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Search of human proteins with 31317301
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein
isoform 1 [Homo sapiens]
(506 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein i... 1003 0.0
gi|205277334 nitric oxide synthase 1 (neuronal) adaptor protein ... 386 e-107
gi|132626790 low density lipoprotein receptor adaptor protein 1 ... 74 3e-13
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom... 70 3e-12
gi|140161500 ankyrin repeat and sterile alpha motif domain conta... 57 3e-08
gi|50511947 cajalin 2 isoform b [Homo sapiens] 57 5e-08
gi|50511945 cajalin 2 isoform a [Homo sapiens] 57 5e-08
gi|10047134 cajalin 2 isoform c [Homo sapiens] 57 5e-08
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] 54 3e-07
gi|54144629 numb homolog isoform 4 [Homo sapiens] 51 2e-06
gi|20070356 numb homolog isoform 3 [Homo sapiens] 51 2e-06
gi|54144627 numb homolog isoform 2 [Homo sapiens] 50 5e-06
gi|54144625 numb homolog isoform 1 [Homo sapiens] 50 5e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 44 3e-04
gi|169211037 PREDICTED: similar to mitogen-activated protein kin... 43 6e-04
gi|239740950 PREDICTED: similar to mitogen-activated protein kin... 43 6e-04
gi|4885433 mitogen-activated protein kinase 8 interacting protei... 41 0.003
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 38 0.019
gi|66934969 runt-related transcription factor 2 isoform c [Homo ... 38 0.025
gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens] 38 0.025
gi|41406089 SRY-box 13 [Homo sapiens] 38 0.025
gi|226442791 runt-related transcription factor 2 isoform b [Homo... 37 0.032
gi|226442783 runt-related transcription factor 2 isoform a [Homo... 37 0.032
gi|226246533 TOX high mobility group box family member 3 isoform... 37 0.032
gi|226054295 TOX high mobility group box family member 3 isoform... 37 0.032
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 37 0.032
gi|23503317 coiled-coil domain containing 96 [Homo sapiens] 37 0.032
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 37 0.042
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 36 0.072
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 36 0.072
>gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein
isoform 1 [Homo sapiens]
Length = 506
Score = 1003 bits (2593), Expect = 0.0
Identities = 506/506 (100%), Positives = 506/506 (100%)
Query: 1 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY 60
MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY
Sbjct: 1 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY 60
Query: 61 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS 120
EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS
Sbjct: 61 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS 120
Query: 121 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA 180
HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA
Sbjct: 121 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA 180
Query: 181 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL 240
DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL
Sbjct: 181 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL 240
Query: 241 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL 300
DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL
Sbjct: 241 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL 300
Query: 301 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE 360
QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE
Sbjct: 301 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE 360
Query: 361 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG 420
LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG
Sbjct: 361 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG 420
Query: 421 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS 480
RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS
Sbjct: 421 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS 480
Query: 481 QEELPRLLNVLQRQELGDGLDDEIAV 506
QEELPRLLNVLQRQELGDGLDDEIAV
Sbjct: 481 QEELPRLLNVLQRQELGDGLDDEIAV 506
>gi|205277334 nitric oxide synthase 1 (neuronal) adaptor protein
isoform 2 [Homo sapiens]
Length = 211
Score = 386 bits (991), Expect = e-107
Identities = 194/194 (100%), Positives = 194/194 (100%)
Query: 313 QVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQ 372
QVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQ
Sbjct: 18 QVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQ 77
Query: 373 DSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFR 432
DSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFR
Sbjct: 78 DSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFR 137
Query: 433 FLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQ 492
FLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQ
Sbjct: 138 FLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQ 197
Query: 493 RQELGDGLDDEIAV 506
RQELGDGLDDEIAV
Sbjct: 198 RQELGDGLDDEIAV 211
>gi|132626790 low density lipoprotein receptor adaptor protein 1
[Homo sapiens]
Length = 308
Score = 73.9 bits (180), Expect = 3e-13
Identities = 83/307 (27%), Positives = 126/307 (41%), Gaps = 44/307 (14%)
Query: 2 PSKTKYNLVDDGHDLRIPLHNEDAFQ---HGICFEAKYVGSLDVPRPNSRVEIVAAMRRI 58
PS K + G ++P + D + G+ F KY+G V +P AA++RI
Sbjct: 15 PSLAKQSWGGGGRHRKLPENWTDTRETLLEGMLFSLKYLGMTLVEQPKGEELSAAAIKRI 74
Query: 59 RYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFY 118
KA K +KV++ VS G+ + T + + L+ IYRI Y
Sbjct: 75 VATAKASGKKLQKVTLKVSPRGIIL----------------TDNLTNQLIENVSIYRISY 118
Query: 119 VSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCH---KLSLQH 175
+ D K+F+YIA+ + C+ F K+ A + TV QAF+V ++S +
Sbjct: 119 CTADKMHDKVFAYIAQSQHNQSLECHAFLCTKRKMAQAVTLTVAQAFKVAFEFWQVSKEE 178
Query: 176 TQQNADGQEDGESERNSNSSGDP--------GRQLTGAERA----STATAEETDIDAVEV 223
++ ++G + P G L E A ST +A T++D EV
Sbjct: 179 KEKRDKASQEGGDVLGARQDCTPSLKSLVATGNLLDLEETAKAPLSTVSANTTNMD--EV 236
Query: 224 PLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVSHPQ--EPMLTAS----PRMLLPSSSSK 277
P P L S V +LD E S ++PQ + LTA + L P K
Sbjct: 237 PRP--QALSGSSVVWELDDGLDEAFSRLAQSRTNPQVLDTGLTAQDMHYAQCLSPVDWDK 294
Query: 278 PPGLGTE 284
P GTE
Sbjct: 295 PDSSGTE 301
>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
sapiens]
Length = 304
Score = 70.5 bits (171), Expect = 3e-12
Identities = 70/274 (25%), Positives = 127/274 (46%), Gaps = 54/274 (19%)
Query: 20 LHNEDAF-QHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKK------KV 72
+H +A +H I + AK++GS +V +P + A+R++++ A++IKK KV
Sbjct: 14 MHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKF---ARHIKKSEGQKIPKV 70
Query: 73 SIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYI 132
+ +S+ GVK++ K K++ ++RI + + D D +IF++I
Sbjct: 71 ELQISIYGVKILEPKTKEVQ----------------HNCQLHRISFCADDKTDKRIFTFI 114
Query: 133 ARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNS 192
+D SN C VF S+K ++ I T+GQAF++ ++ L+ G +D E+
Sbjct: 115 CKDSESNKHLCYVFDSEKCAE--EITLTIGQAFDLAYRKFLE------SGGKDVETR--- 163
Query: 193 NSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTG 252
+Q+ G ++ ++ + + +E+ D LE +T + A GS T
Sbjct: 164 -------KQIAGLQK----RIQDLETENMELKNKVQD-LENQLRITQVSA--PPAGSMTP 209
Query: 253 SKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETP 286
S M+ SP + SS P GT+ P
Sbjct: 210 KSPSTDIFDMIPFSP---ISHQSSMPTRNGTQPP 240
>gi|140161500 ankyrin repeat and sterile alpha motif domain containing
1 [Homo sapiens]
Length = 1134
Score = 57.4 bits (137), Expect = 3e-08
Identities = 50/192 (26%), Positives = 82/192 (42%), Gaps = 25/192 (13%)
Query: 32 FEAKYVGSL---DVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKK 88
+EA Y+GS+ D+ S + A MR+ K K + + ++ GVK I
Sbjct: 942 YEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMK----KIPTIILSITYKGVKFIDASN 997
Query: 89 KKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKS 148
K + + + I I + D +DL F+YI +D ++ C+VF +
Sbjct: 998 KNV----------------IAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFST 1041
Query: 149 KKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERA 208
+ I+ T+GQAFEV ++L+LQ + A G E +S P ++ R
Sbjct: 1042 VDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRV--GVRK 1099
Query: 209 STATAEETDIDA 220
S + D DA
Sbjct: 1100 SALEPPDMDQDA 1111
>gi|50511947 cajalin 2 isoform b [Homo sapiens]
Length = 510
Score = 56.6 bits (135), Expect = 5e-08
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 19/157 (12%)
Query: 21 HNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVS---IMVS 77
H E ++A Y+GS+ + A ++R + + KKV + VS
Sbjct: 301 HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS 360
Query: 78 VDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGA 137
GVK I K + + + I I + D +DL F+YI +D
Sbjct: 361 YKGVKFIDATNKNI----------------IAEHEIRNISCAAQDPEDLSTFAYITKDLK 404
Query: 138 SNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQ 174
SN C+VF + + A I+ T+GQAFEV ++L+LQ
Sbjct: 405 SNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 441
>gi|50511945 cajalin 2 isoform a [Homo sapiens]
Length = 1248
Score = 56.6 bits (135), Expect = 5e-08
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 19/157 (12%)
Query: 21 HNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVS---IMVS 77
H E ++A Y+GS+ + A ++R + + KKV + VS
Sbjct: 1051 HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS 1110
Query: 78 VDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGA 137
GVK I K + + + I I + D +DL F+YI +D
Sbjct: 1111 YKGVKFIDATNKNI----------------IAEHEIRNISCAAQDPEDLSTFAYITKDLK 1154
Query: 138 SNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQ 174
SN C+VF + + A I+ T+GQAFEV ++L+LQ
Sbjct: 1155 SNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 1191
>gi|10047134 cajalin 2 isoform c [Homo sapiens]
Length = 414
Score = 56.6 bits (135), Expect = 5e-08
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 19/157 (12%)
Query: 21 HNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVS---IMVS 77
H E ++A Y+GS+ + A ++R + + KKV + VS
Sbjct: 217 HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS 276
Query: 78 VDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGA 137
GVK I K + + + I I + D +DL F+YI +D
Sbjct: 277 YKGVKFIDATNKNI----------------IAEHEIRNISCAAQDPEDLSTFAYITKDLK 320
Query: 138 SNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQ 174
SN C+VF + + A I+ T+GQAFEV ++L+LQ
Sbjct: 321 SNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 357
>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
Length = 609
Score = 54.3 bits (129), Expect = 3e-07
Identities = 44/148 (29%), Positives = 68/148 (45%), Gaps = 22/148 (14%)
Query: 22 NEDAFQHGIC-FEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDG 80
+EDA + G C F +Y+G ++V A++++ KA K K + VS DG
Sbjct: 69 DEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKL----KAMGRKSVKSVLWVSADG 124
Query: 81 VKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNI 140
++V+ K K LL+ Q E ++ + + D K FSYI RDG +
Sbjct: 125 LRVVDDKTKDLLVDQTIE----------------KVSFCAPDRNLDKAFSYICRDGTTRR 168
Query: 141 FRCNVFKSKKKSQAMRIVRTVGQAFEVC 168
+ C+ F + K S R+ VG AF C
Sbjct: 169 WICHCFLALKDS-GERLSHAVGCAFAAC 195
>gi|54144629 numb homolog isoform 4 [Homo sapiens]
Length = 592
Score = 51.2 bits (121), Expect = 2e-06
Identities = 63/262 (24%), Positives = 109/262 (41%), Gaps = 43/262 (16%)
Query: 22 NEDAFQHGIC-FEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDG 80
+E+ + G C F KY+G ++V A++R+ KA K K + VS DG
Sbjct: 28 DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRL----KATGKKAVKAVLWVSADG 83
Query: 81 VKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNI 140
++V+ +K K L++ Q E ++ + + D + FSYI RDG +
Sbjct: 84 LRVVDEKTKDLIVDQTIE----------------KVSFCAPDRNFDRAFSYICRDGTTRR 127
Query: 141 FRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGR 200
+ C+ F + K + R+ VG AF C L+ Q+ E E ++ D R
Sbjct: 128 WICHCFMAVKDT-GERLSHAVGCAFAAC----LERKQKR-------EKECGVTATFDASR 175
Query: 201 QL---TGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKE-GGSHTGSKVS 256
G+ R +TAT E+ + + + + + + TD VG +T S
Sbjct: 176 TTFTREGSFRVTTAT-EQAEREEIM-----KQMQDAKKAETDKIVVGSSVAPGNTAPSPS 229
Query: 257 HPQEPMLTASPRMLLPSSSSKP 278
P P A+ + + + + P
Sbjct: 230 SPTSPTSDATTSLEMNNPHAIP 251
>gi|20070356 numb homolog isoform 3 [Homo sapiens]
Length = 640
Score = 51.2 bits (121), Expect = 2e-06
Identities = 63/262 (24%), Positives = 109/262 (41%), Gaps = 43/262 (16%)
Query: 22 NEDAFQHGIC-FEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDG 80
+E+ + G C F KY+G ++V A++R+ KA K K + VS DG
Sbjct: 28 DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRL----KATGKKAVKAVLWVSADG 83
Query: 81 VKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNI 140
++V+ +K K L++ Q E ++ + + D + FSYI RDG +
Sbjct: 84 LRVVDEKTKDLIVDQTIE----------------KVSFCAPDRNFDRAFSYICRDGTTRR 127
Query: 141 FRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGR 200
+ C+ F + K + R+ VG AF C L+ Q+ E E ++ D R
Sbjct: 128 WICHCFMAVKDT-GERLSHAVGCAFAAC----LERKQKR-------EKECGVTATFDASR 175
Query: 201 QL---TGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKE-GGSHTGSKVS 256
G+ R +TAT E+ + + + + + + TD VG +T S
Sbjct: 176 TTFTREGSFRVTTAT-EQAEREEIM-----KQMQDAKKAETDKIVVGSSVAPGNTAPSPS 229
Query: 257 HPQEPMLTASPRMLLPSSSSKP 278
P P A+ + + + + P
Sbjct: 230 SPTSPTSDATTSLEMNNPHAIP 251
>gi|54144627 numb homolog isoform 2 [Homo sapiens]
Length = 603
Score = 50.1 bits (118), Expect = 5e-06
Identities = 65/269 (24%), Positives = 112/269 (41%), Gaps = 46/269 (17%)
Query: 22 NEDAFQHGIC-FEAKYVGSLDVPRPNSRVEIVAAMRRIRYE------FKAKNIKKK-KVS 73
+E+ + G C F KY+G ++V A++R++ E F K KK K
Sbjct: 28 DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAV 87
Query: 74 IMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIA 133
+ VS DG++V+ +K K L++ Q E ++ + + D + FSYI
Sbjct: 88 LWVSADGLRVVDEKTKDLIVDQTIE----------------KVSFCAPDRNFDRAFSYIC 131
Query: 134 RDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSN 193
RDG + + C+ F + K + R+ VG AF C L+ Q+ E E
Sbjct: 132 RDGTTRRWICHCFMAVKDT-GERLSHAVGCAFAAC----LERKQKR-------EKECGVT 179
Query: 194 SSGDPGRQL---TGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKE-GGS 249
++ D R G+ R +TAT E+ + + + + + + TD VG
Sbjct: 180 ATFDASRTTFTREGSFRVTTAT-EQAEREEIM-----KQMQDAKKAETDKIVVGSSVAPG 233
Query: 250 HTGSKVSHPQEPMLTASPRMLLPSSSSKP 278
+T S P P A+ + + + + P
Sbjct: 234 NTAPSPSSPTSPTSDATTSLEMNNPHAIP 262
>gi|54144625 numb homolog isoform 1 [Homo sapiens]
Length = 651
Score = 50.1 bits (118), Expect = 5e-06
Identities = 65/269 (24%), Positives = 112/269 (41%), Gaps = 46/269 (17%)
Query: 22 NEDAFQHGIC-FEAKYVGSLDVPRPNSRVEIVAAMRRIRYE------FKAKNIKKK-KVS 73
+E+ + G C F KY+G ++V A++R++ E F K KK K
Sbjct: 28 DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAV 87
Query: 74 IMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIA 133
+ VS DG++V+ +K K L++ Q E ++ + + D + FSYI
Sbjct: 88 LWVSADGLRVVDEKTKDLIVDQTIE----------------KVSFCAPDRNFDRAFSYIC 131
Query: 134 RDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSN 193
RDG + + C+ F + K + R+ VG AF C L+ Q+ E E
Sbjct: 132 RDGTTRRWICHCFMAVKDT-GERLSHAVGCAFAAC----LERKQKR-------EKECGVT 179
Query: 194 SSGDPGRQL---TGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKE-GGS 249
++ D R G+ R +TAT E+ + + + + + + TD VG
Sbjct: 180 ATFDASRTTFTREGSFRVTTAT-EQAEREEIM-----KQMQDAKKAETDKIVVGSSVAPG 233
Query: 250 HTGSKVSHPQEPMLTASPRMLLPSSSSKP 278
+T S P P A+ + + + + P
Sbjct: 234 NTAPSPSSPTSPTSDATTSLEMNNPHAIP 262
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 43.9 bits (102), Expect = 3e-04
Identities = 56/223 (25%), Positives = 84/223 (37%), Gaps = 39/223 (17%)
Query: 182 GQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPL------------PGND 229
G E E E + P R A ++ AEET E+ L P ++
Sbjct: 48 GSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHE 107
Query: 230 VLEFSRGVTDLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLST 289
L+ + +L ++ G S++ QE + + L P L
Sbjct: 108 QLQQPQPHLELQQQPQQDGQQQLSQLQ--QEKHQSVHHQELKPE-------------LQL 152
Query: 290 HHQMQLLQ-------QLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQN 342
HQ Q LQ Q LQQQQ+Q Q AQ +Q + +L+ Q + QLL Q
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ-----EQQVLQQQEQLQQQVQEQQLLQQQ 207
Query: 343 KDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGAL 385
++ LQ LL +Q Q + + Q Q L + + G L
Sbjct: 208 QEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQL 250
Score = 36.6 bits (83), Expect = 0.055
Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 9/96 (9%)
Query: 287 LSTHHQMQLLQQLLQQQQQ--QTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKD 344
L Q QL QQLLQQQQ Q Q+ Q L+ QL + +L+ Q + QLL Q ++
Sbjct: 242 LLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQ-QQLLQQQQE 300
Query: 345 MLQHISLL-----VKQVQELELKLSGQNAMGSQDSL 375
LQ L ++ +E+EL+L + +GS+ L
Sbjct: 301 QLQQQQLQPPPLEPEEEEEVELELMPVD-LGSEQEL 335
Score = 36.2 bits (82), Expect = 0.072
Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 292 QMQLLQQLLQQQQQQTQVAVAQVH------LLKDQLAAEAAARLEAQARVHQLLLQNKDM 345
Q QLLQQ Q QQQQ Q Q+ LL+ Q + + QA++ Q LL+ +
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQA 272
Query: 346 LQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLG 405
LL++Q ++L+ + Q Q+ L + + P +P + +L P+
Sbjct: 273 QLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQ----PPPLEPEEEEEVELELMPVD 328
Query: 406 AG 407
G
Sbjct: 329 LG 330
Score = 35.4 bits (80), Expect = 0.12
Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 292 QMQLLQQLLQQQ---QQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQ--LLLQNKDML 346
Q QL QQ+ +QQ QQQ Q+ Q+ ++QL + + + Q + Q LLLQ + L
Sbjct: 191 QEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQL 250
Query: 347 QHISLLVKQVQELELKLSGQNAMGSQDSLLE 377
Q L +Q Q + L Q A Q LL+
Sbjct: 251 QQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQ 281
Score = 33.1 bits (74), Expect = 0.61
Identities = 29/77 (37%), Positives = 40/77 (51%), Gaps = 11/77 (14%)
Query: 287 LSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDML 346
L Q+ LLQQ Q QQQ Q AQ L+ QL + A+L+ QLLLQ ++ L
Sbjct: 235 LQQQQQLLLLQQQGQLQQQLLQQQQAQ---LQQQLLEQQQAQLQ-----QQLLLQQQEQL 286
Query: 347 ---QHISLLVKQVQELE 360
Q LL +Q ++L+
Sbjct: 287 QQQQQQQLLQQQQEQLQ 303
Score = 30.4 bits (67), Expect = 4.0
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 11/110 (10%)
Query: 281 LGTETPLSTHHQMQLLQQLLQQQQQQ---------TQVAVAQVHLLKDQLAAEAAARLEA 331
L + L Q QLLQQ +Q QQQ + ++ L+ L +E +
Sbjct: 280 LQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQR 339
Query: 332 QARVHQLLLQNKDMLQHISL-LVKQVQELELKL-SGQNAMGSQDSLLEIT 379
Q Q L+ + + + L L +++Q+LE +L Q + Q+ LE+T
Sbjct: 340 QELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELT 389
Score = 29.3 bits (64), Expect = 8.8
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 11/89 (12%)
Query: 278 PPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQ 337
P LG+E L Q QQ L++QQ+Q Q+ LK Q E +LE Q Q
Sbjct: 326 PVDLGSEQELEQQRQELERQQELERQQEQRQLQ------LKLQ---EELQQLEQQLEQQQ 376
Query: 338 LLLQNKDMLQHIS--LLVKQVQELELKLS 364
L+ +++ ++ L Q QE++L+L+
Sbjct: 377 QQLEQQEVQLELTPVELGAQQQEVQLELT 405
>gi|169211037 PREDICTED: similar to mitogen-activated protein kinase
8 interacting protein 1 [Homo sapiens]
Length = 423
Score = 43.1 bits (100), Expect = 6e-04
Identities = 39/151 (25%), Positives = 69/151 (45%), Gaps = 21/151 (13%)
Query: 32 FEAKYVGSLDVPRPNSRVEIVAAM------RRIRYEFKAKNIKKKKVSIMVSVDGVKVIL 85
F K++GS+ VP V + AAM RR+ F + + +SV GVK+ +
Sbjct: 279 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPS----SCVLEISVRGVKIGI 334
Query: 86 KKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNV 145
K K + + K I + + ++ K F +I + A + F C+V
Sbjct: 335 KADDSQEAKGNKCSHFFQLK---------NISFRGYHPKNNKYFGFITKHLADHRFACHV 385
Query: 146 FKSKKKSQAMRIVRTVGQAFEVCHKLSLQHT 176
F S+ ++A + +VG+AF+ HK +++T
Sbjct: 386 FVSEDSTKA--LAESVGRAFQQFHKQFVEYT 414
>gi|239740950 PREDICTED: similar to mitogen-activated protein kinase
8 interacting protein 1 [Homo sapiens]
Length = 442
Score = 43.1 bits (100), Expect = 6e-04
Identities = 40/156 (25%), Positives = 70/156 (44%), Gaps = 21/156 (13%)
Query: 32 FEAKYVGSLDVPRPNSRVEIVAAM------RRIRYEFKAKNIKKKKVSIMVSVDGVKVIL 85
F K++GS+ VP V + AAM RR+ F + + +SV GVK+ +
Sbjct: 298 FRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPS----SCVLEISVRGVKIGV 353
Query: 86 KKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNV 145
K K + + K I + + ++ K F +I + A + F C+V
Sbjct: 354 KADDSQEAKGNKCSHFFQLK---------NISFRGYHPKNNKYFGFITKHLADHRFACHV 404
Query: 146 FKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNAD 181
F S+ ++A + +VG+AF+ HK +++T D
Sbjct: 405 FVSEDSTKA--LAESVGRAFQQFHKQFVEYTCPTED 438
>gi|4885433 mitogen-activated protein kinase 8 interacting protein 1
[Homo sapiens]
Length = 711
Score = 40.8 bits (94), Expect = 0.003
Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 21/156 (13%)
Query: 32 FEAKYVGSLDVPRPNSRVEIVAAM------RRIRYEFKAKNIKKKKVSIMVSVDGVKVIL 85
F K++GS+ VP + AAM RR+ F + + +SV GVK+ +
Sbjct: 567 FRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPS----SCVLEISVRGVKIGV 622
Query: 86 KKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNV 145
K K + + K I + + ++ K F +I + A + F C+V
Sbjct: 623 KADDSQEAKGNKCSHFFQLK---------NISFCGYHPKNNKYFGFITKHPADHRFACHV 673
Query: 146 FKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNAD 181
F S+ ++A + +VG+AF+ +K +++T D
Sbjct: 674 FVSEDSTKA--LAESVGRAFQQFYKQFVEYTCPTED 707
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 38.1 bits (87), Expect = 0.019
Identities = 58/258 (22%), Positives = 99/258 (38%), Gaps = 33/258 (12%)
Query: 248 GSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQT 307
G+ G+ ++ P EP A+ + L +S+ Q Q QQ QQQQQQ
Sbjct: 1694 GNPIGANIASPSEPK-EANRKKLADMIASR--------------QQQQQQQQQQQQQQQQ 1738
Query: 308 QVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHIS------LLVKQVQELEL 361
Q + + Q+ A L+ QA + Q L N +L H L ++Q Q L
Sbjct: 1739 QQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLF 1798
Query: 362 KLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGR 421
+A + + + SGAL + T P L + +H P +
Sbjct: 1799 PFYIPSAEFQLNPEVSLPVTSGALTL----TGTGPGLLEDLKAQVQVPQQSHQQILPQQQ 1854
Query: 422 RDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQ 481
++ L + L P + + ++ +E S+ E ++ E E ++ +
Sbjct: 1855 QNQLSIAQSHSALLQPSQHPEKKNKLVI--------KEKEKESQRERDSAEGGEGNTGPK 1906
Query: 482 EELPRLLNVLQRQELGDG 499
E LP L +++EL G
Sbjct: 1907 ETLPDALKAKEKKELAPG 1924
>gi|66934969 runt-related transcription factor 2 isoform c [Homo
sapiens]
Length = 507
Score = 37.7 bits (86), Expect = 0.025
Identities = 29/78 (37%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 258 PQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLL 317
P +P + S R PSSS +P + +P+ Q Q QQ QQQQQQ Q Q
Sbjct: 4 PVDP--STSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAA 61
Query: 318 KDQLAAEAAARLEAQARV 335
AA AAA A R+
Sbjct: 62 AAAAAAAAAAAAAAVPRL 79
>gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]
Length = 1069
Score = 37.7 bits (86), Expect = 0.025
Identities = 38/123 (30%), Positives = 53/123 (43%), Gaps = 13/123 (10%)
Query: 275 SSKPPGLGTETPLSTHHQMQLLQQLL------QQQQQQTQVAVAQVHLLKDQLAAEAAAR 328
S P GL +PL ++++ ++ +Q QQ+ + Q + K L AE +
Sbjct: 12 SEVPVGLEPISPLDLRTDLRMMMPVVDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQ 71
Query: 329 LEAQARVHQLLLQNKDMLQHISLLVKQVQEL---ELKLSGQNAMGSQDSLLEITFRSGAL 385
E R HQ LQ LQ L +KQ QEL E KL Q Q+ +E R L
Sbjct: 72 HENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQR----QEQEVERHRREQQL 127
Query: 386 PVL 388
P L
Sbjct: 128 PPL 130
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 37.7 bits (86), Expect = 0.025
Identities = 71/296 (23%), Positives = 111/296 (37%), Gaps = 52/296 (17%)
Query: 128 IFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGE 187
I + +A DG + C + +KK E CH+ A + G+
Sbjct: 7 ISAQLALDGVGTMVNCTIKSEEKK--------------EPCHEAP--QGSATAAEPQPGD 50
Query: 188 SERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEG 247
R S S DP G R S + + E PG V E + G + K
Sbjct: 51 PARASQDSADPQAPAQGNFRGSWDCSSPEGNGSPEPKRPG--VSEAASGSQE-----KLD 103
Query: 248 GSHTGSKVSHPQEPMLTAS--PRMLLPSSSSKPPGLGTETPLSTH--------HQMQLLQ 297
+ +V E +L++ R L +S GT+ L+ HQ+ L+
Sbjct: 104 FNRNLKEVVPAIEKLLSSDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLR 163
Query: 298 -QLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQ-ARVHQLLLQNKDMLQHISLLVKQ 355
QLL +Q +A K Q E A + + Q A+ Q L+Q + I+LL +Q
Sbjct: 164 DQLLTAHSEQKNMAAMLFE--KQQQQMELARQQQEQIAKQQQQLIQQQ---HKINLLQQQ 218
Query: 356 VQELELKL--------SGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPP 403
+Q++ + S Q + DS L + + P+ C P + LHSPP
Sbjct: 219 IQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQ----PIPCKPVEYPLQLLHSPP 270
>gi|226442791 runt-related transcription factor 2 isoform b [Homo
sapiens]
Length = 499
Score = 37.4 bits (85), Expect = 0.032
Identities = 27/72 (37%), Positives = 33/72 (45%)
Query: 264 TASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAA 323
+ S R PSSS +P + +P+ Q Q QQ QQQQQQ Q Q AA
Sbjct: 22 STSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAA 81
Query: 324 EAAARLEAQARV 335
AAA A R+
Sbjct: 82 AAAAAAAAVPRL 93
>gi|226442783 runt-related transcription factor 2 isoform a [Homo
sapiens]
Length = 521
Score = 37.4 bits (85), Expect = 0.032
Identities = 27/72 (37%), Positives = 33/72 (45%)
Query: 264 TASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAA 323
+ S R PSSS +P + +P+ Q Q QQ QQQQQQ Q Q AA
Sbjct: 22 STSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAA 81
Query: 324 EAAARLEAQARV 335
AAA A R+
Sbjct: 82 AAAAAAAAVPRL 93
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 37.4 bits (85), Expect = 0.032
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Query: 261 PMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQ 320
P++++ ++ S+ S +T HQMQL QQ QQQQQQ + Q L + Q
Sbjct: 409 PLISSMGTTMVGSAPSTQVSPSVQTQ---QHQMQLQQQ--QQQQQQQMQQMQQQQLQQHQ 463
Query: 321 LAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKL 363
+ + +++ Q H + + QH+ + Q Q+L+ +L
Sbjct: 464 MHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQ-QQLQQQL 505
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 37.4 bits (85), Expect = 0.032
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Query: 261 PMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQ 320
P++++ ++ S+ S +T HQMQL QQ QQQQQQ + Q L + Q
Sbjct: 414 PLISSMGTTMVGSAPSTQVSPSVQTQ---QHQMQLQQQ--QQQQQQQMQQMQQQQLQQHQ 468
Query: 321 LAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKL 363
+ + +++ Q H + + QH+ + Q Q+L+ +L
Sbjct: 469 MHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQ-QQLQQQL 510
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 37.4 bits (85), Expect = 0.032
Identities = 47/192 (24%), Positives = 66/192 (34%), Gaps = 32/192 (16%)
Query: 247 GGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPP---------------GLGTETPLSTHH 291
G S+ ++ +P A P LP + +K P GL + + H
Sbjct: 404 GSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQH 463
Query: 292 QMQLLQQLLQQ----------------QQQQTQVAVAQVHLLKDQLAAEAAARLEAQARV 335
Q QL + QQ QQQQ Q Q Q A A + +Q
Sbjct: 464 QQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGS 523
Query: 336 HQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLE-ITFRSGALPVLCDPTTP 394
Q L+QN Q +Q Q+L L Q M Q +L + T +G P P
Sbjct: 524 QQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAP 583
Query: 395 KPEDLHSPPLGA 406
+P P + A
Sbjct: 584 QPAPAQEPAIQA 595
>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
Length = 555
Score = 37.4 bits (85), Expect = 0.032
Identities = 41/168 (24%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 171 LSLQHTQQNADGQEDGES-----ERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPL 225
+S +HT+ DGES + SSG P G E S EE + A +
Sbjct: 3 VSSEHTKDPGGEGGDGESLAARPSKIKASSGPPTSPEPG-ELESEPEEEEEEQAASQGGT 61
Query: 226 PGNDVLEFSRGVTDLDAVGKEGGSHTGSKVS---HPQEPMLTASPRMLLPSSSSKPPGLG 282
++ E +G+T +A G+EG G P+EP + P PG G
Sbjct: 62 AADEQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPE-----PGAG 116
Query: 283 TETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLE 330
E L + L+Q + ++ + Q ++ + +++ AA A E
Sbjct: 117 PE-ELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETE 163
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 37.0 bits (84), Expect = 0.042
Identities = 39/132 (29%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 245 KEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQ 304
++ GS G +SH Q+ +++ S + P S++P G L Q Q LQQ Q QQ
Sbjct: 3865 QQQGSMAG--LSHLQQSLMSHSGQ---PKLSAQPMG-----SLQQLQQQQQLQQQQQLQQ 3914
Query: 305 QQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLS 364
QQ Q Q L + Q L+ Q + QL Q + LQ ++Q Q+ + +
Sbjct: 3915 QQQQQLQQQQQLQQQQ--------LQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQF 3966
Query: 365 GQNAMGSQDSLL 376
Q Q LL
Sbjct: 3967 QQQQQQQQMGLL 3978
Score = 31.6 bits (70), Expect = 1.8
Identities = 44/149 (29%), Positives = 59/149 (39%), Gaps = 29/149 (19%)
Query: 244 GKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPG------LGTETPLSTHHQMQLLQ 297
G+ GG + ++ Q+ + L S PG LG ++ L Q+QL Q
Sbjct: 3666 GQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQ 3725
Query: 298 Q-------LLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDML---- 346
Q L QQQQQQ Q Q HLL Q+A + + + +Q L L
Sbjct: 3726 QRMQLAQKLQQQQQQQQQ----QQHLL-GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780
Query: 347 QHISLLVKQVQELELKLSGQNAMGSQDSL 375
H LLV+Q LS Q G Q L
Sbjct: 3781 SHQGLLVQQ-------LSPQPPQGPQGML 3802
Score = 31.6 bits (70), Expect = 1.8
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 291 HQMQLLQQLLQQQQQQTQVAVAQV-HLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHI 349
H++ QQ QQQQ Q Q ++A + HL + ++ +L AQ LQ + LQ
Sbjct: 3850 HRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQ 3909
Query: 350 SLLVKQVQE 358
L +Q Q+
Sbjct: 3910 QQLQQQQQQ 3918
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 36.2 bits (82), Expect = 0.072
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 273 SSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQ 332
+S P + + + Q+QL Q LQQQQQQ Q Q L+ Q + Q
Sbjct: 133 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ---------QQQ 183
Query: 333 ARVHQLLLQNKDMLQHISLLVKQVQELE 360
+ Q Q M Q +V+Q Q+L+
Sbjct: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQ 211
Score = 32.3 bits (72), Expect = 1.0
Identities = 68/313 (21%), Positives = 109/313 (34%), Gaps = 57/313 (18%)
Query: 136 GASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQE----------- 184
G +R F+ K SQ +R G A K H A ++
Sbjct: 5 GQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLII 64
Query: 185 ---DGESERNSNSSGDPG---RQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT 238
D ++++ S DP + LTG A A + +P + G+
Sbjct: 65 HFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAG----------IGMPPRGPGQSLGGMG 114
Query: 239 DLDAVGK------EGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQ 292
L A+G+ + T H + TA+P+ L + L Q
Sbjct: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQ---------QVALQQQQQ 165
Query: 293 MQLLQQ----LLQQQQQQTQVA--VAQVHLLKDQLAA--EAAARLEAQARVHQLLL---- 340
Q QQ LQQQQQQ Q AQ ++ Q A + +L+ Q + Q L+
Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225
Query: 341 QNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLH 400
QN+ +Q ++++ +L+L+ Q Q + A P + P +P+
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL---QAQPPIQQPPMQQPQPPP 282
Query: 401 SPPLGAGLADFAH 413
S L L H
Sbjct: 283 SQALPQQLQQMHH 295
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 36.2 bits (82), Expect = 0.072
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 273 SSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQ 332
+S P + + + Q+QL Q LQQQQQQ Q Q L+ Q + Q
Sbjct: 133 TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQ---------QQQ 183
Query: 333 ARVHQLLLQNKDMLQHISLLVKQVQELE 360
+ Q Q M Q +V+Q Q+L+
Sbjct: 184 QQQQQFQAQQSAMQQQFQAVVQQQQQLQ 211
Score = 32.3 bits (72), Expect = 1.0
Identities = 68/313 (21%), Positives = 109/313 (34%), Gaps = 57/313 (18%)
Query: 136 GASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQE----------- 184
G +R F+ K SQ +R G A K H A ++
Sbjct: 5 GQETDWRSTAFRQKLVSQIEDAMRKAGVAHSKSSKDMESHVFLKAKTRDEYLSLVARLII 64
Query: 185 ---DGESERNSNSSGDPG---RQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVT 238
D ++++ S DP + LTG A A + +P + G+
Sbjct: 65 HFRDIHNKKSQASVSDPMNALQSLTGGPAAGAAG----------IGMPPRGPGQSLGGMG 114
Query: 239 DLDAVGK------EGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQ 292
L A+G+ + T H + TA+P+ L + L Q
Sbjct: 115 SLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQ---------QVALQQQQQ 165
Query: 293 MQLLQQ----LLQQQQQQTQVA--VAQVHLLKDQLAA--EAAARLEAQARVHQLLL---- 340
Q QQ LQQQQQQ Q AQ ++ Q A + +L+ Q + Q L+
Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225
Query: 341 QNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLH 400
QN+ +Q ++++ +L+L+ Q Q + A P + P +P+
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL---QAQPPIQQPPMQQPQPPP 282
Query: 401 SPPLGAGLADFAH 413
S L L H
Sbjct: 283 SQALPQQLQQMHH 295
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,491,426
Number of Sequences: 37866
Number of extensions: 1033912
Number of successful extensions: 5110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 133
Number of HSP's that attempted gapping in prelim test: 4343
Number of HSP's gapped (non-prelim): 514
length of query: 506
length of database: 18,247,518
effective HSP length: 107
effective length of query: 399
effective length of database: 14,195,856
effective search space: 5664146544
effective search space used: 5664146544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.