Search of human proteins with 32307152

Search of human proteins with 32307152

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32307152 oxytocin receptor [Homo sapiens]
         (389 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32307152 oxytocin receptor [Homo sapiens]                          775   0.0  
gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]            360   1e-99
gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]            360   2e-99
gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]   264   9e-71
gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo sap...   221   9e-58
gi|46395496 G protein-coupled receptor for asthma susceptibility...   165   7e-41
gi|46391085 G protein-coupled receptor for asthma susceptibility...   165   7e-41
gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Ho...   120   2e-27
gi|4557865 somatostatin receptor 5 [Homo sapiens]                     114   1e-25
gi|4502607 cholecystokinin A receptor [Homo sapiens]                  114   1e-25
gi|28875799 cholecystokinin B receptor [Homo sapiens]                 110   3e-24
gi|149944554 somatostatin receptor 4 [Homo sapiens]                   107   2e-23
gi|222080095 orexin receptor 1 [Homo sapiens]                         106   4e-23
gi|157738685 G protein-coupled receptor 103 [Homo sapiens]            106   4e-23
gi|222080109 orexin receptor 2 [Homo sapiens]                         105   9e-23
gi|40385873 G protein-coupled receptor 150 [Homo sapiens]             100   2e-21
gi|62865887 G protein-coupled receptor 54 [Homo sapiens]               99   7e-21
gi|63477962 opioid receptor, delta 1 [Homo sapiens]                    99   9e-21
gi|4503905 galanin receptor 2 [Homo sapiens]                           95   9e-20
gi|4505513 opiate receptor-like 1 [Homo sapiens]                       95   9e-20
gi|33286424 opiate receptor-like 1 [Homo sapiens]                      95   9e-20
gi|4557857 somatostatin receptor 1 [Homo sapiens]                      94   2e-19
gi|4557861 somatostatin receptor 3 [Homo sapiens]                      93   4e-19
gi|4557859 somatostatin receptor 2 [Homo sapiens]                      91   1e-18
gi|5453666 G protein-coupled receptor 19 [Homo sapiens]                90   3e-18
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]           89   9e-18
gi|7669548 tachykinin receptor 3 [Homo sapiens]                        89   9e-18
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]      87   3e-17
gi|4885057 apelin receptor [Homo sapiens]                              86   6e-17
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]          86   7e-17

>gi|32307152 oxytocin receptor [Homo sapiens]
          Length = 389

 Score =  775 bits (2001), Expect = 0.0
 Identities = 389/389 (100%), Positives = 389/389 (100%)

Query: 1   MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV 60
           MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
Sbjct: 1   MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV 60

Query: 61  LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV 120
           LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
Sbjct: 61  LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV 120

Query: 121 VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV 180
           VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
Sbjct: 121 VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV 180

Query: 181 ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA 240
           ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
Sbjct: 181 ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA 240

Query: 241 AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW 300
           AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
Sbjct: 241 AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW 300

Query: 301 DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET 360
           DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
Sbjct: 301 DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET 360

Query: 361 SASKKSNSSSFVLSHRSSSQRSCSQPSTA 389
           SASKKSNSSSFVLSHRSSSQRSCSQPSTA
Sbjct: 361 SASKKSNSSSFVLSHRSSSQRSCSQPSTA 389


>gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]
          Length = 424

 Score =  360 bits (924), Expect = 1e-99
 Identities = 194/368 (52%), Positives = 242/368 (65%), Gaps = 17/368 (4%)

Query: 15  NASAAPPGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHS 72
           +A+  P G      A  P   R+E LA+VE+ VL  +L+LA  GN  VLL L    +K S
Sbjct: 8   DANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRS 67

Query: 73  RLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLL 132
           R+  F+ HL++ DL VA+FQVLPQLLWDIT+RF GPDLLCR VKYLQV+ MFASTY+LL 
Sbjct: 68  RMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLA 127

Query: 133 MSLDRCLAICQPLRSLRR--RTDRLAVLATWLGCLVASAPQVHIFSLREV--ADGVFDCW 188
           M+LDR LA+C PLRSL++  ++  L + A WL   + S PQV IFSLREV    GV DCW
Sbjct: 128 MTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCW 187

Query: 189 AVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAA------- 241
           A F  PWGP+AY+TW TLA++++PV +L ACY LI  +I +NL++KT A           
Sbjct: 188 ADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTW 247

Query: 242 EAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD 301
           + P  +      R   +RVSS+  IS+AKIRTVKMTF+IVLA+I CW PFF VQMWSVWD
Sbjct: 248 DRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWD 307

Query: 302 ANAPKEAS---AFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLK-GRRL 357
            NAP E S   AF I MLL +LNSCCNPWIYM F  HL    ++   CC     +  RRL
Sbjct: 308 KNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRL 367

Query: 358 GETSASKK 365
            + S S +
Sbjct: 368 SDGSLSSR 375


>gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]
          Length = 418

 Score =  360 bits (923), Expect = 2e-99
 Identities = 185/363 (50%), Positives = 243/363 (66%), Gaps = 15/363 (4%)

Query: 24  EGNRTAGPPR--RNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHL 81
           EGN   GPPR  RNE LA++E+AVL +   +A+ GN+ VLLAL  T +K SR+  F++HL
Sbjct: 37  EGN---GPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHL 93

Query: 82  SIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAI 141
           S+ADL VA FQVLPQ+ WDIT+RF GPD LCR+VK+LQV GMFAS Y+L++M+ DR +A+
Sbjct: 94  SLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAV 153

Query: 142 CQPLRSLRR--RTDRLAVLATWLGCLVASAPQVHIFSLREVAD--GVFDCWAVFIQPWGP 197
           C PL++L++  R  RL + A W+   V S PQ  +FS+ EV +     DCWA FIQPWG 
Sbjct: 154 CHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGS 213

Query: 198 KAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVAL 257
           +AY+TW+T  +++ PV++L  CYG I + IW N+R KTA+  +  A +   A   G +  
Sbjct: 214 RAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLA 273

Query: 258 ARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANA---PKEASAFIIV 314
             VSSVK IS+AKIRTVKMTF+IV A+IVCW PFF +QMWSVWD  +     E     I 
Sbjct: 274 PCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITIT 333

Query: 315 MLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLS 374
            LL SLNSCCNPWIYM F+GHL  + VQ F CC     K  +    S S++    +F  +
Sbjct: 334 ALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRR---QTFYSN 390

Query: 375 HRS 377
           +RS
Sbjct: 391 NRS 393


>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
          Length = 371

 Score =  264 bits (675), Expect = 9e-71
 Identities = 159/378 (42%), Positives = 216/378 (57%), Gaps = 37/378 (9%)

Query: 13  AANASAAP-----PGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNACVLLAL- 64
           A+  SA P     P    N +   P   R+  LAR E+A+L ++ +     N  VL AL 
Sbjct: 4   ASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALA 63

Query: 65  RTTRQKH-SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGM 123
           R  R+ H + +  F+ HL +ADL VA+FQVLPQL W  T RF GPD LCR VKYLQ+VGM
Sbjct: 64  RRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGM 123

Query: 124 FASTYLLLLMSLDRCLAICQPLRSLRRRTD---RLAVLATWLGCLVASAPQVHIFSLREV 180
           +AS+Y++L M+LDR  AIC+P+ + R  +       VL  W   L+ S PQ+ IF+ R V
Sbjct: 124 YASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNV 183

Query: 181 --ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAA 238
               GV DCWA F +PWG + Y+TWI L V++ P + +AAC  LI  +I  +L       
Sbjct: 184 EGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL------- 236

Query: 239 AAAEAPEGAAAGDGGRVALARVSSV---KLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQ 295
                  G +   GGR    R  S      +S A  +TV+MT +IV+ +++CW PFF VQ
Sbjct: 237 -----VPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQ 291

Query: 296 MWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGR 355
           +W+ WD  AP E + F+++MLLASLNSC NPWIY  F+  +  EL +  LCC+    +GR
Sbjct: 292 LWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSEL-RSLLCCA----RGR 346

Query: 356 ---RLGETSASKKSNSSS 370
               LG    S  + SSS
Sbjct: 347 TPPSLGPQDESCTTASSS 364


>gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo
           sapiens]
          Length = 309

 Score =  221 bits (563), Expect = 9e-58
 Identities = 130/312 (41%), Positives = 177/312 (56%), Gaps = 29/312 (9%)

Query: 13  AANASAAP-----PGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNACVLLAL- 64
           A+  SA P     P    N +   P   R+  LAR E+A+L ++ +     N  VL AL 
Sbjct: 4   ASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALA 63

Query: 65  RTTRQKH-SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGM 123
           R  R+ H + +  F+ HL +ADL VA+FQVLPQL W  T RF GPD LCR VKYLQ+VGM
Sbjct: 64  RRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGM 123

Query: 124 FASTYLLLLMSLDRCLAICQPLRSLRRRTD---RLAVLATWLGCLVASAPQVHIFSLREV 180
           +AS+Y++L M+LDR  AIC+P+ + R  +       VL  W   L+ S PQ+ IF+ R V
Sbjct: 124 YASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNV 183

Query: 181 --ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAA 238
               GV DCWA F +PWG + Y+TWI L V++ P + +AAC  LI  +I  +L       
Sbjct: 184 EGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL------- 236

Query: 239 AAAEAPEGAAAGDGGRVALARVSSV---KLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQ 295
                  G +   GGR    R  S      +S A  +TV+MT +IV+ +++CW PFF VQ
Sbjct: 237 -----VPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQ 291

Query: 296 MWSVWDANAPKE 307
           +W+ WD  AP E
Sbjct: 292 LWAAWDPEAPLE 303


>gi|46395496 G protein-coupled receptor for asthma susceptibility
           isoform A [Homo sapiens]
          Length = 371

 Score =  165 bits (417), Expect = 7e-41
 Identities = 96/300 (32%), Positives = 164/300 (54%), Gaps = 19/300 (6%)

Query: 42  EVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDI 101
           ++  L ++ +  + GN+ VL +    R+K SR+ FF+  L+I D    +  +L  + W  
Sbjct: 52  QLITLWVLFVFTIVGNSVVLFST-WRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRF 110

Query: 102 TFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLR-RRTDRLAVLAT 160
           T  F  PDL+CR+V+YLQVV ++ASTY+L+ +S+DR  AI  P++ L+  +  R+ ++  
Sbjct: 111 TGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA 170

Query: 161 WLGCLVASAPQVHIFSLREVADGVFDCWAVFIQP--WGPKAYITWITLAVYIVPVIVLAA 218
           W    + S P + IF  R +++G   CWA++     W P  Y+T +   VY +P+ +++ 
Sbjct: 171 WSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTP--YMTIVAFLVYFIPLTIISI 228

Query: 219 CYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTF 278
            YG++   IW  ++ KT     +   +G       R          LISKAKI+ +K + 
Sbjct: 229 MYGIVIRTIW--IKSKTYETVISNCSDGKLCSSYNR---------GLISKAKIKAIKYSI 277

Query: 279 IIVLAFIVCWTPFFFVQMWSVWD--ANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHL 336
           II+LAFI CW+P+F   +   ++   +  +   A +I+  L +LNS  NP IY +F+  +
Sbjct: 278 IIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSI 337


>gi|46391085 G protein-coupled receptor for asthma susceptibility
           isoform B [Homo sapiens]
          Length = 377

 Score =  165 bits (417), Expect = 7e-41
 Identities = 96/300 (32%), Positives = 164/300 (54%), Gaps = 19/300 (6%)

Query: 42  EVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDI 101
           ++  L ++ +  + GN+ VL +    R+K SR+ FF+  L+I D    +  +L  + W  
Sbjct: 52  QLITLWVLFVFTIVGNSVVLFST-WRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRF 110

Query: 102 TFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLR-RRTDRLAVLAT 160
           T  F  PDL+CR+V+YLQVV ++ASTY+L+ +S+DR  AI  P++ L+  +  R+ ++  
Sbjct: 111 TGDFTAPDLVCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA 170

Query: 161 WLGCLVASAPQVHIFSLREVADGVFDCWAVFIQP--WGPKAYITWITLAVYIVPVIVLAA 218
           W    + S P + IF  R +++G   CWA++     W P  Y+T +   VY +P+ +++ 
Sbjct: 171 WSLSFLFSIPTLIIFGKRTLSNGEVQCWALWPDDSYWTP--YMTIVAFLVYFIPLTIISI 228

Query: 219 CYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTF 278
            YG++   IW  ++ KT     +   +G       R          LISKAKI+ +K + 
Sbjct: 229 MYGIVIRTIW--IKSKTYETVISNCSDGKLCSSYNR---------GLISKAKIKAIKYSI 277

Query: 279 IIVLAFIVCWTPFFFVQMWSVWD--ANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHL 336
           II+LAFI CW+P+F   +   ++   +  +   A +I+  L +LNS  NP IY +F+  +
Sbjct: 278 IIILAFICCWSPYFLFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSI 337


>gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Homo
           sapiens]
          Length = 328

 Score =  120 bits (302), Expect = 2e-27
 Identities = 86/311 (27%), Positives = 150/311 (48%), Gaps = 36/311 (11%)

Query: 40  RVEVAVLCLILLLALSGNACVLLALRTTRQKH------SRLFFFMKHLSIADLVVAVFQV 93
           ++ V V   + LL+ + NA  LL L+   QK       SR+   +KHL++A+L+  +  +
Sbjct: 36  KIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVM 95

Query: 94  LPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLR-SLRRRT 152
               +W+IT ++Y  +LLC+++ YL++  M+A  ++++++SLDR LAI +PL      + 
Sbjct: 96  PLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKV 155

Query: 153 DRLAVLATWLGCLVASAPQVHIFSLREVADG-----VFD---CWAVFIQPWGPKAYITWI 204
            +  V   W+   V + PQ++IF +  +AD      VF        F Q W    Y  + 
Sbjct: 156 GQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFT 215

Query: 205 TLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVK 264
              ++I+P+ ++  C   I F + + L          + P            L    S  
Sbjct: 216 FSCLFIIPLFIMLICNAKIIFTLTRVLH---------QDPH----------ELQLNQSKN 256

Query: 265 LISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFI--IVMLLASLNS 322
            I +A+++T+KMT     +F VCWTP++ + +W  +D       S  +     L A LN 
Sbjct: 257 NIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNP 316

Query: 323 CCNPWIYMLFT 333
           C +P IY  F+
Sbjct: 317 CFDPLIYGYFS 327


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score =  114 bits (286), Expect = 1e-25
 Identities = 102/354 (28%), Positives = 162/354 (45%), Gaps = 42/354 (11%)

Query: 1   MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLA-LSGNAC 59
           ME    A+  +  A++  A  G   NRT   P  +     V V VL L++  A L GN  
Sbjct: 1   MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL 60

Query: 60  VLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRF--YGPDLLCRLVKY 117
           V+  +    +  +    ++ +L++AD++  +   LP L       F  +GP +LCRLV  
Sbjct: 61  VIYVVLRFAKMKTVTNIYILNLAVADVLYMLG--LPFLATQNAASFWPFGP-VLCRLVMT 117

Query: 118 LQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSL 177
           L  V  F S + L +MS+DR LA+  PL S R R  R+A LA+    +++    + +   
Sbjct: 118 LDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVF 177

Query: 178 REVADGVFDCWAVFIQP---WGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLK 234
            +V +G   C A + +P   WG   +I +  +  +  P++V+  CY LI  K+       
Sbjct: 178 ADVQEG-GTCNASWPEPVGLWG-AVFIIYTAVLGFFAPLLVICLCYLLIVVKV------- 228

Query: 235 TAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFV 294
                              R A  RV  V+  S+ K+   +M  ++VL F  CW PFF V
Sbjct: 229 -------------------RAAGVRVGCVRRRSERKV--TRMVLVVVLVFAGCWLPFFTV 267

Query: 295 QMWSVWDA--NAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLC 346
            + ++  A    P  A  +  V++L+  NSC NP +Y  F    F +  Q+ LC
Sbjct: 268 NIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYG-FLSDNFRQSFQKVLC 320


>gi|4502607 cholecystokinin A receptor [Homo sapiens]
          Length = 428

 Score =  114 bits (286), Expect = 1e-25
 Identities = 98/389 (25%), Positives = 168/389 (43%), Gaps = 48/389 (12%)

Query: 41  VEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVF----QVLPQ 96
           V++ +  LI LL++ GN  V+  L   ++  +    F+  L+++DL++ +F     ++P 
Sbjct: 43  VQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPN 102

Query: 97  LLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLA 156
           LL D  F       +C+   Y     +  ST+ L+ +SL+R  AIC+PL+S   +T   A
Sbjct: 103 LLKDFIFG----SAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHA 158

Query: 157 ---VLATWLGCLVASAPQVHIFSL----REVADGVFDCWAVFIQPWGPKAYITWITLAVY 209
              + ATW        P     +L    +        C  +       +++ T++ L ++
Sbjct: 159 LKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILF 218

Query: 210 IVPVIVLAACYGLISFKIWQNLRLK-------------TAAAAAAEAPEGA--------- 247
           ++P IV+   YGLIS +++Q ++ +             T ++   E  +G          
Sbjct: 219 LIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPR 278

Query: 248 -------AAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW 300
                  + G   R    R +S      AK R ++M  +IV+ F +CW P F    W  +
Sbjct: 279 KLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAY 338

Query: 301 D-ANAPKEASAFII--VMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRL 357
           D A+A +  S   I  ++LL+  +SC NP IY           +  F CC      G R 
Sbjct: 339 DTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGAR- 397

Query: 358 GETSASKKSNSSSFVLSHRSSSQRSCSQP 386
           GE    ++  ++   LS  S S  S S P
Sbjct: 398 GEVGEEEEGGTTGASLSRFSYSHMSASVP 426


>gi|28875799 cholecystokinin B receptor [Homo sapiens]
          Length = 447

 Score =  110 bits (274), Expect = 3e-24
 Identities = 101/383 (26%), Positives = 172/383 (44%), Gaps = 80/383 (20%)

Query: 16  ASAAPPGAE-------GNRTAGPPRRNEALAR-----VEVAVLCLILLLALSGNACVLLA 63
           AS   PGA        GN +  PPR   A  R     + + +  +I L+++ GN  +++ 
Sbjct: 19  ASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVV 78

Query: 64  LRTTRQKHSRLFFFMKHLSIADLVVAV----FQVLPQLLWDITFRFYGPDLLCRLVKYLQ 119
           L  +R+  +    F+  L+++DL++AV    F +LP L+    F      ++C+ V YL 
Sbjct: 79  LGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFG----TVICKAVSYLM 134

Query: 120 VVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLA---VLATWLGCLVASAPQVHIFS 176
            V +  ST  L+ ++L+R  AIC+PL++   +T   A   ++ATWL   +   P      
Sbjct: 135 GVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTV 194

Query: 177 LREVADGVFDCWAVFIQPWGPKAYI--TW---ITLAVYIVPVIVLAACYGLISFKIWQNL 231
           ++ V   V  C    +  W P A +  TW   + L ++ +P +V+A  YGLIS +++  L
Sbjct: 195 VQPVGPRVLQC----VHRW-PSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGL 249

Query: 232 RLKTAAAAAAEA-------------------PEGAAAG---DGGRVAL------------ 257
           R    + + +++                   PE  A G   DG  V L            
Sbjct: 250 RFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTAL 309

Query: 258 --------ARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD---ANAPK 306
                   +R +  KL+  AK R V+M  +IV+ F +CW P +    W  +D   A+   
Sbjct: 310 TAPGPGSGSRPTQAKLL--AKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRAL 367

Query: 307 EASAFIIVMLLASLNSCCNPWIY 329
             +    + LL+  ++C NP +Y
Sbjct: 368 SGAPISFIHLLSYASACVNPLVY 390


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score =  107 bits (266), Expect = 2e-23
 Identities = 98/362 (27%), Positives = 165/362 (45%), Gaps = 47/362 (12%)

Query: 2   EGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLC---LILLLALSGNA 58
           E  L   W + AANAS+AP  AE    AGP    +A A   VA+ C   L+ L+ L GNA
Sbjct: 12  EEGLGTAWPS-AANASSAPAEAE-EAVAGP---GDARAAGMVAIQCIYALVCLVGLVGNA 66

Query: 59  CVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYG-PDLLCRLVKY 117
            V+  +    +  +    ++ +L++AD +  +   +P +      R +    +LCR V  
Sbjct: 67  LVIFVILRYAKMKTATNIYLLNLAVADELFMLS--VPFVASSAALRHWPFGSVLCRAVLS 124

Query: 118 LQVVGMFASTYLLLLMSLDRCLAICQPLRSL---RRRTDRLAVLATWLGCLVASAPQVHI 174
           +  + MF S + L ++S+DR +A+  PLR+    R    +L  L  WL  L+ + P + I
Sbjct: 125 VDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLP-IAI 183

Query: 175 FSLREVADG--VFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLR 232
           F+    A G     C   +  P     ++ +  L  +++PV+ +  CY LI         
Sbjct: 184 FADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLI--------- 234

Query: 233 LKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFF 292
                            G    VAL      +  S+ KI   ++  ++V+ F++CW PF+
Sbjct: 235 ----------------VGKMRAVALRAGWQQRRRSEKKI--TRLVLMVVVVFVLCWMPFY 276

Query: 293 FVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYL 352
            VQ+ +++  +   +A+   + ++L+  NSC NP +Y  F    F    QR LC     L
Sbjct: 277 VVQLLNLFVTSL--DATVNHVSLILSYANSCANPILYG-FLSDNFRRFFQRVLCLRCCLL 333

Query: 353 KG 354
           +G
Sbjct: 334 EG 335


>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score =  106 bits (264), Expect = 4e-23
 Identities = 101/369 (27%), Positives = 165/369 (44%), Gaps = 34/369 (9%)

Query: 41  VEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWD 100
           V +A    + ++AL GN  V LA+       +   +F+ +LS+AD++V    +   LL D
Sbjct: 48  VLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVD 107

Query: 101 ITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPL--RSLRRRTDRLAVL 158
           IT  +     LC+++ YLQ V +  +   L  ++LDR  AIC PL  +S  RR  R ++L
Sbjct: 108 ITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRA-RGSIL 166

Query: 159 ATWLGCLVASAPQVHIFSLREVADGVFD---CWAVFIQPWG----PKAYITWITLAVYIV 211
             W   L    PQ  +     V   + +    ++V  + W     PK Y +   +  Y+ 
Sbjct: 167 GIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLA 226

Query: 212 PVIVLAACYGLISFKIWQNLRLKTAAAAAAEAP---------EGAAAGDGGRVALARVSS 262
           P+ ++A  Y  I  K+W      T +A               E   +G+    A A ++ 
Sbjct: 227 PLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAE 286

Query: 263 VKLISKAKIRTVKMTFIIVLAFIVCWTPFFFV----QMWSVWDANAPKEA--SAFIIVML 316
           VK + +A+ +T KM  +++L F +C+ P   +    +++ ++   + +EA  + F     
Sbjct: 287 VKQM-RARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHW 345

Query: 317 LASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHR 376
           L   NS  NP IY   +G    +    F CC    L G  LG    S K+ S     SH+
Sbjct: 346 LVYANSAANPIIYNFLSGKFREQFKAAFSCC----LPG--LG-PCGSLKAPSPRSSASHK 398

Query: 377 S-SSQRSCS 384
           S S Q  CS
Sbjct: 399 SLSLQSRCS 407


>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
          Length = 431

 Score =  106 bits (264), Expect = 4e-23
 Identities = 77/342 (22%), Positives = 148/342 (43%), Gaps = 33/342 (9%)

Query: 48  LILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYG 107
           LI  LAL GNA V   +  ++   +    F+  L+++DL++  F +   +L +I+  + G
Sbjct: 54  LIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLG 113

Query: 108 PDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVL---ATWLGC 164
              +C++V ++Q   +      +  ++++R   +  P +   + T+R A       WL  
Sbjct: 114 GAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVA 173

Query: 165 LVASAPQVHIFSLREVADGVFD-----CWAVFIQPWGPKAYITWITLAVYIVPVIVLAAC 219
           ++  +P  H+  L    D +++     C   +  P   K Y T+I + ++++P++V+   
Sbjct: 174 VIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLIL 233

Query: 220 YGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFI 279
           Y  I +++W   R+                GDG  +       +  I++ K R V M   
Sbjct: 234 YSKIGYELWIKKRV----------------GDGSVLRTIHGKEMSKIARKKKRAVIMMVT 277

Query: 280 IVLAFIVCWTPFFFVQMWSVWDANAPKE------ASAFIIVMLLASLNSCCNPWIYMLFT 333
           +V  F VCW PF  V M   + +N  KE         F IV ++   NS CNP +Y    
Sbjct: 278 VVALFAVCWAPFHVVHMMIEY-SNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMN 336

Query: 334 GHLFHELVQRFLCC--SASYLKGRRLGETSASKKSNSSSFVL 373
            +    ++     C  + ++   +R G +  +     + F L
Sbjct: 337 ENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAKFSL 378


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score =  105 bits (261), Expect = 9e-23
 Identities = 94/379 (24%), Positives = 165/379 (43%), Gaps = 34/379 (8%)

Query: 41  VEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWD 100
           V +A   ++ ++AL GN  V +A+       +   +F+ +LS+AD++V +  +   L+ D
Sbjct: 56  VLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVD 115

Query: 101 ITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPL--RSLRRRTDRLAVL 158
           IT  ++    LC+++ YLQ V +  S   L  ++LDR  AIC PL  +S  +R  R +++
Sbjct: 116 ITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRA-RNSIV 174

Query: 159 ATWLGCLVASAPQVHIFSLREVADGVFDCWAVFI---QPWG----PKAYITWITLAVYIV 211
             W+   +   PQ  +     V  G+ +   +F    + WG    PK Y     L  Y+ 
Sbjct: 175 IIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMA 234

Query: 212 PVIVLAACYGLISFKIW--------QNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSV 263
           P+ ++   Y  I  K+W          ++ K         P G       R++ A  + +
Sbjct: 235 PLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMS-AVAAEI 293

Query: 264 KLISKAKIRTVKMTFIIVLAFIVCWTPFFFV----QMWSVWDANAPKEA--SAFIIVMLL 317
           K I +A+ +T +M  I++L F +C+ P   +    +++ ++     +E   + F     L
Sbjct: 294 KQI-RARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWL 352

Query: 318 ASLNSCCNPWIYMLFTGHLFHELVQRFLCCSAS--------YLKGRRLGETSASKKSNSS 369
              NS  NP IY   +G    E    F CC             +GR   E+  S  +  S
Sbjct: 353 VYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQIS 412

Query: 370 SFVLSHRSSSQRSCSQPST 388
           +F    + S Q   +  ST
Sbjct: 413 NFDNISKLSEQVVLTSIST 431


>gi|40385873 G protein-coupled receptor 150 [Homo sapiens]
          Length = 434

 Score =  100 bits (249), Expect = 2e-21
 Identities = 105/368 (28%), Positives = 170/368 (46%), Gaps = 66/368 (17%)

Query: 24  EGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLAL-----RTTRQKHSRLFFFM 78
           +G   +GPP R     RV +  L +IL++A++GN  VL  L          K  ++ F +
Sbjct: 32  QGAPASGPPSR-----RVRLVFLGVILVVAVAGNTTVLCRLCGGGGPWAGPKRRKMDFLL 86

Query: 79  KHLSIADLVVAVFQVLPQLLWDITF--RFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLD 136
             L++ADL       L QL W++    R    DL CR ++ LQ  G  AS +L++L++L+
Sbjct: 87  VQLALADLYACGGTALSQLAWELLGEPRAATGDLACRFLQLLQASGRGASAHLVVLIALE 146

Query: 137 RCLAICQPL-RSLRRRTDRLAVLATWLGCLVASAPQVHIF---------------SLREV 180
           R  A+  P  R L  R   LA L  WL  L+ + P   +                SL+  
Sbjct: 147 RRRAVRLPHGRPLPARA--LAALG-WLLALLLALPPAFVVRGDSPSPLPPPPPPTSLQPG 203

Query: 181 AD-------GVFDCWAVF--IQPWGPKAYITWITLAVYIVPVIVLA-ACYGLISFKIWQN 230
           A        G   C  +F  +  W  + Y  +  +A ++ PV VL  AC  L+S  +W  
Sbjct: 204 APPAARAWPGERRCHGIFAPLPRWHLQVYAFYEAVAGFVAPVTVLGVACGHLLS--VWWR 261

Query: 231 LRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTP 290
            R +  AAAA   P  A+ G        R  +   + +AK++++KM+ ++ L F+ C  P
Sbjct: 262 HRPQAPAAAA---PWSASPG--------RAPAPSALPRAKVQSLKMSLLLALLFVGCELP 310

Query: 291 FFFVQMWSVWDANAPKE-----ASAFIIVMLLASLNSCCNPWIYMLFTG---HLFHELVQ 342
           +F  ++ + W +    +      SA + V+ +A  NS  NP++Y+ F      L  +L +
Sbjct: 311 YFAARLAAAWSSGPAGDWEGEGLSAALRVVAMA--NSALNPFVYLFFQAGDCRLRRQLRK 368

Query: 343 RF--LCCS 348
           R   LCC+
Sbjct: 369 RLGSLCCA 376


>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
          Length = 398

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 95/354 (26%), Positives = 159/354 (44%), Gaps = 35/354 (9%)

Query: 7   ANWSAEAANASAAPPGAEGNRTAGP-PRRNEALARVEVAVLCLILLLALSGNACVLLALR 65
           A+W A A NAS  P G   N + GP P      A +       ++LL L GN+ V+  + 
Sbjct: 11  ASWGAPA-NASGCP-GCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVIC 68

Query: 66  TTRQKHSRLFFFMKHLSIADLVVAVFQV-LPQLLWDITFRFYGPDLLCRLVKYLQVVGMF 124
             +   +   F++ +L+  D+   +  V    LL+ +     G D +C+ V Y+Q V + 
Sbjct: 69  RHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLG-DFMCKFVNYIQQVSVQ 127

Query: 125 ASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAV---LATWLGCLVASAPQVHIFSLREVA 181
           A+   L  MS+DR      PLR+L RRT RLA+   L+ W+G    SAP   + +L  ++
Sbjct: 128 ATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAP---VLALHRLS 184

Query: 182 DGV-FDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA 240
            G    C   F      +A+  +  LA+Y++P++   ACY  +   +    R+    A A
Sbjct: 185 PGPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLG---RVAVRPAPA 241

Query: 241 AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPF-FFVQMWSV 299
             A +G    +      A+VS             ++   +VL F  CW P   F+ + ++
Sbjct: 242 DSALQGQVLAERAGAVRAKVS-------------RLVAAVVLLFAACWGPIQLFLVLQAL 288

Query: 300 WDANA--PKEASAFII---VMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCS 348
             A +  P+  +A+ +      ++  NS  NP +Y  F G  F +  +R   C+
Sbjct: 289 GPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLY-AFLGSHFRQAFRRVCPCA 341


>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
          Length = 372

 Score = 98.6 bits (244), Expect = 9e-21
 Identities = 89/341 (26%), Positives = 146/341 (42%), Gaps = 64/341 (18%)

Query: 14  ANASAAPPGA---EGNRTAGPPRRNEA----LARVEVAVLCLILLLALSGNACVLLALRT 66
           ANAS A P A    G   +GPP    A    LA    A+   +  + L GN  V+  +  
Sbjct: 17  ANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVR 76

Query: 67  TRQKHSRLFFFMKHLSIADLVVAV---FQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGM 123
             +  +    ++ +L++AD +      FQ    L+    F     +LLC+ V  +    M
Sbjct: 77  YTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFG----ELLCKAVLSIDYYNM 132

Query: 124 FASTYLLLLMSLDRCLAICQPLRSLRRRTD---RLAVLATWLGCLVASAPQVHIFSLREV 180
           F S + L +MS+DR +A+C P+++L  RT    +L  +  W+       P + + ++   
Sbjct: 133 FTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVP-IMVMAVTRP 191

Query: 181 ADGVFDCWAVFIQP---WGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAA 237
            DG   C   F  P   W     I  + L  ++VP++++  CYGL+              
Sbjct: 192 RDGAVVCMLQFPSPSWYWDTVTKIC-VFLFAFVVPILIITVCYGLM-------------- 236

Query: 238 AAAAEAPEGAAAGDGGRVALARVSSVKLISKAK------IRTVKMTFIIVLAFIVCWTPF 291
                              L R+ SV+L+S +K       R  +M  ++V AF+VCW P 
Sbjct: 237 -------------------LLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI 277

Query: 292 -FFVQMWSVWDANA--PKEASAFIIVMLLASLNSCCNPWIY 329
             FV +W++ D +   P   +A  + + L   NS  NP +Y
Sbjct: 278 HIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLY 318


>gi|4503905 galanin receptor 2 [Homo sapiens]
          Length = 387

 Score = 95.1 bits (235), Expect = 9e-20
 Identities = 102/376 (27%), Positives = 155/376 (41%), Gaps = 38/376 (10%)

Query: 21  PGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKH 80
           PGA     AG        A +   +  LI L+   GN  VL  L    Q  S    F+ +
Sbjct: 7   PGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILN 66

Query: 81  LSIADLVVAVFQVLPQL-LWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCL 139
           L +ADL   +  V  Q  ++ +    +G  LLC+ V +L  + M AS++ L  +SLDR L
Sbjct: 67  LGVADLCFILCCVPFQATIYTLDGWVFG-SLLCKAVHFLIFLTMHASSFTLAAVSLDRYL 125

Query: 140 AICQPLRSLRRRTDRLAVLA---TWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWG 196
           AI  PL S   RT R A+ A    W   L+ S P +  +   ++A+ +  C   +  P  
Sbjct: 126 AIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLAN-LTVCHPAWSAPRR 184

Query: 197 PKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVA 256
               I     + Y++PV+VL   Y      +W+             A +  AAG G R  
Sbjct: 185 RAMDICTFVFS-YLLPVLVLGLTYARTLRYLWR-------------AVDPVAAGSGAR-- 228

Query: 257 LARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAF---II 313
                      +AK +  +M  I+   F +CW P   + +  VW    P   + +   I+
Sbjct: 229 -----------RAKRKVTRMILIVAALFCLCWMPHHAL-ILCVWFGQFPLTRATYALRIL 276

Query: 314 VMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVL 373
             L++  NSC NP +Y L + H F +  +           GR  G   A+ +   S  VL
Sbjct: 277 SHLVSYANSCVNPIVYALVSKH-FRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVL 335

Query: 374 SHRSSSQRSCSQPSTA 389
              SS     S+ + A
Sbjct: 336 ERESSDLLHMSEAAGA 351


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 95.1 bits (235), Expect = 9e-20
 Identities = 103/369 (27%), Positives = 158/369 (42%), Gaps = 72/369 (19%)

Query: 5   LAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLA-----LSGNAC 59
           L  N S  + N S  PP    N + G      A   + + V  + L LA     L GN  
Sbjct: 18  LQGNLSLLSPNHSLLPPHLLLNASHG------AFLPLGLKVTIVGLYLAVCVGGLLGNCL 71

Query: 60  VL-LALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYG-PDLLCRLVKY 117
           V+ + LR T+ K +   +   +L++AD +V +   LP    DI   F+   + LC+ V  
Sbjct: 72  VMYVILRHTKMKTATNIYIF-NLALADTLVLL--TLPFQGTDILLGFWPFGNALCKTVIA 128

Query: 118 LQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAV---LATWLGCLVASAPQVHI 174
           +    MF ST+ L  MS+DR +AIC P+R+L  RT   A    +A W    V   P V I
Sbjct: 129 IDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVP-VAI 187

Query: 175 FSLREVADGVFDCWAVFIQP---WGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNL 231
               +V D   +C      P   WGP  +   I L  +IVPV+V++ CY L+        
Sbjct: 188 MGSAQVEDEEIECLVEIPTPQDYWGP-VFAICIFLFSFIVPVLVISVCYSLM-------- 238

Query: 232 RLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAK------IRTVKMTFIIVLAFI 285
                                    + R+  V+L+S ++       R  ++  ++V  F+
Sbjct: 239 -------------------------IRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFV 273

Query: 286 VCWTPFFFVQMWSVWDANAPKEASAFIIVML-----LASLNSCCNPWIYMLFTGHLFHEL 340
            CWTP   VQ++ +      + +S   + +L     L  +NSC NP +Y  F    F   
Sbjct: 274 GCWTP---VQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILY-AFLDENFKAC 329

Query: 341 VQRFLCCSA 349
            ++F C SA
Sbjct: 330 FRKFCCASA 338


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 95.1 bits (235), Expect = 9e-20
 Identities = 103/369 (27%), Positives = 158/369 (42%), Gaps = 72/369 (19%)

Query: 5   LAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLA-----LSGNAC 59
           L  N S  + N S  PP    N + G      A   + + V  + L LA     L GN  
Sbjct: 18  LQGNLSLLSPNHSLLPPHLLLNASHG------AFLPLGLKVTIVGLYLAVCVGGLLGNCL 71

Query: 60  VL-LALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYG-PDLLCRLVKY 117
           V+ + LR T+ K +   +   +L++AD +V +   LP    DI   F+   + LC+ V  
Sbjct: 72  VMYVILRHTKMKTATNIYIF-NLALADTLVLL--TLPFQGTDILLGFWPFGNALCKTVIA 128

Query: 118 LQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAV---LATWLGCLVASAPQVHI 174
           +    MF ST+ L  MS+DR +AIC P+R+L  RT   A    +A W    V   P V I
Sbjct: 129 IDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVP-VAI 187

Query: 175 FSLREVADGVFDCWAVFIQP---WGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNL 231
               +V D   +C      P   WGP  +   I L  +IVPV+V++ CY L+        
Sbjct: 188 MGSAQVEDEEIECLVEIPTPQDYWGP-VFAICIFLFSFIVPVLVISVCYSLM-------- 238

Query: 232 RLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAK------IRTVKMTFIIVLAFI 285
                                    + R+  V+L+S ++       R  ++  ++V  F+
Sbjct: 239 -------------------------IRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFV 273

Query: 286 VCWTPFFFVQMWSVWDANAPKEASAFIIVML-----LASLNSCCNPWIYMLFTGHLFHEL 340
            CWTP   VQ++ +      + +S   + +L     L  +NSC NP +Y  F    F   
Sbjct: 274 GCWTP---VQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILY-AFLDENFKAC 329

Query: 341 VQRFLCCSA 349
            ++F C SA
Sbjct: 330 FRKFCCASA 338


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 93/355 (26%), Positives = 155/355 (43%), Gaps = 44/355 (12%)

Query: 2   EGALAANWSAEAANASAAPP-GAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV 60
           EG  +    A AA+    P   A  N T    + +  L     +V+CL+    L GN+ V
Sbjct: 23  EGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLV---GLCGNSMV 79

Query: 61  LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYG-PDLLCRLVKYLQ 119
           +  +    +  +    ++ +L+IAD ++ +   +P L+     R +    LLCRLV  + 
Sbjct: 80  IYVILRYAKMKTATNIYILNLAIADELLMLS--VPFLVTSTLLRHWPFGALLCRLVLSVD 137

Query: 120 VVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAV---LATWLGCLVASAPQVHIFS 176
            V MF S Y L ++S+DR +A+  P+++ R R   +A    L  W+  L+   P V    
Sbjct: 138 AVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSR 197

Query: 177 LREVADGVFDCWAVFIQP---WGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRL 233
               +DG   C  +  +P   W    ++ +  L  +++PV  +  CY LI  K+      
Sbjct: 198 TAANSDGTVACNMLMPEPAQRW-LVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRM---- 252

Query: 234 KTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFF 293
                                VAL      +  S+ KI    M  ++V+ F++CW PF+ 
Sbjct: 253 ---------------------VALKAGWQQRKRSERKITL--MVMMVVMVFVICWMPFYV 289

Query: 294 VQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCS 348
           VQ+ +V+      +A+   + ++L   NSC NP +Y  F    F    QR LC S
Sbjct: 290 VQLVNVFAEQ--DDATVSQLSVILGYANSCANPILYG-FLSDNFKRSFQRILCLS 341


>gi|4557861 somatostatin receptor 3 [Homo sapiens]
          Length = 418

 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 96/348 (27%), Positives = 160/348 (45%), Gaps = 48/348 (13%)

Query: 10  SAEAANASAA-PPGAE-GNRTAGPPRRNEALARVEVAVLCLIL-LLALSGNACVLLALRT 66
           ++E  NAS+A PP A  GN +AGP     A++ V + ++ L++ ++ L GN+ V+  +  
Sbjct: 12  TSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLR 71

Query: 67  TRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYG-PDLLCRLVKYLQVVGMFA 125
                S    ++ +L++AD +  +   LP L       ++    L+CRLV  +  +  F 
Sbjct: 72  HTASPSVTNVYILNLALADELFMLG--LPFLAAQNALSYWPFGSLMCRLVMAVDGINQFT 129

Query: 126 STYLLLLMSLDRCLAICQPLRSLRRRT---DRLAVLATWLGCLVASAPQVHIFSLREVAD 182
           S + L +MS+DR LA+  P RS R RT    R    A W+   V   P V +FS   V  
Sbjct: 130 SIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVV-VFS--GVPR 186

Query: 183 GVFDCWAVFIQP---WGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAA 239
           G+  C   + +P   W    +I +     +  P++V+  CY LI  K+        +A  
Sbjct: 187 GMSTCHMQWPEPAAAW-RAGFIIYTAALGFFGPLLVICLCYLLIVVKV-------RSAGR 238

Query: 240 AAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSV 299
              AP                 S +   +++ R  +M   +V  F++CW PF+ + + +V
Sbjct: 239 RVWAP-----------------SCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNV 281

Query: 300 WDANAPKEASAFIIVMLLASL---NSCCNPWIYMLFTGHLFHELVQRF 344
                P+E + F +  L+ +L   NSC NP +Y    G L +   Q F
Sbjct: 282 -VCPLPEEPAFFGLYFLVVALPYANSCANPILY----GFLSYRFKQGF 324


>gi|4557859 somatostatin receptor 2 [Homo sapiens]
          Length = 369

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 87/344 (25%), Positives = 145/344 (42%), Gaps = 45/344 (13%)

Query: 48  LILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYG 107
           ++ ++ L GN  V+  +    +  +    ++ +L+IAD +  +   LP L   +    + 
Sbjct: 52  VVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLG--LPFLAMQVALVHWP 109

Query: 108 -PDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSL---RRRTDRLAVLATWLG 163
               +CR+V  +  +  F S + L +MS+DR LA+  P++S    R RT ++  +A W  
Sbjct: 110 FGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGV 169

Query: 164 CLVASAPQVHIFSLREVADGVFDC---WAVFIQPWGPKAYITWITLAVYIVPVIVLAACY 220
            L+   P +    LR    G   C   W      W    +I +  +  ++VP+ ++  CY
Sbjct: 170 SLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAW-YTGFIIYTFILGFLVPLTIICLCY 228

Query: 221 GLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFII 280
             I  K+                  G   G   R             K++ +  +M  I+
Sbjct: 229 LFIIIKV---------------KSSGIRVGSSKR------------KKSEKKVTRMVSIV 261

Query: 281 VLAFIVCWTPFFFVQMWSVWDANAPKEA--SAFIIVMLLASLNSCCNPWIYMLFTGHLFH 338
           V  FI CW PF+   + SV  A +P  A    F  V++L   NSC NP +Y  F    F 
Sbjct: 262 VAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILY-AFLSDNFK 320

Query: 339 ELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRS 382
           +  Q  LC     + G   GE S SK+  S    L+  + +QR+
Sbjct: 321 KSFQNVLCLVK--VSGTDDGERSDSKQDKSR---LNETTETQRT 359


>gi|5453666 G protein-coupled receptor 19 [Homo sapiens]
          Length = 415

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 69/343 (20%), Positives = 145/343 (42%), Gaps = 31/343 (9%)

Query: 48  LILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYG 107
           ++ L ++ GN+ V L +  +R+  S   +F+  ++ ADL+++V      LL   T R+  
Sbjct: 74  ILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTL 133

Query: 108 PDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLR-SLRRRTDRLAVLATWLGCLV 166
               C++V+Y Q +      Y+LL + +DR   I  PL   + R   +  + A+W+    
Sbjct: 134 GSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWIFDAG 193

Query: 167 ASAPQVHIFSLREVADGVFDCWAVFIQP--WGPKAYITWITLAVYIVPVIVLAACYGLIS 224
              P +  +         +D    +  P  W   AY     L  +++P +++   Y  + 
Sbjct: 194 FVTPVLFFYGSN------WDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQKVI 247

Query: 225 FKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAF 284
             IW+                    G  GR       ++ ++ + K++T+KM  I+ L F
Sbjct: 248 KYIWR-------------------IGTDGRTVRR---TMNIVPRTKVKTIKMFLILNLLF 285

Query: 285 IVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRF 344
           ++ W PF   Q+W   + +  K +  F  +  ++  +S   P +Y ++  +    + + F
Sbjct: 286 LLSWLPFHVAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETF 345

Query: 345 LCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPS 387
              S    +      T++S+ +  +   +S   S  ++ ++ S
Sbjct: 346 CMSSMKCYRSNAYTITTSSRMAKKNYVGISEIPSMAKTITKDS 388


>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
          Length = 407

 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 71/311 (22%), Positives = 131/311 (42%), Gaps = 31/311 (9%)

Query: 44  AVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITF 103
           A   +I++ ++ GN  V+  +   ++  +   +F+ +L+ A+  +A F  +    + +  
Sbjct: 37  AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96

Query: 104 RFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLR-SLRRRTDRLAVLATWL 162
            +Y     C+   +  +  +FAS Y +  ++ DR +AI  PL+  L     ++ +   W+
Sbjct: 97  EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWV 156

Query: 163 GCLVASAPQVHIFSLREVADGVFDC---WAVFIQPWGPKAYITWITLAVYIVPVIVLAAC 219
             L+ + PQ + +S  E       C   W         K Y   +T+ +Y +P++V+   
Sbjct: 157 LALLLAFPQGY-YSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYA 215

Query: 220 YGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFI 279
           Y ++   +W           A+E P     GD       +VS       AK + VKM  +
Sbjct: 216 YTVVGITLW-----------ASEIP-----GDSSDRYHEQVS-------AKRKVVKMMIV 252

Query: 280 IVLAFIVCWTPF--FFVQMWSVWDANAPK-EASAFIIVMLLASLNSCCNPWIYMLFTGHL 336
           +V  F +CW PF  FF+  +   D    K     ++ +M LA  ++  NP IY       
Sbjct: 253 VVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRF 312

Query: 337 FHELVQRFLCC 347
                  F CC
Sbjct: 313 RLGFKHAFRCC 323


>gi|7669548 tachykinin receptor 3 [Homo sapiens]
          Length = 465

 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 66/290 (22%), Positives = 129/290 (44%), Gaps = 35/290 (12%)

Query: 48  LILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYG 107
           +++ +A+ GN  V+  +   ++  +   +F+ +L+ +D  +A F  L   ++ +   +Y 
Sbjct: 94  VVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYF 153

Query: 108 PDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLR-SLRRRTDRLAVLATWLGCLV 166
               CR   +  +  +FAS Y +  +++DR +AI  PL+  L     ++ + + W+   +
Sbjct: 154 GANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFL 213

Query: 167 ASAPQVHIFSLREVADGVFDCWAVFIQ-PWGPKAYITW---ITLAVYIVPVIVLAACYGL 222
            + PQ  ++S  +V  G   C   F+Q P GPK + T+   + + VY  P++++   Y +
Sbjct: 214 LAFPQC-LYSKTKVMPGRTLC---FVQWPEGPKQHFTYHIIVIILVYCFPLLIMGITYTI 269

Query: 223 ISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVL 282
           +   +W                       GG +            KAK + VKM  I+V+
Sbjct: 270 VGITLW-----------------------GGEIPGDTCDKYHEQLKAKRKVVKMMIIVVM 306

Query: 283 AFIVCWTPF--FFVQMWSVWDANAPKE-ASAFIIVMLLASLNSCCNPWIY 329
            F +CW P+  +F+        N  K     ++    LA  ++  NP IY
Sbjct: 307 TFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIY 356


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 81/361 (22%), Positives = 152/361 (42%), Gaps = 55/361 (15%)

Query: 43  VAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAV---FQVLPQLLW 99
           +A+  ++ ++ L GN  V+  +    +  +    ++ +L++AD +      FQ +  L+ 
Sbjct: 74  MALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMG 133

Query: 100 DITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLA 159
              F      +LC++V  +    MF S + L  MS+DR +A+C P+++L  RT R A + 
Sbjct: 134 TWPFG----TILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKII 189

Query: 160 TWLGCLVASA--PQVHIFSLREVADGVFDCWAVFIQP---WGPKAYITWITLAVYIVPVI 214
                +++SA    V   +  +   G  DC   F  P   W     I  + +  +I+PV+
Sbjct: 190 NVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKIC-VFIFAFIMPVL 248

Query: 215 VLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAK---- 270
           ++  CYGL+                                 + R+ SV+++S +K    
Sbjct: 249 IITVCYGLM---------------------------------ILRLKSVRMLSGSKEKDR 275

Query: 271 --IRTVKMTFIIVLAFIVCWTP--FFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNP 326
              R  +M  ++V  FIVCWTP   + +    V       +  ++   + L   NSC NP
Sbjct: 276 NLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNP 335

Query: 327 WIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQP 386
            +Y  F    F    + F   ++S ++ +       + + + S+     R++ QR   Q 
Sbjct: 336 VLY-AFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQRERRQK 394

Query: 387 S 387
           S
Sbjct: 395 S 395


>gi|4885057 apelin receptor [Homo sapiens]
          Length = 380

 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 90/352 (25%), Positives = 147/352 (41%), Gaps = 59/352 (16%)

Query: 44  AVLCLILLLALSGNACVLLAL-RTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLW-DI 101
           A+  L+ LL  +GN  VL  + R++R+K      F+  L++ADL   V   LP  LW   
Sbjct: 33  AIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVV--TLP--LWATY 88

Query: 102 TFRFYG---PDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVL 158
           T+R Y        C+L  YL  V M+AS + L  +S DR LAI +P+ + R R      +
Sbjct: 89  TYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAV 148

Query: 159 ATWLGCLVASAPQVHIFSLREVAD----GVFDCWAVFIQPWGPKAYITW-------ITLA 207
           AT +  ++A+   + +  LR   D        C+  +       +   W        T  
Sbjct: 149 ATAVLWVLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTV 208

Query: 208 VYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLIS 267
            ++VP  ++  CY  I+  I  + R         E  EG                     
Sbjct: 209 GFVVPFTIMLTCYFFIAQTIAGHFR--------KERIEGL-------------------- 240

Query: 268 KAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDA--NAPKEASAFIIVML-----LASL 320
           + + R + +  ++V+ F +CW P+  V+   +  +  + P +   F++ +      ++ +
Sbjct: 241 RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV 300

Query: 321 NSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKG---RRLGETSASKKSNSS 369
           NSC NP++Y  F    F +     LCC  S   G      GE SAS  S  S
Sbjct: 301 NSCLNPFLYAFFDPR-FRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHS 351


>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
          Length = 311

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 68/293 (23%), Positives = 128/293 (43%), Gaps = 31/293 (10%)

Query: 44  AVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITF 103
           A   +I++ ++ GN  V+  +   ++  +   +F+ +L+ A+  +A F  +    + +  
Sbjct: 37  AAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHN 96

Query: 104 RFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLR-SLRRRTDRLAVLATWL 162
            +Y     C+   +  +  +FAS Y +  ++ DR +AI  PL+  L     ++ +   W+
Sbjct: 97  EWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWV 156

Query: 163 GCLVASAPQVHIFSLREVADGVFDC---WAVFIQPWGPKAYITWITLAVYIVPVIVLAAC 219
             L+ + PQ + +S  E       C   W         K Y   +T+ +Y +P++V+   
Sbjct: 157 LALLLAFPQGY-YSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYA 215

Query: 220 YGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFI 279
           Y ++   +W           A+E P     GD       +VS       AK + VKM  +
Sbjct: 216 YTVVGITLW-----------ASEIP-----GDSSDRYHEQVS-------AKRKVVKMMIV 252

Query: 280 IVLAFIVCWTPF--FFVQMWSVWDANAPK-EASAFIIVMLLASLNSCCNPWIY 329
           +V  F +CW PF  FF+  +   D    K     ++ +M LA  ++  NP IY
Sbjct: 253 VVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIY 305


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.136    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,767,911
Number of Sequences: 37866
Number of extensions: 530523
Number of successful extensions: 4586
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 491
Number of HSP's successfully gapped in prelim test: 271
Number of HSP's that attempted gapping in prelim test: 3084
Number of HSP's gapped (non-prelim): 980
length of query: 389
length of database: 18,247,518
effective HSP length: 104
effective length of query: 285
effective length of database: 14,309,454
effective search space: 4078194390
effective search space used: 4078194390
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.