Search of human proteins with 31543385

Search of human proteins with 31543385

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31543385 choline phosphate cytidylyltransferase 1 alpha
[Homo sapiens]
         (367 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31543385 choline phosphate cytidylyltransferase 1 alpha [Homo...   748   0.0  
gi|253795514 choline phosphate cytidylyltransferase 1 beta isofo...   495   e-140
gi|21361202 choline phosphate cytidylyltransferase 1 beta isofor...   495   e-140
gi|253795516 choline phosphate cytidylyltransferase 1 beta isofo...   464   e-131
gi|4505651 phosphate cytidylyltransferase 2, ethanolamine [Homo ...   103   3e-22
gi|122937227 U2-associated SR140 protein [Homo sapiens]                36   0.048
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora...    36   0.062
gi|33188445 microfilament and actin filament cross-linker protei...    35   0.11 
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    34   0.24 
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    34   0.24 
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        34   0.24 
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca...    33   0.41 
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca...    33   0.41 
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca...    33   0.41 
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal...    33   0.41 
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     33   0.41 
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    33   0.41 
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    33   0.41 
gi|76563921 chromosome 18 open reading frame 21 [Homo sapiens]         33   0.41 
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    33   0.53 
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             33   0.53 
gi|5803145 ralA binding protein 1 [Homo sapiens]                       33   0.53 
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]              32   0.69 
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]             32   0.69 
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             32   0.69 
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    32   0.90 
gi|169217383 PREDICTED: similar to coiled-coil domain containing...    32   0.90 
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    32   0.90 
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    32   0.90 
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    32   0.90 

>gi|31543385 choline phosphate cytidylyltransferase 1 alpha [Homo
           sapiens]
          Length = 367

 Score =  748 bits (1931), Expect = 0.0
 Identities = 367/367 (100%), Positives = 367/367 (100%)

Query: 1   MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV 60
           MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV
Sbjct: 1   MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV 60

Query: 61  RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN 120
           RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN
Sbjct: 61  RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN 120

Query: 121 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD 180
           FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD
Sbjct: 121 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD 180

Query: 181 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY 240
           VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY
Sbjct: 181 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY 240

Query: 241 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK 300
           HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK
Sbjct: 241 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK 300

Query: 301 HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD 360
           HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD
Sbjct: 301 HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD 360

Query: 361 ISEDEED 367
           ISEDEED
Sbjct: 361 ISEDEED 367


>gi|253795514 choline phosphate cytidylyltransferase 1 beta isoform
           2 [Homo sapiens]
          Length = 351

 Score =  495 bits (1274), Expect = e-140
 Identities = 246/331 (74%), Positives = 279/331 (84%), Gaps = 8/331 (2%)

Query: 41  LRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAK 100
           L  PAPF+DE       P+ ++T+ +A  GTP +RPVRVYADGIFDLFHSGHARALMQAK
Sbjct: 23  LTAPAPFADETNCQCQAPHEKLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAK 82

Query: 101 NLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAE 160
            LFPN+YL+VGVCSD+LTH FKGFTVMNE ERY+A++HCRYVDEV+R+APWTLTPEFL +
Sbjct: 83  TLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEK 142

Query: 161 HRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRN 220
           H+IDFVAHDDIPYSSAGSDDVYKHIKEAGMF PTQRTEGISTSDIITRIVRDYDVYARRN
Sbjct: 143 HKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRN 202

Query: 221 LQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEE 280
           LQRGYTAKELNVSFINEK+Y  Q +VDK+K+KVK+VEE+SKEFV +VEEKS DLIQKWEE
Sbjct: 203 LQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEE 262

Query: 281 KSREFIGSFLEMFGPEGALKHMLKEGKGRMLQAISPKQSPSSSPTR----ERSPSPSFRW 336
           KSREFIG+FLE+FGP+GA K M +E   RMLQA+SPKQSP SSPTR     RSPSP+F W
Sbjct: 263 KSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPVSSPTRSRSPSRSPSPTFSW 322

Query: 337 PFSGKTSPPCSPANLSRHKAAAYDISEDEED 367
               KTSPP SP   S   A+   +SE +ED
Sbjct: 323 -LPLKTSPPSSPKAAS---ASISSMSEGDED 349


>gi|21361202 choline phosphate cytidylyltransferase 1 beta isoform 1
           [Homo sapiens]
          Length = 369

 Score =  495 bits (1274), Expect = e-140
 Identities = 246/331 (74%), Positives = 279/331 (84%), Gaps = 8/331 (2%)

Query: 41  LRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAK 100
           L  PAPF+DE       P+ ++T+ +A  GTP +RPVRVYADGIFDLFHSGHARALMQAK
Sbjct: 41  LTAPAPFADETNCQCQAPHEKLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAK 100

Query: 101 NLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAE 160
            LFPN+YL+VGVCSD+LTH FKGFTVMNE ERY+A++HCRYVDEV+R+APWTLTPEFL +
Sbjct: 101 TLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEK 160

Query: 161 HRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRN 220
           H+IDFVAHDDIPYSSAGSDDVYKHIKEAGMF PTQRTEGISTSDIITRIVRDYDVYARRN
Sbjct: 161 HKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRN 220

Query: 221 LQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEE 280
           LQRGYTAKELNVSFINEK+Y  Q +VDK+K+KVK+VEE+SKEFV +VEEKS DLIQKWEE
Sbjct: 221 LQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEE 280

Query: 281 KSREFIGSFLEMFGPEGALKHMLKEGKGRMLQAISPKQSPSSSPTR----ERSPSPSFRW 336
           KSREFIG+FLE+FGP+GA K M +E   RMLQA+SPKQSP SSPTR     RSPSP+F W
Sbjct: 281 KSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPVSSPTRSRSPSRSPSPTFSW 340

Query: 337 PFSGKTSPPCSPANLSRHKAAAYDISEDEED 367
               KTSPP SP   S   A+   +SE +ED
Sbjct: 341 -LPLKTSPPSSPKAAS---ASISSMSEGDED 367


>gi|253795516 choline phosphate cytidylyltransferase 1 beta isoform
           3 [Homo sapiens]
          Length = 330

 Score =  464 bits (1195), Expect = e-131
 Identities = 224/288 (77%), Positives = 253/288 (87%)

Query: 41  LRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAK 100
           L  PAPF+DE       P+ ++T+ +A  GTP +RPVRVYADGIFDLFHSGHARALMQAK
Sbjct: 41  LTAPAPFADETNCQCQAPHEKLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAK 100

Query: 101 NLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAE 160
            LFPN+YL+VGVCSD+LTH FKGFTVMNE ERY+A++HCRYVDEV+R+APWTLTPEFL +
Sbjct: 101 TLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEK 160

Query: 161 HRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRN 220
           H+IDFVAHDDIPYSSAGSDDVYKHIKEAGMF PTQRTEGISTSDIITRIVRDYDVYARRN
Sbjct: 161 HKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRN 220

Query: 221 LQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEE 280
           LQRGYTAKELNVSFINEK+Y  Q +VDK+K+KVK+VEE+SKEFV +VEEKS DLIQKWEE
Sbjct: 221 LQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEE 280

Query: 281 KSREFIGSFLEMFGPEGALKHMLKEGKGRMLQAISPKQSPSSSPTRER 328
           KSREFIG+FLE+FGP+GA K M +E   RMLQA+SPKQSP  S  R R
Sbjct: 281 KSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPLKSWARCR 328


>gi|4505651 phosphate cytidylyltransferase 2, ethanolamine [Homo
           sapiens]
          Length = 389

 Score =  103 bits (256), Expect = 3e-22
 Identities = 54/136 (39%), Positives = 81/136 (59%), Gaps = 2/136 (1%)

Query: 75  RPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYD 134
           R VRV+ DG +D+ H GH+  L QA+ +    YLIVGV +DE     KG  V  + ERY 
Sbjct: 21  RAVRVWCDGCYDMVHYGHSNQLRQARAM--GDYLIVGVHTDEEIAKHKGPPVFTQEERYK 78

Query: 135 AVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPT 194
            VQ  ++VDEVV  AP+  T E L ++  DF  H +    +    D Y+ +K+AG +   
Sbjct: 79  MVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTVDGRDTYEEVKQAGRYREC 138

Query: 195 QRTEGISTSDIITRIV 210
           +RT+G+ST+D++ R++
Sbjct: 139 KRTQGVSTTDLVGRML 154



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 56/156 (35%), Positives = 83/156 (53%), Gaps = 7/156 (4%)

Query: 79  VYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKG--FTVMNENERYDAV 136
           +Y  G FDLFH GH   L +   L    Y+I G+  D+  +++KG  + +MN +ER  +V
Sbjct: 216 IYVAGAFDLFHIGHVDFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSV 275

Query: 137 QHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAH--DDIPYSSAGSDDVYKHIKEAGMFAPT 194
             CRYV EVV  AP+ +T E L+  ++D V H   +I     GSD  Y+  K  G+F   
Sbjct: 276 LACRYVSEVVIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDP-YQEPKRRGIFRQI 334

Query: 195 QRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKEL 230
                ++T  I+ RI+ +   Y  RN ++   AKEL
Sbjct: 335 DSGSNLTTDLIVQRIITNRLEYEARNQKK--EAKEL 368


>gi|122937227 U2-associated SR140 protein [Homo sapiens]
          Length = 1029

 Score = 36.2 bits (82), Expect = 0.048
 Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 2/110 (1%)

Query: 254 KDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRMLQA 313
           + VE    + +Q+ +EK ++  ++ ++K +E + S  +    +       KE K R   +
Sbjct: 873 EQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRR--HS 930

Query: 314 ISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYDISE 363
            SP  S SSS  R +SPSP        + S   S  + S HK +  D+S+
Sbjct: 931 TSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSK 980


>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 1 [Homo
            sapiens]
          Length = 1834

 Score = 35.8 bits (81), Expect = 0.062
 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 20/148 (13%)

Query: 232  VSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLE 291
            +  + +++   Q+++++++K+  +   + +E  ++ EE+     +  EEK R+  G +  
Sbjct: 1612 LDLLQDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTK--RDAEEKRRQEEGYYSR 1669

Query: 292  MFGPEGALKHMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPP------ 345
            +   E   +    E   R+L+  +P       P     PSPS   P  G   PP      
Sbjct: 1670 L---EAERRRQHDEAARRLLEPEAPGLCRPPLPRDYEPPSPS---PAPGAPPPPPQRNAS 1723

Query: 346  ------CSPANLSRHKAAAYDISEDEED 367
                   SP +L   K  AY+  E+EED
Sbjct: 1724 YLKTQVLSPDSLFTAKFVAYNEEEEEED 1751


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 25/88 (28%), Positives = 47/88 (53%), Gaps = 11/88 (12%)

Query: 182  YKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYH 241
            YK   E+   +P +R   +S+SD IT+   D        L+  YTA    V+   +   +
Sbjct: 1357 YKAFVESQQKSPGKRRRMLSSSDAITQEFMD--------LRTRYTAL---VTLTTQHVKY 1405

Query: 242  LQERVDKVKKKVKDVEEKSKEFVQKVEE 269
            + + + +++++ K VEE+ +E V+KV+E
Sbjct: 1406 ISDALRRLEEEEKVVEEEKQEHVEKVKE 1433



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 1/115 (0%)

Query: 219  RNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKW 278
            +NL++ +T  +  V    +     QE++D+ +K V+  ++  KE    +      +  K 
Sbjct: 2235 QNLRKDFTELQKTVKEREKDASSCQEQLDEFRKLVRTFQKWLKETEGSIPPTETSMSAKE 2294

Query: 279  EEKSREFIGSFLEMFGPEGALKHMLKEGKGRMLQAISPKQSPSSSPTRERSPSPS 333
             EK  E + S L+ +  +G L   +   KG  L+ +  + +   S  +  S  PS
Sbjct: 2295 LEKQIEHLKSLLDDWASKGTLVEEI-NCKGTSLENLIMEITAPDSQGKTGSILPS 2348


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 33.9 bits (76), Expect = 0.24
 Identities = 18/48 (37%), Positives = 33/48 (68%), Gaps = 1/48 (2%)

Query: 237 EKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSRE 284
           EK   L+E +   ++K+++VEEK +E  +K++E+  + IQ+ EEK +E
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE-EKIQRQEEKIQE 480


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 33.9 bits (76), Expect = 0.24
 Identities = 18/48 (37%), Positives = 33/48 (68%), Gaps = 1/48 (2%)

Query: 237 EKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSRE 284
           EK   L+E +   ++K+++VEEK +E  +K++E+  + IQ+ EEK +E
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE-EKIQRQEEKIQE 480


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 33.9 bits (76), Expect = 0.24
 Identities = 25/99 (25%), Positives = 50/99 (50%), Gaps = 17/99 (17%)

Query: 238 KKYHLQERV-DKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPE 296
           KKY  + +V D++++K +D +++ ++F ++ E++        + +S    G   +   P 
Sbjct: 278 KKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRD-------KPRSTSPAG---QHHSPI 327

Query: 297 GALKHMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFR 335
            +  H      G  +Q  SP      SP R+R+PSPS++
Sbjct: 328 SSRHHSSSSQSGSSIQRHSP------SPRRKRTPSPSYQ 360


>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 1 [Homo sapiens]
          Length = 1075

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 7/49 (14%)

Query: 313 AISPKQSPSSSPTRERSPSPSFRW----PFSGKTSPPCSPANLSRHKAA 357
           ++SP+QSP  SP   RS      W    P SG +S P SP    RH +A
Sbjct: 234 SLSPRQSPCHSP---RSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSA 279


>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 4 [Homo sapiens]
          Length = 1045

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 7/49 (14%)

Query: 313 AISPKQSPSSSPTRERSPSPSFRW----PFSGKTSPPCSPANLSRHKAA 357
           ++SP+QSP  SP   RS      W    P SG +S P SP    RH +A
Sbjct: 234 SLSPRQSPCHSP---RSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSA 279


>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 3 [Homo sapiens]
          Length = 1065

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 7/49 (14%)

Query: 313 AISPKQSPSSSPTRERSPSPSFRW----PFSGKTSPPCSPANLSRHKAA 357
           ++SP+QSP  SP   RS      W    P SG +S P SP    RH +A
Sbjct: 234 SLSPRQSPCHSP---RSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSA 279


>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 2 [Homo sapiens]
          Length = 1068

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 7/49 (14%)

Query: 313 AISPKQSPSSSPTRERSPSPSFRW----PFSGKTSPPCSPANLSRHKAA 357
           ++SP+QSP  SP   RS      W    P SG +S P SP    RH +A
Sbjct: 234 SLSPRQSPCHSP---RSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSA 279


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 20/58 (34%), Positives = 35/58 (60%), Gaps = 9/58 (15%)

Query: 237 EKKYHLQERVDKVKKKVKDVEEKSKE----FVQKVEEKSI-----DLIQKWEEKSREF 285
           E++  LQ+ + +VK++V DV +KS E     +QK+ EK +     +L +K + + REF
Sbjct: 450 EERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREF 507



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 22/80 (27%), Positives = 47/80 (58%), Gaps = 8/80 (10%)

Query: 221  LQRGYTAKELNVSFINEK---KYHLQER-VDKVKKKVKDVEEKSKEFV----QKVEEKSI 272
            L +  +AKE ++  +NE+   K+  QE+ ++KVK+K K+++E  K+ +     K++++  
Sbjct: 927  LTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELE 986

Query: 273  DLIQKWEEKSREFIGSFLEM 292
            +   +  +K ++F    LEM
Sbjct: 987  NTALELSQKEKQFNAKMLEM 1006



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 2/38 (5%)

Query: 299 LKHMLKEGKGRMLQAISPKQ--SPSSSPTRERSPSPSF 334
           LK  + E + ++ QA++P Q  S SS+PTR RS + SF
Sbjct: 5   LKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSF 42


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 29/158 (18%)

Query: 137 QHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQR 196
           QHC   D V++    +L+   +AE    +   DD P                 +F+P  R
Sbjct: 230 QHCEPQDGVIKIKASSLSTYKIAEQDFSYFFPDDPP---------------TFIFSPANR 274

Query: 197 TEG-------ISTSDIIT--RIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVD 247
             G       IS  D +   + +  Y   A +   +    +E+  S   EK    +E+ D
Sbjct: 275 RRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMK-SLAFEKAKLKREKAD 333

Query: 248 KVKKKVKDVE--EKSKEFVQKVEEKSIDLIQKWEEKSR 283
            ++ K K+ E  EK +E ++K+ E+  + ++K EEK R
Sbjct: 334 ALEAKKKEKEDKEKKREELKKIVEE--ERLKKKEEKER 369


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
           a [Homo sapiens]
          Length = 1556

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 29/158 (18%)

Query: 137 QHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQR 196
           QHC   D V++    +L+   +AE    +   DD P                 +F+P  R
Sbjct: 230 QHCEPQDGVIKIKASSLSTYKIAEQDFSYFFPDDPP---------------TFIFSPANR 274

Query: 197 TEG-------ISTSDIIT--RIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVD 247
             G       IS  D +   + +  Y   A +   +    +E+  S   EK    +E+ D
Sbjct: 275 RRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMK-SLAFEKAKLKREKAD 333

Query: 248 KVKKKVKDVE--EKSKEFVQKVEEKSIDLIQKWEEKSR 283
            ++ K K+ E  EK +E ++K+ E+  + ++K EEK R
Sbjct: 334 ALEAKKKEKEDKEKKREELKKIVEE--ERLKKKEEKER 369


>gi|76563921 chromosome 18 open reading frame 21 [Homo sapiens]
          Length = 220

 Score = 33.1 bits (74), Expect = 0.41
 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 11/118 (9%)

Query: 238 KKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEG 297
           + Y L  +  K+ KK KD +      V  +  K+ +   K   KSR F+ S L+      
Sbjct: 78  RNYTLSFKEAKMVKKFKDSKS-----VLLITCKTCNRTVKHHGKSRSFV-STLKSNPATP 131

Query: 298 ALKHMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHK 355
             K  LK  + R     +P    S S  + +SP+  FR P SG++   CS  N S+ K
Sbjct: 132 TSKLSLKTPERR---TANPNHDMSGS--KGKSPASVFRTPTSGQSVSTCSSKNTSKTK 184


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 17/48 (35%), Positives = 32/48 (66%), Gaps = 1/48 (2%)

Query: 237 EKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSRE 284
           E+K   QE++ + ++K+++ EEK +E  +K+ E+  + I + EEK RE
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE-EKIWEQEEKIRE 603



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 17/48 (35%), Positives = 30/48 (62%), Gaps = 1/48 (2%)

Query: 237 EKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSRE 284
           ++K H QE++ K ++KV   EEK  +  +K+ E+  + + + EEK RE
Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE-EKMWRQEEKIRE 527



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 16/48 (33%), Positives = 31/48 (64%), Gaps = 1/48 (2%)

Query: 237 EKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSRE 284
           EK    +E++ + K+K+++ EEK  E  +K+ E+  +++Q+ EEK  E
Sbjct: 571 EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQE-EMMQEQEEKMWE 617



 Score = 28.5 bits (62), Expect = 10.0
 Identities = 23/112 (20%), Positives = 46/112 (41%), Gaps = 5/112 (4%)

Query: 180 DVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKK 239
           D +K   E         T+       I  + ++ D  +    +   T +EL      EK 
Sbjct: 169 DSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELK-----EKN 223

Query: 240 YHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLE 291
             LQE++  V+ +  +++   KE  +K+E   + L Q+  +   + +G  L+
Sbjct: 224 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 16/164 (9%)

Query: 179 DDVYKHIKEAGMFAPTQRTEGISTSDI---ITRIVRDYDVYARRNL--QRGYT---AKEL 230
           D   +H K  G+ A     + +    +   +T+   +Y    RRN   +RG     A+  
Sbjct: 450 DKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPS 509

Query: 231 NVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFL 290
               + EK+    E+ +K +++ KD EEK ++   K   K  D I    E++ E      
Sbjct: 510 QEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEE-----R 564

Query: 291 EMFGPEGALKHMLKEG--KGRMLQAISPKQSPSSSPTRERSPSP 332
           E   P G  K    +G  KGR+ ++++ + + +S+     +  P
Sbjct: 565 EQATPRGR-KTANSQGRRKGRITRSMTNEAAAASAAAAAATEEP 607


>gi|5803145 ralA binding protein 1 [Homo sapiens]
          Length = 655

 Score = 32.7 bits (73), Expect = 0.53
 Identities = 29/109 (26%), Positives = 53/109 (48%), Gaps = 3/109 (2%)

Query: 178 SDDVYKHIKEAGMFAPTQ-RTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFIN 236
           SDD   H K+ G F   + RTEG +     +           +  +  +  K+ + S   
Sbjct: 62  SDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKKK 121

Query: 237 EKKYHLQERVDKVK-KKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSRE 284
           EK + ++E+  + K K+ K  EEK KE   K +  + D++++W+EK ++
Sbjct: 122 EKDFKIKEKPKEEKHKEEKHKEEKHKEKKSK-DLTAADVVKQWKEKKKK 169


>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
          Length = 849

 Score = 32.3 bits (72), Expect = 0.69
 Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 21/114 (18%)

Query: 252 KVKDVEEKSKEFVQKVEEKSIDL------IQKWEEKSREF---IGSFLEMFGPEGALKHM 302
           K+++ EEK+ E  +K E++  D       +QK E K  E    + +F   FG   A  ++
Sbjct: 238 KLEEFEEKASELYKKFEKEFTDHQETQAELQKKEAKINELQAELQAFKSQFGALPADCNI 297

Query: 303 ----LKEGKGRMLQAISPKQS-------PSSSPTRERSPSPSFRWPFSGKTSPP 345
                KEG G    A+ P          P   P     P P  R PFSG   PP
Sbjct: 298 PLPPSKEG-GTGHSALPPPPPLPSGGGVPPPPPPPPPPPLPGMRMPFSGPVPPP 350


>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
          Length = 1193

 Score = 32.3 bits (72), Expect = 0.69
 Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 21/114 (18%)

Query: 252 KVKDVEEKSKEFVQKVEEKSIDL------IQKWEEKSREF---IGSFLEMFGPEGALKHM 302
           K+++ EEK+ E  +K E++  D       +QK E K  E    + +F   FG   A  ++
Sbjct: 501 KLEEFEEKASELYKKFEKEFTDHQETQAELQKKEAKINELQAELQAFKSQFGALPADCNI 560

Query: 303 ----LKEGKGRMLQAISPKQS-------PSSSPTRERSPSPSFRWPFSGKTSPP 345
                KEG G    A+ P          P   P     P P  R PFSG   PP
Sbjct: 561 PLPPSKEG-GTGHSALPPPPPLPSGGGVPPPPPPPPPPPLPGMRMPFSGPVPPP 613


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 32.3 bits (72), Expect = 0.69
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 7/99 (7%)

Query: 214 DVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSID 273
           D+YA+     G TA    ++ + EK + LQE+V ++ +K+K+  E  K+     +E   D
Sbjct: 548 DLYAKIQAGEGETAV---LNQLQEKNHTLQEQVTQLTEKLKNQSESHKQ----AQENLHD 600

Query: 274 LIQKWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRMLQ 312
            +Q+ +   R      L +      L   L E K ++ Q
Sbjct: 601 QVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQ 639


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 32.0 bits (71), Expect = 0.90
 Identities = 19/70 (27%), Positives = 39/70 (55%), Gaps = 1/70 (1%)

Query: 215 VYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDL 274
           ++ +  ++     +E    +  E+K H QE + + K+K+ + EEK ++  +KV  +  + 
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE-EK 518

Query: 275 IQKWEEKSRE 284
           I++ EEK RE
Sbjct: 519 IREQEEKIRE 528



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 15/48 (31%), Positives = 33/48 (68%), Gaps = 1/48 (2%)

Query: 237 EKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSRE 284
           EK+   +E++ K ++K+++ EEK +E  +K+ E+  + I++ EE ++E
Sbjct: 598 EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE-EKIREQEEMTQE 644



 Score = 28.5 bits (62), Expect = 10.0
 Identities = 23/112 (20%), Positives = 46/112 (41%), Gaps = 5/112 (4%)

Query: 180 DVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKK 239
           D +K   E         T+       I  + ++ D  +    +   T +EL      EK 
Sbjct: 169 DSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELK-----EKN 223

Query: 240 YHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLE 291
             LQE++  V+ +  +++   KE  +K+E   + L Q+  +   + +G  L+
Sbjct: 224 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275



 Score = 28.5 bits (62), Expect = 10.0
 Identities = 20/54 (37%), Positives = 33/54 (61%), Gaps = 6/54 (11%)

Query: 237 EKKYHLQERVDKVKKKVKDVEEKSKEFVQKV---EEK---SIDLIQKWEEKSRE 284
           EK    +E+V + ++K+++ EEK +E  +K+   EEK     + IQ+ EEK RE
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630


>gi|169217383 PREDICTED: similar to coiled-coil domain containing 29
           [Homo sapiens]
          Length = 185

 Score = 32.0 bits (71), Expect = 0.90
 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 8/120 (6%)

Query: 164 DFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQR 223
           DFV H+D+       D + K +K+      T   E +S+  +   + +D  V  +  L  
Sbjct: 13  DFVCHEDLKTDQLKMDILIKKLKQK-FDDLTPEEEAVSSKCV--NLAKDNQVIQQELLSM 69

Query: 224 GYTAKELNVSFINEKKYHLQERVDKVKKKVKD--VE-EKSKEFVQKVEEKSIDLIQKWEE 280
               +E     + E K  L+E +  +K  +++  VE  K +E+  + +E++I  ++K EE
Sbjct: 70  KKVQQECEK--LEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEE 127


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 32.0 bits (71), Expect = 0.90
 Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 6/118 (5%)

Query: 174 SSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVS 233
           SS GS   +  ++E   +  +Q+T+  +   + T+   D + ++ +N +  +   + + S
Sbjct: 852 SSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTK---DDNSFSDKNKEHSFFITDSDAS 908

Query: 234 ---FINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGS 288
              F  E+     +  +      KDVE   KE +QKV  + IDL ++ E++ +   G+
Sbjct: 909 GGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGN 966


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 32.0 bits (71), Expect = 0.90
 Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 6/118 (5%)

Query: 174 SSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVS 233
           SS GS   +  ++E   +  +Q+T+  +   + T+   D + ++ +N +  +   + + S
Sbjct: 852 SSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTK---DDNSFSDKNKEHSFFITDSDAS 908

Query: 234 ---FINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGS 288
              F  E+     +  +      KDVE   KE +QKV  + IDL ++ E++ +   G+
Sbjct: 909 GGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGN 966


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 32.0 bits (71), Expect = 0.90
 Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 6/118 (5%)

Query: 174 SSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVS 233
           SS GS   +  ++E   +  +Q+T+  +   + T+   D + ++ +N +  +   + + S
Sbjct: 852 SSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTK---DDNSFSDKNKEHSFFITDSDAS 908

Query: 234 ---FINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGS 288
              F  E+     +  +      KDVE   KE +QKV  + IDL ++ E++ +   G+
Sbjct: 909 GGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGN 966


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,141,110
Number of Sequences: 37866
Number of extensions: 767246
Number of successful extensions: 5665
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 5249
Number of HSP's gapped (non-prelim): 486
length of query: 367
length of database: 18,247,518
effective HSP length: 104
effective length of query: 263
effective length of database: 14,309,454
effective search space: 3763386402
effective search space used: 3763386402
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.