Search of human proteins with 31982895

Search of human proteins with 31982895

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31982895 THAP domain containing 4 [Homo sapiens]
         (577 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31982895 THAP domain containing 4 [Homo sapiens]                  1162   0.0  
gi|194440668 THAP domain containing 5 isoform 1 [Homo sapiens]         96   7e-20
gi|8922446 THAP domain containing, apoptosis associated protein ...    82   2e-15
gi|22749337 THAP domain containing 8 [Homo sapiens]                    77   4e-14
gi|13899259 THAP domain containing, apoptosis associated protein...    68   2e-11
gi|42734379 THAP domain containing, apoptosis associated protein...    62   1e-09
gi|56788351 THAP domain containing 7 isoform 2 [Homo sapiens]          60   7e-09
gi|56788349 THAP domain containing 7 isoform 1 [Homo sapiens]          60   7e-09
gi|194440673 THAP domain containing 5 isoform 2 [Homo sapiens]         57   5e-08
gi|21389507 THAP domain containing 6 [Homo sapiens]                    54   4e-07
gi|94536788 THAP domain containing 9 [Homo sapiens]                    53   9e-07
gi|167736355 mucin 4 isoform a [Homo sapiens]                          48   3e-05
gi|19923268 protein-kinase, interferon-inducible double stranded...    46   8e-05
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 46   1e-04
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 46   1e-04
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  46   1e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    45   1e-04
gi|153070260 myristoylated alanine-rich protein kinase C substra...    45   2e-04
gi|4506975 solute carrier family 12 (sodium/potassium/chloride t...    44   4e-04
gi|222446620 hypothetical protein LOC342346 [Homo sapiens]             43   7e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        43   7e-04
gi|239752511 PREDICTED: hypothetical protein, partial [Homo sapi...    42   0.001
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    42   0.001
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]     42   0.001
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]     42   0.001
gi|55741677 SET domain containing 1A [Homo sapiens]                    42   0.002
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             42   0.002
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             42   0.002
gi|145199237 transcription elongation factor B polypeptide 3 bin...    42   0.002
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    40   0.004

>gi|31982895 THAP domain containing 4 [Homo sapiens]
          Length = 577

 Score = 1162 bits (3005), Expect = 0.0
 Identities = 577/577 (100%), Positives = 577/577 (100%)

Query: 1   MVICCAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHF 60
           MVICCAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHF
Sbjct: 1   MVICCAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHF 60

Query: 61  TKDSFSKRLEDQHRLLKPTAVPSIFHLTEKKRGAGGHGRTRRKDASKATGGVRGHSSAAT 120
           TKDSFSKRLEDQHRLLKPTAVPSIFHLTEKKRGAGGHGRTRRKDASKATGGVRGHSSAAT
Sbjct: 61  TKDSFSKRLEDQHRLLKPTAVPSIFHLTEKKRGAGGHGRTRRKDASKATGGVRGHSSAAT 120

Query: 121 GRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLA 180
           GRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLA
Sbjct: 121 GRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLA 180

Query: 181 TMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSF 240
           TMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSF
Sbjct: 181 TMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSF 240

Query: 241 SSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSP 300
           SSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSP
Sbjct: 241 SSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSP 300

Query: 301 SAPPADVTPKPATEAVQSEHSDASPMSINEVILSASGACKLIDSLHSYCFSSRQNKSQVC 360
           SAPPADVTPKPATEAVQSEHSDASPMSINEVILSASGACKLIDSLHSYCFSSRQNKSQVC
Sbjct: 301 SAPPADVTPKPATEAVQSEHSDASPMSINEVILSASGACKLIDSLHSYCFSSRQNKSQVC 360

Query: 361 CLREQVEKKNGELKSLRQRVSRSDSQVRKLQEKLDELRRVSVPYPSSLLSPSREPPKMNP 420
           CLREQVEKKNGELKSLRQRVSRSDSQVRKLQEKLDELRRVSVPYPSSLLSPSREPPKMNP
Sbjct: 361 CLREQVEKKNGELKSLRQRVSRSDSQVRKLQEKLDELRRVSVPYPSSLLSPSREPPKMNP 420

Query: 421 VVEPLSWMLGTWLSDPPGAGTYPTLQPFQYLEEVHISHVGQPMLNFSFNSFHPDTRKPMH 480
           VVEPLSWMLGTWLSDPPGAGTYPTLQPFQYLEEVHISHVGQPMLNFSFNSFHPDTRKPMH
Sbjct: 421 VVEPLSWMLGTWLSDPPGAGTYPTLQPFQYLEEVHISHVGQPMLNFSFNSFHPDTRKPMH 480

Query: 481 RECGFIRLKPDTNKVAFVSAQNTGVVEVEEGEVNGQELCIASHSIARISFAKEPHVEQIT 540
           RECGFIRLKPDTNKVAFVSAQNTGVVEVEEGEVNGQELCIASHSIARISFAKEPHVEQIT
Sbjct: 481 RECGFIRLKPDTNKVAFVSAQNTGVVEVEEGEVNGQELCIASHSIARISFAKEPHVEQIT 540

Query: 541 RKFRLNSEGKLEQTVSMATTTQPMTQHLHVTYKKVTP 577
           RKFRLNSEGKLEQTVSMATTTQPMTQHLHVTYKKVTP
Sbjct: 541 RKFRLNSEGKLEQTVSMATTTQPMTQHLHVTYKKVTP 577


>gi|194440668 THAP domain containing 5 isoform 1 [Homo sapiens]
          Length = 395

 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 48/90 (53%), Positives = 62/90 (68%), Gaps = 3/90 (3%)

Query: 5  CAAVNCSNRQGKGEK-RAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHFTKD 63
          CAA+ C NR+G+  K R +SF+ FPL D +RL +WLK ++RD+W P+KY FLCS+HFT D
Sbjct: 5  CAAICCKNRRGRNNKDRKLSFYPFPLHDKERLEKWLKNMKRDSWVPSKYQFLCSDHFTPD 64

Query: 64 SFSKRLEDQHRLLKPTAVPSIFHLTEKKRG 93
          S   R     R LK TAVP+IF L E  +G
Sbjct: 65 SLDIRW--GIRYLKQTAVPTIFSLPEDNQG 92


>gi|8922446 THAP domain containing, apoptosis associated protein 1
          isoform 1 [Homo sapiens]
          Length = 213

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 44/89 (49%), Positives = 55/89 (61%), Gaps = 4/89 (4%)

Query: 1  MVICCAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHF 60
          MV  C+A  C NR  K   + VSFH+FPL       +W  AV+R N+ PTKYS +CSEHF
Sbjct: 1  MVQSCSAYGCKNRYDKD--KPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKYSSICSEHF 58

Query: 61 TKDSFSKRLEDQHRLLKPTAVPSIFHLTE 89
          T D F +  E  ++LLK  AVP+IF  TE
Sbjct: 59 TPDCFKR--ECNNKLLKENAVPTIFLCTE 85



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 38/186 (20%), Positives = 73/186 (39%), Gaps = 30/186 (16%)

Query: 232 IGSLHSYSFSSKHTRERP-SVPREPIDRKRLKKDVEPSCSGSSLGPDKGLA--------- 281
           + S  +Y   +++ +++P S  + P+ R  L K+ E +    +  P K  +         
Sbjct: 2   VQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKYSSICSEHFTPD 61

Query: 282 -------------QSPPSSSLTATPQKPSQSPSAPPADVTPKPATEAV-QSEHSDASPMS 327
                         + P+  L   P    +    P   + P P    V Q + +    M 
Sbjct: 62  CFKRECNNKLLKENAVPTIFLCTEPHDKKEDLLEPQEQLPPPPLPPPVSQVDAAIGLLMP 121

Query: 328 INEVILSASGACKLIDSLHSYCFSSRQN-KSQVCCLREQVEKKNGELKSLRQRVSRSDSQ 386
             +  ++ S  C      H+Y      + + ++  L +QVEK   +LK+ +QR  R + Q
Sbjct: 122 PLQTPVNLSVFCD-----HNYTVEDTMHQRKRIHQLEQQVEKLRKKLKTAQQRCRRQERQ 176

Query: 387 VRKLQE 392
           + KL+E
Sbjct: 177 LEKLKE 182


>gi|22749337 THAP domain containing 8 [Homo sapiens]
          Length = 274

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 44/105 (41%), Positives = 57/105 (54%), Gaps = 9/105 (8%)

Query: 5   CAAVNCSNRQGK--GEKRAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHFTK 62
           C A NCSN  G+   + R VSF++FPLKD  RL  WL+ +  ++W P+ +  LCSEHFT 
Sbjct: 5   CRAPNCSNTAGRLGADNRPVSFYKFPLKDGPRLQAWLQHMGCEHWVPSCHQHLCSEHFTP 64

Query: 63  DSFSKRLEDQHRLLKPTAVPSIFHLTEKKRGAGGHGRTRRKDASK 107
             F  R     R L+P AVPSIF      RG     + R +   K
Sbjct: 65  SCFQWRW--GVRYLRPDAVPSIF-----SRGPPAKSQRRTRSTQK 102


>gi|13899259 THAP domain containing, apoptosis associated protein
          2 [Homo sapiens]
          Length = 228

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 38/81 (46%), Positives = 49/81 (60%), Gaps = 5/81 (6%)

Query: 5  CAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHFTKDS 64
          CAA  C+    K     +SFHRFPL D KR  +W++ V+R N+ P K++FLCS+HF    
Sbjct: 5  CAAAGCATTYNKHIN--ISFHRFPL-DPKRRKEWVRLVRRKNFVPGKHTFLCSKHFEASC 61

Query: 65 FSKRLEDQHRLLKPTAVPSIF 85
          F   L  Q R LK  AVP+IF
Sbjct: 62 FD--LTGQTRRLKMDAVPTIF 80


>gi|42734379 THAP domain containing, apoptosis associated protein 3
           [Homo sapiens]
          Length = 175

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 47/161 (29%), Positives = 72/161 (44%), Gaps = 25/161 (15%)

Query: 5   CAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHFTKDS 64
           CAA  C NR     K+ ++FHRFP    + L +W+  + R N+ P +++ +CSEHF  + 
Sbjct: 5   CAARQCCNRYSSRRKQ-LTFHRFPFSRPELLKEWVLNIGRGNFKPKQHTVICSEHFRPEC 63

Query: 65  FSKRLEDQHRLLKPTAVPSIFHLTEKKRGAGGHGRTRRKDASKATGGVRGHSSAATGRGA 124
           FS       + LK  AVP++F   +                   T  VR ++  A+ RG 
Sbjct: 64  FS--AFGNRKNLKHNAVPTVFAFQD------------------PTQQVRENTDPASERGN 103

Query: 125 AGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQE 165
           A    SSS      P   ++   A  GE +P    + A +E
Sbjct: 104 A----SSSQKEKTSPCRSQVLPEAGAGEDSPGRNMDTALEE 140


>gi|56788351 THAP domain containing 7 isoform 2 [Homo sapiens]
          Length = 309

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 65/248 (26%), Positives = 98/248 (39%), Gaps = 26/248 (10%)

Query: 5   CAAVNCSNRQGKGEK-RAVSFHRFPLKDSKRLIQWLKAVQRDN------WTP-TKYSFLC 56
           C+A  C  R  +  + R +SFHR P KD+ R   WL   QR +      W P ++Y + C
Sbjct: 5   CSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEYIYFC 64

Query: 57  SEHFTKDSFSKRLEDQHRLLKPTAVPSIFHLTEK-KRGAGGHGRTRRKDASKATGGVRGH 115
           S+HF +D F       +  LK  AVP+IF    K +R     G +     ++ +   R  
Sbjct: 65  SKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRLRRCR 124

Query: 116 SSAATGRG-AAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERT 174
              + GRG    +SP    +    P            EA+  A   A+   + +  L   
Sbjct: 125 KRCSEGRGPTTPFSPPPPADVTCFPVE----------EASAPATLPASPAGRLEPGLSSP 174

Query: 175 PGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGS 234
             D L  +  G+Q      +     E   S +E      S   +    PP +GA  +I +
Sbjct: 175 FSDLLGPL--GAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLR--LPPPAGA--YIQN 228

Query: 235 LHSYSFSS 242
            HSY   S
Sbjct: 229 EHSYQVGS 236


>gi|56788349 THAP domain containing 7 isoform 1 [Homo sapiens]
          Length = 309

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 65/248 (26%), Positives = 98/248 (39%), Gaps = 26/248 (10%)

Query: 5   CAAVNCSNRQGKGEK-RAVSFHRFPLKDSKRLIQWLKAVQRDN------WTP-TKYSFLC 56
           C+A  C  R  +  + R +SFHR P KD+ R   WL   QR +      W P ++Y + C
Sbjct: 5   CSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEYIYFC 64

Query: 57  SEHFTKDSFSKRLEDQHRLLKPTAVPSIFHLTEK-KRGAGGHGRTRRKDASKATGGVRGH 115
           S+HF +D F       +  LK  AVP+IF    K +R     G +     ++ +   R  
Sbjct: 65  SKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRLRRCR 124

Query: 116 SSAATGRG-AAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERT 174
              + GRG    +SP    +    P            EA+  A   A+   + +  L   
Sbjct: 125 KRCSEGRGPTTPFSPPPPADVTCFPVE----------EASAPATLPASPAGRLEPGLSSP 174

Query: 175 PGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGS 234
             D L  +  G+Q      +     E   S +E      S   +    PP +GA  +I +
Sbjct: 175 FSDLLGPL--GAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLR--LPPPAGA--YIQN 228

Query: 235 LHSYSFSS 242
            HSY   S
Sbjct: 229 EHSYQVGS 236


>gi|194440673 THAP domain containing 5 isoform 2 [Homo sapiens]
          Length = 353

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 28/52 (53%), Positives = 35/52 (67%), Gaps = 2/52 (3%)

Query: 42 VQRDNWTPTKYSFLCSEHFTKDSFSKRLEDQHRLLKPTAVPSIFHLTEKKRG 93
          ++RD+W P+KY FLCS+HFT DS   R     R LK TAVP+IF L E  +G
Sbjct: 1  MKRDSWVPSKYQFLCSDHFTPDSLDIRW--GIRYLKQTAVPTIFSLPEDNQG 50


>gi|21389507 THAP domain containing 6 [Homo sapiens]
          Length = 222

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 35/102 (34%), Positives = 54/102 (52%), Gaps = 14/102 (13%)

Query: 1  MVICCAAVNCSNRQGKGEK-RAVSFHRFPLKDSKRLIQWLKAVQRDN------WTPTKYS 53
          MV CC+A+ C++R     K + ++FH FP  ++ +  +W+ A++R +      W P K  
Sbjct: 1  MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKR-KWVLAMKRLDVNAAGIWEPKKGD 59

Query: 54 FLCSEHFTKDSFSKRLEDQHRLLKPTAVPSIF----HLTEKK 91
           LCS HF K  F +   +    LKP  +PSIF    HL  K+
Sbjct: 60 VLCSRHFKKTDFDRSAPNIK--LKPGVIPSIFDSPYHLQGKR 99


>gi|94536788 THAP domain containing 9 [Homo sapiens]
          Length = 903

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 11/110 (10%)

Query: 1   MVICCAAVNCSNRQGK-GEKRAVSFHRFPLKDSKRLIQWLKAVQRDN------WTPTKYS 53
           M   C+AV CS R      +R +SFH+FP  D+ +  +W++AV R +      W P   +
Sbjct: 1   MTRSCSAVGCSTRDTVLSRERGLSFHQFPT-DTIQRSKWIRAVNRVDPRSKKIWIPGPGA 59

Query: 54  FLCSEHFTKDSFSKRLEDQHRLLKPTAVPSIFHLTEKKRGAGGHGRTRRK 103
            LCS+HF +  F        R LK  AVPS+  L +  +G    G+ R+K
Sbjct: 60  ILCSKHFQESDFES--YGIRRKLKKGAVPSV-SLYKIPQGVHLKGKARQK 106


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 60/246 (24%), Positives = 91/246 (36%), Gaps = 26/246 (10%)

Query: 104  DASKATGG------VRGHSSAATGRGA----AGWSPSSSGNPMAKPESRRLKQAALQGEA 153
            DAS A+ G      V   SSA+TG        G S +S+G+    P +     +A  G A
Sbjct: 2389 DASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTN--VSSASTGHA 2446

Query: 154  TPRAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDK 213
            TP      +S        + TP  G  T    +        TDA   S   +    VT  
Sbjct: 2447 TPLPVTSTSSASTG----DTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSP 2502

Query: 214  SGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSS 273
            S  S    TP        +    + S S+  T   P      +  +        S S +S
Sbjct: 2503 SSASTGHTTP--------LPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSAS 2554

Query: 274  LGPDKGLAQSPPSSSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEV 331
             G    L  +  S++ T  ATP   + + SA   D TP P T+   +    A+P+ + + 
Sbjct: 2555 TGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDT 2614

Query: 332  ILSASG 337
              +++G
Sbjct: 2615 SSASTG 2620



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 65/253 (25%), Positives = 90/253 (35%), Gaps = 24/253 (9%)

Query: 104  DASKATGG------VRGHSSAATGRGAA--GWSPSSSGNPMAKPESRRLKQAALQGEATP 155
            D S A+ G      V   SSA+TG          SS+    A P       +A  G A P
Sbjct: 2165 DTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIP 2224

Query: 156  RAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSG 215
                + +S    Q     TP    +   A +        TDA   S   +    VT  S 
Sbjct: 2225 LLVTDTSSASTGQA----TPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSS 2280

Query: 216  ISMDDFTP-----PGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEP--- 267
            +S  D TP     P S +      LH    SS  T     +P   +       D  P   
Sbjct: 2281 VSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTG-DTTPLPV 2339

Query: 268  -SCSGSSLGPDKGLAQSPPSSSLTA--TPQKPSQSPSAPPADVTPKPATEAVQSEHSDAS 324
             S S +S G    L  +  SS  T   TP   + S SA     TP P T+A  +   D +
Sbjct: 2340 TSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTT 2399

Query: 325  PMSINEVILSASG 337
            P+ + +   +++G
Sbjct: 2400 PLPVTDTSSASTG 2412



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 53/233 (22%), Positives = 81/233 (34%), Gaps = 22/233 (9%)

Query: 112  VRGHSSAATGRGAA--GWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQ 169
            V   SS +TG        SPSS+    A P       +A  G+ TP     A+S      
Sbjct: 3875 VTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHA 3934

Query: 170  ALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTP-----P 224
                TP    +   A     +    TDA   S   +    +T  S +S  D TP      
Sbjct: 3935 ----TPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDT 3990

Query: 225  GSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSP 284
             S +      L   S SS  T +   +P              PS + S       +  + 
Sbjct: 3991 SSASTGQATPLPVTSLSSVSTGDTTPLPV-----------TIPSSASSGHTTSLPVTDAS 4039

Query: 285  PSSSLTATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVILSASG 337
              S+   TP   + + SA   D TP P T+   +    A+P+ + +   +++G
Sbjct: 4040 SVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTG 4092



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 49/210 (23%), Positives = 74/210 (35%), Gaps = 26/210 (12%)

Query: 128  SPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQ 187
            SPSS+    A P       +A  G+ATP    + +S   A       P  GL++  A + 
Sbjct: 1733 SPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHAT--PLPVTGLSS--ASTD 1788

Query: 188  GKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRE 247
                   TD    S   +I   VT  S  S  D TP           L     SS  T +
Sbjct: 1789 DTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTP-----------LPVTDASSASTGD 1837

Query: 248  RPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSPSAPPADV 307
              S+P              PS + S       +  +   S+  AT    + + S    D 
Sbjct: 1838 TTSLPV-----------TIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDT 1886

Query: 308  TPKPATEAVQSEHSDASPMSINEVILSASG 337
            TP P T+   +   D +P+ + +    ++G
Sbjct: 1887 TPLPVTDTNSASTGDTTPLHVTDASSVSTG 1916



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 58/245 (23%), Positives = 86/245 (35%), Gaps = 38/245 (15%)

Query: 116  SSAATGRGA----AGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQ--- 168
            SS +TG        G S +S+G+    P +     +A  G+ATP      +S        
Sbjct: 3223 SSVSTGHATPLPVTGLSSASTGDTTRLPVTDI--SSASTGQATPLPVTNTSSVSTGDTMP 3280

Query: 169  ----QALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGG-----VTDKSGISMD 219
                     + G      V  +   +   AT     S +S+  G      VTD S  S  
Sbjct: 3281 LPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTG 3340

Query: 220  DFTP-----PGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSL 274
            D TP     P S +      LH    SS  T +  ++P                 S +S 
Sbjct: 3341 DTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLP-------------VTGASSAST 3387

Query: 275  GPDKGLAQSPPSSSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVI 332
            G    L  +  SS  T  ATP   +   S    D TP P T+A  +    A+P+ +  + 
Sbjct: 3388 GHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLS 3447

Query: 333  LSASG 337
              ++G
Sbjct: 3448 SVSTG 3452



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 50/206 (24%), Positives = 71/206 (34%), Gaps = 32/206 (15%)

Query: 128  SPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQ 187
            SPSS+      P       +A  G ATP    +A+S          TP        A + 
Sbjct: 3605 SPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHA----TPLPVTDASSASTG 3660

Query: 188  GKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRE 247
                   TD    S   +    VT  S +S  D TP        +    + S S+ H   
Sbjct: 3661 DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP--------LPVTDASSASTGHATP 3712

Query: 248  RP-SVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLT--ATPQKPSQSPSAPP 304
             P ++P                 S  S G    L  + PSS+ T  ATP   +   SA  
Sbjct: 3713 LPVTIP-----------------SSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSAST 3755

Query: 305  ADVTPKPATEAVQSEHSDASPMSINE 330
             D TP P T+   +    A+P+ + +
Sbjct: 3756 GDTTPLPVTDTSSASTRHATPLPVTD 3781



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 67/270 (24%), Positives = 93/270 (34%), Gaps = 42/270 (15%)

Query: 104  DASKATGG------VRGHSSAATGRGAA--GWSPSSSGNPMAKPESRRLKQAALQGEATP 155
            DAS A+ G      V   SS +TG        SPSS+    A P       +A  G ATP
Sbjct: 1157 DASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATP 1216

Query: 156  RAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEA-SATDAGDESATSSIEGGVTDKS 214
                +A+S      + +      +    A S G       TD    S   +    VTD S
Sbjct: 1217 LPVTDASSV-----STDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTS 1271

Query: 215  GISMDDFTP-----PGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEP-- 267
             +S  D TP       S +   +  LH  S SS  T     +P   +       D  P  
Sbjct: 1272 SVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTG-DTMPLP 1330

Query: 268  --SCSGSSLGPDKGLAQSPPSSSLT------------------ATPQKPSQSPSAPPADV 307
              S S +S G    L  +  SS  T                  ATP   +   S    D 
Sbjct: 1331 VTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDT 1390

Query: 308  TPKPATEAVQSEHSDASPMSINEVILSASG 337
            TP P T    +    A+P+ + +   +++G
Sbjct: 1391 TPLPVTSPSSASTGHATPLLVTDTSSASTG 1420



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 56/236 (23%), Positives = 82/236 (34%), Gaps = 20/236 (8%)

Query: 116  SSAATGRGA----AGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQAL 171
            SSA+TG+         S  S+G+ M  P +     +A  G ATP      +S        
Sbjct: 3255 SSASTGQATPLPVTNTSSVSTGDTMPLPVTS--PSSASTGHATPLPVTSTSSASTGHA-- 3310

Query: 172  ERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTP-----PGS 226
              TP    +T  A +        TD    S   +    VT  S  S    TP     P S
Sbjct: 3311 --TPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSS 3368

Query: 227  GACKFIGSLH---SYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQS 283
             +     +L    + S S+ H    P      +           S S  S G    L  +
Sbjct: 3369 ASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVT 3428

Query: 284  PPSSSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVILSASG 337
              SS+ T  ATP   +   S    D TP   T+A       A+P+ + +   +++G
Sbjct: 3429 DASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTG 3484



 Score = 37.4 bits (85), Expect = 0.038
 Identities = 58/252 (23%), Positives = 86/252 (34%), Gaps = 28/252 (11%)

Query: 112  VRGHSSAATGRGA----AGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQA 167
            V   SSA+TG          S +S+G+ M  P +     +A  G+ TP    +A+S    
Sbjct: 1299 VTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTS--PSSASTGDTTPLPVTDASSVSTG 1356

Query: 168  QQA-LERTPGDGLATMVAGSQGKAEASATDAGDES-----ATSSIEGG------VTDKSG 215
                L  T     +T  A        S+   GD +     + SS   G      VTD S 
Sbjct: 1357 HTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSS 1416

Query: 216  ISMDDFTPPGSGACKFIGSLHSYSF--------SSKHTRERPSVPREPIDRKRLKKDVEP 267
             S    TP        + + H+ S         S+ HT   P          +    +  
Sbjct: 1417 ASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVT 1476

Query: 268  SCSGSSLGPDKGLAQSPPSSSLTA--TPQKPSQSPSAPPADVTPKPATEAVQSEHSDASP 325
              S  S G    L  +  SS+ T   TP   +   SA     TP P T    +   D  P
Sbjct: 1477 DTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMP 1536

Query: 326  MSINEVILSASG 337
            + +     +++G
Sbjct: 1537 LPVTSPSSASTG 1548



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 66/271 (24%), Positives = 94/271 (34%), Gaps = 39/271 (14%)

Query: 86   HLTEKKRGAGGHGRTRR-KDASKATGG------VRGHSSAATGRGAAGWSPSSSGNPMAK 138
            H+T     + GH       D S A+ G      V   SS +TG         ++  P+  
Sbjct: 2930 HVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTG--------DTTPLPVTS 2981

Query: 139  PESRRLKQAALQGEATPRAAQEAASQEQAQQ-ALERTPGDGLATMVAGSQGKAEASATDA 197
            P S      A  G  TP    + +S    Q  AL  T     +T  A +        TD 
Sbjct: 2982 PSS------ASTGHTTPLPVTDTSSASTGQATALPVT-----STSSASTGDTTPLPVTDT 3030

Query: 198  GDESATSSIEGGVTDKSGISMDDFTP-----PGSGACKFIGSLHSYSFSSKHTRERPSVP 252
               S   +    VT  S +S  D TP     P S +      L     SS  T +   +P
Sbjct: 3031 SSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLP 3090

Query: 253  REPIDRKRLKKDVEP----SCSGSSLGPDKGLAQSPPSSSLTA--TPQKPSQSPSAPPAD 306
               +       D  P    S S +S G    L  +  SS+ T   T    + + SA   D
Sbjct: 3091 VTSLSSVSTG-DTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGD 3149

Query: 307  VTPKPATEAVQSEHSDASPMSINEVILSASG 337
             T  P T+   S   D +P+ + E    ++G
Sbjct: 3150 TTSLPVTDTSSSSTGDTTPLLVTETSSVSTG 3180



 Score = 36.2 bits (82), Expect = 0.084
 Identities = 49/212 (23%), Positives = 72/212 (33%), Gaps = 16/212 (7%)

Query: 128  SPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQ 187
            S +SSG+  + P +     +   G AT     +A+S        + TP     T  A + 
Sbjct: 1847 SSASSGHTTSLPVTDA--SSVSTGHATSLLVTDASSVSTG----DTTPLPVTDTNSASTG 1900

Query: 188  GKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRE 247
                   TDA   S   +    VT  S  S  D TP        +      S SS HT  
Sbjct: 1901 DTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTP--------LPVTSPSSASSGHTTP 1952

Query: 248  RPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLT--ATPQKPSQSPSAPPA 305
             P      +             S  S G    L  +  SS  T  ATP   + + S    
Sbjct: 1953 LPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTG 2012

Query: 306  DVTPKPATEAVQSEHSDASPMSINEVILSASG 337
              TP P T    +   D +P+ + +   +++G
Sbjct: 2013 QATPLPVTSLSSASTGDTTPLPVTDTSSASTG 2044



 Score = 36.2 bits (82), Expect = 0.084
 Identities = 56/244 (22%), Positives = 81/244 (33%), Gaps = 22/244 (9%)

Query: 104  DASKATGG------VRGHSSAATGRGAA--GWSPSSSGNPMAKPESRRLKQAALQGEATP 155
            D S A+ G      V   SSA+ G   +      SS     A P       +A  G ATP
Sbjct: 2853 DTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATP 2912

Query: 156  RAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSG 215
                + +S           P    +   A +        TD    S   +    VT  S 
Sbjct: 2913 LPVTDTSSASTGHA----NPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSS 2968

Query: 216  ISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLG 275
            +S  D TP        +      S S+ HT   P          +       S S +S G
Sbjct: 2969 VSTGDTTP--------LPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTG 3020

Query: 276  PDKGLAQSPPSSSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVIL 333
                L  +  SS+ T  ATP   +   S    D TP P T    +    A+P+ + +   
Sbjct: 3021 DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASS 3080

Query: 334  SASG 337
            +++G
Sbjct: 3081 ASTG 3084



 Score = 36.2 bits (82), Expect = 0.084
 Identities = 61/249 (24%), Positives = 85/249 (34%), Gaps = 32/249 (12%)

Query: 104  DASKATGG------VRGHSSAATGRGAA--GWSPSSSGNPMAKPESRRLKQAALQGEATP 155
            DAS  + G      V   SSA+TG          SS+    A P       +   G+ TP
Sbjct: 3461 DASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP 3520

Query: 156  RAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSG 215
                +A+S          TP     T  A +        TD    S   +    VT  S 
Sbjct: 3521 LLVTDASSVSTGHA----TPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSS 3576

Query: 216  ISMDDFTP-----PGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCS 270
             S    TP       S +   +  LH  S SS  T     +P               S S
Sbjct: 3577 SSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLP-------------VTSTS 3623

Query: 271  GSSLGPDKGLAQSPPSSSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSI 328
             +S G    L  +  SS  T  ATP   + + SA   D TP P T+   +    A+P+ +
Sbjct: 3624 SASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPV 3683

Query: 329  NEVILSASG 337
              +   ++G
Sbjct: 3684 TSLSSVSTG 3692



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 60/252 (23%), Positives = 88/252 (34%), Gaps = 28/252 (11%)

Query: 112  VRGHSSAATGRGA----AGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQA 167
            V   SSA+TG          S +S+G+ M  P +     +A  G+ TP    +A+S    
Sbjct: 1507 VTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTS--PSSASTGDTTPLPVTDASSVSTG 1564

Query: 168  QQA-LERTPGDGLATMVAGSQGKAEASATDAGDES-----ATSSIEGG------VTDKSG 215
                L  T     +T         + S+   GD +     + SS   G      VTD S 
Sbjct: 1565 HTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSS 1624

Query: 216  ISMDDFTP-PGSGACKFIGS----LHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCS 270
             S  D TP P + A          LH  S SS  T     +P                 +
Sbjct: 1625 ASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVT 1684

Query: 271  GSSLGPDKGLAQSP-----PSSSLTATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASP 325
            G S        + P      +S+  ATP   +   S    D TP P T    +    ASP
Sbjct: 1685 GLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASP 1744

Query: 326  MSINEVILSASG 337
            + + +   +++G
Sbjct: 1745 LLVTDASSASTG 1756



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 61/274 (22%), Positives = 91/274 (33%), Gaps = 29/274 (10%)

Query: 86   HLTEKKRGAGGHGRTRRKDASKATGGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLK 145
            H+T     + GH  +     + A     GH   AT       S +S+G+    P +    
Sbjct: 2546 HVTSPSSASTGHATSLPVTDTSAAS--TGH---ATPLPVTSTSSASTGDTTPLPVTDTY- 2599

Query: 146  QAALQGEATPRAAQEAASQEQAQ-------QALERTPGDGLATMVAGSQGKAEASATDAG 198
             +A  G+ATP    + +S                 + G      V  +   +   AT   
Sbjct: 2600 -SASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLH 2658

Query: 199  DESATSSIEGG-----VTDKSGISMDDFT--PPGSGACKFIGSLHSY------SFSSKHT 245
              S +S+  G      VTD S +S    T  P    +  F G   S       S SS HT
Sbjct: 2659 VTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHT 2718

Query: 246  RERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLT--ATPQKPSQSPSAP 303
               P      +             S  S G    L  +  SS  T  ATP   +   S  
Sbjct: 2719 TPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVS 2778

Query: 304  PADVTPKPATEAVQSEHSDASPMSINEVILSASG 337
              D TP P T+   +    A+P+ +  +   ++G
Sbjct: 2779 TGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTG 2812



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 60/252 (23%), Positives = 84/252 (33%), Gaps = 38/252 (15%)

Query: 104  DASKATGG------VRGHSSAATGRGAA--GWSPSSSGNPMAKPESRRLKQAALQGEATP 155
            D S A+ G      V   SS +TG        SPSS+    A P       +A  G ATP
Sbjct: 1621 DTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATP 1680

Query: 156  RAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSG 215
                               P  GL++  A +        TD    S   +    VT  S 
Sbjct: 1681 ------------------LPVTGLSS--ATTDDTTRLPVTDVSSASTGQATPLPVTSLSS 1720

Query: 216  ISMDDFTP-----PGSGACKFIGSLHSYSFSSKHTRERPSVP---REPIDRKRLKKDVEP 267
            +S  D TP     P S +      L     SS  T +   +P      +           
Sbjct: 1721 VSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVT 1780

Query: 268  SCSGSSLGPDKGLAQSPPSSSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASP 325
              S +S      L  +  SS+ T  A P   +   SA   D TP P T+A  +   D + 
Sbjct: 1781 GLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTS 1840

Query: 326  MSINEVILSASG 337
            + +     ++SG
Sbjct: 1841 LPVTIPSSASSG 1852



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 48/212 (22%), Positives = 69/212 (32%), Gaps = 30/212 (14%)

Query: 128  SPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQ 187
            SPSS+    A P       +A  G+ TP    + +S          TP     T  A + 
Sbjct: 3733 SPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHA----TPLPVTDTSSASTD 3788

Query: 188  GKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRE 247
                   TD    S   +    VT  S  S  D TP        +    + S S+ H   
Sbjct: 3789 DTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTP--------LPVTDTSSVSTGHATS 3840

Query: 248  RPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLT--ATPQKPSQSPSAPPA 305
             P   R                S +S G    L  +  SS  T  ATP   + + S    
Sbjct: 3841 LPVTSR----------------SSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTG 3884

Query: 306  DVTPKPATEAVQSEHSDASPMSINEVILSASG 337
              TP P T    +    A+P+ +     +++G
Sbjct: 3885 HATPLPVTSPSSASTGHATPVPVTSTSSASTG 3916



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 57/252 (22%), Positives = 86/252 (34%), Gaps = 22/252 (8%)

Query: 128  SPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQA-LERTPGDGLATMVAGS 186
            SPSS+    A P       +A  G ATP      +S        L  T     +T  A  
Sbjct: 2293 SPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATP 2352

Query: 187  QGKAEASATDAGDES-----ATSSIEGG------VTDKSGISMDDFTP-----PGSGACK 230
                +AS+   GD +     ++SS   G      VTD S  S  D TP       S +  
Sbjct: 2353 LHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTG 2412

Query: 231  FIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVE---PSCSGSSLGPDKGLAQSPPSS 287
                L     SS  T +   +P   +              S S +S G    L  +  SS
Sbjct: 2413 HATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSS 2472

Query: 288  SLTA--TPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVILSASGACKLIDSL 345
              T   TP   + + S    D T  P T    +     +P+ + +   +++G    +   
Sbjct: 2473 VSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVT 2532

Query: 346  HSYCFSSRQNKS 357
            ++   S+R   S
Sbjct: 2533 NASSLSTRHATS 2544



 Score = 32.7 bits (73), Expect = 0.93
 Identities = 55/230 (23%), Positives = 81/230 (35%), Gaps = 18/230 (7%)

Query: 112  VRGHSSAATGRGAA--GWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQ 169
            V   SSA+TG          SS     A P       +A  G+ TP    + +S    Q 
Sbjct: 3619 VTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQA 3678

Query: 170  ALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTP-----P 224
                 P   L+++  G         TDA   S   +    VT  S +S  D  P     P
Sbjct: 3679 T--PLPVTSLSSVSTGDT--TPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSP 3734

Query: 225  GSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVE---PSCSGSSLGPDKGLA 281
             S +      L     SS  T +   +P         +          S +S      L 
Sbjct: 3735 SSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLP 3794

Query: 282  QSPPSSSLT--ATPQKPSQSPSAPPADVTPKPATE--AVQSEHSDASPMS 327
             +  SS+ T  ATP   + + SA   D TP P T+  +V + H+ + P++
Sbjct: 3795 VTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVT 3844



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 52/244 (21%), Positives = 83/244 (34%), Gaps = 22/244 (9%)

Query: 104  DASKATGG------VRGHSSAATGRGAA--GWSPSSSGNPMAKPESRRLKQAALQGEATP 155
            D S A+ G      V   SSA+TG        + SS     A P       +A  G  TP
Sbjct: 2613 DTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTP 2672

Query: 156  RAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSG 215
                +A+S           P    +++  G       +   +     T+ +   VTD S 
Sbjct: 2673 LPVTDASSVSTGHAT--SLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLP--VTDASS 2728

Query: 216  ISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLG 275
            +S        +G    +    + S S+ H    P      +           S S  S G
Sbjct: 2729 VS--------TGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTG 2780

Query: 276  PDKGLAQSPPSSSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVIL 333
                L  +  SS+ T  ATP   +   S    D TP P T+   +    A+ + + +   
Sbjct: 2781 DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSS 2840

Query: 334  SASG 337
            +++G
Sbjct: 2841 ASTG 2844



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 43/228 (18%), Positives = 84/228 (36%), Gaps = 13/228 (5%)

Query: 117  SAATGRGAAGWSPSSSGNPMAKPESRRL--KQAALQGEATPRAAQEAASQEQAQQALER- 173
            ++  GR     SP+S   P A P+      + A  Q   T R +   +   QA       
Sbjct: 879  ASTAGRPTGQSSPTS---PSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTV 935

Query: 174  --TPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKF 231
              TP    +T +   Q +    +     ++ T+++   +++ + + +   +   +G    
Sbjct: 936  PPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTAL---ISNATPLPVTYASSASTGHTTP 992

Query: 232  IGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLT- 290
            +    + S S+ H    P      +             S  S G    L  +  SS+ T 
Sbjct: 993  LHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTG 1052

Query: 291  -ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVILSASG 337
             +TP   + + SA    VTP P T    +   D +P+ + +   +++G
Sbjct: 1053 DSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTG 1100



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 51/234 (21%), Positives = 73/234 (31%), Gaps = 16/234 (6%)

Query: 116  SSAATGRGAA--GWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALER 173
            SSA+TG          SS     A P       +   G  TP    + +S+         
Sbjct: 983  SSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHV---- 1038

Query: 174  TPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTP--------PG 225
            TP    +   A +        TD    S        VT  S  S  D TP          
Sbjct: 1039 TPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSAS 1098

Query: 226  SGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPP 285
            +G    +    + S S+ HT   P                    S  S G    L  +  
Sbjct: 1099 TGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDA 1158

Query: 286  SSSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVILSASG 337
            SS+ T  ATP   +   S    D TP P T    +    A+P+ + +   +++G
Sbjct: 1159 SSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTG 1212



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 54/256 (21%), Positives = 87/256 (33%), Gaps = 36/256 (14%)

Query: 112  VRGHSSAATGRGAA----GWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQA 167
            V   SSA+TG   +      S +S+G+  + P +     +A  G+ T     + +S    
Sbjct: 3107 VTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDT--SSAYTGDTTSLPVTDTSSSSTG 3164

Query: 168  QQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSG 227
                + TP     T    +        TDA   S   +    VT  S  S  D TP    
Sbjct: 3165 ----DTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVT 3220

Query: 228  ACKFIGSLHSY-----SFSSKHTRERPSVPREPIDRKRLKKDVE---PSCSGSSLGPDKG 279
                + + H+        SS  T +   +P   I      +       + S  S G    
Sbjct: 3221 DTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMP 3280

Query: 280  LAQSPPSSSLT------------------ATPQKPSQSPSAPPADVTPKPATEAVQSEHS 321
            L  + PSS+ T                  ATP   + + SA     TP P T+   +   
Sbjct: 3281 LPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTG 3340

Query: 322  DASPMSINEVILSASG 337
            D +P+ +     +++G
Sbjct: 3341 DTTPLPVTSPSSASTG 3356



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 51/265 (19%), Positives = 103/265 (38%), Gaps = 29/265 (10%)

Query: 78   PTAVPSIFHLTEKKRGAGGHGRTRRKD-ASKATGGVRGHSSAATGRGAAGWSPSSSGNPM 136
            P    ++ H T +       G+T+  + AS  +      ++  +  GA+G +PS S    
Sbjct: 764  PDTAAAMTH-THQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGIS 822

Query: 137  AKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATD 196
               E+ R      +   T ++  E  S   +  A+  + G   +++V G+     + A+ 
Sbjct: 823  TSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMA-SSIVPGTFHPTLSEAST 881

Query: 197  AG---DESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPR 253
            AG    +S+ +S      + + IS    T       +      + S +S+ T    +VP 
Sbjct: 882  AGRPTGQSSPTSPSASPQETAAISRMAQTQ----RTRTSRGSDTISLASQATDTFSTVPP 937

Query: 254  EPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQS-PSAPPADVTPKPA 312
             P           PS + + L        SP + + T +P    ++  +A  ++ TP P 
Sbjct: 938  TP-----------PSITSTGL-------TSPQTETHTLSPSGSGKTFTTALISNATPLPV 979

Query: 313  TEAVQSEHSDASPMSINEVILSASG 337
            T A  +     +P+ + +    ++G
Sbjct: 980  TYASSASTGHTTPLHVTDASSVSTG 1004



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 57/246 (23%), Positives = 84/246 (34%), Gaps = 42/246 (17%)

Query: 104  DASKATGG------VRGHSSAATGRGA----AGWSPSSSGNPMAKPESRRLKQAALQGEA 153
            D S A+ G      V   SSA+TG          S +S+G+    P +     +   G A
Sbjct: 1589 DTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLST--GHA 1646

Query: 154  TPRAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDK 213
            TP      +S          TP    +T  A +        T     +   +    VTD 
Sbjct: 1647 TPLHVTSPSSASTGHA----TPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDV 1702

Query: 214  SGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSS 273
            S  S    TP           L   S SS  T +   +P               S S +S
Sbjct: 1703 SSASTGQATP-----------LPVTSLSSVSTGDTTPLP-------------VTSPSSAS 1738

Query: 274  LGPDKGLAQSPPSSSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEV 331
             G    L  +  SS+ T  ATP   + + S   A  TP P T    +   D + + + +V
Sbjct: 1739 TGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDV 1798

Query: 332  ILSASG 337
              +++G
Sbjct: 1799 SSASTG 1804



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 58/262 (22%), Positives = 88/262 (33%), Gaps = 27/262 (10%)

Query: 98   GRTRRKDASKATGGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRA 157
            G T     + A+    GH   AT       S +S+G+    P +     +A  G  TP  
Sbjct: 1900 GDTTPLHVTDASSVSTGH---ATSLPVTSLSSASTGDTTPLPVTS--PSSASSGHTTPLP 1954

Query: 158  AQEAASQEQAQQ-ALERTPGDGLATMVAGSQGKAEASATDAGDESA-----TSSIEGG-- 209
              +A+S       +L  T    ++T  A      +AS+   G  +      TSS+  G  
Sbjct: 1955 VTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQA 2014

Query: 210  ----VTDKSGISMDDFTP--------PGSGACKFIGSLHSYSFSSKHTRERPSVPREPID 257
                VT  S  S  D TP          +G    +      S S+  T   P        
Sbjct: 2015 TPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSAS 2074

Query: 258  RKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLT--ATPQKPSQSPSAPPADVTPKPATEA 315
                   +    S  S G    L  +  SS  T  AT    + + S    D TP P T  
Sbjct: 2075 TGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSP 2134

Query: 316  VQSEHSDASPMSINEVILSASG 337
              +   D +P+ + +    ++G
Sbjct: 2135 SSASTGDTTPLPVTDTSSVSTG 2156



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 55/247 (22%), Positives = 79/247 (31%), Gaps = 29/247 (11%)

Query: 98   GRTRRKDASKATGGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRA 157
            G T     + A+    GH   AT       S  S+G+    P +     +   G ATP  
Sbjct: 1948 GHTTPLPVTDASSVPTGH---ATSLPVTDASSVSTGHATPLPVTDA--SSVSTGHATPLP 2002

Query: 158  AQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGIS 217
              + +S    Q     TP    +   A +        TD    S        VT  S +S
Sbjct: 2003 VTDTSSVSTGQA----TPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVS 2058

Query: 218  MDDFTP-----PGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGS 272
              D TP     P S +      L     SS  T    S+             +    S  
Sbjct: 2059 TGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSL-------------LVTDASSV 2105

Query: 273  SLGPDKGLAQSPPSSSLTA--TPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINE 330
            S G    L  +  SS  T   TP   +   SA   D TP P T+        A+ + + +
Sbjct: 2106 STGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTD 2165

Query: 331  VILSASG 337
               +++G
Sbjct: 2166 TSSASTG 2172



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 53/233 (22%), Positives = 83/233 (35%), Gaps = 26/233 (11%)

Query: 128  SPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQAL-------ERTPGDGLA 180
            S +S+G+  + P +     +A  G ATP    + +S       L         + G   +
Sbjct: 2823 SSASTGHATSLPVTDT--SSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATS 2880

Query: 181  TMVAGSQGKAEASATDAGDESATSSIEGG-----VTDKSGISMDDFTP-----PGSGACK 230
              V  +   +   AT     S +S+  G      VTD S  S     P     P S +  
Sbjct: 2881 LPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTG 2940

Query: 231  FIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEP----SCSGSSLGPDKGLAQSPPS 286
                L     SS  T     +P   +       D  P    S S +S G    L  +  S
Sbjct: 2941 HATPLPVTDTSSASTGHATPLPVTSLSSVSTG-DTTPLPVTSPSSASTGHTTPLPVTDTS 2999

Query: 287  SSLT--ATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVILSASG 337
            S+ T  AT    + + SA   D TP P T+   +    A+P+ +  +   ++G
Sbjct: 3000 SASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTG 3052


>gi|19923268 protein-kinase, interferon-inducible double stranded
           RNA dependent inhibitor, repressor of (P58 repressor)
           [Homo sapiens]
          Length = 761

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 33/109 (30%), Positives = 56/109 (51%), Gaps = 11/109 (10%)

Query: 5   CAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQR---DNWTP---TKYSFLCSE 58
           CAA NC+ +  + +   ++F RFP +D  R  +W++  +R   ++ TP    K+  LC++
Sbjct: 5   CAAPNCTRKSTQSD---LAFFRFP-RDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAK 60

Query: 59  HFTKDSFSKRLEDQHRLLKPTAVPSIFHLTEKKRGAGGHGRTRRKDASK 107
           HF + S   R      +L+  A+P+IF LT          R R K+ S+
Sbjct: 61  HF-ETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSE 108


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 68/331 (20%), Positives = 120/331 (36%), Gaps = 33/331 (9%)

Query: 88   TEKKRGAGGHGRTRRKDASKATGGVRGHSSAATGRGAAGWSPSSSGN-PMAKP---ESRR 143
            T   RGA    ++     ++ T  + G S A +  G+   +PS     P+++P     R 
Sbjct: 2268 TTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRN 2327

Query: 144  LKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASAT-DAGDESA 202
                   G + P    +         A  ++ G G  +  +  +  ++ + T   G    
Sbjct: 2328 SISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKN 2387

Query: 203  TSSIEGGVTDKSGISMDDFTPPGSGACKFIG----SLHSYSFSSKHTRERPSVPREPIDR 258
             SSI    +   G++  +    G+GA K +     S    S S     ERP + R+    
Sbjct: 2388 ASSIPRSESASKGLNQMN---NGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFI 2444

Query: 259  KR-----LKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSPSAPPADVTPKPAT 313
            K      L++ +E S S  SL P      S P+S   +  Q P  SPS P   ++   + 
Sbjct: 2445 KEAPSPTLRRKLEESASFESLSPS-----SRPASPTRSQAQTPVLSPSLPDMSLSTHSSV 2499

Query: 314  EA-----------VQSEHSDASPMSINEVILSASGACKLIDSLHSYCFSSRQNKSQVCCL 362
            +A              E++D  P   +++  S S +   +    S  +    +K      
Sbjct: 2500 QAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLP 2559

Query: 363  REQVEKKNGELKSLRQRVSRSDSQVRKLQEK 393
            R    ++ G   S+    S S  + +   EK
Sbjct: 2560 RVSTWRRTGSSSSILSASSESSEKAKSEDEK 2590


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 68/331 (20%), Positives = 120/331 (36%), Gaps = 33/331 (9%)

Query: 88   TEKKRGAGGHGRTRRKDASKATGGVRGHSSAATGRGAAGWSPSSSGN-PMAKP---ESRR 143
            T   RGA    ++     ++ T  + G S A +  G+   +PS     P+++P     R 
Sbjct: 2268 TTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRN 2327

Query: 144  LKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASAT-DAGDESA 202
                   G + P    +         A  ++ G G  +  +  +  ++ + T   G    
Sbjct: 2328 SISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKN 2387

Query: 203  TSSIEGGVTDKSGISMDDFTPPGSGACKFIG----SLHSYSFSSKHTRERPSVPREPIDR 258
             SSI    +   G++  +    G+GA K +     S    S S     ERP + R+    
Sbjct: 2388 ASSIPRSESASKGLNQMN---NGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFI 2444

Query: 259  KR-----LKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSPSAPPADVTPKPAT 313
            K      L++ +E S S  SL P      S P+S   +  Q P  SPS P   ++   + 
Sbjct: 2445 KEAPSPTLRRKLEESASFESLSPS-----SRPASPTRSQAQTPVLSPSLPDMSLSTHSSV 2499

Query: 314  EA-----------VQSEHSDASPMSINEVILSASGACKLIDSLHSYCFSSRQNKSQVCCL 362
            +A              E++D  P   +++  S S +   +    S  +    +K      
Sbjct: 2500 QAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLP 2559

Query: 363  REQVEKKNGELKSLRQRVSRSDSQVRKLQEK 393
            R    ++ G   S+    S S  + +   EK
Sbjct: 2560 RVSTWRRTGSSSSILSASSESSEKAKSEDEK 2590


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 68/331 (20%), Positives = 120/331 (36%), Gaps = 33/331 (9%)

Query: 88   TEKKRGAGGHGRTRRKDASKATGGVRGHSSAATGRGAAGWSPSSSGN-PMAKP---ESRR 143
            T   RGA    ++     ++ T  + G S A +  G+   +PS     P+++P     R 
Sbjct: 2268 TTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRN 2327

Query: 144  LKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASAT-DAGDESA 202
                   G + P    +         A  ++ G G  +  +  +  ++ + T   G    
Sbjct: 2328 SISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKN 2387

Query: 203  TSSIEGGVTDKSGISMDDFTPPGSGACKFIG----SLHSYSFSSKHTRERPSVPREPIDR 258
             SSI    +   G++  +    G+GA K +     S    S S     ERP + R+    
Sbjct: 2388 ASSIPRSESASKGLNQMN---NGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFI 2444

Query: 259  KR-----LKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSPSAPPADVTPKPAT 313
            K      L++ +E S S  SL P      S P+S   +  Q P  SPS P   ++   + 
Sbjct: 2445 KEAPSPTLRRKLEESASFESLSPS-----SRPASPTRSQAQTPVLSPSLPDMSLSTHSSV 2499

Query: 314  EA-----------VQSEHSDASPMSINEVILSASGACKLIDSLHSYCFSSRQNKSQVCCL 362
            +A              E++D  P   +++  S S +   +    S  +    +K      
Sbjct: 2500 QAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLP 2559

Query: 363  REQVEKKNGELKSLRQRVSRSDSQVRKLQEK 393
            R    ++ G   S+    S S  + +   EK
Sbjct: 2560 RVSTWRRTGSSSSILSASSESSEKAKSEDEK 2590


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 57/250 (22%), Positives = 96/250 (38%), Gaps = 30/250 (12%)

Query: 187 QGKAEASATDAGDESATSS-IEGGVTDKSGISMDDF-TPPGSGACKFIGSLHSYSFSSKH 244
           + K +AS++D+ D S     ++G    K+ +       PPG  A K   S  S S  S  
Sbjct: 77  KAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAK--ASESSSSEESSD 134

Query: 245 TRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSPSAPP 304
             +     ++P+     +K V+P             A++PP  + ++     S S   PP
Sbjct: 135 DDDEEDQKKQPV-----QKGVKPQAKA---------AKAPPKKAKSSDSDSDSSSEDEPP 180

Query: 305 ADVTPK--PATEAVQSEHSDASPMSINEVILSASGACKLIDSLHSYCFSSRQNKSQVCCL 362
            +  PK  P T   Q++ +   P      I +   A     S  S      + +      
Sbjct: 181 KNQKPKITPVTVKAQTK-APPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239

Query: 363 REQVEKKNGELKS--------LRQRVSRSDSQVRKLQEKLDELRRVSVPYPSSLLSPSRE 414
           ++ V KK    K+         R+  S  DS   + +E+   ++    PY SS+  PS  
Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPY-SSVPPPSAP 298

Query: 415 PPKMNPVVEP 424
           PPK +   +P
Sbjct: 299 PPKKSLGTQP 308



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 23/114 (20%)

Query: 102 RKDASKATGGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEA 161
           +K   K  GG      A+  +G A  S SSS +  ++ E  +LK     G+ +PR     
Sbjct: 491 KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLK-----GKGSPR----- 540

Query: 162 ASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSG 215
               QA +A      +G + + A   GKA  ++ +  +E   +++   V  KSG
Sbjct: 541 ---PQAPKA------NGTSALTA-QNGKAAKNSEEEEEEKKKAAV---VVSKSG 581


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 54/271 (19%), Positives = 85/271 (31%), Gaps = 41/271 (15%)

Query: 89  EKKRGAGGHGRTRRKDASKATGGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAA 148
           E+ +  G      +++ + A  G    S+A  G  AA  +P +  +P+ K       +A 
Sbjct: 56  EELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEK-------EAP 108

Query: 149 LQGEATPRAAQEAASQEQAQQALER---------TPGDGLAT------------------ 181
            +GEA    +  AA  E A  A            TP     T                  
Sbjct: 109 AEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSG 168

Query: 182 -------MVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGS 234
                    AG  G+AEA A + G + A         +    S +    PG  A      
Sbjct: 169 FSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEG 228

Query: 235 LHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQ 294
                      +E    P +P      K   EPS        + G + +   +   A P 
Sbjct: 229 AAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPG 288

Query: 295 KPSQSPSAPPADVTPKPATEAVQSEHSDASP 325
            P +  +AP  +     A+ A  +   +A P
Sbjct: 289 APPEQEAAPAEEPAAAAASSACAAPSQEAQP 319



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 34/165 (20%), Positives = 60/165 (36%), Gaps = 25/165 (15%)

Query: 85  FHLTEKKRGAGGHGRTRRKDASK------------ATGGVRGHSSAATGRGAAGWSPSSS 132
           F   +K+ G GG       +  K              G   G  +AA G  AA     ++
Sbjct: 171 FKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAA 230

Query: 133 GNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVA-------- 184
           G     P+  + ++AA+  E  P A+ E  + E+  +  E+   +  A+  A        
Sbjct: 231 G---GDPQEAKPQEAAVAPEKPP-ASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAG 286

Query: 185 -GSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGA 228
            G+  + EA+  +    +A SS     + ++        PP   A
Sbjct: 287 PGAPPEQEAAPAEEPAAAAASSACAAPSQEAQPECSPEAPPAEAA 331


>gi|4506975 solute carrier family 12 (sodium/potassium/chloride
           transporters), member 2 [Homo sapiens]
          Length = 1212

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 46/150 (30%), Positives = 61/150 (40%), Gaps = 28/150 (18%)

Query: 105 ASKATGGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQ 164
           AS+  GGVR    AA G G         G P+    S+   Q  L  E   RAA  AA+ 
Sbjct: 49  ASRDGGGVRDEGPAAAGDGL--------GRPLGPTPSQSRFQVDLVSENAGRAAAAAAAA 100

Query: 165 EQAQQAL------ERTPGDGLATMVAGSQGKAEASATDAG-------DESATSSIEGGVT 211
             A  A       ++TP DG A   +G    A+ S    G       D +A+SS E  ++
Sbjct: 101 AAAAAAAGAGAGAKQTPADGEA---SGESEPAKGSEEAKGRFRVNFVDPAASSSAEDSLS 157

Query: 212 DKSGISMD----DFTPPGSGACKFIGSLHS 237
           D +G+ +D     F   G        SLHS
Sbjct: 158 DAAGVGVDGPNVSFQNGGDTVLSEGSSLHS 187


>gi|222446620 hypothetical protein LOC342346 [Homo sapiens]
          Length = 1141

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 69/335 (20%), Positives = 124/335 (37%), Gaps = 30/335 (8%)

Query: 81  VPSIFHLTEKKRGAGG-HGRTRRKDASKATGGV------RGHSS-AATGRGAAGWSPSSS 132
           VPS+  L E+ R  G    RTR+    K  GG       R H       RG     P   
Sbjct: 463 VPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDR 522

Query: 133 GNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDG-LATMVAGSQGKAE 191
            +    P+ R  K    +       A + A  +  Q AL R      +A   A +   A 
Sbjct: 523 AHKDDVPKDRGGKDGDPKDRVGKDGAPKEAQPKAPQSALHRLKTTAAIAAAAAAAYAAAT 582

Query: 192 ASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGA-CKFIGSLHSYSFSSKHTRERPS 250
           +SA  A   +A    +   T  + I+ D       G     +G+  S   +         
Sbjct: 583 SSAAQAAKVAAKFVKDAPATKMAAIATDTAAAGPLGVFADVLGAGPSRGATESQILG--- 639

Query: 251 VPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSPSAPPADVTPK 310
                 D   + + + PS S +S+GPD  L+Q+  ++    +P+   ++     + +   
Sbjct: 640 ------DDSEIYEILSPSYSAASIGPDPALSQAMVATKQAMSPEDKKRAVKYSMSHIAQI 693

Query: 311 PATEAVQSEHSDASPMSINE---VILSASGACKL---IDSLHSYCFSSRQNKSQVCCLRE 364
           P       E       ++N+    + +  G   L   +D L     S ++++ +     E
Sbjct: 694 PVKHDSLKEEFAQLSCNLNQRLSYLANMGGPSSLGTTVDILQKKIGSLQKSRLK----EE 749

Query: 365 QVEKKNG-ELKSLRQRVSRSDSQVRKLQEKLDELR 398
           ++E+  G +++ ++ R    D  V  LQ ++DE +
Sbjct: 750 ELERIWGNQIEMMKDRYITLDKAVENLQIRMDEFK 784


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 69/314 (21%), Positives = 113/314 (35%), Gaps = 33/314 (10%)

Query: 109  TGGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQ 168
            T  V G  S ++G  A   S +   N M    +  +  + +        AQ+ ++    Q
Sbjct: 2466 TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQ 2525

Query: 169  QALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGG-VTDKSGISMDDFTPPGSG 227
             A ER      ++  + S   + +S++ +   S++S  EG  +  +  +++     P   
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585

Query: 228  ACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSS 287
              + +               R   P EP   KR ++    S S SS       + S  SS
Sbjct: 2586 PKEAV---------------REGRPPEPTPAKRKRRS---SSSSSSSSSSSSSSSSSSSS 2627

Query: 288  SLTATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSINEVILSASGACKLIDSLH- 346
            S +++    S S S+  +  +P PA    Q+    ASP         +    K IDSL  
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRD 2687

Query: 347  ----SYCFSSRQNKSQVCCLREQVEKKNGELKSLRQRVSRSDSQVRKLQEKLDELRRVSV 402
                SY    R+  S     R+Q +  + E  S R +   S S   K        RR   
Sbjct: 2688 SRSLSYSPVERRRPSPQPSPRDQ-QSSSSERGSRRGQRGDSRSPSHK--------RRRET 2738

Query: 403  PYPSSLLSPSREPP 416
            P P  +   S   P
Sbjct: 2739 PSPRPMRHRSSRSP 2752



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 72/304 (23%), Positives = 100/304 (32%), Gaps = 27/304 (8%)

Query: 89  EKKRGAGGHGRTRRKDASKATGGVRGH-SSAATGRGAAGWSPSSSGNPMAKPESRRLKQA 147
           + KR +    R R +  + A    R H S++A    ++  S S S +  AK  +  L   
Sbjct: 235 KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGR 294

Query: 148 ALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSSIE 207
           +    +  R   +A   E    + +R      AT    S    E    D  ++SAT    
Sbjct: 295 SPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP--YEDKDKDKKEKSATRPSP 352

Query: 208 GGVTDKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEP 267
                 +G      TP        +   H  S     T      P  P       +D  P
Sbjct: 353 SPERSSTGPEPPAPTP-------LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405

Query: 268 SCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMS 327
             S   L        SPPS   T   +  S SP       +PKPA          +SP S
Sbjct: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPE------SPKPAPAPGSHREISSSPTS 459

Query: 328 INEVILSASGACKLIDSLHSYCFSSRQNKSQVCCLREQVEKKNGELKSLRQRVSRSDSQV 387
            N     + G  K  D  HS+  S R  +S     R     K G  +S R    R  S+ 
Sbjct: 460 KNR----SHGRAKR-DKSHSHTPSRRMGRS-----RSPATAKRGRSRS-RTPTKRGHSRS 508

Query: 388 RKLQ 391
           R  Q
Sbjct: 509 RSPQ 512



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 75/346 (21%), Positives = 132/346 (38%), Gaps = 40/346 (11%)

Query: 99  RTRRKDASKATGGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQA-----ALQGEA 153
           R+R +  ++ +G  R  + A  GR  +  +P+  G   ++  +RR  ++     A +G +
Sbjct: 634 RSRSRSPARRSGRSRSRTPARRGRSRSR-TPARRGRSRSRTPARRSGRSRSRTPARRGRS 692

Query: 154 TPRAAQEAASQEQAQ----QALERTPGD-GLATMVAGSQGKAEASATDAGDESATSSIEG 208
             R  +   S+ ++     ++  RTP   G +   +  + K+  S   +   S+    + 
Sbjct: 693 RSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKS 752

Query: 209 GVTDKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVP----REPIDRKRLKKD 264
            ++ +   S+     P S A   +    S S SS   +++   P    R    + + K  
Sbjct: 753 RISSRRSRSLSS---PRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR 809

Query: 265 VEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQSPSAPPADVTPKPATEAVQSEHSDAS 324
             P  S SS         SPP    + TP + S S S+P     PK  +     + S  S
Sbjct: 810 TPPRRSRSS--------SSPPPKQKSKTPSRQSHSSSSP----HPKVKSGTPPRQGSITS 857

Query: 325 PMSINEVILSASGACKLIDSLHSYCFSSRQNKSQVCCLREQVEKKNGELKSLRQRVSRSD 384
           P +  + +     +C   +S       SR      C        K+      RQ  SRS 
Sbjct: 858 PQANEQSVTPQRRSC--FESSPDPELKSRTPSRHSCSGSSPPRVKSS--TPPRQSPSRSS 913

Query: 385 SQVRKLQEKLDELRR----VSVPYPSSLLSPSREPPKMNPVVEPLS 426
           S   K++  +   +R     S P PS +   SR  P+ +  V P S
Sbjct: 914 SPQPKVKAIISPRQRSHSGSSSPSPSRV--TSRTTPRRSRSVSPCS 957


>gi|239752511 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 609

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 54/231 (23%), Positives = 88/231 (38%), Gaps = 30/231 (12%)

Query: 124 AAGWSPSSSGNPMAKPESRR--LKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLAT 181
           A G +   + + +AKP++ R    + A QG AT   A   A+++ A          G+A 
Sbjct: 268 AHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAQGVAN 327

Query: 182 MVA--------GSQGKA-EASATDAGDESATSSI------EGGVTDKSGISM-------- 218
             A         +QG A E +A    +E A   +       G V ++             
Sbjct: 328 EDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAH 387

Query: 219 ---DDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVE--PSCSGSS 273
              ++ T  G      I S+     +        S+PR  + R      +   P  S + 
Sbjct: 388 GIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRMSPTASLRTPPMASLTR 447

Query: 274 LGPDKGLAQSPPSSSLTATPQKPSQSPSAPPADVTPKPATEAVQSEHSDAS 324
             P   L++ PP++SLT TP + S + S P A +T  P T ++      AS
Sbjct: 448 RPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLTRTPPTASLTRSPPTAS 498


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 55/241 (22%), Positives = 82/241 (34%), Gaps = 15/241 (6%)

Query: 102 RKDASKATGGVRGHSSAATGRGAAGWS-----PSSSGNPMAKPESRRLKQAALQGEATPR 156
           R+D S  T G    + A   R AAG       P+ S  P    E  R   ++    +T  
Sbjct: 152 RRDTSGPTPGTPSPAMARRSR-AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 210

Query: 157 AAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDESATSS-IEGGVTDKSG 215
            +  A  +  A   L+R     L++        A +  +  G   A +   +        
Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270

Query: 216 ISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKD--VEPSCSGSS 273
           +     TPP   A   +G L S   ++      PS P  P   + L       PS + +S
Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS-PSAPPSLQTLPSPPATPPSQATTS 329

Query: 274 LGPDK-----GLAQSPPSSSLTATPQKPSQSPSAPPADVTPKPATEAVQSEHSDASPMSI 328
           LG            SPP S L   P +   + + PP    P P      S  +  SP + 
Sbjct: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389

Query: 329 N 329
           N
Sbjct: 390 N 390



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 58/249 (23%), Positives = 90/249 (36%), Gaps = 35/249 (14%)

Query: 109 TGGVRGHSSAATGRGAAGWSPS-----SSGNPMAKPESRRLKQAALQGEATPRAAQEAAS 163
           T G R   S+A+       SP+     S+G  + +P SR L  +A    +  R+   A  
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252

Query: 164 QEQAQQALERTPGDGLATM-----VAGSQGKAEASATDAGDESATSSIEGGVTDKSGISM 218
             +A     +    GL  +         +  A A    +    AT S     +  +  S+
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312

Query: 219 DDF-TPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPD 277
               +PP +   +   SL S +  + H+   PS P  P+          P+ +   L   
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSF-LPSPPLSPLATP--PPQAPPALALPPLQAP 369

Query: 278 KGLAQSPPSSSL-TATPQKPS-------------------QSPSAPPADVTPKP-ATEAV 316
                SPP S L T +PQ P+                   Q+P +PPA     P AT   
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429

Query: 317 QSEHSDASP 325
           Q+  S A+P
Sbjct: 430 QAPPSLAAP 438


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 50/203 (24%), Positives = 85/203 (41%), Gaps = 11/203 (5%)

Query: 110 GGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQ 169
           G + G +SAAT   AAG +  S G+P +   ++R  + +   E  PR  + ++S    ++
Sbjct: 156 GLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEGS---ERRPRRDRRSSSGRSKER 212

Query: 170 ALERTPGDGLATMVAGSQ-GKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGA 228
             E    DG      GS+  K+ +  + +G+E A  +  G  +   G          S +
Sbjct: 213 HREHRRRDG---QRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSS 269

Query: 229 CKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSC--SGSSLGPDKGLAQSPPS 286
            +      ++   +K ++E PS  +EP    R  K  EP       SL P  G   SP S
Sbjct: 270 SRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDK-TEPKAYRRRRSLSPLGGRDDSPVS 328

Query: 287 SSLTATPQKPSQSPSAPPADVTP 309
              + +  +  +SPS      +P
Sbjct: 329 HRASQS-LRSRKSPSPAGGGSSP 350


>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
          Length = 1452

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 50/203 (24%), Positives = 85/203 (41%), Gaps = 11/203 (5%)

Query: 110 GGVRGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQ 169
           G + G +SAAT   AAG +  S G+P +   ++R  + +   E  PR  + ++S    ++
Sbjct: 156 GLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEGS---ERRPRRDRRSSSGRSKER 212

Query: 170 ALERTPGDGLATMVAGSQ-GKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGA 228
             E    DG      GS+  K+ +  + +G+E A  +  G  +   G          S +
Sbjct: 213 HREHRRRDG---QRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSS 269

Query: 229 CKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSC--SGSSLGPDKGLAQSPPS 286
            +      ++   +K ++E PS  +EP    R  K  EP       SL P  G   SP S
Sbjct: 270 SRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDK-TEPKAYRRRRSLSPLGGRDDSPVS 328

Query: 287 SSLTATPQKPSQSPSAPPADVTP 309
              + +  +  +SPS      +P
Sbjct: 329 HRASQS-LRSRKSPSPAGGGSSP 350


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 48/205 (23%), Positives = 76/205 (37%), Gaps = 14/205 (6%)

Query: 123  GAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATM 182
            G  G  P        K + +  K  AL  E    A+QE++S++  +   E    +     
Sbjct: 935  GRPGTKPPKRDEERGKTQGKHRKSFALDSEGE-EASQESSSEKDEEDDEEDEEDEDREEA 993

Query: 183  VAGSQGKAEASATDAGDESATSSIEGGV---TDKSGISMDDFTPPGSGACKFIGSLHSYS 239
            V  +  K E   +D  DE + SS +  +   +D    S  D     S +     S  S S
Sbjct: 994  VDTT--KKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSS 1051

Query: 240  FSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQKPSQS 299
             SS  + E  S   E  +R        P+   S+  P + +    P+      P++ + S
Sbjct: 1052 SSSSSSSESSSEDEEEEER--------PAALPSASPPPREVPVPTPAPVEVPVPERVAGS 1103

Query: 300  PSAPPADVTPKPATEAVQSEHSDAS 324
            P  P  +    PA  A  +E S  S
Sbjct: 1104 PVTPLPEQEASPARPAGPTEESPPS 1128



 Score = 36.2 bits (82), Expect = 0.084
 Identities = 40/185 (21%), Positives = 63/185 (34%), Gaps = 19/185 (10%)

Query: 130 SSSGNPMAKPESRRLKQ-AALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQG 188
           SS G P     S    Q +A     T  + +   S+   Q A  R      +     S  
Sbjct: 267 SSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTA 326

Query: 189 KAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRER 248
            A  +A  A   +++SS+    +  S  S   F    +    +  S + Y    +HT   
Sbjct: 327 IAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQ---RHTSYP 383

Query: 249 PSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPS--SSLTATPQKPSQSPSAPPAD 306
           P         +R  ++  P    +    +    + PPS  S L   P +P+     PPA 
Sbjct: 384 P---------RRATREEPPGAPFA----ENTAERFPPSYTSYLPPEPSRPTDQDYRPPAS 430

Query: 307 VTPKP 311
             P P
Sbjct: 431 EAPPP 435



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 47/196 (23%), Positives = 62/196 (31%), Gaps = 25/196 (12%)

Query: 121 GRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLA 180
           G G  G  PS     +    S R    A  G   P    E+    Q      R     + 
Sbjct: 441 GGGGGGGGPSPEREEVRT--SPRPASPARSGSPAPETTNESVPFAQHSSLDSR-----IE 493

Query: 181 TMVAGSQGKAEASATDAGDESATSSIEGGVTDK-----SGISMDDFTPPGSGACKFIGSL 235
            ++   + K    A+D  +E   SS+  G  D      SG      TPP + A  F    
Sbjct: 494 MLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPA-NFEDVA 552

Query: 236 HSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPSSSLTATPQK 295
            + S     TRE P            K + +   S  S G D  ++      S    P  
Sbjct: 553 PTGSGEPGATRESP------------KANGQNQASPCSSGDDMEISDDDRGGSPPPAPTP 600

Query: 296 PSQSPSAPPADVTPKP 311
           P Q P  PP    P P
Sbjct: 601 PQQPPPPPPPPPPPPP 616


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 61/232 (26%), Positives = 86/232 (37%), Gaps = 25/232 (10%)

Query: 113 RGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALE 172
           R HSS  TG      SP+SS +P  + ES   +        TP     A +  +      
Sbjct: 267 RVHSS--TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 324

Query: 173 RTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFI 232
           R+PG    T          AS+T +G  S  S+I     D SG +        SG  +  
Sbjct: 325 RSPGSTPTT-------HFPASSTTSG-HSEKSTIFHSSPDASGTTPSSAHSTTSGVSEES 376

Query: 233 GSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPS-SSLTA 291
            + HS   S+  T    S     + +       EP+ S SS G  +    + PS    TA
Sbjct: 377 STSHSQPGSTHTTAFPDSTTTSGLSQ-------EPTTSHSSQGSTEATLDTTPSPPGTTA 429

Query: 292 TPQKPSQS----PSAPPADVTPKPATEAVQSEHS---DASPMSINEVILSAS 336
            P + S +    PS+ P       +T   +SE S    +SP S     L  S
Sbjct: 430 APVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGS 481


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 61/232 (26%), Positives = 86/232 (37%), Gaps = 25/232 (10%)

Query: 113 RGHSSAATGRGAAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALE 172
           R HSS  TG      SP+SS +P  + ES   +        TP     A +  +      
Sbjct: 161 RVHSS--TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 218

Query: 173 RTPGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFI 232
           R+PG    T          AS+T +G  S  S+I     D SG +        SG  +  
Sbjct: 219 RSPGSTPTT-------HFPASSTTSG-HSEKSTIFHSSPDASGTTPSSAHSTTSGVSEES 270

Query: 233 GSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGSSLGPDKGLAQSPPS-SSLTA 291
            + HS   S+  T    S     + +       EP+ S SS G  +    + PS    TA
Sbjct: 271 STSHSQPGSTHTTAFPDSTTTSGLSQ-------EPTTSHSSQGSTEATLDTTPSPPGTTA 323

Query: 292 TPQKPSQS----PSAPPADVTPKPATEAVQSEHS---DASPMSINEVILSAS 336
            P + S +    PS+ P       +T   +SE S    +SP S     L  S
Sbjct: 324 APVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGS 375


>gi|145199237 transcription elongation factor B polypeptide 3
           binding protein 1 [Homo sapiens]
          Length = 1221

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 77/344 (22%), Positives = 119/344 (34%), Gaps = 50/344 (14%)

Query: 89  EKKRGA--------GGHGRTRRKDASKATGGVRGHSSAATGRGAAGWSPSSSGNPMAKPE 140
           +KK GA        G  G+ + KD        RG           G   SS      +PE
Sbjct: 378 KKKTGAPPAPSCKDGAQGKDKTKDKG------RGRPVEKPRADKKGPQASSPRRKAERPE 431

Query: 141 SRRLKQAALQGEATPRAAQEAASQEQAQQALERTPGDGLATMVAGSQGKAEASATDAGDE 200
             + K ++    ATP A       ++  +    T GD        + G+         D 
Sbjct: 432 GTKKKPSS----ATPVATSGKGRPDRPARRPSPTSGDSRP-----AAGRGPPRPLQLPDR 482

Query: 201 SATSSIEGGVTDKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRER--PSVPRE-PID 257
            +T +  G + ++   S+D+     +   K     H+  F  +   E   P VP   P  
Sbjct: 483 KSTKAPSGKLVERKARSLDEGASQDAPKLKKRALSHADLFGDESEDEAAGPGVPSVWPSA 542

Query: 258 RKRLKKDVEPSCSGSSLG------PDKGLAQSPPSSSLTATPQKPSQSPSAPPADVTPKP 311
              L  D + S S SSLG      P K L  SPP S   ++    S S S+  ADV    
Sbjct: 543 LPSLSSDSD-SDSDSSLGFPEAQGPPKRLKASPPPSPAPSSSSSSSSSTSSAGADVDYSA 601

Query: 312 ATEAVQSEHSDASPMSINEVILSASGACKLIDSLHSYCFSSRQNKSQVCCLREQVEKKNG 371
             + V     D+ PM     I + S + K  D              +    R+  +++  
Sbjct: 602 LEKEVD---FDSDPMEECLRIFNESTSVKTED--------------RGRLARQPPKEEKS 644

Query: 372 ELKSLRQRVSRSDSQVRKLQEKLDELRRVSVPYPSSLLSPSREP 415
           E K L    +    Q R++     + + V  P     + P+R P
Sbjct: 645 EEKGLSGLTTLFPGQKRRISHLSKQGQEVEPPRRGPAVPPARPP 688


>gi|148806908 fibronectin type III domain containing 1 [Homo
           sapiens]
          Length = 1894

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 65/234 (27%), Positives = 95/234 (40%), Gaps = 48/234 (20%)

Query: 128 SPSSSGNPM--AKPESRR-------LKQAALQGEATPRAAQEAA--SQEQAQQALERTPG 176
           +P+SS +P   A P+ R        LK   L     PR  Q  A  ++E   Q+ E T  
Sbjct: 484 APASSQHPSVPASPQGRNAKDLLLDLKNKILANGGAPRKPQLRAKKAEELDLQSTEITGE 543

Query: 177 DGLATMVAGSQGKAEASATDAGDESAT---------SSIEGGVT---------------D 212
           + L     GS+  +  S +D  D+  T         S +  G T               D
Sbjct: 544 EEL-----GSREDSPMSPSDTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVD 598

Query: 213 KSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPIDRKRLKKDVEPSCSGS 272
           K G S+   T P  GA     +  ++  S++ T  RPS+P    D   +  D +    G 
Sbjct: 599 KPGFSLA--TQPRPGAPPSASASPAHHASTQGTSHRPSLPASLNDNDLVDSDEDERAVG- 655

Query: 273 SLGPDKGLAQSPPSSSLTATPQKPSQSPSAPPADVTP--KPATEAVQSEHSDAS 324
           SL P    AQ  P  +L+ + Q PS S     + V P  KPA+ A ++ HS A+
Sbjct: 656 SLHPKGAFAQ--PRPALSPSRQSPS-SVLRDRSSVHPGAKPASPARRTPHSGAA 706


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.127    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,278,215
Number of Sequences: 37866
Number of extensions: 1329766
Number of successful extensions: 10450
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 442
Number of HSP's that attempted gapping in prelim test: 8714
Number of HSP's gapped (non-prelim): 1926
length of query: 577
length of database: 18,247,518
effective HSP length: 108
effective length of query: 469
effective length of database: 14,157,990
effective search space: 6640097310
effective search space used: 6640097310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.