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Search of human proteins with 30578412
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30578412 potassium channel tetramerisation domain containing
13 [Homo sapiens]
(329 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30578412 potassium channel tetramerisation domain containing ... 664 0.0
gi|13994353 potassium channel tetramerisation domain containing ... 431 e-121
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo... 416 e-116
gi|71143104 potassium channel tetramerisation domain containing ... 86 6e-17
gi|23308551 potassium channel tetramerisation domain containing ... 78 9e-15
gi|146198864 potassium channel tetramerisation domain containing... 67 2e-11
gi|142356950 potassium channel tetramerisation domain containing... 64 1e-10
gi|189571693 potassium channel tetramerisation domain containing... 64 2e-10
gi|189571691 potassium channel tetramerisation domain containing... 64 2e-10
gi|194018443 potassium channel tetramerisation domain containing... 60 2e-09
gi|194018441 potassium channel tetramerisation domain containing... 60 2e-09
gi|194018439 potassium channel tetramerisation domain containing... 60 2e-09
gi|169234778 potassium channel tetramerisation domain containing... 59 5e-09
gi|38198663 potassium channel tetramerisation domain containing ... 59 8e-09
gi|39753959 potassium channel tetramerisation domain containing ... 57 3e-08
gi|55926200 potassium channel tetramerisation domain containing ... 55 7e-08
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens] 55 9e-08
gi|53829365 potassium channel tetramerisation domain containing ... 55 9e-08
gi|45387953 potassium channel tetramerization domain containing ... 54 1e-07
gi|9506651 potassium channel tetramerisation domain containing 5... 52 9e-07
gi|169184031 PREDICTED: similar to potassium channel tetramerisa... 51 2e-06
gi|169179790 PREDICTED: similar to potassium channel tetramerisa... 51 2e-06
gi|169180181 PREDICTED: similar to potassium channel tetramerisa... 51 2e-06
gi|218505694 potassium channel tetramerisation domain containing... 51 2e-06
gi|209969708 potassium channel tetramerisation domain containing... 51 2e-06
gi|40217617 potassium channel tetramerisation domain containing ... 51 2e-06
gi|19923973 potassium channel tetramerisation domain containing ... 49 5e-06
gi|46255026 potassium channel tetramerisation domain containing ... 49 6e-06
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens] 48 1e-05
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens] 48 1e-05
>gi|30578412 potassium channel tetramerisation domain containing 13
[Homo sapiens]
Length = 329
Score = 664 bits (1713), Expect = 0.0
Identities = 329/329 (100%), Positives = 329/329 (100%)
Query: 1 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT 60
MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT
Sbjct: 1 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT 60
Query: 61 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE 120
GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE
Sbjct: 61 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE 120
Query: 121 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN 180
ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN
Sbjct: 121 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN 180
Query: 181 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS 240
KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS
Sbjct: 181 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS 240
Query: 241 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN 300
IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN
Sbjct: 241 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN 300
Query: 301 REHRVRRIHVRRHITHDERPHGQQIVFKD 329
REHRVRRIHVRRHITHDERPHGQQIVFKD
Sbjct: 301 REHRVRRIHVRRHITHDERPHGQQIVFKD 329
>gi|13994353 potassium channel tetramerisation domain containing 10
[Homo sapiens]
Length = 313
Score = 431 bits (1109), Expect = e-121
Identities = 213/293 (72%), Positives = 252/293 (86%), Gaps = 6/293 (2%)
Query: 34 KPLTPNSKYVKLNVGGSLHYTTLRTLTGQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHF 93
K +P+SKYVKLNVGG+L+YTT++TLT QDTMLKAMFSGR+EVLTD+ GW+LIDR G+HF
Sbjct: 25 KGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHF 84
Query: 94 GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMV 153
GTILNYLRDG+VPLPES RE+ ELL EA+YYLVQGL+E+CQ ALQ K +T P C +P++
Sbjct: 85 GTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNK-DTYEPFCKVPVI 143
Query: 154 TSPREEQQLLASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFL 213
TS +EEQ+L+A+++KP VKLL+NRSNNKYSYTS SDDN+LKNIELFDKL+LRF+GR+LF+
Sbjct: 144 TSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFI 203
Query: 214 KDVLGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETP- 272
KDV+GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARI+EETLNIL+YE
Sbjct: 204 KDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 263
Query: 273 -RGPDPALLEATGGAAGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQ 324
RGPD ALLEATGGAAG ++E R RVRRIH++R D+R H Q
Sbjct: 264 GRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRIHIKR---PDDRAHLHQ 313
>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
sapiens]
Length = 316
Score = 416 bits (1070), Expect = e-116
Identities = 203/322 (63%), Positives = 252/322 (78%), Gaps = 14/322 (4%)
Query: 8 PAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQDTMLK 67
PA+ A P L K GL +KYV+LNVGGSL+YTT+R LT DTMLK
Sbjct: 9 PASGAKPKLSGFKGGGL--------------GNKYVQLNVGGSLYYTTVRALTRHDTMLK 54
Query: 68 AMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQ 127
AMFSGR+EVLTD GW+LIDR G+HFGTILNYLRD ++ LP++ +E+ EL+ EA+YYL+Q
Sbjct: 55 AMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQ 114
Query: 128 GLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKYSYTST 187
GL+ CQ ALQ K+++ P+C IP++TS +EE++L+ S++KPVVKLL+NRSNNKYSYTS
Sbjct: 115 GLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSN 174
Query: 188 SDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSIVYATEK 247
SDD+LLKNIELFDKL+LRF+GR+LF+KDV+GDEICCWSFYGQGRK+AEVCCTSIVYATEK
Sbjct: 175 SDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEK 234
Query: 248 KQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEENREHRVRR 307
KQTKVEFPEARI+EETLN+L+YETPR PD +LLEAT + E+ RVRR
Sbjct: 235 KQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEETFELRDRVRR 294
Query: 308 IHVRRHITHDERPHGQQIVFKD 329
IHV+R+ T+D+R G Q +D
Sbjct: 295 IHVKRYSTYDDRQLGHQSTHRD 316
>gi|71143104 potassium channel tetramerisation domain containing 21
[Homo sapiens]
Length = 260
Score = 85.5 bits (210), Expect = 6e-17
Identities = 67/174 (38%), Positives = 90/174 (51%), Gaps = 18/174 (10%)
Query: 43 VKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLR 101
+ LNVGG L+ T+L TLT D+ML AMFSG++ D+ G IDR G+ F ILN+LR
Sbjct: 5 ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
Query: 102 DGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQ 161
+ LPE +E+G L EA +Y VQ LIE ALQ+K L S E+
Sbjct: 65 TSHLDLPEDFQEMGLLRREADFYQVQPLIE----ALQEKEVEL----------SKAEKNA 110
Query: 162 LLASTSKPVVKLLH---NRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLF 212
+L T V+ +H + YS +S+S + NI L L+ G LF
Sbjct: 111 MLNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLF 164
>gi|23308551 potassium channel tetramerisation domain containing 7
[Homo sapiens]
Length = 289
Score = 78.2 bits (191), Expect = 9e-15
Identities = 51/122 (41%), Positives = 68/122 (55%), Gaps = 10/122 (8%)
Query: 16 LEAPKPSGLEPGPAAYGLKPLTPNS--KYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSG 72
LE P+ + G A PL P + V LN+GG+ T L TL +DTML AMFSG
Sbjct: 28 LEPATPTATQAGHAL----PLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSG 83
Query: 73 RVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIED 132
R + TD+ G IDR G HFG +LN+LR G +P E R + + EA+YY + L+E
Sbjct: 84 RHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYK---EAQYYAIGPLLEQ 140
Query: 133 CQ 134
+
Sbjct: 141 LE 142
>gi|146198864 potassium channel tetramerisation domain containing 4
[Homo sapiens]
Length = 259
Score = 67.4 bits (163), Expect = 2e-11
Identities = 42/108 (38%), Positives = 64/108 (59%), Gaps = 3/108 (2%)
Query: 40 SKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILN 98
S + LNVGG L+ T +TLT DT L+ + +G++ DA G IDR G F +LN
Sbjct: 32 STLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLN 91
Query: 99 YLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSP 146
+LR+G + LPE RE L EA ++ ++GL E ++ + ++E L+P
Sbjct: 92 FLRNGELLLPEGFRENQLLAQEAEFFQLKGLAE--EVKSRWEKEQLTP 137
>gi|142356950 potassium channel tetramerisation domain containing 14
[Homo sapiens]
Length = 255
Score = 64.3 bits (155), Expect = 1e-10
Identities = 44/119 (36%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 15 SLEAPKPSGLEPGPAAYGLKPLTPN-SKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSG 72
++E P P +P P S V+LNVGG H TTL TL + L MFS
Sbjct: 6 AVERPVGRMTSQTPLPQSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSS 65
Query: 73 RVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIE 131
+ TDA G IDR +F IL+YLR G VP T+ + E+ EA++Y ++ L++
Sbjct: 66 LAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVP----TQHIPEVYREAQFYEIKPLVK 120
>gi|189571693 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 63.5 bits (153), Expect = 2e-10
Identities = 51/142 (35%), Positives = 65/142 (45%), Gaps = 23/142 (16%)
Query: 43 VKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLR 101
V LNVGG L+ T+L TLT D+ML AMF G D G IDR G F +LN+LR
Sbjct: 14 VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
Query: 102 DGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQ 161
+ LP +E L EA +Y ++ LI+ P L PM
Sbjct: 74 TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLN----------DPKPLYPM--------- 114
Query: 162 LLASTSKPVVKLLHNRSNNKYS 183
T + VV+L R +KYS
Sbjct: 115 ---DTFEEVVELSSTRKLSKYS 133
>gi|189571691 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 63.5 bits (153), Expect = 2e-10
Identities = 51/142 (35%), Positives = 65/142 (45%), Gaps = 23/142 (16%)
Query: 43 VKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLR 101
V LNVGG L+ T+L TLT D+ML AMF G D G IDR G F +LN+LR
Sbjct: 14 VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
Query: 102 DGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQ 161
+ LP +E L EA +Y ++ LI+ P L PM
Sbjct: 74 TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLN----------DPKPLYPM--------- 114
Query: 162 LLASTSKPVVKLLHNRSNNKYS 183
T + VV+L R +KYS
Sbjct: 115 ---DTFEEVVELSSTRKLSKYS 133
>gi|194018443 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/142 (29%), Positives = 78/142 (54%), Gaps = 6/142 (4%)
Query: 36 LTPNSKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDA-GGWVLIDRSGRHF 93
LT ++ V ++VGG ++ ++L TLT D+ + +F+G ++ D+ IDR G F
Sbjct: 51 LTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIF 110
Query: 94 GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLI---EDCQLALQQKRETLSPLCLI 150
+L++LR + LP+ ++ L EARYY +Q ++ E Q +Q+R + + CL+
Sbjct: 111 RYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLV 170
Query: 151 PMVTSPREEQQLLASTSKPVVK 172
VT P +++ S K +++
Sbjct: 171 VRVT-PDLGERIALSGEKALIE 191
>gi|194018441 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/142 (29%), Positives = 78/142 (54%), Gaps = 6/142 (4%)
Query: 36 LTPNSKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDA-GGWVLIDRSGRHF 93
LT ++ V ++VGG ++ ++L TLT D+ + +F+G ++ D+ IDR G F
Sbjct: 51 LTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIF 110
Query: 94 GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLI---EDCQLALQQKRETLSPLCLI 150
+L++LR + LP+ ++ L EARYY +Q ++ E Q +Q+R + + CL+
Sbjct: 111 RYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLV 170
Query: 151 PMVTSPREEQQLLASTSKPVVK 172
VT P +++ S K +++
Sbjct: 171 VRVT-PDLGERIALSGEKALIE 191
>gi|194018439 potassium channel tetramerisation domain containing 15
isoform 1 [Homo sapiens]
Length = 234
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/142 (29%), Positives = 78/142 (54%), Gaps = 6/142 (4%)
Query: 36 LTPNSKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDA-GGWVLIDRSGRHF 93
LT ++ V ++VGG ++ ++L TLT D+ + +F+G ++ D+ IDR G F
Sbjct: 51 LTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIF 110
Query: 94 GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLI---EDCQLALQQKRETLSPLCLI 150
+L++LR + LP+ ++ L EARYY +Q ++ E Q +Q+R + + CL+
Sbjct: 111 RYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLV 170
Query: 151 PMVTSPREEQQLLASTSKPVVK 172
VT P +++ S K +++
Sbjct: 171 VRVT-PDLGERIALSGEKALIE 191
>gi|169234778 potassium channel tetramerisation domain containing 17
[Homo sapiens]
Length = 297
Score = 59.3 bits (142), Expect = 5e-09
Identities = 50/161 (31%), Positives = 81/161 (50%), Gaps = 11/161 (6%)
Query: 16 LEAPKPS-----GLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAM 69
++ P+P+ G PA G + K+V+LNVGG++ TT +TL Q + L +
Sbjct: 1 MQTPRPAMRMEAGEAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRL 60
Query: 70 FSGR-VEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQG 128
G ++ D G LIDR +FG ILN+LR G + L + E G +L EA +Y +
Sbjct: 61 CQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEG-VLEEAEFYNIGP 119
Query: 129 LIEDCQLALQQKRETLS---PLCLIPMVTSPREEQQLLAST 166
LI + +++K T++ P + ++ EE + ST
Sbjct: 120 LIRIIKDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQMVST 160
>gi|38198663 potassium channel tetramerisation domain containing 8
[Homo sapiens]
Length = 473
Score = 58.5 bits (140), Expect = 8e-09
Identities = 48/141 (34%), Positives = 68/141 (48%), Gaps = 25/141 (17%)
Query: 1 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT 60
M + +S P A+AA + PGP A +P + V+LNVGG ++ T TL
Sbjct: 19 MVSSSSSPGASAAAA----------PGPCAP-----SPFPEVVELNVGGQVYVTKHSTLL 63
Query: 61 G-QDTMLKAMFSG---------RVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPES 110
D+ L +MFS R E+ D+ IDR G F +L+YLRD + LPE
Sbjct: 64 SVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEH 123
Query: 111 TRELGELLGEARYYLVQGLIE 131
E LL EA Y+ + L++
Sbjct: 124 FPEKERLLREAEYFQLTDLVK 144
>gi|39753959 potassium channel tetramerisation domain containing 9
[Homo sapiens]
Length = 389
Score = 56.6 bits (135), Expect = 3e-08
Identities = 44/115 (38%), Positives = 63/115 (54%), Gaps = 7/115 (6%)
Query: 39 NSKYVKLNVGGSLHYTTLRTLTGQ--DTMLKAMFS--GRVEVLTDAGGWVLIDRSGRHFG 94
++ ++ LNVGG TT TL + D+ML MF G D G LIDRS +F
Sbjct: 87 HTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFE 146
Query: 95 TILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQ--QKRETLSPL 147
ILNYLR G + + + LG +L EAR++ + LIE ++A++ Q E SP+
Sbjct: 147 PILNYLRHGQLIVNDGINLLG-VLEEARFFGIDSLIEHLEVAIKNSQPPEDHSPI 200
>gi|55926200 potassium channel tetramerisation domain containing 16
[Homo sapiens]
Length = 428
Score = 55.5 bits (132), Expect = 7e-08
Identities = 39/101 (38%), Positives = 54/101 (53%), Gaps = 7/101 (6%)
Query: 38 PNS--KYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAG----GWVLIDRSG 90
PNS + V+LNVGG +++T TL ++L MFS + + D G IDR G
Sbjct: 20 PNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDG 79
Query: 91 RHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIE 131
F IL+YLRD V LP+ E G L EA Y+ + L++
Sbjct: 80 FLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 120
>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
Length = 707
Score = 55.1 bits (131), Expect = 9e-08
Identities = 39/116 (33%), Positives = 57/116 (49%), Gaps = 3/116 (2%)
Query: 29 AAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLID 87
AA G+ P + + LNVGG T+ +TLT D+ ++ SGR+ L D G + ID
Sbjct: 7 AAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFID 66
Query: 88 RSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRET 143
R F ILN+LR + P LL EA++Y + L+ QL + R +
Sbjct: 67 RDPTVFAPILNFLRTKELD-PRGVHG-SSLLHEAQFYGLTPLVRRLQLREELDRSS 120
>gi|53829365 potassium channel tetramerisation domain containing 2
[Homo sapiens]
Length = 263
Score = 55.1 bits (131), Expect = 9e-08
Identities = 48/165 (29%), Positives = 78/165 (47%), Gaps = 23/165 (13%)
Query: 18 APKPSGLEPG----PAAYGLKPLTPN------------SKYVKLNVGGSLHYTTLRTLTG 61
+P+P+G P PAA +PL P +++V+LNVGG+ TT +TL
Sbjct: 33 SPRPAGPTPRGHGRPAAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGR 92
Query: 62 QDTM----LKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGEL 117
+ L ++ D G LIDR +FG ILNYLR G + + + E G +
Sbjct: 93 EPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEG-V 151
Query: 118 LGEARYYLVQGLIEDCQLALQ--QKRETLSPLCLIPMVTSPREEQ 160
L EA +Y + L+ + ++ + R + P+ + V +EE+
Sbjct: 152 LEEAEFYNIASLVRLVKERIRDNENRTSQGPVKHVYRVLQCQEEE 196
>gi|45387953 potassium channel tetramerization domain containing 18
[Homo sapiens]
Length = 426
Score = 54.3 bits (129), Expect = 1e-07
Identities = 58/201 (28%), Positives = 93/201 (46%), Gaps = 28/201 (13%)
Query: 43 VKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLR 101
++LNVGG ++ +L +D+ML +MFSGR + TD G +IDR GR F +L+YL
Sbjct: 14 LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYLH 73
Query: 102 DGSVPLPESTRELGELLGEARYYLVQGLIEDCQLA--LQQKRETLSPLCLIPM---VTSP 156
G V +P + L EA Y+ G+ L+ L + ET S I + +T
Sbjct: 74 -GEVQIPTDEQTRIALQEEADYF---GIPYPYSLSDHLANEMETYSLRSNIELKKALTDF 129
Query: 157 REEQQLLASTSKPVVKLLH----------NRSNNKYSYTSTSDDNLLKNIELFDKLALRF 206
+ L+ +KP V +LH +R Y+ + D + K +L R
Sbjct: 130 CDSYGLVC--NKPTVWVLHYLNTSGASCESRIIGVYATKTDGTDAIEK------QLGGRI 181
Query: 207 HGRLLFLKDVLGDEICCWSFY 227
H + +F ++ + WS+Y
Sbjct: 182 HSKGIFKREAGNNVQYIWSYY 202
>gi|9506651 potassium channel tetramerisation domain containing 5
[Homo sapiens]
Length = 234
Score = 51.6 bits (122), Expect = 9e-07
Identities = 40/116 (34%), Positives = 61/116 (52%), Gaps = 7/116 (6%)
Query: 40 SKYVKLNVGGSLHYTTLRTLTGQD-TMLKAMFSGRVEVLTDAG--GWVLIDRSGRHFGTI 96
SK+V+LNVGG+ TT +TL + L + ++ +D G LIDR +FG +
Sbjct: 43 SKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPV 102
Query: 97 LNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPM 152
LNYLR G + + + E G +L EA +Y + LI +L + RE S +P+
Sbjct: 103 LNYLRHGKLVINKDLAEEG-VLEEAEFYNITSLI---KLVKDKIRERDSKTSQVPV 154
>gi|169184031 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 50.8 bits (120), Expect = 2e-06
Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 5/107 (4%)
Query: 39 NSKYVKLNVGGSLHYTTLRTLTGQ--DTMLKAMFS--GRVEVLTDAGGWVLIDRSGRHFG 94
++ ++ L+VGG TT TL + D ML MF G D G LID+S +F
Sbjct: 87 HTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFE 146
Query: 95 TILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKR 141
ILNYLR G + + + LG +L EAR++ + LIE ++A++ +
Sbjct: 147 PILNYLRHGQLIVNDGIDLLG-VLEEARFFGIDSLIEHLKVAIKNSQ 192
>gi|169179790 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 50.8 bits (120), Expect = 2e-06
Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 5/107 (4%)
Query: 39 NSKYVKLNVGGSLHYTTLRTLTGQ--DTMLKAMFS--GRVEVLTDAGGWVLIDRSGRHFG 94
++ ++ L+VGG TT TL + D ML MF G D G LID+S +F
Sbjct: 87 HTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFE 146
Query: 95 TILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKR 141
ILNYLR G + + + LG +L EAR++ + LIE ++A++ +
Sbjct: 147 PILNYLRHGQLIVNDGIDLLG-VLEEARFFGIDSLIEHLKVAIKNSQ 192
>gi|169180181 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 50.8 bits (120), Expect = 2e-06
Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 5/107 (4%)
Query: 39 NSKYVKLNVGGSLHYTTLRTLTGQ--DTMLKAMFS--GRVEVLTDAGGWVLIDRSGRHFG 94
++ ++ L+VGG TT TL + D ML MF G D G LID+S +F
Sbjct: 87 HTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFE 146
Query: 95 TILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKR 141
ILNYLR G + + + LG +L EAR++ + LIE ++A++ +
Sbjct: 147 PILNYLRHGQLIVNDGIDLLG-VLEEARFFGIDSLIEHLKVAIKNSQ 192
>gi|218505694 potassium channel tetramerisation domain containing 1
isoform b [Homo sapiens]
Length = 865
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/110 (30%), Positives = 63/110 (57%), Gaps = 3/110 (2%)
Query: 36 LTPNSKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDA-GGWVLIDRSGRHF 93
LT ++ V ++VGG ++ ++L TLT ++ + +F G ++ D+ IDR G+ F
Sbjct: 633 LTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMF 692
Query: 94 GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRET 143
ILN+LR + +P+ ++ L EA+Y+ +Q ++ + + +Q RET
Sbjct: 693 RYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRET 741
>gi|209969708 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/110 (30%), Positives = 63/110 (57%), Gaps = 3/110 (2%)
Query: 36 LTPNSKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDA-GGWVLIDRSGRHF 93
LT ++ V ++VGG ++ ++L TLT ++ + +F G ++ D+ IDR G+ F
Sbjct: 25 LTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMF 84
Query: 94 GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRET 143
ILN+LR + +P+ ++ L EA+Y+ +Q ++ + + +Q RET
Sbjct: 85 RYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRET 133
>gi|40217617 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 50.8 bits (120), Expect = 2e-06
Identities = 33/110 (30%), Positives = 63/110 (57%), Gaps = 3/110 (2%)
Query: 36 LTPNSKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDA-GGWVLIDRSGRHF 93
LT ++ V ++VGG ++ ++L TLT ++ + +F G ++ D+ IDR G+ F
Sbjct: 25 LTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMF 84
Query: 94 GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRET 143
ILN+LR + +P+ ++ L EA+Y+ +Q ++ + + +Q RET
Sbjct: 85 RYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRET 133
>gi|19923973 potassium channel tetramerisation domain containing 12
[Homo sapiens]
Length = 325
Score = 49.3 bits (116), Expect = 5e-06
Identities = 36/99 (36%), Positives = 54/99 (54%), Gaps = 5/99 (5%)
Query: 35 PLTPNSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRV--EVLTDAGGWVLIDRSGR 91
PL P+ V+LNVGG ++ T T+ D++L MF+ + E+ D+ G +DR G
Sbjct: 30 PLFPD--IVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGF 87
Query: 92 HFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLI 130
F IL+YLRD + LP+ E L EA Y+ + L+
Sbjct: 88 LFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELV 126
>gi|46255026 potassium channel tetramerisation domain containing 3
[Homo sapiens]
Length = 815
Score = 48.9 bits (115), Expect = 6e-06
Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
Query: 39 NSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTIL 97
+ + V+LNVGG+ T+ +TL D+ ++ SGR+ L D G + IDR F IL
Sbjct: 16 SGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPIL 75
Query: 98 NYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRET 143
N+LR + L + + L EA +Y + L+ L + +R +
Sbjct: 76 NFLRTKELDLRGVS--INVLRHEAEFYGITPLVRRLLLCEELERSS 119
>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
Length = 229
Score = 48.1 bits (113), Expect = 1e-05
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 39 NSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTIL 97
+ + V LNVGG + T T+ + L M GR + GG + +DR G F IL
Sbjct: 3 SQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFIL 62
Query: 98 NYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETL 144
++LR + LP + L EA +Y ++ L++ L Q R L
Sbjct: 63 DFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPAL 109
>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
Length = 272
Score = 48.1 bits (113), Expect = 1e-05
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 39 NSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTIL 97
+ + V LNVGG + T T+ + L M GR + GG + +DR G F IL
Sbjct: 3 SQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFIL 62
Query: 98 NYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETL 144
++LR + LP + L EA +Y ++ L++ L Q R L
Sbjct: 63 DFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPAL 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,953,400
Number of Sequences: 37866
Number of extensions: 693796
Number of successful extensions: 4131
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 4012
Number of HSP's gapped (non-prelim): 122
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.