+P + P A K Q SS PS F S P PP
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932
Query: 1378 GAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGG---PGTPQGLTSELETSQ 1434
PAP P PP TA P P S P + S GG P TPQ S +++S
Sbjct: 933 SPVPAP--PPPPPPTASP----TPDKSGSPGKKTSKTSSPGGKKPPPTPQ-RNSSIKSSS 985
Query: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPH----SGTPQ 1490
+V LV P PA S +E LPPPA P P SG
Sbjct: 986 GAEHPEPKRPSVDSLVSKFTP--PA------ESGSPSKETLPPPAAPPKPGKLNLSGVNL 1037
Query: 1491 PAL---GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPP 1528
P + G + P G + + PSPP PP PP
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPP 1078
Score = 49.3 bits (116), Expect = 4e-05
Identities = 95/445 (21%), Positives = 143/445 (32%), Gaps = 61/445 (13%)
Query: 1447 QPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL----LPA 1502
+P + P +P P+ + AS P PLPPP P P P P P P PL P+
Sbjct: 600 RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP---PPPPLPSQSAPS 656
Query: 1503 AVGAVSL------------------ATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGF 1544
A A + A + P+PP+ + +P + +G PPP
Sbjct: 657 AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPP 716
Query: 1545 VDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLAL 1604
T S +L+ +P SA P+++ + P
Sbjct: 717 PPPTPGSAMAQLKPAPCAPSLPQFSAPP-PPLKIHQVQHITQVAPPTPP----------- 764
Query: 1605 PPVPKEAVSGRVQLPQPLVEKSELAPTR--GAVMEQGTSSSMTAESSPRSMLGYDRDGRQ 1662
PP P A P+PLV T+ V+ Q + T P +Q
Sbjct: 765 PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK--------KQ 816
Query: 1663 VASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLG 1722
A + +P P P V P + + S P PS + + Q P T
Sbjct: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876
Query: 1723 ARALGSPRKRPEQQDVSSPAKTVGR-----FSVVSTQDEWTLASPHSLRYSAPPDVYLDE 1777
A + P SP + S+ ++ P S PP
Sbjct: 877 AMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVP 936
Query: 1778 APSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFV 1837
AP P A + S G+ S S G + P Q+ +S+ S
Sbjct: 937 APPPPPPPTASPTPDKSGS----PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992
Query: 1838 KKAT-----AFLQRPSRAGSLGPET 1857
K+ + + P+ +GS ET
Sbjct: 993 KRPSVDSLVSKFTPPAESGSPSKET 1017
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 129 bits (324), Expect = 3e-29
Identities = 181/697 (25%), Positives = 254/697 (36%), Gaps = 154/697 (22%)
Query: 549 ALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEP-EADQHLLPPTLPTSA 607
++QPKE P PLQ + +AG P+ E P + LLPP +
Sbjct: 403 SMQPKE-------------PGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPL 449
Query: 608 TSLASDS-TFDSGQGSTVYSDSQSSQQSVMLGSL--------ADAAPSPAQCVCSPPVSE 658
+ +S T + S + + S + +L + +P P + SPP
Sbjct: 450 SPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509
Query: 659 GPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP 718
P P L ++ +P L P P P P +P+ PPP +P
Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPL------SPPFEESPLSPPPE-ELP 562
Query: 719 TGPGQPA----PPGQQPP--------PLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAP- 765
T P A PP ++ P P++ P ++ P PL P PP P P
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP-PPEESPLSPPP 621
Query: 766 -ASQVGAPAQLKPLQMP--QAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPT 822
AS++ P + P+ P ++P+ P +V ++ P+PVV ++P L P + PT
Sbjct: 622 EASRLSPPPEDSPMSPPPEESPMSPPPEV-SRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
Query: 823 ATVPPV----PPPQYFSPAVILPSLAAPLPPASPALP-----LQAVKLPHPPGAPLAMPC 873
+ P PPP+ S +P P SPA P L ++ L P PL
Sbjct: 681 SPPPEASRLSPPPE--------DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL---- 728
Query: 874 RTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQ 933
P P P + P LS L +P P PQ + P P
Sbjct: 729 ----PEEPQLCP-RSEGP----HLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPC- 778
Query: 934 NMRATPPQPALPPQ---PTLPPQP---------------VLPPQPTLPPQPV---LPPQP 972
+ A P +P L PQ P L PQP +P +P L PQP L PQ
Sbjct: 779 -LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS 837
Query: 973 TRPPQPVLPPQPMLPPQPVLPPQPALPVRP--EPLQPHLPEQA---APAATPGSQILLGH 1027
P P + L P+ PP P +P EP Q PE+ P P LLG
Sbjct: 838 EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
Query: 1028 PA------PYAVDVAAQVPTVP---------VPPAAVLSPPLPEVLLPAAPELL------ 1066
PA P + ++P P + P L PPL ++ AAP L
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957
Query: 1067 -----------PQFPSSLATVSASVQSVPTQTAT----LLPPANPPLPGGP-GIASP--- 1107
P+ P + + + P T + P PP PG P G ASP
Sbjct: 958 EYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM 1017
Query: 1108 -------CPTVQLTVEPVQEEQASQDKPPGLPQSCES 1137
P +Q ++ P Q SQ PP LP S S
Sbjct: 1018 EPLPPQCSPLLQHSLVP-QNSPPSQCSPPALPLSVPS 1053
Score = 98.6 bits (244), Expect = 6e-20
Identities = 187/719 (26%), Positives = 258/719 (35%), Gaps = 148/719 (20%)
Query: 552 PKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLA 611
P+E P+ +R P+P+ +++ PP E P + PT P S
Sbjct: 639 PEESPMSPPPEVSRLSPLPVVSRLS---------PPPEESPLSPPPEESPTSPPPEASRL 689
Query: 612 SDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGA 671
S DS S DS +S P P + S P+ E P+LP LP
Sbjct: 690 SPPPEDSPT-SPPPEDSPAS-------------PPPEDSLMSLPLEESPLLP--LPEEPQ 733
Query: 672 YQQPTAAPGLPVGSVPAPACP---PSLQQHFPDPAMSFAPVLPPPSTP-MPTGPGQPAPP 727
+ P L P P P P ++ P + P P P + P +P
Sbjct: 734 LCPRSEGPHLS----PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLS 789
Query: 728 GQQPPPLAQPTPLPQVLAPQPVVP-LQPVPPHLPPYLAPASQVG--APAQLKPLQMP--- 781
Q P P P L+PQ P L PVP P L+P + +P +P P
Sbjct: 790 PQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE--PCLSPQPEESHLSPQSEEPCLSPRPE 847
Query: 782 QAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILP 841
++ L P + PP + P P PP P G PA +LP P P SP + P
Sbjct: 848 ESHLSPELEKPP-LSPRPEKPPEEP-----GQCPAPEELPLFPPPGEPS---LSPLLGEP 898
Query: 842 SLAAPLPPASPALPLQAVKLP--HPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSI 899
+L+ P P LP + P P +P MP + P P + + A APP ++ L
Sbjct: 899 ALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPP--PLSPIITAAAPPALSPLGE 956
Query: 900 --HSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPV-- 955
+ A+ P P A P + T + P P + PP LPP P P P
Sbjct: 957 LEYPFGAKGDSDPESPLAAP-ILETPISPPPEANCTDPEPVPPM-ILPPSPGSPVGPASP 1014
Query: 956 -----LPPQ------PTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVL------------ 992
LPPQ +L PQ P Q + P P+ P P+ P V+
Sbjct: 1015 ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEME 1074
Query: 993 ------PPQPAL-PVRPEPLQPHLPEQAAPAATPGSQI-----LLGHPAPY-AVDVAAQV 1039
P PAL P PL + + + PA +P + L AP +D
Sbjct: 1075 TEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQ 1134
Query: 1040 PTVPVPPAAVL-----SPPL--PEVLLPAAP-ELLPQFPSSLATVS-ASVQSVPTQTATL 1090
P P ++ SP L PE L P P E+ P+ + S Q P
Sbjct: 1135 PEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP 1194
Query: 1091 LPP------------------ANPPLPGG-PGIASPCPT----------VQLTVEPVQEE 1121
PP A+ PG P + SP P V V P ++E
Sbjct: 1195 TPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDE 1254
Query: 1122 QASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSR 1180
+ + LP++ +S L A GG+ EG R RRS+ ARSR
Sbjct: 1255 GSLRLCTDSLPETDDS-----------LLCDAGTAISGGKAEGEKGR---RRSSPARSR 1299
Score = 87.4 bits (215), Expect = 1e-16
Identities = 127/497 (25%), Positives = 171/497 (34%), Gaps = 101/497 (20%)
Query: 674 QPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPP-----STPMPTGPGQPAPPG 728
QP L + P L+ P P+LPPP S P P P P
Sbjct: 405 QPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEA 464
Query: 729 QQ--PPPLAQP-TPLPQVL---APQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQ 782
+ PPP P +PLP+ L P PL P P P P S +P + PL P+
Sbjct: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE 524
Query: 783 -APLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILP 841
+P P + P + P P P++P L P +LPT+ PPP+
Sbjct: 525 ESPPSPALETP--LSPPPEASPLSPPFEESPLSPPPEELPTS-----PPPE--------A 569
Query: 842 SLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHS 901
S +P P SP P P +P++ P P A P
Sbjct: 570 SRLSPPPEESPMSP-------PPEESPMSPP-----PEASRLFP---------------- 601
Query: 902 AVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPT 961
P+ P P+ +P PP + R +PP P P P+ PP
Sbjct: 602 ---PFEESPLSPP--PEESPLSPPP------EASRLSPPPEDSPMSPPPEESPMSPPPEV 650
Query: 962 --LPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATP 1019
L P PV+ P + L P P P P L PE P + +PA+ P
Sbjct: 651 SRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP 710
Query: 1020 GSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSP--------PLPE----VLLPAAPELLP 1067
L+ P + P +P+P L P P PE P P L P
Sbjct: 711 PEDSLMSLP-------LEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSP 763
Query: 1068 QFPSSLATVSASVQSVPTQTATLLPPANP---PLPGGPGIASPCPTVQLTVEPVQEE--- 1121
Q + P + P P P GP + SP P +L + P EE
Sbjct: 764 Q------AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL-SPQPE-ELHLSPQTEEPHL 815
Query: 1122 QASQDKPPGLPQSCESY 1138
++P PQ ES+
Sbjct: 816 SPVPEEPCLSPQPEESH 832
Score = 79.0 bits (193), Expect = 5e-14
Identities = 153/584 (26%), Positives = 194/584 (33%), Gaps = 129/584 (22%)
Query: 626 SDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGS 685
++SQ ++Q+ +G +A PA + PP P +L S P AAP + +GS
Sbjct: 2080 AESQINKQT-KVGDIARKTDRPALHLRIPPQ------PGALGS----PPPAAAPTIFIGS 2128
Query: 686 VPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLA 745
PA + F P P S P P PG+ + PP + P
Sbjct: 2129 PTTPAGLSTSADGFLKP--------PAGSVPGPDSPGELFL--KLPPQVPAQVPSQDPFG 2178
Query: 746 PQPVVPLQPVPPHLPPYLAP-ASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI 804
P PL+P P PP P S GAPAQ
Sbjct: 2179 LAPAYPLEPRFPTAPPTYPPYPSPTGAPAQ------------------------------ 2208
Query: 805 TPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAP-LPPASPALPLQAVKLPH 863
P+ G P A T PP P PS P L P P+L AV P
Sbjct: 2209 PPMLGASSRPGAGQPGEFHTTPPGTPRHQ-------PSTPDPFLKPRCPSLDNLAV--PE 2259
Query: 864 PPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQL-PGQPVYPAAFPQMAPT 922
PG V A+ PLL+ P G + ++ +L P Y P +
Sbjct: 2260 SPG----------VGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGP--PNLGFV 2307
Query: 923 DVPPSPHH----------------TVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQP 966
D P S H T + + P P L +P P PP L P P
Sbjct: 2308 DSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP-----PPAQALAPSP 2362
Query: 967 VLPPQPTRPPQPVLP-PQPMLPPQPVLPPQP---ALPVRPEPLQPHLPEQAAPAATPGSQ 1022
P RP P QP L P+P PP ALP R P P A+P + SQ
Sbjct: 2363 PSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQ 2422
Query: 1023 ILLGHPAPYAVDVAAQVPTVP---VPPAAVLSPPLPEVLLPAAPELLPQFP--------- 1070
L P P + + P P P P P+ P AP P P
Sbjct: 2423 SPL-TPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKA 2481
Query: 1071 SSLATVSASVQSVPT--------QTATLLPPANPP----LPG-GPGIASPCPTVQLTVEP 1117
SLA S P + +P PP PG G + +P P +
Sbjct: 2482 GSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQA 2541
Query: 1118 VQEEQASQDKP-PGL--PQSCESYGGSDVTSGKELSDSCEGAFG 1158
V E P PGL P S+ G T GK S + A G
Sbjct: 2542 VGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATG 2585
Score = 75.1 bits (183), Expect = 7e-13
Identities = 101/360 (28%), Positives = 140/360 (38%), Gaps = 56/360 (15%)
Query: 1285 LGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQ 1344
LG + Q AP+ ++ L + P E P PE SP P PPEAS+
Sbjct: 419 LGKAGVQLEPQLEAPLNEEMPL--------LPPPEESPLSPPPEESPTSP----PPEASR 466
Query: 1345 DSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATS 1404
S P ++L + P L + L ++ S PP P P S P + L + +P
Sbjct: 467 LSPP-PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE 525
Query: 1405 TMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAAS 1464
+ P PA T P +P S L S P E+PL+ P + P +P PEA
Sbjct: 526 SPPSPALET------PLSPPPEASPL--SPPF---EESPLSPPPEEL---PTSPPPEA-- 569
Query: 1465 TRDASAPREPLPPPAPEPSPHSGTPQPALGQP----APLLP----AAVGAVSLATSQLPS 1516
+R + P E P PE SP S P+ + P +PL P + + A+ P
Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP 629
Query: 1517 PPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPV 1576
P P PP S + PPP V S + L R E P S +P
Sbjct: 630 PEDSPMSPPPEESPM-----SPPPEV----SRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
Query: 1577 EVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLP------QPLVEKSELAP 1630
L P D P S A PP P++++ + LP PL E+ +L P
Sbjct: 681 SPPPEASRLSPPPEDSPTSPPPEDSPASPP-PEDSL---MSLPLEESPLLPLPEEPQLCP 736
Score = 60.5 bits (145), Expect = 2e-08
Identities = 240/1077 (22%), Positives = 348/1077 (32%), Gaps = 251/1077 (23%)
Query: 628 SQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVP 687
SQ QS LG L P PAQ + P S + G+Y P A P L P
Sbjct: 2336 SQVEPQSPGLG-LRPQEPPPAQALAPSPPSHPDIFRP-----GSYTDPYAQPPLTPRPQP 2389
Query: 688 AP-----ACPPSLQQHFPDPAMSFAPVLPP-------PSTPMPTG-----PGQPAPPGQQ 730
P A PP + P S P P P TP P P P Q
Sbjct: 2390 PPPESCCALPP---RSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS 2446
Query: 731 PPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLK----PLQMPQAPLQ 786
P P ++P PQ + P PL P PP +A + A L P +P P
Sbjct: 2447 PDPYSRPPSRPQ--SRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG 2504
Query: 787 PL-AQVPPQMPPIPVVPPITPLAGIDGLPPAL----------PDL-PTATVPPVPPPQ-- 832
L A+VP PP V P T G P + P L P P +PPP
Sbjct: 2505 ELHAKVPSGQPPNFVRSPGT--GAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI 2562
Query: 833 --YFSPAVIL----------------PSLAAPLPPASPAL-------PLQAVKLPHPPGA 867
+F P L PS +PL P+S + PL+ + PP
Sbjct: 2563 NSHFGPGPTLGKPQSTNYTVATGNFHPS-GSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621
Query: 868 PLAMPCR---------------------TIVPNAPATIPLLAVAPPGVAALSIHSAVAQL 906
++P T + ++ AT L PG++ LS Q
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681
Query: 907 PGQPVYPAAFPQMAPTDVPPSPHHTVQNMR-ATPPQPALPPQPTLPPQPVLPPQPT---- 961
Q + Q + T A P + +P+ P L T
Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAG 2741
Query: 962 ---------LPPQ----PVLPP-------QPTRPPQPVLPPQPMLPPQPVL--------- 992
LPP P+L P + +RPP P P + + ++
Sbjct: 2742 TQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQR 2801
Query: 993 -PPQPALPVRPEPLQPHLPEQAAPA------------ATPGSQI---LLGHPAPYAVDVA 1036
P +LP++ + Q +QA A +TPG ++ LG P +
Sbjct: 2802 APYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLA-GISTR 2860
Query: 1037 AQVPTVPVP----PAAVLS-------------PPLPEVLLPAAPELLP--QFPSSLATVS 1077
P PVP PA + P P P P P + P LA
Sbjct: 2861 LPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAP-- 2918
Query: 1078 ASVQSVPTQTATLLPPANPPLPGGPGIASPC--------PTVQLTVEPVQEEQASQDKPP 1129
+ + + LPP P P P + + PT+ +E V +S +
Sbjct: 2919 ---EGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTEL-- 2973
Query: 1130 GLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRL 1189
G P G EL D + + +A E + L
Sbjct: 2974 GRPNPLALEAGKLPCEDPELDDDFD-------------------AHKALEDDEELAHLGL 3014
Query: 1190 TILNVCNTGDKMVECQ-LETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIE 1248
+ +V D++ + LET++ + L+GD D +A E D +++ F E
Sbjct: 3015 GV-DVAKGDDELGTLENLETNDPHLDDL---LNGDEFDLLAYTDPELD--TGDKKDIFNE 3068
Query: 1249 QMKDVMDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANA---PVYQQNV 1305
++ V E +E RG +PG P E R + P ++
Sbjct: 3069 HLRLVESANEK--AEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGG 3126
Query: 1306 LHTGKRWFIICPVAEHPAPEAPESSPPL-PLSSL--PPEASQDSAPYKDQLSSKEQPSFL 1362
H F I PAP A L P S+ + + P+ + E+ SF
Sbjct: 3127 RHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFG 3186
Query: 1363 ASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGT 1422
A+ G PPA L SP + P S++ E + PG
Sbjct: 3187 AT-------------GGPPAHLLTPSPL--------SGPGGSSLLEKFELESGALTLPGG 3225
Query: 1423 PQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEP 1482
P EL+ + E PL ++ L+ E + SA +P +
Sbjct: 3226 PAASGDELDKMESSLVASELPLLIEDLLE-----HEKKELQKKQQLSAQLQPAQQQQQQQ 3280
Query: 1483 SPHS--GTPQPALGQPAP---LLPAAVG-----AVSLATSQLPSPPLGPTVPPQPPS 1529
HS P PA P P+ G ++ LA ++ P P P +P QPP+
Sbjct: 3281 QQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLP-QPLMPTQPPA 3336
Score = 58.2 bits (139), Expect = 9e-08
Identities = 116/445 (26%), Positives = 147/445 (33%), Gaps = 68/445 (15%)
Query: 561 PDKARGPPVPLQVQVTYHAQAGQPG------PPEPE-EPEADQHLLPPTLPTSATSLASD 613
P P P + + AGQPG P P +P L P P S +LA
Sbjct: 2200 PSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCP-SLDNLAVP 2258
Query: 614 STFDSGQGSTV--------YSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQS 665
+ G G + +S+ + + V L ++PS PP P S
Sbjct: 2259 ESPGVGGGKASEPLLSPPPFGESRKALE-VKKEELGASSPS-----YGPPNLGFVDSPSS 2312
Query: 666 LPSLGAYQQPTA----APGLPVGSVPAPACPP-SLQQHFPDPAMSFAPVLPPPSTPMPTG 720
LG + T AP P S P P L+ P PA + AP PPS P
Sbjct: 2313 GTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAP--SPPSHPDIFR 2370
Query: 721 PGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 780
PG P QPP +P P P P+ L PP P P S+V PA +
Sbjct: 2371 PGSYTDPYAQPPLTPRPQPPP----PESCCAL---PPRSLP-SDPFSRV--PASPQSQSS 2420
Query: 781 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
Q+PL P P PV P PP+ P P PP+ P V
Sbjct: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQS-PDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAF 2479
Query: 841 PS--------LAAPLPPASPALPLQAVKLPHPPGAP---LAMPCRTIVPNAPATIPLLAV 889
+ A P A PA P + P G P + P P+ P+
Sbjct: 2480 KAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPS--PMRFT 2537
Query: 890 APPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDV---PPSPHHTVQNMRATPPQPALPP 946
P V S+ V Q PG P P P S ++TV P L P
Sbjct: 2538 FPQAVGEPSLKPPVPQ-PGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGP 2596
Query: 947 -----------QPTLPPQPVLPPQP 960
P PP + PP P
Sbjct: 2597 SSGSTGESYGLSPLRPPSVLPPPAP 2621
Score = 53.9 bits (128), Expect = 2e-06
Identities = 99/407 (24%), Positives = 143/407 (35%), Gaps = 69/407 (16%)
Query: 720 GPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQ 779
GPG PA P Q P L P ++ + P + A++ + Q PL
Sbjct: 3998 GPGMPAKP-------LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLA 4050
Query: 780 MPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVI 839
+ P + +A P ++ P L+G D V P P PQ
Sbjct: 4051 IGTTP-ESMATEPGEVKP--------SLSG---------DSQLLLVQPQPQPQ------- 4085
Query: 840 LPSLAAPLPPAS-PALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAP------- 891
PS PP P Q V L H G + + +++P L P
Sbjct: 4086 -PSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQ 4144
Query: 892 PGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP 951
PG ++ + +P+ PQ PP P +Q+ + P +P L
Sbjct: 4145 PGSMTQNLLGPQQPMLERPMQNNTGPQ------PPKPGPVLQSGQGLPGVGIMPTVGQLR 4198
Query: 952 PQ--PVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPV--LPPQPALPVRPEPLQP 1007
Q VL P L L PQ + Q +L + + Q V PP + PLQ
Sbjct: 4199 AQLQGVLAKNPQLRH---LSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQG 4255
Query: 1008 HLPEQAAPAATPGSQI-----LLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAA 1062
L Q PG Q L P P P +P PP A+ + P+ + P
Sbjct: 4256 LLGCQPQLGGFPGPQTGPLQELGAGPRPQGP------PRLPAPPGALSTGPVLGPVHPTP 4309
Query: 1063 PELLPQFPSSLATVSASVQSVPTQTATLLPPANP--PLPGGPGIASP 1107
P PQ P + + + +PT+ LPP +P P P GP + P
Sbjct: 4310 PPSSPQEPKRPSQLPSPSSQLPTEAQ--LPPTHPGTPKPQGPTLEPP 4354
Score = 53.1 bits (126), Expect = 3e-06
Identities = 46/140 (32%), Positives = 59/140 (42%), Gaps = 11/140 (7%)
Query: 667 PSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPS-TPMPTGPGQPA 725
P LG + P P +G+ P P PP L P A+S PVL P TP P+ P +P
Sbjct: 4261 PQLGGFPGPQTGPLQELGAGPRPQGPPRLPA--PPGALSTGPVLGPVHPTPPPSSPQEPK 4318
Query: 726 PPGQQPPPLAQ-PT----PLPQVLAPQPVVP-LQPVPPHLPPYLAPASQVGAPAQLKPLQ 779
P Q P P +Q PT P P+P P L+P P + P A + L P
Sbjct: 4319 RPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWD 4378
Query: 780 MPQAPLQPLAQVPPQMPPIP 799
P + Q P Q +P
Sbjct: 4379 PPDNLAE--TQKPEQSSLVP 4396
Score = 51.6 bits (122), Expect = 8e-06
Identities = 66/243 (27%), Positives = 84/243 (34%), Gaps = 45/243 (18%)
Query: 917 PQMAPTDVPPSPHHTVQNM----RATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQP 972
P PTD P + + Q T QP P +P+ L PQ P
Sbjct: 377 PGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNE 436
Query: 973 TRPPQPVLPPQPMLPP---QPVLPPQPA---------LPVRPEPLQPHL--PEQAAPAAT 1018
P P P+ PP P PP A LP P P HL P + +P +
Sbjct: 437 EMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSP 496
Query: 1019 PGSQILLGHP---APYA--------------VDVAAQVPTVPVPPAAVLSPPLPEVLLPA 1061
P + L P +P++ A + P P P A+ LSPP E L
Sbjct: 497 PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSP 556
Query: 1062 APELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEE 1121
PE LP P AS S P + + P +PP P SP P P +E
Sbjct: 557 PPEELPTSPPP----EASRLSPPPEES----PMSPPPEESP--MSPPPEASRLFPPFEES 606
Query: 1122 QAS 1124
S
Sbjct: 607 PLS 609
Score = 51.6 bits (122), Expect = 8e-06
Identities = 143/648 (22%), Positives = 215/648 (33%), Gaps = 120/648 (18%)
Query: 1322 PAPEAPESSPPLP---LSSLPPEASQDSAPYKDQLSSKEQPSFLASQ-QLLSQAGPSNPP 1377
P PE P SP LS P E + P + LS + + L+ Q + L + + P
Sbjct: 754 PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813
Query: 1378 GAPPAPLAPS---SPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQ 1434
P P P P + L P S PE + + P +P+ E Q
Sbjct: 814 HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873
Query: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLP-----PPAPEP--SPHSG 1487
A E PL P L+P P A + P PLP P+ EP SP
Sbjct: 874 CPAP-EELPLFPPPGEPSLSPLLGEP--ALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
Query: 1488 TPQPALGQPAPLLPAAVGAVSLATSQL-----------PSPPLGPTVPP-------QPPS 1529
P P P PL P A A S L S P P P PP
Sbjct: 931 PPDPL---PPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPE 987
Query: 1530 ALESDGEGPPPRV------GFVDSTIKSLDEKL---------RTLLYQEHVPTSSASAGT 1574
A +D E PP + V L E L +L+ Q P+ +
Sbjct: 988 ANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL 1047
Query: 1575 PVEVGDRDFTLEPLRGDQPRSEVCGGD---LALPPVPKEAVSGRVQLPQPLVEKSELAPT 1631
P+ V + + G +E+ + ++ P P S LP P+ + S AP+
Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107
Query: 1632 RGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDR 1691
++ S + +++P + G D G Q EP
Sbjct: 1108 PAPALDD--FSGLGEDTAP--LDGIDAPGSQ-----------------------PEPGQT 1140
Query: 1692 DGGEAGESSAEP---PPSDMGTVGGQASHPQTLGARALGSPRKRPEQ--QDVSSPAKTVG 1746
G A E P P ++ V +P+ GSP + E+ V+ T+
Sbjct: 1141 PGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLI 1200
Query: 1747 RFSVVS-----TQDEWTLASPHSLRYSAPPD------------VYLDEAPSSPDVKLAV- 1788
+ +V+ +Q + + + P S PD V D +P+ + L +
Sbjct: 1201 KSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLC 1260
Query: 1789 --RRAQTASSIEVGVGEPVSSD--SGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFL 1844
+T S+ G +S G++G R P + + S S G
Sbjct: 1261 TDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPG---------- 1310
Query: 1845 QRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDAD 1892
+R R G+ G R +K S+ + S + E ED D
Sbjct: 1311 RRRPRGGAHGGRGRGRARLKSTASSIETLVVADIDSSPSKEEEEEDDD 1358
Score = 50.8 bits (120), Expect = 1e-05
Identities = 113/474 (23%), Positives = 151/474 (31%), Gaps = 98/474 (20%)
Query: 1380 PPAPLAPSSPPVTALPQD--GAAPATSTMPEPASG----TASQAGGPGTPQGLTSELETS 1433
PP P A SPP A P G+ + + A G A GP +P L +L
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
Query: 1434 QPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSG-TPQPA 1492
P + P GLAP P T + P P P AP P G + +P
Sbjct: 2167 VPAQVPSQDPF-------GLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219
Query: 1493 LGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSAL-ESDGEG----------PPPR 1541
GQP G S P P L P P A+ ES G G PPP
Sbjct: 2220 AGQPGEFHTTPPGTPRHQPS-TPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP- 2277
Query: 1542 VGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGD 1601
F +S K+L+ K +E + SS S G P + F P G
Sbjct: 2278 --FGESR-KALEVK------KEELGASSPSYGPP----NLGFVDSPSSGTH--------- 2315
Query: 1602 LALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGR 1661
G ++L P V K+ L P V Q + + P +
Sbjct: 2316 -----------LGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQA------- 2357
Query: 1662 QVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTL 1721
+ PS P P RP TD +PPP + S P
Sbjct: 2358 -------LAPSPPSH-PDIFRPGSY--TDPYAQPPLTPRPQPPPPESCCALPPRSLPSDP 2407
Query: 1722 GARALGSPRK----------RPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPP 1771
+R SP+ RP + P+ RF Q + P S S P
Sbjct: 2408 FSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRF-----QSPDPYSRPPSRPQSRDP 2462
Query: 1772 DVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEG------PRARPP 1819
L + P ++A + A + G P + +G G P +PP
Sbjct: 2463 FAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPP 2516
Score = 48.5 bits (114), Expect = 7e-05
Identities = 112/426 (26%), Positives = 148/426 (34%), Gaps = 71/426 (16%)
Query: 620 QGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAP 679
Q T+ S Q QQ V LG A P S P + GP L L +Q T P
Sbjct: 3980 QSRTLLSPQQQQQQQVALGPGMPAKPLQH---FSSPGALGPTL-----LLTGKEQNTVDP 4031
Query: 680 GLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTP 739
+ + P S Q P A P S G +P+ G L QP P
Sbjct: 4032 AVSSEATEGP----STHQGGP-----LAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQP 4082
Query: 740 LPQV--LAPQPVVPLQPVPPHLPPYLAPAS-----QVGAPAQLKPLQMPQAPLQPLAQVP 792
PQ L QP + L L A Q+G+ + + +P QP +
Sbjct: 4083 QPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLG 4142
Query: 793 PQMPPIPVVPPITPLAGIDGLPPALPDLP----TATVPPVPPPQYFS----PAV-ILPS- 842
Q P + + G + + P T PP P P S P V I+P+
Sbjct: 4143 DQ--------PGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTV 4194
Query: 843 --LAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 900
L A L P P A+ + + + A PG +
Sbjct: 4195 GQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQ 4254
Query: 901 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQ-----PV 955
+ P +P PQ P +Q + A P +P PP+ PP PV
Sbjct: 4255 GLLGCQPQLGGFPG--PQTGP----------LQELGAGP-RPQGPPRLPAPPGALSTGPV 4301
Query: 956 LPPQPTLPPQPVLPPQPTRPPQPVLP-PQPMLPPQPVLPPQPALPVRPEPLQPHL---PE 1011
L P PP P P +P RP Q LP P LP + LP P P P+P P L P
Sbjct: 4302 LGPVHPTPP-PSSPQEPKRPSQ--LPSPSSQLPTEAQLP--PTHPGTPKPQGPTLEPPPG 4356
Query: 1012 QAAPAA 1017
+ +PAA
Sbjct: 4357 RVSPAA 4362
Score = 48.1 bits (113), Expect = 9e-05
Identities = 112/463 (24%), Positives = 157/463 (33%), Gaps = 95/463 (20%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQA---GP 1373
P+ P P PES LP SLP + SS + P L + L ++A P
Sbjct: 2382 PLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSP--LTPRPLSAEAFCPSP 2439
Query: 1374 -----------SNPPGAPPA--PLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGG- 1419
S PP P + P AP P P + A A S + T+ AGG
Sbjct: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGS-----LAHTSLGAGGF 2494
Query: 1420 -PGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPP 1478
P G EL P + + P V+ G TP+P T + L PP
Sbjct: 2495 PAALPAGPAGELHAKVP---SGQPPNFVRSPGTGAFVGTPSP-MRFTFPQAVGEPSLKPP 2550
Query: 1479 APEPS---PHSGT----PQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPT--------- 1522
P+P PH P P LG+P + V+ PLGP+
Sbjct: 2551 VPQPGLPPPHGINSHFGPGPTLGKP----QSTNYTVATGNFHPSGSPLGPSSGSTGESYG 2606
Query: 1523 -VPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDR 1581
P +PPS L PPP +L Y H + + +PVE +
Sbjct: 2607 LSPLRPPSVL------PPPAPD-------------GSLPYLSHGASQRSGITSPVEKRE- 2646
Query: 1582 DFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTS 1641
+P G G LA +P G L Q +EK Q
Sbjct: 2647 ----DPGTG-------MGSSLATAELPGTQDPGMSGLSQTELEKQR--------QRQRLR 2687
Query: 1642 SSMTAESSPRSMLGYDRDGRQVASDSHVVP---SVPQDVPAFVRPARVEPTDRDGGEAGE 1698
+ + R+ L +++ A+ + P PAF + +R + T G +
Sbjct: 2688 ELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQ-TPFAGTQDKS 2746
Query: 1699 SSAEPPPSDM-GTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1740
S PPS + G + G S P + P P DV+S
Sbjct: 2747 SLVGLPPSKLSGPILGPGSFPSD-DRLSRPPPPATPSSMDVNS 2788
Score = 47.8 bits (112), Expect = 1e-04
Identities = 63/237 (26%), Positives = 85/237 (35%), Gaps = 36/237 (15%)
Query: 1336 SSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALP 1395
SS+P +Q S DQ S Q Q +L + +N PP P P LP
Sbjct: 4128 SSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKP-GPVLQSGQGLP 4186
Query: 1396 QDGAAPATSTMPEPASGTASQAG-----GPGTPQGLTS-----ELETSQPLAET--HEAP 1443
G P + G ++ P Q L + +L+ SQ + +T ++ P
Sbjct: 4187 GVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEP 4246
Query: 1444 LAVQPLVVGLAPCTP------APEA-------ASTRDASAPREPLPPPAPEPSPHSGTPQ 1490
+ GL C P P+ A R PR P PP A P G
Sbjct: 4247 GTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVH 4306
Query: 1491 PALGQPAPLLPAAVGAVSLATSQLPS----PPLGPTVP-PQPPSALESDGEGPPPRV 1542
P +P P + +SQLP+ PP P P PQ P+ E PP RV
Sbjct: 4307 PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL-----EPPPGRV 4358
Score = 46.2 bits (108), Expect = 4e-04
Identities = 70/276 (25%), Positives = 93/276 (33%), Gaps = 40/276 (14%)
Query: 1271 SDPGTSPPHL-STCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329
S +S PHL + + G++ N QQ +L P+ + P+ P+
Sbjct: 4124 SSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLER--------PMQNNTGPQPPKP 4175
Query: 1330 SPPL------PLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQ------LL-------SQ 1370
P L P + P Q A + L+ Q L+ QQ LL SQ
Sbjct: 4176 GPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQ 4235
Query: 1371 AGPSNPPGAPPAP-LAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSE 1429
A PP P +P + PQ G P T P G + GP
Sbjct: 4236 AVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295
Query: 1430 LETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTP 1489
L T L H P P P+P + +A P P P P+P + P
Sbjct: 4296 LSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP--PTHPGTPKPQGPTLEP 4353
Query: 1490 QPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPP 1525
P PA A LA + L S LGP PP
Sbjct: 4354 PPGRVSPA--------AAQLADT-LFSKGLGPWDPP 4380
Score = 43.5 bits (101), Expect = 0.002
Identities = 81/348 (23%), Positives = 119/348 (34%), Gaps = 38/348 (10%)
Query: 548 PALQPKEQQDVGSPDKARGPP----VPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTL 603
P L P+ ++ P + P P + + G+P EP EP LP L
Sbjct: 858 PPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP--LPEEL 915
Query: 604 PTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLP 663
P S + S S + D S ++ + A A SP + P ++G P
Sbjct: 916 PLSPSGEPSLSP------QLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDP 969
Query: 664 QSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQ 723
+S + + P + P + P P P L P +P+L P P + Q
Sbjct: 970 ESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQ 1029
Query: 724 PA-PPGQQPPPLAQPTPLPQVLAPQPVVPLQPV----------PPHLPPYLAPASQVGAP 772
+ P PP P LP + P P+ P+ V P P
Sbjct: 1030 HSLVPQNSPPSQCSPPALP-LSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEP 1088
Query: 773 AQLKPLQMPQAPLQ-PLAQVPPQMPPIPVVPPIT-PLAGIDGLPPALPDLPTATVPPVPP 830
+ PL P L P P + + T PL GID P + P+ P T +
Sbjct: 1089 SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDA-PGSQPE-PGQTPGSLAS 1146
Query: 831 PQYFSPAVILPSLAAPLPP----------ASPALPLQAVKLPHPPGAP 868
SP ++ P AP+ P A P + + P P AP
Sbjct: 1147 ELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP 1194
Score = 43.5 bits (101), Expect = 0.002
Identities = 67/260 (25%), Positives = 89/260 (34%), Gaps = 44/260 (16%)
Query: 1319 AEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP----S 1374
A+ P+ + +P PL P A PY + QP L + P +
Sbjct: 2169 AQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHT 2228
Query: 1375 NPPGAP------PAP-LAPSSPPV--TALPQD----GAAPATSTMPEPASGTASQA---- 1417
PPG P P P L P P + A+P+ G + + P G + +A
Sbjct: 2229 TPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVK 2288
Query: 1418 ----GGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAP---EAASTRDASA 1470
G G + P + TH L ++ V AP TP E S
Sbjct: 2289 KEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLR 2348
Query: 1471 PREPLPPPAPEPSPHSGT------------PQPALGQPAPLLPAAVGAVSLATSQLPSPP 1518
P+EP P A PSP S QP L P P P +L LPS P
Sbjct: 2349 PQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL-TPRPQPPPPESCCALPPRSLPSDP 2407
Query: 1519 LGPTVPPQPPSALESDGEGP 1538
VP P S +S + P
Sbjct: 2408 FS-RVPASPQS--QSSSQSP 2424
Score = 43.5 bits (101), Expect = 0.002
Identities = 101/399 (25%), Positives = 153/399 (38%), Gaps = 57/399 (14%)
Query: 1366 QLLSQAGPSNPPGAPPAPLAPSSPP-VTALPQDGAAPATSTMPEPASGTASQAGGPGTPQ 1424
QLL++ SNPP PP+ L P+ PP V +G P+ P +++
Sbjct: 4609 QLLTKNNLSNPP-TPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRD 4667
Query: 1425 GLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSP 1484
TSE+++ LA P Q V + + S AS+P L AP P
Sbjct: 4668 --TSEVKSLDLLAAL-PTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPR-FP 4723
Query: 1485 HSGT-----PQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP 1539
H G+ AL PL+P A ++ + P LG VP + P G+G
Sbjct: 4724 HLGSGRWEQEDRALSPVIPLIPRA--SIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSE 4781
Query: 1540 PRV-------------GFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLE 1586
V G + + + L K+ Y+ P S A AGT + G+ +
Sbjct: 4782 VSVMLTVSAAAAKNLNGVMVAVAELLSMKIPN-SYEVLFPESPARAGTEPKKGEAEGPGG 4840
Query: 1587 PLRGDQPRSEVCGGDLAL---PPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSS 1643
+G + +S G D +P + ++ + L ++S AP E T S
Sbjct: 4841 KEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESP-AP------EPPTQHS 4893
Query: 1644 MTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGE-AGESSAE 1702
T S + D RQ+++ PS P P+ + P+ P E E AE
Sbjct: 4894 YTYNVS-------NLDVRQLSAPPPEEPSPP---PSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 1703 PP-PSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1740
PP PS + AS P++ A PR RP ++ S
Sbjct: 4944 PPVPSPLPL----ASSPES----ARPKPRARPPEEGEDS 4974
Score = 42.7 bits (99), Expect = 0.004
Identities = 28/100 (28%), Positives = 38/100 (38%), Gaps = 11/100 (11%)
Query: 918 QMAPTDVPPSPHH--------TVQNMRATPPQPALPPQPTLPPQPVLPPQP---TLPPQP 966
Q +P PP+ H V+ + A PP+ PP L P P PP LP +P
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEP 4940
Query: 967 VLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQ 1006
+ P P P+ P PP+ RP L+
Sbjct: 4941 LAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980
Score = 38.5 bits (88), Expect = 0.074
Identities = 39/135 (28%), Positives = 57/135 (42%), Gaps = 14/135 (10%)
Query: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQA-GPSNPPGAP 1380
PA + + L S P A S P++ PS SQQ LS + PG P
Sbjct: 3272 PAQQQQQQQQQHSLLSAPGPAQAMSLPHEGS-----SPSLAGSQQQLSLGLAGARQPGLP 3326
Query: 1381 PAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETH 1440
PL P+ PP AL Q AP+ + + + Q GG GL + ++SQP+
Sbjct: 3327 Q-PLMPTQPPAHAL-QQRLAPSMAMVSNQGHMLSGQHGGQA---GLVPQ-QSSQPVLS-- 3378
Query: 1441 EAPLAVQPLVVGLAP 1455
+ P+ P + + P
Sbjct: 3379 QKPMGTMPPSMCMKP 3393
Score = 37.7 bits (86), Expect = 0.13
Identities = 71/313 (22%), Positives = 93/313 (29%), Gaps = 67/313 (21%)
Query: 1273 PGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPP 1332
P T PP+ S G + + Q HT P P P
Sbjct: 2193 PPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHT-------------TPPGTPRHQPS 2239
Query: 1333 LPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVT 1392
P L P P D L+ E P G ++ P P P S +
Sbjct: 2240 TPDPFLKPRC-----PSLDNLAVPESPGV--------GGGKASEPLLSPPPFGESRKALE 2286
Query: 1393 ALPQDGAAPATSTMP-------EPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLA 1445
++ A + S P P+SGT TP + L E L
Sbjct: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLG 2346
Query: 1446 VQPL----VVGLAPCTPA------PEAASTRDASAPREPLPPPAPEPS-----PHS---- 1486
++P LAP P+ P + + A P P P P P S P S
Sbjct: 2347 LRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSD 2406
Query: 1487 ------GTPQPALGQPAPLLPAAVGAVSLATS------QLPSPPLGPTVPPQ---PPSAL 1531
+PQ +PL P + A + S Q P P P PQ P + L
Sbjct: 2407 PFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPL 2466
Query: 1532 ESDGEGPPPRVGF 1544
PP V F
Sbjct: 2467 HKPPRPQPPEVAF 2479
Score = 36.6 bits (83), Expect = 0.28
Identities = 41/155 (26%), Positives = 55/155 (35%), Gaps = 15/155 (9%)
Query: 1325 EAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPL 1384
+A +PP Q + QL P Q+L + P PP P P
Sbjct: 4235 QAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPG 4294
Query: 1385 APSSPPV---------TALPQDGAAPATSTMPEPASGTASQA----GGPGTPQGLTSELE 1431
A S+ PV + PQ+ P S +P P+S ++A PGTP+ LE
Sbjct: 4295 ALSTGPVLGPVHPTPPPSSPQEPKRP--SQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLE 4352
Query: 1432 TSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTR 1466
A LA GL P P A T+
Sbjct: 4353 PPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387
Score = 36.2 bits (82), Expect = 0.37
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 11/72 (15%)
Query: 785 LQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALP--DLPTATV--PPVPPPQYFSPAVIL 840
++ L+ PP+ P PP +PLA PP P +LPT + PPVP P P
Sbjct: 4903 VRQLSAPPPEEPS----PPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSP---LPLASS 4955
Query: 841 PSLAAPLPPASP 852
P A P P A P
Sbjct: 4956 PESARPKPRARP 4967
Score = 35.4 bits (80), Expect = 0.63
Identities = 26/77 (33%), Positives = 31/77 (40%), Gaps = 3/77 (3%)
Query: 742 QVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQ-PLAQVPPQMPPIPV 800
Q+ AP P P P P P +P ++ +PL P P PLA P P P
Sbjct: 4905 QLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Query: 801 VPPITPLAGIDGLPPAL 817
P P G D PP L
Sbjct: 4965 ARP--PEEGEDSRPPRL 4979
Score = 34.3 bits (77), Expect = 1.4
Identities = 75/350 (21%), Positives = 112/350 (32%), Gaps = 47/350 (13%)
Query: 700 PDPAMSFAPVLPPPSTP--MPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVP------ 751
P P S P PPPS M G G+ P A + L V
Sbjct: 4620 PTPPSSLPPT-PPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLA 4678
Query: 752 LQPVPPHLPPY---LAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLA 808
P PPH + +P + P P++ L A P P +
Sbjct: 4679 ALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEA------PRFPHLGSGRWEQ 4732
Query: 809 GIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPP--------ASPALPLQAVK 860
L P +P +P A++P P + + + P+ S L + A
Sbjct: 4733 EDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAA 4792
Query: 861 LPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQ----------- 909
+ G +A+ + P + +L P A A+ PG
Sbjct: 4793 AKNLNGVMVAV-AELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPD 4851
Query: 910 --PVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQP--TLPPQPVLPPQPTLPPQ 965
P + F + P S + ++ P P P Q T + Q + PP
Sbjct: 4852 TGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP- 4910
Query: 966 PVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAP 1015
P +P+ PP P L P P PP L P P+ P+ LP ++P
Sbjct: 4911 ---PEEPSPPPSP-LAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSP 4956
Score = 33.9 bits (76), Expect = 1.8
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 725 APPGQQP-PPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQA 783
APP ++P PP + P P +P+V L P PP +P +P +P +
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967
Query: 784 PLQPLAQVPPQM 795
P + PP++
Sbjct: 4968 PEEGEDSRPPRL 4979
Score = 32.7 bits (73), Expect = 4.1
Identities = 54/212 (25%), Positives = 69/212 (32%), Gaps = 24/212 (11%)
Query: 584 PGPPEPEEPEADQ---HLLPPTLPTSATSLASDSTFD---SGQGSTVYSDSQSSQQSVML 637
PG P E D+ L+ LP L + Q S +Q QQ
Sbjct: 3223 PGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQ 3282
Query: 638 GSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQ 697
SL +AP PAQ + P P L S L PGLP +P +LQQ
Sbjct: 3283 HSLL-SAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQ 3341
Query: 698 HFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPP 757
PS M + G GQ Q +PQ + QPV+ +P+
Sbjct: 3342 RL------------APSMAMVSNQGHML-SGQHG---GQAGLVPQ-QSSQPVLSQKPMGT 3384
Query: 758 HLPPYLAPASQVGAPAQLKPLQMPQAPLQPLA 789
P Q+ QL P L A
Sbjct: 3385 MPPSMCMKPQQLAMQQQLANSFFPDTDLDKFA 3416
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 121 bits (304), Expect = 7e-27
Identities = 160/571 (28%), Positives = 202/571 (35%), Gaps = 151/571 (26%)
Query: 640 LADAAP-SPAQCVCSP---------PVSEGPVL---------------PQSLPSLGAYQQ 674
LA AAP + Q + +P P+S GPVL P + +Q
Sbjct: 498 LAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQM 557
Query: 675 PT--AAPGLPVGSVPAPA------------CPPSLQQHFPDPAMSFAPVLPPPST--PMP 718
P AA LP S PAPA PPS P P P +T P
Sbjct: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAP 617
Query: 719 TGPGQPAPPGQQPPPLAQPTPL----------PQVLAPQPVVPLQPVPPHLPPYLAPASQ 768
QPAP Q PP ++ P PL PQ PQ P Q P P LA + +
Sbjct: 618 VLTVQPAP--QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPE 675
Query: 769 ---VGAPAQLKP--------LQM---PQAPLQPLAQVPPQM-----------PPIPVVPP 803
+G P P LQM + QPL+ P + PP P
Sbjct: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAP 735
Query: 804 ITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQA----- 858
TP+A GL P PD + P P PQ + A L P P +SP+LP QA
Sbjct: 736 ATPVAKGAGLGPQAPD---SQASPAPAPQIPAAA----PLKGPGPSSSPSLPHQAPLGDS 788
Query: 859 --VKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAF 916
+ PHP P P R + P + P L PP A ++ + + Q P
Sbjct: 789 PHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTL-PGIFVIQNQLGVPPPA 847
Query: 917 PQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLP------------PQPT--- 961
APT P P ++ PP+ LPP P LPP P PT
Sbjct: 848 SNPAPT--APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905
Query: 962 ----LPPQPVLPPQPTRPPQPVLPPQPMLPPQP-------VLPPQPALPVRPE------- 1003
PP PT PP L P+P PP P V P PALP +P+
Sbjct: 906 FQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALP-QPKALLERFH 964
Query: 1004 ---------------PLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAA 1048
P P P +P + +L+ AP A P P AA
Sbjct: 965 QVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAA 1024
Query: 1049 VLSPPLPEVLLPAAPELLPQFPSSLATVSAS 1079
PP LLPA + F S+L T++ +
Sbjct: 1025 TGLPP----LLPAENK---AFASNLPTLNVA 1048
Score = 120 bits (300), Expect = 2e-26
Identities = 174/629 (27%), Positives = 218/629 (34%), Gaps = 92/629 (14%)
Query: 567 PPVPLQVQVTYHAQAGQ----PGPPEP--------EEPEADQHLLPPTLPTSATSLASDS 614
P P + +AGQ G P P + P PP P + + S
Sbjct: 391 PKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVH 450
Query: 615 TFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAY-- 672
+ G + + Q+ L A A P Q P G +L + P G
Sbjct: 451 LLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLI 510
Query: 673 ------QQPTAAPGLPVGSVPAP-----------ACPPSLQQH--FPDPAMSFAPVLPPP 713
Q A P L +G V AP A P + Q F P A LP
Sbjct: 511 ANPILTNQNLAGP-LSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQ 569
Query: 714 STPMPTGP-------GQPAPPG-----QQPPPLAQP-TPLPQVLAPQPVVPLQPVPPHLP 760
S P P GP G PP P L QP TP PV+ +QP P P
Sbjct: 570 SQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAP-QAP 628
Query: 761 PYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMP-----------PIPVV----PPIT 805
P ++ +G Q + Q PQAP P A PPQ P +V P T
Sbjct: 629 PAVSTPLPLGLQ-QPQAQQPPQAPT-PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSAT 686
Query: 806 PLAGI--DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPH 863
P A + D L LP + P PA ++ S P +PA P+ A
Sbjct: 687 PTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV-AKGAGL 745
Query: 864 PPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTD 923
P AP + P PA PL P +L A L P P+ P P+
Sbjct: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQ---APLGDSPHLPSPHPTRPPSR 802
Query: 924 VPPSPHHTVQNMRATPPQPALPPQ--PTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLP 981
P P + P P PPQ PTLP V+ Q +PP P P PT P
Sbjct: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP-PASNPAPTAPG----- 856
Query: 982 PQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGH-PAPYAVDVAAQVP 1040
PPQP L PQ P P P PHLP + +A S PAP D Q P
Sbjct: 857 -----PPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP 911
Query: 1041 TVPVPPAAVLSPP-LPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATL----LPPAN 1095
P + PP L V PAAP P P + V+ ++P A L P+
Sbjct: 912 PSQGPHKSPTPPPTLHLVPEPAAPP--PPPPRTFQMVTTPFPALPQPKALLERFHQVPSG 969
Query: 1096 PPLPGGPGIASPCPTVQLTVEPVQEEQAS 1124
L G A P ++ P+ AS
Sbjct: 970 IILQNKAGGAPAAPQTSTSLGPLTSPAAS 998
Score = 107 bits (268), Expect = 1e-22
Identities = 162/578 (28%), Positives = 226/578 (39%), Gaps = 90/578 (15%)
Query: 631 SQQSVMLGSLADAA-PSPAQCVCSPPVSE---GPVLPQSLPSLGAYQQPTAAPGLPVGSV 686
++Q + G LA AA PS + S VS G V+ ++L + A + G+
Sbjct: 254 AKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAA 313
Query: 687 PAPACPPSLQQHFPDPAMSFAPVLPPPSTPM---PTGPGQPAPPGQQPPPLAQPTPLP-- 741
AP PS Q P + +P++P P+ + PT P QP P G PP L Q TP P
Sbjct: 314 SAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPT-PIQPKPAGVLPPKLYQLTPKPFA 372
Query: 742 ------QVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMP--------QAPLQP 787
+ +P QP P ++A A + G L P Q P
Sbjct: 373 PAGATLTIQGEPGALPQQPKAPQNLTFMA-AGKAGQNVVLSGFPAPALQANVFKQPPATT 431
Query: 788 LAQVPPQMPPIPVVPPITPL--AGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAA 845
PPQ P P L G + PA LP +P +PAV LP +
Sbjct: 432 TGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPG----APAVQLPQQLS 487
Query: 846 PLPPASPALPLQAVKLPHPPGAPLAMPCRT-------------IVPNAPA-TIPLLAVAP 891
L PA+ + A PH G +A P T + P++ A + +L+ AP
Sbjct: 488 AL-PANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAP 546
Query: 892 -----PGVAALSIHSAVAQLPGQ----PVYPAAFPQMAPTDVPPSPHHTVQNMRATPP-- 940
P + + + A LP Q P PAA + +PPS M TP
Sbjct: 547 IQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS----AVAMLNTPDGL 602
Query: 941 -QPALP--------PQPTLPPQPVLPPQPTLP-PQPVLPPQPTRPPQPVLPPQPMLPPQP 990
QPA P P T+ P P PP + P P + PQ +PPQ PQ PPQ
Sbjct: 603 VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ-APTPQAAAPPQA 661
Query: 991 VLP-PQPALPVRPEPLQPHLPEQAAPAA--TPGSQILLGHPAPYAVDVAAQVPTVPVPPA 1047
P P P L PE + P A P A T S + ++A+ P + VP +
Sbjct: 662 TTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPAS 721
Query: 1048 AVLS-PPLPEVLLPAAP-----ELLPQFPSSLATVSASVQ-------SVPTQTATLLPPA 1094
++S PP + PA P L PQ P S A+ + + Q P +++ P
Sbjct: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
Query: 1095 NPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
PL P + SP PT + P + + S +PP P
Sbjct: 782 QAPLGDSPHLPSPHPTRPPSRPPSRPQSVS--RPPSEP 817
Score = 61.6 bits (148), Expect = 8e-09
Identities = 86/319 (26%), Positives = 107/319 (33%), Gaps = 65/319 (20%)
Query: 1276 SPPHLST-CGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAP-ESSPPL 1333
+PP +ST LG + Q AP Q P A P P SSP
Sbjct: 627 APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAP----------PQATTPQPSPGLASSPEK 676
Query: 1334 PLSSLPPEASQDSAPYKDQLSSKEQPSFLA---SQQLLSQAGP-----------SNPPGA 1379
+ PP A+ + +D L FL SQQ LS GP + PP
Sbjct: 677 IVLGQPPSATPTAILTQDSLQM-----FLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
Query: 1380 PPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPG----------TPQGLTSE 1429
PAP P + PQ + A S P P A+ GPG P G +
Sbjct: 732 DPAPATPVAKGAGLGPQAPDSQA-SPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPH 790
Query: 1430 LETSQPLAETHEAPLAVQ-----PLVVGLAPCTP------------------APEAASTR 1466
L + P P Q P L PC P P AS
Sbjct: 791 LPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNP 850
Query: 1467 DASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQ 1526
+AP P PP P+ P G PA P +AV + S +S+LP+P
Sbjct: 851 APTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQF 910
Query: 1527 PPSALESDGEGPPPRVGFV 1545
PPS PPP + V
Sbjct: 911 PPSQGPHKSPTPPPTLHLV 929
Score = 59.7 bits (143), Expect = 3e-08
Identities = 70/231 (30%), Positives = 88/231 (38%), Gaps = 33/231 (14%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEA-SQDSAPYKDQLSSKEQPSFL---ASQQLLSQAG 1372
P PAP P ++ L +LPP A + + P D L P+ A+ L Q
Sbjct: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTP--DGLVQPATPAAATGEAAPVLTVQPA 624
Query: 1373 PSNPPG-APPAPLAPSSPPVTALPQ----DGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427
P PP + P PL P PQ AAP +T P+P+ G AS
Sbjct: 625 PQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASS----------P 674
Query: 1428 SELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSG 1487
++ QP + T A L L + L P+ S + SA L PA S
Sbjct: 675 EKIVLGQPPSATPTAILTQDSLQMFL------PQERSQQPLSAEGPHLSVPA---SVIVS 725
Query: 1488 TPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGP 1538
P PA PAP P A GA Q P P PQ P+A G GP
Sbjct: 726 APPPA-QDPAPATPVAKGAG--LGPQAPDSQASPAPAPQIPAAAPLKGPGP 773
Score = 55.1 bits (131), Expect = 8e-07
Identities = 57/196 (29%), Positives = 74/196 (37%), Gaps = 19/196 (9%)
Query: 1352 QLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPAS 1411
QL +K+ P S L S AGPS P A ++P + AA AT+
Sbjct: 251 QLLAKQVP---VSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVF 307
Query: 1412 GTASQAGGP-GTPQ--------GLTSELETSQPLAETHEAPLAVQPLVVGLAP-----CT 1457
G A A P GTP GL S P H P +QP G+ P T
Sbjct: 308 GGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLT 367
Query: 1458 PAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSP 1517
P P A + + EP P +P + T A ++ + A +L + P
Sbjct: 368 PKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQP 427
Query: 1518 PLGPT--VPPQPPSAL 1531
P T PPQPP AL
Sbjct: 428 PATTTGAAPPQPPGAL 443
Score = 55.1 bits (131), Expect = 8e-07
Identities = 66/238 (27%), Positives = 87/238 (36%), Gaps = 36/238 (15%)
Query: 1317 PVAEHPAPEAPESSPPL-PLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP-S 1374
P P P P S PP P S P + P + P Q L P S
Sbjct: 789 PHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPAS 848
Query: 1375 NP----PGAPPAPLAPSS-PPVTALPQDGAAPATSTMPEPASGTASQAGGPG-TPQGLTS 1428
NP PG P PL P S PP LP P +ST AS + + + P TP
Sbjct: 849 NPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQL 908
Query: 1429 ELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGT 1488
+ SQ H++P TP P + +AP PPP P T
Sbjct: 909 QFPPSQG---PHKSP-------------TPPPTLHLVPEPAAP----PPPPPRTFQMVTT 948
Query: 1489 PQPALGQPAPLL------PAAVGAVSLATSQLPSPPLGPTVPP--QPPSALESDGEGP 1538
P PAL QP LL P+ + + A +P ++ P P +++ G+ P
Sbjct: 949 PFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAP 1006
Score = 48.1 bits (113), Expect = 9e-05
Identities = 65/245 (26%), Positives = 84/245 (34%), Gaps = 48/245 (19%)
Query: 1317 PVAEHPAPEAP-ESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSN 1375
P A +PAP AP PPL S PPE AP+ PS +S S S
Sbjct: 845 PPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLP-------PSSTSSAVASSSETSSR 897
Query: 1376 PPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETS-- 1433
P P+ PP P S P P + P P T ++ T+
Sbjct: 898 LPAPTPSDFQLQFPP-------SQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
Query: 1434 ----QP---LAETHEAPL------------AVQPLVVGLAPCT-PAPEAASTRDASAPRE 1473
QP L H+ P A L P T PA + A +
Sbjct: 951 PALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTP 1010
Query: 1474 PLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVP--PQPPSAL 1531
P AP P+P + T P PLLPA A + S LP+ + P PS L
Sbjct: 1011 TAPSHAPAPAPMAATGLP------PLLPAENKAFA---SNLPTLNVAKAASSGPGKPSGL 1061
Query: 1532 ESDGE 1536
+ + +
Sbjct: 1062 QYESK 1066
Score = 45.8 bits (107), Expect = 5e-04
Identities = 110/464 (23%), Positives = 155/464 (33%), Gaps = 66/464 (14%)
Query: 1334 PLSSLPPEASQDSAPYKDQLSSKE----QPSFLASQQLLSQAGPSNPPGAPPAPLAPSSP 1389
PLS P A A LS+ QP+ Q +S A S P + PAP P++
Sbjct: 523 PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALF--QMPVSLAAGSLPTQSQPAPAGPAA- 579
Query: 1390 PVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQ-P 1448
T L P+ M G P TP T E + +AP AV P
Sbjct: 580 -TTVLQGVTLPPSAVAMLNTPDGLVQ----PATPAAATGEAAPVLTVQPAPQAPPAVSTP 634
Query: 1449 LVVGLAP--CTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGA 1506
L +GL P+A + + A+ P+ P P+P + S + LGQP P A+
Sbjct: 635 LPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLA--SSPEKIVLGQPPSATPTAILT 692
Query: 1507 -------VSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTL 1559
+ SQ P GP + P S + S PPP +T + L
Sbjct: 693 QDSLQMFLPQERSQQPLSAEGPHL-SVPASVIVS---APPPAQDPAPATPVAKGAGL--- 745
Query: 1560 LYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSG-RVQL 1618
P S AS ++ PL+G P S P +P +A G L
Sbjct: 746 --GPQAPDSQASPAPAPQIP----AAAPLKGPGPSSS--------PSLPHQAPLGDSPHL 791
Query: 1619 PQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVP 1678
P P + P S P G V + VP P P
Sbjct: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP-PASNP 850
Query: 1679 AFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDV 1738
A P +P R + E P P P + + A+ S + +
Sbjct: 851 APTAPGPPQPPLRPQSQPPEGPLPPAP----------HLPPSSTSSAVASSSETSSR--- 897
Query: 1739 SSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSP 1782
PA T F + + SP + PP ++L P++P
Sbjct: 898 -LPAPTPSDFQLQFPPSQGPHKSP-----TPPPTLHLVPEPAAP 935
Score = 40.8 bits (94), Expect = 0.015
Identities = 32/101 (31%), Positives = 39/101 (38%), Gaps = 13/101 (12%)
Query: 943 ALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT--------RPPQPVLPPQPMLPPQPVLPP 994
AL P PP P PP+P PP PT PP P P P P
Sbjct: 1326 ALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPP----PAAPERKPLGTAPH 1381
Query: 995 QPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDV 1035
P LP+R + + ++ AP TP + G PAP V
Sbjct: 1382 CPRLPLR-KTYRENVGGPGAPEGTPAGRARGGSPAPLPAKV 1421
Score = 36.2 bits (82), Expect = 0.37
Identities = 45/186 (24%), Positives = 68/186 (36%), Gaps = 22/186 (11%)
Query: 568 PVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLP----PTLPTSATSLASDSTFDS-GQGS 622
P P Q+ + G P + P HL+P P P T + F + Q
Sbjct: 901 PTPSDFQLQFPPSQG---PHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPK 957
Query: 623 TVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLP 682
+ ++L + A AP+ Q S GP+ + L + Q P+ P P
Sbjct: 958 ALLERFHQVPSGIILQNKAGGAPAAPQT----STSLGPLTSPAASVLVSGQAPSGTPTAP 1013
Query: 683 VGS-VPAPACPPSLQQHFPDPAMSFAPVLPP--PSTPMPTGPGQPAP-------PGQQPP 732
+ PAP L P +FA LP + +GPG+P+ G + P
Sbjct: 1014 SHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKP 1073
Query: 733 PLAQPT 738
P QP+
Sbjct: 1074 PTLQPS 1079
Score = 35.4 bits (80), Expect = 0.63
Identities = 43/142 (30%), Positives = 57/142 (40%), Gaps = 33/142 (23%)
Query: 1322 PAPEAPESSPP-------LPLSSLP-PEASQD----------------SAPYKDQLSSKE 1357
P P AP PP P +LP P+A + AP Q S+
Sbjct: 930 PEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989
Query: 1358 QP-SFLASQQLLSQAGPSNPPGAP-----PAPLAPSSPPVTALPQDGAAPATSTMPEPAS 1411
P + A+ L+S PS P AP PAP+A + P LP + A A++ +
Sbjct: 990 GPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLP-PLLPAENKAFASNLPTLNVA 1048
Query: 1412 GTASQAGGPGTPQGLTSELETS 1433
AS GPG P GL E + S
Sbjct: 1049 KAAS--SGPGKPSGLQYESKLS 1068
Score = 35.0 bits (79), Expect = 0.82
Identities = 52/204 (25%), Positives = 70/204 (34%), Gaps = 22/204 (10%)
Query: 921 PTDVPPSPHHTVQNMRATPPQPALPPQPT----------LPPQPVLPPQPTLPPQPVLPP 970
P PP P T++ + PP+P PP PT P P P T P P LP
Sbjct: 1329 PVHQPPPPPATLK-VAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPL 1387
Query: 971 QPTRPPQPVLPPQPM-LPPQPVLPPQPA-LPVRPEPLQPHLPEQAAPAATPGSQILLGHP 1028
+ T P P P PA LP + + L + A Q +L P
Sbjct: 1388 RKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447
Query: 1029 APYAVDVAAQVPTVP------VPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQS 1082
P AAQ P +PPA P+V + PQ + + +++ S
Sbjct: 1448 PPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDS 1507
Query: 1083 VPTQTATLLPPANPPLPGGPGIAS 1106
+ P P P P AS
Sbjct: 1508 ILNLQQA---PGRTPAPSYPHAAS 1528
Score = 34.3 bits (77), Expect = 1.4
Identities = 86/402 (21%), Positives = 126/402 (31%), Gaps = 45/402 (11%)
Query: 1351 DQLSSKEQPSFLASQQLLSQAGP------SNPPGAPPAPLAPSSPPVTALPQDGAAPATS 1404
D++ +E+ + LA + L++ P S G P A + P +AP S
Sbjct: 1176 DRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGAS 1235
Query: 1405 TMPEPASGT--ASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVV---GLAPCTPA 1459
T P P T + GG G +T S L+ + + A L G P
Sbjct: 1236 TQPPPHLPTKLVIRHGGAGGSPSVTWA-RASSSLSSSSSSSSAASSLDADEDGPMPSRNR 1294
Query: 1460 P--EAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSP 1517
P + R + + A T + QP P AT ++ P
Sbjct: 1295 PPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPP---------PPATLKVAEP 1345
Query: 1518 PLGPTVPPQPPSALESDGEGPPPRVGFVD--STIKSLDEKLRTLLYQEHVPTSSASAGTP 1575
P P PP P + + PPP T Y+E+V A GTP
Sbjct: 1346 PPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTP 1405
Query: 1576 VEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAV 1635
RG P D A + +E + +L Q +++ P A
Sbjct: 1406 A---------GRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAA 1456
Query: 1636 MEQGTSSSMTAESSP---RSMLGYDRDGRQVASDS--------HVVPSVPQDVPAFVRPA 1684
G P R D D +SDS H+ ++ + P
Sbjct: 1457 QGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPG 1516
Query: 1685 RVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARAL 1726
R + + A PPP +SH LGAR L
Sbjct: 1517 RTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGARTL 1558
Score = 33.9 bits (76), Expect = 1.8
Identities = 66/267 (24%), Positives = 91/267 (34%), Gaps = 45/267 (16%)
Query: 1334 PLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTA 1393
PLSS P AS P+ P+ L + + PS + L+ SS +A
Sbjct: 1226 PLSSSAPGASTQPPPHL--------PTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSA 1277
Query: 1394 LP-----QDGAAPATSTMPEPASGTASQAGGP---GTPQGLTSELETSQPLAETHEAPLA 1445
+DG P+ + P S+ G GL S++ + L H+ P
Sbjct: 1278 ASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGL-SKVVHNTALDPVHQPPPP 1336
Query: 1446 VQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVG 1505
L V P P P T + + PP APE P P P LP
Sbjct: 1337 PATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPH------CPRLP---- 1386
Query: 1506 AVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTL---LYQ 1562
GP P P+ + G P P VD L +L + LYQ
Sbjct: 1387 ----LRKTYRENVGGPGAPEGTPAG-RARGGSPAPLPAKVDEATSGLIRELAAVEDELYQ 1441
Query: 1563 EHV------PTSSASAGTPVEVGDRDF 1583
+ P +SA+ GT GD D+
Sbjct: 1442 RMLKGPPPEPAASAAQGT----GDPDW 1464
Score = 33.5 bits (75), Expect = 2.4
Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 13/65 (20%)
Query: 92 RPAAPAPAA------LVAQPGAPGAPADAGPEPVGTQEP-------GPDPIAAAVETAPA 138
+PA PA A L QP PA + P P+G Q+P P P AAA A
Sbjct: 604 QPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATT 663
Query: 139 PDGGP 143
P P
Sbjct: 664 PQPSP 668
Score = 33.5 bits (75), Expect = 2.4
Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 54 PPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPAD 113
PP L P PP P + ++ L +A P+ ++ Q A GAPA
Sbjct: 923 PPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPA- 981
Query: 114 AGPEPVGTQEPGPDPIAAAVETAPAPDGGP 143
P+ + P P A+ + + AP G P
Sbjct: 982 -APQTSTSLGPLTSPAASVLVSGQAPSGTP 1010
Score = 33.5 bits (75), Expect = 2.4
Identities = 93/396 (23%), Positives = 135/396 (34%), Gaps = 79/396 (19%)
Query: 564 ARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGST 623
+R +P+ H G GP P A PP LPT + G S
Sbjct: 1205 SRSLGLPIAASSEGHRLPGH-GPLSSSAPGASTQP-PPHLPTKLVIRHGGA---GGSPSV 1259
Query: 624 VYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPV 683
++ + SS S S A ++ + +GP+ ++ P + Y+ + GL +
Sbjct: 1260 TWARASSSLSSSSSSSSAASSLDADE--------DGPMPSRNRPPIKTYEARSRI-GLKL 1310
Query: 684 GSVPAPACPPSLQQHFPDPAMSFAPVLPPPST-----PMPTGPGQPAPPGQ-----QPPP 733
+ DP P PP+T P P P P P GQ PP
Sbjct: 1311 KIKQEAGLSKVVHNTALDPVHQPPP---PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPP 1367
Query: 734 LAQPTPLPQVLAPQ-PVVPLQ---------PVPPHLPPYLAPASQVGAPAQLKPLQMPQA 783
A P P AP P +PL+ P P P A ++ G+PA L P ++ +A
Sbjct: 1368 PAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTP--AGRARGGSPAPL-PAKVDEA 1424
Query: 784 P---LQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
++ LA V ++ + P A PD +PP + SP V
Sbjct: 1425 TSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQ 1484
Query: 841 PSLAAPLPPASPALP-LQA-----VKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGV 894
S ++ P LQ+ + L PG RT P+ P
Sbjct: 1485 ASFSSDSPQDDTLTEHLQSAIDSILNLQQAPG-------RTPAPSYP------------- 1524
Query: 895 AALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHH 930
H+A A P P P P PPS H+
Sbjct: 1525 -----HAASAGTPASPP-----PLHRPEAYPPSSHN 1550
Score = 31.6 bits (70), Expect = 9.1
Identities = 54/211 (25%), Positives = 73/211 (34%), Gaps = 42/211 (19%)
Query: 1318 VAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQ--AGPSN 1375
VAE P P P PP + + +AP + L + L ++ + GP
Sbjct: 1342 VAE-PPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGA 1400
Query: 1376 PPGAP--------PAPLAPSSPPVTA-LPQDGAAPATSTM--------PEPASGTASQAG 1418
P G P PAPL T+ L ++ AA PEPA+ A G
Sbjct: 1401 PEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTG 1460
Query: 1419 -----GPGTPQGLTSELETS------------QPLAETHEAPLAVQPLV-VGLAPC-TPA 1459
PG P + E+ Q T A+ ++ + AP TPA
Sbjct: 1461 DPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPA 1520
Query: 1460 PEAASTRDASAPREPLPPPAPE---PSPHSG 1487
P A P P P PE PS H+G
Sbjct: 1521 PSYPHAASAGTPASPPPLHRPEAYPPSSHNG 1551
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 121 bits (303), Expect = 9e-27
Identities = 109/417 (26%), Positives = 133/417 (31%), Gaps = 59/417 (14%)
Query: 693 PSLQQHFPDPAMSFAPVLPPPSTPMP--TGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVV 750
PS P P + LPP +TP P T P P PP+ T P P P +
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 751 PLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIP-VVPPITPLAG 809
PP P P+ P+ P P P PP P P PITP A
Sbjct: 1459 STTTTPP---PTTTPSPPTTTPSP--PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS 1513
Query: 810 IDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPL 869
LPP P T PPP +P+ P P+ P + L P PP
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTT-TPS---PPTTTPITPPTSTTTLPPTTTPSPPPTTT 1569
Query: 870 AMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPH 929
P T P+ P T P P P T PP+
Sbjct: 1570 TTPPPTTTPSPPTTTT---------------------PSPPTITTTTPPPTTTPSPPTTT 1608
Query: 930 HTVQNMRATPPQPALPP------QPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQ 983
T TP P P TLPP P PT P PP T P P
Sbjct: 1609 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP--PPTTTPSPPTTTTPS 1666
Query: 984 PMLPPQPVLPP--QPALPVRPEPLQPHLP-EQAAPAATPGSQILLGHPAPYAVDVAAQVP 1040
P + PP P+ P+ P P +P TP S P
Sbjct: 1667 PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS--------PITTTTTPSST 1718
Query: 1041 TVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP 1097
T P PP ++ P P P+ P +++ T+ + S P T L P PP
Sbjct: 1719 TTPSPPPTTMTTPSP-TTTPSPP------TTTMTTLPPTTTSSPLTTTPLPPSITPP 1768
Score = 118 bits (296), Expect = 6e-26
Identities = 110/445 (24%), Positives = 131/445 (29%), Gaps = 64/445 (14%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
PSP SPP + LP PT P P + P PP+ P P +
Sbjct: 1399 PSPPTTTPSPPPTSTTTLP-----------PTTTPSPPTTTTTTP--PPTTT---PSPPI 1442
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHL----P 760
+ PP +TP P PP P TP P P P PP P
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502
Query: 761 PYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPI-PVVPPITPLAGIDGLPPALPD 819
P P + + L P P P PP P P PITP LPP
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1562
Query: 820 LPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPN 879
P T PPP + P+ P PP P PP P T P+
Sbjct: 1563 SPPPTTTTTPPP---TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS 1619
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATP 939
P T P + PP ++ LP PT P P T T
Sbjct: 1620 PPTTTP---ITPP--------TSTTTLP-------------PTTTPSPPPTT-----TTT 1650
Query: 940 PQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999
P P P P P P T P P P P P M P P P +
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710
Query: 1000 VRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLL 1059
P P T P+P +PP S P
Sbjct: 1711 TTTTPSSTTTPSPPPTTMTT--------PSPTTTPSPPTTTMTTLPPTTTSS---PLTTT 1759
Query: 1060 PAAPELLPQFPSSLATVSASVQSVP 1084
P P + P S +T + + VP
Sbjct: 1760 PLPPSITPPTFSPFSTTTPTTPCVP 1784
Score = 114 bits (285), Expect = 1e-24
Identities = 109/408 (26%), Positives = 131/408 (32%), Gaps = 67/408 (16%)
Query: 716 PMPTGPGQPAPPGQQP-PPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQ 774
PM P+PP P PP T LP P P PP P P+ +
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPP---PTTTPSPPITTTTT 1447
Query: 775 LKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYF 834
P P P+ PP P P P TP PP P T PPP
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSP--PTTTPS------PPTTTPSPPTTTTTTPPPTT- 1498
Query: 835 SPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGV 894
+P+ P P+ P + L P PP P T P+ P T P + PP
Sbjct: 1499 TPS---PPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTP---ITPP-- 1550
Query: 895 AALSIHSAVAQLPGQPVYPAAFPQMAPTDVP-PSPHHTVQNMRATPPQPALPPQPTLPPQ 953
++ LP PT P P P T T P P P+ P
Sbjct: 1551 ------TSTTTLP-------------PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTI 1591
Query: 954 PVLPPQPTLPPQP----VLPPQPTRPPQ-----PVLPP--QPMLPPQPVLPPQPALPVRP 1002
P PT P P P PT P P+ PP LPP P P P
Sbjct: 1592 TTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1651
Query: 1003 EPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAA 1062
P P TP I P ++ + T P PP ++ P P P++
Sbjct: 1652 PPTTTPSP---PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSP-TTTPSS 1707
Query: 1063 PELLPQFPSSLATVS-----------ASVQSVPTQTATLLPPANPPLP 1099
P PSS T S + S PT T T LPP P
Sbjct: 1708 PITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSP 1755
Score = 91.3 bits (225), Expect = 1e-17
Identities = 85/326 (26%), Positives = 104/326 (31%), Gaps = 53/326 (16%)
Query: 796 PPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALP 855
P P P P LPP P T PPP +P+ + + P P +P+ P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTT-TPSPPITTTTTPPPTTTPSPP 1457
Query: 856 LQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQ--PVYP 913
+ P P P T P+ P T P +PP + P P+ P
Sbjct: 1458 ISTTTTPPPTTTPSPP---TTTPSPPTTTP----SPPTTTTTTPPPTTTPSPPTTTPITP 1510
Query: 914 AAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973
A P PSP T TPP P PT P + PP T P P P
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTT---TPPPTTTPSPPTTTP--ITPPTSTTTLPPTTTPSP- 1564
Query: 974 RPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAV 1033
PP P P P P P P P T + P P
Sbjct: 1565 -------PPTTTTTPPPTTTPSPPTTTTPSP----------PTITTTT------PPP--- 1598
Query: 1034 DVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATV--SASVQSVPTQTATLL 1091
T P PP + P P P+ P P P + T + S P T T
Sbjct: 1599 ------TTTPSPPTTTTTTP-PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1651
Query: 1092 PPANPPLPGGPGIASPCPTVQLTVEP 1117
PP P P P +P P + T P
Sbjct: 1652 PPTTTPSP--PTTTTPSPPITTTTTP 1675
Score = 76.6 bits (187), Expect = 2e-13
Identities = 120/532 (22%), Positives = 152/532 (28%), Gaps = 42/532 (7%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3857
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3858 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3914
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3915 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3974
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3975 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4023
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 4024 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4082
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 4083 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4140
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATP-GSQILLGHPAPYAVDVAAQVPTVPVPPAAVLS 1051
P P P P TP G+Q P + V P P
Sbjct: 4141 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTG 4196
Query: 1052 PPLPEVLLPAAPELLPQFP---SSLATVSASVQSVPTQTATLL---PPANPPLPGGPGIA 1105
PP P A EL P SS S S S T++ TLL PPA P
Sbjct: 4197 PPTHTSTAPIA-ELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255
Query: 1106 SPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAF 1157
PT + ++ PPG P + G S + + + A+
Sbjct: 4256 PTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAW 4307
Score = 72.0 bits (175), Expect = 6e-12
Identities = 63/243 (25%), Positives = 79/243 (32%), Gaps = 24/243 (9%)
Query: 907 PGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQP 966
P P + P + T +PP+ + T P P P P P P PT P P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSP--PITTTTTPPPTTTPSP 1456
Query: 967 VLPPQPTRPPQPVLPPQPMLPPQPVLPPQP--ALPVRPEPLQPHLPEQAAPAATPGSQIL 1024
+ T PP P P P P P P P P P P S
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516
Query: 1025 LGH---PAPYAVDVAAQVPTV-PVPPAAV-LSPPLPEVLLPAAPELLPQFPSSLATV--- 1076
L P+P PT P PP ++PP LP P P P + T
Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTTTTPPP 1574
Query: 1077 -------SASVQSVPTQTATLLPPANPPLPGGPGIASPCPTV---QLTVEPVQEEQASQD 1126
+ + S PT T T PP P P +P PT T P+ ++
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634
Query: 1127 KPP 1129
PP
Sbjct: 1635 LPP 1637
Score = 67.0 bits (162), Expect = 2e-10
Identities = 114/521 (21%), Positives = 146/521 (28%), Gaps = 52/521 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3788
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3789 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3845
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3905
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3906 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3954
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3955 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4013
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 4014 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4071
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 4072 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 4126
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 4127 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4186
Query: 1098 LPGGPGIASPCPTVQLTVEPVQEEQASQDKP-PGLPQSCES 1137
P G + PT + P+ E S P PQ+ S
Sbjct: 4187 TPTPTGTQTGPPT-HTSTAPIAELTTSNPPPESSTPQTSRS 4226
Score = 66.2 bits (160), Expect = 3e-10
Identities = 110/500 (22%), Positives = 136/500 (27%), Gaps = 51/500 (10%)
Query: 646 SPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMS 705
+P +P + V P P+ Q PT P +V P Q P +
Sbjct: 1892 NPTPPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1949
Query: 706 FAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAP 765
V P TP PTG P PTP P P+ P
Sbjct: 1950 TTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2006
Query: 766 ASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPTA 823
+Q + P P PI +TP G P P T
Sbjct: 2007 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2066
Query: 824 TVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPNA 880
TV P P P P +P V P P G P P T
Sbjct: 2067 TVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2115
Query: 881 PATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMRA 937
P P P ++ + V P P P T V P+P T Q
Sbjct: 2116 PTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2174
Query: 938 TPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP- 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2175 TPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2232
Query: 994 PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLSP 1052
P P P P TP G P + P P P +P
Sbjct: 2233 PTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQTP 2287
Query: 1053 PLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------PL 1098
+ + P Q P++ T + +V PT T T P P P
Sbjct: 2288 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2347
Query: 1099 PGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2348 PTPTGTQTPTTTPITTTTTV 2367
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 1913 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1971
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 1972 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2028
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2029 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2088
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2089 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2137
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2138 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2196
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2197 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2254
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2255 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2309
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2369
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2370 TPTPTGTQTPTTTPITTTTTV 2390
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 1936 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1994
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 1995 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2051
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2111
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2112 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2160
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2161 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2219
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2220 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2277
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2278 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2332
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2333 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2392
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2393 TPTPTGTQTPTTTPITTTTTV 2413
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 1959 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2017
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2018 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2074
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2075 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2134
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2135 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2183
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2184 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2242
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2243 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2300
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2355
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTV 2436
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 1982 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2040
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2041 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2097
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2157
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2158 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2206
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2207 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2265
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2266 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2323
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2378
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2379 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2438
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTV 2459
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2005 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2063
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2064 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2120
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2121 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2180
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2181 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2229
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2230 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2288
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2289 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2401
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTV 2482
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2028 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2087 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2143
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2144 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2203
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2204 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2252
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2253 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2311
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2312 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2369
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2370 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2424
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2425 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2484
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTV 2505
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2110 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2166
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2226
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2227 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2275
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2276 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2334
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2335 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2392
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2393 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2447
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2448 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTV 2528
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2132
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2133 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2189
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2190 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2249
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2250 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2298
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2299 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2357
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2358 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2470
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTV 2551
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2156 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2212
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2213 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2272
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2273 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2321
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2322 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2380
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2381 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2438
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2493
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2494 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2553
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTV 2574
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2120 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2179 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2235
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2236 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2295
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2296 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2344
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2345 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2403
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2404 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2516
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2517 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2576
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTV 2597
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2202 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2258
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2259 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2318
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2319 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2367
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2368 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2426
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2427 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2484
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2539
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2540 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2599
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTV 2620
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2225 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2281
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2282 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2341
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2342 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2390
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2391 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2449
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2450 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2562
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2563 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2622
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTV 2643
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2248 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2304
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2364
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2365 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2413
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2414 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2472
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2473 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2585
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTV 2666
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2271 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2327
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2328 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2387
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2388 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2436
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2437 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2495
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2496 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2553
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2608
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2609 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTV 2689
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2294 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2350
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2351 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2410
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2411 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2459
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2460 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2518
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2519 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2576
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2631
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2632 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTV 2712
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2258 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2317 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2373
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2374 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2433
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2434 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2482
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2483 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2541
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2542 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2599
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2654
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTV 2735
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2340 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2396
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2397 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2456
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2457 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2505
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2506 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2564
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2565 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2622
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2677
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2678 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTV 2758
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2363 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2419
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2479
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2480 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2528
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2529 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2587
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2588 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2700
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2760
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTV 2781
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2386 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2442
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2443 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2503 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2551
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2552 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2610
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2611 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2723
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2724 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2783
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTV 2804
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2409 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2465
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2466 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2525
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2526 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2574
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2575 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2633
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2634 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2746
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2747 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2806
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTV 2827
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2432 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2488
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2489 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2548
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2549 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2597
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2598 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2656
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2657 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2769
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTV 2850
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2455 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2511
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2571
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2572 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2620
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2621 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2679
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2680 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2792
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2793 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2852
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTV 2873
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2478 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2534
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2535 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2594
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2595 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2643
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2644 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2702
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2703 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2760
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2815
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2816 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTV 2896
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2501 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2557
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2558 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2617
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2618 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2666
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2667 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2725
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2726 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2783
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2838
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2898
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTV 2919
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2524 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2580
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2640
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2641 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2689
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2690 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2748
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2749 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2806
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2861
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2862 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2921
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTV 2942
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2546
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2547 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2603
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2663
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2664 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2712
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2713 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2771
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2772 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2884
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2885 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTV 2965
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2570 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2626
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2686
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2687 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2735
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2736 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2794
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2795 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2852
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2907
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2908 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2967
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTV 2988
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2593 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2649
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2650 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2709
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2710 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2758
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2759 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2817
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2818 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2930
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2931 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTV 3011
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2616 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2672
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2673 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2732
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2733 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2781
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2782 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2840
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2841 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2898
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2953
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2954 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTV 3034
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2639 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2695
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2755
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2756 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2804
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2805 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2863
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2864 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2921
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2976
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 2977 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3036
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTV 3057
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2662 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2718
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2778
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2779 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2827
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2828 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2886
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2887 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 2999
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3000 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTV 3080
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2684
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2685 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2741
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2742 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2801
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2802 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2850
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2851 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2909
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2910 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2967
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3022
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3023 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3082
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTV 3103
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2708 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2764
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2765 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2824
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2825 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2873
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2874 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2932
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2933 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3045
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3105
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTV 3126
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2731 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2787
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2847
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2848 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2896
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2897 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2955
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2956 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3068
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTV 3149
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2754 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2810
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2870
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2871 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2919
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2920 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2978
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 2979 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3036
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3091
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3092 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTV 3172
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2777 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2833
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2893
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2894 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2942
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2943 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3001
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3002 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3114
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3174
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTV 3195
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2800 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2856
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2857 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2916
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2917 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2966 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3024
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3025 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3082
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3137
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3197
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTV 3218
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2823 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2879
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2880 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2939
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2940 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2988
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 2989 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3047
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3048 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3105
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3160
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3161 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTV 3241
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2846 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2902
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2903 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2962
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2963 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3011
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3012 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3070
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3071 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3183
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTV 3264
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2869 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2925
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2926 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2985
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 2986 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3034
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3035 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3093
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3094 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3206
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3266
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTV 3287
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2892 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2948
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2949 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3008
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3009 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3057
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3058 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3116
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3117 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3174
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3229
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3289
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTV 3310
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2915 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2971
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3031
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3032 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3080
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3081 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3139
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3140 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3197
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3252
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3253 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTV 3333
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2938 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2994
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3055 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3103
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3104 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3163 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3275
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3335
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTV 3356
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2961 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3017
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3018 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3077
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3078 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3126
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3127 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3185
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3186 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3298
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTV 3379
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 2984 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3040
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3041 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3100
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3101 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3149
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3150 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3208
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3209 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3266
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3321
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTV 3402
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3007 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3063
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3064 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3123
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3124 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3172
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3173 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3231
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3232 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3289
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3344
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3404
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTV 3425
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3030 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3086
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3087 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3146
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3147 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3195
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3196 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3254
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3255 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3367
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3368 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTV 3448
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3053 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3109
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3110 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3169
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3170 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3218
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3219 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3277
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3278 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3335
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3390
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTV 3471
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3076 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3132
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3192
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3193 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3242 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3300
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3301 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3413
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3474 TPTPTGTQTPTTTPITTTTTV 3494
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3099 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3155
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3215
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3216 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3264
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3265 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3323
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3324 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3436
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3437 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTV 3517
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3122 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3178
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3238
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3239 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3287
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3288 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3346
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3347 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3404
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3459
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3519
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTV 3540
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3145 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3201
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3202 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3261
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3262 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3310
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3311 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3370 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3482
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3542
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTV 3563
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3168 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3224
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3225 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3284
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3285 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3333
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3334 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3392
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3393 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3505
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTV 3586
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3191 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3247
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3248 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3307
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3308 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3356
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3357 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3415
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3416 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3474 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3528
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3588
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTV 3609
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3214 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3270
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3330
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3331 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3379
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3380 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3438
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3439 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3551
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTV 3632
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3237 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3293
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3294 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3353
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3354 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3402
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3403 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3461
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3462 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3519
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3574
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTV 3655
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3260 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3316
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3317 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3376
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3377 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3425
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3426 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3484
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3485 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3542
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3597
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3657
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3658 TPTPTGTQTPTTTPITTTTTV 3678
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3283 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3339
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3340 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3399
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3400 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3448
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3449 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3507
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3508 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3620
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3680
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTV 3701
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3306 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3362
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3363 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3422
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3423 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3471
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3472 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3530
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3531 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3588
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3643
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTV 3724
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3329 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3385
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3386 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3445
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3446 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3494
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3495 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3553
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3554 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3666
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3726
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTV 3747
Score = 65.5 bits (158), Expect = 6e-10
Identities = 109/501 (21%), Positives = 138/501 (27%), Gaps = 50/501 (9%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 3352 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3408
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGL--PPALPDLPT 822
+Q + P P PI +TP G P P T
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3468
Query: 823 ATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK-LPHPPGA--PLAMPCRTIVPN 879
TV P P P P +P V P P G P P T
Sbjct: 3469 TTVTPTPTPT-----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3517
Query: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQP--VYPAAFPQMAPTDVPPSPHHT-VQNMR 936
P P P ++ + V P P P T V P+P T Q
Sbjct: 3518 TPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3576
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPP---QPVLPPQPTRPPQPVLPPQPMLPPQPVLP 993
TP PT P P PT P + P PT P+ V P
Sbjct: 3577 TTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634
Query: 994 -PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP-PAAVLS 1051
P P P P TP G P + P P P +
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPTPTGTQT 3689
Query: 1052 PPLPEV-----LLPAAPELLPQFPSSLA-TVSASVQSVPTQTATLLPPANP--------P 1097
P + + P Q P++ T + +V PT T T P P P
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3749
Query: 1098 LPGGPGIASPCPTVQLTVEPV 1118
P G +P T T V
Sbjct: 3750 TPTPTGTQTPTTTPITTTTTV 3770
Score = 60.5 bits (145), Expect = 2e-08
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 31/288 (10%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376
P + P SPP ++ PP + S P ++ + L P+
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP---------PTTT 1561
Query: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPL 1436
P PP ++PP T P +P T+T P P + T + TP T+ T P
Sbjct: 1562 PSPPPT--TTTTPPPTTTP----SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPT 1615
Query: 1437 AETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQP 1496
T +P P+ + T P + + P P P P P + TP P +
Sbjct: 1616 --TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP-PTTTTPSPPITTT 1672
Query: 1497 APLLPAAVGAVSLATSQLPSPPL------GPTVPPQPP-----SALESDGEGPPPRVGFV 1545
P + + T+ PSPP PT P P + + PPP
Sbjct: 1673 TTPPPTTTPSSPITTT--PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTT 1730
Query: 1546 DSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQP 1593
S + T+ TSS TP+ T P P
Sbjct: 1731 PSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTP 1778
Score = 59.3 bits (142), Expect = 4e-08
Identities = 54/220 (24%), Positives = 75/220 (34%), Gaps = 24/220 (10%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376
P + P SPP ++ PP + S P ++ P+ S + + P P
Sbjct: 1410 PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITT--TTTPPPTTTPSPPISTTTTP--P 1465
Query: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELET---- 1432
P P+P + P T P T+T P P + + P TP T+ L
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTT--TTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTP 1523
Query: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREP-----LPPPAPEPSPHSG 1487
S P T P P P TP + + P P PPP PSP
Sbjct: 1524 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP--- 1580
Query: 1488 TPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQP 1527
P P+P + + + PSPP T P P
Sbjct: 1581 ---PTTTTPSP---PTITTTTPPPTTTPSPPTTTTTTPPP 1614
Score = 52.0 bits (123), Expect = 6e-06
Identities = 56/222 (25%), Positives = 74/222 (33%), Gaps = 34/222 (15%)
Query: 1330 SPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP--LAPS 1387
SPP S PP S + P P+ S + P PP P+P +
Sbjct: 1400 SPPTTTPS-PPPTSTTTLP----------PTTTPSPPTTTTTTP--PPTTTPSPPITTTT 1446
Query: 1388 SPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQ 1447
+PP T P +T+T P P + + P P S P T P
Sbjct: 1447 TPPPTTTPSPPI--STTTTPPPTTTPSPPTTTPSPP-----TTTPSPPTTTTTTPPPTTT 1499
Query: 1448 PLVVGLAPCTPAPEAASTRDASAPREP-----LPPPAPEPSPHSGTPQPALGQPAPLLPA 1502
P P TP + + P P PPP PSP + TP L P
Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559
Query: 1503 AVGAVSLATSQLPSPPLGPTVP----PQPPSALESDGEGPPP 1540
+ T+ P P P+ P P PP+ + PPP
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTT---PPP 1598
Score = 45.1 bits (105), Expect = 8e-04
Identities = 80/357 (22%), Positives = 108/357 (30%), Gaps = 44/357 (12%)
Query: 645 PSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM 704
P+ Q + P++ + + P+ Q PT P +V P Q P
Sbjct: 4075 PTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4133
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
+ V P TP PTG P PTP P P+ P
Sbjct: 4134 TTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4190
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPIT------PLAG----IDGLP 814
+Q G P P+A++ PP P T PL + LP
Sbjct: 4191 TGTQTGPPT--------HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 4242
Query: 815 PALPDLPTATVPPVPP--PQYFSPAVIL--PSLAAPLPPASPALPLQAVKLPHPPGAPLA 870
PA+ T+T PP P P S L P PP +P P P
Sbjct: 4243 PAIE--MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP--TPST 4298
Query: 871 MPCRTIVPNAPATIPL----------LAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMA 920
+ T P PL L P V + + PG+ VY +
Sbjct: 4299 VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTC 4358
Query: 921 PTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQ 977
V S T++ + P P PT P P P P T+PP+
Sbjct: 4359 -YFVNCSLSCTLEFYNWSCPS---TPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPE 4411
Score = 40.8 bits (94), Expect = 0.015
Identities = 60/254 (23%), Positives = 81/254 (31%), Gaps = 67/254 (26%)
Query: 1318 VAEHPAPEAPESSPP----------LPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQL 1367
V P P ++ PP L S+ PPE+S E + L++
Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPP 4243
Query: 1368 LSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMP--EPASGT---ASQAGGPGT 1422
+ + PP P AP S + P P+T+T P P GT +S A P T
Sbjct: 4244 AIEMTSTAPPSTPTAPTTTSGGHTLSPP-----PSTTTSPPGTPTRGTTTGSSSAPTPST 4298
Query: 1423 PQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPE- 1481
Q T+ T P PL+ P ++ P P +S + P E
Sbjct: 4299 VQTTTTSAWTPTP------TPLST-PSIIRTTGLRPYP--SSVLICCVLNDTYYAPGEEV 4349
Query: 1482 ---------------------------PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQL 1514
PS S TP P+ P P P S
Sbjct: 4350 YNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKP----------SST 4399
Query: 1515 PSPPLGPTVPPQPP 1528
PS P T PP+ P
Sbjct: 4400 PSKPTPGTKPPECP 4413
Score = 40.0 bits (92), Expect = 0.025
Identities = 48/206 (23%), Positives = 66/206 (32%), Gaps = 31/206 (15%)
Query: 1373 PSNPPGAPPAPLAPSSPPV-TALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELE 1431
P+ P + P+ P T P T+T+ + T +Q P T T+
Sbjct: 4104 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTV 4161
Query: 1432 TSQPLAETHEAPLAVQPLVVGLAPCTPAPEAAST----RDASAPREPLPPPAPEPSPHSG 1487
T P + P TP P T ++AP L P P S
Sbjct: 4162 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELT--TSNPPPESS 4219
Query: 1488 TPQPALGQPAPL---------LPAAVGAVSLATSQLPS-------------PPLGPTVPP 1525
TPQ + +PL LP A+ S A P+ PP T PP
Sbjct: 4220 TPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP 4279
Query: 1526 QPPSALESDGEGPPPRVGFVDSTIKS 1551
P+ + G P V +T S
Sbjct: 4280 GTPTRGTTTGSSSAPTPSTVQTTTTS 4305
Score = 39.7 bits (91), Expect = 0.033
Identities = 39/153 (25%), Positives = 50/153 (32%), Gaps = 21/153 (13%)
Query: 1401 PATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAP 1460
P + P+ T + + P + L S P T P P TP P
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450
Query: 1461 EAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPP-- 1518
+ S P P PSP + TP P P+P P T+ PSPP
Sbjct: 1451 TTTPSPPISTTTTPPPTTT--PSPPTTTPSPPTTTPSP--PTTTTTTPPPTT-TPSPPTT 1505
Query: 1519 -----------LGPTVPPQPPSALESDGEGPPP 1540
L PT P PP+ + PPP
Sbjct: 1506 TPITPPASTTTLPPTTTPSPPTTTTTT---PPP 1535
Score = 34.3 bits (77), Expect = 1.4
Identities = 23/72 (31%), Positives = 27/72 (37%), Gaps = 3/72 (4%)
Query: 1041 TVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVS--ASVQSVPTQTATLLPPANPPL 1098
T P PP SPP P P P P++ T + S P T T PP P
Sbjct: 1397 TTPSPPTTTPSPP-PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 1099 PGGPGIASPCPT 1110
P +P PT
Sbjct: 1456 PPISTTTTPPPT 1467
>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
Length = 841
Score = 120 bits (300), Expect = 2e-26
Identities = 82/272 (30%), Positives = 139/272 (51%), Gaps = 20/272 (7%)
Query: 201 LGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDF 260
+G+GS+ V + +L R + ER+ ++EA++L L+HPNIV + +
Sbjct: 12 VGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKES 71
Query: 261 WESSAKGKRCIVLVTELMTSGTLKTYLKRFK--VMKPKVLRSWCRQILKGLLFLHTRTPP 318
WE G + +V G L LK K ++ + W QI L +LH +
Sbjct: 72 WEG---GDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEK--H 126
Query: 319 IIHRDLKCDNIFITGPTGSVKIGDLGLATL--KRASFAKSVIGTPEFMAPEMY-EEHYDE 375
I+HRDLK N+F+T T +K+GDLG+A + A ++IGTP +M+PE++ + Y+
Sbjct: 127 ILHRDLKTQNVFLT-RTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNY 185
Query: 376 SVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECIC 435
DV+A G C+ EMAT ++ ++ + +YR + + P + + PE+ E+I +
Sbjct: 186 KSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPP--MPRDYSPELAELIRTMLS 243
Query: 436 KNKEERYEIKDLLSH-------AFFAEDTGVR 460
K EER ++ +L +FF E T ++
Sbjct: 244 KRPEERPSVRSILRQPYIKRQISFFLEATKIK 275
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 119 bits (299), Expect = 3e-26
Identities = 146/527 (27%), Positives = 194/527 (36%), Gaps = 86/527 (16%)
Query: 724 PAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAP---AQLKPLQM 780
PAP QQPPP Q P P Q P P PP +P APA + P A P+
Sbjct: 750 PAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLE 809
Query: 781 PQAP---LQPLAQV--PPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVP------PVP 829
PQ P P+ P P P +PP P PP L + P P
Sbjct: 810 PQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQ 869
Query: 830 PPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPN-APATIPLLA 888
P + + A LP A P SPAL Q LP P P+A P + ++ + P PL +
Sbjct: 870 PSRPSNRAAALPPKPARPPAVSPAL-TQTPLLPQP---PMAQPPQVLLEDEEPPAPPLTS 925
Query: 889 VAPPGVAALSIHSAVAQLPGQPVYPAAFPQ-MAPTDVPPSPHHTVQNMRATPPQPALPPQ 947
+ L + P P+ P+ Q P +PP PH +VQ P P PPQ
Sbjct: 926 MQ----MQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQ 981
Query: 948 PTLPPQPVLPPQPTLPPQPV-LPP-------QPTRPPQPVLPPQPMLPPQPVLPPQPALP 999
P PPQ P PP+PV L P Q PPQ PP P P Q PPQPA P
Sbjct: 982 PQPPPQQQHQP----PPRPVHLQPMQFSTHIQQPPPPQGQQPPHPP-PGQQPPPPQPAKP 1036
Query: 1000 VR------------------------PEPLQPHLPEQA-----APAATPGSQILLGHPAP 1030
+ P PL H P+ + + P +
Sbjct: 1037 QQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQEL 1096
Query: 1031 YAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATL 1090
A V P V V + SP + P +P L P+ P ++ A V +P +
Sbjct: 1097 RAASVVQPQPLVVVKEEKIHSPIIRSE--PFSPSLRPEPPKHPESIKAPVH-LPQR---- 1149
Query: 1091 LPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQ---------SCESYGGS 1141
P P G P I P P +++Q + K P P+ S S
Sbjct: 1150 -PEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQK 1208
Query: 1142 DVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPR 1188
T+ + S +F R RAAR+ R +++ E A + +
Sbjct: 1209 HPTTPSSTAKSSSDSFEQFR---RAAREKEEREKALKAQAEHAEKEK 1252
Score = 103 bits (256), Expect = 2e-21
Identities = 125/478 (26%), Positives = 175/478 (36%), Gaps = 57/478 (11%)
Query: 553 KEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLAS 612
++ Q +P + PP P Q Q Q PP P P Q P + +A+
Sbjct: 744 QQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIAT 803
Query: 613 DSTFDSGQ--GSTVYSDSQSSQQSVML--GSLADAAPSPAQCVCSPPVSEGPVLPQSLPS 668
Q GS +Q + L L P P + P +++ V+
Sbjct: 804 QVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALH 863
Query: 669 LGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP-----TGPGQ 723
QQP+ P PA PP++ PA++ P+LP P P
Sbjct: 864 NALPQQPSRPSNRAAALPPKPARPPAV-----SPALTQTPLLPQPPMAQPPQVLLEDEEP 918
Query: 724 PAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQA 783
PAPP L +V P P++P V PP L P QL+ Q P
Sbjct: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQ--QQPPP 976
Query: 784 PLQPLAQVPPQM----PPIPV-VPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAV 838
P P Q PPQ PP PV + P+ I PP P PP PPP
Sbjct: 977 PPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPP-----PQGQQPPHPPP------- 1024
Query: 839 ILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRT-IVPNAPATIPLLAVAPPGVAAL 897
PP PA P Q ++ H P + P T + AP+ + + + +L
Sbjct: 1025 -----GQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSL 1079
Query: 898 SIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQN-------MRATPPQPALPPQPTL 950
+ S P Q V P A + V P P V+ +R+ P P+L P+P
Sbjct: 1080 THQSP----PQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPK 1135
Query: 951 PPQPV-----LPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPE 1003
P+ + LP +P + P V P RPP+ PP P P + +P PV P+
Sbjct: 1136 HPESIKAPVHLPQRPEMKPVDVGRP-VIRPPEQNAPP-PGAPDKDKQKQEPKTPVAPK 1191
Score = 73.2 bits (178), Expect = 3e-12
Identities = 70/242 (28%), Positives = 89/242 (36%), Gaps = 41/242 (16%)
Query: 929 HHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPP 988
HH Q +A P P PP P P QP PP P QP PP P PQ P PP
Sbjct: 741 HHHQQMQQAPAPVPQQPPPP--PQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP 798
Query: 989 Q------PVLPP--------------QPALPVRPEPLQPHLPE-----------QAAPAA 1017
PVL P QP L + L PHLP+ Q A +
Sbjct: 799 PFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVS 858
Query: 1018 TPGSQILLGHPAPYAVDVAAQVPTVP-----VPPAAVLSPPLPEVLLPAAPELL--PQFP 1070
P L + AA +P P V PA +P LP+ + P++L + P
Sbjct: 859 PPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP 918
Query: 1071 SSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPG 1130
+ S +Q Q + PP P LP + P P + P ++Q Q PP
Sbjct: 919 PAPPLTSMQMQLYLQQLQKVQPP-TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPP 977
Query: 1131 LP 1132
P
Sbjct: 978 PP 979
Score = 61.6 bits (148), Expect = 8e-09
Identities = 64/240 (26%), Positives = 89/240 (37%), Gaps = 51/240 (21%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK--EQPSFLASQQLLSQAGPS 1374
P+ P PE P P P S PP +Q + L + +QPS +++ P+
Sbjct: 826 PILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA 885
Query: 1375 NPPGAPPA----PLAPSSPPVTALPQ------DGAAPATSTMPEPASGTASQAGGPGTPQ 1424
PP PA PL P PP+ PQ + AP ++M Q P TP
Sbjct: 886 RPPAVSPALTQTPLLPQ-PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPL 944
Query: 1425 GLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSP 1484
+ ++++ P P P P + + P PPP P+P P
Sbjct: 945 LPSVKVQSQPP------------------PPLPPPPHPSVQQQLQQQPPPPPPPQPQPPP 986
Query: 1485 ---HSGTPQPALGQPAPLLPAAVGAVSLATS-QLPSPPLGPTVPPQPPSALESDGEGPPP 1540
H P+P QP + +T Q P PP G PP PP G+ PPP
Sbjct: 987 QQQHQPPPRPVHLQP----------MQFSTHIQQPPPPQGQ-QPPHPP-----PGQQPPP 1030
Score = 57.0 bits (136), Expect = 2e-07
Identities = 134/583 (22%), Positives = 190/583 (32%), Gaps = 120/583 (20%)
Query: 1373 PSNPPGAPPAPLAPSS-------PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQG 1425
P PP PP P P PP ++PQ AAPA + P P T P P
Sbjct: 757 PPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQ-AAPAMKSSPPPFIATQVPVLEPQLPGS 815
Query: 1426 LTSEL-ETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPE--- 1481
+ + +QP+ + L P P P ST + PPA
Sbjct: 816 VFDPIGHFTQPILHLPQPE---------LPPHLPQPPEHSTPPHLNQHAVVSPPALHNAL 866
Query: 1482 -PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPP 1540
P + + A P P P AV T LP PP+ QPP L D E P P
Sbjct: 867 PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMA-----QPPQVLLEDEEPPAP 921
Query: 1541 RVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGG 1600
+ S+ +L Q+ P + V+ QP
Sbjct: 922 -------PLTSMQMQLYLQQLQKVQPPTPLLPSVKVQ-------------SQPPP----- 956
Query: 1601 DLALPPVPKEAVSGRVQ---------LPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPR 1651
LPP P +V ++Q PQP ++ P R ++ S+ + P
Sbjct: 957 --PLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPP- 1013
Query: 1652 SMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARV-----EPTDRDGGEAGESSAEPPPS 1706
Q H P P +P +V P PS
Sbjct: 1014 ---------PQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPS 1064
Query: 1707 DMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQ-----DEWTLAS 1761
+ Q S Q+L + P QQ+V + + SVV Q E + S
Sbjct: 1065 PLMIHSPQMSQFQSL-------THQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHS 1117
Query: 1762 PHSLRYSAPPDVYLDEAPSSPD-VKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPV 1820
P P + E P P+ +K V Q V VG PV RPP
Sbjct: 1118 PIIRSEPFSPSL-RPEPPKHPESIKAPVHLPQRPEMKPVDVGRPV----------IRPPE 1166
Query: 1821 QKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFH----SQ 1876
Q + P G+ D K Q P + P+ ++ S+ H S
Sbjct: 1167 Q---NAPPPGAPDKDKQK------QEPKT--PVAPKKDLKIKNMGSWASLVQKHPTTPSS 1215
Query: 1877 SSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEI 1919
++ SSD+ + A +KE REK LK +E ++K+ +
Sbjct: 1216 TAKSSSDSFEQFRRAAREKE---EREKALKAQAEHAEKEKERL 1255
Score = 51.6 bits (122), Expect = 8e-06
Identities = 46/159 (28%), Positives = 63/159 (39%), Gaps = 36/159 (22%)
Query: 890 APPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPT 949
A PGV+ + ++ A P Q PQ P V +PH P PA+ P
Sbjct: 189 AKPGVSTVP-NTTQASTPPQ----TQTPQPNPPPVQATPH----------PFPAVTPDLI 233
Query: 950 L--PPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQP 1007
+ P V+PPQP P PV PPQP PP P PQPV P + P+P++
Sbjct: 234 VQTPVMTVVPPQPLQTPPPV-PPQPQPPPAPA--------PQPVQSHPPIIAATPQPVK- 283
Query: 1008 HLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPP 1046
G + P +D + P++P P
Sbjct: 284 ---------TKKGVKRKADTTTPTTIDPIHEPPSLPPEP 313
Score = 49.7 bits (117), Expect = 3e-05
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 11/126 (8%)
Query: 913 PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQP 972
P FP + P + +P TV + P +PPQP PP P P + PP PQP
Sbjct: 222 PHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQP 281
Query: 973 TRPPQPVLPPQPMLPP--------QPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQIL 1024
+ + V P P LPP+P + + P + P SQ
Sbjct: 282 VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQ-- 339
Query: 1025 LGHPAP 1030
HPAP
Sbjct: 340 -QHPAP 344
Score = 49.3 bits (116), Expect = 4e-05
Identities = 49/150 (32%), Positives = 58/150 (38%), Gaps = 27/150 (18%)
Query: 702 PAMSFAPVLPPPSTPMPTGPGQPAPPGQQ---------PPPLAQPTPLPQVLAPQPVVPL 752
P +S P STP T QP PP Q P L TP+ V+ PQP+
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250
Query: 753 QPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDG 812
PVPP P APA Q P Q P + P QP+ P T ID
Sbjct: 251 PPVPPQPQPPPAPAPQ---PVQSHPPIIAATP-QPVKTKKGVKRKADTTTPTT----IDP 302
Query: 813 L--PPALPDLPTAT--------VPPVPPPQ 832
+ PP+LP P T PV PP+
Sbjct: 303 IHEPPSLPPEPKTTKLGQRRESSRPVKPPK 332
Score = 47.4 bits (111), Expect = 2e-04
Identities = 45/165 (27%), Positives = 59/165 (35%), Gaps = 15/165 (9%)
Query: 1399 AAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTP 1458
A P ST+P +QA P PQ T + A H P L+V T
Sbjct: 189 AKPGVSTVPN-----TTQASTP--PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTV 241
Query: 1459 APEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL-LPAAVGAVSLATSQLPSP 1517
P P +P PPPAP P P P P P+ V + T+
Sbjct: 242 VPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTID 301
Query: 1518 PL--GPTVPPQPPSA-----LESDGEGPPPRVGFVDSTIKSLDEK 1555
P+ P++PP+P + ES PP+ DS EK
Sbjct: 302 PIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEK 346
Score = 44.3 bits (103), Expect = 0.001
Identities = 32/100 (32%), Positives = 37/100 (37%), Gaps = 7/100 (7%)
Query: 722 GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMP 781
G P P Q + PQ PQP P PH P + P V P M
Sbjct: 187 GTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPV------MT 240
Query: 782 QAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLP 821
P QPL Q PP +PP P PP + PP + P
Sbjct: 241 VVPPQPL-QTPPPVPPQPQPPPAPAPQPVQSHPPIIAATP 279
Score = 42.7 bits (99), Expect = 0.004
Identities = 35/138 (25%), Positives = 48/138 (34%), Gaps = 20/138 (14%)
Query: 667 PSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPST----PMPTGPG 722
P + T A P P P PP P PA++ ++ P P P
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250
Query: 723 QPAPPGQQPPPLAQPTPLPQ-VLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMP 781
P PP QPP P P PQ V + P++ P P + + P + P+
Sbjct: 251 PPVPPQPQPP----PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI--- 303
Query: 782 QAPLQPLAQVPPQMPPIP 799
PP +PP P
Sbjct: 304 --------HEPPSLPPEP 313
Score = 40.8 bits (94), Expect = 0.015
Identities = 36/156 (23%), Positives = 51/156 (32%), Gaps = 10/156 (6%)
Query: 796 PPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALP 855
P + VP T + P+ P P P P ++ + +PP P
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250
Query: 856 LQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAA 915
P PP AP P V + P P++A P V V +
Sbjct: 251 PPVPPQPQPPPAPAPQP----VQSHP---PIIAATPQPV---KTKKGVKRKADTTTPTTI 300
Query: 916 FPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP 951
P P +PP P T R +P PP+ +P
Sbjct: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
Score = 37.0 bits (84), Expect = 0.22
Identities = 64/264 (24%), Positives = 86/264 (32%), Gaps = 34/264 (12%)
Query: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPP 1381
P P P+ PP PP P + ++ P Q P PPG P
Sbjct: 975 PPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQP------PHPPPGQQP 1028
Query: 1382 APLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGP--------GTPQGLTSE---L 1430
P P+ P + Q +P ++G +A P Q LT +
Sbjct: 1029 PPPQPAKP--QQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQ 1086
Query: 1431 ETSQPLAETHEAPLAV--QPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGT 1488
+ QP + A V QPLVV + S S P P P P P S
Sbjct: 1087 QNVQPKKQELRAASVVQPQPLVV-----VKEEKIHSPIIRSEPFSPSLRPEPPKHPESIK 1141
Query: 1489 PQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDST 1548
L Q + P VG + PP PP P + E P D
Sbjct: 1142 APVHLPQRPEMKPVDVGRPVI------RPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLK 1195
Query: 1549 IKSLDEKLRTLLYQEHVPTSSASA 1572
IK++ L Q+H T S++A
Sbjct: 1196 IKNMGS--WASLVQKHPTTPSSTA 1217
Score = 35.8 bits (81), Expect = 0.48
Identities = 49/217 (22%), Positives = 80/217 (36%), Gaps = 44/217 (20%)
Query: 1236 DFILQAE--RETFIEQMKDV-MDKAEDMLSEDTDADRG-SDPGTSPPHLSTCG----LGT 1287
D +L AE + F++++ ++ ++ E M+ + RG + GT+ P +ST T
Sbjct: 145 DIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQAST 204
Query: 1288 GEESRQSQANAP----------------VYQQNVLHTGKRWFIICPVAEHPAPEAPESSP 1331
+++ Q N P + Q V+ + P P P+ P +
Sbjct: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
Query: 1332 PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP-SNPPGAPPAPLA----- 1385
P P+ S PP + P K + K + A + P PP PP P
Sbjct: 265 PQPVQSHPPIIAATPQPVKTKKGVKRK----ADTTTPTTIDPIHEPPSLPPEPKTTKLGQ 320
Query: 1386 ------PSSPPVTALPQDGAAPATSTMPEPASGTASQ 1416
P PP +P PA PE +S + Q
Sbjct: 321 RRESSRPVKPPKKDVPDSQQHPA----PEKSSKVSEQ 353
Score = 34.3 bits (77), Expect = 1.4
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 11/92 (11%)
Query: 1038 QVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPAN-- 1095
Q P PP P P V P+L+ Q P V V P QT +PP
Sbjct: 209 QTPQPNPPPVQATPHPFPAV----TPDLIVQTP-----VMTVVPPQPLQTPPPVPPQPQP 259
Query: 1096 PPLPGGPGIASPCPTVQLTVEPVQEEQASQDK 1127
PP P + S P + T +PV+ ++ + K
Sbjct: 260 PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
Score = 33.1 bits (74), Expect = 3.1
Identities = 54/212 (25%), Positives = 79/212 (37%), Gaps = 21/212 (9%)
Query: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEP-EADQHLLPPTLPTS 606
P +P Q + + PP P Q + QP PP+P +P + QH P S
Sbjct: 992 PPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKS 1051
Query: 607 ATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSE--GPVLPQ 664
++ ++ ++S S QS+ SP Q P E + Q
Sbjct: 1052 -DPYSTGHLREAPSPLMIHSPQMSQFQSL-------THQSPPQQNVQPKKQELRAASVVQ 1103
Query: 665 SLPSLGAYQQPTAAPGLPVGSVP-APACPPSLQQHFPDPAMSFAPV-LPPPSTPMPTGPG 722
P + ++ +P + S P +P+ P +H P APV LP P G
Sbjct: 1104 PQPLVVVKEEKIHSP--IIRSEPFSPSLRPEPPKH---PESIKAPVHLPQRPEMKPVDVG 1158
Query: 723 QPA--PPGQQPPPLAQPTPLPQVLAPQ-PVVP 751
+P PP Q PP P Q P+ PV P
Sbjct: 1159 RPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAP 1190
Score = 32.7 bits (73), Expect = 4.1
Identities = 27/103 (26%), Positives = 34/103 (33%), Gaps = 15/103 (14%)
Query: 1440 HEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQP--- 1496
H + P V P P + ++P PPP P P P P
Sbjct: 742 HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801
Query: 1497 -------APLLPAAV----GAVSLATSQLPSPPLGPTVPPQPP 1528
P LP +V G + LP P L P + PQPP
Sbjct: 802 ATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHL-PQPP 843
Score = 32.0 bits (71), Expect = 6.9
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 25/91 (27%)
Query: 1466 RDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPP 1525
+ A AP PPP P+ P PQ Q P PP P++P
Sbjct: 747 QQAPAPVPQQPPPPPQQPPPPPPPQ-------------------QQQQPPPPPPPPSMPQ 787
Query: 1526 QPPSALESDGEGPPPRVGFVDSTIKSLDEKL 1556
Q A++S PPP F+ + + L+ +L
Sbjct: 788 QAAPAMKS---SPPP---FIATQVPVLEPQL 812
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 115 bits (289), Expect = 4e-25
Identities = 129/459 (28%), Positives = 178/459 (38%), Gaps = 100/459 (21%)
Query: 709 VLPPPSTPMPTGPGQPAPPGQQPP----------------PLAQPTPLPQVLAPQPVVPL 752
++PP P P + PP + P P PT +P+VL P+ VVP
Sbjct: 10449 IIPPKKPPTKVVP-RKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPE 10507
Query: 753 QPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDG 812
+ VP + PA + AP P ++P+AP + VP + P+P
Sbjct: 10508 KKVP------VPPAKKPEAP----PPKVPEAPKE---VVPEKKVPVP------------- 10541
Query: 813 LPPALPDLPTATVPPVPP---PQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPL 869
PP P++P VP VP P+ P I P +P PP P P + V P AP
Sbjct: 10542 -PPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP-PPEVPEAPKEVVPEKKVPAAP- 10598
Query: 870 AMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPH 929
P P P+ P V PV P P++ PT VP P
Sbjct: 10599 --------PKKPEVTPVKVPEAP--------KEVVPEKKVPVPPPKKPEVPPTKVPEVPK 10642
Query: 930 HTVQNMR---ATPPQPALPPQPTL-PPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPM 985
V + A PP+P PP P+ V +P P + V P+P PPQ +PP+
Sbjct: 10643 VAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEP--PAEVVEEPEPAAPPQVTVPPKKP 10700
Query: 986 LPPQ---PVLPPQPALPVRPEPLQPH--LPEQAAPAATPGSQILLGHPAPYAVDVAAQVP 1040
+P + V+ +P LP P P +PE+ P P AP A+VP
Sbjct: 10701 VPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKP-----EAP-----PAKVP 10750
Query: 1041 TVP---VPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP 1097
VP VP V P PEV P +P+ P V +VP PP P
Sbjct: 10751 EVPKEVVPEKKVAVPKKPEV----PPAKVPEVPKK--PVLEEKPAVPVPERAESPP--PE 10802
Query: 1098 LPGGPGIASPCPTVQLTVE---PVQEEQASQDKPPGLPQ 1133
+ P +P + E PV EE+ + PP +P+
Sbjct: 10803 VYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPE 10841
Score = 113 bits (283), Expect = 2e-24
Identities = 161/685 (23%), Positives = 255/685 (37%), Gaps = 141/685 (20%)
Query: 504 KETPDEV----AQEMIESGFFHESD--VKIVAKSIRDRVALIQWRRERIWPALQPKEQQD 557
+E P+E +E E G FHE + +K+ + + + R E++ ++ E ++
Sbjct: 10375 EEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEE-----EHRVEKVHRVIEVFEAEE 10429
Query: 558 VGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFD 617
V +K + PP + PE + ++PP P + +
Sbjct: 10430 VEVFEKPKAPP---------------------KGPEISEKIIPPKKPPTKVVPRKEP--- 10465
Query: 618 SGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA 677
P+ V V E V P + + P
Sbjct: 10466 ---------------------------PAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV 10498
Query: 678 APGLPVGSVPAPACPPSLQQHFPDPAMSFAP--VLPPPSTPMPTGPGQPAPPGQQPPPLA 735
P V PP+ + P P + AP V+P P+P P +P P
Sbjct: 10499 LPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPP-PKKPEVP-------- 10549
Query: 736 QPTPLPQVLAPQPVVPLQPVPPHLP--PYLAPASQVGAPAQLKP-LQMPQAPLQPLAQVP 792
PT +P+V P+ VP + VP +P P P AP ++ P ++P AP + P
Sbjct: 10550 -PTKVPEV--PKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 793 PQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPP---PQYFSPAVILPSLAAPLP- 848
++P P + P + PP P++P VP VP P+ P I P +P P
Sbjct: 10607 VKVPEAP--KEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPE 10664
Query: 849 ----PASPAL---PLQAVKLPHPPGAP-LAMPCRTIVP--NAPATIPLLAVAPPGVAALS 898
P AL P + V+ P P P + +P + VP APA + PP V
Sbjct: 10665 VFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPP-VKVPE 10723
Query: 899 IHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMR-ATPPQPALPPQ--PTLPPQPV 955
+ V P+ P+ P VP P V + A P +P +PP P +P +PV
Sbjct: 10724 VPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPV 10783
Query: 956 LPPQPTLP-PQPV--LPPQPTRPPQPVLPPQPMLP----PQPVLP------PQPALPVRP 1002
L +P +P P+ PP+ P+ + P + + P P PV P PA+P P
Sbjct: 10784 LEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEP 10843
Query: 1003 EPLQPH--LPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEV--- 1057
+ + P +P P A P + P P V ++ P PP +PP +V
Sbjct: 10844 KKIIPEKKVPVIKKPEAPPPKE-----PEPEKVIEKPKLKPRPPPPPP--APPKEDVKEK 10896
Query: 1058 --LLPAAPEL----LPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTV 1111
L A P+ PQ P + V + LLP P P
Sbjct: 10897 IFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPE-----------PKE 10945
Query: 1112 QLTVEPVQEEQASQDKPPGLPQSCE 1136
++ ++ V ++ +++P P+ E
Sbjct: 10946 EVVLKSVLRKRPEEEEPKVEPKKLE 10970
Score = 96.7 bits (239), Expect = 2e-19
Identities = 147/594 (24%), Positives = 226/594 (38%), Gaps = 118/594 (19%)
Query: 581 AGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSL 640
A +P P P+ PEA + ++P
Sbjct: 10515 AKKPEAPPPKVPEAPKEVVP---------------------------------------- 10534
Query: 641 ADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFP 700
P P P ++ P +P++ ++ + P A P P P P P + ++ P
Sbjct: 10535 EKKVPVPPPKKPEVPPTKVPEVPKA--AVPEKKVPEAIP--PKPESPPPEVPEAPKEVVP 10590
Query: 701 DPAMSFAPVLPPPSTP--MPTGPGQ-------PAPPGQQPPPLAQPTPLPQVLAPQPVVP 751
+ + AP P TP +P P + P PP ++P PT +P+V P+ VP
Sbjct: 10591 EKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE--VPPTKVPEV--PKVAVP 10646
Query: 752 LQPVPPHLPPY-LAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGI 810
+ VP +PP +P +V + L+ P P + + + P PP VPP P+
Sbjct: 10647 EKKVPEAIPPKPESPPPEVFEEPEEVALEEP--PAEVVEEPEPAAPPQVTVPPKKPVP-- 10702
Query: 811 DGLPPAL----PDLPTATVPPVPP---PQYFSPAVILPSLAAPLPPASPALPLQAV--KL 861
+ PA+ P+LP VP VP P+ P V+ AP P P +P + V K
Sbjct: 10703 EKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAP-PAKVPEVPKEVVPEKK 10761
Query: 862 PHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAP 921
P P P + VP P P+L P S ++ +P A ++AP
Sbjct: 10762 VAVPKKPEVPPAK--VPEVPKK-PVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAP 10818
Query: 922 TDVPPSPHHTVQNMRATPPQPALPPQP-TLPPQPVLP--PQPTLPPQPVLPPQPTRPPQP 978
+ P P + P PA+P +P + P+ +P +P PP P P +P
Sbjct: 10819 EEEKPVP--VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPP-PKEPEPEKVIEKP 10875
Query: 979 VLPPQPMLPPQPVLPPQ----------PALPVRPEPLQPHLPE--QAAPAATPGSQ---- 1022
L P+P PP P PP+ A+P + P +P +PE + P PG +
Sbjct: 10876 KLKPRP--PPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVR 10933
Query: 1023 ILLGHPAPYAVDVAAQVPTVPVPP----AAVLSPPLPEVLLPAAPELLPQFP---SSLAT 1075
LL P + + P V L +V PA PE P P + T
Sbjct: 10934 KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT 10993
Query: 1076 VSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPP 1129
V+ + +P T +P P +P + +P P +P E + KPP
Sbjct: 10994 VTKRERKIPEPTK--VPEIKPAIP----LPAPEP------KPKPEAEVKTIKPP 11035
Score = 79.3 bits (194), Expect = 4e-14
Identities = 126/569 (22%), Positives = 200/569 (35%), Gaps = 122/569 (21%)
Query: 552 PKEQQDVGSPDKARGPP--VP-LQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSAT 608
P+++ V P K PP VP + + + PP+PE P PP +P +
Sbjct: 10534 PEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP-------PPEVPEAPK 10586
Query: 609 SLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPS 668
+ + + + + + + + A P + V PP + V P +P
Sbjct: 10587 EVVPEKKVPA-------APPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPE 10639
Query: 669 LGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPG 728
+ P +P P P PP P+ P P P P Q P
Sbjct: 10640 VPKVAVPEKK--VPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPP 10697
Query: 729 QQPPP-------LAQPTPLPQVLAPQ---PVVPLQPVP--------------PHLPPYLA 764
++P P +A+ LP V P+ VVP + VP P +P +
Sbjct: 10698 KKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV 10757
Query: 765 PASQVGAPA--QLKPLQMPQAPLQPLAQVPPQMP-------------------------- 796
P +V P ++ P ++P+ P +P+ + P +P
Sbjct: 10758 PEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIA 10817
Query: 797 -----PIPVVPPITPLAGIDGLPPALPDLPTATVP----PV------PPPQYFSPAVIL- 840
P+PV P + PPA+P+ P +P PV PPP+ P ++
Sbjct: 10818 PEEEKPVPVAEEEEP----EVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIE 10873
Query: 841 -PSLAAPLPPASPALPLQAVK-------------LPHPPGAPLAMPCRTI-VPNAPATI- 884
P L PP PA P + VK +P P P + + VP +
Sbjct: 10874 KPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVR 10933
Query: 885 PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQM--------APTDVPPSPHHTVQNMR 936
LL P + +V + + P P+ P PP P V+
Sbjct: 10934 KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT 10993
Query: 937 ATPPQPALPPQPTLPPQ--PVLP-PQPTLPPQPVLPPQPTRPPQPVLPPQPMLPP--QPV 991
T + + P+PT P+ P +P P P P+P + +PP P P+ P PV
Sbjct: 10994 VTKRERKI-PEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPV 11052
Query: 992 LPPQ-PALPVRPEPLQPHLPEQAAPAATP 1019
+ + A + E +P P + P TP
Sbjct: 11053 VGKKAEAKAPKEEAAKPKGPIKGVPKKTP 11081
Score = 78.6 bits (192), Expect = 6e-14
Identities = 102/418 (24%), Positives = 161/418 (38%), Gaps = 67/418 (16%)
Query: 710 LPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQ---------PVVPLQPVPPHLP 760
+P P+P + APP + P +P VL P+ P VP +PVP
Sbjct: 9958 VPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKV 10017
Query: 761 PYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDL 820
P P +V AP P ++P+ P +P VP + P+P ++ P +P++
Sbjct: 10018 PVPVP-KKVEAP----PAKVPEVPKKP---VPEKKVPVPAPKK------VEAPPAKVPEV 10063
Query: 821 PTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNA 880
P +P P P+P A P + K P P+A+P V
Sbjct: 10064 PKKLIPEEKKP-------------TPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFE 10110
Query: 881 PATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAP--TDVPPSPHHTVQNMRAT 938
+P V P L V LP + ++ P +VPP + +
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEV--LPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFV 10168
Query: 939 PPQPALPP-QPTLP-PQPVLPPQPTLPPQPVLPPQPTRPPQPVLP--PQPMLPPQPVLP- 993
P + LP +P +P P PV + + + V+ P+ P +P P+ + + +LP
Sbjct: 10169 PEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPK 10228
Query: 994 PQPALPVR--PEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQ-VPTVPVP----- 1045
+ LPV EP + + E+ P P + + P +V + VP P P
Sbjct: 10229 EEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKV 10288
Query: 1046 --PAAVLSPPLPEVLLP-------AAPELLPQFPSSLATVSASVQSVPTQTATLLPPA 1094
P A +S +PE +P A P +P+ P V VP + A +PPA
Sbjct: 10289 EAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKK---VPEKKVLVPKKEA--VPPA 10341
Score = 73.2 bits (178), Expect = 3e-12
Identities = 126/510 (24%), Positives = 181/510 (35%), Gaps = 125/510 (24%)
Query: 708 PVLPPPSTPMPTGPGQPAPPG----QQPPPLAQPTPLPQVLAPQPVVPLQPVPP------ 757
PV P P P+PT P APP + P P P+P+ L P P P P P
Sbjct: 9794 PVKPVPEEPVPTKP--KAPPAKVLKKAVPEEKVPVPIPKKLKPPP--PKVPEEPKKVFEE 9849
Query: 758 --HLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ--MPP--IPVVPP-------- 803
+ QV PA P++ + + VP + PP +P VP
Sbjct: 9850 KIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVA 9909
Query: 804 ---------------------------ITPLAGIDGLPPALPDLPTATVP----PVPPPQ 832
IT + +P +P++P VP PVP P+
Sbjct: 9910 FEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPK 9969
Query: 833 YFSPAVILPSLAAPLPPASP--ALPLQAVKLPHPPGAPLAMPCRTIVP--NAPATIPLLA 888
P P P P +P+ K PP A + + VP P +P
Sbjct: 9970 KKE----APPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKV 10025
Query: 889 VAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQP 948
APP + V ++P +PV P AP V P + + P+ +P
Sbjct: 10026 EAPP--------AKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPE---EKKP 10074
Query: 949 TLPPQPVLPPQPTLPPQPVLPPQPTRPPQ--PVLPPQPMLPPQPVLPPQPALPVRPEPLQ 1006
T P+ V P P +P + P P PQ VL + ++P + VLP + + E +
Sbjct: 10075 TPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVL 10134
Query: 1007 PH----LPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVP-----VPPAAVLSPPLPEV 1057
P LPE+ P +V + VP VP VL P+V
Sbjct: 10135 PEEEEVLPEEE-------------EIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV 10181
Query: 1058 LLPA-APELLPQ-------FPSSLATVSASVQSVP---TQTATLLPPANPPLPGGPGIAS 1106
+PA PE+ + P A V VP + +LP LP
Sbjct: 10182 PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLP------- 10234
Query: 1107 PCPTVQLTVEPVQEEQASQDKPPGLPQSCE 1136
V++T EP +EE S+++ P P S E
Sbjct: 10235 ----VEVTEEP-EEEPISEEEIPEEPPSIE 10259
Score = 61.2 bits (147), Expect = 1e-08
Identities = 93/393 (23%), Positives = 135/393 (34%), Gaps = 105/393 (26%)
Query: 797 PIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLP----PASP 852
PIPV P +P+ P T P PP + AV + P+P P P
Sbjct: 9792 PIPVKP--------------VPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPP 9837
Query: 853 ALPLQAVKL----------------PHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAA 896
+P + K+ P A + M + +V +P VAPP
Sbjct: 9838 KVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPP---- 9893
Query: 897 LSIHSAVAQLPGQPVYPAAFPQMAPTDV--------PPSPHHTVQNMRATPPQPALPPQ- 947
+ + +L + V AF + T V H + + P +P +
Sbjct: 9894 VRVPEVPKELEPEEV---AFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKV 9950
Query: 948 PTLPPQPV--------LPPQPTLPPQPVLPPQPTRPPQ--PVLPPQPMLPPQPVLPPQPA 997
P +P +PV +P + PP V P P +P + PVL P+ PP +P P
Sbjct: 9951 PEVPRKPVPEEKKPVPVPKKKEAPPAKV-PEVPKKPEEKVPVLIPKKEKPPPAKVPEVPK 10009
Query: 998 LPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDV-AAQVPTVPVPPAAVLSPPLPE 1056
PV PE+ P P P V+ A+VP VP P P+P
Sbjct: 10010 KPV---------PEEKVPV-----------PVPKKVEAPPAKVPEVPKKPVPEKKVPVPA 10049
Query: 1057 VLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVE 1116
P + A V VP + L+P P P + +P P V E
Sbjct: 10050 -------------PKKVEAPPAKVPEVPKK---LIPEEKKPTPVPKKVEAPPPKVPKKRE 10093
Query: 1117 PVQEEQASQDKPPGLPQSCESYGGSDVTSGKEL 1149
PV P LPQ E ++ +E+
Sbjct: 10094 PV-------PVPVALPQEEEVLFEEEIVPEEEV 10119
Score = 59.3 bits (142), Expect = 4e-08
Identities = 96/482 (19%), Positives = 172/482 (35%), Gaps = 70/482 (14%)
Query: 673 QQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPP 732
+ P P LP P P + + + PP+ +P P +P P ++P
Sbjct: 9283 EPPPKVPELPEKPAPEEVAPVPIPKK-----------VEPPAPKVPEVPKKPVPEEKKPV 9331
Query: 733 PLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVP 792
P+ + P P+ VP +PVP P + PA++ +Q + + V
Sbjct: 9332 PVPKKEPAAPPKVPE--VPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVT 9389
Query: 793 PQMPPIPVVPPITPLAGIDGLPPALPDLPTATVP----PVP-PPQYFSPAVILPSL-AAP 846
+ + PPA+P++P VP PVP + P +P+L P
Sbjct: 9390 QRE---------------ESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKP 9434
Query: 847 LPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAP-ATIPLLAVAPPGVAALSIHSAVAQ 905
+P A+P+ K PP A ++ +T+V L+ A P ++ H A+
Sbjct: 9435 VPEEKVAVPVPVAKKAPPPRAEVSK--KTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAE 9492
Query: 906 LPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQ 965
+ Y ++ + + T + P+ + + + + +
Sbjct: 9493 --EEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAE 9550
Query: 966 PVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILL 1025
P + T + + +P +P + PP +P P+ + +PE+ PA P + +
Sbjct: 9551 PA---EVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKI---VPEKKVPAPVPKKEKV- 9603
Query: 1026 GHPAPYAVDVAAQVPTVPVPPAAV-LSPPLP-------------EVLLPAAPELLPQFPS 1071
P + VP VPP + + PLP E +L A + + P
Sbjct: 9604 -PPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTK--KEAPP 9660
Query: 1072 SLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGL 1131
++VP + L P P P + V+EE+ S + P
Sbjct: 9661 KARVPEEPKRAVPEEKVLKLKPKREEEP-------PAKVTEFRKRVVKEEKVSIEAPKRE 9713
Query: 1132 PQ 1133
PQ
Sbjct: 9714 PQ 9715
Score = 57.4 bits (137), Expect = 2e-07
Identities = 103/466 (22%), Positives = 159/466 (34%), Gaps = 103/466 (22%)
Query: 743 VLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVP 802
+ P+ +P++PVP P KP P L+ VP + P+P+
Sbjct: 9786 ITEPEKPIPVKPVPEE-------------PVPTKPKAPPAKVLK--KAVPEEKVPVPIPK 9830
Query: 803 PITPLAGIDGLPPALPDLPTATVPP---VPPPQYFSPAVILPSLAAPLPPASPALPLQAV 859
+ P PP +P+ P + + V P+ P+ P + + V
Sbjct: 9831 KLKP------PPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKP-KRVVAEEKV 9883
Query: 860 KLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQ---------- 909
+P AP P R VP P + VA + + + +
Sbjct: 9884 PVPRKEVAP---PVR--VPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFIT 9938
Query: 910 -----PVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQ--PVLPPQPTL 962
PV P P++ VP + P +P P P + PVL P+
Sbjct: 9939 EEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEK 9998
Query: 963 PPQPVLPPQPTRP-PQ---PVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPE--QAAPA 1016
PP +P P +P P+ PV P+ + P +P P PV + + P+ +A PA
Sbjct: 9999 PPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPA 10058
Query: 1017 ATPGSQILL----GHPAPYAVDVAAQVPTVP------------------------VPPAA 1048
P L P P V A P VP VP
Sbjct: 10059 KVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEE 10118
Query: 1049 VLSP-----PLPEVLLPAAPELLP---QFPSSLATVSASVQSVPTQ-----TATLLPPAN 1095
VL P E +LP E+LP + P V + VP + +LP
Sbjct: 10119 VLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVK 10178
Query: 1096 PPLPGGPGIASPCPTVQLTVEP-----VQEEQASQDKPPGLPQSCE 1136
P +P + +P P ++ V ++E+A K P +P+ E
Sbjct: 10179 PKVP----VPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVE 10220
Score = 53.5 bits (127), Expect = 2e-06
Identities = 72/314 (22%), Positives = 117/314 (37%), Gaps = 54/314 (17%)
Query: 829 PPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLA 888
PPP P VI + + S + + V++ P + IVP P+ P+
Sbjct: 9175 PPP----PKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVS-----KKIVPQKPSRTPVQE 9225
Query: 889 VAPPGVAALSIHSAVAQLPGQPVYPAAF---------PQMAPTDVPPSPHHTVQNMRATP 939
V ++H+ + + ++ A+ P++ V H + R P
Sbjct: 9226 EVIE-VKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEP 9284
Query: 940 PQ--PALPPQPT------LP-PQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP 990
P P LP +P +P P+ V PP P +P P P + P PV +P PP+
Sbjct: 9285 PPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKV 9344
Query: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVL 1050
P+ +P P+ ++A PA P ++ G + + Q P PPA
Sbjct: 9345 PEVPKKPVPEEKIPVPVAKKKEAPPAKVP--EVQKGVVTEEKITIVTQREESP-PPAV-- 9399
Query: 1051 SPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGP----GIAS 1106
P +P+ +P + +P+ + VP PP P LP P +A
Sbjct: 9400 -PEIPKKKVPEERKPVPR----------KEEEVPP------PPKVPALPKKPVPEEKVAV 9442
Query: 1107 PCPTVQLTVEPVQE 1120
P P + P E
Sbjct: 9443 PVPVAKKAPPPRAE 9456
Score = 52.8 bits (125), Expect = 4e-06
Identities = 91/420 (21%), Positives = 150/420 (35%), Gaps = 55/420 (13%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPP--EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPS 1374
P P + PE+ PP P S P E ++ A + E+P A Q+
Sbjct: 10641 PKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKP 10700
Query: 1375 NPPGAPPAPLA--PSSPPVTA--LPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSEL 1430
P PA +A P PPV +P++ + P A A P P+ + E
Sbjct: 10701 VPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEK 10760
Query: 1431 ETSQPLAETHEAPLAVQPLV-----VGLAPCTPAPEAASTR--------DASAPREPLPP 1477
+ + P + E P A P V + P P PE A + + AP E + P
Sbjct: 10761 KVAVP--KKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAP 10818
Query: 1478 PAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLP---SPPLGPTVPPQPPSALES- 1533
+P P + +P + P P +P + + ++P P P P+P +E
Sbjct: 10819 EEEKPVPVAEEEEPEV--PPPAVPEEPKKI-IPEKKVPVIKKPEAPPPKEPEPEKVIEKP 10875
Query: 1534 --DGEGPPPRVGFVDSTIKSLDEKLRTLLYQE-----HVPTSSASAGTPVEVGDRDF-TL 1585
PPP +K +L+ + ++ VP V G++ L
Sbjct: 10876 KLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKL 10935
Query: 1586 EPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMT 1645
P R +P+ EV V K + R + +P VE +L + + +
Sbjct: 10936 LPERKPEPKEEV---------VLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPV 10986
Query: 1646 AESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPP 1705
E ++ +R + + P++P P EP + EA + +PPP
Sbjct: 10987 EEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAP--------EPKPKP--EAEVKTIKPPP 11036
Score = 52.4 bits (124), Expect = 5e-06
Identities = 132/616 (21%), Positives = 206/616 (33%), Gaps = 79/616 (12%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376
P A P PE+P P + PE +AP K + + + + + P P
Sbjct: 10567 PEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPP 10626
Query: 1377 PGAPPAP--LAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQ 1434
P P P P P V A+P+ A PE + E+ +
Sbjct: 10627 PKKPEVPPTKVPEVPKV-AVPEKKVPEAIPPKPESPPPEVFEE---------PEEVALEE 10676
Query: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPS-PHSGTPQPAL 1493
P AE E P P V + P P PE + A ++P PP P P P+ +
Sbjct: 10677 PPAEVVEEPEPAAPPQVTVPPKKPVPEKKA--PAVVAKKPELPPVKVPEVPKEVVPEKKV 10734
Query: 1494 GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLD 1553
P P A A ++P P V P+ A+ E PP +V V
Sbjct: 10735 PLVVPKKPEAPPA------KVPEVP--KEVVPEKKVAVPKKPEVPPAKVPEV-------- 10778
Query: 1554 EKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSE--VCGGDLALPPVPKEA 1611
K L + VP + P EV + + P P E V + P VP A
Sbjct: 10779 PKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPA 10838
Query: 1612 VSGRVQ--LPQ---PLVEKSELAPTRGAVMEQGTSS-SMTAESSPRSMLGYDRDGRQVAS 1665
V + +P+ P+++K E P + E+ + P D ++
Sbjct: 10839 VPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIF 10898
Query: 1666 DSHVVP--SVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGA 1723
+P VP+ P + P GGE P P+
Sbjct: 10899 QLKAIPKKKVPEK-PQVPEKVELTPLKVPGGEKKVRKLLP-----------ERKPEPKEE 10946
Query: 1724 RALGSP-RKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSP 1782
L S RKRPE+++ K + + + + PP E P
Sbjct: 10947 VVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPE--------------PPPPKPVEEVEVP 10992
Query: 1783 DVKLAVRRAQTASSI-EVGVGEPVSSDSGDEGPRA-----RPPVQKQASLPVSGSVAGDF 1836
V R+ + + E+ P+ + P A +PP + P++ V
Sbjct: 10993 TVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPV 11052
Query: 1837 V-KKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKK 1895
V KKA A + A GP G+ T S + S + ++A
Sbjct: 11053 VGKKAEAKAPKEEAAKPKGPIK----GVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTY 11108
Query: 1896 ELQSLREKHLKEISEL 1911
+L+++ K +KEI ++
Sbjct: 11109 QLKAVPLKFVKEIKDI 11124
Score = 48.9 bits (115), Expect = 5e-05
Identities = 158/751 (21%), Positives = 241/751 (32%), Gaps = 129/751 (17%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSS-----KEQPSFLASQQL-LSQ 1370
PV E P P P++ P L PE + P +L E+P + +++ +S
Sbjct: 9797 PVPEEPVPTKPKAPPAKVLKKAVPE-EKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISI 9855
Query: 1371 AGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSEL 1430
PA P P A +P P A P P+ L E
Sbjct: 9856 TKREKEQVTEPAAKVPMKPK--------RVVAEEKVPVPRKEVAPPVRVPEVPKELEPEE 9907
Query: 1431 ETSQPLAETH---------------EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPL 1475
+ TH E + VV + P PE PR+P+
Sbjct: 9908 VAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIP-VKVPE--------VPRKPV 9958
Query: 1476 P-PPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQP------P 1528
P P P P PA P P V + + P P P VP +P P
Sbjct: 9959 PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVP 10018
Query: 1529 SALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPL 1588
+ E PP +V V K + EK + VP P +V + L P
Sbjct: 10019 VPVPKKVEAPPAKVPEVPK--KPVPEK------KVPVPAPKKVEAPPAKVPEVPKKLIP- 10069
Query: 1589 RGDQPRSEVCGGDLALPPVPK--EAVSGRVQLPQP----------------------LVE 1624
+P + P VPK E V V LPQ L E
Sbjct: 10070 EEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPE 10129
Query: 1625 KSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPA 1684
+ E+ P V+ + E P Y + + + V+P V VP
Sbjct: 10130 EEEVLPEEEEVLPEEEEIPPEEEEVPPEE-EYVPEEEEFVPEEEVLPEVKPKVPVPAPVP 10188
Query: 1685 RVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPR----------KRPE 1734
++ + E PP+ + V P+ + + + P+ + PE
Sbjct: 10189 EIKKKVTEKKVVIPKKEEAPPAKVPEV------PKKVEEKRIILPKEEEVLPVEVTEEPE 10242
Query: 1735 QQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTA 1794
++ +S S+ ++ P ++ + P EAP+ K+ A+ +
Sbjct: 10243 EEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVP------EAPTPVPKKVEAPPAKVS 10296
Query: 1795 SSI-EVGVGEPVSSDSGDEGPRARPP-------------VQKQASLPVSGSVAGDFVKKA 1840
I E V PV E P A+ P +K+A P G + K +
Sbjct: 10297 KKIPEEKVPVPVQK---KEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLE-EKVS 10352
Query: 1841 TAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQSL 1900
AF Q L E ++P FH Y E+E+ IK E +
Sbjct: 10353 VAFRQEVVVKERLELEVVEAEVEEIP--EEEEFHEVEEYFEEGEFHEVEEF-IKLEQHRV 10409
Query: 1901 REKHLKEISE--LQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGK 1958
E+H E ++ + +E+E + P P + PP K K K
Sbjct: 10410 EEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEIS-EKIIPPKKPPTKVVPRKEPPAK 10468
Query: 1959 LLNPLVRQLKVVASSTGHLADSSRGPPAKDP 1989
+ P V + K+V + + R PP K P
Sbjct: 10469 V--PEVPK-KIVVEEKVRVPEEPRVPPTKVP 10496
Score = 46.2 bits (108), Expect = 4e-04
Identities = 81/399 (20%), Positives = 130/399 (32%), Gaps = 78/399 (19%)
Query: 1315 ICPVAEHPAPEAPESSPPLPLSSLPPEASQDS---APYKDQLSSKEQPSFLASQQLLSQ- 1370
I P + P P PP + +P + + P + ++ + P L ++++ +
Sbjct: 10449 IIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEK 10508
Query: 1371 ---AGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427
P+ P APP P V P++ +P P P P+
Sbjct: 10509 KVPVPPAKKPEAPP-------PKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAV 10561
Query: 1428 SELETSQ--------PLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPRE------ 1473
E + + P E EAP V P A PE + AP+E
Sbjct: 10562 PEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKK 10621
Query: 1474 -PLPPP-----------------APEPS-PHSGTPQPALGQP------------APLLPA 1502
P+PPP PE P + P+P P P
Sbjct: 10622 VPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEV 10681
Query: 1503 AVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQ 1562
A Q+ PP P + P+ + E PP +V V + ++K+ ++ +
Sbjct: 10682 VEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVP-EKKVPLVVPK 10740
Query: 1563 EHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKE---------AVS 1613
+ + P EV P + + P ++V P VPK+ V
Sbjct: 10741 KPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKV-------PEVPKKPVLEEKPAVPVP 10793
Query: 1614 GRVQLPQPLV--EKSELAPTRGAVMEQGTSSSMTAESSP 1650
R + P P V E E+AP E+ + E P
Sbjct: 10794 ERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEP 10832
Score = 45.8 bits (107), Expect = 5e-04
Identities = 210/1107 (18%), Positives = 355/1107 (32%), Gaps = 214/1107 (19%)
Query: 480 VEDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALI 539
V P ++ PK+ E F+ E T E E + HE + I + + V +I
Sbjct: 9890 VAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEV---VPVI 9946
Query: 540 QWRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLL 599
+ + P+E++ V P K PP + P P++PE +L
Sbjct: 9947 PVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKV--------------PEVPKKPEEKVPVL 9992
Query: 600 --------PPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCV 651
P +P + V + + P PA
Sbjct: 9993 IPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKK 10052
Query: 652 CSPPVSEGPVLPQSLPSLGAYQQPTAAPG--------LPVGSVPAP---ACPPSLQQHFP 700
P ++ P +P+ L + ++PT P +P P P A P + F
Sbjct: 10053 VEAPPAKVPEVPKKL--IPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFE 10110
Query: 701 DPAMSFAPVLPPPSTPMPTGPG------QPAPPGQQPPPLAQPTPLPQVLAPQP------ 748
+ + VLP +P + P ++ PP + P + P+
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170
Query: 749 ------VVPLQPVPPHLPPY---------LAPASQVGAPAQLK----------------- 776
V P PVP +P + P + PA++
Sbjct: 10171 EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEE 10230
Query: 777 ---PLQMPQAPLQ-PLAQ--VPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPP 830
P+++ + P + P+++ +P + P I V + P + + A+P+ PT PVP
Sbjct: 10231 EVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPT----PVPK 10286
Query: 831 PQYFSPAVI---LPSLAAPLP----PASPA--------LPLQAVKLPHPPGAPLAMPCRT 875
PA + +P P+P A PA +P + V +P P A
Sbjct: 10287 KVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTV 10346
Query: 876 IVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTD-------VPPSP 928
+ V + + + V ++P + + + +
Sbjct: 10347 LEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQ 10406
Query: 929 HHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPP 988
H + R + + + + +P PP+ + ++PP+ PP
Sbjct: 10407 HRVEEEHRVEKVHRVI--------EVFEAEEVEVFEKPKAPPKGPEISEKIIPPKK--PP 10456
Query: 989 QPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVP-VPPA 1047
V+P R EP PA P P V+ +VP P VPP
Sbjct: 10457 TKVVP-------RKEP----------PAKVPEV------PKKIVVEEKVRVPEEPRVPPT 10493
Query: 1048 AVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASP 1107
V PEVL P E++P+ + VP +PPA P P +
Sbjct: 10494 KV-----PEVLPPK--EVVPE------------KKVP------VPPAKKPEAPPPKV--- 10525
Query: 1108 CPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAA 1167
P V P ++ K P +P + K++ ++ E A
Sbjct: 10526 -PEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEA 10584
Query: 1168 RKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPD- 1226
K + + + +P +T + K+ E E K V + P
Sbjct: 10585 PKEVVPEKKVPAAPPK--KPEVTPV-------KVPEAPKEVVPEKKVPVPPPKKPEVPPT 10635
Query: 1227 ---EIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRGSDPGTSPPHLSTC 1283
E+ V + +A +V ++ E++ E+ A+ +P + P T
Sbjct: 10636 KVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT- 10694
Query: 1284 GLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEAS 1343
+ + + +A A V ++ L K V E P PE PL + PEA
Sbjct: 10695 -VPPKKPVPEKKAPAVVAKKPELPPVK-------VPEVPKEVVPEKKVPLVVPK-KPEAP 10745
Query: 1344 QDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPAT 1403
P ++ + P + + P+ P P P+ P V +P+ +P
Sbjct: 10746 PAKVP---EVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVP-VPERAESPPP 10801
Query: 1404 STMPEPASGTASQAGGPGT--PQGLTSELETSQPLAETHEAPLAVQP--------LVVGL 1453
EP + P P + E E P E P + P
Sbjct: 10802 EVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAP 10861
Query: 1454 APCTPAPEAASTRDASAPREPLPPPAP 1480
P P PE + PR P PPPAP
Sbjct: 10862 PPKEPEPEKVIEKPKLKPRPPPPPPAP 10888
Score = 45.1 bits (105), Expect = 8e-04
Identities = 122/620 (19%), Positives = 214/620 (34%), Gaps = 86/620 (13%)
Query: 1428 SELETSQPLAETHEAPLAVQPLVVGLAP-CTPAPEAASTRDASAPREPLPPPAPEPSPHS 1486
+E E S + E + + + + V ++ P P+ + AP E P P P+
Sbjct: 9253 TEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPP 9312
Query: 1487 GTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQP------PSALESDGEGPPP 1540
P + P +P V + + +PP P VP +P P + E PP
Sbjct: 9313 APKVPEV--PKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPA 9370
Query: 1541 RVGFVDSTIKSLDEKLRTLLYQEHVPTSSA---------SAGTPVEVGDRDFTLEPLRGD 1591
+V V + + +EK+ + +E P + PV + + P
Sbjct: 9371 KVPEVQKGVVT-EEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPA 9429
Query: 1592 QPRSEVCGGDLALP-PVPKEAVSGRVQLPQPLV---------EKSELA-PTRGAVMEQGT 1640
P+ V +A+P PV K+A R ++ + V EK A P R V
Sbjct: 9430 LPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEV 9489
Query: 1641 SS----SMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVP--------AFVRPARVEP 1688
S+ S + E S+ Y + R+ ++ V + P + RVE
Sbjct: 9490 SAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEA 9549
Query: 1689 TDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRF 1748
+ E E P + + P A+ +P+K ++ V +P +
Sbjct: 9550 EPAEVTERQEKKIVLKPK----IPAKIEEPPP--AKVPEAPKKIVPEKKVPAPVPKKEKV 9603
Query: 1749 SVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSD 1808
+E P PP V E P K+ R Q +V V+
Sbjct: 9604 PPPKVPEEPKKPVPEK---KVPPKVIKMEEPL--PAKVTERHMQITQEEKV----LVAVT 9654
Query: 1809 SGDEGPRARPPVQKQASLP------VSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVG 1862
+ P+AR P + + ++P + + K T F +R + + E P R
Sbjct: 9655 KKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREP 9714
Query: 1863 MKVPTISVTSFHSQSSYISSDNDS--------ELEDADIK--KELQSLRE-KHLKEISEL 1911
+ +++ ++ + + S E E+ D K +E + E +E E
Sbjct: 9715 QPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEER 9774
Query: 1912 QSQQKQEIEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVA 1971
+ ++ +E E KP+P P +K K K+L V + KV
Sbjct: 9775 EYERYEEHEEYITEPEKPIP--------VKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPV 9826
Query: 1972 SSTGHLADSSRGPPAKDPAQ 1991
+ + PP K P +
Sbjct: 9827 P----IPKKLKPPPPKVPEE 9842
Score = 43.1 bits (100), Expect = 0.003
Identities = 123/581 (21%), Positives = 189/581 (32%), Gaps = 102/581 (17%)
Query: 960 PTLPPQPV-LPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT 1018
P +P V +P P R P P + PP P+L P P +P P + + ++A
Sbjct: 8935 PDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPE-EKKPPPKRIEVTKKAVKKD- 8992
Query: 1019 PGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPA-APELLPQFPSSLATVS 1077
A V A+ + V PP P L+PA APE++ VS
Sbjct: 8993 -------------AKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEII--------DVS 9031
Query: 1078 ASVQSVPTQTATLLPPANPPLPGGPGIASPC-------------PTVQLTVEPVQE--EQ 1122
+ + V T T P +L VEP E EQ
Sbjct: 9032 SKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQ 9091
Query: 1123 ASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQE 1182
++P E Y V + KE+ + E F EG+ + E
Sbjct: 9092 PYYEEPD------EDYEEIKVEAKKEVHEEWEEDFE----EGQEYYEREEGYDEGEEEWE 9141
Query: 1183 RASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAE 1242
A + R I E E+H K+ + P ++ V +
Sbjct: 9142 EAYQEREVI-------QVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSR 9194
Query: 1243 RETFIEQMKDVMDKAEDMLSEDTDADRGSDP------GTSPPHLSTCGLGTGEE------ 1290
R +E+ K + K ++ + P P + T + EE
Sbjct: 9195 R---MEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFAS 9251
Query: 1291 --SRQSQANAPVYQQNVLHTGKRWFIICPVAEHP--APEAPESSPPLPLSSLP-PEASQD 1345
+ P Q+ ++ K I E P PE PE P ++ +P P+ +
Sbjct: 9252 HTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEP 9311
Query: 1346 SAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPP-APLAPSSP-PVTALPQDGAAPAT 1403
AP ++ K P ++ P P APP P P P P +P
Sbjct: 9312 PAPKVPEVPKKPVP-----EEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIP-------- 9358
Query: 1404 STMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAA 1463
+P A A P +G+ +E E + + E+P P V P PE
Sbjct: 9359 --VPVAKKKEAPPAKVPEVQKGVVTE-EKITIVTQREESP----PPAVPEIPKKKVPE-- 9409
Query: 1464 STRDASAPREPLPPPAPEPS-PHSGTPQPALGQPAPLLPAA 1503
+ E +PPP P+ P P+ + P P+ A
Sbjct: 9410 ERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKA 9450
Score = 41.2 bits (95), Expect = 0.011
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
Query: 708 PVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPAS 767
P +P P+PT P + PP + PP +A P PL L P P +P P +
Sbjct: 8935 PDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPL---LLPTP-EEKKPPPKRIEVTKKAVK 8990
Query: 768 QVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITP 806
+ KP +M P + + + PP PP ++P P
Sbjct: 8991 KDAKKVVAKPKEM--TPREEIVKKPP--PPTTLIPAKAP 9025
Score = 35.8 bits (81), Expect = 0.48
Identities = 40/181 (22%), Positives = 65/181 (35%), Gaps = 22/181 (12%)
Query: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQP 70
P ++E A P + P K P P++ + V + + E P ++ E P P+
Sbjct: 10678 PAEVVEEPEPAAPPQVTVPPKK---PVPEK--KAPAVVAKKPELPPVKVPEVPKEVVPE- 10731
Query: 71 LQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPE------------- 117
++ L++ K + P P VA P P P PE
Sbjct: 10732 -KKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAV 10790
Query: 118 --PVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEE 175
P + P P+ E AP + P EE V +E+E P ++ PE+
Sbjct: 10791 PVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEK 10850
Query: 176 E 176
+
Sbjct: 10851 K 10851
Score = 34.7 bits (78), Expect = 1.1
Identities = 67/355 (18%), Positives = 127/355 (35%), Gaps = 57/355 (16%)
Query: 1296 ANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSS 1355
A P + ++ K+ + E P P+ P+ P+P+ P+ ++ +++++
Sbjct: 10058 AKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQ--EEEVLFEEEIVP 10115
Query: 1356 KEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTAS 1415
+E+ +++L + P P PP ++ P +PE
Sbjct: 10116 EEE-VLPEEEEVLPEEEEVLPEEEEVLPEEEEIPP----EEEEVPPEEEYVPE------- 10163
Query: 1416 QAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPL 1475
+ E V+P V AP + + + P++
Sbjct: 10164 -----------------EEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEE 10206
Query: 1476 PPPA--PEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALES 1533
PPA PE + L + +LP V T + P+ P+ P ++E
Sbjct: 10207 APPAKVPEVPKKVEEKRIILPKEEEVLPVEV------TEEPEEEPISEEEIPEEPPSIEE 10260
Query: 1534 DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQP 1593
E PPRV V K++ E + + P + S P E + + + P
Sbjct: 10261 VEEVAPPRVPEVIK--KAVPEAPTPVPKKVEAPPAKVSKKIPEE----KVPVPVQKKEAP 10314
Query: 1594 RSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRG-AVMEQGTSSSMTAE 1647
++V P VPK+ +V +P +K + P +G V+E+ S + E
Sbjct: 10315 PAKV-------PEVPKKVPEKKVLVP----KKEAVPPAKGRTVLEEKVSVAFRQE 10358
Score = 33.5 bits (75), Expect = 2.4
Identities = 36/143 (25%), Positives = 52/143 (36%), Gaps = 16/143 (11%)
Query: 28 EPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAE 87
E + AA P V E+ +E P + P P+ P+ +V + K
Sbjct: 10591 EKKVPAAPPKKPEVTPVKVPEAPKEVVPE-KKVPVPPPKKPEVPPTKVPEVPKV------ 10643
Query: 88 RARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEP------GPDPIAAAVETAPAPDG 141
P P A+ +P +P PE V +EP P+P A T P
Sbjct: 10644 ---AVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKP 10700
Query: 142 GPREEAAATVRKEDEGAAEAKPE 164
P ++A A V K+ E PE
Sbjct: 10701 VPEKKAPAVVAKKPELPPVKVPE 10723
Score = 33.1 bits (74), Expect = 3.1
Identities = 24/88 (27%), Positives = 32/88 (36%), Gaps = 15/88 (17%)
Query: 931 TVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP 990
T+Q R T PP+ P V P+ P+ V P+P+ P
Sbjct: 32649 TIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHP--------------K 32694
Query: 991 VLPPQPALPVRPEPLQPHLPEQAAPAAT 1018
+ P P E +Q HLP A P T
Sbjct: 32695 AVSPTETKPTPTEKVQ-HLPVSAPPKIT 32721
Score = 32.0 bits (71), Expect = 6.9
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 9/92 (9%)
Query: 708 PVLPP-PSTPMPTGPGQPAPPG----QQPPPLAQ-PTPLPQVLAPQPVVPLQPVPPHLPP 761
P +PP P + PT P A Q P P+ P+P+ V AP P P++ V P
Sbjct: 255 PRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTP-SPVRSVSPAARI 313
Query: 762 YLAPASQVGAPAQLKPLQMPQAPLQPLAQVPP 793
+P V +P ++ Q P +VPP
Sbjct: 314 STSPIRSVRSPLLMRKTQASTVATGP--EVPP 343
Score = 32.0 bits (71), Expect = 6.9
Identities = 33/159 (20%), Positives = 54/159 (33%), Gaps = 11/159 (6%)
Query: 29 PRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAER 88
P K P P++ VE+ + P + P + P P ++V + ++
Sbjct: 10013 PEEKVPVPVPKK------VEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK 10066
Query: 89 ARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
P P + P P P PV P + + E P + P EE
Sbjct: 10067 LIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEV 10126
Query: 149 -----ATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDD 182
+ +E+E E + P PEEE E++
Sbjct: 10127 LPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEE 10165
Score = 31.6 bits (70), Expect = 9.1
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 12/121 (9%)
Query: 931 TVQNMRATPPQPALP----PQPTLPPQPVLP---PQPTLPPQPVLPPQPTRPPQPVLPPQ 983
T + ++ P +P P PT+P + V P P PP P+L P P P P +
Sbjct: 8924 TTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPP--PKR 8981
Query: 984 PMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVP 1043
+ + V + +P+ + P P P L+ AP +DV+++ V
Sbjct: 8982 IEVTKKAVKKDAKKVVAKPKEMTPREEIVKKP---PPPTTLIPAKAPEIIDVSSKAEEVK 9038
Query: 1044 V 1044
+
Sbjct: 9039 I 9039
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 115 bits (288), Expect = 5e-25
Identities = 152/522 (29%), Positives = 195/522 (37%), Gaps = 100/522 (19%)
Query: 686 VPAPACPPSLQQHFPDPAMSFAPVLP---PPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQ 742
+ PA +Q P P + VLP P +TP PTG P Q PP + T + +
Sbjct: 1251 ISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVK 1310
Query: 743 VLAPQ-PVVPLQPVPPHLPPYLAPASQVGAPAQLKP---LQMPQAPLQPLAQVPPQMPPI 798
++ Q P L PVPP P P+S G PA L P L + P L MP
Sbjct: 1311 IVVRQAPRDGLTPVPPLAPAPRPPSS--GLPAVLNPRPTLTPGRLPTPTLGTARAPMPTP 1368
Query: 799 PVVPPITPL---------AGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPS--LAAPL 847
+V P+ L A G P P +P P SP I S LA+P+
Sbjct: 1369 TLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPAS-SPMPIPNSSPLASPV 1427
Query: 848 P-----PASPALPLQA-VKLPHPPGAPLAMPCR---TIVPNAPA-----TIPLLAVAP-- 891
P S +LP+ LP P APL +P T+ + PA T PL V P
Sbjct: 1428 SSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAA 1487
Query: 892 ------------PGVAALSIHSAVA------QLPGQP----------------VYPAAFP 917
P +AL++ A A Q PG P V PA P
Sbjct: 1488 PGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSP 1547
Query: 918 QMAPTDVPPSPHHTVQNMRATPPQPA----LPPQPTLPPQPVLPPQPTLPPQP-VLPPQP 972
+ P SP + N P PA L P + P P PQ +L P P
Sbjct: 1548 VLVPASALASPFPSAPN-----PAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSP 1602
Query: 973 TRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYA 1032
P L P P+L P P P A P P+ AP++TPG+ + P P
Sbjct: 1603 APP----LAPLPVLAPSPGAAPVLASSQTPVPVM-------APSSTPGTSLASASPVPAP 1651
Query: 1033 VDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP 1092
V A T + PA V S PLP PA+ + L P+ T+ S P+QT + L
Sbjct: 1652 TPVLAPSSTQTMLPAPVPS-PLPS---PASTQTLALAPALAPTLGG---SSPSQTLS-LG 1703
Query: 1093 PANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQS 1134
NP P S P L P Q + P G Q+
Sbjct: 1704 TGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQT 1745
Score = 95.1 bits (235), Expect = 7e-19
Identities = 139/525 (26%), Positives = 186/525 (35%), Gaps = 88/525 (16%)
Query: 560 SPDKARGPP--VPLQVQVTYHAQAGQPGPPEPEEPEADQH----------------LLPP 601
SP+ + P PL + H + PGP P + LP
Sbjct: 1382 SPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPI 1441
Query: 602 TLPTSATSLASDS-TFDSGQGSTVYSDSQSSQQSVM--LGSLADAAPSP---AQCVCSPP 655
++PT+ + AS T TV + + SV L + AAP P A SP
Sbjct: 1442 SVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPS 1501
Query: 656 VSEGPVLPQSLPSLGAYQQP----------TAAPGLPVGSVPAPACPPSLQQHFPDPAMS 705
S + + PSL + Q P + PGL S APAC P L PA +
Sbjct: 1502 ASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGL--NSTVAPACSPVLV-----PASA 1554
Query: 706 FAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQP-----TPLPQVLAPQPVVPLQPVPPHLP 760
A P P P AP LA P P +LAP P PL P+
Sbjct: 1555 LASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPL----- 1609
Query: 761 PYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDL 820
P LAP+ GA L Q P + P + + VP TP+ LP
Sbjct: 1610 PVLAPSP--GAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLP-- 1665
Query: 821 PTATVP-PVPPPQYFSPAVILPSLAAPLPPASPALPLQA----VKLPHPPGAPLAMPCRT 875
A VP P+P P + P+LA L +SP+ L + P P P +
Sbjct: 1666 --APVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASS 1723
Query: 876 IVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNM 935
+VP PA LA PP L ++ P P+ PA + V P+P HT+
Sbjct: 1724 LVP-TPAQTLSLAPGPP----LGPTQTLSLAPAPPLAPA-------SPVGPAPAHTLTLA 1771
Query: 936 RATPPQPALPPQP----TLPPQPVLPPQPTLPP--QPVLPPQPTRPPQPVLPPQPMLPPQ 989
A+ L P TL P PV PTL P L P P ++
Sbjct: 1772 PASSSASLLAPASVQTLTLSPAPV----PTLGPAAAQTLALAPASTQSPASQASSLVVSA 1827
Query: 990 PVLPPQPALPVRPEPLQPHLPE----QAAPAATPGSQILLGHPAP 1030
P P V P+ P+ ++ P + P + G P P
Sbjct: 1828 SGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRP 1872
Score = 88.2 bits (217), Expect = 8e-17
Identities = 152/576 (26%), Positives = 198/576 (34%), Gaps = 120/576 (20%)
Query: 662 LPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGP 721
LP+ S + AP P P + Q P V+ P P+ P
Sbjct: 964 LPRHRLSRRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVP 1023
Query: 722 GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQ-- 779
+P PPG + P P+PQVL +V P P L PAS+ P L PLQ
Sbjct: 1024 VRP-PPGPELSAQPTPGPVPQVLPASLMVSASPAGPP----LIPASRPPGPVLLPPLQPN 1078
Query: 780 ---MPQAPLQPLAQV-----PP-------QMPPIPVVPPITPLAGIDGLPPALPDLPTAT 824
+PQ PL + PP PP PV P G L L P T
Sbjct: 1079 SGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYT 1138
Query: 825 VPPVPPPQYFSPAVILPSLAAPLPPASP----ALPLQAVKLPHPPG---APLAMPCRTIV 877
PP + + A P P +P P +LP LA + V
Sbjct: 1139 FPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPV 1198
Query: 878 PNAPATIPL------------------LAVAPP-----GVAALSIHSAVAQLPGQPVYPA 914
NA + PL LAV P V L L QP + A
Sbjct: 1199 ANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVA 1258
Query: 915 AFPQMAPTDVPPSPHHTVQNMRATPPQP---ALP-PQPTLPPQPV-----------LPPQ 959
+APT P + +T P P +LP +PP V P+
Sbjct: 1259 LIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPR 1318
Query: 960 PTLPPQPVLPPQPTRPPQPVLP----PQPMLP----PQPVL------PPQPALPVRPEPL 1005
L P P L P P RPP LP P+P L P P L P P L VRP
Sbjct: 1319 DGLTPVPPLAPAP-RPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTL-VRPLLK 1376
Query: 1006 QPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPT---------VPVPPAAVLSPPLPE 1056
H P A+ PG+ AP + VP+ +P+P ++ L+ P+
Sbjct: 1377 LVHSPSPEVSASAPGA-------APLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSS 1429
Query: 1057 -VLLPAAPELLPQFPSSL---------------ATVSASVQSVPTQTATLLPPANPPLPG 1100
V +P + L P++L TVSAS ++ T L P P PG
Sbjct: 1430 TVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPG 1489
Query: 1101 GPGI----ASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
P + ASP + LT+ S + PG P
Sbjct: 1490 PPSLAPSGASPSASA-LTLGLATAPSLSSSQTPGHP 1524
Score = 80.1 bits (196), Expect = 2e-14
Identities = 152/577 (26%), Positives = 199/577 (34%), Gaps = 127/577 (22%)
Query: 640 LADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSV-PAPACPPSLQQH 698
L A+ P + P LPQ LPS T+ P P S+ P P P L
Sbjct: 1060 LIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLS-- 1117
Query: 699 FPDPAMSFAPVLPPPSTPMPTGPGQPAPPG-----------QQPPPLAQPTPLPQ--VLA 745
P P + +L P + P PG PP + PTP PQ +L+
Sbjct: 1118 -PAPPPGSSSLLKPLTVP----PGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILS 1172
Query: 746 PQPVVPLQPVPPHLPPYLA-----PASQVGAP----------------AQLKPLQMPQ-A 783
P L LA P + G AQ++ L + Q
Sbjct: 1173 PDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPR 1232
Query: 784 PLQ-------------PLAQVPPQMPPIPVVPPI---TPLAGIDGLPPALPDLPTATVPP 827
PLQ L P + I V P TP++ + P+ PT P
Sbjct: 1233 PLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLP 1292
Query: 828 -----VPPPQYFSPAVI--------------LPSLA-APLPPASPALPLQAVKLPHPPGA 867
VPP + V+ +P LA AP PP+S L AV P P
Sbjct: 1293 LAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSS---GLPAVLNPRPTLT 1349
Query: 868 PLAMPCRTI-VPNAPATIPLL---------------AVAPPGVAALSIHSAV---AQLPG 908
P +P T+ AP P L + + PG A L+I S + + LPG
Sbjct: 1350 PGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPG 1409
Query: 909 QPVYPAAFPQMAPTDVPPSPHHTVQNMRATP-PQPALPPQPTLPPQ--PVLPPQPTLPPQ 965
P P +P P S +V + P P P P P P+ P
Sbjct: 1410 PASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASG 1469
Query: 966 PVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP-VRPEPLQPHLPEQAAPAATPGSQIL 1024
P L T P PV+ P P P L P A P L + + TPG +L
Sbjct: 1470 PALLTSVTPPLAPVV---PAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLL 1526
Query: 1025 L----GHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1080
L H VA V VP +A+ SP P+AP P S LA S++
Sbjct: 1527 LAPTSSHVPGLNSTVAPACSPVLVPASALASP------FPSAPNPAPAQASLLAPASSAS 1580
Query: 1081 QSVPT--------QTATLLPPANPPLPGGPGIASPCP 1109
Q++ T QTA L P PPL P + +P P
Sbjct: 1581 QALATPLAPMAAPQTAILAPSPAPPLAPLP-VLAPSP 1616
Score = 70.1 bits (170), Expect = 2e-11
Identities = 135/595 (22%), Positives = 204/595 (34%), Gaps = 124/595 (20%)
Query: 567 PPVPLQVQVTYHAQAGQPG----PPEPEEPEADQHLL---------PPTLPTSATSLASD 613
PP P Q+ P PP P A L+ PP++P SA+ ++
Sbjct: 2485 PPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISAS--VTN 2542
Query: 614 STFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQ 673
+ + + + +S +S+ L S+A + S V PP PV + LP + +
Sbjct: 2543 LPLGLRPEAELCAQALASPESLELASVASSETSSLSLV--PPKDLLPVAVEILPV--SEK 2598
Query: 674 QPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPT----GPGQPAPPGQ 729
+ P P ++ A + P +Q PD A + P +P G PP
Sbjct: 2599 NLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSA 2658
Query: 730 -QPPPLAQP--------------TPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQ 774
PL +P TP PQ +V + P + + +PA+
Sbjct: 2659 ASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPAR 2718
Query: 775 LKPLQMPQAPLQPLAQVP--PQMPPIPVV----------------------------PPI 804
P + A ++ Q P PP P V +
Sbjct: 2719 -PPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTL 2777
Query: 805 TPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHP 864
P P P + + + P PP P PS + P PP P + + ++L
Sbjct: 2778 VPGVSETSASPGSPSVRSMSGPESSPP-IGGPCEAAPSSSLPTPPQQPFIARRHIELGVT 2836
Query: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDV 924
G N LLA+ PP AV + G+P P A V
Sbjct: 2837 GGGS--------PENGDGA--LLAITPP---------AVKRRRGRPPKKNRSPADAGRGV 2877
Query: 925 PPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQP 984
+P T++ T PV P+ + PVL PQ PQP L PQP
Sbjct: 2878 DEAPSSTLKGK-------------TNGADPVPGPETLIVADPVLEPQLIPGPQP-LGPQP 2923
Query: 985 MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044
+ P P+L P E + P +A PG+ G D ++ T P
Sbjct: 2924 VHRPNPLLSP-------VEKRRRGRPPKARDLPIPGTISSAG-------DGNSESRTQPP 2969
Query: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLP 1099
P + L+P P ++ P A +++ TV+ S P + PP NPP P
Sbjct: 2970 PHPSPLTPLPPLLVCPTA-----TVANTVTTVTISTS--PPKRKRGRPPKNPPSP 3017
Score = 68.2 bits (165), Expect = 9e-11
Identities = 216/942 (22%), Positives = 312/942 (33%), Gaps = 224/942 (23%)
Query: 926 PSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQP-TLPPQPVLPPQPTRPPQPVLP-PQ 983
P+P A PAL P P P P+ P P T+ P +LP P PP + P
Sbjct: 2439 PAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPP--PPSQIPPCSS 2496
Query: 984 PMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPA-ATPGSQILLGHPAPYAVDVAAQVPTV 1042
P P P P PA H P A TP S +LLG P +V ++A V +
Sbjct: 2497 PACTPPPACTPPPA----------HTPPPAQTCLVTPSSPLLLGPP---SVPISASVTNL 2543
Query: 1043 PV---PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLP 1099
P+ P A + + L A+PE L ASV S T + +L+PP + LP
Sbjct: 2544 PLGLRPEAELCAQAL------ASPESLE---------LASVASSETSSLSLVPPKD-LLP 2587
Query: 1100 GGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGG 1159
V + + PV E+ S P P G +E DS EG
Sbjct: 2588 -----------VAVEILPVSEKNLS--LTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLT 2634
Query: 1160 GRLEGRAARKHHRRSTRARSRQERAS-RPRLTILNVCNTGDKMVECQLETHNHKMVTFKF 1218
EG S AS P L T +++ E + T +
Sbjct: 2635 VLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSS-------- 2686
Query: 1219 DLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRGSDPGTSPP 1278
+ P E+ T V A S T + G P P
Sbjct: 2687 ---PEKPQELVTAEV----------------------AAPSTSSSATSSPEGPSPARPPR 2721
Query: 1279 HLSTC-----GLGTGEESRQSQANAP------------VYQQNVL------HTGKRWFII 1315
++ G GTG R Q P V ++ L G ++
Sbjct: 2722 RRTSADVEIRGQGTG---RPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLV 2778
Query: 1316 CPVAEHPAP---------EAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQ 1366
V+E A PESSPP+ P EA+ S+ L + Q F+A +
Sbjct: 2779 PGVSETSASPGSPSVRSMSGPESSPPI---GGPCEAAPSSS-----LPTPPQQPFIARRH 2830
Query: 1367 L-LSQAGPSNPPGAPPAPLAPSSPPVTAL----PQDGAAPATS--TMPEPASGTASQAGG 1419
+ L G +P A LA + P V P+ +PA + + E S T
Sbjct: 2831 IELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTN 2890
Query: 1420 PGTPQGLTSELETSQPLAETH----EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPL 1475
P L + P+ E PL QP+ +P + R A P+
Sbjct: 2891 GADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPI 2950
Query: 1476 P---------------PPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLG 1520
P P P PSP + P P L P + V V+++TS P
Sbjct: 2951 PGTISSAGDGNSESRTQPPPHPSPLTPLP-PLLVCPTATVANTVTTVTISTS--PPKRKR 3007
Query: 1521 PTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGD 1580
P PPS P ++ +D S+ E ++ + + E G
Sbjct: 3008 GRPPKNPPSP-------RPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGS 3060
Query: 1581 RDFT-LEPLR--GDQPRSEVCGGDLALPPVP-----KEAVSGRVQLPQPLVEKS-ELAPT 1631
R T L LR + R GG + + + ++ G ++L P+V + +L T
Sbjct: 3061 RPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTPKLRST 3120
Query: 1632 RGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDR 1691
R + + E PR G G P + R++P
Sbjct: 3121 R--LRPGSLVPPLETEKLPRKRAGAPVGGS----------------PGLAKRGRLQPPSP 3162
Query: 1692 DGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVV 1751
G E +E S G G+PR+RP P + VG
Sbjct: 3163 LGPEGSVEESEAEASGEEEEGD-------------GTPRRRP------GPRRLVG----T 3199
Query: 1752 STQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQT 1793
+ Q + + LR SAPP + + P V R+A+T
Sbjct: 3200 TNQGDQRI-----LRSSAPPSL------AGPAVSHRGRKAKT 3230
Score = 62.0 bits (149), Expect = 6e-09
Identities = 180/881 (20%), Positives = 280/881 (31%), Gaps = 168/881 (19%)
Query: 714 STPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPA 773
+TP P + P P P P AP + L PVP V AP
Sbjct: 2424 TTPPRCSPARERVPRPAPRPRPTPAS-----APAAIPALVPVP------------VSAPV 2466
Query: 774 QLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQY 833
P+ P + P PP +PP + PA P T PP P
Sbjct: 2467 ---PISAPNPITILPVHILPSPPPPSQIPPCS--------SPACTPPPACTPPPAHTPPP 2515
Query: 834 FSPAVILPSLAAPLPPASPALPLQAVKLPHPPG-APLAMPCRTIVPNAPATIPLLAVAPP 892
++ PS +PL P++P+ A P G P A C + +P ++ L +VA
Sbjct: 2516 AQTCLVTPS--SPLLLGPPSVPISASVTNLPLGLRPEAELCAQALA-SPESLELASVASS 2572
Query: 893 GVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPP 952
++LS+ +P + + P A + ++ +N+ TP P+L + P
Sbjct: 2573 ETSSLSL------VPPKDLLPVAVEILPVSE---------KNLSLTPSAPSLTLEAGSIP 2617
Query: 953 QPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQP---MLPPQPVLPPQPALPVRPEPLQPHL 1009
P L P P+ + LPP P+ + L
Sbjct: 2618 NGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEEL 2677
Query: 1010 PEQAAPAATPGSQ---ILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLL------- 1059
E P ++P + AP A P P P +V +
Sbjct: 2678 TEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGR 2737
Query: 1060 ---PAAPELLPQFPSSLATV--------------SASVQSVPTQTATLLPPANPPL---- 1098
P P++L + P L TV A+ VP + T P +P +
Sbjct: 2738 PGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMS 2797
Query: 1099 --PGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGA 1156
P I PC +S PP P + VT G ++ +GA
Sbjct: 2798 GPESSPPIGGPCEAA---------PSSSLPTPPQQPFIARRHIELGVTGGGS-PENGDGA 2847
Query: 1157 F------GGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHN 1210
R GR +K+ + R E S
Sbjct: 2848 LLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSS------------------------ 2883
Query: 1211 HKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQM-KDVMDKAEDMLSEDTDADR 1269
T K +G P ++ D +L+ + + + + + +LS R
Sbjct: 2884 ----TLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRR 2939
Query: 1270 GSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICP---VAEHPAPEA 1326
G P + G+ + +S+ P + + T ++CP VA
Sbjct: 2940 GRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPL--TPLPPLLVCPTATVANTVTTVT 2997
Query: 1327 PESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAP 1386
+SPP PP+ P + + ++ S L S L G P
Sbjct: 2998 ISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGL----------GRRRQPQGQ 3047
Query: 1387 SSPPVTALPQDGAAPAT--STMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPL 1444
++ +DG+ P T + + A G + G + + ++ LA++ L
Sbjct: 3048 GESEGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSM---VVAVIQDDLDLADSGPGGL 3104
Query: 1445 AVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAV 1504
+ P VV L P+ STR P +PP E P P G P
Sbjct: 3105 ELTPPVVSL-----TPKLRSTR--LRPGSLVPPLETEKLPRKRAGAPVGGSP-------- 3149
Query: 1505 GAVSLATSQLPSPPLGPTVPPQ----PPSALESDGEGPPPR 1541
G Q PS PLGP + S E +G+G P R
Sbjct: 3150 GLAKRGRLQPPS-PLGPEGSVEESEAEASGEEEEGDGTPRR 3189
Score = 60.5 bits (145), Expect = 2e-08
Identities = 127/544 (23%), Positives = 180/544 (33%), Gaps = 107/544 (19%)
Query: 642 DAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPG----LPVGSVPAPACPPSLQQ 697
+ P PA P S +P +P + P +AP LPV +P+P PP Q
Sbjct: 2434 ERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSP--PPPSQ- 2490
Query: 698 HFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQP---TPLPQVLAPQPVVPLQP 754
+PP S+P T P PP PP AQ TP +L P VP+
Sbjct: 2491 ------------IPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISA 2538
Query: 755 VPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLP 814
+LP L P +++ A A P + A + + + +VPP D LP
Sbjct: 2539 SVTNLPLGLRPEAELCAQALASPESLELASV-----ASSETSSLSLVPP------KDLLP 2587
Query: 815 PALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMP-- 872
A+ LP + L P++P+L L+A +P+ G P
Sbjct: 2588 VAVEILPVS------------------EKNLSLTPSAPSLTLEAGSIPN--GQEQEAPDS 2627
Query: 873 ----CRTIVPNAPATIPLLAVAPPGV----AALSIHSAVAQLPGQPVYPAAFPQMAPTDV 924
T++P +PL G+ +A S L PT
Sbjct: 2628 AEGTTLTVLPEG-EELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSS 2686
Query: 925 PPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT-RPPQPVLPP- 982
P P V A P + P P PP+ + Q T RP QP P
Sbjct: 2687 PEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKV 2746
Query: 983 QPMLPPQPVLPPQPALPVR--------PEPLQPHLPEQAAPAATPGSQILLGHPA----- 1029
LP + V + VR L P + E +A +P + + G +
Sbjct: 2747 LRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIG 2806
Query: 1030 -PYAVDVAAQVPTVPVPP--------AAVLSPPLPE----VLLPAAPELL-------PQF 1069
P ++ +PT P P V PE LL P + P+
Sbjct: 2807 GPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKK 2866
Query: 1070 PSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPP 1129
S A V P+ T P+PG P + +PV E Q P
Sbjct: 2867 NRSPADAGRGVDEAPSSTLKGKTNGADPVPG--------PETLIVADPVLEPQLIPGPQP 2918
Query: 1130 GLPQ 1133
PQ
Sbjct: 2919 LGPQ 2922
Score = 57.4 bits (137), Expect = 2e-07
Identities = 67/247 (27%), Positives = 98/247 (39%), Gaps = 39/247 (15%)
Query: 1329 SSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF---------------LASQQLLSQAGP 1373
+S P+P+ + P AS S+ LSS S +++ +S +GP
Sbjct: 1411 ASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGP 1470
Query: 1374 S-----NPPGAPPAPLAPSSPPVTALPQDGAAPATS--TMPEPASGTASQAGGPGTPQGL 1426
+ PP AP P AP P +L GA+P+ S T+ + + S + PG P L
Sbjct: 1471 ALLTSVTPPLAPVVPAAPGPP---SLAPSGASPSASALTLGLATAPSLSSSQTPGHPL-L 1526
Query: 1427 TSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP------------REP 1474
+ + P + AP LV A +P P A + A A P
Sbjct: 1527 LAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATP 1586
Query: 1475 LPP-PAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALES 1533
L P AP+ + + +P P L L P+ A LA+SQ P P + P+ P A S
Sbjct: 1587 LAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASAS 1646
Query: 1534 DGEGPPP 1540
P P
Sbjct: 1647 PVPAPTP 1653
Score = 52.8 bits (125), Expect = 4e-06
Identities = 95/395 (24%), Positives = 130/395 (32%), Gaps = 42/395 (10%)
Query: 603 LPTSATS-------LASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPP 655
LP SA S L +D T + + + S Q ++ +A APS + S P
Sbjct: 2654 LPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVA--APSTSSSATSSP 2711
Query: 656 VSEGPVLP---QSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM-------- 704
P P ++ + Q T PG P G P L + +
Sbjct: 2712 EGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQR 2771
Query: 705 SFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA 764
A L P + PG P+ P + P P AP +P PP P
Sbjct: 2772 GAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLP---TPPQQPFIAR 2828
Query: 765 PASQVGAPAQLKPLQMPQAPLQPLAQVPPQM------PPIPVVPPITPLAGIDGLPPALP 818
++G P A L A PP + PP P G+D P +
Sbjct: 2829 RHIELGVTGGGSPENGDGALL---AITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTL 2885
Query: 819 DLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVP 878
T PVP P+ V P L L P L Q V P+P +P+ R P
Sbjct: 2886 KGKTNGADPVPGPETL--IVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPP 2943
Query: 879 NAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRAT 938
A +P+ PG + + P +P+ + P V P+ TV N T
Sbjct: 2944 KA-RDLPI-----PGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTA--TVANTVTT 2995
Query: 939 PPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973
PP+ P PP P PVL T
Sbjct: 2996 VTISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDST 3030
Score = 52.0 bits (123), Expect = 6e-06
Identities = 131/564 (23%), Positives = 186/564 (32%), Gaps = 101/564 (17%)
Query: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPS--FL------ASQQLLSQAGP 1373
PA E E+ P A Q+ A +QL+ E+ + FL S++ L QA
Sbjct: 2278 PAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQA-- 2335
Query: 1374 SNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG-GPGTPQGLTSELET 1432
A L + V LPQ+ P +G S G G GT +
Sbjct: 2336 EEQVEAARKDLDQAKEEVFRLPQEEEEG-------PGAGDESSCGTGGGTHRRSKKAKAP 2388
Query: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP------REPLPPPAPEPSPHS 1486
+P E + G A TP A TR + P RE +P PAP P P
Sbjct: 2389 ERPGTRVSERLRGARAETQG-ANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRP-- 2445
Query: 1487 GTPQPALGQPAPLLPAAVGA----------VSLATSQLPSPPLGPTVPP-------QPPS 1529
TP A L+P V A L LPSPP +PP PP+
Sbjct: 2446 -TPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPA 2504
Query: 1530 ALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLR 1589
PPP + + L LL VP S++ P+
Sbjct: 2505 CTPPPAHTPPPAQTCLVTPSSPL------LLGPPSVPISASVTNLPL------------- 2545
Query: 1590 GDQPRSEVCGGDLALP-PVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAES 1648
G +P +E+C LA P + +V+ LV +L P ++ + S
Sbjct: 2546 GLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPS 2605
Query: 1649 SPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVE----PTDRDGGEAGESSAEPP 1704
+P L G P + V P E ++ +G E S+A
Sbjct: 2606 APSLTL---EAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDE 2662
Query: 1705 PSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHS 1764
P + S T SP K P++ + A S S+ + + A P
Sbjct: 2663 PLQEPLEADRTSEELTEAKTPTSSPEK-PQELVTAEVAAPSTSSSATSSPEGPSPARPPR 2721
Query: 1765 LRYSAPPDVY-----LDEAPSSPDV---------------KLAVRRAQ---TASSIEVGV 1801
R SA ++ P P V +L RR Q AS++ GV
Sbjct: 2722 RRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGV 2781
Query: 1802 GEPVSSDSGD-----EGPRARPPV 1820
E +S GP + PP+
Sbjct: 2782 SETSASPGSPSVRSMSGPESSPPI 2805
Score = 45.1 bits (105), Expect = 8e-04
Identities = 136/576 (23%), Positives = 197/576 (34%), Gaps = 93/576 (16%)
Query: 1322 PAPEAPESSPPLPLSSLP---------PEASQDSAPYKD--------QLSSKEQPSFLAS 1364
PAP P S P L+ P P AP +L P AS
Sbjct: 1329 PAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS 1388
Query: 1365 QQ---LLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPG 1421
L+ + P + P + P P + P + P A+P +ST+ P
Sbjct: 1389 APGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPL--ASPVSSTVSVP------------ 1434
Query: 1422 TPQGLTSELETSQPLAETHEAPLAVQPLVVGL-APCTPAPEAASTRDASAPREPLPPPAP 1480
L+S L S P T AP A PL + + AP T + + + P PL P P
Sbjct: 1435 ----LSSSLPISVP--TTLPAP-ASAPLTIPISAPLTVSASGPALLTSVTP--PLAPVVP 1485
Query: 1481 -EPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPP--LGPTVPPQPPSALESDGEG 1537
P P S P A + L A SL++SQ P P L PT
Sbjct: 1486 AAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPT--------------- 1530
Query: 1538 PPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEV 1597
S + L+ + VP S+ ++ P L S+
Sbjct: 1531 --------SSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQA 1582
Query: 1598 CGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYD 1657
LA P+ A+ P PL LAP+ GA +S + +P S
Sbjct: 1583 LATPLAPMAAPQTAILAPSPAP-PLAPLPVLAPSPGAAPVLASSQTPVPVMAPSS----- 1636
Query: 1658 RDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRD-GGEAGESSAEPPPSDMGTVGGQAS 1716
G +AS S V P P+ + P A + P+ T+GG +S
Sbjct: 1637 TPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGG-SS 1695
Query: 1717 HPQTLGARALGSPRKRPEQQDVS-SPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYL 1775
QTL + G+P+ Q +S +PA S+V T + +P P L
Sbjct: 1696 PSQTL-SLGTGNPQGPFPTQTLSLTPAS-----SLVPTPAQTLSLAPGP---PLGPTQTL 1746
Query: 1776 DEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRA-RPPVQKQASLPVSGSVAG 1834
AP+ P + A ++ + P SS + P + + A +P G A
Sbjct: 1747 SLAPAPPLAPASPVGPAPAHTLTLA---PASSSASLLAPASVQTLTLSPAPVPTLGPAAA 1803
Query: 1835 DFVKKATAFLQRP-SRAGSLGPETPSRVGMKVPTIS 1869
+ A A Q P S+A SL + V +S
Sbjct: 1804 QTLALAPASTQSPASQASSLVVSASGAAPLPVTMVS 1839
Score = 43.9 bits (102), Expect = 0.002
Identities = 102/476 (21%), Positives = 153/476 (32%), Gaps = 53/476 (11%)
Query: 1408 EPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQ-PLVVGLAPCTPAPEAASTR 1466
+PA QA P S L +S P T AP + PL P T +
Sbjct: 1253 QPAHVALIQAVAPTPGPTPVSVLPSSTP--STTPAPTGLSLPLAANQVPPTMVNNTGVVK 1310
Query: 1467 DA--SAPRE---PLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGP 1521
APR+ P+PP AP P P P+ G PA L P +L +LP+P LG
Sbjct: 1311 IVVRQAPRDGLTPVPPLAPAPRP------PSSGLPAVLNPRP----TLTPGRLPTPTLGT 1360
Query: 1522 TVPPQPPSALESD----GEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTS-SASAGTPV 1576
P P L P P V L T+ HVP+S A +P+
Sbjct: 1361 ARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPL-----TISSPLHVPSSLPGPASSPM 1415
Query: 1577 EVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVM 1636
P+ P + +++P +S LP P + + +
Sbjct: 1416 ----------PIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTV 1465
Query: 1637 EQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEA 1696
+ +T+ + P + + G + S PS + + G
Sbjct: 1466 SASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPL 1525
Query: 1697 GESSAEPPPSDMGTVGGQASHPQTLGARALGS-----PRKRPEQQDVSSPAKTVGRFSVV 1751
+ + + A P + A AL S P P Q + +PA + +
Sbjct: 1526 LLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALAT 1585
Query: 1752 STQDEWTLASPHSLRYS---APPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEP-VSS 1807
+A+P + + APP L SP + +QT + P S
Sbjct: 1586 PLA---PMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSL 1642
Query: 1808 DSGDEGPRARP---PVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSR 1860
S P P P Q LP P+ A +LG +PS+
Sbjct: 1643 ASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQ 1698
Score = 40.4 bits (93), Expect = 0.020
Identities = 180/865 (20%), Positives = 274/865 (31%), Gaps = 108/865 (12%)
Query: 1374 SNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETS 1433
+ P P + P+S V+A P S P P Q PQ L S L
Sbjct: 1034 AQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGV- 1092
Query: 1434 QPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPAL 1493
L+ T P + L P PAP S P PPP S +P
Sbjct: 1093 --LSGTSRPPTP----TLSLKPTPPAPVRLS---------PAPPPG-----SSSLLKPLT 1132
Query: 1494 GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLD 1553
P P A + T+ + P P P + S P + + S+
Sbjct: 1133 VPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILS----PDMQARLPSGEVVSIG 1188
Query: 1554 EKLRTLLYQEHVPTSSASAGTPVEVGDRDFTL-------------EPLRGDQPRSEVCGG 1600
+ L Q V + S ++ TL PL+ + GG
Sbjct: 1189 Q--LASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGG 1246
Query: 1601 DLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDG 1660
L P + P P PT +V+ T S+ A + L ++
Sbjct: 1247 QHHLISQPAHVALIQAVAPTP-------GPTPVSVLPSSTPSTTPAPTGLSLPLAANQVP 1299
Query: 1661 RQVASDSHVVPSVPQDVP--AFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHP 1718
+ +++ VV V + P + P R + P P+ G+ P
Sbjct: 1300 PTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPT---LTPGRLPTP 1356
Query: 1719 QTLGARALGSPRK---RPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYL 1775
TLG P RP + V SP+ V + + T++SP + S P
Sbjct: 1357 -TLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAA--PLTISSPLHVPSSLP----- 1408
Query: 1776 DEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARP-----PVQKQASLPVSG 1830
P+S + + + AS + V P+SS P P P+ S P++
Sbjct: 1409 --GPASSPMPIP-NSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTV 1465
Query: 1831 SVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSELED 1890
S +G + + P + GP + + G ++T + + +SS
Sbjct: 1466 SASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPG--- 1522
Query: 1891 ADIKKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLP--PNVGFFHTAPPTGRRRK 1948
L + H+ ++ + + L P P PN P +
Sbjct: 1523 ---HPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPN-------PAPAQASL 1572
Query: 1949 TSKSKLKAGKLLNPLVRQLKVVASSTGHLADSSRGPPAKDPAQASVGLTADSTGLSGKAV 2008
+ + + L PL + A T LA P+ P A + + A S G +
Sbjct: 1573 LAPASSASQALATPLA---PMAAPQTAILA------PSPAPPLAPLPVLAPSPGAAPVLA 1623
Query: 2009 QTQQPCSVRASLSSDICSGLASDGGGARGQGWTVYHPTSERVTYKSSSKPRARFLSGPVS 2068
+Q P V A S+ G + V P+S T P L P S
Sbjct: 1624 SSQTPVPVMAPSST---PGTSLASASPVPAPTPVLAPSS---TQTMLPAPVPSPLPSPAS 1677
Query: 2069 VSIWSALKRLCLGKEHSSRSSTSSLAPGPEPGPQPALHVQAQVNNSNNKKGTFTDDLHKL 2128
+ L SS S T SL G GP P + +S T L
Sbjct: 1678 TQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPG 1737
Query: 2129 VDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEARAMTAPRAGVGMPRLPPA 2188
++T+ A P L + A AP + A A V L PA
Sbjct: 1738 PPLGPTQTLSLAPAPP----LAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPA 1793
Query: 2189 PGPLSTTVIPGAAPTLSVPTPDPES 2213
P P T+ P AA TL++ +S
Sbjct: 1794 PVP---TLGPAAAQTLALAPASTQS 1815
Score = 37.7 bits (86), Expect = 0.13
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 12/123 (9%)
Query: 21 AGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGL-EAAEAPGPQPPQPLQRRVLLLC 79
A P+ + + P P R RR + G + PGP+ + L R++ +
Sbjct: 2699 AAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVV 2758
Query: 80 KTRRLIAERARGRPAA----PAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVET 135
+ + L+ R + R AA P + A PG+P + +GPE PI E
Sbjct: 2759 EEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPE-------SSPPIGGPCEA 2811
Query: 136 APA 138
AP+
Sbjct: 2812 APS 2814
Score = 36.2 bits (82), Expect = 0.37
Identities = 64/267 (23%), Positives = 81/267 (30%), Gaps = 61/267 (22%)
Query: 584 PGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADA 643
PGPP PP P S A T S SS + S+
Sbjct: 1736 PGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPAS-------SSASLLAPASVQTL 1788
Query: 644 APSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA--APGLPVGSVPAPACPPSLQQHFP- 700
SPA P + GP Q+L A Q A A L V + A P ++ P
Sbjct: 1789 TLSPA-----PVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPV 1843
Query: 701 --DPAMSFAPVLPPPSTPMP-TGPGQPAPPGQQPPPLAQPTPLPQV-------------- 743
D + PPS P T G P P Q PPP P L +
Sbjct: 1844 SKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERLER 1903
Query: 744 -----------------------LAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQM 780
PQPV P+ P P P A + +
Sbjct: 1904 IFQLSEAHGALAPVYGTEVLDFCTLPQPVA--SPIGPRSPGPSHPTFWTYTEAAHRAVLF 1961
Query: 781 PQAPLQPLAQVPPQ----MPPIPVVPP 803
PQ L L+++ + MPP+ PP
Sbjct: 1962 PQQRLDQLSEIIERFIFVMPPVEAPPP 1988
Score = 36.2 bits (82), Expect = 0.37
Identities = 60/242 (24%), Positives = 81/242 (33%), Gaps = 33/242 (13%)
Query: 552 PKEQQDVGSP-DKARGPPVPLQVQVTY----HAQAGQPGPPEPEEPEADQHLLPPTLPT- 605
P+ +G P + A +P Q + H + G G PE D LL T P
Sbjct: 2799 PESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPEN--GDGALLAITPPAV 2856
Query: 606 ----SATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSL--ADAAPSPAQCVCSPPVSEG 659
+ S D+G+G + S + G AD P P + + PV E
Sbjct: 2857 KRRRGRPPKKNRSPADAGRGV------DEAPSSTLKGKTNGADPVPGPETLIVADPVLEP 2910
Query: 660 PVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPT 719
++P P LG QP P P P ++ P A LP P T
Sbjct: 2911 QLIPGPQP-LGP--QPVHRPN--------PLLSPVEKRRRGRPPK--ARDLPIPGTISSA 2957
Query: 720 GPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQ 779
G G Q PP + TPLP +L V P + G P + P
Sbjct: 2958 GDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSP 3017
Query: 780 MP 781
P
Sbjct: 3018 RP 3019
Score = 34.7 bits (78), Expect = 1.1
Identities = 53/221 (23%), Positives = 76/221 (34%), Gaps = 52/221 (23%)
Query: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPP 1381
PA + P P+ +L P A+Q A +S + P+ AS ++S +G + P
Sbjct: 1782 PASVQTLTLSPAPVPTLGPAAAQTLALAP---ASTQSPASQASSLVVSASGAAPLPVTMV 1838
Query: 1382 APL--------------APSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427
+ L P SPP TA G P P P S + + +
Sbjct: 1839 SRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRS 1898
Query: 1428 SELETSQPLAETHEAPLAV------------QPLVVGLAPCTPAPE--------AASTRD 1467
LE L+E H A V QP+ + P +P P A+ R
Sbjct: 1899 ERLERIFQLSEAHGALAPVYGTEVLDFCTLPQPVASPIGPRSPGPSHPTFWTYTEAAHRA 1958
Query: 1468 ASAPREPL---------------PPPAPEPSPHSGTPQPAL 1493
P++ L P AP PS H+ P P L
Sbjct: 1959 VLFPQQRLDQLSEIIERFIFVMPPVEAPPPSLHACHPPPWL 1999
Score = 34.3 bits (77), Expect = 1.4
Identities = 34/114 (29%), Positives = 42/114 (36%), Gaps = 19/114 (16%)
Query: 59 AAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRP----AAPAPAALVAQPGAPGAPADA 114
A +P P P P + LL A +A P AAP A L P P AP
Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASS--ASQALATPLAPMAAPQTAILAPSPAPPLAPL-- 1609
Query: 115 GPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRT 168
PV PG P+ A+ +T P P P ++ A A P P T
Sbjct: 1610 ---PVLAPSPGAAPVLASSQT-PVPVMAPSSTPGTSL-------ASASPVPAPT 1652
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 112 bits (279), Expect = 5e-24
Identities = 127/476 (26%), Positives = 160/476 (33%), Gaps = 69/476 (14%)
Query: 674 QPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP---TGPGQPAPPGQQ 730
+ T+A L S P + PA++ P P P+TP T P +P P +
Sbjct: 180 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIK 238
Query: 731 PPPLAQPTPLPQVLAPQPVVPLQPVP-------PHLPPYLAPASQVGAPAQLKPLQMPQA 783
P P P P P +P P P P AP + PA P
Sbjct: 239 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTT 297
Query: 784 PLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSL 843
P +P P + P P P P PT T P P P PA P
Sbjct: 298 PKEPAPTTPKKPAPTTPKEP----------APTTPKEPTPTTPKEPAPTTKEPAPTTPKE 347
Query: 844 AAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAV 903
AP P PA P P P AP T + P A + +
Sbjct: 348 PAPTAPKKPAPTTPKEPAPTTPKEP-----------APTTTKEPSPTTPKEPAPTTTKSA 396
Query: 904 AQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP--PQPVLP--PQ 959
+P P T PSP T + TP +PA PT P P P P P
Sbjct: 397 PTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA----PTTPKKPAPTTPKEPA 451
Query: 960 PTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATP 1019
PT P +P P T+ P P P + P P P + A P P+ L P PE+ AP TP
Sbjct: 452 PTTPKEPA--PTTTKKPAPTTPKE----PAPTTPKETA-PTTPKKLTPTTPEKLAP-TTP 503
Query: 1020 GSQILLGHPAPYAVDVAAQVPTVPVPPAAVL----SPPLPEVLLPAAP-ELLPQFPSSLA 1074
PAP + A PT P P +P P+ P P E P P A
Sbjct: 504 EK------PAPTTPEELA--PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 555
Query: 1075 --TVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKP 1128
T + P +TA P P + P PT P + + +P
Sbjct: 556 PTTPKEPAPTTPKETAPTTPKGTAPTT----LKEPAPTTPKKPAPKELAPTTTKEP 607
Score = 108 bits (269), Expect = 8e-23
Identities = 155/632 (24%), Positives = 207/632 (32%), Gaps = 116/632 (18%)
Query: 602 TLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPV 661
T+ T T+ + T G+ T S QS+ S D AP+ V + P +
Sbjct: 149 TVETKETTTTNKQTSTDGKEKTT---SAKETQSIEKTSAKDLAPTSK--VLAKPTPKAET 203
Query: 662 LPQSLPSLGAYQQPT-AAPGLPVGSVPAPACPPSLQQHFPDP---------AMSFAPVLP 711
+ P+L ++PT P P + P P +++ P + P P
Sbjct: 204 TTKG-PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 262
Query: 712 PPST---PMPTGPGQPAPPGQQPP--------PLAQPTPLPQV-LAPQPVVPLQPVP--- 756
P+T P PT P +PAP + P P P P P P P +P P
Sbjct: 263 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 322
Query: 757 ----PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVP----PIT--- 805
P P AP ++ AP K P AP +P P + P P P P T
Sbjct: 323 KEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKE--PAPTTPKEPAPTTTKE 379
Query: 806 --PLAGIDGLPPALPDLPTATVPPVP--------------PPQYFSPAVILPSLAAPLPP 849
P + P PT T P P P PA P AP P
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439
Query: 850 ASPALPLQAVKLPHPPGAPLAMPCRTIVPN-----APATIPLLAVAPPGVAALSIHSAVA 904
PA P P P + P AP T A P + +A
Sbjct: 440 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 499
Query: 905 QLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLP 957
+ P ++APT T + T P+ A P P PT P P P P
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 958 --PQPTLP------------PQPVLPPQPTRPPQPVLPPQPMLP-------------PQP 990
P PT P P + P PT P +P P+ + P P P
Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAP 617
Query: 991 VLP--PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQ---VPTVPVP 1045
P P P P P P P P T + L PAP A PT
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT--APTTLKEPAPTTPKKPAPKELAPTTTKG 675
Query: 1046 PAAVLS----PPLPEVLLPAAP-ELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPG 1100
P + S P P+ P P E P P A + ++ P T+ + P P
Sbjct: 676 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP--ETPPPTTSEVSTPTTTKEPT 733
Query: 1101 GPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
+ T +L+ EP + + K PG+P
Sbjct: 734 TIHKSPDESTPELSAEPTPKALENSPKEPGVP 765
Score = 94.7 bits (234), Expect = 9e-19
Identities = 135/582 (23%), Positives = 188/582 (32%), Gaps = 96/582 (16%)
Query: 586 PPEPEEPEADQHLLPPTLPT----SATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLA 641
P P+EP PT P + T + +T +T + ++ +S
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300
Query: 642 DAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQP---TAAPGLPVGSVPAPACPPSLQQH 698
A +P + + P P P+ P+ ++P T P PAP P
Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 359
Query: 699 FPDPAMSFAPVLPPPST---PMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV 755
P P P P+T P PT P +PAP + P P P P P +P
Sbjct: 360 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 419
Query: 756 P-------PHLPPYLAPASQVGAPAQLKPLQ----MPQAPLQPLAQVP-PQMP--PIPVV 801
P P P AP + PA P + P+ P + P P P P P
Sbjct: 420 PTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 478
Query: 802 PPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLA---APLPPASPALPLQA 858
P T L P P+ T P P P +P + P+ P P PA
Sbjct: 479 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPT--TPEELAPTTPEEPTPTTPEEPAPTTPK 536
Query: 859 VKLPHPPGAPLAMPCRTIVPNAPA----TIP--LLAVAPPGVAALSIHSAVAQLPGQPVY 912
P+ P P + P P T P P G A ++ P +P
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP-- 594
Query: 913 PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLP-------- 957
A ++APT T T P+ P P PT P P P P
Sbjct: 595 --APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 652
Query: 958 --PQPTLP-----------------------PQPVLPPQ--PTRPPQPVLPPQPMLPPQP 990
P PT P P P P + PT P +P P
Sbjct: 653 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA----------P 702
Query: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVL 1050
P +PA P PE P E + P T + P +++A+ PT +
Sbjct: 703 TTPKKPA-PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE-PTPKALENSPK 760
Query: 1051 SPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP 1092
P +P PAA + + T +++ P +T T P
Sbjct: 761 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-ETTTAAP 801
Score = 89.0 bits (219), Expect = 5e-17
Identities = 110/471 (23%), Positives = 149/471 (31%), Gaps = 56/471 (11%)
Query: 583 QPGPPEPEEPEADQHLLPPTLPTSATSLA----SDSTFDSGQGSTVYSDSQSSQQSVMLG 638
+P P P+EP PT P A + +T +T + ++ +
Sbjct: 324 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 383
Query: 639 SLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAA--PGLPVGSVPAPACPPSLQ 696
+ + AP+ + + P +S P+ PT P PAP P
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 443
Query: 697 QHFPDPAMSFAPVLPPPST---PMPTGPGQPAPPGQQPPPLAQPTP------LPQVLAPQ 747
P P P P+T P PT P +PAP P A TP P+ LAP
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT--TPKETAPTTPKKLTPTTPEKLAPT 501
Query: 748 ------PVVPLQPVP-------PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ 794
P P + P P P AP + A P P +P P +
Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561
Query: 795 MPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPAL 854
P P P T G P P T P P P+ +P + +P
Sbjct: 562 --PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 855 PLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPA 914
P P P P P PA P G A ++ P +P
Sbjct: 620 PKGTA--PTTPKEP-----APTTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKP---- 663
Query: 915 AFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLPPQPTLPPQPV 967
A ++APT T T P+ P P PT P P P P P V
Sbjct: 664 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 723
Query: 968 LPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT 1018
P T+ P + P+ P P + P +P +P PAAT
Sbjct: 724 STPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTKTPAAT 773
Score = 72.0 bits (175), Expect = 6e-12
Identities = 81/389 (20%), Positives = 122/389 (31%), Gaps = 43/389 (11%)
Query: 583 QPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLAD 642
+P P P+EP P PT+ A + + +T + ++
Sbjct: 425 EPAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482
Query: 643 AAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702
A +P + + P P P+ + P P + P P + + P+
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 542
Query: 703 AMSFAPVLPPPSTPMPTGPGQPAP--PGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLP 760
AP P P PT P +PAP P + P + T + P P P +P P L
Sbjct: 543 PKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 600
Query: 761 PYLA---PASQVGAPAQLKPL-QMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPA 816
P ++ PA P P P +P P + P P P G P
Sbjct: 601 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTP--------KGTAPT 650
Query: 817 LPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTI 876
P T P P P+ +P + +P P + P P P +
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKEPAPTTPKKP 708
Query: 877 VPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMR 936
P P T PP + +S + + PT + SP + +
Sbjct: 709 APTTPET------PPPTTSEVSTPTTTKE---------------PTTIHKSPDESTPELS 747
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPPQ 965
A P AL P P P P+
Sbjct: 748 AEPTPKALENSPKEPGVPTTKTPAATKPE 776
Score = 67.8 bits (164), Expect = 1e-10
Identities = 120/567 (21%), Positives = 184/567 (32%), Gaps = 100/567 (17%)
Query: 568 PVPLQVQVTYHAQAGQPGPPEPEE----------PEADQHLLPPT----LPTSATSLASD 613
P P + +P P P+E P + L P T PT+ LA
Sbjct: 458 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP- 516
Query: 614 STFDSGQGSTVYSDSQSSQQSVMLGSLADAAPS-PAQCVCSPPVSEGPVLP-QSLPSLGA 671
+T + +T + ++ ++ + + AP+ P + + P P P ++ P+
Sbjct: 517 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 576
Query: 672 YQQPTA----APGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPP---PSTPMPTGPGQP 724
PT AP P P P + ++ AP P P+TP P P
Sbjct: 577 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 636
Query: 725 APPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA--PASQVG-APAQLKPLQM- 780
P P PT L + P P P +P P L P P S PA P +
Sbjct: 637 KEPAPTTPKGTAPTTLKE---PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 693
Query: 781 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
P P +P P + P P P TP PP ++ T T P + SP
Sbjct: 694 PTTPKEPAPTTPKK--PAPTTPE-TP-------PPTTSEVSTPTTTKEPTTIHKSPDEST 743
Query: 841 PSLAA-PLP------PASPALPLQAVKLPHPPGAPLAMPCRTI------VPNAPATIPLL 887
P L+A P P P P +P P +T P P +
Sbjct: 744 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803
Query: 888 AVAPPGVAALSIHSAVAQLPGQ-----------------------PVYPAAFPQMAPTDV 924
+ S + Q P + T++
Sbjct: 804 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 863
Query: 925 PPSPHHTVQ------NMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQP 978
P T + N +AT P+P P + P +PT +P P+ R P+
Sbjct: 864 MNKPEETAKPKDRATNSKATTPKPQKPTK--------APKKPTSTKKPKTMPR-VRKPKT 914
Query: 979 VLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP-APYAVDVAA 1037
P+ M P L P + + L P TP S+++ +P + A
Sbjct: 915 TPTPRKMTSTMPELNPTSRI------AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEG 968
Query: 1038 QVPTVPVPPAAVLSPPLPEV-LLPAAP 1063
+ P + + P + P++ LP P
Sbjct: 969 ETPHMLLRPHVFMPEVTPDMDYLPRVP 995
Score = 67.4 bits (163), Expect = 1e-10
Identities = 129/644 (20%), Positives = 207/644 (32%), Gaps = 62/644 (9%)
Query: 1275 TSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLP 1334
T+ ST G ++++Q+ +++ T K P AE ++P P
Sbjct: 157 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP 216
Query: 1335 LSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP-------PAPLAPS 1387
+ P E + + + K P+ + P P PAP P
Sbjct: 217 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 276
Query: 1388 SPPVTALPQDGAAPATS----TMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAP 1443
P T + AP T+ T P+ + T + P TP+ E + P T P
Sbjct: 277 EPAPTTTKEP--APTTTKSAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPTPTTP 330
Query: 1444 LAVQPLVVGLAPCTP---APEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1500
P AP TP AP A + P+EP P EP+P + T +P+ P
Sbjct: 331 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP-TTTKEPSPTTPKEPA 389
Query: 1501 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1560
P + T + P+P + P P + + P P + +K
Sbjct: 390 PTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKKPAPTT 446
Query: 1561 YQEHVPTS-SASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLP 1619
+E PT+ A T + EP + P P++ + P
Sbjct: 447 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 506
Query: 1620 QPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPA 1679
P + ELAPT T+ A ++P++ + P+ P++ PA
Sbjct: 507 APTTPE-ELAPTT-PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PA 563
Query: 1680 FVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVS 1739
P PT G A + EP P+ + P T K P
Sbjct: 564 PTTPKETAPT-TPKGTAPTTLKEPAPTTPKKPAPKELAPTT---------TKEPTSTTCD 613
Query: 1740 SPAKTVGRFSVVSTQDEWTLASPHSLRYSAP----PDVYLDEAPSSPDVKLAVRRAQTAS 1795
PA T + + +T E +P + P P + AP++P A T +
Sbjct: 614 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 673
Query: 1796 SIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGP 1855
G S P+ P + P + P + P
Sbjct: 674 K---GPTSTTSDKPAPTTPKETAPTTPKEPAPTT-----------------PKKPAPTTP 713
Query: 1856 ETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQS 1899
ETP +V T + T + ++ EL K L++
Sbjct: 714 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 757
Score = 38.1 bits (87), Expect = 0.097
Identities = 34/149 (22%), Positives = 53/149 (35%), Gaps = 8/149 (5%)
Query: 29 PRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAER 88
P+A+ GP + + +EP A+ P P ++ + +
Sbjct: 199 PKAETTTKGPALTTPKEPTPTTPKEP----ASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 89 ARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
A P PAP + AP P + P P T+EP P +A T P ++ A
Sbjct: 255 APTTPKEPAPTT--TKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310
Query: 149 ATVRKEDEGAAEAKPEPGRTRRDEPEEEE 177
T KE +P P + P +E
Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKE 339
Score = 37.7 bits (86), Expect = 0.13
Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 3/81 (3%)
Query: 96 PAPAALVAQPGAPGAPADAGPE---PVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVR 152
PAP + P P PA P+ P +EP P T P +E A T
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345
Query: 153 KEDEGAAEAKPEPGRTRRDEP 173
KE A KP P + P
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAP 366
Score = 35.4 bits (80), Expect = 0.63
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 3/90 (3%)
Query: 87 ERARGRPAAPAPAALVA-QPGAPGAPADAGPE--PVGTQEPGPDPIAAAVETAPAPDGGP 143
E A P PAP P P PA + P T+EP P +A T P
Sbjct: 363 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422
Query: 144 REEAAATVRKEDEGAAEAKPEPGRTRRDEP 173
+E A T KE KP P + P
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452
Score = 34.7 bits (78), Expect = 1.1
Identities = 43/176 (24%), Positives = 53/176 (30%), Gaps = 18/176 (10%)
Query: 7 RRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPG-- 64
+ P T EP P EP A P +S + +E P AP
Sbjct: 260 KEPAPTTTKEPA----PTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 65 --PQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQ 122
P P P + + E A P PAP A P P P P +
Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPTTPKEPAPTTPK 370
Query: 123 EPGPDPIAAAVETAPAPDGGPREEAAATVRKE-----DEGAAEAKPEPGRTRRDEP 173
EP P T P ++A T KE + A EP T EP
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 426
Score = 34.3 bits (77), Expect = 1.4
Identities = 32/132 (24%), Positives = 45/132 (34%), Gaps = 4/132 (3%)
Query: 44 RSVVESDQEEPPGLEAAEAPG-PQPPQPLQRRVLLLCKTRRLIAERARGRPAAPA-PAAL 101
+S + +E P AP P+ P P + T+ P P PA
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312
Query: 102 VAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEA 161
+ AP P + P P +EP P A T P ++ A T KE
Sbjct: 313 TPKEPAPTTPKE--PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 370
Query: 162 KPEPGRTRRDEP 173
+P P T+ P
Sbjct: 371 EPAPTTTKEPSP 382
Score = 33.5 bits (75), Expect = 2.4
Identities = 38/174 (21%), Positives = 55/174 (31%), Gaps = 28/174 (16%)
Query: 19 RGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLL 78
+G P + EP A P++ + + + +EP + P P P+
Sbjct: 576 KGTAPTTLKEP----APTTPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGT------- 623
Query: 79 CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGP----EPVGTQEPGPDPIAAAVE 134
A P PAP + AP P P EP T P P A
Sbjct: 624 ----------APTTPKEPAPTT--PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 671
Query: 135 TAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVAT 188
T P ++ A T KE +P P ++ P E V+T
Sbjct: 672 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 112 bits (279), Expect = 5e-24
Identities = 127/476 (26%), Positives = 160/476 (33%), Gaps = 69/476 (14%)
Query: 674 QPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP---TGPGQPAPPGQQ 730
+ T+A L S P + PA++ P P P+TP T P +P P +
Sbjct: 221 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIK 279
Query: 731 PPPLAQPTPLPQVLAPQPVVPLQPVP-------PHLPPYLAPASQVGAPAQLKPLQMPQA 783
P P P P P +P P P P AP + PA P
Sbjct: 280 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTT 338
Query: 784 PLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSL 843
P +P P + P P P P PT T P P P PA P
Sbjct: 339 PKEPAPTTPKKPAPTTPKEP----------APTTPKEPTPTTPKEPAPTTKEPAPTTPKE 388
Query: 844 AAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAV 903
AP P PA P P P AP T + P A + +
Sbjct: 389 PAPTAPKKPAPTTPKEPAPTTPKEP-----------APTTTKEPSPTTPKEPAPTTTKSA 437
Query: 904 AQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP--PQPVLP--PQ 959
+P P T PSP T + TP +PA PT P P P P P
Sbjct: 438 PTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA----PTTPKKPAPTTPKEPA 492
Query: 960 PTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATP 1019
PT P +P P T+ P P P + P P P + A P P+ L P PE+ AP TP
Sbjct: 493 PTTPKEPA--PTTTKKPAPTTPKE----PAPTTPKETA-PTTPKKLTPTTPEKLAP-TTP 544
Query: 1020 GSQILLGHPAPYAVDVAAQVPTVPVPPAAVL----SPPLPEVLLPAAP-ELLPQFPSSLA 1074
PAP + A PT P P +P P+ P P E P P A
Sbjct: 545 EK------PAPTTPEELA--PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 596
Query: 1075 --TVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKP 1128
T + P +TA P P + P PT P + + +P
Sbjct: 597 PTTPKEPAPTTPKETAPTTPKGTAPTT----LKEPAPTTPKKPAPKELAPTTTKEP 648
Score = 108 bits (269), Expect = 8e-23
Identities = 155/632 (24%), Positives = 207/632 (32%), Gaps = 116/632 (18%)
Query: 602 TLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPV 661
T+ T T+ + T G+ T S QS+ S D AP+ V + P +
Sbjct: 190 TVETKETTTTNKQTSTDGKEKTT---SAKETQSIEKTSAKDLAPTSK--VLAKPTPKAET 244
Query: 662 LPQSLPSLGAYQQPT-AAPGLPVGSVPAPACPPSLQQHFPDP---------AMSFAPVLP 711
+ P+L ++PT P P + P P +++ P + P P
Sbjct: 245 TTKG-PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 303
Query: 712 PPST---PMPTGPGQPAPPGQQPP--------PLAQPTPLPQV-LAPQPVVPLQPVP--- 756
P+T P PT P +PAP + P P P P P P P +P P
Sbjct: 304 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 363
Query: 757 ----PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVP----PIT--- 805
P P AP ++ AP K P AP +P P + P P P P T
Sbjct: 364 KEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKE--PAPTTPKEPAPTTTKE 420
Query: 806 --PLAGIDGLPPALPDLPTATVPPVP--------------PPQYFSPAVILPSLAAPLPP 849
P + P PT T P P P PA P AP P
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480
Query: 850 ASPALPLQAVKLPHPPGAPLAMPCRTIVPN-----APATIPLLAVAPPGVAALSIHSAVA 904
PA P P P + P AP T A P + +A
Sbjct: 481 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 540
Query: 905 QLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLP 957
+ P ++APT T + T P+ A P P PT P P P P
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 958 --PQPTLP------------PQPVLPPQPTRPPQPVLPPQPMLP-------------PQP 990
P PT P P + P PT P +P P+ + P P P
Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAP 658
Query: 991 VLP--PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQ---VPTVPVP 1045
P P P P P P P P T + L PAP A PT
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT--APTTLKEPAPTTPKKPAPKELAPTTTKG 716
Query: 1046 PAAVLS----PPLPEVLLPAAP-ELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPG 1100
P + S P P+ P P E P P A + ++ P T+ + P P
Sbjct: 717 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP--ETPPPTTSEVSTPTTTKEPT 774
Query: 1101 GPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
+ T +L+ EP + + K PG+P
Sbjct: 775 TIHKSPDESTPELSAEPTPKALENSPKEPGVP 806
Score = 94.7 bits (234), Expect = 9e-19
Identities = 135/582 (23%), Positives = 188/582 (32%), Gaps = 96/582 (16%)
Query: 586 PPEPEEPEADQHLLPPTLPT----SATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLA 641
P P+EP PT P + T + +T +T + ++ +S
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341
Query: 642 DAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQP---TAAPGLPVGSVPAPACPPSLQQH 698
A +P + + P P P+ P+ ++P T P PAP P
Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 400
Query: 699 FPDPAMSFAPVLPPPST---PMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV 755
P P P P+T P PT P +PAP + P P P P P +P
Sbjct: 401 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 460
Query: 756 P-------PHLPPYLAPASQVGAPAQLKPLQ----MPQAPLQPLAQVP-PQMP--PIPVV 801
P P P AP + PA P + P+ P + P P P P P
Sbjct: 461 PTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 519
Query: 802 PPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLA---APLPPASPALPLQA 858
P T L P P+ T P P P +P + P+ P P PA
Sbjct: 520 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPT--TPEELAPTTPEEPTPTTPEEPAPTTPK 577
Query: 859 VKLPHPPGAPLAMPCRTIVPNAPA----TIP--LLAVAPPGVAALSIHSAVAQLPGQPVY 912
P+ P P + P P T P P G A ++ P +P
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP-- 635
Query: 913 PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLP-------- 957
A ++APT T T P+ P P PT P P P P
Sbjct: 636 --APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 693
Query: 958 --PQPTLP-----------------------PQPVLPPQ--PTRPPQPVLPPQPMLPPQP 990
P PT P P P P + PT P +P P
Sbjct: 694 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA----------P 743
Query: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVL 1050
P +PA P PE P E + P T + P +++A+ PT +
Sbjct: 744 TTPKKPA-PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE-PTPKALENSPK 801
Query: 1051 SPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP 1092
P +P PAA + + T +++ P +T T P
Sbjct: 802 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-ETTTAAP 842
Score = 89.0 bits (219), Expect = 5e-17
Identities = 110/471 (23%), Positives = 149/471 (31%), Gaps = 56/471 (11%)
Query: 583 QPGPPEPEEPEADQHLLPPTLPTSATSLA----SDSTFDSGQGSTVYSDSQSSQQSVMLG 638
+P P P+EP PT P A + +T +T + ++ +
Sbjct: 365 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 424
Query: 639 SLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAA--PGLPVGSVPAPACPPSLQ 696
+ + AP+ + + P +S P+ PT P PAP P
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 484
Query: 697 QHFPDPAMSFAPVLPPPST---PMPTGPGQPAPPGQQPPPLAQPTP------LPQVLAPQ 747
P P P P+T P PT P +PAP P A TP P+ LAP
Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT--TPKETAPTTPKKLTPTTPEKLAPT 542
Query: 748 ------PVVPLQPVP-------PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ 794
P P + P P P AP + A P P +P P +
Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602
Query: 795 MPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPAL 854
P P P T G P P T P P P+ +P + +P
Sbjct: 603 --PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660
Query: 855 PLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPA 914
P P P P P PA P G A ++ P +P
Sbjct: 661 PKGTA--PTTPKEP-----APTTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKP---- 704
Query: 915 AFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLPPQPTLPPQPV 967
A ++APT T T P+ P P PT P P P P P V
Sbjct: 705 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 764
Query: 968 LPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT 1018
P T+ P + P+ P P + P +P +P PAAT
Sbjct: 765 STPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTKTPAAT 814
Score = 72.0 bits (175), Expect = 6e-12
Identities = 81/389 (20%), Positives = 122/389 (31%), Gaps = 43/389 (11%)
Query: 583 QPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLAD 642
+P P P+EP P PT+ A + + +T + ++
Sbjct: 466 EPAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523
Query: 643 AAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702
A +P + + P P P+ + P P + P P + + P+
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 583
Query: 703 AMSFAPVLPPPSTPMPTGPGQPAP--PGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLP 760
AP P P PT P +PAP P + P + T + P P P +P P L
Sbjct: 584 PKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 641
Query: 761 PYLA---PASQVGAPAQLKPL-QMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPA 816
P ++ PA P P P +P P + P P P G P
Sbjct: 642 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTP--------KGTAPT 691
Query: 817 LPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTI 876
P T P P P+ +P + +P P + P P P +
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKEPAPTTPKKP 749
Query: 877 VPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMR 936
P P T PP + +S + + PT + SP + +
Sbjct: 750 APTTPET------PPPTTSEVSTPTTTKE---------------PTTIHKSPDESTPELS 788
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPPQ 965
A P AL P P P P+
Sbjct: 789 AEPTPKALENSPKEPGVPTTKTPAATKPE 817
Score = 67.8 bits (164), Expect = 1e-10
Identities = 120/567 (21%), Positives = 184/567 (32%), Gaps = 100/567 (17%)
Query: 568 PVPLQVQVTYHAQAGQPGPPEPEE----------PEADQHLLPPT----LPTSATSLASD 613
P P + +P P P+E P + L P T PT+ LA
Sbjct: 499 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP- 557
Query: 614 STFDSGQGSTVYSDSQSSQQSVMLGSLADAAPS-PAQCVCSPPVSEGPVLP-QSLPSLGA 671
+T + +T + ++ ++ + + AP+ P + + P P P ++ P+
Sbjct: 558 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 617
Query: 672 YQQPTA----APGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPP---PSTPMPTGPGQP 724
PT AP P P P + ++ AP P P+TP P P
Sbjct: 618 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 677
Query: 725 APPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA--PASQVG-APAQLKPLQM- 780
P P PT L + P P P +P P L P P S PA P +
Sbjct: 678 KEPAPTTPKGTAPTTLKE---PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 734
Query: 781 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
P P +P P + P P P TP PP ++ T T P + SP
Sbjct: 735 PTTPKEPAPTTPKK--PAPTTPE-TP-------PPTTSEVSTPTTTKEPTTIHKSPDEST 784
Query: 841 PSLAA-PLP------PASPALPLQAVKLPHPPGAPLAMPCRTI------VPNAPATIPLL 887
P L+A P P P P +P P +T P P +
Sbjct: 785 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844
Query: 888 AVAPPGVAALSIHSAVAQLPGQ-----------------------PVYPAAFPQMAPTDV 924
+ S + Q P + T++
Sbjct: 845 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 904
Query: 925 PPSPHHTVQ------NMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQP 978
P T + N +AT P+P P + P +PT +P P+ R P+
Sbjct: 905 MNKPEETAKPKDRATNSKATTPKPQKPTK--------APKKPTSTKKPKTMPR-VRKPKT 955
Query: 979 VLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP-APYAVDVAA 1037
P+ M P L P + + L P TP S+++ +P + A
Sbjct: 956 TPTPRKMTSTMPELNPTSRI------AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEG 1009
Query: 1038 QVPTVPVPPAAVLSPPLPEV-LLPAAP 1063
+ P + + P + P++ LP P
Sbjct: 1010 ETPHMLLRPHVFMPEVTPDMDYLPRVP 1036
Score = 67.4 bits (163), Expect = 1e-10
Identities = 129/644 (20%), Positives = 207/644 (32%), Gaps = 62/644 (9%)
Query: 1275 TSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLP 1334
T+ ST G ++++Q+ +++ T K P AE ++P P
Sbjct: 198 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP 257
Query: 1335 LSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP-------PAPLAPS 1387
+ P E + + + K P+ + P P PAP P
Sbjct: 258 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 317
Query: 1388 SPPVTALPQDGAAPATS----TMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAP 1443
P T + AP T+ T P+ + T + P TP+ E + P T P
Sbjct: 318 EPAPTTTKEP--APTTTKSAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPTPTTP 371
Query: 1444 LAVQPLVVGLAPCTP---APEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1500
P AP TP AP A + P+EP P EP+P + T +P+ P
Sbjct: 372 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP-TTTKEPSPTTPKEPA 430
Query: 1501 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1560
P + T + P+P + P P + + P P + +K
Sbjct: 431 PTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKKPAPTT 487
Query: 1561 YQEHVPTS-SASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLP 1619
+E PT+ A T + EP + P P++ + P
Sbjct: 488 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 547
Query: 1620 QPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPA 1679
P + ELAPT T+ A ++P++ + P+ P++ PA
Sbjct: 548 APTTPE-ELAPTT-PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PA 604
Query: 1680 FVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVS 1739
P PT G A + EP P+ + P T K P
Sbjct: 605 PTTPKETAPT-TPKGTAPTTLKEPAPTTPKKPAPKELAPTT---------TKEPTSTTCD 654
Query: 1740 SPAKTVGRFSVVSTQDEWTLASPHSLRYSAP----PDVYLDEAPSSPDVKLAVRRAQTAS 1795
PA T + + +T E +P + P P + AP++P A T +
Sbjct: 655 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 714
Query: 1796 SIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGP 1855
G S P+ P + P + P + P
Sbjct: 715 K---GPTSTTSDKPAPTTPKETAPTTPKEPAPTT-----------------PKKPAPTTP 754
Query: 1856 ETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQS 1899
ETP +V T + T + ++ EL K L++
Sbjct: 755 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 798
Score = 38.1 bits (87), Expect = 0.097
Identities = 34/149 (22%), Positives = 53/149 (35%), Gaps = 8/149 (5%)
Query: 29 PRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAER 88
P+A+ GP + + +EP A+ P P ++ + +
Sbjct: 240 PKAETTTKGPALTTPKEPTPTTPKEP----ASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 89 ARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
A P PAP + AP P + P P T+EP P +A T P ++ A
Sbjct: 296 APTTPKEPAPTT--TKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351
Query: 149 ATVRKEDEGAAEAKPEPGRTRRDEPEEEE 177
T KE +P P + P +E
Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKE 380
Score = 37.7 bits (86), Expect = 0.13
Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 3/81 (3%)
Query: 96 PAPAALVAQPGAPGAPADAGPE---PVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVR 152
PAP + P P PA P+ P +EP P T P +E A T
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386
Query: 153 KEDEGAAEAKPEPGRTRRDEP 173
KE A KP P + P
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAP 407
Score = 35.4 bits (80), Expect = 0.63
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 3/90 (3%)
Query: 87 ERARGRPAAPAPAALVA-QPGAPGAPADAGPE--PVGTQEPGPDPIAAAVETAPAPDGGP 143
E A P PAP P P PA + P T+EP P +A T P
Sbjct: 404 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463
Query: 144 REEAAATVRKEDEGAAEAKPEPGRTRRDEP 173
+E A T KE KP P + P
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493
Score = 34.7 bits (78), Expect = 1.1
Identities = 43/176 (24%), Positives = 53/176 (30%), Gaps = 18/176 (10%)
Query: 7 RRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPG-- 64
+ P T EP P EP A P +S + +E P AP
Sbjct: 301 KEPAPTTTKEPA----PTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 65 --PQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQ 122
P P P + + E A P PAP A P P P P +
Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPTTPKEPAPTTPK 411
Query: 123 EPGPDPIAAAVETAPAPDGGPREEAAATVRKE-----DEGAAEAKPEPGRTRRDEP 173
EP P T P ++A T KE + A EP T EP
Sbjct: 412 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 467
Score = 34.3 bits (77), Expect = 1.4
Identities = 32/132 (24%), Positives = 45/132 (34%), Gaps = 4/132 (3%)
Query: 44 RSVVESDQEEPPGLEAAEAPG-PQPPQPLQRRVLLLCKTRRLIAERARGRPAAPA-PAAL 101
+S + +E P AP P+ P P + T+ P P PA
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353
Query: 102 VAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEA 161
+ AP P + P P +EP P A T P ++ A T KE
Sbjct: 354 TPKEPAPTTPKE--PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 411
Query: 162 KPEPGRTRRDEP 173
+P P T+ P
Sbjct: 412 EPAPTTTKEPSP 423
Score = 33.5 bits (75), Expect = 2.4
Identities = 38/174 (21%), Positives = 55/174 (31%), Gaps = 28/174 (16%)
Query: 19 RGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLL 78
+G P + EP A P++ + + + +EP + P P P+
Sbjct: 617 KGTAPTTLKEP----APTTPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGT------- 664
Query: 79 CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGP----EPVGTQEPGPDPIAAAVE 134
A P PAP + AP P P EP T P P A
Sbjct: 665 ----------APTTPKEPAPTT--PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 712
Query: 135 TAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVAT 188
T P ++ A T KE +P P ++ P E V+T
Sbjct: 713 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 112 bits (279), Expect = 5e-24
Identities = 127/476 (26%), Positives = 160/476 (33%), Gaps = 69/476 (14%)
Query: 674 QPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP---TGPGQPAPPGQQ 730
+ T+A L S P + PA++ P P P+TP T P +P P +
Sbjct: 273 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIK 331
Query: 731 PPPLAQPTPLPQVLAPQPVVPLQPVP-------PHLPPYLAPASQVGAPAQLKPLQMPQA 783
P P P P P +P P P P AP + PA P
Sbjct: 332 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTT 390
Query: 784 PLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSL 843
P +P P + P P P P PT T P P P PA P
Sbjct: 391 PKEPAPTTPKKPAPTTPKEP----------APTTPKEPTPTTPKEPAPTTKEPAPTTPKE 440
Query: 844 AAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAV 903
AP P PA P P P AP T + P A + +
Sbjct: 441 PAPTAPKKPAPTTPKEPAPTTPKEP-----------APTTTKEPSPTTPKEPAPTTTKSA 489
Query: 904 AQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP--PQPVLP--PQ 959
+P P T PSP T + TP +PA PT P P P P P
Sbjct: 490 PTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA----PTTPKKPAPTTPKEPA 544
Query: 960 PTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATP 1019
PT P +P P T+ P P P + P P P + A P P+ L P PE+ AP TP
Sbjct: 545 PTTPKEPA--PTTTKKPAPTTPKE----PAPTTPKETA-PTTPKKLTPTTPEKLAP-TTP 596
Query: 1020 GSQILLGHPAPYAVDVAAQVPTVPVPPAAVL----SPPLPEVLLPAAP-ELLPQFPSSLA 1074
PAP + A PT P P +P P+ P P E P P A
Sbjct: 597 EK------PAPTTPEELA--PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 648
Query: 1075 --TVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKP 1128
T + P +TA P P + P PT P + + +P
Sbjct: 649 PTTPKEPAPTTPKETAPTTPKGTAPTT----LKEPAPTTPKKPAPKELAPTTTKEP 700
Score = 108 bits (269), Expect = 8e-23
Identities = 155/632 (24%), Positives = 207/632 (32%), Gaps = 116/632 (18%)
Query: 602 TLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPV 661
T+ T T+ + T G+ T S QS+ S D AP+ V + P +
Sbjct: 242 TVETKETTTTNKQTSTDGKEKTT---SAKETQSIEKTSAKDLAPTSK--VLAKPTPKAET 296
Query: 662 LPQSLPSLGAYQQPT-AAPGLPVGSVPAPACPPSLQQHFPDP---------AMSFAPVLP 711
+ P+L ++PT P P + P P +++ P + P P
Sbjct: 297 TTKG-PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 355
Query: 712 PPST---PMPTGPGQPAPPGQQPP--------PLAQPTPLPQV-LAPQPVVPLQPVP--- 756
P+T P PT P +PAP + P P P P P P P +P P
Sbjct: 356 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 415
Query: 757 ----PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVP----PIT--- 805
P P AP ++ AP K P AP +P P + P P P P T
Sbjct: 416 KEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKE--PAPTTPKEPAPTTTKE 472
Query: 806 --PLAGIDGLPPALPDLPTATVPPVP--------------PPQYFSPAVILPSLAAPLPP 849
P + P PT T P P P PA P AP P
Sbjct: 473 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 532
Query: 850 ASPALPLQAVKLPHPPGAPLAMPCRTIVPN-----APATIPLLAVAPPGVAALSIHSAVA 904
PA P P P + P AP T A P + +A
Sbjct: 533 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 592
Query: 905 QLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLP 957
+ P ++APT T + T P+ A P P PT P P P P
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 652
Query: 958 --PQPTLP------------PQPVLPPQPTRPPQPVLPPQPMLP-------------PQP 990
P PT P P + P PT P +P P+ + P P P
Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAP 710
Query: 991 VLP--PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQ---VPTVPVP 1045
P P P P P P P P T + L PAP A PT
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT--APTTLKEPAPTTPKKPAPKELAPTTTKG 768
Query: 1046 PAAVLS----PPLPEVLLPAAP-ELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPG 1100
P + S P P+ P P E P P A + ++ P T+ + P P
Sbjct: 769 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP--ETPPPTTSEVSTPTTTKEPT 826
Query: 1101 GPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
+ T +L+ EP + + K PG+P
Sbjct: 827 TIHKSPDESTPELSAEPTPKALENSPKEPGVP 858
Score = 94.7 bits (234), Expect = 9e-19
Identities = 135/582 (23%), Positives = 188/582 (32%), Gaps = 96/582 (16%)
Query: 586 PPEPEEPEADQHLLPPTLPT----SATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLA 641
P P+EP PT P + T + +T +T + ++ +S
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393
Query: 642 DAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQP---TAAPGLPVGSVPAPACPPSLQQH 698
A +P + + P P P+ P+ ++P T P PAP P
Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 452
Query: 699 FPDPAMSFAPVLPPPST---PMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV 755
P P P P+T P PT P +PAP + P P P P P +P
Sbjct: 453 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 512
Query: 756 P-------PHLPPYLAPASQVGAPAQLKPLQ----MPQAPLQPLAQVP-PQMP--PIPVV 801
P P P AP + PA P + P+ P + P P P P P
Sbjct: 513 PTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 571
Query: 802 PPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLA---APLPPASPALPLQA 858
P T L P P+ T P P P +P + P+ P P PA
Sbjct: 572 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPT--TPEELAPTTPEEPTPTTPEEPAPTTPK 629
Query: 859 VKLPHPPGAPLAMPCRTIVPNAPA----TIP--LLAVAPPGVAALSIHSAVAQLPGQPVY 912
P+ P P + P P T P P G A ++ P +P
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP-- 687
Query: 913 PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLP-------- 957
A ++APT T T P+ P P PT P P P P
Sbjct: 688 --APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 745
Query: 958 --PQPTLP-----------------------PQPVLPPQ--PTRPPQPVLPPQPMLPPQP 990
P PT P P P P + PT P +P P
Sbjct: 746 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA----------P 795
Query: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVL 1050
P +PA P PE P E + P T + P +++A+ PT +
Sbjct: 796 TTPKKPA-PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE-PTPKALENSPK 853
Query: 1051 SPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP 1092
P +P PAA + + T +++ P +T T P
Sbjct: 854 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-ETTTAAP 894
Score = 89.0 bits (219), Expect = 5e-17
Identities = 110/471 (23%), Positives = 149/471 (31%), Gaps = 56/471 (11%)
Query: 583 QPGPPEPEEPEADQHLLPPTLPTSATSLA----SDSTFDSGQGSTVYSDSQSSQQSVMLG 638
+P P P+EP PT P A + +T +T + ++ +
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 476
Query: 639 SLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAA--PGLPVGSVPAPACPPSLQ 696
+ + AP+ + + P +S P+ PT P PAP P
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 536
Query: 697 QHFPDPAMSFAPVLPPPST---PMPTGPGQPAPPGQQPPPLAQPTP------LPQVLAPQ 747
P P P P+T P PT P +PAP P A TP P+ LAP
Sbjct: 537 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT--TPKETAPTTPKKLTPTTPEKLAPT 594
Query: 748 ------PVVPLQPVP-------PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ 794
P P + P P P AP + A P P +P P +
Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654
Query: 795 MPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPAL 854
P P P T G P P T P P P+ +P + +P
Sbjct: 655 --PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 712
Query: 855 PLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPA 914
P P P P P PA P G A ++ P +P
Sbjct: 713 PKGTA--PTTPKEP-----APTTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKP---- 756
Query: 915 AFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLPPQPTLPPQPV 967
A ++APT T T P+ P P PT P P P P P V
Sbjct: 757 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 816
Query: 968 LPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT 1018
P T+ P + P+ P P + P +P +P PAAT
Sbjct: 817 STPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTKTPAAT 866
Score = 72.0 bits (175), Expect = 6e-12
Identities = 81/389 (20%), Positives = 122/389 (31%), Gaps = 43/389 (11%)
Query: 583 QPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLAD 642
+P P P+EP P PT+ A + + +T + ++
Sbjct: 518 EPAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 575
Query: 643 AAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702
A +P + + P P P+ + P P + P P + + P+
Sbjct: 576 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 635
Query: 703 AMSFAPVLPPPSTPMPTGPGQPAP--PGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLP 760
AP P P PT P +PAP P + P + T + P P P +P P L
Sbjct: 636 PKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 693
Query: 761 PYLA---PASQVGAPAQLKPL-QMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPA 816
P ++ PA P P P +P P + P P P G P
Sbjct: 694 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTP--------KGTAPT 743
Query: 817 LPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTI 876
P T P P P+ +P + +P P + P P P +
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKEPAPTTPKKP 801
Query: 877 VPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMR 936
P P T PP + +S + + PT + SP + +
Sbjct: 802 APTTPET------PPPTTSEVSTPTTTKE---------------PTTIHKSPDESTPELS 840
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPPQ 965
A P AL P P P P+
Sbjct: 841 AEPTPKALENSPKEPGVPTTKTPAATKPE 869
Score = 67.8 bits (164), Expect = 1e-10
Identities = 120/567 (21%), Positives = 184/567 (32%), Gaps = 100/567 (17%)
Query: 568 PVPLQVQVTYHAQAGQPGPPEPEE----------PEADQHLLPPT----LPTSATSLASD 613
P P + +P P P+E P + L P T PT+ LA
Sbjct: 551 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP- 609
Query: 614 STFDSGQGSTVYSDSQSSQQSVMLGSLADAAPS-PAQCVCSPPVSEGPVLP-QSLPSLGA 671
+T + +T + ++ ++ + + AP+ P + + P P P ++ P+
Sbjct: 610 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 669
Query: 672 YQQPTA----APGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPP---PSTPMPTGPGQP 724
PT AP P P P + ++ AP P P+TP P P
Sbjct: 670 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 729
Query: 725 APPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA--PASQVG-APAQLKPLQM- 780
P P PT L + P P P +P P L P P S PA P +
Sbjct: 730 KEPAPTTPKGTAPTTLKE---PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 786
Query: 781 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
P P +P P + P P P TP PP ++ T T P + SP
Sbjct: 787 PTTPKEPAPTTPKK--PAPTTPE-TP-------PPTTSEVSTPTTTKEPTTIHKSPDEST 836
Query: 841 PSLAA-PLP------PASPALPLQAVKLPHPPGAPLAMPCRTI------VPNAPATIPLL 887
P L+A P P P P +P P +T P P +
Sbjct: 837 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 896
Query: 888 AVAPPGVAALSIHSAVAQLPGQ-----------------------PVYPAAFPQMAPTDV 924
+ S + Q P + T++
Sbjct: 897 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 956
Query: 925 PPSPHHTVQ------NMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQP 978
P T + N +AT P+P P + P +PT +P P+ R P+
Sbjct: 957 MNKPEETAKPKDRATNSKATTPKPQKPTK--------APKKPTSTKKPKTMPR-VRKPKT 1007
Query: 979 VLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP-APYAVDVAA 1037
P+ M P L P + + L P TP S+++ +P + A
Sbjct: 1008 TPTPRKMTSTMPELNPTSRI------AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEG 1061
Query: 1038 QVPTVPVPPAAVLSPPLPEV-LLPAAP 1063
+ P + + P + P++ LP P
Sbjct: 1062 ETPHMLLRPHVFMPEVTPDMDYLPRVP 1088
Score = 67.4 bits (163), Expect = 1e-10
Identities = 129/644 (20%), Positives = 207/644 (32%), Gaps = 62/644 (9%)
Query: 1275 TSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLP 1334
T+ ST G ++++Q+ +++ T K P AE ++P P
Sbjct: 250 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP 309
Query: 1335 LSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP-------PAPLAPS 1387
+ P E + + + K P+ + P P PAP P
Sbjct: 310 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 369
Query: 1388 SPPVTALPQDGAAPATS----TMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAP 1443
P T + AP T+ T P+ + T + P TP+ E + P T P
Sbjct: 370 EPAPTTTKEP--APTTTKSAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPTPTTP 423
Query: 1444 LAVQPLVVGLAPCTP---APEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1500
P AP TP AP A + P+EP P EP+P + T +P+ P
Sbjct: 424 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP-TTTKEPSPTTPKEPA 482
Query: 1501 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1560
P + T + P+P + P P + + P P + +K
Sbjct: 483 PTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKKPAPTT 539
Query: 1561 YQEHVPTS-SASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLP 1619
+E PT+ A T + EP + P P++ + P
Sbjct: 540 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 599
Query: 1620 QPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPA 1679
P + ELAPT T+ A ++P++ + P+ P++ PA
Sbjct: 600 APTTPE-ELAPTT-PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PA 656
Query: 1680 FVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVS 1739
P PT G A + EP P+ + P T K P
Sbjct: 657 PTTPKETAPT-TPKGTAPTTLKEPAPTTPKKPAPKELAPTT---------TKEPTSTTCD 706
Query: 1740 SPAKTVGRFSVVSTQDEWTLASPHSLRYSAP----PDVYLDEAPSSPDVKLAVRRAQTAS 1795
PA T + + +T E +P + P P + AP++P A T +
Sbjct: 707 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 766
Query: 1796 SIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGP 1855
G S P+ P + P + P + P
Sbjct: 767 K---GPTSTTSDKPAPTTPKETAPTTPKEPAPTT-----------------PKKPAPTTP 806
Query: 1856 ETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQS 1899
ETP +V T + T + ++ EL K L++
Sbjct: 807 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 850
Score = 38.1 bits (87), Expect = 0.097
Identities = 34/149 (22%), Positives = 53/149 (35%), Gaps = 8/149 (5%)
Query: 29 PRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAER 88
P+A+ GP + + +EP A+ P P ++ + +
Sbjct: 292 PKAETTTKGPALTTPKEPTPTTPKEP----ASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 347
Query: 89 ARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
A P PAP + AP P + P P T+EP P +A T P ++ A
Sbjct: 348 APTTPKEPAPTT--TKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403
Query: 149 ATVRKEDEGAAEAKPEPGRTRRDEPEEEE 177
T KE +P P + P +E
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKE 432
Score = 37.7 bits (86), Expect = 0.13
Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 3/81 (3%)
Query: 96 PAPAALVAQPGAPGAPADAGPE---PVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVR 152
PAP + P P PA P+ P +EP P T P +E A T
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438
Query: 153 KEDEGAAEAKPEPGRTRRDEP 173
KE A KP P + P
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAP 459
Score = 35.4 bits (80), Expect = 0.63
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 3/90 (3%)
Query: 87 ERARGRPAAPAPAALVA-QPGAPGAPADAGPE--PVGTQEPGPDPIAAAVETAPAPDGGP 143
E A P PAP P P PA + P T+EP P +A T P
Sbjct: 456 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515
Query: 144 REEAAATVRKEDEGAAEAKPEPGRTRRDEP 173
+E A T KE KP P + P
Sbjct: 516 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545
Score = 34.7 bits (78), Expect = 1.1
Identities = 43/176 (24%), Positives = 53/176 (30%), Gaps = 18/176 (10%)
Query: 7 RRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPG-- 64
+ P T EP P EP A P +S + +E P AP
Sbjct: 353 KEPAPTTTKEPA----PTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 407
Query: 65 --PQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQ 122
P P P + + E A P PAP A P P P P +
Sbjct: 408 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPTTPKEPAPTTPK 463
Query: 123 EPGPDPIAAAVETAPAPDGGPREEAAATVRKE-----DEGAAEAKPEPGRTRRDEP 173
EP P T P ++A T KE + A EP T EP
Sbjct: 464 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 519
Score = 34.3 bits (77), Expect = 1.4
Identities = 32/132 (24%), Positives = 45/132 (34%), Gaps = 4/132 (3%)
Query: 44 RSVVESDQEEPPGLEAAEAPG-PQPPQPLQRRVLLLCKTRRLIAERARGRPAAPA-PAAL 101
+S + +E P AP P+ P P + T+ P P PA
Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 102 VAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEA 161
+ AP P + P P +EP P A T P ++ A T KE
Sbjct: 406 TPKEPAPTTPKE--PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 463
Query: 162 KPEPGRTRRDEP 173
+P P T+ P
Sbjct: 464 EPAPTTTKEPSP 475
Score = 33.5 bits (75), Expect = 2.4
Identities = 38/174 (21%), Positives = 55/174 (31%), Gaps = 28/174 (16%)
Query: 19 RGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLL 78
+G P + EP A P++ + + + +EP + P P P+
Sbjct: 669 KGTAPTTLKEP----APTTPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGT------- 716
Query: 79 CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGP----EPVGTQEPGPDPIAAAVE 134
A P PAP + AP P P EP T P P A
Sbjct: 717 ----------APTTPKEPAPTT--PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 764
Query: 135 TAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVAT 188
T P ++ A T KE +P P ++ P E V+T
Sbjct: 765 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 112 bits (279), Expect = 5e-24
Identities = 127/476 (26%), Positives = 160/476 (33%), Gaps = 69/476 (14%)
Query: 674 QPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP---TGPGQPAPPGQQ 730
+ T+A L S P + PA++ P P P+TP T P +P P +
Sbjct: 314 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIK 372
Query: 731 PPPLAQPTPLPQVLAPQPVVPLQPVP-------PHLPPYLAPASQVGAPAQLKPLQMPQA 783
P P P P P +P P P P AP + PA P
Sbjct: 373 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTT 431
Query: 784 PLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSL 843
P +P P + P P P P PT T P P P PA P
Sbjct: 432 PKEPAPTTPKKPAPTTPKEP----------APTTPKEPTPTTPKEPAPTTKEPAPTTPKE 481
Query: 844 AAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAV 903
AP P PA P P P AP T + P A + +
Sbjct: 482 PAPTAPKKPAPTTPKEPAPTTPKEP-----------APTTTKEPSPTTPKEPAPTTTKSA 530
Query: 904 AQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP--PQPVLP--PQ 959
+P P T PSP T + TP +PA PT P P P P P
Sbjct: 531 PTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA----PTTPKKPAPTTPKEPA 585
Query: 960 PTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATP 1019
PT P +P P T+ P P P + P P P + A P P+ L P PE+ AP TP
Sbjct: 586 PTTPKEPA--PTTTKKPAPTTPKE----PAPTTPKETA-PTTPKKLTPTTPEKLAP-TTP 637
Query: 1020 GSQILLGHPAPYAVDVAAQVPTVPVPPAAVL----SPPLPEVLLPAAP-ELLPQFPSSLA 1074
PAP + A PT P P +P P+ P P E P P A
Sbjct: 638 EK------PAPTTPEELA--PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 689
Query: 1075 --TVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKP 1128
T + P +TA P P + P PT P + + +P
Sbjct: 690 PTTPKEPAPTTPKETAPTTPKGTAPTT----LKEPAPTTPKKPAPKELAPTTTKEP 741
Score = 108 bits (269), Expect = 8e-23
Identities = 155/632 (24%), Positives = 207/632 (32%), Gaps = 116/632 (18%)
Query: 602 TLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPV 661
T+ T T+ + T G+ T S QS+ S D AP+ V + P +
Sbjct: 283 TVETKETTTTNKQTSTDGKEKTT---SAKETQSIEKTSAKDLAPTSK--VLAKPTPKAET 337
Query: 662 LPQSLPSLGAYQQPT-AAPGLPVGSVPAPACPPSLQQHFPDP---------AMSFAPVLP 711
+ P+L ++PT P P + P P +++ P + P P
Sbjct: 338 TTKG-PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 396
Query: 712 PPST---PMPTGPGQPAPPGQQPP--------PLAQPTPLPQV-LAPQPVVPLQPVP--- 756
P+T P PT P +PAP + P P P P P P P +P P
Sbjct: 397 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 456
Query: 757 ----PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVP----PIT--- 805
P P AP ++ AP K P AP +P P + P P P P T
Sbjct: 457 KEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTTPKE--PAPTTPKEPAPTTTKE 513
Query: 806 --PLAGIDGLPPALPDLPTATVPPVP--------------PPQYFSPAVILPSLAAPLPP 849
P + P PT T P P P PA P AP P
Sbjct: 514 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 573
Query: 850 ASPALPLQAVKLPHPPGAPLAMPCRTIVPN-----APATIPLLAVAPPGVAALSIHSAVA 904
PA P P P + P AP T A P + +A
Sbjct: 574 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 633
Query: 905 QLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLP 957
+ P ++APT T + T P+ A P P PT P P P P
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 693
Query: 958 --PQPTLP------------PQPVLPPQPTRPPQPVLPPQPMLP-------------PQP 990
P PT P P + P PT P +P P+ + P P P
Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPTTTKEPTSTTCDKPAP 751
Query: 991 VLP--PQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQ---VPTVPVP 1045
P P P P P P P P T + L PAP A PT
Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGT--APTTLKEPAPTTPKKPAPKELAPTTTKG 809
Query: 1046 PAAVLS----PPLPEVLLPAAP-ELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPG 1100
P + S P P+ P P E P P A + ++ P T+ + P P
Sbjct: 810 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP--ETPPPTTSEVSTPTTTKEPT 867
Query: 1101 GPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
+ T +L+ EP + + K PG+P
Sbjct: 868 TIHKSPDESTPELSAEPTPKALENSPKEPGVP 899
Score = 94.7 bits (234), Expect = 9e-19
Identities = 135/582 (23%), Positives = 188/582 (32%), Gaps = 96/582 (16%)
Query: 586 PPEPEEPEADQHLLPPTLPT----SATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLA 641
P P+EP PT P + T + +T +T + ++ +S
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434
Query: 642 DAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQP---TAAPGLPVGSVPAPACPPSLQQH 698
A +P + + P P P+ P+ ++P T P PAP P
Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 493
Query: 699 FPDPAMSFAPVLPPPST---PMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV 755
P P P P+T P PT P +PAP + P P P P P +P
Sbjct: 494 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 553
Query: 756 P-------PHLPPYLAPASQVGAPAQLKPLQ----MPQAPLQPLAQVP-PQMP--PIPVV 801
P P P AP + PA P + P+ P + P P P P P
Sbjct: 554 PTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 612
Query: 802 PPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLA---APLPPASPALPLQA 858
P T L P P+ T P P P +P + P+ P P PA
Sbjct: 613 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPT--TPEELAPTTPEEPTPTTPEEPAPTTPK 670
Query: 859 VKLPHPPGAPLAMPCRTIVPNAPA----TIP--LLAVAPPGVAALSIHSAVAQLPGQPVY 912
P+ P P + P P T P P G A ++ P +P
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP-- 728
Query: 913 PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLP-------- 957
A ++APT T T P+ P P PT P P P P
Sbjct: 729 --APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 786
Query: 958 --PQPTLP-----------------------PQPVLPPQ--PTRPPQPVLPPQPMLPPQP 990
P PT P P P P + PT P +P P
Sbjct: 787 KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA----------P 836
Query: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVL 1050
P +PA P PE P E + P T + P +++A+ PT +
Sbjct: 837 TTPKKPA-PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE-PTPKALENSPK 894
Query: 1051 SPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP 1092
P +P PAA + + T +++ P +T T P
Sbjct: 895 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-ETTTAAP 935
Score = 89.0 bits (219), Expect = 5e-17
Identities = 110/471 (23%), Positives = 149/471 (31%), Gaps = 56/471 (11%)
Query: 583 QPGPPEPEEPEADQHLLPPTLPTSATSLA----SDSTFDSGQGSTVYSDSQSSQQSVMLG 638
+P P P+EP PT P A + +T +T + ++ +
Sbjct: 458 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 517
Query: 639 SLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAA--PGLPVGSVPAPACPPSLQ 696
+ + AP+ + + P +S P+ PT P PAP P
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 577
Query: 697 QHFPDPAMSFAPVLPPPST---PMPTGPGQPAPPGQQPPPLAQPTP------LPQVLAPQ 747
P P P P+T P PT P +PAP P A TP P+ LAP
Sbjct: 578 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT--TPKETAPTTPKKLTPTTPEKLAPT 635
Query: 748 ------PVVPLQPVP-------PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ 794
P P + P P P AP + A P P +P P +
Sbjct: 636 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695
Query: 795 MPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPAL 854
P P P T G P P T P P P+ +P + +P
Sbjct: 696 --PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 753
Query: 855 PLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPA 914
P P P P P PA P G A ++ P +P
Sbjct: 754 PKGTA--PTTPKEP-----APTTPKEPA-----PTTPKGTAPTTLKEPAPTTPKKP---- 797
Query: 915 AFPQMAPTDVPPSPHHTVQNMRATPPQPALP-----PQPTLP--PQPVLPPQPTLPPQPV 967
A ++APT T T P+ P P PT P P P P P V
Sbjct: 798 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 857
Query: 968 LPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT 1018
P T+ P + P+ P P + P +P +P PAAT
Sbjct: 858 STPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTKTPAAT 907
Score = 72.0 bits (175), Expect = 6e-12
Identities = 81/389 (20%), Positives = 122/389 (31%), Gaps = 43/389 (11%)
Query: 583 QPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLAD 642
+P P P+EP P PT+ A + + +T + ++
Sbjct: 559 EPAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 616
Query: 643 AAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702
A +P + + P P P+ + P P + P P + + P+
Sbjct: 617 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 676
Query: 703 AMSFAPVLPPPSTPMPTGPGQPAP--PGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLP 760
AP P P PT P +PAP P + P + T + P P P +P P L
Sbjct: 677 PKEPAPTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 734
Query: 761 PYLA---PASQVGAPAQLKPL-QMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPA 816
P ++ PA P P P +P P + P P P G P
Sbjct: 735 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTP--------KGTAPT 784
Query: 817 LPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTI 876
P T P P P+ +P + +P P + P P P +
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKEPAPTTPKKP 842
Query: 877 VPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMR 936
P P T PP + +S + + PT + SP + +
Sbjct: 843 APTTPET------PPPTTSEVSTPTTTKE---------------PTTIHKSPDESTPELS 881
Query: 937 ATPPQPALPPQPTLPPQPVLPPQPTLPPQ 965
A P AL P P P P+
Sbjct: 882 AEPTPKALENSPKEPGVPTTKTPAATKPE 910
Score = 67.8 bits (164), Expect = 1e-10
Identities = 120/567 (21%), Positives = 184/567 (32%), Gaps = 100/567 (17%)
Query: 568 PVPLQVQVTYHAQAGQPGPPEPEE----------PEADQHLLPPT----LPTSATSLASD 613
P P + +P P P+E P + L P T PT+ LA
Sbjct: 592 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP- 650
Query: 614 STFDSGQGSTVYSDSQSSQQSVMLGSLADAAPS-PAQCVCSPPVSEGPVLP-QSLPSLGA 671
+T + +T + ++ ++ + + AP+ P + + P P P ++ P+
Sbjct: 651 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 710
Query: 672 YQQPTA----APGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPP---PSTPMPTGPGQP 724
PT AP P P P + ++ AP P P+TP P P
Sbjct: 711 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 770
Query: 725 APPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLA--PASQVG-APAQLKPLQM- 780
P P PT L + P P P +P P L P P S PA P +
Sbjct: 771 KEPAPTTPKGTAPTTLKE---PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 827
Query: 781 PQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
P P +P P + P P P TP PP ++ T T P + SP
Sbjct: 828 PTTPKEPAPTTPKK--PAPTTPE-TP-------PPTTSEVSTPTTTKEPTTIHKSPDEST 877
Query: 841 PSLAA-PLP------PASPALPLQAVKLPHPPGAPLAMPCRTI------VPNAPATIPLL 887
P L+A P P P P +P P +T P P +
Sbjct: 878 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 937
Query: 888 AVAPPGVAALSIHSAVAQLPGQ-----------------------PVYPAAFPQMAPTDV 924
+ S + Q P + T++
Sbjct: 938 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI 997
Query: 925 PPSPHHTVQ------NMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQP 978
P T + N +AT P+P P + P +PT +P P+ R P+
Sbjct: 998 MNKPEETAKPKDRATNSKATTPKPQKPTK--------APKKPTSTKKPKTMPR-VRKPKT 1048
Query: 979 VLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP-APYAVDVAA 1037
P+ M P L P + + L P TP S+++ +P + A
Sbjct: 1049 TPTPRKMTSTMPELNPTSRI------AEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEG 1102
Query: 1038 QVPTVPVPPAAVLSPPLPEV-LLPAAP 1063
+ P + + P + P++ LP P
Sbjct: 1103 ETPHMLLRPHVFMPEVTPDMDYLPRVP 1129
Score = 67.4 bits (163), Expect = 1e-10
Identities = 129/644 (20%), Positives = 207/644 (32%), Gaps = 62/644 (9%)
Query: 1275 TSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLP 1334
T+ ST G ++++Q+ +++ T K P AE ++P P
Sbjct: 291 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP 350
Query: 1335 LSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAP-------PAPLAPS 1387
+ P E + + + K P+ + P P PAP P
Sbjct: 351 TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 410
Query: 1388 SPPVTALPQDGAAPATS----TMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAP 1443
P T + AP T+ T P+ + T + P TP+ E + P T P
Sbjct: 411 EPAPTTTKEP--APTTTKSAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPTPTTP 464
Query: 1444 LAVQPLVVGLAPCTP---APEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLL 1500
P AP TP AP A + P+EP P EP+P + T +P+ P
Sbjct: 465 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP-TTTKEPSPTTPKEPA 523
Query: 1501 PAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLL 1560
P + T + P+P + P P + + P P + +K
Sbjct: 524 PTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKKPAPTT 580
Query: 1561 YQEHVPTS-SASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLP 1619
+E PT+ A T + EP + P P++ + P
Sbjct: 581 PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 640
Query: 1620 QPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPA 1679
P + ELAPT T+ A ++P++ + P+ P++ PA
Sbjct: 641 APTTPE-ELAPTT-PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PA 697
Query: 1680 FVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVS 1739
P PT G A + EP P+ + P T K P
Sbjct: 698 PTTPKETAPT-TPKGTAPTTLKEPAPTTPKKPAPKELAPTT---------TKEPTSTTCD 747
Query: 1740 SPAKTVGRFSVVSTQDEWTLASPHSLRYSAP----PDVYLDEAPSSPDVKLAVRRAQTAS 1795
PA T + + +T E +P + P P + AP++P A T +
Sbjct: 748 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 807
Query: 1796 SIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGP 1855
G S P+ P + P + P + P
Sbjct: 808 K---GPTSTTSDKPAPTTPKETAPTTPKEPAPTT-----------------PKKPAPTTP 847
Query: 1856 ETPSRVGMKVPTISVTSFHSQSSYISSDNDSELEDADIKKELQS 1899
ETP +V T + T + ++ EL K L++
Sbjct: 848 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 891
Score = 38.1 bits (87), Expect = 0.097
Identities = 34/149 (22%), Positives = 53/149 (35%), Gaps = 8/149 (5%)
Query: 29 PRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAER 88
P+A+ GP + + +EP A+ P P ++ + +
Sbjct: 333 PKAETTTKGPALTTPKEPTPTTPKEP----ASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 388
Query: 89 ARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
A P PAP + AP P + P P T+EP P +A T P ++ A
Sbjct: 389 APTTPKEPAPTT--TKEPAPTTPKE--PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444
Query: 149 ATVRKEDEGAAEAKPEPGRTRRDEPEEEE 177
T KE +P P + P +E
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKE 473
Score = 37.7 bits (86), Expect = 0.13
Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 3/81 (3%)
Query: 96 PAPAALVAQPGAPGAPADAGPE---PVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVR 152
PAP + P P PA P+ P +EP P T P +E A T
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479
Query: 153 KEDEGAAEAKPEPGRTRRDEP 173
KE A KP P + P
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAP 500
Score = 35.4 bits (80), Expect = 0.63
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 3/90 (3%)
Query: 87 ERARGRPAAPAPAALVA-QPGAPGAPADAGPE--PVGTQEPGPDPIAAAVETAPAPDGGP 143
E A P PAP P P PA + P T+EP P +A T P
Sbjct: 497 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556
Query: 144 REEAAATVRKEDEGAAEAKPEPGRTRRDEP 173
+E A T KE KP P + P
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586
Score = 34.7 bits (78), Expect = 1.1
Identities = 43/176 (24%), Positives = 53/176 (30%), Gaps = 18/176 (10%)
Query: 7 RRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPG-- 64
+ P T EP P EP A P +S + +E P AP
Sbjct: 394 KEPAPTTTKEPA----PTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 448
Query: 65 --PQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQ 122
P P P + + E A P PAP A P P P P +
Sbjct: 449 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----PKKPAPTTPKEPAPTTPK 504
Query: 123 EPGPDPIAAAVETAPAPDGGPREEAAATVRKE-----DEGAAEAKPEPGRTRRDEP 173
EP P T P ++A T KE + A EP T EP
Sbjct: 505 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 560
Score = 34.3 bits (77), Expect = 1.4
Identities = 32/132 (24%), Positives = 45/132 (34%), Gaps = 4/132 (3%)
Query: 44 RSVVESDQEEPPGLEAAEAPG-PQPPQPLQRRVLLLCKTRRLIAERARGRPAAPA-PAAL 101
+S + +E P AP P+ P P + T+ P P PA
Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 102 VAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEA 161
+ AP P + P P +EP P A T P ++ A T KE
Sbjct: 447 TPKEPAPTTPKE--PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Query: 162 KPEPGRTRRDEP 173
+P P T+ P
Sbjct: 505 EPAPTTTKEPSP 516
Score = 33.5 bits (75), Expect = 2.4
Identities = 38/174 (21%), Positives = 55/174 (31%), Gaps = 28/174 (16%)
Query: 19 RGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLL 78
+G P + EP A P++ + + + +EP + P P P+
Sbjct: 710 KGTAPTTLKEP----APTTPKKPAPKELAPTTTKEPTST-TCDKPAPTTPKGT------- 757
Query: 79 CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGP----EPVGTQEPGPDPIAAAVE 134
A P PAP + AP P P EP T P P A
Sbjct: 758 ----------APTTPKEPAPTT--PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 805
Query: 135 TAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVAT 188
T P ++ A T KE +P P ++ P E V+T
Sbjct: 806 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 111 bits (278), Expect = 7e-24
Identities = 149/553 (26%), Positives = 185/553 (33%), Gaps = 111/553 (20%)
Query: 675 PTAA---PGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLP-PPSTPMPTGPGQPAPPGQQ 730
PTA P L G+ +P PP+L+ H + +P P P P + APP
Sbjct: 953 PTAGKLGPTLGAGTTRSPGSPPTLRVH----GDTGSPRKPWPERRPPRPAATRTAPPTPS 1008
Query: 731 PPPLAQPTPLPQVLAPQPVVPLQP-----------VPPHLPPYLAPASQVGAPAQLKP-- 777
P P A P P L L P P PP PAS+ L
Sbjct: 1009 PGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPD 1068
Query: 778 --LQMPQAPLQPLAQVPPQMPPIPVVP------PITPLAGIDGLPPALPDLPTA-TVPPV 828
L P + + P P P+P +P P TP + + L P +P + T P +
Sbjct: 1069 FALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTP-SEVTSLSPTSEQVPESDTTPDL 1127
Query: 829 PPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHP---------PGAPLAMPCRTIVPN 879
Y S P P P P P P P P T P+
Sbjct: 1128 DTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTT-PHPTTTPH 1186
Query: 880 APATIPLLAVAP-----PGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVP--------- 925
P TI + P P HS + +P P F M PT P
Sbjct: 1187 -PTTITHSTMIPDPTTTPQPFTTITHSTM--IPDPTTTPQPFTTMQPTTTPHSTTPHPTT 1243
Query: 926 -PSP----HHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVL 980
P P H T+ T PQP QPT P P P PT P P P PT P P +
Sbjct: 1244 TPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTM 1303
Query: 981 PPQPMLPPQPVLPPQPAL---PVRPEPLQP------HLPEQ---------AAPAATPGSQ 1022
P P P P P P P P+P LP AP P
Sbjct: 1304 TPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLH 1363
Query: 1023 ILLGHPAPYAVDVAAQVPTVPVPPAAVLSP----------PL-PEVLLP---AAPELLP- 1067
L AP +Q+PT+ PA SP PL E P +P L P
Sbjct: 1364 PQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPP 1423
Query: 1068 --QFPSSLATVSASVQSVPTQTATLL--PPANP----PLPG-GPGIASPCPTVQLTVEPV 1118
P S + ++ S + + TA L PP +P P PG PG PC V P
Sbjct: 1424 PTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPC------VAPT 1477
Query: 1119 QEEQASQDKPPGL 1131
+ +PP L
Sbjct: 1478 PPVRVMACEPPAL 1490
Score = 84.0 bits (206), Expect = 2e-15
Identities = 123/470 (26%), Positives = 158/470 (33%), Gaps = 76/470 (16%)
Query: 598 LLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVS 657
L P PT +L + T D S V S S +S+Q + D +P S VS
Sbjct: 1082 LTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTP----YSSTVS 1137
Query: 658 EGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHF---PDPAMSFAPVLPPPS 714
E P PS PT P + P P++ HF P P + P S
Sbjct: 1138 EYSRSPDPSPS----PHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHS 1193
Query: 715 T--PMPTGPGQPAPPGQQPPPLAQPTPLPQVLAP-QPVVPLQPVPPHLPPYLAPASQVGA 771
T P PT QP + PT PQ QP PH P + +
Sbjct: 1194 TMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHS 1253
Query: 772 PAQLKPLQMPQ--APLQPLAQVPPQMPPIPVV---PPITPLAGIDGLPPALPDLPTATVP 826
P PQ +QP P P P P TP P PD PT T
Sbjct: 1254 TMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPD-PTTTPY 1312
Query: 827 PVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPL 886
P P P P P ++P + V LP G L+ P T+ P
Sbjct: 1313 PTTTPD----PTTTPHPTTPDPSSTPV--ITTVSLPTSLGTELSSP--TLAPT------- 1357
Query: 887 LAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPP 946
V P+ PQ+ T P+PH + + P PAL
Sbjct: 1358 ------------------------VKPSLHPQL--TFTAPAPHTSTSQIPTLEPSPALES 1391
Query: 947 QP----TLPPQPVLPPQPTLPPQ---PVLPPQPTRPPQP----VLPPQPMLPP--QPV-L 992
P T L + PP+ P L P PT P + P P+L P P+
Sbjct: 1392 SPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDH 1451
Query: 993 PPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTV 1042
PP L + P P Q P A TP +++ P P V++ A V V
Sbjct: 1452 PPLDPLTLGPTPGQSPGPHGPCVAPTPPVRVMACEP-PALVELVAAVRDV 1500
Score = 44.7 bits (104), Expect = 0.001
Identities = 51/221 (23%), Positives = 77/221 (34%), Gaps = 18/221 (8%)
Query: 1330 SPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSP 1389
S +P + P+ P S+ P+ ++ + P P P P
Sbjct: 1212 STMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQP 1271
Query: 1390 PVTALPQDGAAPATSTMPEPASGTASQAGGPG---TPQGLTSELETSQPLAETHEAPLAV 1446
T +P P +T P P + T P TP T+ T+ P T P
Sbjct: 1272 --TTMPHPTTTPHPTTTPHPTT-TPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTP 1328
Query: 1447 QPLVVGLAPCTPAPEAASTRDASAPREPLPPPA-------PEPSPHSGTPQPALGQPAPL 1499
P + P + T +S P P+ P+PH+ T Q +P+P
Sbjct: 1329 DPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPA 1388
Query: 1500 LPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPP 1540
L ++ S ATS P T +PP + +S PPP
Sbjct: 1389 LESSPSRSSTATSMDPL----STEDFKPPRS-QSPNLTPPP 1424
Score = 44.3 bits (103), Expect = 0.001
Identities = 46/205 (22%), Positives = 70/205 (34%), Gaps = 15/205 (7%)
Query: 1327 PESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP--PGAPPAPL 1384
PE SP PL +LP E + D + PS + S S+ P + P P
Sbjct: 1084 PEPSPT-PLPTLPKELTSDPST----------PSEVTSLSPTSEQVPESDTTPDLDTTPY 1132
Query: 1385 APSSPPVTALPQDGAAPATSTMPEP--ASGTASQAGGPGTPQGLTSELETSQPLAETHEA 1442
+ + + P +P +T P+P A + TP T+ T+ P T
Sbjct: 1133 SSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITH 1192
Query: 1443 PLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPA 1502
+ P T + D + +P P +PHS TP P +
Sbjct: 1193 STMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITH 1252
Query: 1503 AVGAVSLATSQLPSPPLGPTVPPQP 1527
+ T+ P + PT P P
Sbjct: 1253 STMIPDPTTTPQPFTTMQPTTMPHP 1277
Score = 44.3 bits (103), Expect = 0.001
Identities = 63/249 (25%), Positives = 89/249 (35%), Gaps = 50/249 (20%)
Query: 1327 PESSPPLPLSSLPPEASQDSAPYKDQLSSKE-----QPSFLASQQLLSQAGPSNPPGAPP 1381
P S+ P P ++ P S D ++ + QP+ + P+ P
Sbjct: 1234 PHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPH--PTTTPHPTT 1291
Query: 1382 APLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGT---------PQGLTSELET 1432
P ++P T P P +T P+P + P + P L +EL +
Sbjct: 1292 TPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTEL-S 1350
Query: 1433 SQPLAETHEAPLAVQPLVVGLAPCT-----------PAPEAA-------------STRDA 1468
S LA T + L Q AP T PA E++ ST D
Sbjct: 1351 SPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDF 1410
Query: 1469 SAPREPLP--PPAPEPSPHSG-----TPQPALGQPA-PLLPAAVGAVSLATSQLPSP-PL 1519
PR P P P +PHS +P P L A PL + ++L + SP P
Sbjct: 1411 KPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPH 1470
Query: 1520 GPTVPPQPP 1528
GP V P PP
Sbjct: 1471 GPCVAPTPP 1479
Score = 43.9 bits (102), Expect = 0.002
Identities = 48/170 (28%), Positives = 67/170 (39%), Gaps = 22/170 (12%)
Query: 1376 PPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTP-QGLTSELETSQ 1434
P PP P A + P T P A+P P S + TP LTSE +
Sbjct: 990 PERRPPRPAATRTAPPTPSPGPSASPG-----PPGPALTSDSSRELTPHSALTSEATSDA 1044
Query: 1435 P--LAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPA 1492
P T + P ++ +P A ST D+S +P PEPSP TP P
Sbjct: 1045 PDTSPPTPDPASRTNPDLILTSP----DFALSTPDSSV----VPALTPEPSP---TPLPT 1093
Query: 1493 LGQPA---PLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP 1539
L + P P+ V ++S + Q+P P + P S+ S+ P
Sbjct: 1094 LPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSP 1143
Score = 41.6 bits (96), Expect = 0.009
Identities = 56/212 (26%), Positives = 77/212 (36%), Gaps = 22/212 (10%)
Query: 1452 GLAPCTP-APEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLA 1510
GLA TP A + T A R P PP +G+P+ + P PAA
Sbjct: 947 GLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAP-- 1004
Query: 1511 TSQLPSPPLGPTVPPQPPS-ALESDG--EGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPT 1567
P+P GP+ P PP AL SD E P ++T + D T P
Sbjct: 1005 ----PTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPT-------PD 1053
Query: 1568 SSASAGTPVEVGDRDFTLE-PLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKS 1626
++ + + DF L P P LP +PKE S P E +
Sbjct: 1054 PASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSD----PSTPSEVT 1109
Query: 1627 ELAPTRGAVMEQGTSSSMTAESSPRSMLGYDR 1658
L+PT V E T+ + ++ Y R
Sbjct: 1110 SLSPTSEQVPESDTTPDLDTTPYSSTVSEYSR 1141
>gi|42794767 mitogen-activated protein kinase kinase kinase 3
isoform 1 [Homo sapiens]
Length = 657
Score = 111 bits (278), Expect = 7e-24
Identities = 84/261 (32%), Positives = 133/261 (50%), Gaps = 16/261 (6%)
Query: 201 LGRGSFKTVYKGLDTETWVEVAWCELQ---DRKLTKLERQRFKEEAEMLKGLQHPNIVRF 257
LG+G+F VY D +T E+A ++Q D T E + E ++LK LQH IV++
Sbjct: 399 LGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQY 458
Query: 258 YDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTP 317
Y A+ + + + E M G++K LK + + V R + RQIL+G+ +LH+
Sbjct: 459 YGCLRDRAE--KTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNM- 515
Query: 318 PIIHRDLKCDNIFITGPTGSVKIGDLG----LATL-KRASFAKSVIGTPEFMAPEMYE-E 371
I+HRD+K NI + G+VK+GD G L T+ + +SV GTP +M+PE+ E
Sbjct: 516 -IVHRDIKGANI-LRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGE 573
Query: 372 HYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIG 431
Y DV++ G ++EM T + P++E + A I++ T P H E
Sbjct: 574 GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQL--PSHISEHGRDFL 631
Query: 432 ECICKNKEERYEIKDLLSHAF 452
I +R ++LL+H F
Sbjct: 632 RRIFVEARQRPSAEELLTHHF 652
>gi|42794765 mitogen-activated protein kinase kinase kinase 3
isoform 2 [Homo sapiens]
Length = 626
Score = 111 bits (278), Expect = 7e-24
Identities = 84/261 (32%), Positives = 133/261 (50%), Gaps = 16/261 (6%)
Query: 201 LGRGSFKTVYKGLDTETWVEVAWCELQ---DRKLTKLERQRFKEEAEMLKGLQHPNIVRF 257
LG+G+F VY D +T E+A ++Q D T E + E ++LK LQH IV++
Sbjct: 368 LGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQY 427
Query: 258 YDFWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTP 317
Y A+ + + + E M G++K LK + + V R + RQIL+G+ +LH+
Sbjct: 428 YGCLRDRAE--KTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNM- 484
Query: 318 PIIHRDLKCDNIFITGPTGSVKIGDLG----LATL-KRASFAKSVIGTPEFMAPEMYE-E 371
I+HRD+K NI + G+VK+GD G L T+ + +SV GTP +M+PE+ E
Sbjct: 485 -IVHRDIKGANI-LRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGE 542
Query: 372 HYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIG 431
Y DV++ G ++EM T + P++E + A I++ T P H E
Sbjct: 543 GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQL--PSHISEHGRDFL 600
Query: 432 ECICKNKEERYEIKDLLSHAF 452
I +R ++LL+H F
Sbjct: 601 RRIFVEARQRPSAEELLTHHF 621
>gi|222418622 NIMA-related kinase 6 isoform 1 [Homo sapiens]
Length = 347
Score = 110 bits (276), Expect = 1e-23
Identities = 87/265 (32%), Positives = 139/265 (52%), Gaps = 30/265 (11%)
Query: 197 FDIE--LGRGSFKTVYKG---LDTETWV--EVAWCELQDRKLTKLERQRFKEEAEMLKGL 249
F IE +GRG F VYK LD +T +V E+ D K RQ +E +LK L
Sbjct: 79 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKA----RQDCVKEIGLLKQL 134
Query: 250 QHPNIVRFYD-FWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMK----PKVLRSWCRQ 304
HPNI+++ D F E + + +V EL +G L +K FK K + + + Q
Sbjct: 135 NHPNIIKYLDSFIEDNE-----LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQ 189
Query: 305 ILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATL--KRASFAKSVIGTPE 362
+ + +H+R ++HRD+K N+FIT TG VK+GDLGL + A S++GTP
Sbjct: 190 LCSAVEHMHSRR--VMHRDIKPANVFITA-TGVVKLGDLGLGRFFSSETTAAHSLVGTPY 246
Query: 363 FMAPE-MYEEHYDESVDVYAFGMCMLEMATSEYP-YSECQNAAQIYRKV-TCGIKPASFE 419
+M+PE ++E Y+ D+++ G + EMA + P Y + N + +K+ C P E
Sbjct: 247 YMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGE 306
Query: 420 KVHDPEIKEIIGECICKNKEERYEI 444
+ +++E++ CIC + +R +I
Sbjct: 307 H-YSEKLRELVSMCICPDPHQRPDI 330
>gi|19923407 NIMA-related kinase 6 isoform 2 [Homo sapiens]
Length = 313
Score = 110 bits (276), Expect = 1e-23
Identities = 87/265 (32%), Positives = 139/265 (52%), Gaps = 30/265 (11%)
Query: 197 FDIE--LGRGSFKTVYKG---LDTETWV--EVAWCELQDRKLTKLERQRFKEEAEMLKGL 249
F IE +GRG F VYK LD +T +V E+ D K RQ +E +LK L
Sbjct: 45 FQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKA----RQDCVKEIGLLKQL 100
Query: 250 QHPNIVRFYD-FWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMK----PKVLRSWCRQ 304
HPNI+++ D F E + + +V EL +G L +K FK K + + + Q
Sbjct: 101 NHPNIIKYLDSFIEDNE-----LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQ 155
Query: 305 ILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATL--KRASFAKSVIGTPE 362
+ + +H+R ++HRD+K N+FIT TG VK+GDLGL + A S++GTP
Sbjct: 156 LCSAVEHMHSRR--VMHRDIKPANVFITA-TGVVKLGDLGLGRFFSSETTAAHSLVGTPY 212
Query: 363 FMAPE-MYEEHYDESVDVYAFGMCMLEMATSEYP-YSECQNAAQIYRKV-TCGIKPASFE 419
+M+PE ++E Y+ D+++ G + EMA + P Y + N + +K+ C P E
Sbjct: 213 YMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGE 272
Query: 420 KVHDPEIKEIIGECICKNKEERYEI 444
+ +++E++ CIC + +R +I
Sbjct: 273 H-YSEKLRELVSMCICPDPHQRPDI 296
>gi|4507831 Unc-51-like kinase 1 [Homo sapiens]
Length = 1050
Score = 110 bits (274), Expect = 2e-23
Identities = 178/713 (24%), Positives = 270/713 (37%), Gaps = 130/713 (18%)
Query: 201 LGRGSFKTVYKGLDTETW-VEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYD 259
+G G+F V+KG E +EVA + + L K + KE ++LK L+H NIV YD
Sbjct: 22 IGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKE-IKILKELKHENIVALYD 80
Query: 260 FWESSAKGKRCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPI 319
F E + + LV E G L YL + + +R + +QI + LH++ I
Sbjct: 81 FQEMA----NSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSK--GI 134
Query: 320 IHRDLKCDNIFITGPTG--------SVKIGDLGLAT-LKRASFAKSVIGTPEFMAPE-MY 369
IHRDLK NI ++ P G VKI D G A L+ A ++ G+P +MAPE +
Sbjct: 135 IHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIM 194
Query: 370 EEHYDESVDVYAFGMCMLEMATSEYPY--SECQNAAQIYRKVTCGIKPASFEKVHDPEIK 427
+HYD D+++ G + + T + P+ S Q+ Y K + P + P ++
Sbjct: 195 SQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEK-NKTLVPTIPRETSAP-LR 252
Query: 428 EIIGECICKNKEERYEIKDLLSHAFFAEDTGVR-------VELAEEDHGRKSTIALRLWV 480
+++ + +N ++R + + H F VR G S+ + +
Sbjct: 253 QLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHL 312
Query: 481 EDPKKLKGKPKDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSI---RDRVA 537
P L G ++ L+K +A +GF H S +K D
Sbjct: 313 ASPPSL-------GEMQ---QLQK----TLASPADTAGFLHSSRDSGGSKDSSCDTDDFV 358
Query: 538 LIQWRRERIWPALQPKEQQDVGSPDKARGPPVPLQVQ---------VTYHAQAGQPGPPE 588
++ PA P + V A+ PP L + H + P PP
Sbjct: 359 MV--------PAQFPGDL--VAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPC 408
Query: 589 PEEPEADQHL-----------LPPTLPTSA-------TSLASDSTFDSGQGSTVYSDSQS 630
P +P +PT +L S + F + + S + +
Sbjct: 409 SSSPSPSGRAGPFSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSGST 468
Query: 631 SQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPA 690
S LG A A+PSP G VL + + SLG + T +P VG++P
Sbjct: 469 SP----LG-FARASPSP-----PAHAEHGGVLARKM-SLGGGRPYTPSP--QVGTIP--- 512
Query: 691 CPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQP-V 749
P S P P G P P P + + L L P +
Sbjct: 513 ---------ERPGWSGT---PSPQGAEMRGGRSPRPGSSAPEHSPRTSGLGCRLHSAPNL 560
Query: 750 VPLQPVPPHLP-PYLAPASQVGAPAQLKPLQMPQAPLQPLAQV--PPQMPPIPVVPPITP 806
L V P LP P P V +P Q P Q P LQ + P++P P+ P
Sbjct: 561 SDLHVVRPKLPKPPTDPLGAVFSPPQASPPQ-PSHGLQSCRNLRGSPKLPDFLQRNPLPP 619
Query: 807 LAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLA----APLPPASPALP 855
+ G PT VP P+ S +L LA PP + LP
Sbjct: 620 ILG----------SPTKAVPSFDFPKTPSSQNLLALLARQGVVMTPPRNRTLP 662
Score = 34.3 bits (77), Expect = 1.4
Identities = 101/452 (22%), Positives = 141/452 (31%), Gaps = 29/452 (6%)
Query: 699 FPDPAMSFAP-VLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPP 757
FP ++ AP PPP + M +G A G + TP P P P
Sbjct: 364 FPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGR---TPSPSPPCSSSPSPSGRAGP 420
Query: 758 HLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVP-PQMPPIPVVPPITPLAGIDGLPPA 816
+ + P Q++ Q + LQ Q P+ I +PL G A
Sbjct: 421 FSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSGSTSPL----GFARA 476
Query: 817 LPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLA-----M 871
P P + S P +P P P + P P GA +
Sbjct: 477 SPSPPAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWS-GTPSPQGAEMRGGRSPR 535
Query: 872 PCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHT 931
P + ++P T L +H +LP P P P PP P H
Sbjct: 536 PGSSAPEHSPRTSGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGAVFSPPQASPPQPSHG 595
Query: 932 VQNMRATPPQPALPPQPTLPPQPVLPPQPT-LPPQPVLPPQPTRPPQPVLPPQP---MLP 987
+Q+ R P LP P P + PT P P P+ L + M P
Sbjct: 596 LQSCRNLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQGVVMTP 655
Query: 988 PQ-PVLPPQPAL-PVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVP 1045
P+ LP + P +PL P L P G + AA P P
Sbjct: 656 PRNRTLPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLK-AAFGTQAPDP 714
Query: 1046 PAAVLSPPLPEVLLPAA-------PELLPQFPSSLATVSASVQSVPTQTATLLPPANPPL 1098
+ P + P+A P SS + V +V S P+ + P
Sbjct: 715 GSTESLQEKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPRTRMF 774
Query: 1099 PGGPGIASPCPTVQLTVEPVQEEQASQDKPPG 1130
GP ++ L P E A + PG
Sbjct: 775 SAGPTGSASSSARHLVPGPCSEAPAPELPAPG 806
Score = 32.7 bits (73), Expect = 4.1
Identities = 58/245 (23%), Positives = 85/245 (34%), Gaps = 44/245 (17%)
Query: 1318 VAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP---S 1374
VAE P+ + P S SSL A +S + P +S +AGP S
Sbjct: 369 VAEAPSAKPPPDSLMCSGSSLVASAGLES----HGRTPSPSPPCSSSPSPSGRAGPFSSS 424
Query: 1375 NPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQ 1434
+ P P+ + ++ +P P +A + G +P G + S
Sbjct: 425 RCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPR---SSAIRRSGSTSPLGF-ARASPSP 480
Query: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPEA-----------------ASTRDASAPREPLPP 1477
P H LA + + G P TP+P+ A R +PR
Sbjct: 481 PAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWSGTPSPQGAEMRGGRSPRP--GS 538
Query: 1478 PAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGP---------TVPPQPP 1528
APE SP + LG P + + + +LP PP P PPQP
Sbjct: 539 SAPEHSPRTS----GLGCRLHSAP-NLSDLHVVRPKLPKPPTDPLGAVFSPPQASPPQPS 593
Query: 1529 SALES 1533
L+S
Sbjct: 594 HGLQS 598
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 108 bits (270), Expect = 6e-23
Identities = 131/479 (27%), Positives = 174/479 (36%), Gaps = 90/479 (18%)
Query: 708 PVLPPPSTPM-PTGPGQPAPPGQQPP--PLAQPTPLPQVLAPQPVVPLQ----PVPP--- 757
P L P P+ P P P PP QQ P L QP PL QP++P+Q P PP
Sbjct: 306 PALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPL------QPLLPVQHPHHPSPPQGM 359
Query: 758 HLPPYLAPASQVGAPAQLKPLQMPQAPLQP----LAQVPPQMPPIPVVPPITPLAGIDGL 813
H+PP L + P + P Q + P P Q+P +PV P G
Sbjct: 360 HMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRF 419
Query: 814 PPALPDLPTATVPPVP-------------------PPQ-------------YFSPAVILP 841
P P+ P T PVP PPQ F + L
Sbjct: 420 PGP-PEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLE 478
Query: 842 SLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTI-----VPNAPATIPLL-AVAPPGVA 895
+ P PP P L + +P P P P P P+ A+ PPG
Sbjct: 479 QRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPV 538
Query: 896 ALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPV 955
+ S +P P P + P P HT N++ P PP P QP
Sbjct: 539 GILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQ 598
Query: 956 L--PPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQP---------VLPPQPALPVRPEP 1004
PPQ P QP P P P P PPQ PPQ +PP P +P+
Sbjct: 599 QQPPPQHQPPHQPPHQPPPQHQPPPQHPPQH--PPQHQHHHHHHHLSVPPPPLMPMSQPQ 656
Query: 1005 LQPHLPEQAAPAAT------PGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVL 1058
+PH+ + A P A+ P Q L + V ++ P + P A + L E
Sbjct: 657 FRPHV-QTAQPQASSSRMQCPQRQGLRHNTTSQNV---SKRPMQQMQPTAPRNSNLRE-- 710
Query: 1059 LPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEP 1117
LP AP + + SS + + S Q P + A+PP G S ++ V+P
Sbjct: 711 LPIAPSHVIEMSSSRCSATPSAQVKP------IVSASPPSRAVAGSRSSQGKTEVKVKP 763
Score = 60.5 bits (145), Expect = 2e-08
Identities = 120/500 (24%), Positives = 161/500 (32%), Gaps = 69/500 (13%)
Query: 550 LQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPE-PEE---PEADQHLLPPTLPT 605
+ P + V +P + PVP Q + Q PGPPE P+ P + PP LP
Sbjct: 387 INPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRF-PGPPEFPQHTPGPVPNSFSQPPRLPL 445
Query: 606 SATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVC--SPPVSEGPVLP 663
A D S + L + P P + S PV LP
Sbjct: 446 QDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLP 505
Query: 664 QSLPSLGAYQQ---PTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 720
+ P QQ P PV P P + HF P + PP P G
Sbjct: 506 FTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGIL-HFSQPGSATTRPFIPPRQPFLPG 564
Query: 721 PGQPAPPGQQPPPLAQPT--PLPQVLAPQPVVPLQPVP---------PHLPPYLAPASQV 769
PGQP P P L P PLP PQP P Q P PH PP
Sbjct: 565 PGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPP-------- 616
Query: 770 GAPAQLKPLQMPQAPLQPLAQVPPQMPP------------IPVVPPITPLAGIDGLPPAL 817
PQ QP Q PPQ PP +P PP+ P++ P
Sbjct: 617 -----------PQH--QPPPQHPPQHPPQHQHHHHHHHLSVP-PPPLMPMSQPQFRPHVQ 662
Query: 818 PDLPTATVPPVPPPQYFSPAVILPS---LAAPLPPASPALPLQA--VKLPHPPGAPLAMP 872
P A+ + PQ S P+ P P + +LP P + M
Sbjct: 663 TAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMS 722
Query: 873 CRTIVPNAPATI-PLLAVAPPGVAALSIHSA--VAQLPGQPVYPAAFPQ---MAPTDVPP 926
A + P+++ +PP A S+ ++ +P P A P+ T+ P
Sbjct: 723 SSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPD 782
Query: 927 SPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPML 986
T Q L + + Q + +L + Q PP P
Sbjct: 783 EDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAE 842
Query: 987 PPQPVLPPQP--ALPVRPEP 1004
+ L P P P+ P P
Sbjct: 843 QEEQALSPSPTNGNPLLPFP 862
Score = 48.5 bits (114), Expect = 7e-05
Identities = 59/223 (26%), Positives = 72/223 (32%), Gaps = 32/223 (14%)
Query: 1322 PAPEAPESSPPLPLSSL--PPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGA 1379
P P + P LPL P QD P+ L +P F S L Q P PP
Sbjct: 432 PVPNSFSQPPRLPLQDQWRAPPPPQDRDPFF--LGVSGEPRF-PSHLFLEQRSPPPPP-- 486
Query: 1380 PPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAET 1439
PP L SS PV +P T P PA Q + + L+ P+
Sbjct: 487 PPPTLLNSSHPVPT-----QSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGIL 541
Query: 1440 H---EAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQP 1496
H +P + P P P + P P P P PH PQ QP
Sbjct: 542 HFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQP 601
Query: 1497 APLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP 1539
P Q P P P QPP + + PP
Sbjct: 602 PP------------QHQPPHQP-----PHQPPPQHQPPPQHPP 627
Score = 42.7 bits (99), Expect = 0.004
Identities = 50/167 (29%), Positives = 61/167 (36%), Gaps = 41/167 (24%)
Query: 975 PPQPVLPPQPMLPPQPVLPPQPALPVR----PEPLQPHLPEQAAPAATPGSQILLGHPAP 1030
P QP P P PP P PPQ P+R P+PLQP LP
Sbjct: 310 PTQP--PVVPQAPPPPPPPPQQQ-PIRSLFQPQPLQPLLP-------------------- 346
Query: 1031 YAVDVAAQVPTVPVPPAAVLSPPLPEV--LLPAAPELLPQFPSSLATVSASVQSV--PTQ 1086
Q P P PP + PP E ++ P + PQ P ++ +V P Q
Sbjct: 347 ------VQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQ 400
Query: 1087 TATLLPPANP-PLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLP 1132
L P+ P P G P Q T PV S +PP LP
Sbjct: 401 VPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPN---SFSQPPRLP 444
Score = 40.8 bits (94), Expect = 0.015
Identities = 58/249 (23%), Positives = 80/249 (32%), Gaps = 38/249 (15%)
Query: 1315 ICPVAEHPAPEAPESSP------PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLL 1368
+ P A P P P+ P P PL L P P Q P L + +++
Sbjct: 315 VVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLP-VQHPHHPSPPQ--GMHMPPQLETPRMM 371
Query: 1369 SQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTS 1428
P P + P P + P PA G G P PQ
Sbjct: 372 MTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPG 431
Query: 1429 ELETS------QPLAETHEAPLAVQ---PLVVGLA-----------------PCTPAPEA 1462
+ S PL + AP Q P +G++ P P P
Sbjct: 432 PVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTL 491
Query: 1463 ASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPA--AVGAVS-LATSQLPSPPL 1519
++ + PLP P P+ + QP + P+ PA G V L SQ S
Sbjct: 492 LNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATT 551
Query: 1520 GPTVPPQPP 1528
P +PP+ P
Sbjct: 552 RPFIPPRQP 560
Score = 38.9 bits (89), Expect = 0.057
Identities = 52/194 (26%), Positives = 61/194 (31%), Gaps = 32/194 (16%)
Query: 1373 PSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQG--LTSEL 1430
P+ PP P AP P PP Q P P PQG + +L
Sbjct: 310 PTQPPVVPQAPPPPPPPP----QQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQL 365
Query: 1431 ETSQ----PLAETHEAP-----------LAVQPLVVGL--APCTPAPEAASTRDASAPRE 1473
ET + P T + P V P+ V L P P P R P
Sbjct: 366 ETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEF 425
Query: 1474 PLPPPAPEPSPHSGTPQPALGQP--APLLPAAVGAVSLATSQLPSPP-------LGPTVP 1524
P P P P+ S P+ L AP P L S P P P P
Sbjct: 426 PQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPP 485
Query: 1525 PQPPSALESDGEGP 1538
P PP+ L S P
Sbjct: 486 PPPPTLLNSSHPVP 499
Score = 33.9 bits (76), Expect = 1.8
Identities = 68/296 (22%), Positives = 91/296 (30%), Gaps = 20/296 (6%)
Query: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP--- 1373
P P P SS P+P S P +Q + Q P + L GP
Sbjct: 482 PPPPPPPPTLLNSSHPVPTQS-PLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGI 540
Query: 1374 ---SNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSEL 1430
S P A P P P P P T T P P PQ +
Sbjct: 541 LHFSQPGSATTRPFIPPRQPFLPGPGQPFLP-THTQPNLQGPLHPPLPPPHQPQPQQPQQ 599
Query: 1431 ETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRD-------ASAPREPLPPPA-PEP 1482
+ H+ P QP P P+ S P PL P + P+
Sbjct: 600 QPPPQHQPPHQPPH--QPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQF 657
Query: 1483 SPHSGTPQPALGQPAPLLPAAVGAVSLATSQ-LPSPPLGPTVPPQPPSALESDGEGPPPR 1541
PH T QP P G TSQ + P+ P P ++ + P
Sbjct: 658 RPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSH 717
Query: 1542 VGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRG-DQPRSE 1596
V + S+ S + P S A AG+ G + ++P QP+ E
Sbjct: 718 VIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEE 773
Score = 32.3 bits (72), Expect = 5.3
Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 21/124 (16%)
Query: 1410 ASGTASQAGGPGTPQGLTSELETSQP---LAETHEAPLAVQPLVVGLAPCTPAP--EAAS 1464
+S + GGP +G+ + S + + A L QP VV AP P P +
Sbjct: 272 SSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQP 331
Query: 1465 TRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVP 1524
R P +PL P P PH +P + P QL +P + T P
Sbjct: 332 IRSLFQP-QPLQPLLPVQHPHHPSPPQGMHMP---------------PQLETPRMMMTPP 375
Query: 1525 PQPP 1528
P P
Sbjct: 376 PVTP 379
Score = 31.6 bits (70), Expect = 9.1
Identities = 35/147 (23%), Positives = 57/147 (38%), Gaps = 20/147 (13%)
Query: 968 LPPQPTRPPQPVLPPQPMLPPQPVLPPQP---ALPVRPEPLQPHLPEQAAPAATPGSQIL 1024
+P T+P VLP +P +P +P P ++ RP+ +P + G
Sbjct: 919 VPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSG---- 974
Query: 1025 LGHPAPYAVDVAAQVPTVPVPPA-----AVLSPPLPEVLLPAAPELLPQFPSSLATVSAS 1079
G P+ ++++V + + P LP PE+ PQ +
Sbjct: 975 -GGDGPH---ISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGG 1030
Query: 1080 VQSVPTQTATLLPPANPPLPGGPGIAS 1106
+Q P A P A+ P+P PGI S
Sbjct: 1031 LQQPPHLPAG--PHAHSPVP--PGIKS 1053
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 119,333,348
Number of Sequences: 37866
Number of extensions: 8558374
Number of successful extensions: 165801
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 978
Number of HSP's successfully gapped in prelim test: 3165
Number of HSP's that attempted gapping in prelim test: 43303
Number of HSP's gapped (non-prelim): 58669
length of query: 2217
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2099
effective length of database: 13,779,330
effective search space: 28922813670
effective search space used: 28922813670
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.