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Search of human proteins with 32130516
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32130516 serologically defined colon cancer antigen 1 [Homo
sapiens]
(1076 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32130516 serologically defined colon cancer antigen 1 [Homo s... 2136 0.0
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 61 6e-09
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 61 6e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 57 9e-08
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 57 1e-07
gi|104526627 triadin [Homo sapiens] 56 2e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 55 4e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 55 4e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 6e-07
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 54 8e-07
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 54 8e-07
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap... 54 8e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 1e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 53 1e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 53 1e-06
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 53 2e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 53 2e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 53 2e-06
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 53 2e-06
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 53 2e-06
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 52 2e-06
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 52 2e-06
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 52 3e-06
gi|110611184 chromodomain helicase DNA binding protein 2 isoform... 52 3e-06
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 51 5e-06
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 51 5e-06
gi|24415404 MDN1, midasin homolog [Homo sapiens] 51 5e-06
gi|157738619 smoothelin-like 1 [Homo sapiens] 51 7e-06
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 50 9e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 50 9e-06
>gi|32130516 serologically defined colon cancer antigen 1 [Homo
sapiens]
Length = 1076
Score = 2136 bits (5534), Expect = 0.0
Identities = 1076/1076 (100%), Positives = 1076/1076 (100%)
Query: 1 MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHT 60
MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHT
Sbjct: 1 MKSRFSTIDLRAVLAELNASLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHT 60
Query: 61 TEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRG 120
TEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRG
Sbjct: 61 TEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRG 120
Query: 121 NIVLTDYEYVILNILRFRTDEADDVKFAVRERYPLDHARAAEPLLTLERLTEIVASAPKG 180
NIVLTDYEYVILNILRFRTDEADDVKFAVRERYPLDHARAAEPLLTLERLTEIVASAPKG
Sbjct: 121 NIVLTDYEYVILNILRFRTDEADDVKFAVRERYPLDHARAAEPLLTLERLTEIVASAPKG 180
Query: 181 ELLKRVLNPLLPYGPALIEHCLLENGFSGNVKVDEKLETKDIEKVLVSLQKAEDYMKTTS 240
ELLKRVLNPLLPYGPALIEHCLLENGFSGNVKVDEKLETKDIEKVLVSLQKAEDYMKTTS
Sbjct: 181 ELLKRVLNPLLPYGPALIEHCLLENGFSGNVKVDEKLETKDIEKVLVSLQKAEDYMKTTS 240
Query: 241 NFSGKGYIIQKREIKPCLEADKPVEDILTYEEFHPFLFSQHSQCPYIEFESFDKAVDEFY 300
NFSGKGYIIQKREIKPCLEADKPVEDILTYEEFHPFLFSQHSQCPYIEFESFDKAVDEFY
Sbjct: 241 NFSGKGYIIQKREIKPCLEADKPVEDILTYEEFHPFLFSQHSQCPYIEFESFDKAVDEFY 300
Query: 301 SKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDR 360
SKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDR
Sbjct: 301 SKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDR 360
Query: 361 AIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEE 420
AIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEE
Sbjct: 361 AIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEE 420
Query: 421 DDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHK 480
DDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHK
Sbjct: 421 DDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHK 480
Query: 481 RYAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYL 540
RYAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYL
Sbjct: 481 RYAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYL 540
Query: 541 IIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCY 600
IIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCY
Sbjct: 541 IIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCY 600
Query: 601 SAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVD 660
SAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVD
Sbjct: 601 SAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVD 660
Query: 661 ESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL 720
ESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL
Sbjct: 661 ESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL 720
Query: 721 MTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDT 780
MTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDT
Sbjct: 721 MTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDT 780
Query: 781 TIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALE 840
TIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALE
Sbjct: 781 TIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALE 840
Query: 841 GKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGS 900
GKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGS
Sbjct: 841 GKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGS 900
Query: 901 AGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDD 960
AGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDD
Sbjct: 901 AGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDD 960
Query: 961 PHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQ 1020
PHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQ
Sbjct: 961 PHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQ 1020
Query: 1021 KKGKAAKTALNSFMHSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLNVKRK 1076
KKGKAAKTALNSFMHSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLNVKRK
Sbjct: 1021 KKGKAAKTALNSFMHSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLNVKRK 1076
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 60.8 bits (146), Expect = 6e-09
Identities = 68/286 (23%), Positives = 118/286 (41%), Gaps = 46/286 (16%)
Query: 677 DEDMETLA--SCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSG 734
DED +A + T+ S+ ME D SSD + +TP L V + S
Sbjct: 120 DEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPA---LKMSVSKRARKASSD 176
Query: 735 RDELNEELIQEESSEDEGEYEEVRKDQD---------------SVGEMKDEGEETLNYPD 779
D+ + +EE+SE E E+ DQD +G K + + + D
Sbjct: 177 LDQASVSPSEEENSESSSESEKT-SDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSD 235
Query: 780 TTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKE---RREMKKKKLPSDSG-- 834
+ D +P + +A +S+SS S S S +S K+ R+ +K LP G
Sbjct: 236 SKADSDGAKP----EPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRK 291
Query: 835 ------DLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE 888
+ D ++ + ++ ++ +R Q+ ++++++E+ K++ E
Sbjct: 292 PKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKE 351
Query: 889 EDRELIMKLLGSAGSNKEEKGKKGKKG---KTKDEPVKKQPQKPRG 931
RE A + E+G G G + DEPVKK+ +K RG
Sbjct: 352 RRRE-------RADRGEAERGSGGSSGDELREDDEPVKKRGRKGRG 390
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 60.8 bits (146), Expect = 6e-09
Identities = 68/286 (23%), Positives = 118/286 (41%), Gaps = 46/286 (16%)
Query: 677 DEDMETLA--SCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSG 734
DED +A + T+ S+ ME D SSD + +TP L V + S
Sbjct: 120 DEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPA---LKMSVSKRARKASSD 176
Query: 735 RDELNEELIQEESSEDEGEYEEVRKDQD---------------SVGEMKDEGEETLNYPD 779
D+ + +EE+SE E E+ DQD +G K + + + D
Sbjct: 177 LDQASVSPSEEENSESSSESEKT-SDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSD 235
Query: 780 TTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKE---RREMKKKKLPSDSG-- 834
+ D +P + +A +S+SS S S S +S K+ R+ +K LP G
Sbjct: 236 SKADSDGAKP----EPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRK 291
Query: 835 ------DLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE 888
+ D ++ + ++ ++ +R Q+ ++++++E+ K++ E
Sbjct: 292 PKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKE 351
Query: 889 EDRELIMKLLGSAGSNKEEKGKKGKKG---KTKDEPVKKQPQKPRG 931
RE A + E+G G G + DEPVKK+ +K RG
Sbjct: 352 RRRE-------RADRGEAERGSGGSSGDELREDDEPVKKRGRKGRG 390
Score = 38.1 bits (87), Expect = 0.045
Identities = 76/363 (20%), Positives = 145/363 (39%), Gaps = 79/363 (21%)
Query: 684 ASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELI 743
+S +S+ S+E++++ S+ + + E+E + +QE+ L+ R++ EE
Sbjct: 299 SSSSSDSDSDEVDRI------SEWKRRDEARRRELEARRRREQEE-ELRRLREQEKEEKE 351
Query: 744 QEESSEDEGEYE---------EVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQ 794
+ D GE E E+R+D + V + +G P ++ + +R +
Sbjct: 352 RRRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGR-GPPSSSDSEPEAELEREAK 410
Query: 795 KLASKEESSNSSDSKS--QSRRHLSAKER---------------------REMKKKKLPS 831
K A K +SS++ ++ Q + + +E+ R+++KKK PS
Sbjct: 411 KSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPS 470
Query: 832 DSGDLEALEGKDK-----------------EKESTVHIETHQNTSKNVAAVQPMKR---- 870
L+ L + K E+ T+ + T Q KN V +K+
Sbjct: 471 VEEKLQKLHSEIKFALKVDSPDVKRCLNALEELGTLQV-TSQILQKNTDVVATLKKIRRY 529
Query: 871 -GQKSKMKKMKEKY---KDQDEEDRELIMKLLGSAGSNKEEKGKK--GKKGKTKDEPVKK 924
K M+K E Y K + + ++ + AG KE+ +K G++ ++ P +K
Sbjct: 530 KANKDVMEKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEK 589
Query: 925 QPQKPRGGQRVSDN---IKKETPFLEVITHELQDFAVDDP--------HDDKEEQDLDQQ 973
KP N ++ E HE + + P HD +E DLD+
Sbjct: 590 AEDKPSTDLSAPVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDLHDVREGPDLDRP 649
Query: 974 GNE 976
G++
Sbjct: 650 GSD 652
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 57.0 bits (136), Expect = 9e-08
Identities = 54/281 (19%), Positives = 121/281 (43%), Gaps = 22/281 (7%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
E+K+R ++E M E + EQ + ++ +E+ E E E +E +
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQP 789
Q E E+L + E +++ E++++ ++ + E + ++T T D ++
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQ---EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711
Query: 790 QRSIQ----KLASKEESSNSSDSKSQSRRHLSAKERREM---------------KKKKLP 830
+ S++ K+ +EE + K Q + ++ EM ++++LP
Sbjct: 712 EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Query: 831 SDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEED 890
L E ++++ E ++ + + + RGQ+ KM+ +EK Q+E+
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 891 RELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRG 931
K+ G ++ K +K + ++E +++Q +K RG
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRG 872
Score = 49.7 bits (117), Expect = 1e-05
Identities = 57/355 (16%), Positives = 148/355 (41%), Gaps = 37/355 (10%)
Query: 664 VWRHQGE-----RKVRVQDEDM----ETLASCTSELISEEMEQLDGGDTSSDEDKEEHET 714
+WR + E +K+R Q+E M E L ++ +E + +++KE E
Sbjct: 274 MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQ 333
Query: 715 PVEVELMTQVDQEDITLQSGRDEL--NEELIQEESS----EDEGEYEEVRKDQDSVGEMK 768
E+ ++ +++ +Q +++ EE ++E+ ++E +E+ ++ ++ +M+
Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 769 DEGEETLNYPDTTIDLSHLQPQRS-----IQKLASKEESSNSSDSKSQSRRHLSAKERRE 823
D+ E + + ++ ++K+ +++ + +ER
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 824 MKKKKLPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKY 883
++KK+ + + E K +++E + + + + Q K ++ KM++ +EK
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 513
Query: 884 KDQDEEDRE------LIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSD 937
+Q+E+ R+ K+ ++E ++ K +D+ K Q+ R ++ +
Sbjct: 514 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE 573
Query: 938 NIKKETPFLEVITHE-----------LQDFAVDDPHDDKEEQDLDQQGNEENLFD 981
KK E + E ++ + + + +EQ+ Q EE +++
Sbjct: 574 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWE 628
Score = 47.4 bits (111), Expect = 7e-05
Identities = 47/236 (19%), Positives = 104/236 (44%), Gaps = 16/236 (6%)
Query: 664 VWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQ 723
+W H+ K++ Q++ E + E+ Q T E E E+ E E +
Sbjct: 667 LWEHE---KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Query: 724 VDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTID 783
++E + Q EE +QE+ + + + EE+ + ++ + E +++ E P+
Sbjct: 724 EEEEMMREQ-------EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Query: 784 LSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKD 843
L + + +K+ +EE + K + + +E+ +++K+ + E K
Sbjct: 777 LWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ-----EEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 844 KEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLG 899
+E + + + + + M+ GQ+ KM++ +EK + Q+E+ RE K+ G
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQ-GQEEKMREQEEKMRGQEEKMREQEEKMRG 886
Score = 45.8 bits (107), Expect = 2e-04
Identities = 57/310 (18%), Positives = 134/310 (43%), Gaps = 25/310 (8%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
E+K R Q+E M+ E I E +++ +EE ET E E Q +E++
Sbjct: 436 EKKTRDQEEKMQE-----EERIREREKKM----------REEEETMREQEEKMQKQEENM 480
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKD---EGEETLNYPDTTIDLSH 786
Q ++ + L E E E E++++ ++ + E ++ + EE
Sbjct: 481 WEQEEKEWQQQRL--PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 538
Query: 787 LQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEK 846
++ Q ++ +EE + K + K+ +E +KK + E +++EK
Sbjct: 539 MREQED--QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596
Query: 847 ESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKE 906
+ E + + + + + Q+ KM + +EK ++Q+E+ E K+ E
Sbjct: 597 KMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWE 656
Query: 907 EKGKKGKKGKT-KDEPVKKQPQKPRGGQRV--SDNIKKETPFLEVITHELQDFAVDDPHD 963
++ +K K + E +++Q + +++ + ++K+T E T + + ++
Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716
Query: 964 DKEEQDLDQQ 973
++E++ +++
Sbjct: 717 EREKKMREEE 726
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 56.6 bits (135), Expect = 1e-07
Identities = 64/317 (20%), Positives = 132/317 (41%), Gaps = 31/317 (9%)
Query: 679 DMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDEL 738
D +T S + E + +E+ L S D EE E PV + + D
Sbjct: 52 DSDTEDSGSDENLDQELLSLAKRKRS---DSEEKEPPVSQPAASSDSETS-------DSD 101
Query: 739 NEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLAS 798
+E ++ +G+ ++ K G MK + +T + + D S + ++
Sbjct: 102 DEWTFGSNKNKKKGKARKIEKK----GTMKKQANKTASSGSSDKDSS--AESSAPEEGEV 155
Query: 799 KEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGD---LEALEGKDKEKESTVHIETH 855
+ SNSS S S S +E + + L D D LE + K++E+E IE
Sbjct: 156 SDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKR 215
Query: 856 QNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKG 915
+ + + +K +K + K+ K+K +++ E+ + ++ NKE + K+ +K
Sbjct: 216 EVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKL 275
Query: 916 KTKDEPVKK-QPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQG 974
K + +++ + ++ + R ++ + K+ P + + D EE++ D +
Sbjct: 276 DKKSQAMEELKAEREKRKNRTAELLAKKQP-----------LKTSEVYSDDEEEEEDDKS 324
Query: 975 NEENLFDSLTGQPHPED 991
+E++ S T E+
Sbjct: 325 SEKSDRSSRTSSSDEEE 341
Score = 41.2 bits (95), Expect = 0.005
Identities = 55/268 (20%), Positives = 102/268 (38%), Gaps = 42/268 (15%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
+RK +E ++ + SE + D S+++K++ + + T Q +
Sbjct: 73 KRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANK 132
Query: 730 TLQSG---RDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDE------GEETLNYPDT 780
T SG +D E EE + + DS +DE GE+ + +
Sbjct: 133 TASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEED 192
Query: 781 TIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALE 840
L + + Q+L ++ E + + ++ L +++E K+KK +
Sbjct: 193 RARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQE-------- 244
Query: 841 GKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGS 900
+++EK+ I+ Q TS N K + K EK + + EL
Sbjct: 245 -EEQEKKKLTQIQESQVTSHN-----------KERRSKRDEKLDKKSQAMEEL------- 285
Query: 901 AGSNKEEKGKKGKKGKTKDEPVKKQPQK 928
K E+ K +K +T + KKQP K
Sbjct: 286 ----KAEREK--RKNRTAELLAKKQPLK 307
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 56.2 bits (134), Expect = 2e-07
Identities = 127/610 (20%), Positives = 226/610 (37%), Gaps = 93/610 (15%)
Query: 415 LLSEEEDDDVDGDVNVEKNE-TEPPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANA 473
++S E+++D DGD + +K E EPP KK+ K+K ++ + + + V
Sbjct: 113 IISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKE 172
Query: 474 K--------KYYDHKRYAAKKTQ---KTVEAAEKAFKSAEKKTKQTLKEV---------Q 513
K K HK KK + KT+ +K K+AEK ++T KEV Q
Sbjct: 173 KVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQ 232
Query: 514 TVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGAT 573
T +++ +K K + + +Q+++ RY+ DI+VH DL
Sbjct: 233 TAAKVKEVQKTPSKPK----EKEDKEKAAVSKHEQKDQYAFCRYMI--DIFVHGDL---- 282
Query: 574 SCVIKNPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTG 633
K IPP TE + S A + + E T
Sbjct: 283 ----KPGQSPAIPPPLPTEQASRPTPASPALEEK-------------EGEKKKAEKKVTS 325
Query: 634 SFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHQGERKVRVQ-----DEDMETLASCTS 688
+ K++ S K QG K+ Q DE E
Sbjct: 326 ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKK 385
Query: 689 ELISEEMEQLDGGDTSSDE--------DKEEHETP--VEVELMTQVDQEDI-------TL 731
E+EQ G E K+EH P +V+ T+ +E+I +
Sbjct: 386 ---PAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAV 442
Query: 732 QSGRDELNEELIQEE-SSEDEGEYEEVRKDQDSVGEMKDEGEETL--NYPDTTIDLSHLQ 788
++E + +++E E G+ + KD++ + +++ +L P+T D
Sbjct: 443 PGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKD----- 497
Query: 789 PQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKES 848
+K++ + + Q ++ K ++KK+ P+ S ++ + + E
Sbjct: 498 -----EKMSKAGKEVKPKPPQLQGKK--EEKPEPQIKKEAKPAISEKVQIHKQDIVKPEK 550
Query: 849 TV-HIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEE 907
TV H + + K V AV K + KK + + ++ + K S E
Sbjct: 551 TVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDK-PKPTPKGTSEVTE 609
Query: 908 KGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPHDDKEE 967
GKK K ++ E +K K ++VS +KE+ L +T + V +D
Sbjct: 610 SGKK-KTEISEKESKEKADMKHLREEKVS--TRKESLQLHNVTKAEKPARVSKDVEDVPA 666
Query: 968 QDLDQQGNEE 977
++G E+
Sbjct: 667 SKKAKEGTED 676
Score = 46.6 bits (109), Expect = 1e-04
Identities = 62/313 (19%), Positives = 125/313 (39%), Gaps = 62/313 (19%)
Query: 685 SCTSELISEEMEQLDGGDTSSDE---------------DKEEHETPVEVELMTQVDQEDI 729
S S++IS E E+ D GD +D+ DK E + E ++ T+V ++
Sbjct: 108 SLLSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKE- 166
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPD--TTIDLSHL 787
+ G++++ E+ E+ + + + E+ K + + + +T + T ++
Sbjct: 167 -KEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGG 225
Query: 788 QPQRSIQKLAS-KEESSNSSDSKSQSRRHLSAKERREMKKK------------------- 827
+ ++ Q A KE S K + + +A + E K +
Sbjct: 226 KQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPG 285
Query: 828 -------KLPSDSGD--------LEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQ 872
LP++ LE EG+ K+ E V ET + +++ K+ +
Sbjct: 286 QSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIK-----KKSE 340
Query: 873 KSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEK---GKKGKKGKTKDEPVKKQPQKP 929
K +++K + E ++ +K+ A + K+EK KK KK ++P K+ +K
Sbjct: 341 KETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKK 400
Query: 930 RGGQRVSDNIKKE 942
+ + KKE
Sbjct: 401 EKHVEPAKSPKKE 413
Score = 38.9 bits (89), Expect = 0.026
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 21/113 (18%)
Query: 413 PYLLSEEEDDDVDGDVNVEKNETEPPKGKKK-----KQKNKQLQKPQKNKPLLVDVD--- 464
P L +E+ +E+ E E K +KK K+K K+ K + K +DV+
Sbjct: 292 PPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKE 351
Query: 465 -----------LSLSAYANAKKYYDHKRYAAKKTQKTVEAAEKAFKSAEKKTK 506
+ ++A A AKK D K+ +KKT+K E + K EKK K
Sbjct: 352 PGKASETKQGTVKIAAQAAAKK--DEKKEDSKKTKKPAEVEQPKGKKQEKKEK 402
Score = 31.6 bits (70), Expect = 4.2
Identities = 24/102 (23%), Positives = 52/102 (50%), Gaps = 10/102 (9%)
Query: 878 KMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSD 937
+ KE +KD+ E+ + K+ ++EKGK +K + K++P KK K +++
Sbjct: 139 RKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGK--EKVREKEKPEKKATHK----EKIE- 191
Query: 938 NIKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENL 979
KKE P + + E + + ++K ++++ + G +E +
Sbjct: 192 --KKEKPETKTLAKEQKKAKTAEKSEEKTKKEV-KGGKQEKV 230
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 55.1 bits (131), Expect = 4e-07
Identities = 49/277 (17%), Positives = 117/277 (42%), Gaps = 16/277 (5%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
E +VR Q+ + E + EQ + +E+ E E + + +
Sbjct: 100 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 159
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKD---EGEETLNYPDTTIDLSH 786
Q G+ E ++E+ + + +VR+ + +GE + E EE + + +
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE 219
Query: 787 LQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKD--- 843
Q +++ +EE + + Q + K+ +M+K++ + + E ++
Sbjct: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
Query: 844 KEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE----------EDREL 893
K+KE T E + + + R Q+ +M++ +E+ ++Q+E E +E
Sbjct: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339
Query: 894 IMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPR 930
+ + +E+ G++ ++ + ++E V+KQ ++ R
Sbjct: 340 MWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376
Score = 48.9 bits (115), Expect = 3e-05
Identities = 44/241 (18%), Positives = 111/241 (46%), Gaps = 16/241 (6%)
Query: 691 ISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSED 750
+ E+ EQ+ G+ K+E + + E M + +E + Q + + EE +Q++ +
Sbjct: 201 MGEQEEQM--GEQEEQMQKQEEQMGEQEEQMRK-QEEQMGEQEEQVQKQEEQVQKQEEQM 257
Query: 751 EGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKS 810
+ E++R+ ++ +M+++ E+ L + T Q +++ +EE + +
Sbjct: 258 RKQEEQMREQEE---QMREQEEQMLKQKEQTEQEEQTGEQE--EQMREQEEQMREQEEQM 312
Query: 811 QSRRHLSAKERREMKKKKLPSDSGDLEALEGKDK----EKESTVHIETHQNTSKNVAAVQ 866
+ + ++ +M K++ + E K++ E++ E Q + V +
Sbjct: 313 REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE 372
Query: 867 PMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQP 926
R Q+ +M+K +E+ + Q+E+ E ++ G KE+ ++ ++ + E ++KQ
Sbjct: 373 EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQM----GEQKEQMREQEEQMGEQKEQMRKQE 428
Query: 927 Q 927
+
Sbjct: 429 E 429
Score = 43.5 bits (101), Expect = 0.001
Identities = 51/277 (18%), Positives = 113/277 (40%), Gaps = 51/277 (18%)
Query: 670 ERKVRVQDEDM---ETLASCTSELISEEMEQLDGGDTSSDEDKEE----HETPVEVELMT 722
E +VR Q+ M E E + E+ EQ+ + E +E+ E E E
Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
Query: 723 QVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKD------QDSVGEMKD---EGEE 773
Q +E + Q + EE ++E+ + + E++ K ++ GE ++ E EE
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEE 303
Query: 774 TLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDS 833
+ + Q + +++ +EE + + ++ +++ +M K
Sbjct: 304 QMREQEE-------QMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWK------- 349
Query: 834 GDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDREL 893
+E++ E Q + V + R Q+ +M+K +E+ + Q+E+
Sbjct: 350 ----------QEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQ---- 395
Query: 894 IMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPR 930
G KE+ G++ ++ + ++E + +Q ++ R
Sbjct: 396 -------MGEQKEQMGEQKEQMREQEEQMGEQKEQMR 425
Score = 40.4 bits (93), Expect = 0.009
Identities = 60/311 (19%), Positives = 134/311 (43%), Gaps = 21/311 (6%)
Query: 687 TSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITL-QSGRDELNEELIQE 745
T+E + E+ +L + +K E + ++ EL +++ + I L Q G+ E ++E
Sbjct: 5 TNEELKEKNAELQEELQLVETEKSEIQLHIK-ELKRKLETDKIPLPQEGQVREQEGQVRE 63
Query: 746 ESS---EDEGEYEE----VRKDQDSVGEMKDE-GEETLNYPDTTIDLSHLQPQRSIQKLA 797
+ E EG+ E VR+ + V E + + E+ + + + Q Q+
Sbjct: 64 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 123
Query: 798 SKEESSNSSDSKSQSRRHLSAKERRE----MKKKKLPSDSGDLEALEGKDKEKESTVHIE 853
+E+ + + Q R +E ++ ++ G + EG+ +E+E V +
Sbjct: 124 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
Query: 854 THQ-NTSKNVAAVQPMKRG-QKSKMKKMKEKYKDQDE---EDRELIMKLLGSAGSNKEEK 908
Q + Q + G Q+ +M + +E+ + Q+E E E + K G +E+
Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
Query: 909 GKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQ 968
K+ ++ + ++E ++KQ ++ R ++ ++E L+ Q+ + + EQ
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMR--EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
Query: 969 DLDQQGNEENL 979
+ + EE +
Sbjct: 302 EEQMREQEEQM 312
Score = 39.7 bits (91), Expect = 0.015
Identities = 49/271 (18%), Positives = 111/271 (40%), Gaps = 18/271 (6%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
E +VR Q+ + E + EQ + +E+ E E + + +
Sbjct: 51 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 110
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEM-----KDEG---EETLNYPDTT 781
Q G+ E ++E+ + + +VR+ + V E + EG E+ +
Sbjct: 111 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 170
Query: 782 IDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEG 841
+ + Q Q+ +E+ + + Q +E + +K G+ E
Sbjct: 171 GQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR 230
Query: 842 KDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSA 901
K +E+ E + K VQ Q+ +M+K +E+ ++Q+E+ RE ++L
Sbjct: 231 KQEEQMG----EQEEQVQKQEEQVQK----QEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
Query: 902 GSNKEEK--GKKGKKGKTKDEPVKKQPQKPR 930
++E+ G++ ++ + ++E +++Q ++ R
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMR 313
Score = 34.3 bits (77), Expect = 0.65
Identities = 40/264 (15%), Positives = 105/264 (39%), Gaps = 18/264 (6%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
E +VR Q+ + E + EQ + +E+ E E + + +
Sbjct: 72 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 131
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKD---EGEETLNYPDTTIDLSH 786
Q G+ E ++E+ + + +VR+ + V E + E E + + +
Sbjct: 132 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 191
Query: 787 LQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEK 846
Q ++ +EE + + Q + ++ +M+K++ G+ E K +E+
Sbjct: 192 GQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQE--EQMGEQEEQVQKQEEQ 249
Query: 847 ESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKE 906
+ + + + M+ ++ +K+ K+Q E++ + G +E
Sbjct: 250 VQKQEEQMRKQEEQMREQEEQMREQEEQMLKQ-----KEQTEQEEQ--------TGEQEE 296
Query: 907 EKGKKGKKGKTKDEPVKKQPQKPR 930
+ ++ ++ + ++E +++Q ++ R
Sbjct: 297 QMREQEEQMREQEEQMREQEEQMR 320
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 55.1 bits (131), Expect = 4e-07
Identities = 51/264 (19%), Positives = 121/264 (45%), Gaps = 21/264 (7%)
Query: 721 MTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDT 780
+ Q +E + Q + + EE IQE+ + + E++R+ + EM E EE + +
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQE----EMMWEKEEKMRRQEE 337
Query: 781 TIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALE 840
+ + R +++ ++E + K Q + +E+R+ ++ K+ + E
Sbjct: 338 MM-WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 396
Query: 841 GKDKEKESTVHIETHQ--NTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLL 898
K +E+E + + + + + + + Q+ KM++ +EK ++Q+++ RE K+
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456
Query: 899 GSAGSNKEEKGKKG-KKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFA 957
+E++ K G ++GK ++ K Q Q+ + +R + I++ Q+
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK-MRRQEEKIRE------------QEKK 503
Query: 958 VDDPHDDKEEQDLDQQGNEENLFD 981
+ + + EQ+ Q EE +++
Sbjct: 504 IREQEEKIREQEEMMQEQEEKMWE 527
Score = 52.4 bits (124), Expect = 2e-06
Identities = 54/297 (18%), Positives = 133/297 (44%), Gaps = 16/297 (5%)
Query: 661 ESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL 720
E +WR E K++ ++E ++ E I E+ E++ + E +E+ + E+
Sbjct: 287 EEKMWRQ--EEKIQEREEKIQE----QEEKIREQEEKMRRQEEMMWEKEEKMRR--QEEM 338
Query: 721 MTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDT 780
M + +++ L+ E + QEE ++E + E K Q+ +M + EE + +
Sbjct: 339 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-EEKIREQEE 397
Query: 781 TIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALE 840
I Q +K+ +EE + + Q + +E+ +++K+ + E
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQ-----EEKMRRQEEKIREQEKKIREQE 452
Query: 841 GKDKEKESTVHIETHQNTSKN--VAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLL 898
K +E+E + + + + + + + Q+ KM++ +EK ++Q+++ RE K+
Sbjct: 453 EKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 512
Query: 899 GSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQD 955
+E++ K ++ + E +K ++ +R + ++++ L ++Q+
Sbjct: 513 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 30.8 bits (68), Expect = 7.2
Identities = 44/224 (19%), Positives = 102/224 (45%), Gaps = 28/224 (12%)
Query: 755 EEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRR 814
EE+ K++D++ +L TI L+ + + KL K + S S+ Q
Sbjct: 184 EELTKERDAL---------SLELYRNTITDEELKEKNA--KLQEKLQLVESEKSEIQ--- 229
Query: 815 HLSAKE-RREMKKKKLPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQK 873
L+ KE +R++++ KL L+A ++ +V + +N + + Q+
Sbjct: 230 -LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN-ELWNRLNQQQE 287
Query: 874 SKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQ 933
KM + +EK ++++E+ +E +E+ ++ +K + ++E + ++ +K R +
Sbjct: 288 EKMWRQEEKIQEREEKIQE-----------QEEKIREQEEKMRRQEEMMWEKEEKMRRQE 336
Query: 934 RVSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEE 977
+ +++ LE HE + + +EE+ +Q+ +E
Sbjct: 337 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 380
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 54.3 bits (129), Expect = 6e-07
Identities = 64/319 (20%), Positives = 138/319 (43%), Gaps = 26/319 (8%)
Query: 666 RHQGERKVRVQDEDMETLASC--TSELISEEMEQLDGGDTSSDEDKEE-HETPVEVELMT 722
+ Q E K+R Q++ E A E I E+ E++ + +E+ HE E
Sbjct: 412 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 471
Query: 723 QVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTI 782
+ +QE++ Q + EE+ +++ E E E++RK ++ V EE + + I
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE-EKIRKQEEKVWRQ----EEKIREQEEKI 526
Query: 783 DLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGK 842
+ R +K+ +EE + K + + +E+R+ ++ K+ + E K
Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEE-KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585
Query: 843 DKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAG 902
+E + + K + M + Q+ K+++ +EK ++Q+E+ RE K+
Sbjct: 586 VWRQEEKIR----EQEEKRQEQEEKMWK-QEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 903 SNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPH 962
+E++ K G++ + E +K ++ R + I++ Q+ + +
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE------------QEKKIREQE 688
Query: 963 DDKEEQDLDQQGNEENLFD 981
+ EQ+ Q EE +++
Sbjct: 689 EKIREQEEMMQEQEEKMWE 707
Score = 50.1 bits (118), Expect = 1e-05
Identities = 56/244 (22%), Positives = 105/244 (43%), Gaps = 19/244 (7%)
Query: 661 ESCVWRHQGERKVRVQDE---DMETLASCTSELISEEMEQLDGGDTSSDEDKE-EHETPV 716
E VWR E K+R Q+E + E E I E+ E + +++K E E
Sbjct: 509 EEKVWRQ--EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 717 EVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKD---EGEE 773
E E +E I Q + EE I+E+ + + + E++ K ++ + E ++ E EE
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626
Query: 774 TLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDS 833
+ + I Q +K+ +EE + K Q + +E +++K+
Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ-----EETMWRQEEKIREQE 681
Query: 834 GDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDREL 893
+ E K +E+E E Q + + + Q+ KM++ +EK + Q+E+ E
Sbjct: 682 KKIREQEEKIREQE-----EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736
Query: 894 IMKL 897
++L
Sbjct: 737 EVRL 740
Score = 43.9 bits (102), Expect = 8e-04
Identities = 61/300 (20%), Positives = 134/300 (44%), Gaps = 31/300 (10%)
Query: 661 ESCVWRHQG-----ERKVRVQDEDM--ETLASCTSELISEEMEQLDGGDTSSDEDK--EE 711
E+ +WR + E K+R Q++ M + E I EE ++ + + E+K E+
Sbjct: 429 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488
Query: 712 HETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKD-- 769
E + E M + +E I Q + EE I+E+ + + E++ + ++ + E ++
Sbjct: 489 EEIWRQKEKMHE-QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547
Query: 770 EGEETLNYPDTTIDLSHLQPQ-----RSIQKLASKEESSNSSDSK--SQSRRHLSAKERR 822
EE ++ + + Q Q R +K+ +EE + K Q + +E+
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607
Query: 823 EMKKKKLPSDSGDLEALEGKDKEKESTVHI--ETHQNTSKNVAAVQPMKRGQKSKMK--- 877
+++K+ ++ E K +E+E + E Q + + + Q+ KM+
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 878 ----KMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGK---KGKKGKTKDEPVKKQPQKPR 930
+ +EK ++Q+++ RE K+ +E++ K + +K ++E +++Q +K R
Sbjct: 668 ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727
Score = 42.7 bits (99), Expect = 0.002
Identities = 52/276 (18%), Positives = 124/276 (44%), Gaps = 32/276 (11%)
Query: 658 KVDESCVWRH---QGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHET 714
+V+E+ +W Q E K+ Q+E ++ E I E+ E++ + E +E+
Sbjct: 284 QVEENELWNRLNQQQEEKMWRQEEKIQEW----EEKIQEQEEKIREQEEKIREQEEKMRR 339
Query: 715 PVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEET 774
+ E+M + +++ + E E++ ++E E E E++R+ + EM E EE
Sbjct: 340 --QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKMRRQE----EMMWEKEEK 392
Query: 775 LNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSG 834
+ R +++ ++E + K Q + +E+R+ ++ K+
Sbjct: 393 I---------------RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 437
Query: 835 DLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE--EDRE 892
+ E K +E+E + + + + KR ++ +M + +EK +Q+E +E
Sbjct: 438 KIREQEEKIREQEKKMW-RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
Query: 893 LIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQK 928
+ + +E+ ++ +K + ++E +++Q +K
Sbjct: 497 KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 36.2 bits (82), Expect = 0.17
Identities = 49/253 (19%), Positives = 107/253 (42%), Gaps = 29/253 (11%)
Query: 731 LQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSH---L 787
L RD L+ EL + +++E + + + + ++ E LN + L L
Sbjct: 198 LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL 257
Query: 788 QPQRSIQKLAS---KEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDK 844
PQ+ +Q A KE S S+ ++Q + + +++K+ ++ E K +
Sbjct: 258 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
Query: 845 EKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSN 904
E+E + R Q+ K+++ +EK + Q+E E K+
Sbjct: 318 EQEEKI-------------------REQEEKIREQEEKMRRQEEMMWEKEEKM----RRQ 354
Query: 905 KEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPHDD 964
+E +K +K + ++E + ++ +K R + + +++ LE HE + +
Sbjct: 355 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 414
Query: 965 KEEQDLDQQGNEE 977
+EE+ +Q+ +E
Sbjct: 415 EEEKIREQEKRQE 427
Score = 33.9 bits (76), Expect = 0.85
Identities = 32/154 (20%), Positives = 66/154 (42%), Gaps = 12/154 (7%)
Query: 661 ESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL 720
E +W+ E K+R Q+E ++ E + EQ + ++ E+ E E E
Sbjct: 604 EEKMWKQ--EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 661
Query: 721 MTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKD---EGEETLNY 777
Q +E + Q EE I+E+ + + E++R+ ++ + E ++ E EE +
Sbjct: 662 KMQEQEETMWRQ-------EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 714
Query: 778 PDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQ 811
+ + + +R +K+ +E + K Q
Sbjct: 715 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor
[Homo sapiens]
Length = 513
Score = 53.9 bits (128), Expect = 8e-07
Identities = 77/365 (21%), Positives = 141/365 (38%), Gaps = 48/365 (13%)
Query: 676 QDEDMETLASCTSELISEEM--EQLDGGDTSSDEDKEEH--------------ETPVEVE 719
QD +T + + EL +E+ + +GGD++ + + EEH + ++ E
Sbjct: 155 QDSAQDTTSE-SRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDE 213
Query: 720 LMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPD 779
M D E I + G +N ++ S++ GE E QDS G + L +P
Sbjct: 214 GMQSDDPESIRSERGNSRMNSAGMK---SKESGENSEQANTQDS------GGSQLLEHPS 264
Query: 780 TTI----------DLSHLQPQRSIQKLAS-KEESSNSSDSKSQSRRHLSAKERREMKKKK 828
I D S L +++++ S E+SNS D+ R S + +E K+
Sbjct: 265 RKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKEN 324
Query: 829 LPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQK-SKMKKMKEKYKDQD 887
L + + + ++G E ++ + +N+S++ V RG E +D D
Sbjct: 325 LSQE--ESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSD 382
Query: 888 EEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLE 947
+ + L S ++EE+ ++ P+ P ++ +E
Sbjct: 383 SSEEDSSHTLSHSKSESREEQADSESSESLNFS--EESPESPED----ENSSSQEGLQSH 436
Query: 948 VITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMT 1007
+ E Q DD + QD + + N +S + ED L I I + T+
Sbjct: 437 SSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSS--EEDGQLKNIEIESRKLTVD 494
Query: 1008 NYKYK 1012
Y K
Sbjct: 495 AYHNK 499
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 53.9 bits (128), Expect = 8e-07
Identities = 77/365 (21%), Positives = 141/365 (38%), Gaps = 48/365 (13%)
Query: 676 QDEDMETLASCTSELISEEM--EQLDGGDTSSDEDKEEH--------------ETPVEVE 719
QD +T + + EL +E+ + +GGD++ + + EEH + ++ E
Sbjct: 139 QDSAQDTTSE-SRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDE 197
Query: 720 LMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPD 779
M D E I + G +N ++ S++ GE E QDS G + L +P
Sbjct: 198 GMQSDDPESIRSERGNSRMNSAGMK---SKESGENSEQANTQDS------GGSQLLEHPS 248
Query: 780 TTI----------DLSHLQPQRSIQKLAS-KEESSNSSDSKSQSRRHLSAKERREMKKKK 828
I D S L +++++ S E+SNS D+ R S + +E K+
Sbjct: 249 RKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKEN 308
Query: 829 LPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQK-SKMKKMKEKYKDQD 887
L + + + ++G E ++ + +N+S++ V RG E +D D
Sbjct: 309 LSQE--ESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSD 366
Query: 888 EEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLE 947
+ + L S ++EE+ ++ P+ P ++ +E
Sbjct: 367 SSEEDSSHTLSHSKSESREEQADSESSESLNFS--EESPESPED----ENSSSQEGLQSH 420
Query: 948 VITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMT 1007
+ E Q DD + QD + + N +S + ED L I I + T+
Sbjct: 421 SSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSS--EEDGQLKNIEIESRKLTVD 478
Query: 1008 NYKYK 1012
Y K
Sbjct: 479 AYHNK 483
>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sapiens]
Length = 558
Score = 53.9 bits (128), Expect = 8e-07
Identities = 73/355 (20%), Positives = 145/355 (40%), Gaps = 42/355 (11%)
Query: 717 EVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDE--GEET 774
EV ++ QE LQ+ ++ EE+ + + +++ D + E + E+
Sbjct: 220 EVSSKNRIPQEKCILQT-------DVKVEENPDADSDFDAKSSADDEIEETRVNCRREKV 272
Query: 775 LNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSG 834
+ P+ D H + Q + S+E ++ SR ++R + ++K D
Sbjct: 273 IETPEN--DFKHHRSQNH-SRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSRDQE 329
Query: 835 DLEALEGKDKEKESTVHIET---------HQNTSKNVAAVQPMKRGQKSKMKKMKEKYKD 885
+ KE++S H E H+ K A Q + + K +K +EKY
Sbjct: 330 NHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQ 389
Query: 886 QDEE-DRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETP 944
+++E DR+ + + EKG+K +K K K+E +K + ++ + D K+E
Sbjct: 390 REQERDRQQ------NDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVG 443
Query: 945 FLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYT 1004
+ QD P+ +++ LDQ+ + + + + + E P
Sbjct: 444 VQS--SERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQE----------KPSN 491
Query: 1005 TMTNYKYKVKLTPGVQKKGKAAKTALNSFMHSKEATAREKDLFRSVKDTDLSRNI 1059
+ ++ K +LT Q+KGK + + SK A ++ S +D L+R +
Sbjct: 492 SESSLGAKHRLTEEGQEKGKEQERPPEAV--SKFAKRNNEETVMSARDRYLARQM 544
Score = 48.5 bits (114), Expect = 3e-05
Identities = 106/556 (19%), Positives = 199/556 (35%), Gaps = 75/556 (13%)
Query: 399 LKLQTNHVTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKP 458
L +T + +L+ P + + DDD + V+ E + E K + KQ ++QK
Sbjct: 12 LPKKTQQLHPVLQKPSVFGNDSDDDDETSVS-ESLQREAAKKQAMKQTKLEIQKALAEDA 70
Query: 459 LLVDVDLSLSAYANAKKYYDHKRYAAK-KTQKTVEAAEKAFKSAEKKTKQTL-KEVQTVT 516
+ + D K+ + K K + K + KA + +K+ ++ + K++Q
Sbjct: 71 TVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQRER 130
Query: 517 SIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCV 576
++K + +K + S+ + ++++ E D+ DL G +
Sbjct: 131 EMEKGE---FDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHL 187
Query: 577 IKNPTGEPIPPRTLTEAGTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGSFM 636
+ GE P+ C + + + ++VS
Sbjct: 188 LNQAVGEEEVPK----------CSFREARSGIKEEKSRGFSNEVSS-------------- 223
Query: 637 IRGKKNFLPPSYLMMGFSFLFKVDESCVWRHQGERKVRVQDEDMETLASCTSELISEEME 696
KN +P ++ KV+E+ + K DE ET +C E + E E
Sbjct: 224 ----KNRIPQEKCILQTDV--KVEENPDADSDFDAKSSADDEIEETRVNCRREKVIETPE 277
Query: 697 QLDGGDTSSDEDKEEHETPVEVE-LMTQVDQEDITLQSGRDELNEELIQEESSEDEGEY- 754
D + +P E T+ + G ++ ++ Q++S + E Y
Sbjct: 278 N----DFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSRDQENHYT 333
Query: 755 -EEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSR 813
+ RK++DS + ++ D + QR K E S+ +
Sbjct: 334 DRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQE 393
Query: 814 RHLSAKERREMKKKKLPSDSGDLEALEGKDKEKESTVHIETHQNTSK------NVAAVQP 867
R R+ + PS+ G+ E + K KE+ V E ++N K VQ
Sbjct: 394 RD------RQQNDQNRPSEKGEKEE-KSKAKEEHMKVRKERYENNDKYRDREKREVGVQS 446
Query: 868 MKRGQKSKMK----KMKEKYKDQDEEDRELIM---------------KLLGSAGSNKEEK 908
+R Q K + K+K+ DQ+ ++ M LG+ EE
Sbjct: 447 SERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTEEG 506
Query: 909 GKKGKKGKTKDEPVKK 924
+KGK+ + E V K
Sbjct: 507 QEKGKEQERPPEAVSK 522
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 53.5 bits (127), Expect = 1e-06
Identities = 62/283 (21%), Positives = 124/283 (43%), Gaps = 22/283 (7%)
Query: 661 ESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKE--EHETPVEV 718
E +W E K+R Q++ M E + E+ E+L + E K+ + E +
Sbjct: 485 EDQMWEQ--EEKMRDQEQKMWD----QEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
Query: 719 ELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYP 778
E TQ +QE T +++ EE E + E EE+ ++Q+ E E EE +
Sbjct: 539 EKKTQ-EQEKKTWDQ-EEKMREEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQ 593
Query: 779 DTTIDLSHLQPQRSIQKLASKEES--SNSSDSKSQSRRHL--SAKERREMKKKKLPSDSG 834
+ + + Q +K+ +EE + K Q + + +E+ + +++K+
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 835 DLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELI 894
+ E K +E+E E Q + + + +GQ+ KM++ +EK + Q+E+
Sbjct: 654 KMREQEEKMREQE-----EKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708
Query: 895 MKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSD 937
K+ G ++ + K+ + +D+ K Q + P +R S+
Sbjct: 709 EKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751
Score = 50.1 bits (118), Expect = 1e-05
Identities = 53/282 (18%), Positives = 130/282 (46%), Gaps = 36/282 (12%)
Query: 664 VWRHQGE-----RKVRVQDEDM----ETLASCTSELISEEMEQLDGGDTSSDEDKEEHET 714
+WR + E +K+R Q+E M E L ++ +E + +++KE E
Sbjct: 236 MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQ 295
Query: 715 PVEVELMTQVDQEDITLQSGRDEL--NEELIQEESS----EDEGEYEEVRKDQDSVGEMK 768
E+ ++ +++ +Q +++ EE ++E+ ++E +E+ ++ ++ +M+
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 769 DEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKK 828
D+ EE + D ++L KEE + + + +ER ++KK
Sbjct: 356 DQ-EERMWEQD--------------ERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 829 LPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE 888
+ + + E K +++E + + + + Q K ++ KM++ +EK +Q+E
Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 889 EDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPR 930
+ R+ ++ G +E+K + +K + +++ + +Q +K R
Sbjct: 461 KIRDQ-EEMWG-----QEKKMWRQEKMREQEDQMWEQEEKMR 496
Score = 48.9 bits (115), Expect = 3e-05
Identities = 57/277 (20%), Positives = 119/277 (42%), Gaps = 20/277 (7%)
Query: 661 ESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDED---KEEHETPVE 717
E +WR + K+R Q++ M ++ +E + D + ++D +E+ E E
Sbjct: 472 EKKMWRQE---KMREQEDQMWEQEE---KMRDQEQKMWDQEERMWEQDERLREKEERMRE 525
Query: 718 VELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNY 777
+ M Q +++ + +++ + QEE +E E K EM E EE +
Sbjct: 526 QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 585
Query: 778 PDTTIDLSHLQPQRSIQKLASKEESSNSSDSKS-QSRRHLSAKERREM---KKKKLPSDS 833
+ + + +K+ +EE + K + +E+ EM +++K+
Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645
Query: 834 GDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDREL 893
+ E K +E+E E + + + + R Q+ KM+ +EK ++Q+E+ R
Sbjct: 646 EKMWEQEEKMREQE-----EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
Query: 894 IMKLLGSAGS--NKEEKGKKGKKGKTKDEPVKKQPQK 928
K+ G +EEK ++ + K+E ++ Q +K
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK 737
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 53.1 bits (126), Expect = 1e-06
Identities = 67/324 (20%), Positives = 144/324 (44%), Gaps = 21/324 (6%)
Query: 658 KVDESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVE 717
K+ E + E K+R Q+E M E++ E+ E++ + E KEE +E
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRR----QEEMMWEKEEKMRRQEEMMWE-KEEKMRRLE 369
Query: 718 VELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNY 777
E+M + +++ L+ E + QEE ++E + E K Q+ +M + EE +
Sbjct: 370 -EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-EEKIRE 427
Query: 778 PDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLE 837
+ I + R +K+ +E+ + K Q + + +E + +++++ +
Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIRE--EEKRQEQEEMWRQEEKIREQEEIWRQKEKMH 485
Query: 838 ALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKL 897
E K++E E + + R Q+ KM + +EK ++Q+E+ RE K+
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKI------REQEEKMWRQEEKIREQEEKIREQEEKI 539
Query: 898 LGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFA 957
+E++ K G+ ++E +++Q + R +++ + +K E I Q+
Sbjct: 540 REQEEMMQEQEEKMGE----QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIRE--QEEK 593
Query: 958 VDDPHDDKEEQDLDQQGNEENLFD 981
+ + + EQ+ Q EE +++
Sbjct: 594 IWEQEEKIREQEEMMQEQEEKMWE 617
Score = 47.8 bits (112), Expect = 6e-05
Identities = 55/271 (20%), Positives = 119/271 (43%), Gaps = 37/271 (13%)
Query: 666 RHQGERKVRVQDEDMETLASC--TSELISEEMEQLDGGDTSSDEDKEE-HETPVEVELMT 722
+ Q E K+R Q++ E A E I E+ E++ + +E+ HE E
Sbjct: 398 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 457
Query: 723 QVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTI 782
+ +QE++ Q + EE+ +++ E E E++RK ++ V EE ++ + I
Sbjct: 458 RQEQEEMWRQEEKIREQEEIWRQK--EKMHEQEKIRKQEEKVWRQ----EEKMHDQEEKI 511
Query: 783 DLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGK 842
+ R +K+ +EE + K + + + ++ +M +++ E ++ +
Sbjct: 512 REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE--------EKMQEQ 563
Query: 843 DKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE---EDRELIMKLLG 899
+K + I R Q+ K+++ KEK ++Q+E E E I +
Sbjct: 564 EKMRRQEEKI-----------------REQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606
Query: 900 SAGSNKEEKGKKGKKGKTKDEPVKKQPQKPR 930
+E+ ++ +K ++E +++Q +K R
Sbjct: 607 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637
Score = 44.3 bits (103), Expect = 6e-04
Identities = 47/265 (17%), Positives = 117/265 (44%), Gaps = 33/265 (12%)
Query: 716 VEVELMTQVDQEDI--TLQSGRDEL---NEELIQEESSEDEGEYEEVRKDQDSVGEMKDE 770
V +L QV++ ++ L ++E EE IQE + + + E++R+ ++ + E ++
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE- 335
Query: 771 GEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKK--KK 828
K+ +EE + K + + + ++ +M++ +
Sbjct: 336 ------------------------KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM 371
Query: 829 LPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE 888
+ + LE K E+E E + + + Q ++ Q++KM + +EK ++Q+E
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEE 430
Query: 889 EDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEV 948
+ RE K+ E++ + ++ + + E + +Q +K R + + +K ++
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI 490
Query: 949 ITHELQDFAVDDPHDDKEEQDLDQQ 973
E + + ++ D+EE+ +Q+
Sbjct: 491 RKQEEKVWRQEEKMHDQEEKIREQE 515
Score = 43.5 bits (101), Expect = 0.001
Identities = 48/245 (19%), Positives = 104/245 (42%), Gaps = 17/245 (6%)
Query: 661 ESCVWRHQG-----ERKVRVQDEDM--ETLASCTSELISEEMEQLDGGDTSSDEDKEEHE 713
E+ +WR + E K+R Q++ M + E I EE ++ + + E+K +
Sbjct: 415 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 474
Query: 714 TPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEE 773
+ + +QE I Q + EE + ++ + + E++ + ++ + E EE
Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ----EE 530
Query: 774 TLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDS-KSQSRRHLSAKERREMKKKKLPSD 832
+ + I Q +K+ +EE + + Q + +E+ +K+K+
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 833 SGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRE 892
+ E K +E+E E Q + + + Q+ KM++ +EK + Q+E+ E
Sbjct: 591 EEKIWEQEEKIREQE-----EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 645
Query: 893 LIMKL 897
++L
Sbjct: 646 QEVRL 650
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 53.1 bits (126), Expect = 1e-06
Identities = 64/329 (19%), Positives = 140/329 (42%), Gaps = 36/329 (10%)
Query: 658 KVDESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVE 717
K+ E + E K+R Q+E M E++ E+ E++ + E +E+ +
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRR----QEEMMWEKEEKMRRQEEMMWEKEEKMRR--Q 429
Query: 718 VELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNY 777
E+M + +++ L+ E + QEE ++E + E K Q+ +M + EE +
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-EEKIRE 488
Query: 778 PDTTIDLSHLQPQRSIQKLASKE---ESSNSSDSKSQSRRHLSAKERREM--KKKKLPSD 832
+ I + R +K+ +E E + + R+ +E+ E+ +K+K+
Sbjct: 489 QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548
Query: 833 SGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRE 892
+ E K +E +H + + R Q+ K+ + +EK ++Q+E+ RE
Sbjct: 549 EEKIRKQEEKMWRQEEKMHDQEEKI------------REQEEKVWRQEEKIREQEEKIRE 596
Query: 893 LIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHE 952
K+ +E++ K G++ + E +K ++ +R + I++
Sbjct: 597 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE----------- 645
Query: 953 LQDFAVDDPHDDKEEQDLDQQGNEENLFD 981
Q+ + + + EQ+ Q EE +++
Sbjct: 646 -QEKKIREQEEKIREQEEMMQEQEEKMWE 673
Score = 48.1 bits (113), Expect = 4e-05
Identities = 53/249 (21%), Positives = 108/249 (43%), Gaps = 30/249 (12%)
Query: 661 ESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL 720
E+ +WR E K+R Q+E + E + + E++ + +E+K + + + +
Sbjct: 476 EAKMWRQ--EEKIREQEEKIRE----QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 721 MTQVDQEDITLQSGRDELNEELI---------QEESSEDEGEYEEVRKDQDSVGEMKD-- 769
+QE+I Q + EE I QEE D+ E ++R+ ++ V ++
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE--KIREQEEKVWRQEEKI 587
Query: 770 -EGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKK 828
E EE + + I Q +K+ +EE + K Q + +E+ +++K
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ-----EEKMRRQEEK 642
Query: 829 LPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE 888
+ + E K +E+E E Q + + + Q+ KM++ +EK + Q+E
Sbjct: 643 IREQEKKIREQEEKIREQE-----EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 697
Query: 889 EDRELIMKL 897
+ E ++L
Sbjct: 698 KMWEQEVRL 706
Score = 47.4 bits (111), Expect = 7e-05
Identities = 59/286 (20%), Positives = 122/286 (42%), Gaps = 24/286 (8%)
Query: 661 ESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL 720
E +W + E K+R Q+E M EL + EQ E+K + E + +
Sbjct: 416 EEMMW--EKEEKMRRQEEMMWEKEEKIRELEEKMHEQ---EKIREQEEKRQEEEKIREQE 470
Query: 721 MTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGE--MKDEGEETLNYP 778
Q + + Q + EE I+E+ E EE +Q+ + E + E EE
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQE-EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 779 DTTIDLSHLQPQRSIQKLASKEESSNSSDSK---SQSRRHLSAKERREMKKK------KL 829
+ + + Q+ +K+ +EE + K + + H ++ RE ++K K+
Sbjct: 530 EKIREQEEIWRQK--EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587
Query: 830 PSDSGDLEALEGKDKEKESTVHIETHQ--NTSKNVAAVQPMKRGQKSKMKKMKEKYKDQD 887
+ E K +E+E + + + + + + Q+ KM++ +EK ++Q+
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE 647
Query: 888 EEDRELIMKLLGSAGSNKEEKGK---KGKKGKTKDEPVKKQPQKPR 930
++ RE K+ +E++ K + +K ++E +++Q +K R
Sbjct: 648 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693
Score = 34.3 bits (77), Expect = 0.65
Identities = 51/233 (21%), Positives = 107/233 (45%), Gaps = 25/233 (10%)
Query: 755 EEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRR 814
EE+ K++D++ +L TI L+ + + KL K + S S+ Q
Sbjct: 257 EELTKERDAL---------SLELYRNTITDEELKEKNA--KLQEKLQLVESEKSEIQ--- 302
Query: 815 HLSAKE-RREMKKKKLPSDSGDLEALE---GKDKEKEST-VHIETHQNTSKNVAAVQPMK 869
L+ KE +R++++ KL L+A GK+ + S + + +N N Q +
Sbjct: 303 -LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 361
Query: 870 R--GQKSKMKKMKEKYKDQDE---EDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKK 924
+ Q+ K+++ +EK ++Q+E E E I + +E +K +K + ++E + +
Sbjct: 362 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 421
Query: 925 QPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEE 977
+ +K R + + +++ LE HE + + +EE+ +Q+ +E
Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 474
Score = 33.9 bits (76), Expect = 0.85
Identities = 38/167 (22%), Positives = 71/167 (42%), Gaps = 30/167 (17%)
Query: 661 ESCVWRHQG-----ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETP 715
E VWR + E K+R Q+E + E +++E E+ G E+ E
Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKIR-----EQEEMTQEQEEKMG---------EQEEKM 622
Query: 716 VEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKD---EGE 772
E E Q +E + Q EE I+E+ + + E++R+ ++ + E ++ E E
Sbjct: 623 CEQEEKMQEQEEKMRRQ-------EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Query: 773 ETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQS-RRHLSA 818
E + + + + +R +K+ +E + K Q + HL A
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 52.8 bits (125), Expect = 2e-06
Identities = 71/317 (22%), Positives = 139/317 (43%), Gaps = 43/317 (13%)
Query: 668 QGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVE-----VELMT 722
Q R + + ++L +EL S + +L+ + S + EE T V+ +
Sbjct: 435 QISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKIL 494
Query: 723 QVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTI 782
++++E+ L + L E++QE+ S + + KD MK++ + + TI
Sbjct: 495 KMEKENQRLSKKVEILENEIVQEKQSLQN--CQNLSKDL-----MKEKAQL-----EKTI 542
Query: 783 DLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGK 842
+ +R I+ L + E N + S + R +SA+ R K
Sbjct: 543 ETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV-------------------K 583
Query: 843 DKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAG 902
D EKE+ + E+ + TS ++ ++ KR ++KK E YK++ E EL +L
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKR----QIKKELEHYKEKGERAEELENELHHLEK 639
Query: 903 SNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPH 962
N E KK K E ++ Q+ +R + +KK + +T +L+ +++ +
Sbjct: 640 EN-ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLE--SLEKEN 696
Query: 963 DDKEEQDLDQQGNEENL 979
+E++L+ + N E+L
Sbjct: 697 SQLDEENLELRRNVESL 713
Score = 34.7 bits (78), Expect = 0.50
Identities = 80/360 (22%), Positives = 134/360 (37%), Gaps = 56/360 (15%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL-------MT 722
ER+ R + +++ + T +L S E E +S D+E E VE M
Sbjct: 669 ERENRKLKKTLDSFKNLTFQLESLEKE-------NSQLDEENLELRRNVESLKCASMKMA 721
Query: 723 QVDQEDITLQSGRDELNEELIQEESSEDEGEYEEV--------------------RKDQD 762
Q+ E+ L+S +++L + L ++S + E EV +K Q
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 763 SVGEMKDEGEETL----NYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSA 818
E++D E N + I L+ K +E S D K + +
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 819 KERREMKKKKLPSDSGDLEALEGKDKE--------KESTVHIETHQNTSKNVA--AVQPM 868
+++ E+K L ++ + LE ++K KES V ++ + +K + A +
Sbjct: 842 RQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDI 901
Query: 869 KRGQKSKMKKMKEKYKDQD-EEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQ 927
K + + EK K Q D E + L G NKE + T D K
Sbjct: 902 KTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER--LLHDEQSTDDSRYKLLES 959
Query: 928 KPRGGQRVSDNIKKE-----TPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDS 982
K + S IK+E LE T+ Q + K + L Q+ +EE + S
Sbjct: 960 KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQS 1019
Score = 32.7 bits (73), Expect = 1.9
Identities = 38/231 (16%), Positives = 97/231 (41%), Gaps = 36/231 (15%)
Query: 302 KIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRA 361
K+ +++ K L+ EK+ LKK + K + E L+ + + ++ + ++ L+ ++
Sbjct: 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKK 778
Query: 362 IQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEED 421
IQ + S L ++ + + + ++ELK+ + + L + L +E
Sbjct: 779 IQQLESEL-------------QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETS 825
Query: 422 DDVDGDVNVEKNETEPPKGKKKKQKNKQLQK-------------PQKNKPLLVDVDLSLS 468
+EK++ + K K+ ++ +++ ++NK L ++ +
Sbjct: 826 -------QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE 878
Query: 469 AYANAKKYYDHKRYAAKKTQ---KTVEAAEKAFKSAEKKTKQTLKEVQTVT 516
+ K+ + K+ KT+ + S + KT+Q +++ +T
Sbjct: 879 SCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLT 929
Score = 31.6 bits (70), Expect = 4.2
Identities = 65/311 (20%), Positives = 134/311 (43%), Gaps = 22/311 (7%)
Query: 212 KVDEKLETKDIEKVLVSLQKAEDYMKTTSNFSGKGYIIQKREIKPCLEADKPVEDILTYE 271
++ + KDIEK L E +T+S S + +KR+IK LE K + E
Sbjct: 575 QISAEARVKDIEKENKILH--ESIKETSSKLSKIEF--EKRQIKKELEHYKEKGE--RAE 628
Query: 272 EFHPFLFSQHSQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHE 331
E L + ++ + + + KIE + + L++E + LKK + K+
Sbjct: 629 ELENELHHLEKENELLQKKITNLKIT--CEKIEALEQENSELERENRKLKKTLDSFKNLT 686
Query: 332 NRLEALQQAQEIDKLKGELIEMNLQIVD--------RAIQVVRSALANQIDWTEIGL-IV 382
+LE+L+ +E +L E +E+ + +Q+ L ++ + + GL ++
Sbjct: 687 FQLESLE--KENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL 744
Query: 383 KEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKK 442
K + + + + + + L ++ + L N ++ + ++ D+ +E N+T ++
Sbjct: 745 KASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ-DLEME-NQTLQKNLEE 802
Query: 443 KKQKNKQLQKPQK-NKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQKTVEAAEKAFKSA 501
K +K+L++ +K NK L + +K R A+ T+E +
Sbjct: 803 LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Query: 502 EKKTKQTLKEV 512
EK+ K KE+
Sbjct: 863 EKENKTLSKEI 873
Score = 30.8 bits (68), Expect = 7.2
Identities = 41/223 (18%), Positives = 99/223 (44%), Gaps = 18/223 (8%)
Query: 768 KDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLS---AKERREM 824
+DE ET+ D H P S +++ + +++SR+HLS A + ++
Sbjct: 204 RDEHSETIIELSEERDGLHFLPHASS---SAQSPCGSPGMKRTESRQHLSVELADAKAKI 260
Query: 825 KKKKLPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYK 884
++ + + + L+ K + ++ + ++ Q + N+ + R + ++ ++EK
Sbjct: 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAV 320
Query: 885 DQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETP 944
D+ + E+ S +E+ + K + E +K+ Q + + ++ + T
Sbjct: 321 RVDKLESEV---------SRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTR 371
Query: 945 FLEVITHELQDFAVD---DPHDDKEEQDLDQQGNEENLFDSLT 984
HEL+ + HD + E+D+D++ EE + +++T
Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMT 414
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 52.8 bits (125), Expect = 2e-06
Identities = 71/317 (22%), Positives = 139/317 (43%), Gaps = 43/317 (13%)
Query: 668 QGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVE-----VELMT 722
Q R + + ++L +EL S + +L+ + S + EE T V+ +
Sbjct: 435 QISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKIL 494
Query: 723 QVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTI 782
++++E+ L + L E++QE+ S + + KD MK++ + + TI
Sbjct: 495 KMEKENQRLSKKVEILENEIVQEKQSLQN--CQNLSKDL-----MKEKAQL-----EKTI 542
Query: 783 DLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGK 842
+ +R I+ L + E N + S + R +SA+ R K
Sbjct: 543 ETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV-------------------K 583
Query: 843 DKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAG 902
D EKE+ + E+ + TS ++ ++ KR ++KK E YK++ E EL +L
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKR----QIKKELEHYKEKGERAEELENELHHLEK 639
Query: 903 SNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPH 962
N E KK K E ++ Q+ +R + +KK + +T +L+ +++ +
Sbjct: 640 EN-ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLE--SLEKEN 696
Query: 963 DDKEEQDLDQQGNEENL 979
+E++L+ + N E+L
Sbjct: 697 SQLDEENLELRRNVESL 713
Score = 33.9 bits (76), Expect = 0.85
Identities = 79/360 (21%), Positives = 136/360 (37%), Gaps = 57/360 (15%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVEL-------MT 722
ER+ R + +++ + T +L S E E +S D+E E VE M
Sbjct: 669 ERENRKLKKTLDSFKNLTFQLESLEKE-------NSQLDEENLELRRNVESLKCASMKMA 721
Query: 723 QVDQEDITLQSGRDELNEELIQEESSEDEGEYEEV--------------------RKDQD 762
Q+ E+ L+S +++L + L ++S + E EV +K Q
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 763 SVGEMKDEGEETL----NYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSA 818
E++D E N + I L+ K +E S D K + +
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 819 KERREMKKKKLPSDSGDLEALEGKDKE--------KESTVHIETHQNTSKNVA--AVQPM 868
+++ E+K L ++ + LE ++K KES V ++ + +K + A +
Sbjct: 842 RQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDI 901
Query: 869 KRGQKSKMKKMKEKYKDQD-EEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQ 927
K + + EK K Q D E + L G NKE + ++ D+ K
Sbjct: 902 KTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKE---RLLHDEQSTDDRYKLLES 958
Query: 928 KPRGGQRVSDNIKKE-----TPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDS 982
K + S IK+E LE T+ Q + K + L Q+ +EE + S
Sbjct: 959 KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQS 1018
Score = 32.7 bits (73), Expect = 1.9
Identities = 38/231 (16%), Positives = 97/231 (41%), Gaps = 36/231 (15%)
Query: 302 KIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRA 361
K+ +++ K L+ EK+ LKK + K + E L+ + + ++ + ++ L+ ++
Sbjct: 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKK 778
Query: 362 IQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEED 421
IQ + S L ++ + + + ++ELK+ + + L + L +E
Sbjct: 779 IQQLESEL-------------QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETS 825
Query: 422 DDVDGDVNVEKNETEPPKGKKKKQKNKQLQK-------------PQKNKPLLVDVDLSLS 468
+EK++ + K K+ ++ +++ ++NK L ++ +
Sbjct: 826 -------QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE 878
Query: 469 AYANAKKYYDHKRYAAKKTQ---KTVEAAEKAFKSAEKKTKQTLKEVQTVT 516
+ K+ + K+ KT+ + S + KT+Q +++ +T
Sbjct: 879 SCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLT 929
Score = 31.6 bits (70), Expect = 4.2
Identities = 65/311 (20%), Positives = 134/311 (43%), Gaps = 22/311 (7%)
Query: 212 KVDEKLETKDIEKVLVSLQKAEDYMKTTSNFSGKGYIIQKREIKPCLEADKPVEDILTYE 271
++ + KDIEK L E +T+S S + +KR+IK LE K + E
Sbjct: 575 QISAEARVKDIEKENKILH--ESIKETSSKLSKIEF--EKRQIKKELEHYKEKGE--RAE 628
Query: 272 EFHPFLFSQHSQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHE 331
E L + ++ + + + KIE + + L++E + LKK + K+
Sbjct: 629 ELENELHHLEKENELLQKKITNLKIT--CEKIEALEQENSELERENRKLKKTLDSFKNLT 686
Query: 332 NRLEALQQAQEIDKLKGELIEMNLQIVD--------RAIQVVRSALANQIDWTEIGL-IV 382
+LE+L+ +E +L E +E+ + +Q+ L ++ + + GL ++
Sbjct: 687 FQLESLE--KENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL 744
Query: 383 KEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKK 442
K + + + + + + L ++ + L N ++ + ++ D+ +E N+T ++
Sbjct: 745 KASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ-DLEME-NQTLQKNLEE 802
Query: 443 KKQKNKQLQKPQK-NKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQKTVEAAEKAFKSA 501
K +K+L++ +K NK L + +K R A+ T+E +
Sbjct: 803 LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Query: 502 EKKTKQTLKEV 512
EK+ K KE+
Sbjct: 863 EKENKTLSKEI 873
Score = 30.8 bits (68), Expect = 7.2
Identities = 41/223 (18%), Positives = 99/223 (44%), Gaps = 18/223 (8%)
Query: 768 KDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLS---AKERREM 824
+DE ET+ D H P S +++ + +++SR+HLS A + ++
Sbjct: 204 RDEHSETIIELSEERDGLHFLPHASS---SAQSPCGSPGMKRTESRQHLSVELADAKAKI 260
Query: 825 KKKKLPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYK 884
++ + + + L+ K + ++ + ++ Q + N+ + R + ++ ++EK
Sbjct: 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAV 320
Query: 885 DQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETP 944
D+ + E+ S +E+ + K + E +K+ Q + + ++ + T
Sbjct: 321 RVDKLESEV---------SRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTR 371
Query: 945 FLEVITHELQDFAVD---DPHDDKEEQDLDQQGNEENLFDSLT 984
HEL+ + HD + E+D+D++ EE + +++T
Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMT 414
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 52.8 bits (125), Expect = 2e-06
Identities = 75/329 (22%), Positives = 133/329 (40%), Gaps = 34/329 (10%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
E KV + +ME + +E ++ M++ + E+KEE E E+ +
Sbjct: 459 ETKVEDEKSEMEEALTAITEELAVSMKE---EKKEAAEEKEEEPEAEEEEVAAKKSPVKA 515
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVG-------EMKDEGEETLNYPDTTI 782
T ++E E+ +E E+E E E + DQ G K+EGE+ +
Sbjct: 516 TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEA 575
Query: 783 DLSHLQP------QRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDL 836
+ + + +++A+KEE + + + + +K K P +
Sbjct: 576 EGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPV 635
Query: 837 EALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKK--MKEKYKDQDEED--RE 892
E +GK +S V + K+ P++ KS + K ++EK K + E
Sbjct: 636 EE-KGKSPVPKSPV-----EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 689
Query: 893 LIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHE 952
K G KEE+ K+ K+ K+E V+K+ +KP+ V + K E+P E E
Sbjct: 690 AKSKAEVGKGEQKEEEEKEVKEA-PKEEKVEKKEEKPKD---VPEKKKAESPVKEEAVAE 745
Query: 953 L----QDFAVDDPHDDKEEQDLDQQGNEE 977
+ + V + KEE QQ E+
Sbjct: 746 VVTITKSVKVHLEKETKEEGKPLQQEKEK 774
Score = 43.9 bits (102), Expect = 8e-04
Identities = 57/275 (20%), Positives = 116/275 (42%), Gaps = 29/275 (10%)
Query: 709 KEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMK 768
K +H+ E+ T+V+ E ++ + EEL E + EE K+++ E +
Sbjct: 447 KVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEE--KEEEPEAEEE 504
Query: 769 DEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKK 828
+ + T ++ + ++ ++ +EE +KS +++ +K++
Sbjct: 505 EVAAKKSPVKATAPEVKEEEGEKE-EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 563
Query: 829 LPSDSGDLEA-LEGKDKEKESTVHIETHQN---TSKNVAAVQPMKRGQKSKMKKMKEKYK 884
+ G+ EA EG++ E + +E T + + A +++ +K+K K
Sbjct: 564 GEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV- 622
Query: 885 DQDEEDRELIMKLLGSAGSNKEEKGKK-------GKKGKTKDEPVKKQPQKPRGGQRVSD 937
+E+ + + K S EEKGK +KGK+ PV K P + +G VS
Sbjct: 623 --EEKGKSPVPK------SPVEEKGKSPVPKSPVEEKGKS---PVPKSPVEEKGKSPVSK 671
Query: 938 N---IKKETPFLEVITHELQDFAVDDPHDDKEEQD 969
+ K ++P + E + A + KEE++
Sbjct: 672 SPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEE 706
Score = 42.4 bits (98), Expect = 0.002
Identities = 58/284 (20%), Positives = 113/284 (39%), Gaps = 31/284 (10%)
Query: 664 VWRHQGERKVRV-QDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMT 722
V +GE++ Q+E+ E S+ E + +G + ++EE ET E E
Sbjct: 520 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 579
Query: 723 QVDQEDITLQSGRDEL--NEELIQEESSED---------EGEYEEVRKDQDSVGEMKDEG 771
+E+ ++ +E+ EEL+ + E + EE K ++++G
Sbjct: 580 AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKG 639
Query: 772 EETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPS 831
+ + P+ +++ S + + K++S S E + K +
Sbjct: 640 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKG 699
Query: 832 DSGDLEALEGKDKEKESTVHI--ETHQNTSKNVAAVQPMKRGQKSKM------------K 877
+ + E E K+ KE V E ++ + A P+K +++ K
Sbjct: 700 EQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEK 759
Query: 878 KMKEKYKD-QDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDE 920
+ KE+ K Q E+++E G G ++EE KG KG K++
Sbjct: 760 ETKEEGKPLQQEKEKEKA----GGEGGSEEEGSDKGAKGSRKED 799
Score = 40.0 bits (92), Expect = 0.012
Identities = 52/232 (22%), Positives = 100/232 (43%), Gaps = 30/232 (12%)
Query: 712 HETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDE-GEYEEVRK--DQDSVGEMK 768
H P+ + Q + + + + EE+I+E EDE E EE ++ MK
Sbjct: 426 HRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMK 485
Query: 769 DEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKK 828
+E +E + +P+ +++A+K+ S + + + KE E ++++
Sbjct: 486 EEKKEAAEEKEE-------EPEAEEEEVAAKK--SPVKATAPEVKEEEGEKEEEEGQEEE 536
Query: 829 LPSDSG--DLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQ 886
D G +A EG +++ S+ E Q + A + G++++ K +EK ++
Sbjct: 537 EEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAE----GEEAEAK--EEKKVEE 590
Query: 887 DEEDRELIMKLLGSAGSNKEEKGKK-------GKKGKTKDEPVKKQPQKPRG 931
E+ +L+ A K EK K +KGK+ PV K P + +G
Sbjct: 591 KSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS---PVPKSPVEEKG 639
Score = 32.0 bits (71), Expect = 3.2
Identities = 49/246 (19%), Positives = 102/246 (41%), Gaps = 47/246 (19%)
Query: 677 DEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRD 736
D+++ L + T E+++ E Q+ +ED + E E + D E +D
Sbjct: 151 DQEIRELRA-TLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALRKD 209
Query: 737 ELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQR----- 791
L++ E + +V+ QD V ++ EE + I SH+ +R
Sbjct: 210 IEEASLVKVELDK------KVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLK 263
Query: 792 -----SIQKLASKEESSNS-----------------SDSKSQSRRHL-SAKERREMKKKK 828
+++++ S+ ES + +++ Q++ + SAKE +++
Sbjct: 264 TDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQ 323
Query: 829 LPSDSGDLEALEG---------KDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKM 879
L S S +LE++ G D E+ + ++Q+T + ++ RG K +M +
Sbjct: 324 LQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDT---IQQLENELRGTKWEMARH 380
Query: 880 KEKYKD 885
+Y+D
Sbjct: 381 LREYQD 386
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 52.8 bits (125), Expect = 2e-06
Identities = 75/329 (22%), Positives = 133/329 (40%), Gaps = 34/329 (10%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
E KV + +ME + +E ++ M++ + E+KEE E E+ +
Sbjct: 83 ETKVEDEKSEMEEALTAITEELAVSMKE---EKKEAAEEKEEEPEAEEEEVAAKKSPVKA 139
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVG-------EMKDEGEETLNYPDTTI 782
T ++E E+ +E E+E E E + DQ G K+EGE+ +
Sbjct: 140 TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEA 199
Query: 783 DLSHLQP------QRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDL 836
+ + + +++A+KEE + + + + +K K P +
Sbjct: 200 EGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPV 259
Query: 837 EALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKK--MKEKYKDQDEED--RE 892
E +GK +S V + K+ P++ KS + K ++EK K + E
Sbjct: 260 EE-KGKSPVPKSPV-----EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 313
Query: 893 LIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHE 952
K G KEE+ K+ K+ K+E V+K+ +KP+ V + K E+P E E
Sbjct: 314 AKSKAEVGKGEQKEEEEKEVKEA-PKEEKVEKKEEKPKD---VPEKKKAESPVKEEAVAE 369
Query: 953 L----QDFAVDDPHDDKEEQDLDQQGNEE 977
+ + V + KEE QQ E+
Sbjct: 370 VVTITKSVKVHLEKETKEEGKPLQQEKEK 398
Score = 43.9 bits (102), Expect = 8e-04
Identities = 57/275 (20%), Positives = 116/275 (42%), Gaps = 29/275 (10%)
Query: 709 KEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMK 768
K +H+ E+ T+V+ E ++ + EEL E + EE K+++ E +
Sbjct: 71 KVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEE--KEEEPEAEEE 128
Query: 769 DEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKK 828
+ + T ++ + ++ ++ +EE +KS +++ +K++
Sbjct: 129 EVAAKKSPVKATAPEVKEEEGEKE-EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 187
Query: 829 LPSDSGDLEA-LEGKDKEKESTVHIETHQN---TSKNVAAVQPMKRGQKSKMKKMKEKYK 884
+ G+ EA EG++ E + +E T + + A +++ +K+K K
Sbjct: 188 GEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV- 246
Query: 885 DQDEEDRELIMKLLGSAGSNKEEKGKK-------GKKGKTKDEPVKKQPQKPRGGQRVSD 937
+E+ + + K S EEKGK +KGK+ PV K P + +G VS
Sbjct: 247 --EEKGKSPVPK------SPVEEKGKSPVPKSPVEEKGKS---PVPKSPVEEKGKSPVSK 295
Query: 938 N---IKKETPFLEVITHELQDFAVDDPHDDKEEQD 969
+ K ++P + E + A + KEE++
Sbjct: 296 SPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEE 330
Score = 42.4 bits (98), Expect = 0.002
Identities = 58/284 (20%), Positives = 113/284 (39%), Gaps = 31/284 (10%)
Query: 664 VWRHQGERKVRV-QDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMT 722
V +GE++ Q+E+ E S+ E + +G + ++EE ET E E
Sbjct: 144 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 203
Query: 723 QVDQEDITLQSGRDEL--NEELIQEESSED---------EGEYEEVRKDQDSVGEMKDEG 771
+E+ ++ +E+ EEL+ + E + EE K ++++G
Sbjct: 204 AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKG 263
Query: 772 EETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPS 831
+ + P+ +++ S + + K++S S E + K +
Sbjct: 264 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKG 323
Query: 832 DSGDLEALEGKDKEKESTVHI--ETHQNTSKNVAAVQPMKRGQKSKM------------K 877
+ + E E K+ KE V E ++ + A P+K +++ K
Sbjct: 324 EQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEK 383
Query: 878 KMKEKYKD-QDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDE 920
+ KE+ K Q E+++E G G ++EE KG KG K++
Sbjct: 384 ETKEEGKPLQQEKEKEKA----GGEGGSEEEGSDKGAKGSRKED 423
Score = 40.0 bits (92), Expect = 0.012
Identities = 52/232 (22%), Positives = 100/232 (43%), Gaps = 30/232 (12%)
Query: 712 HETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDE-GEYEEVRK--DQDSVGEMK 768
H P+ + Q + + + + EE+I+E EDE E EE ++ MK
Sbjct: 50 HRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMK 109
Query: 769 DEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKK 828
+E +E + +P+ +++A+K+ S + + + KE E ++++
Sbjct: 110 EEKKEAAEEKEE-------EPEAEEEEVAAKK--SPVKATAPEVKEEEGEKEEEEGQEEE 160
Query: 829 LPSDSG--DLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQ 886
D G +A EG +++ S+ E Q + A + G++++ K +EK ++
Sbjct: 161 EEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAE----GEEAEAK--EEKKVEE 214
Query: 887 DEEDRELIMKLLGSAGSNKEEKGKK-------GKKGKTKDEPVKKQPQKPRG 931
E+ +L+ A K EK K +KGK+ PV K P + +G
Sbjct: 215 KSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS---PVPKSPVEEKG 263
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 52.8 bits (125), Expect = 2e-06
Identities = 53/257 (20%), Positives = 114/257 (44%), Gaps = 24/257 (9%)
Query: 736 DELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQK 795
D+ +E+++ E + + Y + E K E EE Y ++ Q Q + K
Sbjct: 169 DKRKKEMVKAEE-DTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFK 227
Query: 796 L---------ASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEK 846
L +KE +S + + + +R ++ + KKK+L + + +E + KEK
Sbjct: 228 LYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEK 287
Query: 847 ESTV------HIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGS 900
+S + +I+ +NTS + ++ K+ ++ K K++ D DE ++E++ +
Sbjct: 288 DSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS--VEK 345
Query: 901 AGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDD 960
A EE+ ++ + + +D +++ K R+ + K + EL+ F D
Sbjct: 346 ARQEFEERMEEESQSQGRDLTLEENQVKKY--HRLKEEASKRA---ATLAQELEKFN-RD 399
Query: 961 PHDDKEEQDLDQQGNEE 977
D++ DL+++ E
Sbjct: 400 QKADQDRLDLEERKKVE 416
Score = 49.7 bits (117), Expect = 1e-05
Identities = 45/264 (17%), Positives = 123/264 (46%), Gaps = 12/264 (4%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
+R +V+DE E + E +Q++ D + + + P ++ +
Sbjct: 254 KRMDKVEDELKEKKKELGKMM--REQQQIEKEIKEKDSELNQ-KRPQYIKAKENTSHKIK 310
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYP------DTTID 783
L++ + L Q+ + +G+ +E+ K+ SV + + E EE + D T++
Sbjct: 311 KLEAAKKSLQNA--QKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLE 368
Query: 784 LSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMK-KKKLPSDSGDLEALEGK 842
+ ++ +++ ASK ++ + + + +R + ++R +++ +KK+ +++ + L
Sbjct: 369 ENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREI 428
Query: 843 DKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAG 902
++ ++ +E + TSK Q G+ ++ +M ++ D+ ++ +M+ LG A
Sbjct: 429 EENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDAR 488
Query: 903 SNKEEKGKKGKKGKTKDEPVKKQP 926
+++E ++ +K + + + P
Sbjct: 489 IDRQESSRQQRKAEIMESIKRLYP 512
Score = 38.1 bits (87), Expect = 0.045
Identities = 41/162 (25%), Positives = 75/162 (46%), Gaps = 17/162 (10%)
Query: 400 KLQTNHVTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKPL 459
KL N V + N L S+ ++ + D ++ E +KKK+ K +++ Q+ +
Sbjct: 227 KLYHNEVEIEKLNKELASKNKEIEKD---KKRMDKVEDELKEKKKELGKMMREQQQIEKE 283
Query: 460 LVDVDLSLSA----YANAKKYYDHKRYAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTV 515
+ + D L+ Y AK+ HK + +K+++ A+K +K + + KE +
Sbjct: 284 IKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKE---M 340
Query: 516 TSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRY 557
S++KAR+ FE+ + S GRD E VK+Y
Sbjct: 341 LSVEKARQE--FEERMEEESQSQ-----GRDLTLEENQVKKY 375
Score = 37.4 bits (85), Expect = 0.077
Identities = 85/406 (20%), Positives = 151/406 (37%), Gaps = 84/406 (20%)
Query: 709 KEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMK 768
+E+ E L +V + + LQ + NE I++ + E + +E+ KD+ + +++
Sbjct: 201 QEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVE 260
Query: 769 DEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKK 828
DE +E L Q+ KE S+ + +++ AKE K KK
Sbjct: 261 DELKE---------KKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKK 311
Query: 829 LPS--------------DSGDLEALEGK--DKEKESTVHIETHQNTSKNVAAVQPMKRGQ 872
L + GD++ LE + EK E + S++ ++ Q
Sbjct: 312 LEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQ 371
Query: 873 KSKMKKMKEKYK-------------------DQDEEDRELIMKLLGSAGSNK-----EEK 908
K ++KE+ DQD D E K+ A + EE
Sbjct: 372 VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEEN 431
Query: 909 GKKGKKGK---TKDEPVKKQPQKPRG--------GQRVSDNIKKETPFLEVITHELQDFA 957
K+ +K + T + ++ +K G +R D I KE L + +L D
Sbjct: 432 QKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKE---LNQVMEQLGDAR 488
Query: 958 VDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTP 1017
+D Q+ +Q + + +S+ + +P V I +C P T KY++ +T
Sbjct: 489 ID-------RQESSRQQRKAEIMESIK-RLYPGSVYGRLIDLCQP----TQKKYQIAVTK 536
Query: 1018 GVQKKGKA-----AKTALNSFMHSKEATAREKDL----FRSVKDTD 1054
+ K A KT + + KE + + VK TD
Sbjct: 537 VLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTD 582
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 52.4 bits (124), Expect = 2e-06
Identities = 77/355 (21%), Positives = 136/355 (38%), Gaps = 31/355 (8%)
Query: 707 EDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGE 766
+DK E V E + +++ I +S + EE I++ E E + + S+G
Sbjct: 709 DDKSTKEKHVSKERNFKEERDKIKKESEKS-FREEKIKDLKEERENIPTDKDSEFTSLGM 767
Query: 767 MKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKK 826
E L+ + ID+ + K ++ S + R KE++ +
Sbjct: 768 SAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHE 827
Query: 827 KKLPSDSGDLEALEGKDKEKESTVHIETHQ-----NTSKNVAAVQPMKRGQKSKMKKMKE 881
K D DL K KEK+ T + SKN AA++ +KS+ K ++
Sbjct: 828 HKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRK 887
Query: 882 KYKDQDEEDREL-------IMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQR 934
K++ E++R L +M+ N E + K K KD + K+ +K R +
Sbjct: 888 HDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKK-EKSRDKES 946
Query: 935 VSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQ-DLDQQGNEENLF--DSLTGQPHPED 991
++ K I E + VD E+ L ++ +E L D +D
Sbjct: 947 INITNSKH------IQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKD 1000
Query: 992 VLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKTALNSFMHSKEATAREKDL 1046
+ Y +K K+++ ++ K +A K S SK+ +EK L
Sbjct: 1001 I--------DRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRL 1047
Score = 48.5 bits (114), Expect = 3e-05
Identities = 68/316 (21%), Positives = 136/316 (43%), Gaps = 57/316 (18%)
Query: 707 EDKEEH--ETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSV 764
E +E+H E+ + E +Q+ ++DI + E+ I+ E + KD+ +
Sbjct: 786 EKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSE--------KDKLDL 837
Query: 765 GEMKDEGEETLNYPDTTIDLSHLQPQRS-----IQKLASKEESSNSSD-----SKSQSRR 814
E D+ +E + H + ++S I+K +E+S D K + R
Sbjct: 838 SECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKER 897
Query: 815 HLS-AKERREMKKKKLPSDSGDLEALE-GKDKEKESTVHIETHQNTSKNV---------- 862
HL+ +KE+ M+KK SD+ + E GK+KEK+ + + +++
Sbjct: 898 HLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQE 957
Query: 863 ---AAVQPMKRGQKSKMKKMKEKYKDQ-----DEEDRELIMKLLGSAGSNKEEKGK---- 910
+++ + Q K +KEK KD+ D ++++ K + + K K
Sbjct: 958 EKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQIN 1017
Query: 911 -------KGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPHD 963
+ K K K P K +P+ + V+D++ +T F +++ L+D ++ H
Sbjct: 1018 SLLKLKSEADKPKPKSSPASKD-TRPKEKRLVNDDL-MQTSFERMLS--LKDLEIEQWH- 1072
Query: 964 DKEEQDLDQQGNEENL 979
K+ ++ +Q +E L
Sbjct: 1073 -KKHKEKIKQKEKERL 1087
Score = 48.1 bits (113), Expect = 4e-05
Identities = 61/266 (22%), Positives = 117/266 (43%), Gaps = 35/266 (13%)
Query: 679 DMETLASCTSELISEEMEQ--LDGGDTSSDEDKEEHETPVEVE---LMTQVDQEDITLQS 733
+ ++ SC + S+ + L+ G+ S+ + K+E +P + ++D+E TL+
Sbjct: 570 ESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKK 629
Query: 734 GRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGE-------ETLNYPDTTIDLSH 786
+ + E ++ E EGE E+ K +DS E++ E E D T DL
Sbjct: 630 HKLKHKEREKEKHKKEIEGEKEKY-KTKDSAKELQRSVEFDREFWKENFFKSDETEDLFL 688
Query: 787 LQPQRSIQKLASKEESSNSSDSKSQSRRHLSA----KERREMKKKKLPSDSGDLEALEGK 842
S+ + N D KS +H+S KE R+ K KK S E ++
Sbjct: 689 NMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERD-KIKKESEKSFREEKIKDL 747
Query: 843 DKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAG 902
+E+E+ + + TS ++A+ ++S + EK D +++++ +
Sbjct: 748 KEERENIPTDKDSEFTSLGMSAI------EESIGLHLVEKEIDIEKQEKHI--------- 792
Query: 903 SNKEEKGKKGKKGKTKDEPVKKQPQK 928
KE K K K+ + K++ ++K +K
Sbjct: 793 --KESKEKPEKRSQIKEKDIEKMERK 816
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/186 (25%), Positives = 76/186 (40%), Gaps = 10/186 (5%)
Query: 801 ESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKESTVH---IETHQN 857
E S++K + H E + KK+ + L+ + K KE+E H IE +
Sbjct: 592 EFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKE 651
Query: 858 TSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE-EDRELIMKLLGSAGSNKEEKGKKGKKGK 916
K + + ++R + + KE + DE ED L M+ E+K K K K
Sbjct: 652 KYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNME---HESLTLEKKSKLEKNIK 708
Query: 917 TKDEPVKKQPQKPRGGQRVSDNIKKET--PFLEVITHELQDFAVDDPHD-DKEEQDLDQQ 973
+K K R + D IKKE+ F E +L++ + P D D E L
Sbjct: 709 DDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMS 768
Query: 974 GNEENL 979
EE++
Sbjct: 769 AIEESI 774
Score = 34.3 bits (77), Expect = 0.65
Identities = 46/230 (20%), Positives = 95/230 (41%), Gaps = 25/230 (10%)
Query: 676 QDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGR 735
+ D E++ S+ I EE + + D +K +HE P+ ++ T+ E + G+
Sbjct: 940 KSRDKESINITNSKHIQEEKKS-----SIVDGNKAQHEKPLSLKEKTK--DEPLKTPDGK 992
Query: 736 DELNEELIQEESSEDEGEYEEVRKDQDSV---GEMKDEGEETLNYPDTTIDLSHLQPQRS 792
++ ++ +D Y+E K +D + +K + E P ++ +P+
Sbjct: 993 EK-------DKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPK-- 1043
Query: 793 IQKLASKEESSNSSDSKSQSRRHLSA----KERREMKKKKLPSDSGDLEALEGKDKEKES 848
+K ++ +S + S + L K+ +E K+K + LE K K+KE
Sbjct: 1044 -EKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEK 1102
Query: 849 TVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEE-DRELIMKL 897
T H T + + +K K+ K+ ++ + D + +M L
Sbjct: 1103 TKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTL 1152
Score = 31.6 bits (70), Expect = 4.2
Identities = 32/151 (21%), Positives = 62/151 (41%), Gaps = 3/151 (1%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
+ K V D+ M+T L E+EQ + KE+ L ++ ++
Sbjct: 1043 KEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEK 1102
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQP 789
T + + N+EL + +SSE Y + ++ +D+V + + +T N T+ S
Sbjct: 1103 TKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSN-RSQSVDTKNV--MTLGKSSFVS 1159
Query: 790 QRSIQKLASKEESSNSSDSKSQSRRHLSAKE 820
S+ + E S+S S +++ E
Sbjct: 1160 DNSLNRSPRSENEKPGLSSRSVSMISVASSE 1190
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 52.4 bits (124), Expect = 2e-06
Identities = 77/355 (21%), Positives = 136/355 (38%), Gaps = 31/355 (8%)
Query: 707 EDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGE 766
+DK E V E + +++ I +S + EE I++ E E + + S+G
Sbjct: 732 DDKSTKEKHVSKERNFKEERDKIKKESEKS-FREEKIKDLKEERENIPTDKDSEFTSLGM 790
Query: 767 MKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKK 826
E L+ + ID+ + K ++ S + R KE++ +
Sbjct: 791 SAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHE 850
Query: 827 KKLPSDSGDLEALEGKDKEKESTVHIETHQ-----NTSKNVAAVQPMKRGQKSKMKKMKE 881
K D DL K KEK+ T + SKN AA++ +KS+ K ++
Sbjct: 851 HKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRK 910
Query: 882 KYKDQDEEDREL-------IMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQR 934
K++ E++R L +M+ N E + K K KD + K+ +K R +
Sbjct: 911 HDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKK-EKSRDKES 969
Query: 935 VSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQ-DLDQQGNEENLF--DSLTGQPHPED 991
++ K I E + VD E+ L ++ +E L D +D
Sbjct: 970 INITNSKH------IQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKD 1023
Query: 992 VLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKTALNSFMHSKEATAREKDL 1046
+ Y +K K+++ ++ K +A K S SK+ +EK L
Sbjct: 1024 I--------DRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRL 1070
Score = 48.5 bits (114), Expect = 3e-05
Identities = 68/316 (21%), Positives = 136/316 (43%), Gaps = 57/316 (18%)
Query: 707 EDKEEH--ETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSV 764
E +E+H E+ + E +Q+ ++DI + E+ I+ E + KD+ +
Sbjct: 809 EKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSE--------KDKLDL 860
Query: 765 GEMKDEGEETLNYPDTTIDLSHLQPQRS-----IQKLASKEESSNSSD-----SKSQSRR 814
E D+ +E + H + ++S I+K +E+S D K + R
Sbjct: 861 SECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKER 920
Query: 815 HLS-AKERREMKKKKLPSDSGDLEALE-GKDKEKESTVHIETHQNTSKNV---------- 862
HL+ +KE+ M+KK SD+ + E GK+KEK+ + + +++
Sbjct: 921 HLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQE 980
Query: 863 ---AAVQPMKRGQKSKMKKMKEKYKDQ-----DEEDRELIMKLLGSAGSNKEEKGK---- 910
+++ + Q K +KEK KD+ D ++++ K + + K K
Sbjct: 981 EKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQIN 1040
Query: 911 -------KGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPHD 963
+ K K K P K +P+ + V+D++ +T F +++ L+D ++ H
Sbjct: 1041 SLLKLKSEADKPKPKSSPASKD-TRPKEKRLVNDDL-MQTSFERMLS--LKDLEIEQWH- 1095
Query: 964 DKEEQDLDQQGNEENL 979
K+ ++ +Q +E L
Sbjct: 1096 -KKHKEKIKQKEKERL 1110
Score = 48.1 bits (113), Expect = 4e-05
Identities = 61/266 (22%), Positives = 117/266 (43%), Gaps = 35/266 (13%)
Query: 679 DMETLASCTSELISEEMEQ--LDGGDTSSDEDKEEHETPVEVE---LMTQVDQEDITLQS 733
+ ++ SC + S+ + L+ G+ S+ + K+E +P + ++D+E TL+
Sbjct: 593 ESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKK 652
Query: 734 GRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGE-------ETLNYPDTTIDLSH 786
+ + E ++ E EGE E+ K +DS E++ E E D T DL
Sbjct: 653 HKLKHKEREKEKHKKEIEGEKEKY-KTKDSAKELQRSVEFDREFWKENFFKSDETEDLFL 711
Query: 787 LQPQRSIQKLASKEESSNSSDSKSQSRRHLSA----KERREMKKKKLPSDSGDLEALEGK 842
S+ + N D KS +H+S KE R+ K KK S E ++
Sbjct: 712 NMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERD-KIKKESEKSFREEKIKDL 770
Query: 843 DKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAG 902
+E+E+ + + TS ++A+ ++S + EK D +++++ +
Sbjct: 771 KEERENIPTDKDSEFTSLGMSAI------EESIGLHLVEKEIDIEKQEKHI--------- 815
Query: 903 SNKEEKGKKGKKGKTKDEPVKKQPQK 928
KE K K K+ + K++ ++K +K
Sbjct: 816 --KESKEKPEKRSQIKEKDIEKMERK 839
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/186 (25%), Positives = 76/186 (40%), Gaps = 10/186 (5%)
Query: 801 ESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKESTVH---IETHQN 857
E S++K + H E + KK+ + L+ + K KE+E H IE +
Sbjct: 615 EFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKE 674
Query: 858 TSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE-EDRELIMKLLGSAGSNKEEKGKKGKKGK 916
K + + ++R + + KE + DE ED L M+ E+K K K K
Sbjct: 675 KYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNME---HESLTLEKKSKLEKNIK 731
Query: 917 TKDEPVKKQPQKPRGGQRVSDNIKKET--PFLEVITHELQDFAVDDPHD-DKEEQDLDQQ 973
+K K R + D IKKE+ F E +L++ + P D D E L
Sbjct: 732 DDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMS 791
Query: 974 GNEENL 979
EE++
Sbjct: 792 AIEESI 797
Score = 34.3 bits (77), Expect = 0.65
Identities = 46/230 (20%), Positives = 95/230 (41%), Gaps = 25/230 (10%)
Query: 676 QDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQSGR 735
+ D E++ S+ I EE + + D +K +HE P+ ++ T+ E + G+
Sbjct: 963 KSRDKESINITNSKHIQEEKKS-----SIVDGNKAQHEKPLSLKEKTK--DEPLKTPDGK 1015
Query: 736 DELNEELIQEESSEDEGEYEEVRKDQDSV---GEMKDEGEETLNYPDTTIDLSHLQPQRS 792
++ ++ +D Y+E K +D + +K + E P ++ +P+
Sbjct: 1016 EK-------DKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPK-- 1066
Query: 793 IQKLASKEESSNSSDSKSQSRRHLSA----KERREMKKKKLPSDSGDLEALEGKDKEKES 848
+K ++ +S + S + L K+ +E K+K + LE K K+KE
Sbjct: 1067 -EKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEK 1125
Query: 849 TVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEE-DRELIMKL 897
T H T + + +K K+ K+ ++ + D + +M L
Sbjct: 1126 TKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTL 1175
Score = 31.6 bits (70), Expect = 4.2
Identities = 32/151 (21%), Positives = 62/151 (41%), Gaps = 3/151 (1%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
+ K V D+ M+T L E+EQ + KE+ L ++ ++
Sbjct: 1066 KEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEK 1125
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQP 789
T + + N+EL + +SSE Y + ++ +D+V + + +T N T+ S
Sbjct: 1126 TKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSN-RSQSVDTKNV--MTLGKSSFVS 1182
Query: 790 QRSIQKLASKEESSNSSDSKSQSRRHLSAKE 820
S+ + E S+S S +++ E
Sbjct: 1183 DNSLNRSPRSENEKPGLSSRSVSMISVASSE 1213
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 52.0 bits (123), Expect = 3e-06
Identities = 55/244 (22%), Positives = 100/244 (40%), Gaps = 15/244 (6%)
Query: 739 NEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLAS 798
N++ QEE S +++ G D G ++ + + H S + +
Sbjct: 4 NKDKSQEEDSSLHSNASSHSASEEASGS--DSGSQSESEQGSDPGSGHGSESNSSSESSE 61
Query: 799 KEESSNSSDSKSQSRRHL-SAKERREMKK------KKLPSDSGDLEALEGKDKEKESTVH 851
+ S S + S+S+ L AKE+ KK KK+ + D+ + ++ ++
Sbjct: 62 SQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSR 121
Query: 852 IETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKK 911
+ S + P +RGQ+ K+ EK+K + ED + S K+ K ++
Sbjct: 122 FNIKEEASSGSESGSPKRRGQRQLKKQ--EKWKQEPSEDEQEQGTSAESEPEQKKVKARR 179
Query: 912 GKKGKTKDEP-VKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFA---VDDPHDDKEE 967
+T +P VKKQP+ RG ++ D+ ++ E + + A V DD E
Sbjct: 180 PVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFE 239
Query: 968 QDLD 971
D D
Sbjct: 240 TDSD 243
Score = 41.2 bits (95), Expect = 0.005
Identities = 46/225 (20%), Positives = 92/225 (40%), Gaps = 17/225 (7%)
Query: 672 KVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEE----HETPVEVELMTQVDQE 727
K + Q+ED ++ +S SEE D G S E + H + + Q
Sbjct: 5 KDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQS 64
Query: 728 DITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHL 787
+ +S + L + + E+ ++ + ++K EE YPD
Sbjct: 65 ESESESAGSKSQPVLPEAK--------EKPASKKERIADVKKMWEE---YPDVYGVRRSN 113
Query: 788 QPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKE 847
+ ++ + KEE+S+ S+S S RR +++E K K+ PS+ + + + ++
Sbjct: 114 RSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQE-KWKQEPSEDEQEQGTSAESEPEQ 172
Query: 848 STVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRE 892
V + V + K+ + + K+ K+ D+D++D E
Sbjct: 173 KKVKAR-RPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDE 216
Score = 39.7 bits (91), Expect = 0.015
Identities = 55/238 (23%), Positives = 92/238 (38%), Gaps = 58/238 (24%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDI 729
E + Q + ++T A +L+ + +E+ G T +E K + P +V +E+
Sbjct: 1300 ETDKKPQGKQLQTRADYLLKLLRKGLEK-KGAVTGGEEAKLKKRKP-------RVKKEN- 1350
Query: 730 TLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQP 789
+ ++E EL S++ E GE+KD+G E P
Sbjct: 1351 KVPRLKEEHGIELSSPRHSDNPSEE----------GEVKDDGLEK-------------SP 1387
Query: 790 QRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKEST 849
+ QK KE N S + KER++ K KK SGD ++ K K +
Sbjct: 1388 MKKKQK--KKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKS-SSKSKRSQGP 1444
Query: 850 VHIETHQNTSKNVAAVQPMKRGQ--------------KSKMKKMKEKYKDQDEEDREL 893
VHI A +P+ G+ K +M+ +K+ K D+ D+ L
Sbjct: 1445 VHI---------TAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGL 1493
Score = 35.8 bits (81), Expect = 0.22
Identities = 27/102 (26%), Positives = 53/102 (51%), Gaps = 18/102 (17%)
Query: 872 QKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRG 931
+KS MKK ++K ++++ +++++ S K+++G K +K K+KD+ +KP+
Sbjct: 1384 EKSPMKKKQKKKENKENKEKQM--------SSRKDKEGDKERK-KSKDKK-----EKPKS 1429
Query: 932 GQRVSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQ 973
G S + K + IT + + + DD DLDQ+
Sbjct: 1430 GDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDD----DLDQE 1467
Score = 32.7 bits (73), Expect = 1.9
Identities = 37/162 (22%), Positives = 65/162 (40%), Gaps = 25/162 (15%)
Query: 383 KEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEEDDDVDGDV-NVEKNETEPPKGK 441
KE GD +S+ + H+T P + E+EDDD+D + ++ K P
Sbjct: 1424 KEKPKSGDAKSSSKSKRSQGPVHITAG-SEPVPIGEDEDDDLDQETFSICKERMRP---- 1478
Query: 442 KKKQKNKQLQKPQKNKPLLVDVDLS--------------LSAYANAKKYYDHKR----YA 483
K+ KQL KP K + ++ + L AY++ + +R +
Sbjct: 1479 -VKKALKQLDKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFV 1537
Query: 484 AKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVY 525
+K T+ K +K A KK Q +E + + +K +
Sbjct: 1538 SKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDVTGGKKPF 1579
Score = 31.2 bits (69), Expect = 5.5
Identities = 30/129 (23%), Positives = 56/129 (43%), Gaps = 6/129 (4%)
Query: 707 EDKEEHETPVEVELMTQVDQEDITLQSGRDELNEE--LIQEESSEDEGEYEE-VRKDQDS 763
E+ E E ++ L +E+ S DEL + + + EDE E EE KD D
Sbjct: 986 EESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDE 1045
Query: 764 VGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERRE 823
+ + +E + + + +L + I+ ++K+ +N SDS ++S+R E
Sbjct: 1046 I--IPEEQRKKVEEEERQKELEEIYMLPRIRS-STKKAQTNDSDSDTESKRQAQRSSASE 1102
Query: 824 MKKKKLPSD 832
+ + D
Sbjct: 1103 SETEDSDDD 1111
>gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2
[Homo sapiens]
Length = 501
Score = 52.0 bits (123), Expect = 3e-06
Identities = 55/244 (22%), Positives = 100/244 (40%), Gaps = 15/244 (6%)
Query: 739 NEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLAS 798
N++ QEE S +++ G D G ++ + + H S + +
Sbjct: 4 NKDKSQEEDSSLHSNASSHSASEEASGS--DSGSQSESEQGSDPGSGHGSESNSSSESSE 61
Query: 799 KEESSNSSDSKSQSRRHL-SAKERREMKK------KKLPSDSGDLEALEGKDKEKESTVH 851
+ S S + S+S+ L AKE+ KK KK+ + D+ + ++ ++
Sbjct: 62 SQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSR 121
Query: 852 IETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKK 911
+ S + P +RGQ+ K+ EK+K + ED + S K+ K ++
Sbjct: 122 FNIKEEASSGSESGSPKRRGQRQLKKQ--EKWKQEPSEDEQEQGTSAESEPEQKKVKARR 179
Query: 912 GKKGKTKDEP-VKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFA---VDDPHDDKEE 967
+T +P VKKQP+ RG ++ D+ ++ E + + A V DD E
Sbjct: 180 PVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFE 239
Query: 968 QDLD 971
D D
Sbjct: 240 TDSD 243
Score = 41.2 bits (95), Expect = 0.005
Identities = 46/225 (20%), Positives = 92/225 (40%), Gaps = 17/225 (7%)
Query: 672 KVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEE----HETPVEVELMTQVDQE 727
K + Q+ED ++ +S SEE D G S E + H + + Q
Sbjct: 5 KDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQS 64
Query: 728 DITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHL 787
+ +S + L + + E+ ++ + ++K EE YPD
Sbjct: 65 ESESESAGSKSQPVLPEAK--------EKPASKKERIADVKKMWEE---YPDVYGVRRSN 113
Query: 788 QPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKE 847
+ ++ + KEE+S+ S+S S RR +++E K K+ PS+ + + + ++
Sbjct: 114 RSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQE-KWKQEPSEDEQEQGTSAESEPEQ 172
Query: 848 STVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRE 892
V + V + K+ + + K+ K+ D+D++D E
Sbjct: 173 KKVKAR-RPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDE 216
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 51.2 bits (121), Expect = 5e-06
Identities = 65/322 (20%), Positives = 139/322 (43%), Gaps = 38/322 (11%)
Query: 666 RHQGERKVRVQDEDM----ETLASCTSELIS-EEMEQLDGGDTSSDEDKEEHETPVEVEL 720
+H E KV+ E+M ET+A T E + +E Q D ++EDK T +++L
Sbjct: 974 KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033
Query: 721 MTQVDQEDITLQS----------------GRDELNEELIQEESSEDEGEYEEVRKDQDSV 764
QVD + +L+ G +L +E I + +E + E+++K + +
Sbjct: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
Query: 765 GEM--KDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERR 822
+ K E E+ L + + Q I++L + E+ +S +K++ +R ++E
Sbjct: 1094 SNLQSKIEDEQALGIQ---LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Query: 823 EMKKKKLPSDSGDLEALEGKDKEK-----------ESTVHIETHQNTSKNVAAVQPMKRG 871
E+ ++ + +E K + E+T+ E T + A + G
Sbjct: 1151 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG 1210
Query: 872 QK-SKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPR 930
++ ++++K+K + + E + I L + + + KG K +T ++ + + K
Sbjct: 1211 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEE 1270
Query: 931 GGQRVSDNIKKETPFLEVITHE 952
QR+ +++ + L+ + E
Sbjct: 1271 EQQRLINDLTAQRGRLQTESGE 1292
Score = 42.4 bits (98), Expect = 0.002
Identities = 70/326 (21%), Positives = 142/326 (43%), Gaps = 38/326 (11%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGG------DTSSDEDKEEHETPVEVELMTQ 723
ER R + D++ LA + I E +QLD + S+ + K E E + ++L +
Sbjct: 1055 ERAKRKLEGDLK-LAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKK 1113
Query: 724 VDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTID 783
+ + LQ+ +EL EE+ E +S + E + ++ + E+ + EE I+
Sbjct: 1114 IKE----LQARIEELEEEIEAERASRAKAEKQRSDLSRE-LEEISERLEEAGGATSAQIE 1168
Query: 784 LSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKD 843
++ + + EE++ ++ + + R A E+ ++ +L+ ++ K
Sbjct: 1169 MNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQ-----IDNLQRVKQKL 1223
Query: 844 KEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKE----KYKDQDEEDRELIMKLLG 899
++++S + +E + + NV V K G KM + E + K ++EE + LI L
Sbjct: 1224 EKEKSEMKMEI-DDLASNVETVSKAK-GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTA 1281
Query: 900 SAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLE-------VITHE 952
G + E G+ ++ K+ V Q RG Q + I++ LE + H
Sbjct: 1282 QRGRLQTESGEFSRQLDEKEALVS---QLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
Query: 953 LQDFAVD-----DPHDDKEEQDLDQQ 973
LQ D + +++++E + Q
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQ 1364
Score = 37.7 bits (86), Expect = 0.059
Identities = 48/254 (18%), Positives = 115/254 (45%), Gaps = 20/254 (7%)
Query: 291 SFDKAVDEFYSKIEGQKIDLKALQQEKQAL-KKLDNVRKDHENRLEALQQAQEIDK-LKG 348
+FDK + E+ K E +L+A Q+E ++L +L ++ +E L+ L+ + +K L+
Sbjct: 1454 NFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513
Query: 349 ELIEMNLQIVD---RAIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNH 405
E+ ++ QI + R ++ + + + E+ ++EA+A + I ++L+ N
Sbjct: 1514 EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573
Query: 406 VTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKPLLVDVDL 465
V + +EE D + + + + + +N ++ +K + L ++++
Sbjct: 1574 VKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633
Query: 466 SLS----AYANAKKYYDHKRYAAKKTQ-------KTVEAAEKAFKSAEKKTKQTLKEVQ- 513
L+ A A + Y + + K TQ ++ E ++ E++ E++
Sbjct: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693
Query: 514 ---TVTSIQKARKV 524
T+ +++RK+
Sbjct: 1694 LRATLEQTERSRKI 1707
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 51.2 bits (121), Expect = 5e-06
Identities = 65/322 (20%), Positives = 139/322 (43%), Gaps = 38/322 (11%)
Query: 666 RHQGERKVRVQDEDM----ETLASCTSELIS-EEMEQLDGGDTSSDEDKEEHETPVEVEL 720
+H E KV+ E+M ET+A T E + +E Q D ++EDK T +++L
Sbjct: 974 KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKL 1033
Query: 721 MTQVDQEDITLQS----------------GRDELNEELIQEESSEDEGEYEEVRKDQDSV 764
QVD + +L+ G +L +E I + +E + E+++K + +
Sbjct: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
Query: 765 GEM--KDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERR 822
+ K E E+ L + + Q I++L + E+ +S +K++ +R ++E
Sbjct: 1094 SNLQSKIEDEQALGIQ---LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Query: 823 EMKKKKLPSDSGDLEALEGKDKEK-----------ESTVHIETHQNTSKNVAAVQPMKRG 871
E+ ++ + +E K + E+T+ E T + A + G
Sbjct: 1151 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG 1210
Query: 872 QK-SKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPR 930
++ ++++K+K + + E + I L + + + KG K +T ++ + + K
Sbjct: 1211 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEE 1270
Query: 931 GGQRVSDNIKKETPFLEVITHE 952
QR+ +++ + L+ + E
Sbjct: 1271 EQQRLINDLTAQRGRLQTESGE 1292
Score = 42.4 bits (98), Expect = 0.002
Identities = 70/326 (21%), Positives = 142/326 (43%), Gaps = 38/326 (11%)
Query: 670 ERKVRVQDEDMETLASCTSELISEEMEQLDGG------DTSSDEDKEEHETPVEVELMTQ 723
ER R + D++ LA + I E +QLD + S+ + K E E + ++L +
Sbjct: 1055 ERAKRKLEGDLK-LAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKK 1113
Query: 724 VDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTID 783
+ + LQ+ +EL EE+ E +S + E + ++ + E+ + EE I+
Sbjct: 1114 IKE----LQARIEELEEEIEAERASRAKAEKQRSDLSRE-LEEISERLEEAGGATSAQIE 1168
Query: 784 LSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKD 843
++ + + EE++ ++ + + R A E+ ++ +L+ ++ K
Sbjct: 1169 MNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQ-----IDNLQRVKQKL 1223
Query: 844 KEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKE----KYKDQDEEDRELIMKLLG 899
++++S + +E + + NV V K G KM + E + K ++EE + LI L
Sbjct: 1224 EKEKSEMKMEI-DDLASNVETVSKAK-GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTA 1281
Query: 900 SAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLE-------VITHE 952
G + E G+ ++ K+ V Q RG Q + I++ LE + H
Sbjct: 1282 QRGRLQTESGEFSRQLDEKEALVS---QLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
Query: 953 LQDFAVD-----DPHDDKEEQDLDQQ 973
LQ D + +++++E + Q
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQ 1364
Score = 37.7 bits (86), Expect = 0.059
Identities = 48/254 (18%), Positives = 115/254 (45%), Gaps = 20/254 (7%)
Query: 291 SFDKAVDEFYSKIEGQKIDLKALQQEKQAL-KKLDNVRKDHENRLEALQQAQEIDK-LKG 348
+FDK + E+ K E +L+A Q+E ++L +L ++ +E L+ L+ + +K L+
Sbjct: 1454 NFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513
Query: 349 ELIEMNLQIVD---RAIQVVRSALANQIDWTEIGLIVKEAQAQGDPVASAIKELKLQTNH 405
E+ ++ QI + R ++ + + + E+ ++EA+A + I ++L+ N
Sbjct: 1514 EISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573
Query: 406 VTMLLRNPYLLSEEEDDDVDGDVNVEKNETEPPKGKKKKQKNKQLQKPQKNKPLLVDVDL 465
V + +EE D + + + + + +N ++ +K + L ++++
Sbjct: 1574 VKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI 1633
Query: 466 SLS----AYANAKKYYDHKRYAAKKTQ-------KTVEAAEKAFKSAEKKTKQTLKEVQ- 513
L+ A A + Y + + K TQ ++ E ++ E++ E++
Sbjct: 1634 QLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEE 1693
Query: 514 ---TVTSIQKARKV 524
T+ +++RK+
Sbjct: 1694 LRATLEQTERSRKI 1707
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 51.2 bits (121), Expect = 5e-06
Identities = 75/361 (20%), Positives = 141/361 (39%), Gaps = 48/361 (13%)
Query: 667 HQGERKVRVQDEDMET-----LASCTSELISEEMEQLD-----GGDTSSDEDKEEHETPV 716
H GE + + +D++ L +L EE ++LD D DE++E+++T
Sbjct: 4738 HDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEE 4797
Query: 717 EVELMTQVDQE----DITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGE 772
M + D E D L SG ++ ++ ++E E ++ + +D + E DE +
Sbjct: 4798 TGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERD 4857
Query: 773 -------------------ETLNYP-DTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQS 812
E L+ P D +D +EE+ K +
Sbjct: 4858 YDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEE 4917
Query: 813 RRHLSAKERREMKKKKLPSDSGDLEALEG--KDKEKESTVHIETHQNTSKNVAAVQPMKR 870
H A+ER E + + S S E EG +D + E ++T + AA P +
Sbjct: 4918 AGH-EAEERGETETDQNESQSPQ-EPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEH 4975
Query: 871 GQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPR 930
++ + + ++EK K+ DEE E G A + + ++ ++ +E V + ++
Sbjct: 4976 SEE-QQQSVEEKDKEADEEGGE-----NGPADQGFQPQEEEEREDSDTEEQVPEALERKE 5029
Query: 931 G---GQRVSDNIKKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQP 987
GQ +N+ + T +E+ + + H +G+E N L Q
Sbjct: 5030 HASCGQTGVENM-QNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQK 5088
Query: 988 H 988
H
Sbjct: 5089 H 5089
Score = 46.2 bits (108), Expect = 2e-04
Identities = 64/313 (20%), Positives = 115/313 (36%), Gaps = 47/313 (15%)
Query: 692 SEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITL-----QSGRDELNEELIQEE 746
+E E++D G D D +H E V+++D ++G + + +EE
Sbjct: 4951 AEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEE 5010
Query: 747 SSEDEGEYEEV-----RKDQDSVGEM-------------------KDEGEETLNYPDTTI 782
ED E+V RK+ S G+ K++G+E
Sbjct: 5011 EREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADA 5070
Query: 783 DLSHLQPQRSIQKLASKEESSNSSDS----KSQSRRHLSAKERREMKKKKLPSDSGDLEA 838
+ + I +LAS++ + ++ S Q+ S + E K+L + D A
Sbjct: 5071 NQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHA 5130
Query: 839 LEGKDKEKESTVHIET---HQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIM 895
+G ++ ++ V H + Q K + + K+ KDQ+EE+ E +
Sbjct: 5131 EQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTL 5190
Query: 896 KLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQD 955
+ ++E+ K + K E +K P G + E V T E QD
Sbjct: 5191 -----MDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEM------EVEIQTVKTEEDQD 5239
Query: 956 FAVDDPHDDKEEQ 968
D H + E +
Sbjct: 5240 PRTDKAHKETENE 5252
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 50.8 bits (120), Expect = 7e-06
Identities = 69/323 (21%), Positives = 129/323 (39%), Gaps = 57/323 (17%)
Query: 660 DESCVWRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVE 719
D S R + E+K ED T++ ++ GG ++E K +
Sbjct: 10 DCSAEAREKMEQKEGKLSEDGTTVSPAADN------PEMSGGGAPAEETKGTAGKAINEG 63
Query: 720 LMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRK---DQDSVGEMKDEGEETLN 776
T+ +++ D ++ EL E + DE + E R+ +D+ E+K E E
Sbjct: 64 PPTESGKQEKA--PAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEK-- 119
Query: 777 YPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDL 836
+TT+ Q++ ++E + S +++ + A E+++ ++K+ +SG
Sbjct: 120 -EETTV---------GSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQK 169
Query: 837 EALEGKDK-EKESTVHIETHQNTSKNVAAVQPMKRGQKSKMK-KMKEKYKDQDEEDRELI 894
+DK E ++TV E + S+ + GQ+ + + KEK D
Sbjct: 170 ADANDRDKPEPKATVEEEDAKTASQE-------ETGQRKECSTEPKEKATD--------- 213
Query: 895 MKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQ 954
EE + +K +DE K +P++P G + K+E E E +
Sbjct: 214 -----------EEAKAESQKAVVEDE-AKAEPKEPDGKEEAKHGAKEEADAKE----EAE 257
Query: 955 DFAVDDPHDDKEEQDLDQQGNEE 977
D +P EEQ+ D + E
Sbjct: 258 DAEEAEPGSPSEEQEQDVEKEPE 280
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 50.4 bits (119), Expect = 9e-06
Identities = 55/277 (19%), Positives = 118/277 (42%), Gaps = 50/277 (18%)
Query: 672 KVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITL 731
K + +E+++T A +E E + + D + + + + + E P + + +V +E+I
Sbjct: 48 KSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIED 107
Query: 732 QSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQR 791
+ + +E + E +E + +E +DQ+ E + G+E +
Sbjct: 108 ATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNE--EKGEAGKEDKD--------------- 150
Query: 792 SIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKESTVH 851
++ + + K+ + + AKE+ + KK + +G+ +G+D+++E
Sbjct: 151 -------EKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEE---- 199
Query: 852 IETHQNTSKNVAAVQPMKRGQKSKMKKMK----EKYKDQDEEDRELIMKLLGSAGSNKEE 907
E + T ++G K + K +K EK ++ +ED G N+EE
Sbjct: 200 -EDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE----------GGNEEE 248
Query: 908 KGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETP 944
GK+ + K ++E ++ K D+ KKE P
Sbjct: 249 AGKEKEDLKEEEEGKEEDEIK-------EDDGKKEEP 278
Score = 39.7 bits (91), Expect = 0.015
Identities = 41/191 (21%), Positives = 84/191 (43%), Gaps = 19/191 (9%)
Query: 673 VRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQVDQEDITLQ 732
V V++E++E +E E+ E + + +ED++E E E + +ED +
Sbjct: 98 VEVKEENIED----ATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEE-KGEAGKEDKD-E 151
Query: 733 SGRDELNEELIQEESSEDEGEYEEVRKDQDSVG---EMKDEGEETLNYPDT--------T 781
G ++ E+ E ED E E+ +K +D G + K++GE+ D
Sbjct: 152 KGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKEN 211
Query: 782 IDLSHLQPQRSIQKLASKEESSNSSDSKSQS--RRHLSAKERREMKKKKLPSDSGDLEAL 839
D ++ + + KE+ D K + KE+ ++K+++ + +++
Sbjct: 212 EDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKED 271
Query: 840 EGKDKEKESTV 850
+GK +E +S V
Sbjct: 272 DGKKEEPQSIV 282
Score = 35.4 bits (80), Expect = 0.29
Identities = 46/217 (21%), Positives = 85/217 (39%), Gaps = 29/217 (13%)
Query: 789 PQRSIQKLASKEESSNSSDSKSQSRRHLSAKERREMKKKKLPSDSGDLEALEGKDKEKES 848
P+ ++ +S + SD ++ SA+ E K++ + + + A G+ K E+
Sbjct: 32 PEVKPKRTSSSRKMKTKSDMMEENI-DTSAQAVAETKQEAVVEEDYNENAKNGEAKITEA 90
Query: 849 TVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDE-EDRELIMKLLGSAGSNK-- 905
+ + K G+K + + K +++D+ ED E + G AG
Sbjct: 91 PASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKD 150
Query: 906 ---EEKGKKGKKGKTKDEPVKKQPQKPRG---------GQRVSDNIKKETPFLEV----- 948
EE GK+ K G K E K++ +G G+ ++ K+E E
Sbjct: 151 EKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKE 210
Query: 949 --------ITHELQDFAVDDPHDDKEEQDLDQQGNEE 977
E +D V + ++E+ D+ GNEE
Sbjct: 211 NEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEE 247
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 50.4 bits (119), Expect = 9e-06
Identities = 56/259 (21%), Positives = 109/259 (42%), Gaps = 26/259 (10%)
Query: 665 WRHQGERKVRVQDEDMETLASCTSELISEE---------MEQLDGGDTSSDEDKEEHETP 715
WR + E K D+ E +S E+ SEE +++L+ ++ S E++EE E
Sbjct: 2197 WRKRKEAKRG--DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEE 2254
Query: 716 VEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETL 775
E E +E++ R+E E +EE E + E EE K + + K+E +E
Sbjct: 2255 EERE------EEEV-----REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303
Query: 776 NYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSKSQSRRHLSAKER---REMKKKKLPSD 832
+ ++ + S+ +EES + + + + L +++ +E ++K L
Sbjct: 2304 EVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGR 2363
Query: 833 SGDLEALEGKDKEKESTVHIETHQNTSKN-VAAVQPMKRGQKSKMKKMKEKYKDQDEEDR 891
L L G K + + ++ K ++ MK + + + ++D+
Sbjct: 2364 ERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKKATVV 2423
Query: 892 ELIMKLLGSAGSNKEEKGK 910
E+ K LG+ +E GK
Sbjct: 2424 EIPRKFLGTMDKEREVMGK 2442
Score = 45.1 bits (105), Expect = 4e-04
Identities = 75/338 (22%), Positives = 137/338 (40%), Gaps = 52/338 (15%)
Query: 668 QGERKVRVQ---DEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQV 724
QG++++R + ++ + L L E+M ++G +T S K E MTQV
Sbjct: 1945 QGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLS---KGETPETSRQRKMTQV 2001
Query: 725 DQEDITLQSGRDE---LNEE--LIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPD 779
+QE + +E L+E+ L EES +G+ E R + V + + +
Sbjct: 2002 EQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIK 2061
Query: 780 TTIDLSHLQPQ-----RSIQKLASKEESSNSSDSK-SQSRRHLSAKERREMKKKKLPSDS 833
LS + +++QKL E + K ++ +R L KERR L +
Sbjct: 2062 KRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERR------LSIEQ 2115
Query: 834 GDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDREL 893
L+ E EK S + +K+ + +R +KM++M K + EE+ +L
Sbjct: 2116 SKLDIKEWDFSEKRSEL--------TKDEKKLARKQRKLANKMRRMINKEEKMTEEESKL 2167
Query: 894 IMKLLGSAGSNKEEKG--------------KKGKKGKTKDEPVKKQPQKPRGGQRVSDNI 939
K ++EE G +K K+ K D+P +K + D +
Sbjct: 2168 ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQ-------VDEV 2220
Query: 940 KKETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEE 977
+ E F E + L + + +EE++ +++ E
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258
Score = 43.5 bits (101), Expect = 0.001
Identities = 65/311 (20%), Positives = 131/311 (42%), Gaps = 48/311 (15%)
Query: 665 WRHQGERKVRVQDEDMETLASCTSELISEEMEQLDGGDTSSDEDKEEHETPVEVELMTQV 724
W+ + E+++ ++E + E +S E E L EDK+ ++ E QV
Sbjct: 1481 WKEEWEKRLLQEEEKLHQ----AGEKLSPEEEMLQ-------EDKK-----LKWEEWKQV 1524
Query: 725 DQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDL 784
+ ++ +S + +E +E + E+E E K+Q E + EE + I
Sbjct: 1525 WENMLSSKSKEQQYKDE--EEVTLEEEVSREGEEKEQQVTEEQRHIQEE---HKWARI-- 1577
Query: 785 SHLQPQRSIQKLASKEESSNSSDSK-SQSRRHLSAKERREMKKK-KLPSDSGDLEALEGK 842
H + R+ +K A +E + K +Q R L+ +ER+ + K+ D ++ EGK
Sbjct: 1578 -HRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGK 1636
Query: 843 DKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAG 902
+KE T+ + + + Q K KK+ +K++ E+ +L
Sbjct: 1637 FAQKEETLAQRGEKLSQEAEKLAQ--------KRKKLAKKWEKVAREEEKLAK------- 1681
Query: 903 SNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHELQDFAVDDPH 962
K GK + K+ +K + P+ Q + K+ LE + ++++ + +
Sbjct: 1682 -------KGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEE 1734
Query: 963 DDKEEQDLDQQ 973
++EE L ++
Sbjct: 1735 LNQEEGKLVEE 1745
Score = 38.9 bits (89), Expect = 0.026
Identities = 43/205 (20%), Positives = 99/205 (48%), Gaps = 34/205 (16%)
Query: 793 IQKLASKEESSNSSDSKSQSRRH----LSAKE-------------RREMKKKKLPSDSGD 835
++++ +KEE +SK +R+H L +E +R +K+K
Sbjct: 2150 MRRMINKEEKMTEEESKL-ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRK------- 2201
Query: 836 LEALEG-KDKEKESTV--HIETHQNTSKNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRE 892
EA G K KEK S+ +E+ ++ S+ + ++ Q+S + +E+ ++++E + E
Sbjct: 2202 -EAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE 2260
Query: 893 LIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIKKETPFLEVITHE 952
+ + +EE+G++ + K ++E KK+ +K + + + + +E E I E
Sbjct: 2261 EVRE--EEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK---EEIMSE 2315
Query: 953 LQDFAVDDPHDDKEEQDLDQQGNEE 977
+ ++ D +++E L+++ + E
Sbjct: 2316 EETESLSDEEEEEESCSLEEEVDRE 2340
Score = 31.6 bits (70), Expect = 4.2
Identities = 118/669 (17%), Positives = 260/669 (38%), Gaps = 66/669 (9%)
Query: 315 QEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDR--AIQVVRSALANQ 372
QEK+ ++L+ + D E E + +E+++ +G+L+E ++ + A+ R L+ +
Sbjct: 1710 QEKELAQELEELEWDME---ELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEE 1766
Query: 373 IDWT--EIGLIVKEAQAQGDPVASAIKELKLQTNHVTMLLRNPYLLSEEEDDDVDGDVNV 430
E L+++E + +E + L+ L+++ + ++ +
Sbjct: 1767 ETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEEL 1826
Query: 431 EKNETEPPKGKKKKQKNKQLQKPQK-----------NKPLLVDVDLSLSAYANAKKYYDH 479
KN+ + K Q+ K L + ++ NK L L N ++
Sbjct: 1827 TKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFN- 1885
Query: 480 KRYAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENY 539
+ A+ +K + E K EK + K VQ S+ K ++ EK +
Sbjct: 1886 -KILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKA-- 1942
Query: 540 LIIGGRDQQQNEIIVKRYLTPGDIYVHA------DLHGATSCVIKNPTGEPIPPRTLTEA 593
++ G+ + + E+ + + ++ + L + K T E R +T+
Sbjct: 1943 -MVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQV 2001
Query: 594 GTMALCYSAAWDARVITSAWWVYHHQVSKTAPTGEYLTTGS-FMIRGKKNFLPPSYLMMG 652
+ + +++ + + S+ A T G ++G++ S ++
Sbjct: 2002 EQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIK 2061
Query: 653 F--------SFLFKVDESCVWRHQGERKVRVQDEDMETLASCT---SELISEEMEQLDGG 701
+ L K+ ++ + ERK+ ++ M + +S E +LD
Sbjct: 2062 KRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIK 2121
Query: 702 DTSSDEDKEEHETPVEVELMTQVDQEDITLQSGRDELNEELIQEESSEDEGEYEEVRKDQ 761
+ E + E T E +L + Q + + R EE + EE S+ ++ EV D
Sbjct: 2122 EWDFSEKRSEL-TKDEKKLARK--QRKLANKMRRMINKEEKMTEEESKLARKHSEVILDD 2178
Query: 762 DSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASK-EESSNSSDSKSQSRRHLSAKE 820
+ G +++E E + + L +R K K +E +S + +S H S +
Sbjct: 2179 EEEGGIEEE--EVIPF------LKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEM 2230
Query: 821 RR---EMKKKKLPSDSGDLEALEGKDKEKESTVHIETHQNTSKNVAAVQPMKRGQKSKMK 877
E++K++ S + E E +++E+E E + + G++ +++
Sbjct: 2231 ESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEE---------GEEKQVE 2281
Query: 878 KMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKDEPVKKQP-QKPRGGQRVS 936
K +E+ K + +E ++ ++ KEE + + DE +++ R
Sbjct: 2282 KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341
Query: 937 DNIKKETPF 945
+ +KKE F
Sbjct: 2342 EILKKEKQF 2350
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,823,711
Number of Sequences: 37866
Number of extensions: 1915436
Number of successful extensions: 15338
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 194
Number of HSP's successfully gapped in prelim test: 893
Number of HSP's that attempted gapping in prelim test: 9471
Number of HSP's gapped (non-prelim): 4697
length of query: 1076
length of database: 18,247,518
effective HSP length: 113
effective length of query: 963
effective length of database: 13,968,660
effective search space: 13451819580
effective search space used: 13451819580
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.