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Search of human proteins with 31317270
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31317270 WD repeat and FYVE domain containing 3 isoform 3
[Homo sapiens]
(281 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 593 e-170
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 593 e-170
gi|217272865 myotubularin related protein 4 [Homo sapiens] 73 2e-13
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 70 2e-12
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 68 1e-11
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 68 1e-11
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 68 1e-11
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 68 1e-11
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 67 2e-11
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 67 2e-11
gi|153791377 apoptosis-inducing protein D [Homo sapiens] 66 3e-11
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 65 5e-11
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 65 9e-11
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 65 9e-11
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 64 1e-10
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 62 6e-10
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 62 6e-10
gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens] 60 2e-09
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 59 4e-09
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 59 6e-09
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 58 8e-09
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 57 1e-08
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 57 1e-08
gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Hom... 57 1e-08
gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Hom... 57 1e-08
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 57 2e-08
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 56 3e-08
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 56 3e-08
gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens] 56 4e-08
gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 56 4e-08
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 593 bits (1529), Expect = e-170
Identities = 281/281 (100%), Positives = 281/281 (100%)
Query: 1 MEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPS 60
MEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPS
Sbjct: 1 MEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPS 60
Query: 61 STSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLS 120
STSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLS
Sbjct: 61 STSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLS 120
Query: 121 HPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRI 180
HPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRI
Sbjct: 121 HPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRI 180
Query: 181 LVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQ 240
LVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQ
Sbjct: 181 LVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQ 240
Query: 241 KCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC 281
KCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC
Sbjct: 241 KCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC 281
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 593 bits (1529), Expect = e-170
Identities = 281/281 (100%), Positives = 281/281 (100%)
Query: 1 MEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPS 60
MEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPS
Sbjct: 3246 MEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPS 3305
Query: 61 STSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLS 120
STSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLS
Sbjct: 3306 STSHRPRAASCRATAAWCTDSGSDDSRRWSDQLSLDEKDGFIFVNYSEGQTRAHLQGPLS 3365
Query: 121 HPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRI 180
HPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRI
Sbjct: 3366 HPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRI 3425
Query: 181 LVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQ 240
LVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQ
Sbjct: 3426 LVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQ 3485
Query: 241 KCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC 281
KCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC
Sbjct: 3486 KCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRNC 3526
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 73.2 bits (178), Expect = 2e-13
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 24/172 (13%)
Query: 122 PHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFD-RKDNAHPAE--------VTALG 172
P P + +++ GY+ E + + R + D R A PAE T L
Sbjct: 1015 PFPTDVIQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLK 1074
Query: 173 IS---------KDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFS 223
S DHS + ++ SW D+ + WV D C C F
Sbjct: 1075 ESDGSDTEDFGSDHSEDCLSEA-----SWEPVDKK-ETEVTRWVPDHMASHCYNCDCEFW 1128
Query: 224 LTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSE 275
L +RRHHCRNCG +FC C + I ++ PV VC +CY ++Q R E
Sbjct: 1129 LAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARE 1180
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 70.1 bits (170), Expect = 2e-12
Identities = 26/60 (43%), Positives = 37/60 (61%)
Query: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
WV DE C+ C F++ R+HHCR+CG++FC +CS + + R PVRVC +CY
Sbjct: 814 WVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 67.8 bits (164), Expect = 1e-11
Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 17/160 (10%)
Query: 107 SEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPA 166
SE + R LQ L H +R + G + E + + K + + ++ A
Sbjct: 445 SEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQA--- 501
Query: 167 EVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADH-WVKDEGGDSCSGCSVRFSLT 225
+ +G+ S++ + D + + ++ H W+KD+ C C FS++
Sbjct: 502 -LQEMGLHLSQSKLKMEDIK----------EVNQALKGHAWLKDDEATHCRQCEKEFSIS 550
Query: 226 ERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
R+HHCRNCG +FC CS +E+ PVRVC +C+
Sbjct: 551 RRKHHCRNCGHIFCNTCS--SNELALPSYPKPVRVCDSCH 588
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 67.8 bits (164), Expect = 1e-11
Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 17/160 (10%)
Query: 107 SEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPA 166
SE + R LQ L H +R + G + E + + K + + ++ A
Sbjct: 445 SEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQA--- 501
Query: 167 EVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADH-WVKDEGGDSCSGCSVRFSLT 225
+ +G+ S++ + D + + ++ H W+KD+ C C FS++
Sbjct: 502 -LQEMGLHLSQSKLKMEDIK----------EVNQALKGHAWLKDDEATHCRQCEKEFSIS 550
Query: 226 ERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
R+HHCRNCG +FC CS +E+ PVRVC +C+
Sbjct: 551 RRKHHCRNCGHIFCNTCS--SNELALPSYPKPVRVCDSCH 588
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 67.8 bits (164), Expect = 1e-11
Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 17/160 (10%)
Query: 107 SEGQTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPA 166
SE + R LQ L H +R + G + E + + K + + ++ A
Sbjct: 553 SEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQA--- 609
Query: 167 EVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADH-WVKDEGGDSCSGCSVRFSLT 225
+ +G+ S++ + D + + ++ H W+KD+ C C FS++
Sbjct: 610 -LQEMGLHLSQSKLKMEDIK----------EVNQALKGHAWLKDDEATHCRQCEKEFSIS 658
Query: 226 ERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
R+HHCRNCG +FC CS +E+ PVRVC +C+
Sbjct: 659 RRKHHCRNCGHIFCNTCS--SNELALPSYPKPVRVCDSCH 696
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 67.8 bits (164), Expect = 1e-11
Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 2/60 (3%)
Query: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
W+KD+ C C FSL++R+HHCRNCG++FC CS +E+ PVRVC +C+
Sbjct: 572 WLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACS--DNELPLPSSPKPVRVCDSCH 629
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 67.0 bits (162), Expect = 2e-11
Identities = 31/69 (44%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 203 ADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQ 262
A WV E C C V+F + R+HHCR CGQ+FC KCS S I + I VRVC+
Sbjct: 157 APDWVDAE---ECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCE 213
Query: 263 NCYYNLQHE 271
CY L +
Sbjct: 214 PCYEQLNRK 222
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 67.0 bits (162), Expect = 2e-11
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Query: 198 PGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSP 257
P S A W+ D C C+ F+LT RRHHCR CG++ CQ CS + + LK + P
Sbjct: 1211 PLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLK-NQP 1269
Query: 258 VRVCQNCYYNLQ 269
RVC++C+ LQ
Sbjct: 1270 ARVCEHCFQELQ 1281
>gi|153791377 apoptosis-inducing protein D [Homo sapiens]
Length = 279
Score = 66.2 bits (160), Expect = 3e-11
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 198 PGRSAADHWVKDEGGDSCSGCS-VRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISS 256
P A W+ D+ D C C+ RFS RRHHCR CG + C +CSR + + RL
Sbjct: 141 PSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLS-PK 199
Query: 257 PVRVCQNCYYNLQHERGSED 276
PVRVC CY L ++ E+
Sbjct: 200 PVRVCSLCYRELAAQQRQEE 219
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 65.5 bits (158), Expect = 5e-11
Identities = 25/54 (46%), Positives = 35/54 (64%)
Query: 212 GDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
G C C+ RF +T R+HHCR+CG+L C KCS + I + ++ PVRVC C+
Sbjct: 1108 GSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICF 1161
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 64.7 bits (156), Expect = 9e-11
Identities = 27/78 (34%), Positives = 37/78 (47%)
Query: 199 GRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPV 258
G W+ D C C F L R+HHCRNCG +FC C + + ++ P
Sbjct: 1072 GDEVMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPS 1131
Query: 259 RVCQNCYYNLQHERGSED 276
RVC++CY +L S D
Sbjct: 1132 RVCKSCYSSLHPTSSSID 1149
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 64.7 bits (156), Expect = 9e-11
Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 191 SWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIK 250
SW D+ W+ D C C F L R+HHCRNCG +FC C + +
Sbjct: 1102 SWEQVDKQDTEMT-RWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVP 1160
Query: 251 RLKISSPVRVCQNCYYNLQHERGSED 276
++ P RVC++CY +L S D
Sbjct: 1161 SQQLFEPSRVCKSCYSSLHPTSSSID 1186
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 63.9 bits (154), Expect = 1e-10
Identities = 28/64 (43%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
W +D +C C FS+T RRHHCR CG +FC +CS + K PVRVC C+
Sbjct: 1349 WAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSK--KPVRVCDACF 1406
Query: 266 YNLQ 269
+LQ
Sbjct: 1407 NDLQ 1410
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 62.0 bits (149), Expect = 6e-10
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Query: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
WV D +C C V+F+ T+RRHHCR CG++FC C + +++ L+ RVC CY
Sbjct: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE--KEARVCVVCY 801
Query: 266 YNLQHERGSE 275
+ + E
Sbjct: 802 ETISKAQAFE 811
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 62.0 bits (149), Expect = 6e-10
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Query: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
WV D +C C V+F+ T+RRHHCR CG++FC C + +++ L+ RVC CY
Sbjct: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE--KEARVCVVCY 801
Query: 266 YNLQHERGSE 275
+ + E
Sbjct: 802 ETISKAQAFE 811
>gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens]
Length = 655
Score = 60.1 bits (144), Expect = 2e-09
Identities = 28/64 (43%), Positives = 39/64 (60%), Gaps = 2/64 (3%)
Query: 203 ADHWVKDEGGDSCSGCSVRFS-LTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVC 261
A WV+D+ C C F+ LT RRHHCR CG + C +CS +++E+K + P RVC
Sbjct: 452 APQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCARCSDYRAELK-YDDNRPNRVC 510
Query: 262 QNCY 265
+CY
Sbjct: 511 LHCY 514
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 59.3 bits (142), Expect = 4e-09
Identities = 22/59 (37%), Positives = 31/59 (52%)
Query: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNC 264
WV D+ C C +F R+HHCR CG+ FC +C + ++R+ PVR C C
Sbjct: 41 WVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQCAEC 99
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 58.5 bits (140), Expect = 6e-09
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Query: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
WV D +C C RF+ T+RRHHCR CG++FC C + ++ + RVC C+
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVICH 754
Query: 266 YNLQHERGSED 276
L + + E+
Sbjct: 755 SVLMNAQAWEN 765
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 58.2 bits (139), Expect = 8e-09
Identities = 40/113 (35%), Positives = 51/113 (45%), Gaps = 11/113 (9%)
Query: 159 RKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQ----PGRSAADH-WVKDEGGD 213
R +A + GIS HS L R R F + Q P A H WV DE
Sbjct: 1761 RSPSAEFSPAAPPGISSIHSPSL----RERSFPPTQPSQEFVPPATPPARHQWVPDETES 1816
Query: 214 SCSGCS-VRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
C C F++ RRHHCR CG+L C CS + ++ + +P RVC CY
Sbjct: 1817 ICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCR-ENPARVCDQCY 1868
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 57.4 bits (137), Expect = 1e-08
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
WV D +C C RF+ T+RRHHCR CG++FC C + ++ + RVC C+
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVICH 754
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 57.4 bits (137), Expect = 1e-08
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
WV D +C C RF+ T+RRHHCR CG++FC C + ++ + RVC C+
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD-RKEARVCVICH 754
>gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Homo
sapiens]
Length = 362
Score = 57.4 bits (137), Expect = 1e-08
Identities = 25/60 (41%), Positives = 31/60 (51%)
Query: 205 HWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNC 264
+WV D C C FS+ +HHCR CGQ FC +CS + + PVRVC NC
Sbjct: 296 YWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 355
Score = 55.8 bits (133), Expect = 4e-08
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 9/110 (8%)
Query: 160 KDNAHPAEVTALGIS---KDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCS 216
KDN + A+ G++ + S + +G ++ V SW ++DQ A +W + SC+
Sbjct: 136 KDNNNAAQRLLDGMNFMAQSVSELSLGPTKA-VTSW-LTDQ---IAPAYWRPNSQILSCN 190
Query: 217 GCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEI-KRLKISSPVRVCQNCY 265
C+ F + +HHCR CG+ FC CS + +R +PVRVC NCY
Sbjct: 191 KCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCY 240
>gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Homo
sapiens]
Length = 777
Score = 57.4 bits (137), Expect = 1e-08
Identities = 25/60 (41%), Positives = 31/60 (51%)
Query: 205 HWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNC 264
+WV D C C FS+ +HHCR CGQ FC +CS + + PVRVC NC
Sbjct: 711 YWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNC 770
Score = 55.8 bits (133), Expect = 4e-08
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 9/110 (8%)
Query: 160 KDNAHPAEVTALGIS---KDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCS 216
KDN + A+ G++ + S + +G ++ V SW ++DQ A +W + SC+
Sbjct: 551 KDNNNAAQRLLDGMNFMAQSVSELSLGPTKA-VTSW-LTDQ---IAPAYWRPNSQILSCN 605
Query: 217 GCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEI-KRLKISSPVRVCQNCY 265
C+ F + +HHCR CG+ FC CS + +R +PVRVC NCY
Sbjct: 606 KCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCY 655
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 57.0 bits (136), Expect = 2e-08
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 199 GRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCR---------NCGQLFCQKCSRFQSEI 249
G W+ D C C F L R+HHCR NCG +FC C + +
Sbjct: 1072 GDEVMTRWLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCCNQKVPV 1131
Query: 250 KRLKISSPVRVCQNCYYNLQHERGSED 276
++ P RVC++CY +L S D
Sbjct: 1132 PSQQLFEPSRVCKSCYSSLHPTSSSID 1158
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 56.2 bits (134), Expect = 3e-08
Identities = 22/60 (36%), Positives = 32/60 (53%)
Query: 205 HWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNC 264
+W+ D C CS +F+ RRHHCR CGQ+FC +C + K + + +R C C
Sbjct: 154 YWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYC 213
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 56.2 bits (134), Expect = 3e-08
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 7/124 (5%)
Query: 158 DRKDNAHPAEVTALGISKDH-SRILVGDSRGRVFSWSVSD----QPGRSAADHWVKDEGG 212
+R D A++ L +K + L+ R + W SD Q SA + W+ D
Sbjct: 1117 ERNDQKMLADLDDLNRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEERWLGDTEA 1176
Query: 213 DSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHER 272
+ C C FS RRHHCR CG++FC C + + R C+ C+ L
Sbjct: 1177 NHCLDCKREFSWMVRRHHCRICGRIFCYYCC--NNYVLSKHGGKKERCCRACFQKLSEGP 1234
Query: 273 GSED 276
GS D
Sbjct: 1235 GSPD 1238
>gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens]
Length = 766
Score = 55.8 bits (133), Expect = 4e-08
Identities = 29/80 (36%), Positives = 45/80 (56%), Gaps = 6/80 (7%)
Query: 203 ADHWVKDEGGDSCSGCSVRFS-LTERRHHCRNCGQLFCQKCSRFQSEIK--RLKISSPVR 259
A W++D C C F+ LT RRHHCR CG + C KCS ++++++ K+S +
Sbjct: 553 APRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLS---K 609
Query: 260 VCQNCYYNLQHERGSEDGPR 279
VC++CY + SE+ R
Sbjct: 610 VCKDCYQIISGFTDSEEKKR 629
>gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 55.8 bits (133), Expect = 4e-08
Identities = 25/59 (42%), Positives = 36/59 (61%), Gaps = 6/59 (10%)
Query: 208 KDEGGDSCSGCSVRF-SLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
+D+ SC C F S+T+RRHHC+ CG + C KCS F++E R RVC++C+
Sbjct: 531 RDKEKQSCKSCGETFNSITKRRHHCKLCGAVICGKCSEFKAENSRQS-----RVCRDCF 584
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,150,607
Number of Sequences: 37866
Number of extensions: 629190
Number of successful extensions: 5739
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 99
Number of HSP's successfully gapped in prelim test: 165
Number of HSP's that attempted gapping in prelim test: 5283
Number of HSP's gapped (non-prelim): 556
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.