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Search of human proteins with 30794488
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30794488 kinesin family member 27 [Homo sapiens]
(1401 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30794488 kinesin family member 27 [Homo sapiens] 2737 0.0
gi|203096856 kinesin family member 7 [Homo sapiens] 915 0.0
gi|116686122 kinesin family member 4 [Homo sapiens] 372 e-102
gi|38569484 kinesin family member 21A [Homo sapiens] 368 e-101
gi|150010604 kinesin family member 4B [Homo sapiens] 366 e-101
gi|83716024 kinesin family member 21B [Homo sapiens] 357 4e-98
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 305 2e-82
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 289 1e-77
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 289 1e-77
gi|71061468 centromere protein E [Homo sapiens] 288 3e-77
gi|4758646 kinesin family member 3B [Homo sapiens] 287 4e-77
gi|4758650 kinesin family member 5C [Homo sapiens] 282 1e-75
gi|45446749 kinesin family member 5A [Homo sapiens] 282 1e-75
gi|46852174 kinesin family member 3A [Homo sapiens] 270 5e-72
gi|4758648 kinesin family member 5B [Homo sapiens] 269 1e-71
gi|41352705 kinesin family member 3C [Homo sapiens] 268 4e-71
gi|9910266 kinesin family member 15 [Homo sapiens] 266 1e-70
gi|46852172 kinesin family member 13B [Homo sapiens] 250 8e-66
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 248 4e-65
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 248 4e-65
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 247 5e-65
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 247 5e-65
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 247 5e-65
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 247 5e-65
gi|40254834 kinesin family member 1C [Homo sapiens] 244 5e-64
gi|13699824 kinesin family member 11 [Homo sapiens] 239 2e-62
gi|148612831 kinesin family member 18A [Homo sapiens] 237 5e-62
gi|156616271 kinesin family member 19 [Homo sapiens] 236 1e-61
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 233 1e-60
gi|7661878 kinesin family member 14 [Homo sapiens] 221 4e-57
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 2737 bits (7094), Expect = 0.0
Identities = 1401/1401 (100%), Positives = 1401/1401 (100%)
Query: 1 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEV 60
MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEV
Sbjct: 1 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEV 60
Query: 61 YNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQS 120
YNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQS
Sbjct: 61 YNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQS 120
Query: 121 ISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAG 180
ISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAG
Sbjct: 121 ISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAG 180
Query: 181 EVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKF 240
EVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKF
Sbjct: 181 EVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKF 240
Query: 241 HFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITR 300
HFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITR
Sbjct: 241 HFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITR 300
Query: 301 LLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEME 360
LLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEME
Sbjct: 301 LLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEME 360
Query: 361 FEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFT 420
FEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFT
Sbjct: 361 FEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFT 420
Query: 421 FLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKR 480
FLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKR
Sbjct: 421 FLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKR 480
Query: 481 ELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIE 540
ELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIE
Sbjct: 481 ELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIE 540
Query: 541 QQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQD 600
QQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQD
Sbjct: 541 QQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQD 600
Query: 601 SRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTR 660
SRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTR
Sbjct: 601 SRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTR 660
Query: 661 CRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILT 720
CRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILT
Sbjct: 661 CRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILT 720
Query: 721 EAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQK 780
EAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQK
Sbjct: 721 EAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQK 780
Query: 781 QLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANE 840
QLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANE
Sbjct: 781 QLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANE 840
Query: 841 LEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDL 900
LEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDL
Sbjct: 841 LEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDL 900
Query: 901 DACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKE 960
DACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKE
Sbjct: 901 DACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKE 960
Query: 961 ALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQV 1020
ALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQV
Sbjct: 961 ALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQV 1020
Query: 1021 EVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQ 1080
EVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQ
Sbjct: 1021 EVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQ 1080
Query: 1081 KSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMK 1140
KSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMK
Sbjct: 1081 KSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMK 1140
Query: 1141 VLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYE 1200
VLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYE
Sbjct: 1141 VLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYE 1200
Query: 1201 DKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEE 1260
DKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEE
Sbjct: 1201 DKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEE 1260
Query: 1261 LKWASRPESMKLSGREREMDSSASSLRTQPNPQKLWEDIPELPPIHSSLAPPSGHMLGNE 1320
LKWASRPESMKLSGREREMDSSASSLRTQPNPQKLWEDIPELPPIHSSLAPPSGHMLGNE
Sbjct: 1261 LKWASRPESMKLSGREREMDSSASSLRTQPNPQKLWEDIPELPPIHSSLAPPSGHMLGNE 1320
Query: 1321 NKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGVTPVKLCRKELRQISALELSLRRSSLGV 1380
NKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGVTPVKLCRKELRQISALELSLRRSSLGV
Sbjct: 1321 NKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGVTPVKLCRKELRQISALELSLRRSSLGV 1380
Query: 1381 GIGSMAADSIEVSRKPRDLKT 1401
GIGSMAADSIEVSRKPRDLKT
Sbjct: 1381 GIGSMAADSIEVSRKPRDLKT 1401
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 915 bits (2364), Expect = 0.0
Identities = 581/1405 (41%), Positives = 846/1405 (60%), Gaps = 101/1405 (7%)
Query: 2 EEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVY 61
EE PV+VA+R+RPLL KE LH HQ C++V P +V +GRDR F F V +++ Q+ VY
Sbjct: 12 EEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVY 71
Query: 62 NTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQSI 121
C++PL+ + EG+NATVFAYGQTGSGKTYT+G +AS++E ++GI+PRA+ E F+ I
Sbjct: 72 QACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEAFKLI 131
Query: 122 SEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAGE 181
E+ +D V VSY+EVYKE+ RDLLE+ T+ +D+ +REDE+GN V+ G KE VE E
Sbjct: 132 DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLDE 191
Query: 182 VMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKFH 241
V+SLLEMGNAARHTG T +N SSRSH +FT+++ Q + + + +VSKFH
Sbjct: 192 VLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPA--PGQLLVSKFH 249
Query: 242 FVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITRL 301
FVDLAGSERV KTG+TGER KESIQINS LLALGNVISALGDP+R+ SHIPYRD+KITR+
Sbjct: 250 FVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRI 309
Query: 302 LKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEF 361
LKDSLGG+AKTVMI CVSPSSS+FDE+LN+L YA+RA+NIRN+ TVN+ PE++R E
Sbjct: 310 LKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERPPEET- 368
Query: 362 EIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTF 421
+ S+T I+R G + +L EC Y+ C + A++
Sbjct: 369 -----ASGARGPPRHRSETRIIHR-GRRAPGPATASAAAAMRLGAECARYRACTDAAYSL 422
Query: 422 LVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRE 481
L +L+ L K+++W ++ R A+ ++ G S Q ++E
Sbjct: 423 LRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVEDQAAQGAGGRKE 482
Query: 482 LKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQ 541
+ Q +L L+NQV + +EN+ +L++A + +LQ++++ EQ
Sbjct: 483 DEGAQQLLT---------------LQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQ 527
Query: 542 QLLVDQLSEELTKLNLSVT------SSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYI 595
Q EE+ +L L + + G P + +P RP+T P H + +
Sbjct: 528 Q-------EEMVELRLRLELVRPGWGGPRLLNGLPPGSFVP--RPHTAPLGGAHAHVLGM 578
Query: 596 PSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLH------CQFSDNSDDE 649
P D + G R + + E ++L S S++E
Sbjct: 579 ----------VPPACLPGDEV--GSEQRGEQVTNGREAGAELLTEVNRLGSGSSAASEEE 626
Query: 650 ESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQ------- 702
E E + T R+ I S + + + LE D I +
Sbjct: 627 EEEEEPPRRTLHLRRNRISNCSQRAGARPGSLPERKGPELCLEELDAAIPGSRAVGGSKA 686
Query: 703 ESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVT 762
Q + SE L +A+QK+REL INI+MKE+LI EL++TG A+++++Q+S ++
Sbjct: 687 RVQARQVPPATASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIR 746
Query: 763 KLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQ 822
+LE +AEQ + EL E Q+QL+ELE K+L D + +LQ EFR+++ AA+ +VQVL++K+Q
Sbjct: 747 ELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQ-EFRRRVAAAQSQVQVLKEKKQ 805
Query: 823 DSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKE 882
+++L SLS Q+EKR ELE++V M+ Q+ QLQR+LREE E++++L+A + + Q ++KE
Sbjct: 806 ATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKE 865
Query: 883 IQLKTGQEEG-LKPKAEDLDACNLKRRKGSFGSIDHL---QKLDEQKKWLDEEVEKVLNQ 938
++LK Q++ LK K E++ A KRR GS GS+ L QK++EQKKWLD+E+EKVL Q
Sbjct: 866 LELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQ 925
Query: 939 RQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQEL 998
R+ LEEL +L KREAI++KKEAL+QEK+ LE+K+LRSSQALN D +++S+RL LE+EL
Sbjct: 926 RRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKEL 985
Query: 999 SEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQL 1058
SEK+ QL+ +A+ + +I +++ L++EKD L K+R +D KL+ G +LSPEEE LFQL
Sbjct: 986 SEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQL 1045
Query: 1059 EEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFN 1118
+E IEAL+AAIEY+NE+I RQ+ LRAS LS+ E N++ KL+ LS E R +L +YF+
Sbjct: 1046 DEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFD 1105
Query: 1119 KVVNLREAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQ 1178
KVV LRE + +QQ+ E++M++ E+ +V LE AL+ +L+ DR+LTLQQKEHEQ MQ
Sbjct: 1106 KVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQ 1165
Query: 1179 LLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKL--KELVGEA---IR 1233
LLL ++ GEG+ ++ + YE +IQ LEK+L Y +++ K+KL VG + +
Sbjct: 1166 LLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGVNAVGHSRGGEK 1225
Query: 1234 RQLAPSEYQEAGDGVLKPEGGGMLSEELKWASRPESMKLSGREREMDSSASSLRTQPNPQ 1293
R L Q G+ E L+ EL W S RE D L P P
Sbjct: 1226 RSLCSEGRQAPGN-----EDELHLAPELLWLSPLTEGAPRTREETRD-----LVHAPLP- 1274
Query: 1294 KLWEDIPELPPIHSSLAPPSGHMLGNENKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGV 1353
W+ SSL E + ++ + ++ L ++ VG G
Sbjct: 1275 LTWK--------RSSLC--------GEEQGSPEELRQREAAEPLVGRVLPVGEAGLPWNF 1318
Query: 1354 TPVKLCRKELRQISALELSLRRSSL 1378
P+ R+ELR+ S + +R++ L
Sbjct: 1319 GPLSKPRRELRRASPGMIDVRKNPL 1343
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 372 bits (956), Expect = e-102
Identities = 319/1120 (28%), Positives = 533/1120 (47%), Gaps = 195/1120 (17%)
Query: 4 IPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYNT 63
IPV+VA+R RPL+ KE Q+C+ +P QV++G D+ FT+DFVF ++ Q+EV+NT
Sbjct: 8 IPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNT 67
Query: 64 CIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVV-EGQKGIIPRAIQEIFQSIS 122
+ PL+ + +GYNATV AYGQTGSGKTY++GG + A E G+IPR IQ +F+ I
Sbjct: 68 AVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEID 127
Query: 123 EHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAGEV 182
+ +F +KVSY+E+Y E++ DLL ++IRED K IVG E V A +
Sbjct: 128 KKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDT 187
Query: 183 MSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKFHF 242
+S LE GN +R +T MN SSRSHAIFTIS+ Q K+ + + SK H
Sbjct: 188 VSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSS---------FRSKLHL 238
Query: 243 VDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITRLL 302
VDLAGSER KT G+R KE I IN GLL LGNVISALGD + K +PYRD+K+TRLL
Sbjct: 239 VDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDK-KGGFVPYRDSKLTRLL 297
Query: 303 KDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFE 362
+DSLGG++ T+MI CVSP+ SN +E+LN+L+YA+RAR I+NKP VN P++ ++ ++ +
Sbjct: 298 QDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQ 357
Query: 363 IKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFL 422
++ L + L Q G + I E S + + SL E+ Q VEE
Sbjct: 358 VQQL-QVLLLQAHGGTLPGSITVEPSEN---LQSLMEK----------NQSLVEE----- 398
Query: 423 VDLKDTVRLNEKQQHKLQEWFNMI-QEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRE 481
NEK L E Q + + +LT A LEE QH
Sbjct: 399 ---------NEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAA------- 442
Query: 482 LKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQ 541
C L ++V + LE +ELK V++ I
Sbjct: 443 -----CKLDLQKLV---ETLEDQELKENVEI-------------------------ICNL 469
Query: 542 QLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDS 601
Q L+ QLS+E + +A E + PE + F T H +
Sbjct: 470 QQLITQLSDETVACMAAAIDTAVEQ--EAQVETSPETSRSSDAFTTQ--HAL-------- 517
Query: 602 RKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRC 661
R+ S + L++ A ++ + + + Q + + Q+ DN + E
Sbjct: 518 RQAQMSKELVELNKALALKEALARKMTQN-DSQLQPIQYQYQDNIKELE----------- 565
Query: 662 RSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQES-QELNLQKLKNSERILT 720
+E+ + Q E ++ LE + K D Q E ++L+ E +
Sbjct: 566 ---------------LEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIA 610
Query: 721 EAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQK 780
+ K+K+ E + +K+KE + + K + + + Q + +++ DAE+ + + K
Sbjct: 611 DLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDK 670
Query: 781 QLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQV-------LQKKQQDSKKLASLSIQ 833
++ +L+ +D +KL++ F+K+ + + + + L+ Q +++A +
Sbjct: 671 EVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKE 730
Query: 834 NEKRA-------------NELE-----------------------QSVDHMKYQKI---- 853
+ R NE+E Q V +K +K
Sbjct: 731 TQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGEN 790
Query: 854 ---QLQRKLREENEKRKQL----DAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLK 906
+L+R+ E R Q+ D++ K+ + E++ ++ Q L+ K D ++ +
Sbjct: 791 PPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRP 850
Query: 907 RRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKK-REAIVSKKEALLQE 965
+++ +++ + E K L + ++++ + ++ +LE+ LK+ + + ++ L +E
Sbjct: 851 KQRW-----ENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEE 905
Query: 966 KSH-------LENKKLRSSQALNTDSLKISTRLNL-------LEQELSEKNVQLQTSTAE 1011
++H L+ + +R Q L + ++L LE+ +SEK QL ++
Sbjct: 906 RNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKC 965
Query: 1012 EKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEE 1051
+ ++ + EV + + QL + + +KL +V S ++
Sbjct: 966 QDEELEKMREVCE-QNQQLLRENEIIKQKLTLLQVASRQK 1004
Score = 92.8 bits (229), Expect = 2e-18
Identities = 119/572 (20%), Positives = 250/572 (43%), Gaps = 78/572 (13%)
Query: 673 VCSLVEL-SDTQDETQKSDLENEDLKIDCLQESQ-ELNLQKLKNSERILTE-------AK 723
+C+L +L + DET D ++ QE+Q E + + ++S+ T+
Sbjct: 466 ICNLQQLITQLSDETVACMAAAIDTAVE--QEAQVETSPETSRSSDAFTTQHALRQAQMS 523
Query: 724 QKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQ 783
+++ EL + +KE L +++ + + + + QY + +LE +E+I QK+ +
Sbjct: 524 KELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELE-------LEVINLQKEKE 576
Query: 784 EL--ENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANEL 841
EL E + A + KL + RK++ + ++ L+KK + KL L E+ ++L
Sbjct: 577 ELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKL 636
Query: 842 EQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLD 901
Q + MK Q++QL R+++E+ EK +Q ++ ++KE K Q E LK +
Sbjct: 637 NQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKR-QYELLKLERNFQK 695
Query: 902 ACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLK-----KREAIV 956
N+ RRK + + + D +K + ++ Q + +E A +K + E +V
Sbjct: 696 QSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMV 755
Query: 957 SKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKI 1016
S +EA LE++K+ A++ ++
Sbjct: 756 STEEAKRHLNDLLEDRKI----------------------------------LAQDVAQL 781
Query: 1017 SEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESI 1076
E+ E + +L++R ++ E G+V E+ + + IE+LE +E+R+ I
Sbjct: 782 KEKKESGENPPPKLRRRTFSLTE--VRGQVSESED-----SITKQIESLETEMEFRSAQI 834
Query: 1077 QN-RQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNE 1135
+ +QK L A + + E +A + +E + L ++V+ + K + +
Sbjct: 835 ADLQQKLLDAESEDRPKQR---WENIATI--LEAKCALKYLIGELVSSKIQVSKLESSLK 889
Query: 1136 EMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMET 1195
+ K + M+ E + ++ + L +++H++K+ LL ++
Sbjct: 890 QSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQS-----QMA 944
Query: 1196 FKTYEDKIQQLEKDLYFYKKTSRDHKKKLKEL 1227
K E+ + + E+ L K + +K++E+
Sbjct: 945 EKQLEESVSEKEQQLLSTLKCQDEELEKMREV 976
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 368 bits (945), Expect = e-101
Identities = 306/1099 (27%), Positives = 514/1099 (46%), Gaps = 170/1099 (15%)
Query: 2 EEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVY 61
+E V+VAVRIRP L KE + +C V P QV +G+D+ FTFD+VF +S Q+++Y
Sbjct: 6 DESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIY 65
Query: 62 NTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQSI 121
CI+ L+ EGYNATVFAYGQTG+GKTYT+G G ++VE + GII RA++ +F+SI
Sbjct: 66 IQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKSI 125
Query: 122 SEH---------PSIDFNVKVSYIEVYKEDLRDL------LELETSMKDLHIREDEKGNT 166
E P+ DF V ++E+Y E++ DL ++ ++ ++ I ED G
Sbjct: 126 EEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGI 185
Query: 167 VIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVH------- 219
VG V + E+M L++G +R T +TQMN SSRSHAIFTI +CQ
Sbjct: 186 YTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDA 245
Query: 220 ----KNMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALG 275
N +E + +KFHFVDLAGSER+ +TG TGER KE I IN GLLALG
Sbjct: 246 DNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALG 305
Query: 276 NVISALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYA 335
NVISALGD ++++H+PYRD+K+TRLL+DSLGG+++T+MI CVSPS +F E+LN+LKYA
Sbjct: 306 NVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYA 365
Query: 336 NRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAG---------------VSQT 380
NRARNI+NK VN S +I+ + EI L+ L + G +
Sbjct: 366 NRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHEN 425
Query: 381 TQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQ 440
+ E + RI +++E V L+ Q ++A L + NE+ + +
Sbjct: 426 AMLQTENNNLRVRIKAMQETVDALRSRIT--QLVSDQANHVLARAGEG---NEEISNMIH 480
Query: 441 EWFNMIQEVRKAVLTS--------------------FRGIG--GTASLEEGPQHVTVLQL 478
+ I+++R +L S F G L + + ++ L
Sbjct: 481 SYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL 540
Query: 479 -KRELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEK 537
K++L+K + + +K + KE +E KG VS +E ++ ++++
Sbjct: 541 AKKDLEKLK-----RKEKRKKKSVAGKEDNTDTDQEKKEEKG--VSERENNELEVEESQE 593
Query: 538 IIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPY-----TVPFDTHLGHY 592
+ + + ++ EE ++ +S D D+ E+ Y + + +
Sbjct: 594 VSDHEDEEEEEEEEEDDIDGGESS-------DESDSESDEKANYQADLANITCEIAIKQK 646
Query: 593 IYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESE 652
+ +++ T Y + + R L E+D+VL N ES
Sbjct: 647 LIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQL-----ERDQVL-----QNLGSVESY 696
Query: 653 GQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKL 712
+EK+ + E +K L+ + ++ LQ +Q+ + + L
Sbjct: 697 SEEKA----------------------KKVRSEYEKK-LQAMNKELQRLQAAQKEHARLL 733
Query: 713 KNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQA- 771
KN + + K+ +++ K K L+K++ + A+ + + ++ +L+ D +
Sbjct: 734 KNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRD 793
Query: 772 -KVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASL 830
++ L+E QK+ QE+ + RK + LR QV + + K+
Sbjct: 794 HQLRLLEAQKRNQEVVLR---------------RKTEEVTALRRQVRPMSDKVAGKVTRK 838
Query: 831 SIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQE 890
++ A + S + + DA QQK++ + +
Sbjct: 839 LSSSDAPAQDTGSSAAAV-------------------ETDASRTGAQQKMR---IPVARV 876
Query: 891 EGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEAD-- 948
+ L A + + +RKG G + + + + L+ V ++ Q+ + +EAD
Sbjct: 877 QALPTPATNGNR-KKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMN 935
Query: 949 --LKKREAIVSKKEAL--LQEKSHLENKKLRSSQA-LNTDSLKISTRLNLLEQELSEKNV 1003
LK+RE + ++E L +EK EN + + A +N + ++ ++ + +S+
Sbjct: 936 RLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISD--C 993
Query: 1004 QLQTSTAEEKTKISEQVEV 1022
Q EE + E ++V
Sbjct: 994 QANIMQMEEAKEEGETLDV 1012
Score = 116 bits (291), Expect = 1e-25
Identities = 139/561 (24%), Positives = 261/561 (46%), Gaps = 55/561 (9%)
Query: 644 DNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQE 703
DN+D ++ + +EK G R + ++ +S E+SD +DE ++ + E +D ID +
Sbjct: 564 DNTDTDQEKKEEK-GVSERENNELEVEESQ----EVSDHEDEEEEEEEEEDD--IDGGES 616
Query: 704 SQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTK 763
S E + + + E+ +A + +T I +K+ LI EL + +++ KQY K+
Sbjct: 617 SDESDSE---SDEKANYQAD--LANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMM 671
Query: 764 LEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQD 823
L+H ++E + + L +E+ S+ K K++ E+ KK+ A +Q LQ Q++
Sbjct: 672 LQHKIRDTQLERDQVLQNLGSVES--YSEEKAK-KVRSEYEKKLQAMNKELQRLQAAQKE 728
Query: 824 SKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEK-------RKQLDAVIKRD 876
+L Q EK+ +L+Q V MK K++L ++++EE EK R + A +K+D
Sbjct: 729 HARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKD 788
Query: 877 QQKIKEIQL------KTGQEEGLKPKAEDLDACNLKRRKGS---FGSIDHLQKLDEQKKW 927
Q+K ++ QL K QE L+ K E++ A + R S G + +KL
Sbjct: 789 QRK-RDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKV--TRKLSSSDAP 845
Query: 928 LDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKI 987
+ + A K R V++ +AL ++ KK + +
Sbjct: 846 AQDTGSSAAAVETDASRTGAQQKMR-IPVARVQALPTPATNGNRKKYQRKGLTGRVFISK 904
Query: 988 STRL--NLLEQELSEKNVQLQT--STAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKN 1043
+ R+ LLE+ +++ +Q T + + ++ +Q E L K +++L KRR + + +N
Sbjct: 905 TARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVK--EN 962
Query: 1044 GRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEA-NVLEKLA 1102
G E + + + E +E+L A I+Y N+SI + Q ++ GE +V +
Sbjct: 963 G-----EGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVIN 1017
Query: 1103 CLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQC 1162
+ E R +L + + +N + Q +E ++KVLE E+ SA + Q
Sbjct: 1018 ACTLTEARYLLDHFLSMGIN-----KGLQAAQKEAQIKVLEGRLKQTEITSATQN---QL 1069
Query: 1163 DRRLTLQQKEHEQKMQLLLHH 1183
+ ++ E ++ LL H
Sbjct: 1070 LFHMLKEKAELNPELDALLGH 1090
Score = 45.8 bits (107), Expect = 3e-04
Identities = 79/432 (18%), Positives = 177/432 (40%), Gaps = 46/432 (10%)
Query: 679 LSDTQDETQKSDLENEDLK--IDCLQESQELNLQKLKN-----SERILTEAKQKMRELT- 730
++D E EN +L+ I +QE+ + ++ + +L A + E++
Sbjct: 418 INDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISN 477
Query: 731 ---INIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELEN 787
IK EDL +L+++ +++ K + + + + + + +E
Sbjct: 478 MIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEI 537
Query: 788 KDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDH 847
DL+ ++ +KE RKK A +++ +K S NE E ++ DH
Sbjct: 538 IDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDH 597
Query: 848 MKYQKIQLQR-------KLREENEKRKQLDAVIKRD-----------QQKIKEIQLKTGQ 889
++ + + + +E++ A + D Q+ I E++ +
Sbjct: 598 EDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKR 657
Query: 890 EEGLKPKAED-LDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQ-RQELEELEA 947
+ LK + E+ L K R LQ L + + +E+ +KV ++ ++L+ +
Sbjct: 658 LQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNK 717
Query: 948 DLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQT 1007
+L++ +A + LL+ +S E K+L+ Q +++E + ++ + Q
Sbjct: 718 ELQRLQAAQKEHARLLKNQSQYE-KQLKKLQQ------------DVMEMKKTKVRLMKQM 764
Query: 1008 STAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEA 1067
+EK +++E +E QL+K + D +L+ +E VL + E + AL
Sbjct: 765 KEEQEKARLTESRR--NREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRR 822
Query: 1068 AIEYRNESIQNR 1079
+ ++ + +
Sbjct: 823 QVRPMSDKVAGK 834
Score = 44.3 bits (103), Expect = 8e-04
Identities = 67/317 (21%), Positives = 146/317 (46%), Gaps = 41/317 (12%)
Query: 929 DEEVEKVLNQR-QELEELEADLKKREAIVSKKEALLQEKS----HLENKKLRSSQALNTD 983
+EE+ +++ +E+E+L A L + EA+ L + + S L++D
Sbjct: 472 NEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSD 531
Query: 984 SLKISTRLNLLEQELS-----EKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVD 1038
I ++L +++L EK + + E+ T ++ +KE+ + +R +N
Sbjct: 532 KETIEI-IDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQE----KKEEKGVSERENNEL 586
Query: 1039 EKLKNGRVLSPEEEHVLFQLEEG-IEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANV 1097
E ++ V E+E + EE I+ E++ E +ES + + + +A N++ E +
Sbjct: 587 EVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSES--DEKANYQADLANITC-EIAI 643
Query: 1098 LEKLACL---SPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESA 1154
+KL S ++T+ +Y K++ L+ R QL ERD +++ L S
Sbjct: 644 KQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQL----------ERDQVLQNLGSV 693
Query: 1155 LDHLKLQCDRRLTLQQKEHEQKMQLLLHHFK-----EQDGEGIMETFKTYEDKIQQLEKD 1209
+ + + + E+E+K+Q + + +++ +++ YE ++++L++D
Sbjct: 694 ESY----SEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQD 749
Query: 1210 LYFYKKTSRDHKKKLKE 1226
+ KKT K++KE
Sbjct: 750 VMEMKKTKVRLMKQMKE 766
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 366 bits (940), Expect = e-101
Identities = 322/1073 (30%), Positives = 510/1073 (47%), Gaps = 136/1073 (12%)
Query: 4 IPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYNT 63
IPV+VA+R RPL+ KE Q+C+ +P QV++G D+ FT+DFVF + Q+EV+N
Sbjct: 8 IPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNK 67
Query: 64 CIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVV-EGQKGIIPRAIQEIFQSIS 122
+ PL+ + +GYNATV AYGQTGSGKTY++GG + A E GIIPR IQ +F+ I
Sbjct: 68 AVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEID 127
Query: 123 EHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAGEV 182
+ +F +KVSY+E+Y E++ DLL ++IRED K IVG E V A +
Sbjct: 128 KKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDT 187
Query: 183 MSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKFHF 242
+S LE GN +R +T MN SSRSHAIFTISI Q K+ + SK H
Sbjct: 188 VSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCS---------FRSKLHL 238
Query: 243 VDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITRLL 302
VDLAGSER KT G+R KE I IN GLL LGNVISALGD +K S +PYRD+K+TRLL
Sbjct: 239 VDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDD-KKGSFVPYRDSKLTRLL 297
Query: 303 KDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFE 362
+DSLGG++ T+MI CVSP+ SN +E+L++L+YA+RAR I+NKP VN P + ++ ++ +
Sbjct: 298 QDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQ 357
Query: 363 IKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFL 422
++ L + L Q G + IN E S + SL E+ L E C+ +A
Sbjct: 358 VQQL-QVLLLQAHGGTLPGSINAEPS---ENLQSLMEKNQSLVEENEKLSRCLSKAAGQT 413
Query: 423 VDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKREL 482
+ + + L E+ KL A LEE QHV
Sbjct: 414 AQMLERIILTEQVNEKL-----------------------NAKLEELRQHVA-------- 442
Query: 483 KKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQ 542
C L ++V + LE +ELK V++ I Q
Sbjct: 443 ----CKLDLQKLV---ETLEDQELKENVEI-------------------------ICNLQ 470
Query: 543 LLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSR 602
L+ QLS+E + +A E + PE + F T H ++ Q S+
Sbjct: 471 QLITQLSDETVACTAAAIDTAVEE--EAQVETSPETSRSSDAFTTQ--HALH--QAQMSK 524
Query: 603 KVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCR 662
+V +L T++ + Q + + Q+ DN + E E +
Sbjct: 525 EVVELNNALALKEALVRKMTQN-------DNQLQPIQFQYQDNIKNLELEVINLQKEKEE 577
Query: 663 SRSWIQKPDSVCSLVELSDTQDE-TQKSDLENEDLKIDCLQESQELNLQKLKNSERILTE 721
+Q + +LS+ + + Q+ + + DLK ++S+ L L+ +++ER +++
Sbjct: 578 LVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLK--ESTERTVSK 635
Query: 722 AKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIET--- 778
Q E+ + + L++++ + + ++ +V +L+ + + EL++
Sbjct: 636 LNQ---EIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERN 692
Query: 779 -QKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKR 837
QKQ L K A +L+ +K+ + R ++ Q K+ + ++N
Sbjct: 693 FQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKR----KETQSHGKEGIAARVRN-WL 747
Query: 838 ANELEQSV----------DHMKYQKIQLQR--KLREENEKRKQLDAVIKRDQQKIKEIQL 885
NE+E V D ++ +KI Q +L+E+ E R+ +++ + E+
Sbjct: 748 GNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHG 807
Query: 886 KTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEEL 945
+ + E K + ++ R Q D Q+K LD E E +Q E +
Sbjct: 808 QVLESEDCITKQIESLETEMELRSA--------QIADLQQKLLDAESED--RPKQCWENI 857
Query: 946 EADLKKREAIVSKKEALLQEKSH---LENKKLRSSQALNTDSLKI----STRLNLLEQEL 998
L+ + A+ L+ K H LEN LR S+A D K+ + +E EL
Sbjct: 858 ATILEAKCALKYLIGELVSSKIHVTKLEN-SLRQSKASCADMQKMLFEEQNHFSEIETEL 916
Query: 999 SEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEE 1051
+ V+++ E+ + Q++ Q + QL+K +++L + EE
Sbjct: 917 QAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEE 969
Score = 87.8 bits (216), Expect = 7e-17
Identities = 141/642 (21%), Positives = 277/642 (43%), Gaps = 101/642 (15%)
Query: 673 VCSLVEL-SDTQDETQKSDLENEDLKIDCLQESQ-ELNLQKLKNSERILTE-------AK 723
+C+L +L + DET D ++ +E+Q E + + ++S+ T+
Sbjct: 466 ICNLQQLITQLSDETVACTAAAIDTAVE--EEAQVETSPETSRSSDAFTTQHALHQAQMS 523
Query: 724 QKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQ 783
+++ EL + +KE L++++ + N + + QY + LE +E+I QK+ +
Sbjct: 524 KEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLE-------LEVINLQKEKE 576
Query: 784 EL--ENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANEL 841
EL E + + KL + K + + ++ L+KK + KL L E+ ++L
Sbjct: 577 ELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKL 636
Query: 842 EQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKE-IQLKTGQEEGLKPKAEDL 900
Q + MK Q++QL R+++E+ EK +Q Q+K KE IQLK
Sbjct: 637 NQEIWMMKNQRVQLMRQMKEDAEKFRQW------KQKKDKEVIQLKE------------- 677
Query: 901 DACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKE 960
+ RK + + + +Q L R++ EE A K+ K+
Sbjct: 678 -----RDRKRQYELLKLERNFQKQSSVL----------RRKTEEAAAANKR------LKD 716
Query: 961 ALLQEKSHLENKKLRSSQALNTDSLKISTRL-NLLEQELSEKNVQLQTSTAEEKTKISEQ 1019
AL +++ + +K S + ++ L N +E +S + + + E KI Q
Sbjct: 717 ALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQ 776
Query: 1020 VEVLQKEKDQLQKRRHNVDEKLK---------NGRVLSPEEEHVLFQLEEGIEALEAAIE 1070
V KEK ++ R N KL+ +G+VL E+ + + IE+LE +E
Sbjct: 777 DVVQLKEK---KESRENPPPKLRKCTFSLSEVHGQVLESED-----CITKQIESLETEME 828
Query: 1071 YRNESIQN-RQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERK 1129
R+ I + +QK L A + + E +A + +E + L ++V+ + K
Sbjct: 829 LRSAQIADLQQKLLDAESEDRPK---QCWENIATI--LEAKCALKYLIGELVSSKIHVTK 883
Query: 1130 QQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKE-QD 1188
+ + K + M+ E ++ ++ + L +++H++K+ L+ +E Q
Sbjct: 884 LENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQM 943
Query: 1189 GEGIMETFKTYEDKIQQL-------EKDLYFYKKTSRDHKKKLKE---LVGEAIRRQLAP 1238
E +E K+ +K QQL +++L ++ +++ L+E + + I Q+A
Sbjct: 944 AEKQLE--KSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVAS 1001
Query: 1239 SEYQEAGDGVLKPEGGGMLSEELKWASRPESMKLSGREREMD 1280
+ D +L P+ E + +P +K E+ MD
Sbjct: 1002 RQKHLPNDTLLSPDSS---FEYIPPKPKPSRVKEKFLEQSMD 1040
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 357 bits (916), Expect = 4e-98
Identities = 319/1162 (27%), Positives = 520/1162 (44%), Gaps = 177/1162 (15%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYNTCI 65
VKVAVRIRP L KE + +C V P QV++G+D+ FT+DFVF ++ Q+++Y+TC+
Sbjct: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCV 68
Query: 66 KPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQSISEHP 125
L+ EGYNATV AYGQTG+GKTYT+G G + E ++GIIPRAI +F I+E
Sbjct: 69 SKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLFGGIAERK 128
Query: 126 ---------SIDFNVKVSYIEVYKEDLRDLLELETSMKDLH------IREDEKGNTVIVG 170
+F V ++E+Y E++ DL + H I ED G G
Sbjct: 129 RRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGIYTTG 188
Query: 171 AKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQ---------VHKN 221
+ S E++ L+ G +R T +TQMN SSRSHAIFTI +CQ V++
Sbjct: 189 VTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDLVNEA 248
Query: 222 MEAAEDGSWYSPRH--IVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVIS 279
+ DG+ S + + +KFHFVDLAGSER+ +TG TGER KE I IN GLLALGNVIS
Sbjct: 249 VTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVIS 308
Query: 280 ALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRAR 339
ALGD +K H+PYRD+K+TRLL+DSLGG+++T+MI CVSPS +F E+LN+LKYANRAR
Sbjct: 309 ALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRAR 368
Query: 340 NIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAG---------------VSQTTQIN 384
NI+NK VN S +I + EI L+ L +AG + +
Sbjct: 369 NIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQ 428
Query: 385 REGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFN 444
+E R+ +++E + + Q +EA L D NE +Q +
Sbjct: 429 KENGALRLRVKAMQEAIDAINNRVT--QLMSQEANLLLAKAGDG---NEAIGALIQNYIR 483
Query: 445 MIQEVRKAVLTS---------------------------FRGIGGTASLEEGPQHVTVLQ 477
I+E+R +L S GG+ + + +
Sbjct: 484 EIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRR 543
Query: 478 LKRELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEK 537
K++L++ L EV +K E + K + ++ Q+ EA++ ++E
Sbjct: 544 AKQDLER----LKKKEVRQRRKSPEKEAFKKRAKL--QQENSEETDENEAEEEEEERDES 597
Query: 538 IIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFD-------THLG 590
E++ + E+ S ++E+ D PE + D +
Sbjct: 598 GCEEEEGREDEDED---------SGSEESLVDSDSD--PEEKEVNFQADLADLTCEIEIK 646
Query: 591 HYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEE 650
+ R++ T Y I + R L E+D+VL N E
Sbjct: 647 QKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQL-----ERDRVL-----QNLSTME 696
Query: 651 SEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQ 710
+EK+ K D L E++ + Q + E+ L
Sbjct: 697 CYTEEKANK--------IKADYEKRLREMNRDLQKLQAAQKEHARL-------------- 734
Query: 711 KLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKL--EHDA 768
LKN R E K+ E+ K K L+K++ + + V + + ++ +L E
Sbjct: 735 -LKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRR 793
Query: 769 EQAKVELIETQKQLQELE-NKDLSDVAMKVKLQKEFRKKM-DAAKLRVQVLQKKQQDSKK 826
++ ++ +E+QK+ QE+ + +V+ +L K +++ A L+ +L + S
Sbjct: 794 QEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSAS 853
Query: 827 LASLSIQNEKRA-----NELEQSVDHM-----------------KYQK------IQLQRK 858
S ++ R+ + + ++H K+QK +
Sbjct: 854 TTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAAR 913
Query: 859 LREENEKRKQLDAVIKR--------DQQK-IKEIQLKTGQEEGLKPKAEDLDACNLKRRK 909
L+ ++ +R+ +D V++R D ++ IK+ + +E L+ K E L A + + K
Sbjct: 914 LKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEEEK 973
Query: 910 GSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHL 969
G + ++ L ++++ + +LEE + +L + V L E L
Sbjct: 974 GLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLL 1033
Query: 970 ENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQ 1029
+ L++S + ++ LLE L + ++ + + E+ E +
Sbjct: 1034 LDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREKAEA----HPE 1089
Query: 1030 LQKRRHNVDEKLKNGRVLSPEE 1051
LQ +NV + +NG + EE
Sbjct: 1090 LQALIYNVQQ--ENGYASTDEE 1109
Score = 94.0 bits (232), Expect = 9e-19
Identities = 122/574 (21%), Positives = 246/574 (42%), Gaps = 77/574 (13%)
Query: 643 SDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQ 702
S+ +D+ E+E +E+ ++ +S C E +DE + S E + D
Sbjct: 579 SEETDENEAEEEEE-----------ERDESGCE--EEEGREDEDEDSGSEESLVDSDSDP 625
Query: 703 ESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVT 762
E +E+N Q + +LT I++K+ LI EL + +++ QY K+
Sbjct: 626 EEKEVNFQA-------------DLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLI 672
Query: 763 KLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQ 822
L++ + +E + LQ L + K++ ++ K++ +Q LQ Q+
Sbjct: 673 LLQNKIRDTQ---LERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQK 729
Query: 823 DSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRD------ 876
+ +L + E+ +L+ V MK K+ L +++REE ++R+ ++ R+
Sbjct: 730 EHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKK 789
Query: 877 QQKIKEIQL------KTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDE 930
+Q+ +E Q+ K QE L+ K +++ A RR S + + LD
Sbjct: 790 EQRRQEFQIRALESQKRQQEMVLRRKTQEVSAL---RRLAKPMSERVAGRAGLKPPMLDS 846
Query: 931 EVEKVLNQRQELEELEADLKKREAIVSKKEALLQE-----------KSHLENKKLRSSQA 979
E ++ E E+ + +IV + + + KK + A
Sbjct: 847 GAE--VSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGA 904
Query: 980 LNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDE 1039
+ S + LE+ + + +Q T + +E L K++++L + +
Sbjct: 905 SQSFSKAARLKWQSLERRIIDIVMQRMTIV-----NLEADMERLIKKREELFLLQEALRR 959
Query: 1040 KLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKS---LRASFHNLSRGEAN 1096
K + + SPEEE L +L E IE L A I+Y N+ I + Q + L + L + +
Sbjct: 960 KRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTS 1019
Query: 1097 VLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLE-RDNMVRELESAL 1155
V+ ++ S E R +L + + ++ Q+ +E ++++LE R S+
Sbjct: 1020 VV--ISSCSLAEARLLLDNFLKASI-----DKGLQVAQKEAQIRLLEGRLRQTDMAGSSQ 1072
Query: 1156 DHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDG 1189
+HL L R ++ E ++Q L+++ ++++G
Sbjct: 1073 NHLLLDALR----EKAEAHPELQALIYNVQQENG 1102
Score = 40.0 bits (92), Expect = 0.016
Identities = 63/286 (22%), Positives = 120/286 (41%), Gaps = 37/286 (12%)
Query: 995 EQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLS------ 1048
E+E +K +LQ +EE + + E ++++ ++ DE +G S
Sbjct: 564 EKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDS 623
Query: 1049 -PEEEHVLFQLEEGIEALEAAIEYR-NESIQNRQKSLRASFHNLSRGEANVLEKLACLSP 1106
PEE+ V FQ + E I+ + + ++N Q+ L+ H EKL L
Sbjct: 624 DPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYE-------EKLILLQN 676
Query: 1107 VEIRTILFRYFNKVVNLRE----AERKQQLYNEEMKMKVLERDNMVRELESA-LDHLKL- 1160
+IR + NL E K + + ++ E + +++L++A +H +L
Sbjct: 677 -KIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLL 735
Query: 1161 ----QCDRRLTLQQKE----HEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYF 1212
+ +R L Q E + K+ L+ +EQ ++ET + E + E+
Sbjct: 736 KNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQE 795
Query: 1213 YKKTSRDHKKKLKELV-------GEAIRRQLAPSEYQEAGDGVLKP 1251
++ + + +K+ +E+V A+RR P + AG LKP
Sbjct: 796 FQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKP 841
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 305 bits (782), Expect = 2e-82
Identities = 353/1307 (27%), Positives = 575/1307 (43%), Gaps = 223/1307 (17%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRV-----------IPNSQQVIIGRDRV--FTFDFVFG 52
VKVAVR+RP+ +E + +++ IP GR+R FT+DF F
Sbjct: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
Query: 53 KNST-------QDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEG 105
T Q+ V+ T +V S EGYNA VFAYGQTGSGK+YT+ G G
Sbjct: 64 SADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGN------SG 117
Query: 106 QKGIIPRAIQEIFQSISEHPSID---FNVKVSYIEVYKEDLRDLLELETSMK-DLHIRED 161
G+IPR + +F I+E D F +VSY+E+Y E +RDLL ++S +L +RE
Sbjct: 118 DSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREH 177
Query: 162 EKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKN 221
K + + V++ G+V L++ GN R T T MN+ SSRSHAIFTI Q +
Sbjct: 178 PKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFD 237
Query: 222 MEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISAL 281
E P VSK H VDLAGSER TG TG R KE IN L+ LGNVISAL
Sbjct: 238 SEM--------PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISAL 289
Query: 282 GD---------PRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSL 332
D ++K +PYRD+ +T LLKDSLGG++KT+MI +SP+ N+ E+L++L
Sbjct: 290 ADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTL 349
Query: 333 KYANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTN 392
+YANRA+NI NKPT+N I E+ EI L+ L +Q QI SP
Sbjct: 350 RYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLL-------AQGNQIALLDSPTA- 401
Query: 393 RIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKA 452
S+EE++ Q + R+ E + +W N Q + K
Sbjct: 402 --LSMEEKLQQ-----------------------NEARVQELTKEWTNKW-NETQNILKE 435
Query: 453 VLTSFRGIGGTASLEEGPQHVTVLQ--------LKRELKKCQCVLAADEVVFNQKELEVK 504
+ R G L+ H+ + + LK+ Q + D+ ++++ +
Sbjct: 436 QTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDD-ASTEQDIVLH 494
Query: 505 ELKNQVQMMVQENKGHAVSLKEAQ----KVNRLQNEKIIEQQLLVDQLSEELTKLNLSVT 560
L + + + EN G V+L VN +Q I+E L L + N+
Sbjct: 495 GLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQ---IVEATHLNQGAVILLGRTNMFRF 551
Query: 561 SSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGF 620
+ KE A++ E+R + L SR++ V P +R
Sbjct: 552 NHPKE------AAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFER----- 600
Query: 621 RTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSG----TRCRSRSWIQKPDSVCSL 676
+ + L +E + K++ EE E ++KS R + Q+ ++
Sbjct: 601 --QQREELEKLESKRKLI----------EEMEEKQKSDKAELERMQQEVETQRKETEIVQ 648
Query: 677 VELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMK 736
+++ ++ ++ E+ D L E ++ ++L+ + I + K++ E + ++ +
Sbjct: 649 LQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEE 708
Query: 737 EDLIKELIKTGNDAKSVSKQYSLKVTKL--EHDAEQAKVELIETQKQLQELENKDLSDVA 794
+KEL N+ K+ Q ++ +L E D + AK+EL + + LE ++ V
Sbjct: 709 LQRLKEL---NNNEKAEKFQIFQELDQLQKEKDEQYAKLEL-----EKKRLEEQEKEQVM 760
Query: 795 MKVKLQKEFRKKMDAAKL----RVQVLQKKQQDSKKL-ASLSIQNEKRANELEQSVDHMK 849
+ L+++ R+K + +L VQ ++++++D + + SL E RA E + K
Sbjct: 761 LVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEK 820
Query: 850 YQKIQLQRKLREENEKRKQLDAVI--KRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKR 907
Q LR KR+QL ++ ++D + K+I K QEE E L+ +
Sbjct: 821 AQ-------LRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEE-----QEILECLKCEH 868
Query: 908 RKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQE-- 965
K S +L E+ DE V V Q+ E+ +K E + KE LQ
Sbjct: 869 DKES--------RLLEKH---DESVTDVTEVPQDFEK----IKPVEYRLQYKERQLQYLL 913
Query: 966 KSHLE---NKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQ------------TSTA 1010
++HL +K R+ + L+ L + L +E+E+ EK QL +T
Sbjct: 914 QNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATF 973
Query: 1011 EEKTKISEQVE-VLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAI 1069
E I+ Q E V +KEK+ L+ R E L E L +LE AL+
Sbjct: 974 EFTANIARQEEKVRKKEKEILESREKQQREAL----------ERALARLERRHSALQRHS 1023
Query: 1070 EYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERK 1129
E + RQK AS ++ SR ++ + L L + + +
Sbjct: 1024 TLGMEIEEQRQK--LASLNSGSREQSGLQASLEAEQEA---------------LEKDQER 1066
Query: 1130 QQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDG 1189
+ +++K K+ E D + ++ L+ ++ ++ M ++ + E++
Sbjct: 1067 LEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEE- 1125
Query: 1190 EGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQL 1236
+ ++Q L + + TS D K ++L I+R+L
Sbjct: 1126 ---------VQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKL 1163
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 289 bits (740), Expect = 1e-77
Identities = 183/445 (41%), Positives = 257/445 (57%), Gaps = 23/445 (5%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRD-------RVFTFDFVFGKNSTQD 58
VKV VR RP+ +E Q V V Q I + FTFD + + +
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 59 EVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIF 118
++YN PLV + EGYN T+FAYGQTGSGK++T+ G Q+GIIPRA + +F
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQG---LPDPPSQRGIIPRAFEHVF 122
Query: 119 QSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVES 178
+S+ + F V+ SY+E+Y ED+RDLL +T K L ++E + + G V S
Sbjct: 123 ESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQK-LELKEHPEKGVYVKGLSMHTVHS 181
Query: 179 AGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVS 238
+ ++E G R G T MN+ SSRSH+IFTISI M A ++ R
Sbjct: 182 VAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISI-----EMSAVDERGKDHLR--AG 234
Query: 239 KFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKI 298
K + VDLAGSER +KTG TGER KE+ +IN L ALGNVISAL D R K H+PYRD+K+
Sbjct: 235 KLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK--HVPYRDSKL 292
Query: 299 TRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDE 358
TRLL+DSLGG+ KT+M+ C+SP+ +N+DE+L++L+YANRA+NIRNKP +N P+ + E
Sbjct: 293 TRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLRE 352
Query: 359 MEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHS--LEEQVAQLQGECLGYQCCVE 416
+ EIK L+ L Q + S + ++R+ PD ++ L + V Q E Q E
Sbjct: 353 YQEEIKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEA-EKQLIRE 411
Query: 417 EAFTFLVDLKDTVRLNEKQQHKLQE 441
E L LK + ++ + +L+E
Sbjct: 412 EYEERLARLKADYKAEQESRARLEE 436
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 289 bits (740), Expect = 1e-77
Identities = 183/445 (41%), Positives = 257/445 (57%), Gaps = 23/445 (5%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRD-------RVFTFDFVFGKNSTQD 58
VKV VR RP+ +E Q V V Q I + FTFD + + +
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 59 EVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIF 118
++YN PLV + EGYN T+FAYGQTGSGK++T+ G Q+GIIPRA + +F
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQG---LPDPPSQRGIIPRAFEHVF 122
Query: 119 QSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVES 178
+S+ + F V+ SY+E+Y ED+RDLL +T K L ++E + + G V S
Sbjct: 123 ESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQK-LELKEHPEKGVYVKGLSMHTVHS 181
Query: 179 AGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVS 238
+ ++E G R G T MN+ SSRSH+IFTISI M A ++ R
Sbjct: 182 VAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISI-----EMSAVDERGKDHLR--AG 234
Query: 239 KFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKI 298
K + VDLAGSER +KTG TGER KE+ +IN L ALGNVISAL D R K H+PYRD+K+
Sbjct: 235 KLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK--HVPYRDSKL 292
Query: 299 TRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDE 358
TRLL+DSLGG+ KT+M+ C+SP+ +N+DE+L++L+YANRA+NIRNKP +N P+ + E
Sbjct: 293 TRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLRE 352
Query: 359 MEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHS--LEEQVAQLQGECLGYQCCVE 416
+ EIK L+ L Q + S + ++R+ PD ++ L + V Q E Q E
Sbjct: 353 YQEEIKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVIQHDVEA-EKQLIRE 411
Query: 417 EAFTFLVDLKDTVRLNEKQQHKLQE 441
E L LK + ++ + +L+E
Sbjct: 412 EYEERLARLKADYKAEQESRARLEE 436
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 288 bits (737), Expect = 3e-77
Identities = 318/1346 (23%), Positives = 597/1346 (44%), Gaps = 191/1346 (14%)
Query: 2 EEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVI-IGRDRVFTFDFVFGKNSTQDEV 60
EE V V VR+RPL +E V ++ + + + F FD VF N T V
Sbjct: 3 EEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNV 62
Query: 61 YNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQS 120
Y P++ S I+GYN T+FAYGQT SGKTYT+ G E G+IPRAI +IFQ
Sbjct: 63 YEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGS------EDHLGVIPRAIHDIFQK 116
Query: 121 ISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAG 180
I + P +F ++VSY+E+Y E + DLL MK L IRED N + E V ++
Sbjct: 117 IKKFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSE 176
Query: 181 EVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKF 240
+ + G +RH G T+MN+ SSRSH IF + + K + +GS VS
Sbjct: 177 MALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVK-----VSHL 231
Query: 241 HFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITR 300
+ VDLAGSER +TG G R KE IN L LG VI L D + I YRD+K+TR
Sbjct: 232 NLVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSD-GQVGGFINYRDSKLTR 290
Query: 301 LLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEME 360
+L++SLGG+AKT +I ++P S FDE+L +L++A+ A+ ++N P VN + E
Sbjct: 291 ILQNSLGGNAKTRIICTITPVS--FDETLTALQFASTAKYMKNTPYVN------EVSTDE 342
Query: 361 FEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQG------ECLGYQCC 414
+K R+ + + + + + R + + +++ L E+ LQ E L
Sbjct: 343 ALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLV 402
Query: 415 VEEAFTFLVDLKD---------TVRLNEKQQHKLQEWF---------------NMIQEVR 450
+ T +LK ++N+ + + F N+++E+
Sbjct: 403 TSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREID 462
Query: 451 KAVLTSFRGIGGT----ASLEEGPQHVTVLQ--LKRELKKCQC-----VLAADEVVFNQK 499
++V + T + +E P + Q ++ EL + VL +++ ++
Sbjct: 463 ESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKE 522
Query: 500 ELEV----------------KELKNQVQMMVQENKGHAVSLKEAQKVNR-LQNEKIIEQQ 542
E+E+ K K+Q ++ E +K A+ N+ L+NE + +
Sbjct: 523 EMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVE 582
Query: 543 LLVDQLSEELTKLNLSVTSSAKENCGDGPDARI-----PERRPYTVPFDTHLGHYIYIPS 597
LL ++ +++ KL + S EN + P++ T+ FD + + +
Sbjct: 583 LLREK-EDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTL-FDAET---VALDA 637
Query: 598 RQD-----SRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESE 652
+++ S + M L + Q+ +E + K+ D E E
Sbjct: 638 KRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKM--------QVDLEKE 689
Query: 653 GQEKSGTRCRSRSWIQ---KPDSVCSLV---ELSDTQDETQKSDLENEDLKIDCLQESQE 706
Q + S I D +C+L +++D Q E K ENE L+ + + S+
Sbjct: 690 LQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSEL 749
Query: 707 LNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEH 766
+L ER+ E + K EL I K+ L E++ + + + ++ + K +
Sbjct: 750 KSLP--SEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEE----IGKTKD 803
Query: 767 DAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKK 826
D + T ++ Q + + D K K+ E ++M+ + V + ++ Q+
Sbjct: 804 DLATTQSNYKSTDQEFQNFKTLHM-DFEQKYKMVLEENERMN--QEIVNLSKEAQKFDSS 860
Query: 827 LASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRD--------QQ 878
L +L + + EL++ ++ +++ +L+E+ E R ++R+ QQ
Sbjct: 861 LGALKTELSYKTQELQEKTREVQ-ERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQ 919
Query: 879 KIKEIQLKTGQEEGLKPKAEDL------------DACNL-----KRRKGSFGSI-DHLQK 920
++E++ T +++ LK E L D N+ ++ + + S+ H +
Sbjct: 920 TLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQET 979
Query: 921 LDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQAL 980
++ K + EEV + L+ + E + + +++ + KK+ L +N + ++
Sbjct: 980 INTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDL-----EAKNTQTLTADVK 1034
Query: 981 NTDSLKISTRLNLLEQELSEKNVQLQTSTAEE---KTKISEQVEVLQKEKDQLQKRRHNV 1037
+ + ++ ++ L QE +E L++ AE+ KT + E +E+ + +++L R
Sbjct: 1035 DNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEEL---RLLG 1091
Query: 1038 DEKLKNGRVLSPEEEHV------LFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLS 1091
DE K +++ E+ H L + + + +E ++ +++ +Q +Q+ L
Sbjct: 1092 DELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL-------- 1143
Query: 1092 RGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVREL 1151
NV E+++ + + N++ NL+ + ++L E M+ + LE + ++L
Sbjct: 1144 ---LNVQEEMSEMQ---------KKINEIENLKNELKNKELTLEHMETERLE---LAQKL 1188
Query: 1152 ESALDHLKLQCDRRLTLQ--QKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKD 1209
+ +K R L+ QK E + L + +E + G+ +++++
Sbjct: 1189 NENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQT-----KEELKIAHIH 1243
Query: 1210 LYFYKKTSRDHKKKLKELVGEAIRRQ 1235
L +++T + ++ + E + I Q
Sbjct: 1244 LKEHQETIDELRRSVSEKTAQIINTQ 1269
Score = 112 bits (281), Expect = 2e-24
Identities = 190/954 (19%), Positives = 384/954 (40%), Gaps = 122/954 (12%)
Query: 326 DESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINR 385
DE + + +N K S DR+ E+E ++K + LQ +Q Q +
Sbjct: 1092 DELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQ---QQLLNVQE 1148
Query: 386 EGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNM 445
E S +I+ +E L+ E + +E T ++L + N ++ + + +
Sbjct: 1149 EMSEMQKKINEIE----NLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKV 1204
Query: 446 IQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRELKKCQCVLAADEVVFNQKELEVKE 505
++E++K+ T + G E T LQ K ELK L + ++ V E
Sbjct: 1205 LKELQKSFETERDHLRGYIREIE----ATGLQTKEELKIAHIHLKEHQETIDELRRSVSE 1260
Query: 506 LKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKE 565
Q+ K H +E ++ + ++++ V + E + +L L S +
Sbjct: 1261 KTAQIINTQDLEKSHTKLQEEIPVLH--EEQELLPNVKEVSETQETMNELELLTEQSTTK 1318
Query: 566 NCGDGPDARIP-ERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRS 624
+ ARI ER F + +D+ K I +
Sbjct: 1319 D--STTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKT-----------IKEALEVKH 1365
Query: 625 QMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQ--KP-DSVCSLVE--- 678
L HI E + Q S + ++ +EK + S ++ KP DS +E
Sbjct: 1366 DQLKEHIRE--TLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEM 1423
Query: 679 ------LSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTIN 732
L ++ DE + E +DL+ LQE + +LK + + E K E
Sbjct: 1424 LGLSKRLQESHDEMKSVAKEKDDLQ--RLQEVLQSESDQLKEN---IKEIVAKHLETEEE 1478
Query: 733 IKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELEN----K 788
+K+ +KE +T N+ + + +++ ++ E +L +++ E E K
Sbjct: 1479 LKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIK 1538
Query: 789 DLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQ-------QDSKKLASLSIQNEKRANEL 841
+S+V KV K+F++ A +Q ++ K Q+S++ + I+ ++ +
Sbjct: 1539 QISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRV 1598
Query: 842 EQSV----DHMKYQKIQLQRKLREENEKRKQL--DAVIKRDQQKIKEIQLKTGQEEGLKP 895
++++ D +K ++ K++E EK Q + Q+K+ EI+ Q E K
Sbjct: 1599 QEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKL 1658
Query: 896 KAEDLDACNLK----------------RRKGSFGSIDHLQKL--DEQKKWLDEEVEKVLN 937
E+++ N++ + + S++ K+ D+ K+ L E + + L
Sbjct: 1659 NLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLE 1718
Query: 938 QRQELEELEADLKKREAIVSKKEALLQEK----SHLENKKLRSSQALNTDSLKISTRLNL 993
+++EL+ + LK+ + + K ++ EK S+++ S+ AL LKI L +
Sbjct: 1719 KQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRI 1778
Query: 994 LEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEH 1053
L E+ Q + + + +SE+ + L + L+ + EK++ + EH
Sbjct: 1779 AHMHLKEQ----QETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKA----NEH 1830
Query: 1054 VLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTIL 1113
L L++ + + + E ++ + K + L N+ +KL + E+++++
Sbjct: 1831 QLITLKKDVNETQKKVS-EMEQLKKQIKDQSLTLSKLEIENLNLAQKLH-ENLEEMKSVM 1888
Query: 1114 FRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEH 1173
+ NLR E +L +++K + E E++ L + + KEH
Sbjct: 1889 ----KERDNLRRVEETLKLERDQLKESLQETKARDLEIQQEL--------KTARMLSKEH 1936
Query: 1174 EQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKLKEL 1227
++ + L E KT + I ++KDL K+ + +KK++EL
Sbjct: 1937 KETVDKLREKISE----------KTIQ--ISDIQKDL---DKSKDELQKKIQEL 1975
Score = 97.8 bits (242), Expect = 6e-20
Identities = 194/1014 (19%), Positives = 420/1014 (41%), Gaps = 149/1014 (14%)
Query: 323 SNFDESLNSLKYANRARNIRNKPTVNFSPESDRID--EMEFEIKLLREALQSQQAGVSQT 380
SN ++L+ +++ N A + N+ + S R D + + + LR + + + +
Sbjct: 473 SNTLDTLSEIEW-NPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEK 531
Query: 381 TQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLK-------DTVRLNE 433
++ + + + ++Q QL E + V+ A + DL+ + +R E
Sbjct: 532 NDLDEFEALERK---TKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKE 588
Query: 434 KQQHKLQEWFNM--IQEVRKAVLTSFRGIGGTASLEEG--PQHVTVLQLKRELKKCQCVL 489
Q KLQE+ + ++ ++ + S I +++ L KRE L
Sbjct: 589 DQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRE----SAFL 644
Query: 490 AADEVVFNQKELEV----KELKNQVQ-----------MMVQENKGHAVSLKEAQKVNRLQ 534
++ + +K E+ K+++N +Q M V K + E K+ L
Sbjct: 645 RSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLI 704
Query: 535 NEKIIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIY 594
+ K+ + L +L ++T L + +EN + + ++P +
Sbjct: 705 DGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELK-SLPSEVERLRK-E 762
Query: 595 IPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEE----QDKVLHCQFSDNSDDEE 650
I + + + TS D++F+ + + G +EE +D + Q + S D+E
Sbjct: 763 IQDKSEELHIITSEK----DKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQE 818
Query: 651 SEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELN-- 708
+ + + + ++ E+ + E QK D LK + ++QEL
Sbjct: 819 FQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEK 878
Query: 709 --------------LQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVS 754
++L+N + L +++ +T ++ + +K L + +D K +
Sbjct: 879 TREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQ 938
Query: 755 KQYSLKVTKLEHDAEQAKVELIETQKQLQE--------------LENKDLSDVAMKVKLQ 800
+ ++ +L+ D I+TQ+QL+ L++K +V+ + ++
Sbjct: 939 ESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHME 998
Query: 801 KEFRKKMDAAKLRVQVLQKKQQ-DSKKLASLS--------IQNEKRA-------NELEQS 844
+ + D + ++ + KKQ ++K +L+ I+ +++ NEL+Q
Sbjct: 999 ENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQM 1058
Query: 845 VDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACN 904
++ + +K QL+ L+E E + ++ ++K+ Q QE+ K E
Sbjct: 1059 LESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEG----E 1114
Query: 905 LKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQ 964
L R ++ +KL E+ + L E+ +++LN ++E+ E++ + + E +
Sbjct: 1115 LSRTCDRLAEVE--EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENL--------- 1163
Query: 965 EKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQ 1024
K+ L+NK+L + + + T+ L+++ +LN +N + S +E+ + E + +
Sbjct: 1164 -KNELKNKEL-TLEHMETERLELAQKLN--------ENYEEVKSITKERKVLKELQKSFE 1213
Query: 1025 KEKDQLQKRRHNVD-------EKLKNGRVLSPEEEHVLFQLEEGIEALEAAI------EY 1071
E+D L+ ++ E+LK + E + + +L + A I E
Sbjct: 1214 TERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEK 1273
Query: 1072 RNESIQ------NRQKSLRASFHNLSRGE--ANVLEKLACLSPVEIRTILFRYFNKVVNL 1123
+ +Q + ++ L + +S + N LE L S + T L R + + L
Sbjct: 1274 SHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRL 1333
Query: 1124 REAERKQQLYNEEMKMKVLERDNMVRELESALD--HLKLQCDRRLTLQQKEHEQKMQLLL 1181
E ++ Q EE+K ERDN+ + ++ AL+ H +L+ R TL + + Q Q
Sbjct: 1334 NEKFQESQ---EEIKSLTKERDNL-KTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQS 1389
Query: 1182 HHFKEQDGE-----GIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKLKELVGE 1230
+ KE+D E ME FK + + ++E ++ K ++ ++K + E
Sbjct: 1390 LNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKE 1443
Score = 97.1 bits (240), Expect = 1e-19
Identities = 165/816 (20%), Positives = 356/816 (43%), Gaps = 103/816 (12%)
Query: 433 EKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRELK--KCQCVLA 490
EK KLQE ++ E ++ + + E + + L+L E K LA
Sbjct: 1272 EKSHTKLQEEIPVLHEEQEL-------LPNVKEVSETQETMNELELLTEQSTTKDSTTLA 1324
Query: 491 ADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSE 550
E+ + + +E + +++ + +E + + ++KEA +V Q ++ I + L ++ E
Sbjct: 1325 RIEMERLRLNEKFQESQEEIKSLTKE-RDNLKTIKEALEVKHDQLKEHIRETLA--KIQE 1381
Query: 551 ELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHL--------GHYIYIPSRQDSR 602
+K S+ K+N +I P D+ L G + D
Sbjct: 1382 SQSKQEQSLNMKEKDN----ETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEM 1437
Query: 603 KVHTSPPMYSLDRIFAGFRTRSQMLLGHI----------EEQDKVLHCQFSDNSDDEESE 652
K + L R+ ++ S L +I EE+ KV HC + ++ +E
Sbjct: 1438 K-SVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQ-EETINE 1495
Query: 653 GQEKSGTRCRSRSWIQKPDSVCSLVELSDT-QDETQKSDLENEDLKIDCLQESQEL--NL 709
+ + S IQK L ++D Q++ Q+ + E I + E QE L
Sbjct: 1496 LRVNLSEKETEISTIQK-----QLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNEL 1550
Query: 710 QKLKNSERILTEAKQ----KMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLE 765
++ K + A Q KM ELT ++ ++ I+ +IK + K V + ++ +L+
Sbjct: 1551 KQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLK 1610
Query: 766 HDAEQAKVELIETQ-KQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDS 824
+ ++ ++ E+Q K+ Q L+ +++ K+ + +++ + KL ++ ++ +
Sbjct: 1611 ENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRL 1670
Query: 825 KKLASLSIQN----EKRANELEQSVDHMKYQKIQLQRKLRE----ENEKRKQLDAV---I 873
++ +++ K ++L + +K ++ QL+ LRE + EK+++L V +
Sbjct: 1671 TQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHL 1730
Query: 874 KRDQQKIKE----IQLKTGQ----EEGLKPKAEDLDACNLKRRKGSFGSIDHLQK----L 921
K Q+ I + + KT + ++ L+ + L A +LK ++ + HL++ +
Sbjct: 1731 KEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETI 1790
Query: 922 DEQKKWLDEEVEKVLNQRQELEELEADLKKR---------EAIVSKKEALLQEKSHLENK 972
D+ + + E+ +K+ N +++LE A L+++ + I KK+ +K E +
Sbjct: 1791 DKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEME 1850
Query: 973 KLR---SSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQ 1029
+L+ Q+L L+I LN L Q+L E N++ S +E+ + E L+ E+DQ
Sbjct: 1851 QLKKQIKDQSLTLSKLEIE-NLN-LAQKLHE-NLEEMKSVMKERDNLRRVEETLKLERDQ 1907
Query: 1030 LQK-------RRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKS 1082
L++ R + ++LK R+LS E + + +L E I I + + +
Sbjct: 1908 LKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDE 1967
Query: 1083 LRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVL 1142
L+ L + E +L ++ + K+ + + +++ + N M+ +
Sbjct: 1968 LQKKIQELQKKELQLL---------RVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRM 2018
Query: 1143 ERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQ 1178
+ + ++L +L+ +++ R L++ + KM+
Sbjct: 2019 DNFQLTKKLHESLEEIRIVAKERDELRRIKESLKME 2054
Score = 84.0 bits (206), Expect = 1e-15
Identities = 142/597 (23%), Positives = 246/597 (41%), Gaps = 79/597 (13%)
Query: 684 DETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLI--K 741
DE+ S+ + +D L E + KL N E I +E + + E L K
Sbjct: 462 DESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEK 521
Query: 742 ELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQL---QELENKDL-SDVAMKV 797
E ++ K+ ++ K + D E + I K L E+ N+DL ++++ KV
Sbjct: 522 EEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKV 581
Query: 798 KLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQR 857
+L +E K+ KL+ + +K ++ K S S+++ + +++Q++ + + +R
Sbjct: 582 ELLRE--KEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKR 639
Query: 858 K---LREEN----EKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKG 910
+ LR EN EK K+L K Q +IQL Q E K DL+ K +
Sbjct: 640 ESAFLRSENLELKEKMKELATTYK---QMENDIQLYQSQLEAKKKMQVDLE----KELQS 692
Query: 911 SFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLE 970
+F I L L +D +V K L ELE DL+K K E
Sbjct: 693 AFNEITKLTSL------IDGKVPKDLLCNLELEGKITDLQKE-----------LNKEVEE 735
Query: 971 NKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQV---------- 1020
N+ LR L ++ + + + L +E+ +K+ +L T+E+ SE V
Sbjct: 736 NEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLL 795
Query: 1021 EVLQKEKDQL---QKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQ 1077
E + K KD L Q + D++ +N + L + E + E E + I ++ Q
Sbjct: 796 EEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQ 855
Query: 1078 NRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEM 1137
SL A LS + EK R + +N E + K+QL N +
Sbjct: 856 KFDSSLGALKTELSYKTQELQEKT-------------REVQERLNEME-QLKEQLENRDS 901
Query: 1138 KMKVLERDN--MVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMET 1195
++ +ER+ + +L+ L+ +K Q+K+ +++Q L ++Q I +T
Sbjct: 902 TLQTVEREKTLITEKLQQTLEEVK------TLTQEKDDLKQLQESLQIERDQLKSDIHDT 955
Query: 1196 FKTYEDKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLKPE 1252
D +QL L K+ ++ LK + E + R L + E G K E
Sbjct: 956 VNMNIDTQEQLRNALESLKQ-HQETINTLKSKISEEVSRNL----HMEENTGETKDE 1007
Score = 73.6 bits (179), Expect = 1e-12
Identities = 171/858 (19%), Positives = 355/858 (41%), Gaps = 162/858 (18%)
Query: 318 VSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFEI----KLLREALQSQ 373
+ S S ++SLN + N I ++ F P+ + +E E+ K L+E+
Sbjct: 1379 IQESQSKQEQSLNMKEKDNETTKIVSEME-QFKPKDSALLRIEIEMLGLSKRLQESHDEM 1437
Query: 374 QAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQ-------CCVEEAFTFLVDL- 425
++ + + R + L+E + ++ + L + CC++E + +L
Sbjct: 1438 KSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELR 1497
Query: 426 --------------KDTVRLNEKQQHKLQE------WFNMIQ---------------EVR 450
K +N+K Q+K+QE FN+ Q E R
Sbjct: 1498 VNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHR 1557
Query: 451 KAVLTSFRGIGG-----TASLEEGPQHVTVL-QLKRELKKCQCVLAAD---------EVV 495
KA ++ + I T L+E + + ++ + K E+K+ Q L + E+V
Sbjct: 1558 KAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIV 1617
Query: 496 FNQKELEVKE---LKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEEL 552
KE + KE LK QE LKE + +L E I + + + Q+ E
Sbjct: 1618 AKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHEN 1677
Query: 553 TKLNLSVTS------SAKENCGDGPDARIPERRPYTVPFDTHLGH-----YIYIPSRQD- 600
+ SVT S +E D ++ E T+ D ++++ Q+
Sbjct: 1678 LEEMRSVTKERDDLRSVEETLKVERD-QLKENLRETITRDLEKQEELKIVHMHLKEHQET 1736
Query: 601 --------SRKVHTSPPM-----YSLDRIFA-GFRTRSQMLLGHI---EEQDKV--LHCQ 641
S K + M +S D + A + + ++ + H+ E+Q+ + L
Sbjct: 1737 IDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGI 1796
Query: 642 FSDNSDDEESEGQEKSGTRCRSRSWIQK-PDSVCSLVELSDTQDETQKSDLENEDLKIDC 700
S+ +D + ++ + + + IQ+ + L+ L +ETQK E E LK
Sbjct: 1797 VSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQI 1856
Query: 701 LQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDL--IKELIKTGNDAKSVSKQYS 758
+S LT +K ++ L + K+ E+L +K ++K ++ + V +
Sbjct: 1857 KDQS--------------LTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLK 1902
Query: 759 LKVTKLEHDAEQAKVELIETQKQLQEL-----ENKD--------LSDVAMKVK-LQKEFR 804
L+ +L+ ++ K +E Q++L+ E+K+ +S+ +++ +QK+
Sbjct: 1903 LERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLD 1962
Query: 805 KKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQ----------SVDHMKYQKIQ 854
K D + ++Q LQKK+ ++ + K+ NE+EQ S+ ++ Q
Sbjct: 1963 KSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQ 2022
Query: 855 LQRKLREENEKRKQLDAVIKRDQQKIKEIQ--LKTGQEEGLKPKAEDL--DACNLKRRKG 910
L +KL E E+ + ++ +++ +++ I+ LK +++ + E + D N + +
Sbjct: 2023 LTKKLHESLEEIR----IVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPE 2078
Query: 911 SFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEE-------LEADLKKREAIVSKKEALL 963
D Q L E + ++++L + E+++ L DL+K I +KE +
Sbjct: 2079 KRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKE--IEFQKELSM 2136
Query: 964 QEKSHLENKKLRSS--QALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKIS---- 1017
+ K++L L++ + L T + + S + + ++L + E+ I+
Sbjct: 2137 RVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEM 2196
Query: 1018 EQVEVLQKEKDQLQKRRH 1035
+ ++ ++K+K+ L K +H
Sbjct: 2197 DFIDEVEKQKELLIKIQH 2214
Score = 57.4 bits (137), Expect = 1e-07
Identities = 112/581 (19%), Positives = 259/581 (44%), Gaps = 58/581 (9%)
Query: 757 YSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQV 816
Y +V+ E ++ + E+++ +KQL+E+ + + K +L + +K K++ +
Sbjct: 334 YVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEK 393
Query: 817 LQKKQQDSKKLASLSIQNEKRANELEQ------SVDHMKYQKIQLQRKLREE-NEKRKQL 869
++ + +SL++Q E +A + ++ MK Q + K +L
Sbjct: 394 IENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKL 453
Query: 870 DAVIKRD-------QQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSF-GSIDHLQKL 921
+ R+ + + L T E P + L+ N++ S D+L
Sbjct: 454 SINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLD 513
Query: 922 DEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALN 981
EQ + EE+E L ++ +L+E EA +R+ ++ L+ E S+L+N ++ ++ N
Sbjct: 514 YEQLRTEKEEMELKLKEKNDLDEFEA--LERKTKKDQEMQLIHEISNLKN-LVKHAEVYN 570
Query: 982 TD-SLKISTRLNLLEQELSE-------------KNVQLQTSTAEEKTKISEQVE--VLQK 1025
D ++S+++ LL ++ + +N+++ S + E + +Q++ +
Sbjct: 571 QDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDA 630
Query: 1026 EKDQLQKRRHNVDEKLKNGRVLSPEEE--HVLFQLEEGIEALEAAIEYRNESIQNRQKSL 1083
E L +R + + +N + +E Q+E I+ ++ +E + + + +K L
Sbjct: 631 ETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKEL 690
Query: 1084 RASFHNLSR----GEANVLEKLACLSPVEIR-TILFRYFNKVVNLREAERKQQLYNEEMK 1138
+++F+ +++ + V + L C +E + T L + NK V EA R++ + E+K
Sbjct: 691 QSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELK 750
Query: 1139 MKVLERDNMVRELESALDHLKLQCDR--RLTLQQKEHEQKMQLLLHHFKEQDGEGIMETF 1196
E + + +E++ + L + +L + E ++Q LL E+ G+ +
Sbjct: 751 SLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLL----EEIGK-TKDDL 805
Query: 1197 KTYEDKIQQLEKDLYFYKKTSRDHKKKLK------ELVGEAIRRQLAPSEYQEAGDGVLK 1250
T + + +++ +K D ++K K E + + I ++ ++ G LK
Sbjct: 806 ATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALK 865
Query: 1251 PEGGGMLSEELKWASRPESMKLSGRER---EMDSSASSLRT 1288
E ++EL+ +R +L+ E+ ++++ S+L+T
Sbjct: 866 TE-LSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQT 905
Score = 42.7 bits (99), Expect = 0.002
Identities = 69/299 (23%), Positives = 131/299 (43%), Gaps = 51/299 (17%)
Query: 648 DEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQ-- 705
+E +E +E+S T S+ W Q S+ E +T K+ L + Q+++
Sbjct: 2312 NESTEFEERSATI--SKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNP 2369
Query: 706 -------ELNLQKLKNSERILTEAKQK-MRELTINIKMKEDL-IKELIKTGNDAKSVSKQ 756
+L +K++ E L EAK+ M + + IKM+++L + I AK
Sbjct: 2370 HVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESN 2429
Query: 757 YSLKVTKLEHDAEQAKVELIET--QKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRV 814
L+ TK Q KV L ++++++L+ K + K+K KEF K++ A K V
Sbjct: 2430 KCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATV 2489
Query: 815 QVLQKKQQDSKKLASLSIQNEKRANELEQSVDH--------------------------M 848
+ Q++ +L +++ ++A + +H +
Sbjct: 2490 EY----QKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALIL 2545
Query: 849 KYQKIQLQR---KLREENEKR-KQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDAC 903
K + I+L++ KL+++NE+ KQ + ++ +Q E+ KT +E LK +A C
Sbjct: 2546 KSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEV--KTWKERTLKREAHKQVTC 2602
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 287 bits (735), Expect = 4e-77
Identities = 208/587 (35%), Positives = 316/587 (53%), Gaps = 56/587 (9%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDR--------VFTFDFVFGKNSTQ 57
V+V VR RP+ KE ++ V V QV + + FTFD V+ N+ Q
Sbjct: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
Query: 58 DEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEG---QKGIIPRAI 114
E+Y+ +PLV S+++G+N T+FAYGQTG+GKTYT+ G + G ++G+IP +
Sbjct: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEG------IRGDPEKRGVIPNSF 123
Query: 115 QEIFQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKEC 174
IF IS + + V+ SY+E+Y+E++RDLL + + K L ++E +
Sbjct: 124 DHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQT-KRLELKERPDTGVYVKDLSSF 182
Query: 175 HVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPR 234
+S E+ ++ +GN R G T MNEHSSRSHAIF I+I + E DG
Sbjct: 183 VTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITI----ECSEVGLDGE----N 234
Query: 235 HI-VSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPY 293
HI V K + VDLAGSER KTG GER KE+ +IN L ALGNVISAL D KS+HIPY
Sbjct: 235 HIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDG--KSTHIPY 292
Query: 294 RDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPES 353
RD+K+TRLL+DSLGG+AKTVM+ V P+S N +E+L +L+YANRA+NI+NKP VN P+
Sbjct: 293 RDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKD 352
Query: 354 DRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQC 413
+ E + EI L+ L+ + G + + REG EE+ + + E
Sbjct: 353 ALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDD 412
Query: 414 CVEEAFTFL-----VDLKDTVRLNEKQQHKLQEWFNMIQEVRK------------AVLTS 456
E L ++D + E++ L+E ++++R+ + S
Sbjct: 413 YWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMES 472
Query: 457 FRGIGGTASLEEGPQHVTVLQLKR----ELKKCQCVLAADEVVFNQKELEVKE----LKN 508
+GG ++ + +L+ KR E K+ + + +++ LE+KE L+
Sbjct: 473 KLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQ 532
Query: 509 QVQMMVQENKGHAVSLKEAQ-KVNRLQNEKIIEQQLLVDQLSEELTK 554
+V + ++ K L+ + +++ LQ E I E+Q L +Q ELT+
Sbjct: 533 EVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQEL-EQTQNELTR 578
Score = 48.9 bits (115), Expect = 3e-05
Identities = 81/397 (20%), Positives = 177/397 (44%), Gaps = 74/397 (18%)
Query: 706 ELNLQKLKNSERILTEAKQ--KMRELTINIKMKEDLIKELIKTGNDAKSVSKQY-SLKVT 762
+LNL L SER Q +++E T I + + +I D KS Y K+T
Sbjct: 240 KLNLVDLAGSERQAKTGAQGERLKEAT-KINLSLSALGNVISALVDGKSTHIPYRDSKLT 298
Query: 763 KLEHDA--EQAKVELI-----------ETQKQLQ------ELENKDLSDVAMKVKLQKEF 803
+L D+ AK ++ ET L+ ++NK + K L +EF
Sbjct: 299 RLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREF 358
Query: 804 RKKMDAAKLRVQ---VLQKKQQDSKKLASLS----IQNEKRANELEQSVDHM------KY 850
++++ K +++ + ++K+++ ++ S + E+ E E+ D +
Sbjct: 359 QEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQ 418
Query: 851 QKIQLQRKLREENEK--RKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRR 908
+K++++++ E+ ++ ++K ++K+++++ + E L K + +++ K
Sbjct: 419 EKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMES---KLL 475
Query: 909 KGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKR-EAIVSKKEAL--LQE 965
G +DH +EQ+K L+++ +++ Q++ E++ ++ R E + KE LQ+
Sbjct: 476 VGGKNIVDHT---NEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQ 532
Query: 966 KSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQK 1025
+ ++ KKL+ K+ ++L ++ E+ + EE K +++E Q
Sbjct: 533 EVDIKTKKLK----------KLFSKLQAVKAEIHD--------LQEEHIKERQELEQTQN 574
Query: 1026 EKDQLQKRRHNVDE---------KLKNGRVLSPEEEH 1053
E + K +H + E K+ N EE+H
Sbjct: 575 ELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDH 611
Score = 39.3 bits (90), Expect = 0.027
Identities = 42/211 (19%), Positives = 100/211 (47%), Gaps = 27/211 (12%)
Query: 681 DTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTE-----AKQKMRELTINIKM 735
+ ++E ++ + E +D K D +E QE KL+ +R + E A++KMR L K
Sbjct: 395 EEEEEGEEGEEEGDD-KDDYWREQQE----KLEIEKRAIVEDHSLVAEEKMRLLKEKEKK 449
Query: 736 KEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAM 795
EDL +E K ++ K+ +E +++ + Q++ + ++A
Sbjct: 450 MEDLRRE--------KDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAE 501
Query: 796 KVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQL 855
+ + ++E +++M++ + L+ K+ S + I+ +K L++ ++ K ++
Sbjct: 502 QKRREREIQQQMESRD--EETLELKETYSSLQQEVDIKTKK----LKKLFSKLQAVKAEI 555
Query: 856 QRKLREENEKRKQLDAVIKRDQQKIKEIQLK 886
E ++R++L+ + + +E++LK
Sbjct: 556 HDLQEEHIKERQELE---QTQNELTRELKLK 583
Score = 35.8 bits (81), Expect = 0.30
Identities = 38/184 (20%), Positives = 79/184 (42%), Gaps = 20/184 (10%)
Query: 627 LLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDET 686
++ H EQ K+L + + ++ + E + + R ++ ++ SL + D + +
Sbjct: 481 IVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKK 540
Query: 687 QK---SDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKEL 743
K S L+ +I LQE Q+L+ Q ELT +K+K +I+
Sbjct: 541 LKKLFSKLQAVKAEIHDLQEEHIKERQELE----------QTQNELTRELKLKHLIIENF 590
Query: 744 IKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEF 803
I +K +++ + + + + K+ I T+ + Q++ + +S V K L +
Sbjct: 591 IPLEEKSKIMNRAF------FDEEEDHWKLHPI-TRLENQQMMKRPVSAVGYKRPLSQHA 643
Query: 804 RKKM 807
R M
Sbjct: 644 RMSM 647
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 282 bits (722), Expect = 1e-75
Identities = 260/961 (27%), Positives = 459/961 (47%), Gaps = 99/961 (10%)
Query: 3 EIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYN 62
E +KV R RPL E L + + + V+IG+ + + FD V N+TQ++VYN
Sbjct: 6 ECSIKVMCRFRPLNEAEILRGDKFIPK-FKGDETVVIGQGKPYVFDRVLPPNTTQEQVYN 64
Query: 63 TCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGG-HIASVVEGQKGIIPRAIQEIFQSI 121
C K +V ++EGYN T+FAYGQT SGKT+T+ G H ++ GIIPR +IF I
Sbjct: 65 ACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM----GIIPRIAHDIFDHI 120
Query: 122 -SEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAG 180
S +++F++KVSY E+Y + +RDLL++ S +L + ED+ + G E V S
Sbjct: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLAVHEDKNRVPYVKGCTERFVSSPE 178
Query: 181 EVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKF 240
EVM +++ G A RH T MNEHSSRSH+IF I+I Q +N+E + + + K
Sbjct: 179 EVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQ--ENVE--------TEKKLSGKL 228
Query: 241 HFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITR 300
+ VDLAGSE+V+KTG G E+ IN L ALGNVISAL + + +H+PYRD+K+TR
Sbjct: 229 YLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK--THVPYRDSKMTR 286
Query: 301 LLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVN-----------F 349
+L+DSLGG+ +T ++ C SPS N E+ ++L + RA+ I+N +VN +
Sbjct: 287 ILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKY 346
Query: 350 SPESDR-------IDEMEFEIKLLR--EALQSQQAGVSQTTQINREGSPDTNRIHSLEEQ 400
E ++ I +E E+ R EA+ + +S Q N E +T I ++
Sbjct: 347 EKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQ-ISAKDQKNLEPCDNTPIIDNIAPV 405
Query: 401 VAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGI 460
VA + EE + ++ R + + ++ + + +++++ +L +
Sbjct: 406 VAGIS---------TEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELL 456
Query: 461 GGT-ASLEEGPQHVTVLQLKRELKKCQC--VLAADE---VVFNQKELEVKELKNQVQMMV 514
T E+ + +T LQ++ E K + VL A E V ++QK EV++ + +
Sbjct: 457 ASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLT 516
Query: 515 QENKGHAVSL----KEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKENCGDG 570
E +L +E ++ L N + +++ L ++L ++ + ++ + D
Sbjct: 517 DELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADV 576
Query: 571 P---DARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQML 627
+ R Y + + + + +S ++ ++ M + +R A Q+L
Sbjct: 577 NGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAA----CQLL 632
Query: 628 LGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDE-- 685
+ E + K L + N + + + +E + + ++ + + V D + E
Sbjct: 633 ISQHEAKIKSL-TDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHE-VSFQDKEKEHL 690
Query: 686 TQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIK 745
T+ D E ++ ES QK + R E KQK+ + ++ K L +E +
Sbjct: 691 TRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLS 750
Query: 746 TG-NDAKSVSKQYSLKVTK---LEHDAEQAKVEL----------IETQKQLQELENKDLS 791
+ N K ++ +K+ K L EQA+ +L ++T L++L +DL+
Sbjct: 751 SDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLT 810
Query: 792 D-VAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKY 850
V V+L + A K ++ L+ + Q K +L + ++
Sbjct: 811 TRVKKSVELDNDDGGGSAAQKQKISFLENNLE----------QLTKVHKQLVRDNADLRC 860
Query: 851 QKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKG 910
+ +L+++LR E+ K L++ +K ++ + + QE + E + A N+ RR
Sbjct: 861 ELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQE--VDRIKEAVRAKNMARRAH 918
Query: 911 S 911
S
Sbjct: 919 S 919
Score = 63.2 bits (152), Expect = 2e-09
Identities = 94/442 (21%), Positives = 200/442 (45%), Gaps = 58/442 (13%)
Query: 677 VELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQK----------- 725
+E +DE ++ E+L ++ Q+SQE+ K + +E++ E QK
Sbjct: 475 IENEAAKDEVKEVLQALEELAVNYDQKSQEVE-DKTRANEQLTDELAQKTTTLTTTQREL 533
Query: 726 --MRELTINIKMKED-----LIKELIKTG-----NDAKSVSKQYSLKVTKLEHDAEQAKV 773
++EL+ + K + L+K+L + G ND K+++ + +E + A++
Sbjct: 534 SQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGV----IEEEFTMARL 589
Query: 774 ELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKK-QQDSKKLASLS- 831
+ + + +++ L N+ Q + +KM+A++ + Q Q K+ SL+
Sbjct: 590 YISKMKSEVKSLVNRS----KQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTD 645
Query: 832 -IQN-EKRANELEQSVDHMKYQ--KIQLQRKLREENEKRKQLDAVIK----RDQQKIKEI 883
+QN E++ +LE+S D + + K++ Q K+ E + + K+ + + + + +K E
Sbjct: 646 YMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ 705
Query: 884 QLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQ-EL 942
Q+++ +E K + D K++ ID ++ L+++ + E++ N+ + E
Sbjct: 706 QMESHREAHQKQLSRLRDEIEEKQK-----IIDEIRDLNQKLQLEQEKLSSDYNKLKIED 760
Query: 943 EELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELS--- 999
+E E L+K + K+E ++ LE R Q L+ L Q+L+
Sbjct: 761 QEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHN-------LRKLFVQDLTTRV 813
Query: 1000 EKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLE 1059
+K+V+L +++ L+ +QL K + + R P+ E L
Sbjct: 814 KKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATA 873
Query: 1060 EGIEALEAAIEYRNESIQNRQK 1081
E ++ALE+A++ E+ +K
Sbjct: 874 ERVKALESALKEAKENAMRDRK 895
Score = 62.0 bits (149), Expect = 4e-09
Identities = 114/531 (21%), Positives = 231/531 (43%), Gaps = 80/531 (15%)
Query: 741 KELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQ 800
K + G AK++ S+ LE AE+ K + E +K+ +NK L +V ++++
Sbjct: 315 KSTLMFGQRAKTIKNTVSVN---LELTAEEWKKKY-EKEKE----KNKTLKNVIQHLEME 366
Query: 801 KEFRKKMDAAKLRVQVLQKKQQDSKK-------------LASLSIQNEKRANELEQSV-- 845
+ +A Q+ K Q++ + +A +S + +++ +E S+
Sbjct: 367 LNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYR 426
Query: 846 -----DHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDL 900
D Q+ QL KL+++ + +L A +RD +KI+E +L Q E K E
Sbjct: 427 QLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQE-ELTRLQIENEAAKDEVK 485
Query: 901 DACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKE 960
+ LQ L+E D++ ++V ++ + E+L +L ++ ++ +
Sbjct: 486 EV---------------LQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQ 530
Query: 961 ALLQEKSHLEN-KKLRSSQALN--------------TDSLKISTRLN-LLEQELSEKNVQ 1004
L + L N +K R+++ LN T+ +K +N ++E+E + +
Sbjct: 531 RELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLY 590
Query: 1005 LQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHV--LFQLEEGI 1062
+ +E K+ ++ ++ + D +K + E ++S E + L + +
Sbjct: 591 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM 650
Query: 1063 EALEAAIEYRNESIQNRQKSLRA--SFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKV 1120
E +E +S+ LRA H +S + E++ L + ++
Sbjct: 651 EQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ---QM 707
Query: 1121 VNLREAERKQ--QLYNE-EMKMKVLERDNMVRELES--ALDHLKLQCD-RRLTLQQKEHE 1174
+ REA +KQ +L +E E K K+++ +R+L L+ KL D +L ++ +E E
Sbjct: 708 ESHREAHQKQLSRLRDEIEEKQKIIDE---IRDLNQKLQLEQEKLSSDYNKLKIEDQERE 764
Query: 1175 QKMQ--LLLHHFKEQDGEGIMETFKTYEDKIQQLE--KDLYFYKKTSRDHK 1221
K++ LLL+ +EQ E + +T ++Q L + L+ T+R K
Sbjct: 765 MKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKK 815
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 282 bits (722), Expect = 1e-75
Identities = 254/939 (27%), Positives = 454/939 (48%), Gaps = 100/939 (10%)
Query: 3 EIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYN 62
E +KV R RPL E L + + + V+IG + + FD VF N+TQ++VY+
Sbjct: 7 ECSIKVLCRFRPLNQAEILRGDKF-IPIFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYH 64
Query: 63 TCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGG-HIASVVEGQKGIIPRAIQEIFQSI 121
C +V ++ GYN T+FAYGQT SGKT+T+ G H ++ GIIPR ++IF I
Sbjct: 65 ACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM----GIIPRIARDIFNHI 120
Query: 122 -SEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAG 180
S +++F++KVSY E+Y + +RDLL++ + +L + ED+ + G E V S
Sbjct: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVTKT--NLSVHEDKNRVPFVKGCTERFVSSPE 178
Query: 181 EVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKF 240
E++ +++ G + RH T MNEHSSRSH+IF I+I Q +NME + S K
Sbjct: 179 EILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQ--ENMETEQKLS--------GKL 228
Query: 241 HFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITR 300
+ VDLAGSE+V+KTG G E+ IN L ALGNVISAL + + S++PYRD+K+TR
Sbjct: 229 YLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK--SYVPYRDSKMTR 286
Query: 301 LLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESD----RI 356
+L+DSLGG+ +T M C SPSS N E+ ++L + RA+ I+N +VN ++ +
Sbjct: 287 ILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKY 346
Query: 357 DEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLE--------EQVAQLQGEC 408
++ + + K +E + +A +S+ N E P+T R+ E E+
Sbjct: 347 EKEKEKTKAQKETIAKLEAELSRWR--NGENVPETERLAGEEAALGAELCEETPVNDNSS 404
Query: 409 LGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEE 468
+ + EE + +++ + + + ++ + +I+++++ +L + T E
Sbjct: 405 IVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNE 464
Query: 469 GPQ-HVTVLQ-----LKRELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAV 522
Q ++ LQ K E+K+ L V ++QK EV+E Q Q++V E
Sbjct: 465 KVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVA 524
Query: 523 S-------LKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKE---NCGDGPD 572
+ L+ Q+V+ Q ++I E +++ L ++L++ ++ V + + +
Sbjct: 525 TMLSLESELQRLQEVSGHQRKRIAE---VLNGLMKDLSEFSVIVGNGEIKLPVEISGAIE 581
Query: 573 ARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIE 632
R Y + + + + ++ +V M R + Q+L+ E
Sbjct: 582 EEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSS----CQLLISQHE 637
Query: 633 EQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLE 692
+ + L ++ + + ++ +E + + +Q ++V V L D + +TQ +D
Sbjct: 638 AKIRSL-TEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHE-VALKDKEPDTQDADEV 695
Query: 693 NE--DLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDA 750
+ +L+++ +E+ L +L+ D I E KT ++
Sbjct: 696 KKALELQMESHREAHHRQLARLR------------------------DEINEKQKTIDEL 731
Query: 751 KSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQEL----ENKDLSDVAMKVKLQKEFRKK 806
K ++++ L++ KL+ D E+ K E E +LQEL E + S +K + R+
Sbjct: 732 KDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVAREL 791
Query: 807 MDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQL----QRKLREE 862
LR +Q KK A + ++ + +Q + ++ QL ++ +R+
Sbjct: 792 QTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDN 851
Query: 863 NEKRKQLDAVIKR-----DQQKIKEIQLKTGQEEGLKPK 896
+ R +L + KR ++ K E LK +E +K K
Sbjct: 852 ADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDK 890
Score = 61.6 bits (148), Expect = 5e-09
Identities = 109/551 (19%), Positives = 225/551 (40%), Gaps = 75/551 (13%)
Query: 717 RILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELI 776
RI E +QK E+ I+ L K +D Q S + KL+ + L+
Sbjct: 408 RIAPEERQKY----------EEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLV 457
Query: 777 ETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKK----QQDSKKLASLSI 832
T+ ++++ ++LS LQ E D K +Q L++ Q S+++ S
Sbjct: 458 STRGDNEKVQ-RELSH------LQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQ 510
Query: 833 QNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEG 892
QN+ +EL Q V M + +LQR +RK++ V+ + + E + G E
Sbjct: 511 QNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEI 570
Query: 893 LKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKR 952
P G+ + +L K + EV+ V+ + ++LE L+ + ++
Sbjct: 571 KLP----------VEISGAIEEEFTVARLYISK--IKSEVKSVVKRCRQLENLQVECHRK 618
Query: 953 -----------EAIVSKKEALLQ-----------EKSHLENKKLRSSQALNTDSLKISTR 990
+ ++S+ EA ++ +K HLE S +L+ + K+ +
Sbjct: 619 MEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLE----ESYDSLSDELAKLQAQ 674
Query: 991 LNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPE 1050
+ E L +K Q + +K + + QL + R ++EK K L
Sbjct: 675 ETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDL 734
Query: 1051 EEHVLFQLEE---GIEALEAAIEYRNESIQ------NRQKSLRASFHNLSRGEANVLEKL 1101
+ + +LE+ E L++ ++ +Q R + + L A L+ L
Sbjct: 735 NQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTL 794
Query: 1102 ACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERD-NMVRELESAL--DHL 1158
L + ++ + R K E E +++++ K+ LE + + ++ L D+
Sbjct: 795 HNLRKLFVQDVTTRV--KKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNA 852
Query: 1159 KLQCD-RRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYFYKKTS 1217
L+C+ +L + + ++++ L KE EG M+ + Y+ ++ ++++ + +
Sbjct: 853 DLRCELPKLEKRLRATAERVKALEGALKEAK-EGAMKDKRRYQQEVDRIKEAVRYKSSGK 911
Query: 1218 RDHKKKLKELV 1228
R H ++ + V
Sbjct: 912 RGHSAQIAKPV 922
Score = 58.9 bits (141), Expect = 3e-08
Identities = 111/491 (22%), Positives = 213/491 (43%), Gaps = 72/491 (14%)
Query: 632 EEQDKVLHCQFSDNSDDEESEGQ--EKSGTRCRSRSWI---QKPDSVCSLVELSDTQDET 686
EE+ + L+ Q D D+ + Q EK + + + + D+ ELS Q E
Sbjct: 418 EEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSEN 477
Query: 687 Q--KSDLEN-----EDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDL 739
K +++ E+L ++ Q+SQE+ +K + ++ ++ E QK+ + + ++ +L
Sbjct: 478 DAAKDEVKEVLQALEELAVNYDQKSQEVE-EKSQQNQLLVDELSQKVATM---LSLESEL 533
Query: 740 IKELIKTGNDAKSVSK----------QYSLKVTKLEHDAEQAKVELIETQKQLQELE-NK 788
+ +G+ K +++ ++S+ V E IE + + L +K
Sbjct: 534 QRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISK 593
Query: 789 DLSDVAMKVK-------LQKEFRKKMDAAKLRVQVLQKK-QQDSKKLASL-----SIQNE 835
S+V VK LQ E +KM+ + Q Q K+ SL S++ +
Sbjct: 594 IKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELK 653
Query: 836 KRANELEQSVDHMKYQ--KIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGL 893
KR LE+S D + + K+Q Q + E K K+ D + +K E+Q+++ +E
Sbjct: 654 KR--HLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHH 711
Query: 894 KPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKRE 953
+ A D N K++ +ID L+ L+++ + ELE+L+AD +K +
Sbjct: 712 RQLARLRDEINEKQK-----TIDELKDLNQKLQL-------------ELEKLQADYEKLK 753
Query: 954 AIVSKKEALLQEKSHLENKKLRSSQAL----NTDSLKISTRLNLLEQELSEKNVQLQTST 1009
+ +K LQE + L + +S Q L T + ++ T NL + + + +++ S
Sbjct: 754 SEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSA 813
Query: 1010 AEEKT------KISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIE 1063
E +++ L+ +QL K + + R P+ E L E ++
Sbjct: 814 EMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVK 873
Query: 1064 ALEAAIEYRNE 1074
ALE A++ E
Sbjct: 874 ALEGALKEAKE 884
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 270 bits (691), Expect = 5e-72
Identities = 157/374 (41%), Positives = 231/374 (61%), Gaps = 21/374 (5%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRD-------RVFTFDFVFGKNSTQD 58
VKV VR RPL +E ++ V V + + + + FTFD VFG S Q
Sbjct: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
Query: 59 EVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIF 118
+VYN +P++ S++EGYN T+FAYGQTG+GKT+T+ G + +GIIP + IF
Sbjct: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEG---VRAIPELRGIIPNSFAHIF 131
Query: 119 QSISE-HPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVE 177
I++ F V+VSY+E+Y E++RDLL + + + L ++E I V
Sbjct: 132 GHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQR-LEVKERPDVGVYIKDLSAYVVN 190
Query: 178 SAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIV 237
+A ++ ++ +G+ R G T MNEHSSRSHAIFTI+I E +E G + +
Sbjct: 191 NADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITI-------ECSEKGIDGNMHVRM 243
Query: 238 SKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAK 297
K H VDLAGSER KTG TG+R KE+ +IN L LGNVISAL D KS+H+PYR++K
Sbjct: 244 GKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDG--KSTHVPYRNSK 301
Query: 298 ITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRID 357
+TRLL+DSLGG++KT+M + P+ N+DE++++L+YANRA+NI+NK +N P+ +
Sbjct: 302 LTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLR 361
Query: 358 EMEFEIKLLREALQ 371
+ + EI+ L++ L+
Sbjct: 362 QFQKEIEELKKKLE 375
Score = 57.4 bits (137), Expect = 1e-07
Identities = 63/286 (22%), Positives = 125/286 (43%), Gaps = 40/286 (13%)
Query: 744 IKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEF 803
++ N AK++ + + + Q + E+ E +K+L+E E SD++ + E
Sbjct: 336 LRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEE 395
Query: 804 RKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREEN 863
+ + + R + KK+ K+ + + ++ LE +D EE
Sbjct: 396 GEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLD-------------MEEE 442
Query: 864 EKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDE 923
E+ K + KR++ +K Q + + L K L+ +K G +D L K +E
Sbjct: 443 ERNKARAELEKREKDLLKAQQ----EHQSLLEKLSALE------KKVIVGGVDLLAKAEE 492
Query: 924 QKKWLDEEVEKVLNQRQELEELEADLKKRE---AIVSKKEALLQEKSHLENKKLRSSQAL 980
Q+K L+E ++ +R+ E+L +L+++E + +K LQE++ + KKL+
Sbjct: 493 QEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLK----- 547
Query: 981 NTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKE 1026
K+ T L + E+++ LQ E + E + L +E
Sbjct: 548 -----KVWTMLMAAKSEMAD----LQQEHQREIEGLLENIRQLSRE 584
Score = 53.5 bits (127), Expect = 1e-06
Identities = 77/375 (20%), Positives = 162/375 (43%), Gaps = 32/375 (8%)
Query: 524 LKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPER-RPYT 582
LKEA K+N + LVD S + N +T +++ G + P
Sbjct: 267 LKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPAD 326
Query: 583 VPFDTHLGHYIYIPSRQDSR---KVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLH 639
+D + Y ++ + +++ P D + F+ + L +EE +++
Sbjct: 327 YNYDETISTLRYANRAKNIKNKARINEDPK----DALLRQFQKEIEELKKKLEEGEEISG 382
Query: 640 CQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKID 699
S + +D++ EG+ R + +K S ++E+ DE +K+ + K+D
Sbjct: 383 SDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKA----LETKLD 438
Query: 700 CLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGND--AKSVSKQY 757
+E + +L+ E+ L +A+Q+ + L + E K++I G D AK+ ++
Sbjct: 439 MEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALE---KKVIVGGVDLLAKAEEQEK 495
Query: 758 SLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVL 817
L+ + +E + + + E + +++L+E E + L LQ+E + K K +L
Sbjct: 496 LLEESNMELEERRKRAE--QLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTML 553
Query: 818 QKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQ 877
+ + L ++ E+E +++++ QL R+LR + +D I RD
Sbjct: 554 MAAKSEMADL------QQEHQREIEGLLENIR----QLSRELRLQ---MLIIDNFIPRDY 600
Query: 878 QKIKEIQLKTGQEEG 892
Q++ E + ++ G
Sbjct: 601 QEMIENYVHWNEDIG 615
Score = 49.3 bits (116), Expect = 3e-05
Identities = 94/410 (22%), Positives = 169/410 (41%), Gaps = 101/410 (24%)
Query: 706 ELNLQKLKNSERILTEAK-----QKMRELTINIKMKEDLIKELIKTGNDAKSVSKQY-SL 759
+L+L L SER +AK Q+++E T I + + +I D KS Y +
Sbjct: 245 KLHLVDLAGSER---QAKTGATGQRLKEAT-KINLSLSTLGNVISALVDGKSTHVPYRNS 300
Query: 760 KVTKLEHD----------------AEQAKVELIETQK---QLQELENKDLSDVAMKVKLQ 800
K+T+L D A+ E I T + + + ++NK + K L
Sbjct: 301 KLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALL 360
Query: 801 KEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLR 860
++F+K+ ++ L+KK ++ ++++ I + ++ E V
Sbjct: 361 RQFQKE-------IEELKKKLEEGEEISGSDISGSEEDDDEEGEVG-------------- 399
Query: 861 EENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQK 920
E+ EKRK+ K K+ E+Q K ID +K
Sbjct: 400 EDGEKRKKRRGKKKVSPDKMIEMQAK----------------------------IDEERK 431
Query: 921 LDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQAL 980
E K LD E E+ R ELE+ E DL K + + ++LL++ S LE K +
Sbjct: 432 ALETK--LDMEEEERNKARAELEKREKDLLKAQ---QEHQSLLEKLSALEKKVI------ 480
Query: 981 NTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEK 1040
+ + + E+ L E N++L EE+ K +EQ L++E ++ ++ R +++EK
Sbjct: 481 -VGGVDLLAKAEEQEKLLEESNMEL-----EERRKRAEQ---LRRELEEKEQERLDIEEK 531
Query: 1041 LKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNL 1090
+ L E + +L++ L AA + Q Q+ + N+
Sbjct: 532 YTS---LQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENI 578
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 269 bits (688), Expect = 1e-71
Identities = 252/937 (26%), Positives = 455/937 (48%), Gaps = 125/937 (13%)
Query: 1 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEV 60
+ E +KV R RPL E + + + ++ + + FD VF +++Q++V
Sbjct: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKF--QGEDTVVIASKPYAFDRVFQSSTSQEQV 61
Query: 61 YNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQS 120
YN C K +V ++EGYN T+FAYGQT SGKT+T+ G EG GIIPR +Q+IF
Sbjct: 62 YNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGK--LHDPEGM-GIIPRIVQDIFNY 118
Query: 121 I-SEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESA 179
I S +++F++KVSY E+Y + +RDLL++ S +L + ED+ + G E V S
Sbjct: 119 IYSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLSVHEDKNRVPYVKGCTERFVCSP 176
Query: 180 GEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSK 239
EVM ++ G + RH T MNEHSSRSH+IF I++ Q + E G K
Sbjct: 177 DEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSG----------K 226
Query: 240 FHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKIT 299
+ VDLAGSE+V+KTG G E+ IN L ALGNVISAL + S+++PYRD+K+T
Sbjct: 227 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE---GSTYVPYRDSKMT 283
Query: 300 RLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESD----R 355
R+L+DSLGG+ +T ++ C SPSS N E+ ++L + RA+ I+N VN ++ +
Sbjct: 284 RILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKK 343
Query: 356 IDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRI-HSLEEQVAQLQGECLGYQCC 414
++ + + K+LR +Q + ++NR + +T I +++ A L+ +
Sbjct: 344 YEKEKEKNKILRNTIQWLE------NELNRWRNGETVPIDEQFDKEKANLEAFTVDKDIT 397
Query: 415 VEE-----AFTFLVDLKDTVR-------------LNEKQQHKLQEWFNMIQEVRKAVLTS 456
+ A + + D R L++K + ++ + ++++++ +L
Sbjct: 398 LTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDE-EINQQSQLVEKLKTQMLDQ 456
Query: 457 FRGIGGTASLEEGPQ-HVTVLQL-----KRELKKCQCVLAADEVVFNQKELEVKELKNQV 510
+ T ++ Q + LQ K E+K+ L V ++QK EV++ +
Sbjct: 457 EELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEY 516
Query: 511 QMMVQENKGHAVSL----KEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSV-TSSAKE 565
+++ E + +L E QK+ + N + ++ L ++L ++ ++V + K+
Sbjct: 517 ELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQ 576
Query: 566 NCGDGP-DARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRS 624
G G D R Y + + + + +S + ++ M ++ A + R
Sbjct: 577 PEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRI 636
Query: 625 QM----------LLGHIEEQDKVLHCQFSDNSDD-EESEGQEKSGTRCRSR-SWIQKPDS 672
L ++E++ + L S++ + QEK + + +Q +
Sbjct: 637 SQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANE 696
Query: 673 VCSLVE-------------LSDTQDETQK-----SDLENEDLKIDCLQESQELNLQKLKN 714
V VE +S +DE + +DL++++ K+ QE + +KLK
Sbjct: 697 VKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKA 756
Query: 715 SERILTEAKQKMRELTI----------NIK-MKEDLIKELIKTGNDAKSVSKQYSLKVTK 763
+++ E +K+ ELT+ ++K ++E + KEL N K + + +V K
Sbjct: 757 TDQ---EKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKK 813
Query: 764 ---LEHD------AEQAKVELIETQ-KQLQELENKDLSDVA-MKVKLQKEFRKKMDAAKL 812
++ D A++ K+ +E +QL ++ + + D A ++ +L K K++ A
Sbjct: 814 SAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK-LEKRLRATAE 872
Query: 813 RVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMK 849
RV+ L+ +++K+ AS ++ KR +Q VD +K
Sbjct: 873 RVKALESALKEAKENAS---RDRKR---YQQEVDRIK 903
Score = 60.8 bits (146), Expect = 9e-09
Identities = 104/500 (20%), Positives = 215/500 (43%), Gaps = 78/500 (15%)
Query: 632 EEQDKVLHCQFSDNSDDEESEGQ--EKSGTRCRSRSWI-----QKPDSVCSLVELSDTQD 684
EE+ L+ Q D ++ + Q EK T+ + + + D++ + + ++
Sbjct: 422 EEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAEN 481
Query: 685 ETQKSDLEN-----EDLKIDCLQESQELNLQKLKNSERILTEAKQK-------------M 726
+ K +++ E+L ++ Q+SQE+ K K E + E QK +
Sbjct: 482 DASKEEVKEVLQALEELAVNYDQKSQEVE-DKTKEYELLSDELNQKSATLASIDAELQKL 540
Query: 727 RELTINIK-----MKEDLIKELIKTG-----NDAKS------VSKQYSLKVTKLEHDAEQ 770
+E+T + K M L+K+L + G ND K + +++++ + +
Sbjct: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600
Query: 771 AKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASL 830
K +++ KQL+ + + K +E K++ A +LR+ Q K+ SL
Sbjct: 601 VKT-MVKRCKQLESTQTESN-------KKMEENEKELAACQLRIS------QHEAKIKSL 646
Query: 831 S--IQN-EKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQK-IKEIQLK 886
+ +QN E++ +LE+SVD + + +QL+ + + +++ L+ V ++ K E Q++
Sbjct: 647 TEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQ 706
Query: 887 TGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELE 946
+ +E K + D K + I LQ QK L++E +V +++ + + E
Sbjct: 707 SHRETHQKQISSLRDEVEAKAK-----LITDLQD-QNQKMMLEQERLRVEHEKLKATDQE 760
Query: 947 ADLKKREAIV--SKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELS---EK 1001
K E V ++E Q+ LE + Q L+ L Q+L+ +K
Sbjct: 761 KSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLH-------NLRKLFVQDLATRVKK 813
Query: 1002 NVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEG 1061
+ ++ + +++ L+ +QL K + + R P+ E L E
Sbjct: 814 SAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAER 873
Query: 1062 IEALEAAIEYRNESIQNRQK 1081
++ALE+A++ E+ +K
Sbjct: 874 VKALESALKEAKENASRDRK 893
Score = 53.1 bits (126), Expect = 2e-06
Identities = 84/401 (20%), Positives = 166/401 (41%), Gaps = 33/401 (8%)
Query: 856 QRKLREENEKR-KQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGS 914
+RK EE K KQLD K +EI ++ E LK + D + R+
Sbjct: 418 RRKCEEEIAKLYKQLD-------DKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNM 470
Query: 915 IDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKL 974
L +L + EEV++VL Q LEEL + ++ V K + S N+K
Sbjct: 471 QAELNRLQAENDASKEEVKEVL---QALEELAVNYDQKSQEVEDKTKEYELLSDELNQKS 527
Query: 975 RSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRR 1034
+ +++ + K+ N ++ +E L AE + +V Q E +
Sbjct: 528 ATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNN-DVKQPEGTGM---- 582
Query: 1035 HNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGE 1094
+DE+ R+ + + + + + + LE+ N+ ++ +K L A +S+ E
Sbjct: 583 --IDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHE 640
Query: 1095 ANVLEKLACLSPVE-----IRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVR 1149
A + L VE + + ++V LR E+ ++ E + KV + + +
Sbjct: 641 AKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLN-KVQTANEVKQ 699
Query: 1150 ELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKD 1209
+E + + ++++ + E E K +L+ ++Q+ + ++E ++L +
Sbjct: 700 AVEQQIQSHRETHQKQISSLRDEVEAKAKLIT-DLQDQNQKMMLEQ--------ERLRVE 750
Query: 1210 LYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLK 1250
K T ++ +KL EL RR+ A + + + V K
Sbjct: 751 HEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAK 791
Score = 38.9 bits (89), Expect = 0.035
Identities = 45/197 (22%), Positives = 88/197 (44%), Gaps = 26/197 (13%)
Query: 1118 NKVVNLREAERKQQLYNEEMKMKVL-ERDNMVRELESALDHLKLQCDRRLTLQQ-KEHEQ 1175
N+ L E + Q L EE+ ++DNM EL +LQ + + ++ KE Q
Sbjct: 440 NQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELN------RLQAENDASKEEVKEVLQ 493
Query: 1176 KMQLLLHHF--KEQDGEGIMETFKTYEDKIQQ-------LEKDLYFYKKTSRDHKKKLKE 1226
++ L ++ K Q+ E + ++ D++ Q ++ +L K+ + KK+ E
Sbjct: 494 ALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAE 553
Query: 1227 LVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEEL--------KWASRPESMKLSGRERE 1278
++ ++ LA + V +PEG GM+ EE K S ++M ++ E
Sbjct: 554 MMASLLK-DLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLE 612
Query: 1279 MDSSASSLRTQPNPQKL 1295
+ S+ + + N ++L
Sbjct: 613 STQTESNKKMEENEKEL 629
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 268 bits (684), Expect = 4e-71
Identities = 198/641 (30%), Positives = 325/641 (50%), Gaps = 118/641 (18%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRV--------FTFDFVFGKNSTQ 57
+KV R RPL KE H+ + + QV + R FTFD V+ +S Q
Sbjct: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
Query: 58 DEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEI 117
++Y+ ++PL+ S+++G+N TVFAYGQTG+GKTYT+ G + + +G+IP A + I
Sbjct: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPEL---RGVIPNAFEHI 127
Query: 118 FQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVE 177
F IS + + V+ SY+E+Y+E++RDLL E K L ++E+ + I +
Sbjct: 128 FTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPG-KRLELKENPETGVYIKDLSSFVTK 186
Query: 178 SAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIV 237
+ E+ ++ +GN R G+T MNE SSRSHAIF I++ E +E GS V
Sbjct: 187 NVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITV-------ECSERGSDGQDHIRV 239
Query: 238 SKFHFVDLAGSERVTKTG-NT-----------------------GERFKESIQINSGLLA 273
K + VDLAGSER K G NT GER KE+ +IN L A
Sbjct: 240 GKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSA 299
Query: 274 LGNVISALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLK 333
LGNVI+AL R S+HIPYRD+K+TRLL+DSLGG+AKT+M+ + P+S ++DESL++L+
Sbjct: 300 LGNVIAALAGNR--STHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLR 357
Query: 334 YANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQ-------------------- 373
+ANRA+NI+NKP VN P+ + E + EI L+ L+ +
Sbjct: 358 FANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSA 417
Query: 374 ----------QAGVSQTTQINR----------EGSPDTNRIHSLEEQVAQLQGECLGYQC 413
+A V++ N E + + N + L+EQ +L+ E Q
Sbjct: 418 PPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQ- 476
Query: 414 CVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRK------------AVLTSFRGIG 461
D ++E++Q L+E M++++R+ + S IG
Sbjct: 477 ------------DDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIG 524
Query: 462 GTASLEEGPQHVTVLQLKR----ELKKCQCVLAADEVVFNQKELEVK----ELKNQVQMM 513
G ++ + +L+LKR E K+ + + + ++ +++ +E++ L+ +V++
Sbjct: 525 GRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVK 584
Query: 514 VQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTK 554
++ K L+ + + Q+++ I + +++ E T+
Sbjct: 585 TKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTR 625
Score = 35.4 bits (80), Expect = 0.39
Identities = 57/298 (19%), Positives = 125/298 (41%), Gaps = 63/298 (21%)
Query: 817 LQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRD 876
L+K ++ + ++ EK A + ++S+ + QK+ EK K L+ ++R+
Sbjct: 453 LEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLL--------EEKEKMLED-LRRE 503
Query: 877 QQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVL 936
QQ + + K A K G +DH +EQ+K L+ + +++
Sbjct: 504 QQATELLAAK-------------YKAMESKLLIGGRNIMDH---TNEQQKMLELKRQEIA 547
Query: 937 NQRQELEELEADLKKREAIVSKKEAL---LQEKSHLENKKLRSSQALNTDSLKISTRLNL 993
Q++ E++ ++ R+ + LQ++ ++ KKL+ K+ +L
Sbjct: 548 EQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLK----------KLYAKLQA 597
Query: 994 LEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDE---------KLKNG 1044
++ E+ +++ +E ++ + +E Q E+ + K ++ + E K+ N
Sbjct: 598 VKAEIQDQH--------DEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNR 649
Query: 1045 RVLSPEEEHVLFQ--LEEGIEALE------AAIEYRNESIQNRQKSLRASFHNLSRGE 1094
L EEE FQ + G+ + + +A+ Y+ Q + ++ H R E
Sbjct: 650 LFLDCEEEQWKFQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAE 707
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 266 bits (680), Expect = 1e-70
Identities = 331/1320 (25%), Positives = 575/1320 (43%), Gaps = 184/1320 (13%)
Query: 6 VKVAVRIRPLLCKE--ALHNHQVCVRVIPNSQQVIIGRD--RVFTFDFVFGKNSTQDEVY 61
+KV VRIRP + A +C+ V+ ++ + + FTFD V ++TQ+ V+
Sbjct: 27 IKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLHSNPEPKTFTFDHVADVDTTQESVF 86
Query: 62 NTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTI-GGGHIASVVEGQKGIIPRAIQEIFQS 120
T K +V S + GYN T+FAYGQTGSGKT+T+ G + +G+IPR+ + +F
Sbjct: 87 ATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIPRSFEYLFSL 146
Query: 121 ISEHPSI-----DFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECH 175
I F K S+IE+Y E + DLL+ ++ L++RE K +VGA E
Sbjct: 147 IDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLD--SASAGLYLREHIKKGVFVVGAVEQV 204
Query: 176 VESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRH 235
V SA E +L G R +T MN SSRSHA+FTI+I + K+ E +
Sbjct: 205 VTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNEIVNIRT------ 258
Query: 236 IVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRR-KSSHIPYR 294
S + VDLAGSER T G R KE+ IN L LG VI+AL D K H+ YR
Sbjct: 259 --SLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQRHVCYR 316
Query: 295 DAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESD 354
D+K+T LL+DSLGG+AKT +I V P S F E+L++L +A RA+ I+NK VN + +
Sbjct: 317 DSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQGN 376
Query: 355 RIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIH-----------------SL 397
+ +++ E+K L+E L +G + TN + SL
Sbjct: 377 -VSQLQAEVKRLKEQLAELASGQTPPESFLTRDKKKTNYMEYFQEAMLFFKKSEQEKKSL 435
Query: 398 EEQVAQLQGECLGYQCCVEEAFTFLVDLKDTV-------------RLNEKQQHKLQEWFN 444
E+V QL+ L + ++ + +D + L E+Q L E N
Sbjct: 436 IEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLEKLHKESRGGFLPEEQDRLLSELRN 495
Query: 445 MIQEVRKAVLTSFRGIG---GTASLEEGPQHVTVLQ-LKRELKKCQCVLAADEVVFNQKE 500
IQ +R+ + R SL E + + +L+ +KR + +A E F++
Sbjct: 496 EIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPVKRAQEMDAQTIAKLEKAFSEIS 555
Query: 501 LEVKELKNQVQMMVQENKGHAV-SLKEAQKVNRLQ---------------NEKIIEQQLL 544
K KNQ + K + + E K LQ E ++QL
Sbjct: 556 GMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQLLQIQTELNNSKQEYEEFKELTRKRQLE 615
Query: 545 VDQLSEELTKLNLSVTS--SAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSR 602
++ + L K NL++ + A + C +++ + T+ T + SR +
Sbjct: 616 LESELQSLQKANLNLENLLEATKACKRQEVSQLNKIHAETLKIITTPTKAYQLHSRPVPK 675
Query: 603 KVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEG-QEKSGTRC 661
SP M S F T++ +L + +L+ +++ E E+ T
Sbjct: 676 ---LSPEMGS----FGSLYTQNSSIL-----DNDILNEPVPPEMNEQAFEAISEELRTVQ 723
Query: 662 RSRSWIQK--PDSVCSLVELSDTQDETQKSDLENEDL----KIDCLQESQELNLQKLKNS 715
S +Q + ++L D+ + + ++L +ID ++ +EL L +L
Sbjct: 724 EQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEEL-LSQLNVL 782
Query: 716 ERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVEL 775
E+ L E + K L + DL L + SV +YS T E + +
Sbjct: 783 EKQLQETQTKNDFLKSEV---HDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERH 839
Query: 776 IETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNE 835
+ Q QL L ++ + K LQ + + K + L + Q+ KK +NE
Sbjct: 840 MHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKK------ENE 893
Query: 836 KRANELEQSVDHMKYQ-----KIQLQRKLREENEKR---KQLDAVIKRDQQKIKEIQLKT 887
++L ++ ++ + K+ LQ + +EN + K L+AV + Q++ + + +
Sbjct: 894 TLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQM 953
Query: 888 GQ----EEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELE 943
+ EE L + + + R D + ++ E + + E+ E + +QEL+
Sbjct: 954 AKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELK 1013
Query: 944 ELEADLKKREAIVSKKEA-LLQEKSHLENKKLRSSQALN------------TDSLKISTR 990
++ + K A+V ++E+ +L +K ++ L+ + L D + +
Sbjct: 1014 DI--NCKYNSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQ 1071
Query: 991 LNLLEQELSEKNVQLQTSTAEEKTK----ISEQVEVLQKEKDQLQKRRHNVDEKLKN--- 1043
LN+L E S+K+ L S EE TK I E L ++K++++++++ + K++
Sbjct: 1072 LNML-TEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEH 1130
Query: 1044 ----------------------GRVLSPEEEHV------LFQLEEGIEALEAAIEYRNES 1075
++L +E+ + LE + L E +N
Sbjct: 1131 VMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAE 1190
Query: 1076 IQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFN---------KVVNLREA 1126
I ++ LR NL ++EK L ++ I + N ++ N +E
Sbjct: 1191 ILRMKEQLR-EMENLRLESQQLIEKNWLLQG-QLDDIKRQKENSDQNHPDNQQLKNEQEE 1248
Query: 1127 ERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQC-------DRRLTLQQKEHEQKMQL 1179
K++L ++ ++L+ + E++SAL + +++C +R TL+ K ++K QL
Sbjct: 1249 SIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQL 1308
Score = 72.8 bits (177), Expect = 2e-12
Identities = 145/765 (18%), Positives = 302/765 (39%), Gaps = 73/765 (9%)
Query: 327 ESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINRE 386
E+L + +A + ++P SPE +L +Q + + +N
Sbjct: 654 ETLKIITTPTKAYQLHSRPVPKLSPEMGSFG-----------SLYTQNSSILDNDILNEP 702
Query: 387 GSPDTNR--IHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFN 444
P+ N ++ E++ +Q + Q ++E + L+ V E ++QE F
Sbjct: 703 VPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELF- 761
Query: 445 MIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQ------------LKRELKKCQCVLAAD 492
S I T EE + VL+ LK E+ + VL +
Sbjct: 762 -----------SSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSA 810
Query: 493 EVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLV----DQL 548
+ + +LE K + + + ++ RL+NEK++E + + D L
Sbjct: 811 DKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNL 870
Query: 549 SE----ELTKLNLSVTSSAKENCGDGPDAR-IPERRPYTVPFDTHLGHYIYIPSRQDSRK 603
E E+ +L+ ++ + KEN D + E + L S++
Sbjct: 871 QEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKE 930
Query: 604 VHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRS 663
+ ++ + QM +++ ++ L S E+S +K
Sbjct: 931 ILKVLEAVRQEKQKETAKCEQQM--AKVQKLEESLLATEKVISSLEKSRDSDKKVVADLM 988
Query: 664 RSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAK 723
+ SVC E DT K +L++ + K + +E + +K E + + K
Sbjct: 989 NQIQELRTSVCEKTETIDTL----KQELKDINCKYNSALVDREESRVLIKKQEVDILDLK 1044
Query: 724 QKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQ 783
+ +R ++ ++ D++ E + + ++ + S K + L A++ EL + + +Q
Sbjct: 1045 ETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQE---ELTKKEALIQ 1101
Query: 784 ELENKDLSDVAMKVKLQK-EFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELE 842
EL++K L+ +V+ +K E+ KM + + + Q K K E
Sbjct: 1102 ELQHK-LNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQE 1160
Query: 843 QSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPK----AE 898
Q ++ + K L+ + + NE R+ +A I R +++++E++ + + L K
Sbjct: 1161 QEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQG 1220
Query: 899 DLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEE------VEKVLNQRQELEELEADLKKR 952
LD ++ D+ Q +EQ++ + E VE++L + +LEE+++ L +
Sbjct: 1221 QLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSALYNK 1280
Query: 953 EAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEE 1012
E + ++ LE+K + + L + ++ QE+ Q++ AEE
Sbjct: 1281 EMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVE-CLAEE 1339
Query: 1013 KTKISEQVEVLQKEKDQLQKRRHNV-----DEKLKNGRVLSPEEE 1052
K+ + QK + ++ ++ NV EKL+ V E++
Sbjct: 1340 NGKLVGHQNLHQKIQYVVRLKKENVRLAEETEKLRAENVFLKEKK 1384
Score = 60.5 bits (145), Expect = 1e-08
Identities = 92/533 (17%), Positives = 225/533 (42%), Gaps = 50/533 (9%)
Query: 671 DSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELT 730
+S L + D E K +++ + ++ E L N +L K++ +L+
Sbjct: 858 ESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLS 917
Query: 731 INIKM-KEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKD 789
+ + KE+ KE++K + ++ + K + ++ + L+ T+K + LE
Sbjct: 918 LQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSR 977
Query: 790 LSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKL-----ASLSIQNEKRANELEQS 844
SD + L + ++ + + + + +Q+ K + ++L + E R +Q
Sbjct: 978 DSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQE 1037
Query: 845 VDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACN 904
VD + K L+ ++ E+ +R L + +++ + + + GL A++
Sbjct: 1038 VDILDL-KETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQE----E 1092
Query: 905 LKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQ-ELEELEADLKKREAIVSKKEALL 963
L +++ + H KL+++K EEVE+ N+ ++ +LE + +
Sbjct: 1093 LTKKEALIQELQH--KLNQKK----EEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPP 1146
Query: 964 QEKSHL------ENKKLRSSQALNTDSLKISTRLN------------LLEQELSEKNVQL 1005
++HL + +++ +A T + T+LN + EQ +N++L
Sbjct: 1147 HFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRL 1206
Query: 1006 QTSTAEEKTKISE-QVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEA 1064
++ EK + + Q++ ++++K+ + H +++LKN + S +E ++ E +
Sbjct: 1207 ESQQLIEKNWLLQGQLDDIKRQKEN-SDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLK 1265
Query: 1065 LEAAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLR 1124
++A +E ++ N++ + R LE A ++R+ L
Sbjct: 1266 MKADLEEVQSALYNKEMECLRMTDEVER--TQTLESKAFQEKEQLRS----------KLE 1313
Query: 1125 EAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKM 1177
E +++ ++EM+M + + + E + H L + ++ K+ ++
Sbjct: 1314 EMYEERERTSQEMEMLRKQVECLAEENGKLVGHQNLHQKIQYVVRLKKENVRL 1366
Score = 55.5 bits (132), Expect = 4e-07
Identities = 134/665 (20%), Positives = 251/665 (37%), Gaps = 121/665 (18%)
Query: 712 LKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEH----- 766
+KN + + + + +L +K ++ + EL +S + K +E+
Sbjct: 363 IKNKAVVNEDTQGNVSQLQAEVKRLKEQLAELASGQTPPESFLTRDKKKTNYMEYFQEAM 422
Query: 767 ----DAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQ- 821
+EQ K LIE QL++L K + K+ +FR+ +R++ L K+
Sbjct: 423 LFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSN-KMIVKFREDQI---IRLEKLHKESR 478
Query: 822 -----QDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQR-KLREENEKRKQLDAVIKR 875
++ +L S ++NE + EQ H + K ++ LREEN + + L+ V KR
Sbjct: 479 GGFLPEEQDRLLS-ELRNEIQTLR-EQIEHHPRVAKYAMENHSLREENRRLRLLEPV-KR 535
Query: 876 DQQ--------------KIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKL 921
Q+ +I ++ ++G PKA+ + C + + +Q
Sbjct: 536 AQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQK-EPCLFANTEKLKAQLLQIQTE 594
Query: 922 DEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALN 981
K EE +++ +RQ ELE++L+ + E LL+ + +++ ++
Sbjct: 595 LNNSKQEYEEFKELTRKRQL--ELESELQSLQKANLNLENLLEATKACKRQEVSQLNKIH 652
Query: 982 TDSLKIST-----------------------------RLNLLEQEL------SEKNVQLQ 1006
++LKI T ++L+ ++ E N Q
Sbjct: 653 AETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDILNEPVPPEMNEQAF 712
Query: 1007 TSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALE 1066
+ +EE + EQ+ LQ + D EEEH +L++ ++ LE
Sbjct: 713 EAISEELRTVQEQMSALQAKLD---------------------EEEHKNLKLQQHVDKLE 751
Query: 1067 AAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREA 1126
E + + L + NVLEK + + + + V L A
Sbjct: 752 HHSTQMQELFSSERIDWTKQQEEL-LSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSA 810
Query: 1127 ERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKE 1186
+++ E ++ +L H++LQ D +K E K L
Sbjct: 811 DKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACL------- 863
Query: 1187 QDGEGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGD 1246
QD ++ +E I QL ++L +KK + K L L+ +L +E +
Sbjct: 864 QDSYDNLQEIMKFE--IDQLSRNLQNFKKENETLKSDLNNLM------ELLEAEKERNNK 915
Query: 1247 GVLKPEGGGMLSEELKWASRPESMKL--SGREREMDSSASSLRTQPNPQKLWEDIPELPP 1304
L+ EE K S E +K+ + R+ + +A + QKL E +
Sbjct: 916 LSLQ-------FEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEK 968
Query: 1305 IHSSL 1309
+ SSL
Sbjct: 969 VISSL 973
Score = 45.8 bits (107), Expect = 3e-04
Identities = 111/612 (18%), Positives = 235/612 (38%), Gaps = 137/612 (22%)
Query: 317 CVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAG 376
C+ S N E + + +RN++N N + +SD + ME L EA + +
Sbjct: 862 CLQDSYDNLQEIMK-FEIDQLSRNLQNFKKENETLKSDLNNLME-----LLEAEKERNNK 915
Query: 377 VSQTTQINREGSPDT--NRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEK 434
+S + ++E S + ++ ++ + +C V++ L+ + + EK
Sbjct: 916 LSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEK 975
Query: 435 QQHK----LQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKRELKKCQCVLA 490
+ + + N IQE+R +V T+ LK+ELK C
Sbjct: 976 SRDSDKKVVADLMNQIQELRTSVCEKTE---------------TIDTLKQELKDINCKYN 1020
Query: 491 A-------DEVVFNQKELEVKELKN-------------------------QVQMMVQENK 518
+ V+ ++E+++ +LK Q+ M+ + +K
Sbjct: 1021 SALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASK 1080
Query: 519 GHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEEL----TKLNLSVTSSAKENCGDGPDAR 574
H+ L+ AQ+ + I E Q ++Q EE+ + N + D +
Sbjct: 1081 KHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQ 1140
Query: 575 IPERRPYTVPFDTHLGHYIYIPSR--QDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIE 632
P+ P+ F THL + + +D R TS + L+ +
Sbjct: 1141 SPKTPPH---FQTHLAKLLETQEQEIEDGRASKTS----------------LEHLVTKLN 1181
Query: 633 EQDKVLHCQFSDNSDD-EESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDL 691
E +V + + + E E + ++W+ + +L D + + + SD
Sbjct: 1182 EDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQG-------QLDDIKRQKENSDQ 1234
Query: 692 ENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAK 751
+ D Q+LKN E ++ ++E K +++E++K D +
Sbjct: 1235 NHPD-------------NQQLKN------EQEESIKERL----AKSKIVEEMLKMKADLE 1271
Query: 752 SVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAK 811
V ++ E + + + ++ Q LE+K + +++ R K++
Sbjct: 1272 EVQSAL--------YNKEMECLRMTDEVERTQTLESKAFQE-------KEQLRSKLE--- 1313
Query: 812 LRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMK-YQKIQLQRKLREENEKRKQLD 870
++ +++++ S+++ L Q E A E + V H +QKIQ +L++EN + +
Sbjct: 1314 ---EMYEERERTSQEMEMLRKQVECLAEENGKLVGHQNLHQKIQYVVRLKKENVRLAEET 1370
Query: 871 AVIKRDQQKIKE 882
++ + +KE
Sbjct: 1371 EKLRAENVFLKE 1382
Score = 45.4 bits (106), Expect = 4e-04
Identities = 64/314 (20%), Positives = 138/314 (43%), Gaps = 26/314 (8%)
Query: 679 LSDTQDETQKSDLENEDLKIDCLQESQELNLQK------LKNSERILTEAKQKMRELTIN 732
L Q+E K + ++L+ Q+ +E+ +K ++ E ++ A + +
Sbjct: 1086 LQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTP 1145
Query: 733 IKMKEDLIKELIKTGN----DAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENK 788
+ L K L++T D ++ VTKL D E E++ ++QL+E+EN
Sbjct: 1146 PHFQTHLAK-LLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENL 1204
Query: 789 DLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHM 848
L + ++ + ++D K + + + D+++L + ++ K + V+ M
Sbjct: 1205 RLESQQL-IEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEM 1263
Query: 849 KYQKIQLQRKLREENEKRKQLDAVIKRDQ-QKIKEIQLKTGQE-EGLKPKAEDLDACNLK 906
K L+ + K+++ + D+ ++ + ++ K QE E L+ K E++ +
Sbjct: 1264 LKMKADLEEV--QSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYE---E 1318
Query: 907 RRKGSFGSIDHLQKLDEQKKWLDEEVEKVL---NQRQELEELEADLKKREAIVSKKEALL 963
R + S ++ L +Q + L EE K++ N Q+++ + K+ + + E L
Sbjct: 1319 RERTS----QEMEMLRKQVECLAEENGKLVGHQNLHQKIQYVVRLKKENVRLAEETEKLR 1374
Query: 964 QEKSHLENKKLRSS 977
E L+ KK S
Sbjct: 1375 AENVFLKEKKRSES 1388
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 250 bits (638), Expect = 8e-66
Identities = 178/483 (36%), Positives = 255/483 (52%), Gaps = 56/483 (11%)
Query: 1 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVII-------------GRDRVFTF 47
M + VKVAVRIRP+ +E H CV V ++ +VI+ G+ +VF +
Sbjct: 1 MGDSKVKVAVRIRPMNRRET-DLHTKCV-VDVDANKVILNPVNTNLSKGDARGQPKVFAY 58
Query: 48 DFVFG--------KNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHI 99
D F K + QD V+ + ++ + +GYNA +FAYGQTGSGK+YT+ G
Sbjct: 59 DHCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMG--- 115
Query: 100 ASVVEGQKGIIPRAIQEIFQSIS--EHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLH 157
Q G+IPR +F+ E+ F V+VSY+E+Y E +RDLL+ + S + L
Sbjct: 116 ---TADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLK 172
Query: 158 IREDEKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQ 217
+RE + G + V S ++ SL+ GN +R T MNE SSRSHA+F I++
Sbjct: 173 VREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTH 232
Query: 218 VHKNMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNV 277
++++ G V K VDLAGSER TKTG G+R KE IN L LG V
Sbjct: 233 TLYDVKSGTSGEK------VGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLV 286
Query: 278 ISALGDP---RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKY 334
ISAL D + K+ +PYRD+ +T LLKDSLGG++KT M+ VSP++ N+DE+L++L+Y
Sbjct: 287 ISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRY 346
Query: 335 ANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPD---- 390
A+RA++I N VN P + I ++ E++ LRE L +A S + E S
Sbjct: 347 ADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEESEKLIQE 406
Query: 391 -----TNRIHSLEE--QVAQLQGECLGYQ-----CCVEEAFTFLVDLKDTVRLNEKQQHK 438
++ EE Q Q Q E LG V + FLV+L LNE +
Sbjct: 407 MTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGDDKCFLVNLNADPALNELLVYY 466
Query: 439 LQE 441
L+E
Sbjct: 467 LKE 469
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 248 bits (632), Expect = 4e-65
Identities = 170/522 (32%), Positives = 276/522 (52%), Gaps = 53/522 (10%)
Query: 1 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRD-----RVFTFDFVFGKNS 55
M VKVAVR+RP +E + +++ NS +I ++ + F+FD+ + ++
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHT 60
Query: 56 T--------QDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQK 107
+ Q+ VYN K ++L EGYN +FAYGQTG+GK+YT+ G E Q
Sbjct: 61 SPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQ----EESQA 116
Query: 108 GIIPRAIQEIFQSISEH--PSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGN 165
GIIP+ +E+F+ I+++ + ++V+VSY+E+Y E +RDLL + +L +RE
Sbjct: 117 GIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNK-GNLRVREHPLLG 175
Query: 166 TVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAA 225
+ + V S ++ L++ GN AR T MNE SSRSHA+FTI Q
Sbjct: 176 PYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQ------KK 229
Query: 226 EDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGD-- 283
D VSK VDLAGSER TG G R KE IN L LG VISAL +
Sbjct: 230 HDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVS 289
Query: 284 -PRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIR 342
++K+ IPYRD+ +T LL+++LGG+++T M+ +SP+ N+DE+L++L+YA+RA+ I+
Sbjct: 290 KKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIK 349
Query: 343 NKPTVNFSPESDRIDEMEFEIKLLREALQSQQAG-VSQTTQINREGSPDT---------N 392
+N P + + E++ E+ L++ L++Q G + T+ + SP +
Sbjct: 350 CNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLT 409
Query: 393 RIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTV-RLNEKQQHKLQEWFNMIQEVRK 451
+ S++E++ G EEA L + + + LNE + KL++ I+ R+
Sbjct: 410 SVTSIQERIMSTPGG--------EEAIERLKESEKIIAELNETWEEKLRK-TEAIRMERE 460
Query: 452 AVL----TSFRGIGGTASLEEGPQHVTVLQLKRELKKCQCVL 489
A+L + R GGT + + ++ L + +C+L
Sbjct: 461 ALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLL 502
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 248 bits (632), Expect = 4e-65
Identities = 170/522 (32%), Positives = 276/522 (52%), Gaps = 53/522 (10%)
Query: 1 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRD-----RVFTFDFVFGKNS 55
M VKVAVR+RP +E + +++ NS +I ++ + F+FD+ + ++
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHT 60
Query: 56 T--------QDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQK 107
+ Q+ VYN K ++L EGYN +FAYGQTG+GK+YT+ G E Q
Sbjct: 61 SPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQ----EESQA 116
Query: 108 GIIPRAIQEIFQSISEH--PSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGN 165
GIIP+ +E+F+ I+++ + ++V+VSY+E+Y E +RDLL + +L +RE
Sbjct: 117 GIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNK-GNLRVREHPLLG 175
Query: 166 TVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAA 225
+ + V S ++ L++ GN AR T MNE SSRSHA+FTI Q
Sbjct: 176 PYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQ------KK 229
Query: 226 EDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGD-- 283
D VSK VDLAGSER TG G R KE IN L LG VISAL +
Sbjct: 230 HDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVS 289
Query: 284 -PRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIR 342
++K+ IPYRD+ +T LL+++LGG+++T M+ +SP+ N+DE+L++L+YA+RA+ I+
Sbjct: 290 KKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIK 349
Query: 343 NKPTVNFSPESDRIDEMEFEIKLLREALQSQQAG-VSQTTQINREGSPDT---------N 392
+N P + + E++ E+ L++ L++Q G + T+ + SP +
Sbjct: 350 CNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLT 409
Query: 393 RIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTV-RLNEKQQHKLQEWFNMIQEVRK 451
+ S++E++ G EEA L + + + LNE + KL++ I+ R+
Sbjct: 410 SVTSIQERIMSTPGG--------EEAIERLKESEKIIAELNETWEEKLRK-TEAIRMERE 460
Query: 452 AVL----TSFRGIGGTASLEEGPQHVTVLQLKRELKKCQCVL 489
A+L + R GGT + + ++ L + +C+L
Sbjct: 461 ALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLL 502
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 247 bits (631), Expect = 5e-65
Identities = 155/398 (38%), Positives = 228/398 (57%), Gaps = 35/398 (8%)
Query: 1 MEEIPVKVAVRIRPL---------LCKEALHNHQVCVRVIP-NSQQVIIGRDRVFTFDFV 50
M + VKVAVR+RP+ C + +Q + P N++Q +VF FD+
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC 60
Query: 51 FG--------KNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASV 102
F K + Q+ V+ + ++ +GYNA +FAYGQTGSGK++++ G
Sbjct: 61 FWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH----- 115
Query: 103 VEGQKGIIPRAIQEIFQSIS--EHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIRE 160
Q G+IPR +F+ IS ++ S F V+VSY+E+Y E +RDLL+ + S + L +RE
Sbjct: 116 -AEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVRE 174
Query: 161 DEKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHK 220
+ + G + V S ++ SL+ GN +R T MNE SSRSHA+F I I Q
Sbjct: 175 HKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLY 234
Query: 221 NMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISA 280
++++ G VSK VDLAGSERV+KTG GER KE IN L LG VIS+
Sbjct: 235 DLQSGNSGEK------VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISS 288
Query: 281 LGDP---RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANR 337
L D + KS +PYRD+ +T LLKD+LGG+++T MI +SP++ N++E+L++L+YA+R
Sbjct: 289 LADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADR 348
Query: 338 ARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQA 375
A+ I N VN P + I E+ E++ LRE L +A
Sbjct: 349 AKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEA 386
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 247 bits (631), Expect = 5e-65
Identities = 155/398 (38%), Positives = 228/398 (57%), Gaps = 35/398 (8%)
Query: 1 MEEIPVKVAVRIRPL---------LCKEALHNHQVCVRVIP-NSQQVIIGRDRVFTFDFV 50
M + VKVAVR+RP+ C + +Q + P N++Q +VF FD+
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC 60
Query: 51 FG--------KNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASV 102
F K + Q+ V+ + ++ +GYNA +FAYGQTGSGK++++ G
Sbjct: 61 FWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH----- 115
Query: 103 VEGQKGIIPRAIQEIFQSIS--EHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIRE 160
Q G+IPR +F+ IS ++ S F V+VSY+E+Y E +RDLL+ + S + L +RE
Sbjct: 116 -AEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVRE 174
Query: 161 DEKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHK 220
+ + G + V S ++ SL+ GN +R T MNE SSRSHA+F I I Q
Sbjct: 175 HKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLY 234
Query: 221 NMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISA 280
++++ G VSK VDLAGSERV+KTG GER KE IN L LG VIS+
Sbjct: 235 DLQSGNSGEK------VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISS 288
Query: 281 LGDP---RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANR 337
L D + KS +PYRD+ +T LLKD+LGG+++T MI +SP++ N++E+L++L+YA+R
Sbjct: 289 LADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADR 348
Query: 338 ARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQA 375
A+ I N VN P + I E+ E++ LRE L +A
Sbjct: 349 AKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEA 386
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 247 bits (631), Expect = 5e-65
Identities = 155/398 (38%), Positives = 228/398 (57%), Gaps = 35/398 (8%)
Query: 1 MEEIPVKVAVRIRPL---------LCKEALHNHQVCVRVIP-NSQQVIIGRDRVFTFDFV 50
M + VKVAVR+RP+ C + +Q + P N++Q +VF FD+
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC 60
Query: 51 FG--------KNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASV 102
F K + Q+ V+ + ++ +GYNA +FAYGQTGSGK++++ G
Sbjct: 61 FWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH----- 115
Query: 103 VEGQKGIIPRAIQEIFQSIS--EHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIRE 160
Q G+IPR +F+ IS ++ S F V+VSY+E+Y E +RDLL+ + S + L +RE
Sbjct: 116 -AEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVRE 174
Query: 161 DEKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHK 220
+ + G + V S ++ SL+ GN +R T MNE SSRSHA+F I I Q
Sbjct: 175 HKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLY 234
Query: 221 NMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISA 280
++++ G VSK VDLAGSERV+KTG GER KE IN L LG VIS+
Sbjct: 235 DLQSGNSGEK------VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISS 288
Query: 281 LGDP---RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANR 337
L D + KS +PYRD+ +T LLKD+LGG+++T MI +SP++ N++E+L++L+YA+R
Sbjct: 289 LADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADR 348
Query: 338 ARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQA 375
A+ I N VN P + I E+ E++ LRE L +A
Sbjct: 349 AKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEA 386
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 247 bits (631), Expect = 5e-65
Identities = 155/398 (38%), Positives = 228/398 (57%), Gaps = 35/398 (8%)
Query: 1 MEEIPVKVAVRIRPL---------LCKEALHNHQVCVRVIP-NSQQVIIGRDRVFTFDFV 50
M + VKVAVR+RP+ C + +Q + P N++Q +VF FD+
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC 60
Query: 51 FG--------KNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASV 102
F K + Q+ V+ + ++ +GYNA +FAYGQTGSGK++++ G
Sbjct: 61 FWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH----- 115
Query: 103 VEGQKGIIPRAIQEIFQSIS--EHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIRE 160
Q G+IPR +F+ IS ++ S F V+VSY+E+Y E +RDLL+ + S + L +RE
Sbjct: 116 -AEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVRE 174
Query: 161 DEKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHK 220
+ + G + V S ++ SL+ GN +R T MNE SSRSHA+F I I Q
Sbjct: 175 HKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLY 234
Query: 221 NMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISA 280
++++ G VSK VDLAGSERV+KTG GER KE IN L LG VIS+
Sbjct: 235 DLQSGNSGEK------VSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISS 288
Query: 281 LGDP---RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANR 337
L D + KS +PYRD+ +T LLKD+LGG+++T MI +SP++ N++E+L++L+YA+R
Sbjct: 289 LADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADR 348
Query: 338 ARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQA 375
A+ I N VN P + I E+ E++ LRE L +A
Sbjct: 349 AKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAEA 386
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 244 bits (622), Expect = 5e-64
Identities = 150/400 (37%), Positives = 224/400 (56%), Gaps = 31/400 (7%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRD-----RVFTFDFVFGKNST---- 56
VKVAVR+RP +E + + V + N+ +I + + FTFD+ + +++
Sbjct: 6 VKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTEDP 65
Query: 57 ----QDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPR 112
Q +VY + ++L EGYN +FAYGQTG+GK+YT+ G GQ+GI+P+
Sbjct: 66 QFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQ----EPGQQGIVPQ 121
Query: 113 AIQEIFQSISEHPS--IDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVG 170
+++F +SE+ S + ++V+VSY+E+Y E +RDLL + S L +RE +
Sbjct: 122 LCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPK-SRGSLRVREHPILGPYVQD 180
Query: 171 AKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQ-VHKNMEAAEDGS 229
+ V S ++ L++ GN AR T MNE SSRSHA+FTI Q H + +
Sbjct: 181 LSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEK 240
Query: 230 WYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGD---PRR 286
VSK VDLAGSER +G G R KE IN L LG VISAL D +R
Sbjct: 241 -------VSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKR 293
Query: 287 KSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPT 346
KS IPYRD+ +T LLK++LGG+++T MI +SP+ N++E+L++L+YA+R + IR
Sbjct: 294 KSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAI 353
Query: 347 VNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINRE 386
+N P + I E++ E+ LRE L +Q S + E
Sbjct: 354 INEDPNARLIRELQEEVARLRELLMAQGLSASALEGLKTE 393
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 239 bits (609), Expect = 2e-62
Identities = 274/1045 (26%), Positives = 481/1045 (46%), Gaps = 150/1045 (14%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVII--------GRDRVFTFDFVFGKNSTQ 57
++V VR RP E + V P ++V + + +TFD VFG ++ Q
Sbjct: 19 IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQ 78
Query: 58 DEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVV-----EGQKGIIPR 112
+VY + + P++ +I GYN T+FAYGQTG+GKT+T+ G + + GIIPR
Sbjct: 79 IDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPR 138
Query: 113 AIQEIFQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKD-LHIRED--EKGNTVIV 169
+ +IF+ ++++ + +F+VKVS +E+Y E+L DLL + + + L + +D K +I
Sbjct: 139 TLHQIFEKLTDNGT-EFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIK 197
Query: 170 GAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGS 229
G +E V + EV +LE G A R T T MN +SSRSH++F+++I ++ E
Sbjct: 198 GLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVK 257
Query: 230 WYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSS 289
+ K + VDLAGSE + ++G +R +E+ IN LL LG VI+AL + ++
Sbjct: 258 -------IGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE---RTP 307
Query: 290 HIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNF 349
H+PYR++K+TR+L+DSLGG +T +I +SP+S N +E+L++L+YA+RA+NI NKP VN
Sbjct: 308 HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQ 367
Query: 350 S-PESDRIDEMEFEIKLLREALQS--QQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQG 406
+ I E EI+ L+ L + ++ GV + + R S ++ EEQ+ +L
Sbjct: 368 KLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMS---GKLTVQEEQIVELI- 423
Query: 407 ECLGYQCCVEEAFTFLVDL----------------KDTVRLNEKQQHKLQEWFNMIQE-- 448
E +G VEE + +L T L Q+H + +++E
Sbjct: 424 EKIG---AVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEY 480
Query: 449 VRKAVLTSFRGIGGTAS-----LEEGPQHVTVLQLKRELKKCQCVLAADEVVFNQKELEV 503
+ A+ ++ + AS +EE + V+ L K + KK A D+ +++
Sbjct: 481 ITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKK-----AVDQHNAEAQDIFG 535
Query: 504 KELK---NQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVT 560
K L N ++ ++++ ++ E K L + LS ++ L+ T
Sbjct: 536 KNLNSLFNNMEELIKDGSSKQKAMLEVHKT------------LFGNLLSSSVSALDTITT 583
Query: 561 SSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIF-AG 619
+ G IPE TH+ + ++ S + + L +
Sbjct: 584 VAL------GSLTSIPEN------VSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTD 631
Query: 620 FRTRSQMLLG-------HIEEQDKVL---HCQFSDNSDDEESEGQEKSGTRCRSRSWIQK 669
+ +M+L I Q K + +D +D++ E C + +Q+
Sbjct: 632 LLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQE 691
Query: 670 PDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMREL 729
+++CSLVE + Q +L EDLK SQE L KL N + TE + E
Sbjct: 692 -NTICSLVE-----SQKQCGNL-TEDLKTIKQTHSQE--LCKLMN---LWTERFCALEEK 739
Query: 730 TINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAE----------QAKVELIETQ 779
NI+ ++E I+ +K + + + K D++ Q +L+E
Sbjct: 740 CENIQKPLSSVQENIQ--QKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEES 797
Query: 780 KQLQELENKDLSDVAMKVKLQKEF--RKKMDAAKLRVQVLQKKQQDSKKLASLSIQ-NEK 836
+ + N +L ++ + + + E + + ++ V L +++Q+ L + Q E
Sbjct: 798 VKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCEA 857
Query: 837 RANELEQSVD-----HMKYQKIQLQRKLREENE---KRKQLDAVIKRDQQKIK---EIQL 885
++++ + D H K I L + +E++ + +L+ IK K+ E L
Sbjct: 858 SSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNETIKIGLTKLNCFLEQDL 917
Query: 886 KTGQEEGLKPKAED-LDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEE 944
K G P+ + L L R + +HL LD+ K+ E + + EE
Sbjct: 918 KLDIPTGTTPQRKSYLYPSTLVRTEPR----EHL--LDQLKRKQPELLMMLNCSENNKEE 971
Query: 945 LEADLKKREAIVSK--KEALLQEKS 967
D+ EA++ + +E L QE S
Sbjct: 972 TIPDVDVEEAVLGQYTEEPLSQEPS 996
Score = 48.5 bits (114), Expect = 4e-05
Identities = 89/417 (21%), Positives = 161/417 (38%), Gaps = 34/417 (8%)
Query: 688 KSDLENEDLKIDCLQES-QELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKT 746
KSDL+N+ +++ Q+ QE LQ +K E +T A + E + K L+ + +T
Sbjct: 451 KSDLQNKTQELETTQKHLQETKLQLVK--EEYITSALESTEEKLHDAASK--LLNTVEET 506
Query: 747 GNDAKSVSKQYSLKVTKLEHDAEQAKV---ELIETQKQLQELENKDLSDVAMKVKLQKEF 803
D + + K +H+AE + L ++EL + D + K K E
Sbjct: 507 TKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEEL----IKDGSSKQKAMLEV 562
Query: 804 RKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREEN 863
K + L V + L SL+ E + + Q + + ++ Q E
Sbjct: 563 HKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMI----LKEQSLAAESK 618
Query: 864 EKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDE 923
++L V+K D L + E L P + N + + S+ K+++
Sbjct: 619 TVLQELINVLKTD--------LLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIED 670
Query: 924 QKKWLDEEVEKVLNQRQELEE-----LEADLKK----REAIVSKKEALLQEKSHLENKKL 974
QKK LD + + N EL+E L K+ E + + K+ QE L N
Sbjct: 671 QKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMNLWT 730
Query: 975 RSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKE-KDQLQKR 1033
AL I L+ +++ + +K+ + K + +E ++ Q+
Sbjct: 731 ERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEG 790
Query: 1034 RHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNL 1090
V+E +K+ L+ E + + E+ E+L Y +E + HNL
Sbjct: 791 TKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNL 847
Score = 40.0 bits (92), Expect = 0.016
Identities = 41/211 (19%), Positives = 92/211 (43%), Gaps = 2/211 (0%)
Query: 831 SIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQE 890
+I N+ N+ +K +++R R+ R++ I + ++ +L T QE
Sbjct: 358 NILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKL-TVQE 416
Query: 891 EGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLK 950
E + E + A + + + +D+ +LD+ K L + +++ ++ L+E + L
Sbjct: 417 EQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLV 476
Query: 951 KREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTA 1010
K E I S E+ ++ +K L + + D + ++L+ ++ + + N + Q
Sbjct: 477 KEEYITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLD-RKKAVDQHNAEAQDIFG 535
Query: 1011 EEKTKISEQVEVLQKEKDQLQKRRHNVDEKL 1041
+ + +E L K+ QK V + L
Sbjct: 536 KNLNSLFNNMEELIKDGSSKQKAMLEVHKTL 566
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 237 bits (605), Expect = 5e-62
Identities = 151/400 (37%), Positives = 219/400 (54%), Gaps = 47/400 (11%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVI--------PNSQQVII---------------GRD 42
+KV VR+RP KE V V+ P ++V +D
Sbjct: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
Query: 43 RVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASV 102
F FD VF + STQ EV+ KP++ S + GYN TV AYG TG+GKT+T+ G
Sbjct: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGS----- 126
Query: 103 VEGQKGIIPRAIQEIFQSISEHPSIDF-NVKVSYIEVYKEDLRDLLELETSMKDLHIRED 161
+ G++ + +++ + E + VSY+EVY E +RDLL + L +RED
Sbjct: 127 -ADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL---VNSGPLAVRED 182
Query: 162 EKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKN 221
+ V+ G +S+ E++ LL+ GN R T MN SSRSHA+F I + Q K
Sbjct: 183 TQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKT 242
Query: 222 MEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISAL 281
++ ++K +DLAGSER + +G G RF E IN LLALGNVI+AL
Sbjct: 243 ASINQNVR-------IAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINAL 295
Query: 282 GDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNI 341
D +RK+ HIPYR++K+TRLLKDSLGG+ +T+MI VSPSS +D++ N+LKYANRA++I
Sbjct: 296 ADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 355
Query: 342 RNKPTVNFSPESDRI-------DEMEFEIKLLREALQSQQ 374
++ N ++ I +E + EI LL+E L++ +
Sbjct: 356 KSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYE 395
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 236 bits (602), Expect = 1e-61
Identities = 152/419 (36%), Positives = 225/419 (53%), Gaps = 38/419 (9%)
Query: 8 VAVRIRPLLCKEALHNHQVCVRVIPNSQQVII--------------GRDRVFTFDFVFGK 53
VA+R+RP+ E + + V++ R++ + FD F
Sbjct: 14 VALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDF 73
Query: 54 NSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRA 113
+TQ+ VY K L+ +I GYNATVFAYG TG GKTYT+ G + + GI +
Sbjct: 74 TATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLG------TDQEPGIYVQT 127
Query: 114 IQEIFQSISEHPS-IDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAK 172
+ ++F++I E + +++ V +SY+E+Y E +RDLL S+ L +RED KG + G
Sbjct: 128 LNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLN--PSLGYLELREDSKGVIQVAGIT 185
Query: 173 ECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQ---VHKNMEAAEDGS 229
E +A E+M LL GN R T N+ SSRSHA+ +++ Q V ++ G
Sbjct: 186 EVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQG- 244
Query: 230 WYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSS 289
+ +DLAGSER ++T N G+R KE IN LLALGN I+AL D + +
Sbjct: 245 ---------RLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSD-KGSNK 294
Query: 290 HIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNF 349
+I YRD+K+TRLLKDSLGG+++TVMI +SP+SS F+ES N+L YA RA+NI+ + N
Sbjct: 295 YINYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNL 354
Query: 350 SPESDRIDEMEFEIKLLREALQSQQAGV-SQTTQINREGSPDTNRIHSLEEQVAQLQGE 407
S I + I LR +Q + + QT + G D I ++ +V G+
Sbjct: 355 LNVSYHIAQYTSIIADLRGEIQRLKRKIDEQTGRGQARGRQDRGDIRHIQAEVQLHSGQ 413
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 233 bits (594), Expect = 1e-60
Identities = 161/515 (31%), Positives = 269/515 (52%), Gaps = 43/515 (8%)
Query: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRD-----RVFTFDFVFGKNST---- 56
VKVAVR+RP +E + + +++ ++ ++ + + F+FD+ + +++
Sbjct: 6 VKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDI 65
Query: 57 ----QDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPR 112
Q +VY + ++ EGYN +FAYGQTG+GK+YT+ G + Q+GIIP+
Sbjct: 66 NYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQ----EKDQQGIIPQ 121
Query: 113 AIQEIFQSISE--HPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVG 170
+++F I++ + ++ ++V+VSY+E+Y E +RDLL + +L +RE +
Sbjct: 122 LCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNK-GNLRVREHPLLGPYVED 180
Query: 171 AKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSW 230
+ V S ++ L++ GN AR T MNE SSRSHA+F I Q + E
Sbjct: 181 LSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETN----- 235
Query: 231 YSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGD------- 283
VSK VDLAGSER TG G R KE IN L LG VISAL +
Sbjct: 236 -ITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNK 294
Query: 284 --PRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNI 341
++K+ IPYRD+ +T LL+++LGG+++T M+ +SP+ N+DE+L++L+YA+RA+ I
Sbjct: 295 NKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQI 354
Query: 342 RNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQV 401
R +N P + I E++ E+ LR+ L +Q G G ++ + +L +
Sbjct: 355 RCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDMTNALVGMSPSSSLSALSSRA 414
Query: 402 AQLQG--ECLGYQCCVEEAFTFLVDLKDTV-RLNEKQQHKLQEWFNMIQEVRKAVL---- 454
A + E + + EEA L + + + LNE + KL+ I+ R+A+L
Sbjct: 415 ASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRR-TEAIRMEREALLAEMG 473
Query: 455 TSFRGIGGTASLEEGPQHVTVLQLKRELKKCQCVL 489
+ R GGT + + ++ L + +C+L
Sbjct: 474 VAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLL 508
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 221 bits (563), Expect = 4e-57
Identities = 144/423 (34%), Positives = 228/423 (53%), Gaps = 28/423 (6%)
Query: 1 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVI--------PNSQQV--IIGRDRVFTFDFV 50
+E V VAVR+RP +E + V + P+++QV I ++FD
Sbjct: 354 VENSQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDEC 413
Query: 51 FGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGII 110
++Q VY PL+ EG+N +FAYGQTGSGK+YT+ G + GII
Sbjct: 414 HPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMG------FSEEPGII 467
Query: 111 PRAIQEIFQSISEHPS--IDFNVKVSYIEVYKEDLRDLL----ELETSMKDLHIREDEKG 164
PR +++F ++ + + +++++S+ EVY E + DLL E + L +RE
Sbjct: 468 PRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVY 527
Query: 165 NTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEA 224
+ V S ++ S LE+GN R T T MN+ SSRSH++FT+ + Q
Sbjct: 528 GPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVE 587
Query: 225 AEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDP 284
E+ I S+ + +DLAGSER + G+R KE + IN LL LG VISAL +
Sbjct: 588 GEEHD----HRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQ 643
Query: 285 -RRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRN 343
++S IPYR++ +T LLK+SLGG++KT MI +SP++SN +E+L++L+YAN+AR I N
Sbjct: 644 ANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVN 703
Query: 344 KPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTN-RIHSLEEQVA 402
VN + I E++ EI L+ A ++ + + ++ R+ ++H E +A
Sbjct: 704 IAKVNEDMNAKLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMA 763
Query: 403 QLQ 405
++Q
Sbjct: 764 EMQ 766
Score = 45.8 bits (107), Expect = 3e-04
Identities = 47/191 (24%), Positives = 90/191 (47%), Gaps = 22/191 (11%)
Query: 865 KRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSI-----DHLQ 919
+R QL+A IK Q K KE ++ Q A+++ L +K ++ S L+
Sbjct: 935 QRSQLEAEIKEAQLKAKEEMMQGIQI------AKEMAQQELSSQKAAYESKIKALEAELR 988
Query: 920 KLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEA---LLQEKSHLENKKLRS 976
+ ++KK + +K ++ +ELE+ + L++ E V+KK L K LE+ +R
Sbjct: 989 EESQRKKMQEINNQKANHKIEELEKAKQHLEQ-EIYVNKKRLEMETLATKQALEDHSIRH 1047
Query: 977 S---QALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVE----VLQKEKDQ 1029
+ +AL T+ KI+ + +L+Q + ++ T K+S ++ + K K
Sbjct: 1048 ARILEALETEKQKIAKEVQILQQNRNNRDKTFTVQTTWSSMKLSMMIQEANAISSKLKTY 1107
Query: 1030 LQKRRHNVDEK 1040
RH++ +K
Sbjct: 1108 YVFGRHDISDK 1118
Score = 32.3 bits (72), Expect = 3.3
Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 26/145 (17%)
Query: 767 DAEQAKVELIETQKQLQELENKDLSDVAM----------KVKLQKEFRKKMDAAKLRVQV 816
D E AK EL+ Q+ E E K+ A K Q+E + A + +++
Sbjct: 923 DFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKA 982
Query: 817 LQKKQQDSKKLASLSIQNEKRAN----ELEQSVDHMKYQKIQLQRKLREENEKRKQ---- 868
L+ + ++ + + N ++AN ELE++ H++ + +++L E KQ
Sbjct: 983 LEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALED 1042
Query: 869 --------LDAVIKRDQQKIKEIQL 885
L+A+ Q+ KE+Q+
Sbjct: 1043 HSIRHARILEALETEKQKIAKEVQI 1067
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,938,018
Number of Sequences: 37866
Number of extensions: 2343800
Number of successful extensions: 20754
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 333
Number of HSP's successfully gapped in prelim test: 1275
Number of HSP's that attempted gapping in prelim test: 9488
Number of HSP's gapped (non-prelim): 6167
length of query: 1401
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1286
effective length of database: 13,892,928
effective search space: 17866305408
effective search space used: 17866305408
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.