Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 31377777

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31377777 NK2 homeobox 8 [Homo sapiens]
         (239 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31377777 NK2 homeobox 8 [Homo sapiens]                             489   e-139
gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]   151   6e-37
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]   138   5e-33
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap...   127   7e-30
gi|157426823 NK2 homeobox 4 [Homo sapiens]                            127   7e-30
gi|118766339 thyroid transcription factor 1 isoform 1 [Homo sapi...   127   9e-30
gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]    127   9e-30
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap...   122   3e-28
gi|4502365 NK3 homeobox 2 [Homo sapiens]                               93   2e-19
gi|19923352 NK3 homeobox 1 [Homo sapiens]                              92   4e-19
gi|116805350 homeo box (H6 family) 1 [Homo sapiens]                    86   3e-17
gi|157743259 H6 family homeobox 3 [Homo sapiens]                       84   8e-17
gi|70608170 H6 family homeobox 2 [Homo sapiens]                        83   2e-16
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  80   2e-15
gi|4758168 distal-less homeobox 2 [Homo sapiens]                       79   3e-15
gi|118582284 msh homeobox 1 [Homo sapiens]                             79   5e-15
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]                   78   6e-15
gi|226437602 NK1 homeobox 2 [Homo sapiens]                             77   1e-14
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  77   1e-14
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  77   1e-14
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  77   1e-14
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  77   1e-14
gi|63054872 ladybird homeobox 1 [Homo sapiens]                         77   1e-14
gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]            77   1e-14
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]                77   1e-14
gi|4504465 homeobox B2 [Homo sapiens]                                  76   3e-14
gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens]            74   9e-14
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]              74   9e-14
gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]            74   1e-13
gi|147901462 brain specific homeobox [Homo sapiens]                    72   4e-13

>gi|31377777 NK2 homeobox 8 [Homo sapiens]
          Length = 239

 Score =  489 bits (1260), Expect = e-139
 Identities = 239/239 (100%), Positives = 239/239 (100%)

Query: 1   MATSGRLSFTVRSLLDLPEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLE 60
           MATSGRLSFTVRSLLDLPEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLE
Sbjct: 1   MATSGRLSFTVRSLLDLPEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLE 60

Query: 61  TSPPDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASL 120
           TSPPDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASL
Sbjct: 61  TSPPDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASL 120

Query: 121 LRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQP 180
           LRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQP
Sbjct: 121 LRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQP 180

Query: 181 CGGGGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAYQHLASPALVSWNW 239
           CGGGGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAYQHLASPALVSWNW
Sbjct: 181 CGGGGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAYQHLASPALVSWNW 239


>gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]
          Length = 273

 Score =  151 bits (381), Expect = 6e-37
 Identities = 103/254 (40%), Positives = 126/254 (49%), Gaps = 61/254 (24%)

Query: 3   TSGRLSFTVRSLLDLPE---QDAQHLPRREPEPRAPQP---------------------- 37
           T+ +  F+V+ +LDLP+   ++       E E   P+P                      
Sbjct: 4   TNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQGALDAVQSLPLKN 63

Query: 38  -------DPCAAWLDSERGHYPS---------SDESSLETSPPDSSQRPSARPASPGS-- 79
                  +P   WL S  G   S           +SS ++  P + + P     +PG   
Sbjct: 64  PFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGG 123

Query: 80  DAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKL 139
           DA K++KRRVLFSKAQT ELERRFRQQRYLSAPERE LASL+RLTPTQVKIWFQNHRYK+
Sbjct: 124 DAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKM 183

Query: 140 KRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCG 199
           KRARA    E   L +           RRV VPVLVRDG+PC            AQ+   
Sbjct: 184 KRARAEKGMEVTPLPSP----------RRVAVPVLVRDGKPC--------HALKAQDLAA 225

Query: 200 APPAAACPLPGYPA 213
           A   A  P   Y A
Sbjct: 226 ATFQAGIPFSAYSA 239


>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
          Length = 324

 Score =  138 bits (347), Expect = 5e-33
 Identities = 100/249 (40%), Positives = 120/249 (48%), Gaps = 46/249 (18%)

Query: 18  PEQDAQHLPRREPE-PRAPQPDPCAAWLDSERGHYPSSDES------------------- 57
           PE  A  LP    E  RAP P  CA+   +    YP +                      
Sbjct: 59  PEAAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQK 118

Query: 58  --SLETSPPDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPERE 115
              LE +  D+++RP AR         +R+K RVLFS+AQ  ELERRF+QQRYLSAPER+
Sbjct: 119 AVELEKTEADNAERPRAR---------RRRKPRVLFSQAQVYELERRFKQQRYLSAPERD 169

Query: 116 QLASLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLV 175
           QLAS+L+LT TQVKIWFQN RYK KR R     E   L         P   RR+ VPVLV
Sbjct: 170 QLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPP-----PPPPPARRIAVPVLV 224

Query: 176 RDGQPCGGGGGGEVGTAAAQEKCGAPPAAACPLPGYPAFG-----PG-SALGLFPAYQHL 229
           RDG+PC     G+    A     G  P      P YP +G     PG S    +PA    
Sbjct: 225 RDGKPC----LGDSAPYAPAYGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSP 280

Query: 230 ASPALVSWN 238
           A PA  + N
Sbjct: 281 AQPATAAAN 289


>gi|148746211 NK2 transcription factor related, locus 3 [Homo
           sapiens]
          Length = 364

 Score =  127 bits (320), Expect = 7e-30
 Identities = 87/206 (42%), Positives = 108/206 (52%), Gaps = 27/206 (13%)

Query: 31  EPRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAEKRKKRRVL 90
           EP+  + +P       +R       + SLET+    +   S RP         R+K RVL
Sbjct: 103 EPKEHEEEPEVV---RDRSQKSCQLKKSLETAGDCKAAEESERPKP-----RSRRKPRVL 154

Query: 91  FSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGAAES 150
           FS+AQ  ELERRF+QQRYLSAPERE LAS L+LT TQVKIWFQN RYK KR R       
Sbjct: 155 FSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQR------- 207

Query: 151 PDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAP---PAAACP 207
            D +     HA P   RRV VPVLVRDG+PC            + +  GAP    A+A  
Sbjct: 208 QDKSLELGAHAPPPPPRRVAVPVLVRDGKPC---------VTPSAQAYGAPYSVGASAYS 258

Query: 208 LPGYPAFGPGSALGLFPAYQHLASPA 233
              +PA+G G++     A    A+ A
Sbjct: 259 YNSFPAYGYGNSAAAAAAAAAAAAAA 284


>gi|157426823 NK2 homeobox 4 [Homo sapiens]
          Length = 354

 Score =  127 bits (320), Expect = 7e-30
 Identities = 77/149 (51%), Positives = 88/149 (59%), Gaps = 4/149 (2%)

Query: 81  AEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLK 140
           A  R+KRRVLFS+AQ  ELERRF+QQ+YLSAPERE LAS++ LTPTQVKIWFQNHRYK+K
Sbjct: 186 AAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMK 245

Query: 141 R-ARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEV-GTAAAQEKC 198
           R A+   A +             P   RRV VPVLV+DG+PC  G      G A  Q   
Sbjct: 246 RQAKDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPA 305

Query: 199 GAP-PAAACPLPGYPAF-GPGSALGLFPA 225
             P P      P  PA  GPG  L    A
Sbjct: 306 PTPAPELEELSPSPPALHGPGGGLAALDA 334


>gi|118766339 thyroid transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 401

 Score =  127 bits (319), Expect = 9e-30
 Identities = 96/247 (38%), Positives = 117/247 (47%), Gaps = 38/247 (15%)

Query: 18  PEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLET--SPPDSSQRPSARPA 75
           P QD        P      PDP    +    G     + S +    S  D S+  +  P+
Sbjct: 129 PYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAPLPS 188

Query: 76  SPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNH 135
           +P      R+KRRVLFS+AQ  ELERRF+QQ+YLSAPERE LAS++ LTPTQVKIWFQNH
Sbjct: 189 AP------RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH 242

Query: 136 RYKLKRARAPGAAESP------------DLAASAELHAAPGLLRRVVVPVLVRDGQPCGG 183
           RYK+KR     AA+                    +  A     RRV VPVLV+DG+PC  
Sbjct: 243 RYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQA 302

Query: 184 GGGGEVGTAA--------AQEKCGAPPAAACP---------LPGYPAFGPGSALGLFPAY 226
           G     G A+        AQ +  A  AAA           L  +P   PGSA       
Sbjct: 303 GAPAP-GAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLA 361

Query: 227 QHLASPA 233
            H ASPA
Sbjct: 362 HHAASPA 368


>gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]
          Length = 371

 Score =  127 bits (319), Expect = 9e-30
 Identities = 96/247 (38%), Positives = 117/247 (47%), Gaps = 38/247 (15%)

Query: 18  PEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLET--SPPDSSQRPSARPA 75
           P QD        P      PDP    +    G     + S +    S  D S+  +  P+
Sbjct: 99  PYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAPLPS 158

Query: 76  SPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNH 135
           +P      R+KRRVLFS+AQ  ELERRF+QQ+YLSAPERE LAS++ LTPTQVKIWFQNH
Sbjct: 159 AP------RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH 212

Query: 136 RYKLKRARAPGAAESP------------DLAASAELHAAPGLLRRVVVPVLVRDGQPCGG 183
           RYK+KR     AA+                    +  A     RRV VPVLV+DG+PC  
Sbjct: 213 RYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQA 272

Query: 184 GGGGEVGTAA--------AQEKCGAPPAAACP---------LPGYPAFGPGSALGLFPAY 226
           G     G A+        AQ +  A  AAA           L  +P   PGSA       
Sbjct: 273 GAPAP-GAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLA 331

Query: 227 QHLASPA 233
            H ASPA
Sbjct: 332 HHAASPA 338


>gi|210147470 NK2 transcription factor related, locus 6 [Homo
           sapiens]
          Length = 219

 Score =  122 bits (306), Expect = 3e-28
 Identities = 76/141 (53%), Positives = 82/141 (58%), Gaps = 24/141 (17%)

Query: 81  AEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLK 140
           A +R+K RVLFS+AQ L LERRF+QQRYLSAPERE LAS L+LT TQVKIWFQN RYK K
Sbjct: 47  ARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCK 106

Query: 141 RARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGA 200
           R R            S EL   P   RRV VPVLVRDG+PC G G               
Sbjct: 107 RQRQD---------KSLELAGHPLTPRRVAVPVLVRDGKPCLGPG--------------- 142

Query: 201 PPAAACPLPGYPAFGPGSALG 221
           P A A P P   A  P S  G
Sbjct: 143 PGAPAFPSPYSAAVSPYSCYG 163


>gi|4502365 NK3 homeobox 2 [Homo sapiens]
          Length = 333

 Score = 92.8 bits (229), Expect = 2e-19
 Identities = 51/103 (49%), Positives = 63/103 (61%), Gaps = 11/103 (10%)

Query: 77  PGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHR 136
           P +   ++K+ R  FS AQ  ELERRF  QRYLS PER  LA+ L+LT TQVKIWFQN R
Sbjct: 199 PAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRR 258

Query: 137 YKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQ 179
           YK KR +            +A+L A+    ++V V VLVRD Q
Sbjct: 259 YKTKRRQ-----------MAADLLASAPAAKKVAVKVLVRDDQ 290


>gi|19923352 NK3 homeobox 1 [Homo sapiens]
          Length = 234

 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 60/152 (39%), Positives = 78/152 (51%), Gaps = 20/152 (13%)

Query: 27  RREPEPRAPQPDPCAA---------WLDSERGHYPSSDESSLETSPP--------DSSQR 69
           +R+PEP  P+P+P             L +     P   E+  ET P         DS   
Sbjct: 51  QRDPEPE-PEPEPEGGRSRAGAQNDQLSTGPRAAPEEAETLAETEPERHLGSYLLDSENT 109

Query: 70  PSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVK 129
             A P  P +  + +K+ R  FS  Q +ELER+F  Q+YLSAPER  LA  L+LT TQVK
Sbjct: 110 SGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVK 169

Query: 130 IWFQNHRYKLKRARAPGAAESPDLAASAELHA 161
           IWFQN RYK KR +   ++E  DL   + L A
Sbjct: 170 IWFQNRRYKTKRKQL--SSELGDLEKHSSLPA 199


>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
          Length = 348

 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 77/212 (36%), Positives = 94/212 (44%), Gaps = 34/212 (16%)

Query: 32  PRAPQPDPC---AAWLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAEKRKKRR 88
           PR P P      AA L + RG    ++E+S     P ++          G    ++KK R
Sbjct: 152 PRGPGPGAVQREAAEL-AARGPAAGTEEASELAEVPAAAGETRG---GVGVGGGRKKKTR 207

Query: 89  VLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGAA 148
            +FS++Q  +LE  F  +RYLS+ ER  LA+ L+LT TQVKIWFQN R K KR  A    
Sbjct: 208 TVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLA---- 263

Query: 149 ESPDLAASAELHAA----PGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAPPAA 204
                   AEL AA    PG  R V VPVL  +  P     G              P A 
Sbjct: 264 --------AELEAASLSPPGAQRLVRVPVLYHESPPAAAAAG-------PPATLPFPLAP 308

Query: 205 ACPLPGYPAFGPGSALGLFPAYQHLASPALVS 236
           A P P  P  G   AL    AY   A PA  S
Sbjct: 309 AAPAPPPPLLGFSGAL----AYPLAAFPAAAS 336


>gi|157743259 H6 family homeobox 3 [Homo sapiens]
          Length = 357

 Score = 84.3 bits (207), Expect = 8e-17
 Identities = 72/206 (34%), Positives = 92/206 (44%), Gaps = 38/206 (18%)

Query: 27  RREPEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAE---- 82
           R  PEP   + DP    LDS+       +ES  E S  +    P A  AS G+ A     
Sbjct: 151 RDSPEPLL-KADPDHKELDSKSPDEIILEESDSEESKKEGEAAPGAAGASVGAAAATPGA 209

Query: 83  ----------------KRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPT 126
                           ++KK R +FS++Q  +LE  F  +RYLS+ ER  LA+ L LT T
Sbjct: 210 EDWKKGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTET 269

Query: 127 QVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGG 186
           QVKIWFQN R K KR  A       +L A+   HAA    R V VP+L  +     G   
Sbjct: 270 QVKIWFQNRRNKWKRQLA------AELEAANLSHAA--AQRIVRVPILYHENSAAEG--- 318

Query: 187 GEVGTAAAQEKCGAPPAAACPLPGYP 212
                 AA    GAP   + PL  +P
Sbjct: 319 ------AAAAAAGAPVPVSQPLLTFP 338


>gi|70608170 H6 family homeobox 2 [Homo sapiens]
          Length = 273

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 74/223 (33%), Positives = 100/223 (44%), Gaps = 46/223 (20%)

Query: 23  QHLPRRE-PEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQR-------PSARP 74
           QH P+ + P+   P P PC        G  P   E +   SP  S  +       P+  P
Sbjct: 70  QHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSP 129

Query: 75  ASPGSDAEK-----------RKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRL 123
            SPGS+  +           +KK R +FS++Q  +LE  F  +RYLS+ ER  LAS L+L
Sbjct: 130 -SPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQL 188

Query: 124 TPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGG 183
           T TQVK WFQN R K KR        S +L A+   HA+   L  V +P++ RD      
Sbjct: 189 TETQVKTWFQNRRNKWKRQL------SAELEAANMAHASAQTL--VSMPLVFRD------ 234

Query: 184 GGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAY 226
                    ++  +   P + A P P Y    PGS L   P Y
Sbjct: 235 ---------SSLLRVPVPRSLAFPAPLY---YPGSNLSALPLY 265


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 75/218 (34%), Positives = 98/218 (44%), Gaps = 28/218 (12%)

Query: 26  PRREPEPRAPQPDPCAAWLDSERGHYPSSDESS---LETSPPDSSQRPSARPASPGSDAE 82
           P R PEP + +  P     +S     P    ++     T+P  ++     +    GSD++
Sbjct: 34  PTRPPEPPSTRQRPPGPRENSPVAPGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSK 93

Query: 83  KRKKRRV--LFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLK 140
             K RR    F+  Q + LE +F+  RYLS  ER  LA  L LT TQVKIWFQN R K K
Sbjct: 94  SGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWK 153

Query: 141 RARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGA 200
           + + PGA    D +A       PG             G   G G  G +   +     GA
Sbjct: 154 K-QNPGA----DTSAPTGGGGGPG------------PGAGPGTGLPGGLSPLSPSPPMGA 196

Query: 201 PPAAACPLPGYPAFGPGSALGLFPAYQ--HLASPALVS 236
           P     P  GYPA GPG   GL  A Q   L+SPA++S
Sbjct: 197 PLGMHGP-AGYPAHGPG---GLVCAAQLPFLSSPAVLS 230


>gi|4758168 distal-less homeobox 2 [Homo sapiens]
          Length = 328

 Score = 79.0 bits (193), Expect = 3e-15
 Identities = 56/163 (34%), Positives = 76/163 (46%), Gaps = 16/163 (9%)

Query: 61  TSPPDSSQRPSARPASP-----GSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPERE 115
           TS   ++  P      P         +K +K R ++S  Q   L+RRF++ +YL+ PER 
Sbjct: 124 TSSSPANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERA 183

Query: 116 QLASLLRLTPTQVKIWFQNHRYKLKRARAPG---AAESPDLAASAELHAAPGLLRRVVVP 172
           +LA+ L LT TQVKIWFQN R K K+    G   + + P  +AS    + P     V  P
Sbjct: 184 ELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASASPPCASPP-----VSAP 238

Query: 173 VLVRDGQP---CGGGGGGEVGTAAAQEKCGAPPAAACPLPGYP 212
                G P    GGGG G  G+ A         AA+  L  YP
Sbjct: 239 ASWDFGVPQRMAGGGGPGSGGSGAGSSGSSPSSAASAFLGNYP 281


>gi|118582284 msh homeobox 1 [Homo sapiens]
          Length = 303

 Score = 78.6 bits (192), Expect = 5e-15
 Identities = 69/192 (35%), Positives = 86/192 (44%), Gaps = 51/192 (26%)

Query: 9   FTVRSLLDLPEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQ 68
           F+V  LL LPE DA  L + E  P  P+  P   W+ S R             SPP    
Sbjct: 118 FSVGGLLKLPE-DA--LVKAE-SPEKPERTP---WMQSPR------------FSPP---- 154

Query: 69  RPSARPASPGSDAEKRK---KRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTP 125
            P+ R + P     K K   K R  F+ AQ L LER+FRQ++YLS  ER + +S L LT 
Sbjct: 155 -PARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTE 213

Query: 126 TQVKIWFQNHRYKLKRARAP------------------------GAAESPDLAASAELHA 161
           TQVKIWFQN R K KR +                          G   +   AA A L+ 
Sbjct: 214 TQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYG 273

Query: 162 APGLLRRVVVPV 173
           A G  +R  +PV
Sbjct: 274 ASGPFQRAALPV 285


>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
          Length = 284

 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 54/138 (39%), Positives = 68/138 (49%), Gaps = 10/138 (7%)

Query: 43  WLDSERGHYPSSDESSLETSPPDSSQR---PSARPASPGSDAEKRKKRRVLFSKAQTLEL 99
           W+DS R    + D  +   SP   ++R   P      P     KRKK R  FS++Q LEL
Sbjct: 120 WMDSGRRF--AKDRLTAALSPFSGTRRIGHPYQNRTPP-----KRKKPRTSFSRSQVLEL 172

Query: 100 ERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAEL 159
           ERRF +Q+YL++ ER  LA  LR+T  QVK WFQN R K +R  A         A    L
Sbjct: 173 ERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLL 232

Query: 160 HAAPGLLRRVVVPVLVRD 177
           H     L R + P L  D
Sbjct: 233 HLQQDALPRPLRPPLPPD 250



 Score = 27.7 bits (60), Expect = 9.2
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 4/54 (7%)

Query: 182 GGGGGGEVGTAAAQEKCGA---PPAAACPLPGYPAFGPGSALGLFPAYQHLASP 232
           GG G GE G  +      +   P  +  PLPG    GPG  + + PA++ L  P
Sbjct: 40  GGQGHGENGAFSGGYHGASGYGPAGSLAPLPGSSGVGPGGVIRV-PAHRPLPVP 92


>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 70/220 (31%), Positives = 94/220 (42%), Gaps = 46/220 (20%)

Query: 19  EQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPP--DSSQRP-SARPA 75
           E+DA+       +PR P+    AA L       P +   +L +  P  D    P  + P 
Sbjct: 92  EEDAE-------DPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPG 144

Query: 76  SPGSDAEKRKK----------RRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTP 125
           SPGS   +R++           R  F+  Q + LE +FR  RYLS  ER  LA  L LT 
Sbjct: 145 SPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTE 204

Query: 126 TQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGG 185
           TQVKIWFQN R K K+ + PGA  +  +   A    A G                 GGGG
Sbjct: 205 TQVKIWFQNRRTKWKK-QNPGADGAAQVGGGAPQPGAAG-----------------GGGG 246

Query: 186 GGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPA 225
           GG  G+       G P   A     +P++   +   LFP+
Sbjct: 247 GGSGGSP------GPPGTGALHFQTFPSYSAANV--LFPS 278



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 50/186 (26%), Positives = 68/186 (36%), Gaps = 65/186 (34%)

Query: 6   RLSFTVRSLLDLPEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPPD 65
           ++SF+V  +LD  +     LP   P PR  +     +  + E G   SS +   +   PD
Sbjct: 17  KISFSVLDILDPQKFTRAALPAVRPAPREAR----KSLAEVEAGKDASSRDPVRQLETPD 72

Query: 66  SSQRPSARPASP--GSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRL 123
           ++  P A  ASP  GS+AE+           +  E  RR R         RE+ A LL  
Sbjct: 73  AA-GPGAGQASPLEGSEAEEE----------EDAEDPRRPRL--------RERAARLL-- 111

Query: 124 TPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGG 183
                                PG A SPD  A A                 +  G+PC  
Sbjct: 112 ---------------------PGLARSPDAPAGA-----------------LASGEPCED 133

Query: 184 GGGGEV 189
           GGGG V
Sbjct: 134 GGGGPV 139


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 70/220 (31%), Positives = 94/220 (42%), Gaps = 46/220 (20%)

Query: 19  EQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPP--DSSQRP-SARPA 75
           E+DA+       +PR P+    AA L       P +   +L +  P  D    P  + P 
Sbjct: 114 EEDAE-------DPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPG 166

Query: 76  SPGSDAEKRKK----------RRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTP 125
           SPGS   +R++           R  F+  Q + LE +FR  RYLS  ER  LA  L LT 
Sbjct: 167 SPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTE 226

Query: 126 TQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGG 185
           TQVKIWFQN R K K+ + PGA  +  +   A    A G                 GGGG
Sbjct: 227 TQVKIWFQNRRTKWKK-QNPGADGAAQVGGGAPQPGAAG-----------------GGGG 268

Query: 186 GGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPA 225
           GG  G+       G P   A     +P++   +   LFP+
Sbjct: 269 GGSGGSP------GPPGTGALHFQTFPSYSAANV--LFPS 300



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 48/187 (25%), Positives = 66/187 (35%), Gaps = 45/187 (24%)

Query: 6   RLSFTVRSLLDLPEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDE--SSLETSP 63
           ++SF+V  +LD  +     LP   P PR  +     +  + E G   SS +    LET  
Sbjct: 17  KISFSVLDILDPQKFTRAALPAVRPAPREAR----KSLAEVEAGKDASSRDPVRQLETPG 72

Query: 64  PDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRL 123
              +     R A P   ++ R        +A  LE           S  E E+ A   R 
Sbjct: 73  QGFAASLLTRQAHPHHSSDARDAAGPGAGQASPLE----------GSEAEEEEDAEDPR- 121

Query: 124 TPTQVKIWFQNHRYKLKRAR-APGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCG 182
                       R + + AR  PG A SPD  A A                 +  G+PC 
Sbjct: 122 ----------RPRLRERAARLLPGLARSPDAPAGA-----------------LASGEPCE 154

Query: 183 GGGGGEV 189
            GGGG V
Sbjct: 155 DGGGGPV 161


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 75/213 (35%), Positives = 93/213 (43%), Gaps = 37/213 (17%)

Query: 28  REPEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAEKRKKR 87
           RE  P AP P   AA                  T+P  ++     +    GSD++  K R
Sbjct: 616 RENSPVAPGPPGGAA------------APGGAGTTPQGTATAAKPKRKRTGSDSKSGKPR 663

Query: 88  RV--LFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAP 145
           R    F+  Q + LE +F+  RYLS  ER  LA  L LT TQVKIWFQN R K K+ + P
Sbjct: 664 RARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK-QNP 722

Query: 146 GAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAPPAAA 205
           GA    D +A       PG             G   G G  G +   +     GAP    
Sbjct: 723 GA----DTSAPTGGGGGPG------------PGAGPGTGLPGGLSPLSPSPPMGAPLGMH 766

Query: 206 CPLPGYPAFGPGSALGLFPAYQ--HLASPALVS 236
            P  GYPA GPG   GL  A Q   L+SPA++S
Sbjct: 767 GP-AGYPAHGPG---GLVCAAQLPFLSSPAVLS 795


>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 70/220 (31%), Positives = 94/220 (42%), Gaps = 46/220 (20%)

Query: 19  EQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPP--DSSQRP-SARPA 75
           E+DA+       +PR P+    AA L       P +   +L +  P  D    P  + P 
Sbjct: 114 EEDAE-------DPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPG 166

Query: 76  SPGSDAEKRKK----------RRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTP 125
           SPGS   +R++           R  F+  Q + LE +FR  RYLS  ER  LA  L LT 
Sbjct: 167 SPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTE 226

Query: 126 TQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGG 185
           TQVKIWFQN R K K+ + PGA  +  +   A    A G                 GGGG
Sbjct: 227 TQVKIWFQNRRTKWKK-QNPGADGAAQVGGGAPQPGAAG-----------------GGGG 268

Query: 186 GGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPA 225
           GG  G+       G P   A     +P++   +   LFP+
Sbjct: 269 GGSGGSP------GPPGTGALHFQTFPSYSAANV--LFPS 300



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 48/187 (25%), Positives = 66/187 (35%), Gaps = 45/187 (24%)

Query: 6   RLSFTVRSLLDLPEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDE--SSLETSP 63
           ++SF+V  +LD  +     LP   P PR  +     +  + E G   SS +    LET  
Sbjct: 17  KISFSVLDILDPQKFTRAALPAVRPAPREAR----KSLAEVEAGKDASSRDPVRQLETPG 72

Query: 64  PDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRL 123
              +     R A P   ++ R        +A  LE           S  E E+ A   R 
Sbjct: 73  QGFAASLLTRQAHPHHSSDARDAAGPGAGQASPLE----------GSEAEEEEDAEDPR- 121

Query: 124 TPTQVKIWFQNHRYKLKRAR-APGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCG 182
                       R + + AR  PG A SPD  A A                 +  G+PC 
Sbjct: 122 ----------RPRLRERAARLLPGLARSPDAPAGA-----------------LASGEPCE 154

Query: 183 GGGGGEV 189
            GGGG V
Sbjct: 155 DGGGGPV 161


>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 70/220 (31%), Positives = 94/220 (42%), Gaps = 46/220 (20%)

Query: 19  EQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDESSLETSPP--DSSQRP-SARPA 75
           E+DA+       +PR P+    AA L       P +   +L +  P  D    P  + P 
Sbjct: 114 EEDAE-------DPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGGPVRSPPG 166

Query: 76  SPGSDAEKRKK----------RRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTP 125
           SPGS   +R++           R  F+  Q + LE +FR  RYLS  ER  LA  L LT 
Sbjct: 167 SPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTE 226

Query: 126 TQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGG 185
           TQVKIWFQN R K K+ + PGA  +  +   A    A G                 GGGG
Sbjct: 227 TQVKIWFQNRRTKWKK-QNPGADGAAQVGGGAPQPGAAG-----------------GGGG 268

Query: 186 GGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPA 225
           GG  G+       G P   A     +P++   +   LFP+
Sbjct: 269 GGSGGSP------GPPGTGALHFQTFPSYSAANV--LFPS 300



 Score = 29.3 bits (64), Expect = 3.2
 Identities = 48/187 (25%), Positives = 66/187 (35%), Gaps = 45/187 (24%)

Query: 6   RLSFTVRSLLDLPEQDAQHLPRREPEPRAPQPDPCAAWLDSERGHYPSSDE--SSLETSP 63
           ++SF+V  +LD  +     LP   P PR  +     +  + E G   SS +    LET  
Sbjct: 17  KISFSVLDILDPQKFTRAALPAVRPAPREAR----KSLAEVEAGKDASSRDPVRQLETPG 72

Query: 64  PDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRL 123
              +     R A P   ++ R        +A  LE           S  E E+ A   R 
Sbjct: 73  QGFAASLLTRQAHPHHSSDARDAAGPGAGQASPLE----------GSEAEEEEDAEDPR- 121

Query: 124 TPTQVKIWFQNHRYKLKRAR-APGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCG 182
                       R + + AR  PG A SPD  A A                 +  G+PC 
Sbjct: 122 ----------RPRLRERAARLLPGLARSPDAPAGA-----------------LASGEPCE 154

Query: 183 GGGGGEV 189
            GGGG V
Sbjct: 155 DGGGGPV 161


>gi|63054872 ladybird homeobox 1 [Homo sapiens]
          Length = 281

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 56/152 (36%), Positives = 74/152 (48%), Gaps = 11/152 (7%)

Query: 82  EKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKR 141
           +KR+K R  F+  Q  ELE+RF  Q+YLS  +R+Q+A  L LT  QV  WFQN R KLKR
Sbjct: 123 KKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKR 182

Query: 142 ARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAP 201
                 A+      SA+     G +  V +  L ++ +   GGGG   G   A+ + G+P
Sbjct: 183 DLEEMKAD----VESAKKLGPSGQMDIVALAELEQNSEATAGGGG---GCGRAKSRPGSP 235

Query: 202 PAAACPLPGYPAFGPGSALGLFPAYQHLASPA 233
                  PG P      AL L PA      PA
Sbjct: 236 VLP----PGAPKAPGAGALQLSPASPLTDQPA 263


>gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
          Length = 255

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 59/168 (35%), Positives = 78/168 (46%), Gaps = 25/168 (14%)

Query: 43  WLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAEKR-----------------K 85
           +++S   H  S   SS++ S P S+    +R   PG+D+EK                  +
Sbjct: 71  YVNSVSSHASSPYISSVQ-SYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIR 129

Query: 86  KRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAP 145
           K R ++S  Q   L RRF+Q +YL+ PER +LA+ L LT TQVKIWFQN R K K+    
Sbjct: 130 KPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQ 189

Query: 146 GAA--ESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGT 191
           G A  E   LA    L A         VP         G G GG  G+
Sbjct: 190 GGAALEGSALANGRALSAG-----SPPVPPGWNPNSSSGKGSGGNAGS 232


>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
          Length = 411

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 67/180 (37%), Positives = 85/180 (47%), Gaps = 25/180 (13%)

Query: 61  TSPPDSSQRPSARPASPGSDAEKRKKRRV--LFSKAQTLELERRFRQQRYLSAPEREQLA 118
           T+P  ++     +    GSD++  K RR    F+  Q + LE +F+  RYLS  ER  LA
Sbjct: 234 TTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLA 293

Query: 119 SLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDG 178
             L LT TQVKIWFQN R K K+ + PGA    D +A       PG             G
Sbjct: 294 LSLSLTETQVKIWFQNRRTKWKK-QNPGA----DTSAPTGGGGGPG------------PG 336

Query: 179 QPCGGGGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALGLFPAYQ--HLASPALVS 236
              G G  G +   +     GAP     P  GYPA GPG   GL  A Q   L+SPA++S
Sbjct: 337 AGPGTGLPGGLSPLSPSPPMGAPLGMHGP-AGYPAHGPG---GLVCAAQLPFLSSPAVLS 392


>gi|4504465 homeobox B2 [Homo sapiens]
          Length = 356

 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 70/222 (31%), Positives = 91/222 (40%), Gaps = 36/222 (16%)

Query: 20  QDAQHLPRREPEPR-APQPDPCAAWLDSERGHYPSSDESSLETSP-PDSSQRPSARPASP 77
           +D   LP   P P  A  P P   W+  ++    +   S   TSP P +S  P++   SP
Sbjct: 73  EDGPALPPPPPPPLPAAPPAPEFPWMKEKKS---AKKPSQSATSPSPAASAVPASGVGSP 129

Query: 78  G-------SDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKI 130
                   +     ++ R  ++  Q LELE+ F   +YL  P R ++A+LL LT  QVK+
Sbjct: 130 ADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKV 189

Query: 131 WFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVG 190
           WFQN R K KR       E PD        A PG L  +  P       P     GG   
Sbjct: 190 WFQNRRMKHKRQTQ--HREPPDGEP-----ACPGALEDICDPAEEPAASP-----GGPSA 237

Query: 191 TAAAQEKCGAPPAA------------ACPLPGYPAFGPGSAL 220
           + AA E C  PP              A  L G  A  PG AL
Sbjct: 238 SRAAWEACCHPPEVVPGALSADPRPLAVRLEGAGASSPGCAL 279


>gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens]
          Length = 168

 Score = 74.3 bits (181), Expect = 9e-14
 Identities = 61/180 (33%), Positives = 81/180 (45%), Gaps = 42/180 (23%)

Query: 63  PPDSSQ-RPSARPAS--PGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLAS 119
           PPDS + R S  P+   P + A+K +K R ++S  Q   L +RF+  +YL+ PER QLA+
Sbjct: 21  PPDSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAA 80

Query: 120 LLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQ 179
            L LT TQVKIWFQN R K K+                       LL+           Q
Sbjct: 81  QLGLTQTQVKIWFQNKRSKYKK-----------------------LLK-----------Q 106

Query: 180 PCGGGGGGEVGTAAAQEKCGAPPAAACPLP---GYPAFGPGSALGLFPAYQHLASPALVS 236
             GG  G   G   +   C  P  +   LP     P  G G++ G +  YQH +S  L S
Sbjct: 107 NSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAW--YQHHSSDVLAS 164


>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
          Length = 348

 Score = 74.3 bits (181), Expect = 9e-14
 Identities = 41/104 (39%), Positives = 55/104 (52%), Gaps = 6/104 (5%)

Query: 44  LDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRF 103
           L  +  H       +LE +PP S    S       +   K ++RR  F+  Q LELE+ F
Sbjct: 213 LTGQAAHKEEDPGHALEETPPSSGAAGST------TSTGKNRRRRTAFTSEQLLELEKEF 266

Query: 104 RQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGA 147
             ++YLS  ER Q+A  L+L+  QVKIWFQN R K KR +A  A
Sbjct: 267 HCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNA 310


>gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]
          Length = 240

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 60/184 (32%), Positives = 80/184 (43%), Gaps = 41/184 (22%)

Query: 56  ESSLETSPPDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPERE 115
           E   ++  P  S  PS R   P + A+K +K R ++S  Q   L +RF+  +YL+ PER 
Sbjct: 91  ELEADSEKPRLSPEPSER--RPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERA 148

Query: 116 QLASLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLV 175
           QLA+ L LT TQVKIWFQN R K K+                       LL+        
Sbjct: 149 QLAAQLGLTQTQVKIWFQNKRSKYKK-----------------------LLK-------- 177

Query: 176 RDGQPCGGGGGGEVGTAAAQEKCGAPPAAACPLP---GYPAFGPGSALGLFPAYQHLASP 232
              Q  GG  G   G   +   C  P  +   LP     P  G G++ G +  YQH +S 
Sbjct: 178 ---QNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAW--YQHHSSD 232

Query: 233 ALVS 236
            L S
Sbjct: 233 VLAS 236


>gi|147901462 brain specific homeobox [Homo sapiens]
          Length = 233

 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 48/121 (39%), Positives = 64/121 (52%), Gaps = 13/121 (10%)

Query: 83  KRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKR- 141
           +R+K R +FS +Q   LE+RF  QRYLS PER +LA+ L L+ TQVK WFQN R K K+ 
Sbjct: 109 RRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQ 168

Query: 142 -------ARAPGAAESPDLAASAELHAAPGLLRRVVVP----VLVRDGQPCGGGGGGEVG 190
                   +AP   ESP+  +     AA     R+ +P    VL         G  GE+G
Sbjct: 169 LRKSQDEPKAPDGPESPE-GSPRGSEAATAAEARLSLPAGPFVLTEPEDEVDIGDEGELG 227

Query: 191 T 191
           +
Sbjct: 228 S 228


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,223,286
Number of Sequences: 37866
Number of extensions: 725969
Number of successful extensions: 6685
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 332
Number of HSP's successfully gapped in prelim test: 278
Number of HSP's that attempted gapping in prelim test: 5680
Number of HSP's gapped (non-prelim): 1215
length of query: 239
length of database: 18,247,518
effective HSP length: 99
effective length of query: 140
effective length of database: 14,498,784
effective search space: 2029829760
effective search space used: 2029829760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press