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Search of human proteins with 30520377
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30520377 CUB and zona pellucida-like domains 1 [Homo
sapiens]
(607 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens] 1224 0.0
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 296 3e-80
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 296 3e-80
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 296 3e-80
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 296 3e-80
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 296 3e-80
gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] 108 1e-23
gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens] 108 1e-23
gi|126091152 cubilin [Homo sapiens] 106 5e-23
gi|22547221 tolloid-like 1 [Homo sapiens] 103 5e-22
gi|6912724 tolloid-like 2 [Homo sapiens] 102 1e-21
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 99 9e-21
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 98 2e-20
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 98 2e-20
gi|66864913 neuropilin 1 isoform c [Homo sapiens] 96 1e-19
gi|66912178 neuropilin 1 isoform b [Homo sapiens] 96 1e-19
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 96 1e-19
gi|72384339 CUB domain containing protein 2 [Homo sapiens] 96 1e-19
gi|13899255 membrane frizzled-related protein [Homo sapiens] 93 6e-19
gi|4508045 zona pellucida glycoprotein 2 preproprotein [Homo sap... 92 1e-18
gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens] 91 2e-18
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 91 4e-18
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 91 4e-18
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 91 4e-18
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 91 4e-18
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 91 4e-18
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 91 4e-18
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 85 2e-16
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 85 2e-16
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 85 2e-16
>gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]
Length = 607
Score = 1224 bits (3168), Expect = 0.0
Identities = 607/607 (100%), Positives = 607/607 (100%)
Query: 1 MELVRRLMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPSENCTW 60
MELVRRLMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPSENCTW
Sbjct: 1 MELVRRLMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPSENCTW 60
Query: 61 TIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSS 120
TIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSS
Sbjct: 61 TIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSS 120
Query: 121 STLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYC 180
STLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYC
Sbjct: 121 STLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYC 180
Query: 181 VWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSS 240
VWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSS
Sbjct: 181 VWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSS 240
Query: 241 NSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNN 300
NSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNN
Sbjct: 241 NSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNN 300
Query: 301 LQLKDPTCRPKLSNVVEFSVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQ 360
LQLKDPTCRPKLSNVVEFSVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQ
Sbjct: 301 LQLKDPTCRPKLSNVVEFSVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQ 360
Query: 361 IIVKCEMGHNSTVEIIYITEDDVIQSQNALGKYNTSMALFESNSFEKTILESPYYVDLNQ 420
IIVKCEMGHNSTVEIIYITEDDVIQSQNALGKYNTSMALFESNSFEKTILESPYYVDLNQ
Sbjct: 361 IIVKCEMGHNSTVEIIYITEDDVIQSQNALGKYNTSMALFESNSFEKTILESPYYVDLNQ 420
Query: 421 TLFVQVSLHTSDPNLVVFLDTCRASPTSDFASPTYDLIKSGCSRDETCKVYPLFGHYGRF 480
TLFVQVSLHTSDPNLVVFLDTCRASPTSDFASPTYDLIKSGCSRDETCKVYPLFGHYGRF
Sbjct: 421 TLFVQVSLHTSDPNLVVFLDTCRASPTSDFASPTYDLIKSGCSRDETCKVYPLFGHYGRF 480
Query: 481 QFNAFKFLRSMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRL 540
QFNAFKFLRSMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRL
Sbjct: 481 QFNAFKFLRSMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRL 540
Query: 541 KRDRSASGNSGFQHETHAEETPNQPFNSVHLFSFMVLALNVVTVATITVRHFVNQRADYK 600
KRDRSASGNSGFQHETHAEETPNQPFNSVHLFSFMVLALNVVTVATITVRHFVNQRADYK
Sbjct: 541 KRDRSASGNSGFQHETHAEETPNQPFNSVHLFSFMVLALNVVTVATITVRHFVNQRADYK 600
Query: 601 YQKLQNY 607
YQKLQNY
Sbjct: 601 YQKLQNY 607
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 296 bits (759), Expect = 3e-80
Identities = 160/412 (38%), Positives = 255/412 (61%), Gaps = 24/412 (5%)
Query: 148 NISIPN----CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEI 203
NI+ PN CGG+L G F+SP YP +P A CVW I+V+ +Y++ + F+++ LE
Sbjct: 1247 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE- 1305
Query: 204 DKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYT 263
C +D++ ++DGP +S LI +VC +F SSSN +++ +D++ + RGF A Y
Sbjct: 1306 -GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 1364
Query: 264 SIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPT----CRPKLS-NVVEF 318
S + + ++T+L C + M+ +S+SYL++ + ++L + CRP+++ N+V F
Sbjct: 1365 S--SPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIF 1422
Query: 319 SVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI 378
++P +GCGT ++ ++ +I Y+N +T A+ + +I R+ L+I V C M N+ V+ +YI
Sbjct: 1423 TIPYSGCGTFKQADNDTIDYSNFLT--AAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYI 1480
Query: 379 TEDDVIQSQNAL-------GKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTS 431
D + + N + G ++ +++ + S+SF + PYYVDLNQ L+VQ + S
Sbjct: 1481 ANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHS 1540
Query: 432 DPNLVVFLDTCRASPTS-DFASPTYDLIKSGCSRDETCKVYPLFG-HYGRFQFNAFKFLR 489
D L +F+DTC ASP S DF S TYDLI+SGC RD+T Y RF+F AF FL
Sbjct: 1541 DAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLN 1600
Query: 490 SMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLK 541
SVYL+CK+++C + D SRC +GCV RSKRD+ SY+ K D ++GPI+L+
Sbjct: 1601 RFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQ 1652
Score = 97.4 bits (241), Expect = 3e-20
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 153 NCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFL 212
NCGG+L G+F+SP+YP +P A CVW I+V Y+I L F + LE C FD++
Sbjct: 1014 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1073
Query: 213 AIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE---- 268
I+DG +S L+G++C F SS N +T+ +D + GF A Y S ++
Sbjct: 1074 EIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1133
Query: 269 --NINTTSLTCS 278
N+N++ C+
Sbjct: 1134 LVNLNSSYGLCA 1145
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE N + +IF VQL+ G C + I+VFDG + PL+ +VC + F
Sbjct: 1283 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC--DGARGSFT 1338
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SSS+ ++ + ++D + I R F Y+ SP+
Sbjct: 1339 SSSNFMSIRFISDHS-ITRRGFRAEYYSSPS 1368
Score = 50.4 bits (119), Expect = 5e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE I + FS ++L+ +C + +++FDG+ ++ LLG++C ND +F
Sbjct: 1041 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC--NDTRQIFT 1098
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SS + +T +D + Q T F+ +Y P+
Sbjct: 1099 SSYNRMTIHFRSDIS-FQNTGFLAWYNSFPS 1128
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 296 bits (759), Expect = 3e-80
Identities = 160/412 (38%), Positives = 255/412 (61%), Gaps = 24/412 (5%)
Query: 148 NISIPN----CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEI 203
NI+ PN CGG+L G F+SP YP +P A CVW I+V+ +Y++ + F+++ LE
Sbjct: 1373 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE- 1431
Query: 204 DKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYT 263
C +D++ ++DGP +S LI +VC +F SSSN +++ +D++ + RGF A Y
Sbjct: 1432 -GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 1490
Query: 264 SIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPT----CRPKLS-NVVEF 318
S + + ++T+L C + M+ +S+SYL++ + ++L + CRP+++ N+V F
Sbjct: 1491 S--SPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIF 1548
Query: 319 SVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI 378
++P +GCGT ++ ++ +I Y+N +T A+ + +I R+ L+I V C M N+ V+ +YI
Sbjct: 1549 TIPYSGCGTFKQADNDTIDYSNFLT--AAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYI 1606
Query: 379 TEDDVIQSQNAL-------GKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTS 431
D + + N + G ++ +++ + S+SF + PYYVDLNQ L+VQ + S
Sbjct: 1607 ANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHS 1666
Query: 432 DPNLVVFLDTCRASPTS-DFASPTYDLIKSGCSRDETCKVYPLFG-HYGRFQFNAFKFLR 489
D L +F+DTC ASP S DF S TYDLI+SGC RD+T Y RF+F AF FL
Sbjct: 1667 DAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLN 1726
Query: 490 SMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLK 541
SVYL+CK+++C + D SRC +GCV RSKRD+ SY+ K D ++GPI+L+
Sbjct: 1727 RFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQ 1778
Score = 97.4 bits (241), Expect = 3e-20
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 153 NCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFL 212
NCGG+L G+F+SP+YP +P A CVW I+V Y+I L F + LE C FD++
Sbjct: 1140 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1199
Query: 213 AIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE---- 268
I+DG +S L+G++C F SS N +T+ +D + GF A Y S ++
Sbjct: 1200 EIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1259
Query: 269 --NINTTSLTCS 278
N+N++ C+
Sbjct: 1260 LVNLNSSYGLCA 1271
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE N + +IF VQL+ G C + I+VFDG + PL+ +VC + F
Sbjct: 1409 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC--DGARGSFT 1464
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SSS+ ++ + ++D + I R F Y+ SP+
Sbjct: 1465 SSSNFMSIRFISDHS-ITRRGFRAEYYSSPS 1494
Score = 50.4 bits (119), Expect = 5e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE I + FS ++L+ +C + +++FDG+ ++ LLG++C ND +F
Sbjct: 1167 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC--NDTRQIFT 1224
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SS + +T +D + Q T F+ +Y P+
Sbjct: 1225 SSYNRMTIHFRSDIS-FQNTGFLAWYNSFPS 1254
>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
[Homo sapiens]
Length = 2403
Score = 296 bits (759), Expect = 3e-80
Identities = 160/412 (38%), Positives = 255/412 (61%), Gaps = 24/412 (5%)
Query: 148 NISIPN----CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEI 203
NI+ PN CGG+L G F+SP YP +P A CVW I+V+ +Y++ + F+++ LE
Sbjct: 1988 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE- 2046
Query: 204 DKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYT 263
C +D++ ++DGP +S LI +VC +F SSSN +++ +D++ + RGF A Y
Sbjct: 2047 -GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 2105
Query: 264 SIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPT----CRPKLS-NVVEF 318
S + + ++T+L C + M+ +S+SYL++ + ++L + CRP+++ N+V F
Sbjct: 2106 S--SPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIF 2163
Query: 319 SVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI 378
++P +GCGT ++ ++ +I Y+N +T A+ + +I R+ L+I V C M N+ V+ +YI
Sbjct: 2164 TIPYSGCGTFKQADNDTIDYSNFLT--AAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYI 2221
Query: 379 TEDDVIQSQNAL-------GKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTS 431
D + + N + G ++ +++ + S+SF + PYYVDLNQ L+VQ + S
Sbjct: 2222 ANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHS 2281
Query: 432 DPNLVVFLDTCRASPTS-DFASPTYDLIKSGCSRDETCKVYPLFG-HYGRFQFNAFKFLR 489
D L +F+DTC ASP S DF S TYDLI+SGC RD+T Y RF+F AF FL
Sbjct: 2282 DAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLN 2341
Query: 490 SMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLK 541
SVYL+CK+++C + D SRC +GCV RSKRD+ SY+ K D ++GPI+L+
Sbjct: 2342 RFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQ 2393
Score = 97.4 bits (241), Expect = 3e-20
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 153 NCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFL 212
NCGG+L G+F+SP+YP +P A CVW I+V Y+I L F + LE C FD++
Sbjct: 1755 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1814
Query: 213 AIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE---- 268
I+DG +S L+G++C F SS N +T+ +D + GF A Y S ++
Sbjct: 1815 EIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1874
Query: 269 --NINTTSLTCS 278
N+N++ C+
Sbjct: 1875 LVNLNSSYGLCA 1886
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE N + +IF VQL+ G C + I+VFDG + PL+ +VC + F
Sbjct: 2024 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC--DGARGSFT 2079
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SSS+ ++ + ++D + I R F Y+ SP+
Sbjct: 2080 SSSNFMSIRFISDHS-ITRRGFRAEYYSSPS 2109
Score = 50.4 bits (119), Expect = 5e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE I + FS ++L+ +C + +++FDG+ ++ LLG++C ND +F
Sbjct: 1782 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC--NDTRQIFT 1839
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SS + +T +D + Q T F+ +Y P+
Sbjct: 1840 SSYNRMTIHFRSDIS-FQNTGFLAWYNSFPS 1869
>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
[Homo sapiens]
Length = 2413
Score = 296 bits (759), Expect = 3e-80
Identities = 160/412 (38%), Positives = 255/412 (61%), Gaps = 24/412 (5%)
Query: 148 NISIPN----CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEI 203
NI+ PN CGG+L G F+SP YP +P A CVW I+V+ +Y++ + F+++ LE
Sbjct: 1998 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE- 2056
Query: 204 DKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYT 263
C +D++ ++DGP +S LI +VC +F SSSN +++ +D++ + RGF A Y
Sbjct: 2057 -GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 2115
Query: 264 SIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPT----CRPKLS-NVVEF 318
S + + ++T+L C + M+ +S+SYL++ + ++L + CRP+++ N+V F
Sbjct: 2116 S--SPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIF 2173
Query: 319 SVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI 378
++P +GCGT ++ ++ +I Y+N +T A+ + +I R+ L+I V C M N+ V+ +YI
Sbjct: 2174 TIPYSGCGTFKQADNDTIDYSNFLT--AAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYI 2231
Query: 379 TEDDVIQSQNAL-------GKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTS 431
D + + N + G ++ +++ + S+SF + PYYVDLNQ L+VQ + S
Sbjct: 2232 ANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHS 2291
Query: 432 DPNLVVFLDTCRASPTS-DFASPTYDLIKSGCSRDETCKVYPLFG-HYGRFQFNAFKFLR 489
D L +F+DTC ASP S DF S TYDLI+SGC RD+T Y RF+F AF FL
Sbjct: 2292 DAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLN 2351
Query: 490 SMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLK 541
SVYL+CK+++C + D SRC +GCV RSKRD+ SY+ K D ++GPI+L+
Sbjct: 2352 RFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQ 2403
Score = 97.4 bits (241), Expect = 3e-20
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 153 NCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFL 212
NCGG+L G+F+SP+YP +P A CVW I+V Y+I L F + LE C FD++
Sbjct: 1765 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
Query: 213 AIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE---- 268
I+DG +S L+G++C F SS N +T+ +D + GF A Y S ++
Sbjct: 1825 EIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1884
Query: 269 --NINTTSLTCS 278
N+N++ C+
Sbjct: 1885 LVNLNSSYGLCA 1896
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE N + +IF VQL+ G C + I+VFDG + PL+ +VC + F
Sbjct: 2034 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC--DGARGSFT 2089
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SSS+ ++ + ++D + I R F Y+ SP+
Sbjct: 2090 SSSNFMSIRFISDHS-ITRRGFRAEYYSSPS 2119
Score = 50.4 bits (119), Expect = 5e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE I + FS ++L+ +C + +++FDG+ ++ LLG++C ND +F
Sbjct: 1792 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC--NDTRQIFT 1849
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SS + +T +D + Q T F+ +Y P+
Sbjct: 1850 SSYNRMTIHFRSDIS-FQNTGFLAWYNSFPS 1879
>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
[Homo sapiens]
Length = 1785
Score = 296 bits (759), Expect = 3e-80
Identities = 160/412 (38%), Positives = 255/412 (61%), Gaps = 24/412 (5%)
Query: 148 NISIPN----CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEI 203
NI+ PN CGG+L G F+SP YP +P A CVW I+V+ +Y++ + F+++ LE
Sbjct: 1370 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE- 1428
Query: 204 DKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYT 263
C +D++ ++DGP +S LI +VC +F SSSN +++ +D++ + RGF A Y
Sbjct: 1429 -GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 1487
Query: 264 SIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPT----CRPKLS-NVVEF 318
S + + ++T+L C + M+ +S+SYL++ + ++L + CRP+++ N+V F
Sbjct: 1488 S--SPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIF 1545
Query: 319 SVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI 378
++P +GCGT ++ ++ +I Y+N +T A+ + +I R+ L+I V C M N+ V+ +YI
Sbjct: 1546 TIPYSGCGTFKQADNDTIDYSNFLT--AAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYI 1603
Query: 379 TEDDVIQSQNAL-------GKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTS 431
D + + N + G ++ +++ + S+SF + PYYVDLNQ L+VQ + S
Sbjct: 1604 ANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHS 1663
Query: 432 DPNLVVFLDTCRASPTS-DFASPTYDLIKSGCSRDETCKVYPLFG-HYGRFQFNAFKFLR 489
D L +F+DTC ASP S DF S TYDLI+SGC RD+T Y RF+F AF FL
Sbjct: 1664 DAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLN 1723
Query: 490 SMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLK 541
SVYL+CK+++C + D SRC +GCV RSKRD+ SY+ K D ++GPI+L+
Sbjct: 1724 RFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQ 1775
Score = 97.4 bits (241), Expect = 3e-20
Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 153 NCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFL 212
NCGG+L G+F+SP+YP +P A CVW I+V Y+I L F + LE C FD++
Sbjct: 1137 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1196
Query: 213 AIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE---- 268
I+DG +S L+G++C F SS N +T+ +D + GF A Y S ++
Sbjct: 1197 EIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1256
Query: 269 --NINTTSLTCS 278
N+N++ C+
Sbjct: 1257 LVNLNSSYGLCA 1268
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE N + +IF VQL+ G C + I+VFDG + PL+ +VC + F
Sbjct: 1406 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC--DGARGSFT 1461
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SSS+ ++ + ++D + I R F Y+ SP+
Sbjct: 1462 SSSNFMSIRFISDHS-ITRRGFRAEYYSSPS 1491
Score = 50.4 bits (119), Expect = 5e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W IE I + FS ++L+ +C + +++FDG+ ++ LLG++C ND +F
Sbjct: 1164 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC--NDTRQIFT 1221
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148
SS + +T +D + Q T F+ +Y P+
Sbjct: 1222 SSYNRMTIHFRSDIS-FQNTGFLAWYNSFPS 1251
>gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]
Length = 449
Score = 108 bits (271), Expect = 1e-23
Identities = 64/216 (29%), Positives = 113/216 (52%), Gaps = 5/216 (2%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
P++ C WTI PE +++ + F L+ +C + ++VF G+ ++G LG+ C
Sbjct: 59 PNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPA 118
Query: 114 PVFESSSSTLTFQIVTDSARIQRTVFVFYY-FFSPNISIPNCGGYLDTLEGSFTSPNYPK 172
P+ + + +T ++ TD R ++Y + CGG L+ +G+ T+PN+P+
Sbjct: 119 PLV-APGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPE 177
Query: 173 -PHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGP-STNSGLIGQVCG 230
+P C WHI D I L F++ LE D C++D +++++G S +S +G+ CG
Sbjct: 178 SDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCG 237
Query: 231 RVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
P + S N L V +D + + GFSASY ++
Sbjct: 238 DAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTL 273
Score = 65.1 bits (157), Expect = 2e-10
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Query: 146 SPNISIPN--CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEI 203
+PN + P CGG + G S +P +P C+W I V + + L+F+ LE+
Sbjct: 27 TPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLEL 86
Query: 204 DKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPT-FESSSNSLTVVLSTDYANSYRGFSASY 262
C++D L ++ G T+ +G+ CG P + N +T+ ++TD RGF Y
Sbjct: 87 HPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY 146
Query: 263 T 263
+
Sbjct: 147 S 147
>gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]
Length = 415
Score = 108 bits (271), Expect = 1e-23
Identities = 65/214 (30%), Positives = 107/214 (50%), Gaps = 8/214 (3%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
P+ CTW I PE K + + F ++ L+ D C + + V++G +NG +G+ C +
Sbjct: 55 PNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNG-HANGQRIGRFCGT--FR 111
Query: 114 P-VFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPN-CGGYLDTLEGSFTSPNYP 171
P SS + + Q+++D+ + PN CGG LD GSF +PN+P
Sbjct: 112 PGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWP 171
Query: 172 -KPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSG-LIGQVC 229
+ +P CVWHI K+ I+L F++ +E D C++D++A+++G N IG+ C
Sbjct: 172 DRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYC 231
Query: 230 GRVTPT-FESSSNSLTVVLSTDYANSYRGFSASY 262
G P S N L + +D + + GF Y
Sbjct: 232 GDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 70.5 bits (171), Expect = 4e-12
Identities = 40/120 (33%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Query: 146 SPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDK 205
SP + CGG L G S +P +P + C W I V + + LNF+ I LE D
Sbjct: 25 SPERPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDN 84
Query: 206 QCKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTS 264
C++DF+ +Y+G N IG+ CG P SS N + V + +D + GF A +++
Sbjct: 85 LCRYDFVDVYNG-HANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSA 143
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 106 bits (265), Expect = 5e-23
Identities = 65/211 (30%), Positives = 104/211 (49%), Gaps = 8/211 (3%)
Query: 56 ENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPV 115
++CT T+ P+N +I + F + ++ C ++ ++V +G++SN PLLG+ C PV
Sbjct: 3419 KDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPV 3478
Query: 116 FESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHP 175
F S ++ L + +DS R + + S CGG L GSFTSP YP +P
Sbjct: 3479 F-SQNNELYLRFKSDSVTSDRGYEIIW-----TSSPSGCGGTLYGDRGSFTSPGYPGTYP 3532
Query: 176 ELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVT-- 233
YC W + + +NF I ++ C ++L +YDGP+ +S G CG T
Sbjct: 3533 NNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSI 3592
Query: 234 PTFESSSNSLTVVLSTDYANSYRGFSASYTS 264
F +SSN + + DYA F ++ S
Sbjct: 3593 APFVASSNQVFIKFHADYARRPSAFRLTWDS 3623
Score = 105 bits (262), Expect = 1e-22
Identities = 60/215 (27%), Positives = 103/215 (47%), Gaps = 15/215 (6%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
+++C WTI ++ F L+ +C ++ ++++DG G G D P
Sbjct: 1303 NQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQMGRYCGV-----DLPP 1357
Query: 115 VFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPH 174
++SS L ++TD + F +F + CGG L GSF+SP +P +
Sbjct: 1358 PGSTTSSKLQVLLLTDGVGRREKGFQMQWF------VYGCGGELSGATGSFSSPGFPNRY 1411
Query: 175 PELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP 234
P C+W+I+ + I+L + +E +C FD L IY GP +S I Q+C + +P
Sbjct: 1412 PPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSP 1471
Query: 235 ----TFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
S+ N L + TD + + RGF+AS+ ++
Sbjct: 1472 ENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 1506
Score = 105 bits (261), Expect = 2e-22
Identities = 69/207 (33%), Positives = 101/207 (48%), Gaps = 8/207 (3%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPD-GSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
C + I + I + F+ L+ G+ ++ +++ DG PLLG N P
Sbjct: 1074 CIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGSN-LPPTI 1132
Query: 117 ESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPE 176
S S+ L + +D R+ F Y+ + S CGG L T G+F SPNYP P+
Sbjct: 1133 ISHSNKLWLKFKSDQIDT-RSGFSAYW----DGSSTGCGGNLTTSSGTFISPNYPMPYYH 1187
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCG-RVTPT 235
+ C W ++ +L FK+ LE C D+LA+YDGPS+NS L+ Q+CG P
Sbjct: 1188 SSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPL 1247
Query: 236 FESSSNSLTVVLSTDYANSYRGFSASY 262
SS +S+ + L TD RGF A Y
Sbjct: 1248 IRSSGDSMFIKLRTDEGQQGRGFKAEY 1274
Score = 104 bits (260), Expect = 2e-22
Identities = 66/209 (31%), Positives = 103/209 (49%), Gaps = 9/209 (4%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W ++ + I F L CE + ++++D +S G +LG+ C N +
Sbjct: 2363 CEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTS-GNILGRYCG-NTIPDSID 2420
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPEL 177
+SS+T + VTD + T F F S+ CGG L G+FTSPNYP P+P
Sbjct: 2421 TSSNTAVVRFVTDGSV---TASGFRLRFES--SMEECGGDLQGSIGTFTSPNYPNPNPHG 2475
Query: 178 AYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFE 237
C W I + +I L F + L C + + +++G +NS + ++C V + E
Sbjct: 2476 RICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNE 2535
Query: 238 --SSSNSLTVVLSTDYANSYRGFSASYTS 264
SS N++ V+ TD + Y GF+ASYTS
Sbjct: 2536 IKSSGNTMKVIFFTDGSRPYGGFTASYTS 2564
Score = 104 bits (259), Expect = 3e-22
Identities = 65/218 (29%), Positives = 111/218 (50%), Gaps = 10/218 (4%)
Query: 55 SENCTWTIE-RPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
++NC+W I+ +P I + F++ +L+ +C + +++ DG + PL G+ C +
Sbjct: 1644 NQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPH 1703
Query: 114 PVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKP 173
P+ S SS LT + V+DS+ + + + S+ CGG EG F SP YP
Sbjct: 1704 PI-TSFSSALTLRFVSDSS-----ISAGGFHTTVTASVSACGGTFYMAEGIFNSPGYPDI 1757
Query: 174 HPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVT 233
+P CVW+I +++L+F LE + C DF+ I +G +T L+G+ CG
Sbjct: 1758 YPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREGNATGH-LVGRYCGNSF 1816
Query: 234 PTFESS--SNSLTVVLSTDYANSYRGFSASYTSIYAEN 269
P SS ++L V +D + S GF A++ I+ +
Sbjct: 1817 PLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFGND 1854
Score = 99.0 bits (245), Expect = 1e-20
Identities = 65/241 (26%), Positives = 115/241 (47%), Gaps = 12/241 (4%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C WTI +P+++ I + F+ ++ CE++ +++ + P + C + +P F
Sbjct: 842 CRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTD--IPSFI 899
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPEL 177
+S + S+ + F+ F + +++ CG L G+ SP +P +P
Sbjct: 900 TSVYNFLYVTFVKSSSTENHGFMAK-FSAEDLA---CGEILTESTGTIQSPGHPNVYPHG 955
Query: 178 AYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGR-VTPTF 236
C WHI V+ ++ I L F+ LE C D+L +YD S S +G+ CG+ + P+
Sbjct: 956 INCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS--LGRYCGKSIPPSL 1013
Query: 237 ESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSDRMRVIISKSYLEAFNS 296
SS NSL +V TD +Y GF +Y +I A T L +D + S ++ + +
Sbjct: 1014 TSSGNSLMLVFVTDSDLAYEGFLINYEAISAA---TACLQDYTDDLGTFTSPNFPNNYPN 1070
Query: 297 N 297
N
Sbjct: 1071 N 1071
Score = 99.0 bits (245), Expect = 1e-20
Identities = 67/214 (31%), Positives = 103/214 (48%), Gaps = 11/214 (5%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
+C +TI ++K I + FS + P SC + + ++DG +++ PLLG+ C P
Sbjct: 3063 HCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGANTSDPLLGKFCGSKR-PPNV 3121
Query: 117 ESSSSTLTFQIVTDSARIQRT-VFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKP-- 173
+SS++++ TDS + + F P CGGYL +F SP+
Sbjct: 3122 KSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQ---QGCGGYLTGSNNTFASPDSDSNGM 3178
Query: 174 HPELAYCVWHIQVEKDYKIKLNFKEIFLEID---KQCKFDFLAIYDGPSTNSGLIGQVCG 230
+ + CVW I + I L F LE ++C +D++ +YDG S N+ L G CG
Sbjct: 3179 YDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCG 3238
Query: 231 RVTPT-FESSSNSLTVVLSTDYANSYRGFSASYT 263
P F SS N LTV +D GF+A+YT
Sbjct: 3239 STVPAPFISSGNFLTVQFISDLTLEREGFNATYT 3272
Score = 98.2 bits (243), Expect = 2e-20
Identities = 66/232 (28%), Positives = 106/232 (45%), Gaps = 7/232 (3%)
Query: 32 CTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIK 91
C SL G N + ++++ + NC W I+ K +RI F++ +L+ +C E ++
Sbjct: 474 CGESLSGINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQ 533
Query: 92 VFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISI 151
V+DG SS+ LG+ C + + SS + L F + ++ R R V +
Sbjct: 534 VYDGDSSSAFQLGRFCGSSLPHELL-SSDNALYFHLYSEHLRNGRGFTVRW-----ETQQ 587
Query: 152 PNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDF 211
P CGG L GS SP YP +P CVW + D + F + LE C D+
Sbjct: 588 PECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDY 647
Query: 212 LAIYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTDYANSYRGFSASY 262
L I DGP L+G+ C + P +++ + +D S +GF +Y
Sbjct: 648 LEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 699
Score = 93.2 bits (230), Expect = 6e-19
Identities = 65/224 (29%), Positives = 104/224 (46%), Gaps = 19/224 (8%)
Query: 57 NCTWTIERPE--NKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
NC WT+ P N SI I F L+ C+ + ++ G ++GPL+ ++C +
Sbjct: 2598 NCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFRVG-DADGPLMWRLCGPSKPTL 2656
Query: 115 VFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPH 174
S + VT+ R++ F Y F+ +CGG G TSPNYP +
Sbjct: 2657 PLVIPYSQVWIHFVTNE-RVEHIGFHAKYSFT------DCGGIQIGDSGVITSPNYPNAY 2709
Query: 175 PELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP 234
L +C ++ + + I L F + +E C +D + + +G S S +IGQ CG P
Sbjct: 2710 DSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNP 2769
Query: 235 -TFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTC 277
T +S SN L V ++D++ GF A++ NT +L C
Sbjct: 2770 RTIQSGSNQLVVTFNSDHSLQGGGFYATW--------NTQTLGC 2805
Score = 89.7 bits (221), Expect = 7e-18
Identities = 70/250 (28%), Positives = 112/250 (44%), Gaps = 20/250 (8%)
Query: 24 AEAEGNASCTVSLGGANMAETHKAMILQLNPSE-----NCTWTIERPENKSIRIIFSYVQ 78
A A+G ++ VS G+N +I P + NCT+ IE + + F
Sbjct: 2907 APAQGFSASFVSRCGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFH 2966
Query: 79 LDP----DGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARI 134
L+ GSC ++ + + G S VC P+ + L F +
Sbjct: 2967 LEARSAVTGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVLLNFY-----SNE 3021
Query: 135 QRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYP-KPHPELAYCVWHIQVEKDYKIK 193
Q T F F + + I +CGG + G TSP Y +P +C++ I V D I+
Sbjct: 3022 QITDFGFKFSYR----IISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIE 3077
Query: 194 LNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYA 252
L F + + C D+LAIYDG +T+ L+G+ CG + P +SS+NS+ +V TD
Sbjct: 3078 LKFSDFDVVPSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSF 3137
Query: 253 NSYRGFSASY 262
+ +G+ S+
Sbjct: 3138 QTAKGWKMSF 3147
Score = 88.6 bits (218), Expect = 2e-17
Identities = 67/247 (27%), Positives = 116/247 (46%), Gaps = 19/247 (7%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
+C+ +E P+ +I + FS ++P +C +++ V +G S P++GQ C N
Sbjct: 2714 HCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCG-NSNPRTI 2772
Query: 117 ESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPE 176
+S S+ L +D + +Q F + + N CGG + G+ SP++P+ PE
Sbjct: 2773 QSGSNQLVVTFNSDHS-LQGGGF----YATWNTQTLGCGGIFHSDNGTIRSPHWPQNFPE 2827
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFL--EIDKQCKFDFLAIYDG-PSTNSGLIGQVCGRVT 233
+ C W K ++++F FL D QC+ F+ ++ G + L+ CG V
Sbjct: 2828 NSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVA 2887
Query: 234 P-TFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSDRMRVIISKSYLE 292
P + SN+ T V + A + +GFSAS+ S N S IIS +Y +
Sbjct: 2888 PGPVITPSNTFTAVFQSQEAPA-QGFSASFVSRCGSNFTGPS--------GYIISPNYPK 2938
Query: 293 AFNSNGN 299
+++N N
Sbjct: 2939 QYDNNMN 2945
Score = 88.2 bits (217), Expect = 2e-17
Identities = 65/255 (25%), Positives = 109/255 (42%), Gaps = 14/255 (5%)
Query: 32 CTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIK 91
C L GA + + + P++ C W I SI++ ++ C + ++
Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLE 1450
Query: 92 VFDGTSSNGPLLGQVCSKNDYVPVFESSSS--TLTFQIVTDSARIQRTVFVFYYFFSPNI 149
++ G + P + Q+C++ + SS+ L + TD + R + S
Sbjct: 1451 IYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRG-----FNASWQA 1505
Query: 150 SIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKF 209
CGG G SPNYP P+ C W I+V++++++ LNF + LE C
Sbjct: 1506 VTGGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC-- 1563
Query: 210 DFLAIYDGPSTNSGLIGQVCGR--VTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYA 267
+ YDG S+ + + CGR + SS NSL + + + RGF A +
Sbjct: 1564 --IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACG 1621
Query: 268 ENINTTSL-TCSSDR 281
+I T+S T SS R
Sbjct: 1622 GHILTSSFDTVSSPR 1636
Score = 84.3 bits (207), Expect = 3e-16
Identities = 68/263 (25%), Positives = 117/263 (44%), Gaps = 19/263 (7%)
Query: 13 LILSCLAELTMAEAEGNASCTVS---LGGANMAETHKAMILQLNPSEN------CTWTIE 63
L + +++LT+ NA+ T+ GG A I N S+ CTW I+
Sbjct: 3252 LTVQFISDLTLEREGFNATYTIMDMPCGGTYNATWTPQNISSPNSSDPDVPFSICTWVID 3311
Query: 64 RPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKN-DYVPVFESSSST 122
P ++ ++I +QL C +++ D +G Q C +N VPVF SS ST
Sbjct: 3312 SPPHQQVKITVWALQLTSQ-DCTQNYLQLQDSPQGHGNSRFQFCGRNASAVPVFYSSMST 3370
Query: 123 LTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVW 182
++ S + R + + + I +C G+ SP +P + C
Sbjct: 3371 A--MVIFKSGVVNRNSRMSFTY-----QIADCNRDYHKAFGNLRSPGWPDNYDNDKDCTV 3423
Query: 183 HIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPT-FESSSN 241
+ +++ I L F + +E +C+ DFL + +G ++NS L+G+ CG + P S +N
Sbjct: 3424 TLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNN 3483
Query: 242 SLTVVLSTDYANSYRGFSASYTS 264
L + +D S RG+ +TS
Sbjct: 3484 ELYLRFKSDSVTSDRGYEIIWTS 3506
Score = 84.0 bits (206), Expect = 4e-16
Identities = 60/213 (28%), Positives = 102/213 (47%), Gaps = 12/213 (5%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
C W I PE + I ++F+ ++L SC +E++ VF+G SN P L ++CS + +
Sbjct: 2478 CEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIK 2537
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYL-DTLEGSFTSPNYP--KPH 174
SS +T+ TD +R Y + CGG L +T EG+FTSP Y + +
Sbjct: 2538 SSGNTMKVIFFTDGSRPYGGFTASYTSSEDAV----CGGSLPNTPEGNFTSPGYDGVRNY 2593
Query: 175 PELAYCVWHIQ--VEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRV 232
C W + + + I ++F++ +LE + C+FD L G + L+ ++CG
Sbjct: 2594 SRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFRVG-DADGPLMWRLCGPS 2652
Query: 233 TPTFE--SSSNSLTVVLSTDYANSYRGFSASYT 263
PT + + + T+ + GF A Y+
Sbjct: 2653 KPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYS 2685
Score = 81.6 bits (200), Expect = 2e-15
Identities = 66/206 (32%), Positives = 94/206 (45%), Gaps = 8/206 (3%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
NCTW I N I ++F L+ +C ++ ++V+D S LG+ C K+ P
Sbjct: 957 NCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS--LGRYCGKS-IPPSL 1013
Query: 117 ESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPE 176
SS ++L VTDS + Y S + Y D L G+FTSPN+P +P
Sbjct: 1014 TSSGNSLMLVFVTDSDLAYEGFLINYEAISAATACLQ--DYTDDL-GTFTSPNFPNNYPN 1070
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFL-EIDKQCKFDFLAIYDGPSTNSGLIGQVCG-RVTP 234
C++ I V I ++F L E DFL I DG S L+G G + P
Sbjct: 1071 NWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGSNLPP 1130
Query: 235 TFESSSNSLTVVLSTDYANSYRGFSA 260
T S SN L + +D ++ GFSA
Sbjct: 1131 TIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/214 (24%), Positives = 96/214 (44%), Gaps = 8/214 (3%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
P+ C W I +++ F QL+ C + +++ +G ++ G L+G+ C + +
Sbjct: 1760 PNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREGNAT-GHLVGRYCGNSFPL 1818
Query: 114 PVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKP 173
TL + ++D + + N +I G SP +P+
Sbjct: 1819 NYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFGNDNIVGT-------HGKVASPFWPEN 1871
Query: 174 HPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVT 233
+P + W + V + + E+ +E + C +D L IYDGPS ++ LIG CG T
Sbjct: 1872 YPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHARLIGAYCGTQT 1931
Query: 234 PTFESSSNSLTVVLSTDYANSYRGFSASYTSIYA 267
+F S+ NSLT +D + S +GF + ++ A
Sbjct: 1932 ESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDA 1965
Score = 80.9 bits (198), Expect = 3e-15
Identities = 55/197 (27%), Positives = 87/197 (44%), Gaps = 12/197 (6%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
S C W ++ + + F L+ +C + + V+DG SSN LL Q+C ++ P
Sbjct: 1188 SSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCG-DEKPP 1246
Query: 115 VFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPH 174
+ SS ++ ++ TD + R Y N+ I N G S YP P+
Sbjct: 1247 LIRSSGDSMFIKLRTDEGQQGRGFKAEYRQTCENVVIVN------QTYGILESIGYPNPY 1300
Query: 175 PELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCG-RVT 233
E +C W I+ + F LE C D+L +YDGP +G+ CG +
Sbjct: 1301 SENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQ----MGRYCGVDLP 1356
Query: 234 PTFESSSNSLTVVLSTD 250
P ++S+ L V+L TD
Sbjct: 1357 PPGSTTSSKLQVLLLTD 1373
Score = 80.9 bits (198), Expect = 3e-15
Identities = 54/218 (24%), Positives = 101/218 (46%), Gaps = 12/218 (5%)
Query: 54 PSENCTWTIERPENKSIRIIFS-YVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDY 112
P +C W + P I++ F ++ +C S +++ DG S+ P+L + C +
Sbjct: 2243 PHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGTS-- 2300
Query: 113 VPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPK 172
+P + SS + + R + + F SI CGG + G S +P
Sbjct: 2301 LPSSQWSSGEVMY------LRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPT 2354
Query: 173 -PHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGR 231
P+ + +C WH+Q + + ++F++ L+ C+ DF+ I+D T+ ++G+ CG
Sbjct: 2355 LPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDN-HTSGNILGRYCGN 2413
Query: 232 VTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
P + ++SSN+ V TD + + GF + S E
Sbjct: 2414 TIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEE 2451
Score = 79.7 bits (195), Expect = 7e-15
Identities = 56/216 (25%), Positives = 99/216 (45%), Gaps = 20/216 (9%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
+CTW I+ P++ ++ + + ++ +C +++ + DG ++ L +C + P+
Sbjct: 2005 DCTWLIQAPDS-TVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGPI- 2062
Query: 117 ESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPE 176
S+ F T + + R F + S CGGYL G TSP YP+ +P
Sbjct: 2063 -RSTGEYMFIRFTSDSSVTRAGFNASFHKS-------CGGYLHADRGIITSPKYPETYPS 2114
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFL--EIDKQC-KFDFLAIYDGPSTNS------GLIGQ 227
C WH+ V+ I ++F++ F D C + D+L + +GP S G G
Sbjct: 2115 NLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGH 2174
Query: 228 VCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASY 262
CG + T +S N + V +D++N +GF Y
Sbjct: 2175 FCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Score = 75.5 bits (184), Expect = 1e-13
Identities = 58/211 (27%), Positives = 92/211 (43%), Gaps = 15/211 (7%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
+C+W I N + + F+ L+P SC I +DG SS L + C +
Sbjct: 1535 DCSWVIRVDRNHRVLLNFTDFDLEPQDSC----IMAYDGLSSTMSRLARTCGREQLANPI 1590
Query: 117 ESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLE-GSFTSPNYPKPHP 175
SS ++L + + +R R + CGG++ T + +SP +P +P
Sbjct: 1591 VSSGNSLFLRFQSGPSRQNRGFRAQFR--------QACGGHILTSSFDTVSSPRFPANYP 1642
Query: 176 ELAYCVWHIQVEKDYK-IKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP 234
C W IQ + I L+F LE C DF+ I DG ++ L G+ CG P
Sbjct: 1643 NNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMP 1702
Query: 235 -TFESSSNSLTVVLSTDYANSYRGFSASYTS 264
S S++LT+ +D + S GF + T+
Sbjct: 1703 HPITSFSSALTLRFVSDSSISAGGFHTTVTA 1733
Score = 70.5 bits (171), Expect = 4e-12
Identities = 51/210 (24%), Positives = 90/210 (42%), Gaps = 9/210 (4%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
P +C W + + + F + L+ C + +++ DG PLLG+ C+ V
Sbjct: 612 PGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFS-V 670
Query: 114 PVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKP 173
P +++ +DS +I F Y SP S CGG EG P P
Sbjct: 671 PPLQTTGPFARIHFHSDS-QISDQGFHITYLTSP--SDLRCGGNYTDPEGELFLPELSGP 727
Query: 174 HPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVT 233
CV+ ++ + +I++NF + L+ +++ + DG + L+G+VCG T
Sbjct: 728 FTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDGET----LLGKVCGNGT 783
Query: 234 PT-FESSSNSLTVVLSTDYANSYRGFSASY 262
+ +S +NS+ + D + F A Y
Sbjct: 784 ISHIKSITNSVWIRFKIDASVEKASFRAVY 813
Score = 63.5 bits (153), Expect = 5e-10
Identities = 64/264 (24%), Positives = 118/264 (44%), Gaps = 25/264 (9%)
Query: 19 AELTMAEAEGNASCTVSLGG---ANMAETHKAMILQLNPSE-NCTWTIERPENKSIRIIF 74
++ ++ A NAS S GG A+ + PS NC+W + +I + F
Sbjct: 2075 SDSSVTRAGFNASFHKSCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHF 2134
Query: 75 SYVQLDPDG--SCESENIKVF-DGTSSNGPLLG------QVCSKNDYVPVFESSSSTLTF 125
P+G SC + V +G P LG C + +F +S + +
Sbjct: 2135 EQPFQIPNGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLF-TSDNQMFV 2193
Query: 126 QIVTDSARIQRTVFVFYYFFSPNISIPNCGG--YLDTLE--GSFTSPNYPKPHPELAYCV 181
Q ++D + + + Y S CGG Y+ + G TSPN+P +P A C+
Sbjct: 2194 QFISDHSNEGQGFKIKYEAKSLA-----CGGNVYIHDADSAGYVTSPNHPHNYPPHADCI 2248
Query: 182 WHIQVEKDYKIKLNFKEIF-LEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSS 240
W + + +I+L F++ F +E+ C ++L + DG +++ ++ + CG P+ + SS
Sbjct: 2249 WILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSS 2308
Query: 241 NSLTVV-LSTDYANSYRGFSASYT 263
+ + +D + ++ GF A Y+
Sbjct: 2309 GEVMYLRFRSDNSPTHVGFKAKYS 2332
Score = 63.2 bits (152), Expect = 7e-10
Identities = 54/211 (25%), Positives = 93/211 (44%), Gaps = 15/211 (7%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
+ C + +++P+ + I+I F++V+L I+V DG + LLG+VC N +
Sbjct: 731 TRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDGET----LLGKVCG-NGTIS 785
Query: 115 VFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPH 174
+S ++++ + D A +++ F Y + CG L T EG SP +P +
Sbjct: 786 HIKSITNSVWIRFKID-ASVEKASFRAVYQVA-------CGDEL-TGEGVIRSPFFPNVY 836
Query: 175 PELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP 234
P C W I + I LNF + C+ D++ I S + CG P
Sbjct: 837 PGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTDIP 896
Query: 235 TFESS-SNSLTVVLSTDYANSYRGFSASYTS 264
+F +S N L V + GF A +++
Sbjct: 897 SFITSVYNFLYVTFVKSSSTENHGFMAKFSA 927
Score = 53.5 bits (127), Expect = 5e-07
Identities = 56/218 (25%), Positives = 82/218 (37%), Gaps = 17/218 (7%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDP--DGSCESENIKVFDGTSS-NGPLLGQVCSKND 111
+ C+WT ++K + I F L P DG C++ +KV+ GT + LL C
Sbjct: 2828 NSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVA 2887
Query: 112 YVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYP 171
PV S+ TF V S F + + CG G SPNYP
Sbjct: 2888 PGPVITPSN---TFTAVFQSQEAPAQGFSASF-------VSRCGSNFTGPSGYIISPNYP 2937
Query: 172 KPHPELAYCVWHIQVEKDYKIKLNFKEIFLE----IDKQCKFDFLAIYDGPSTNSGLIGQ 227
K + C + I+ + L F LE + C D + I G S S
Sbjct: 2938 KQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFAT 2997
Query: 228 VCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
VCG P + + + + ++ + GF SY I
Sbjct: 2998 VCGDEMPAPLTIAGPVLLNFYSNEQITDFGFKFSYRII 3035
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 103 bits (257), Expect = 5e-22
Identities = 66/247 (26%), Positives = 108/247 (43%), Gaps = 37/247 (14%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
P + C W I E+ + + F +++ +C + ++V DGTS N PL+G+ C D
Sbjct: 484 PMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRDGTSENSPLIGRFCGY-DKP 542
Query: 114 PVFESSSSTLTFQIVTDSA---------------------------RIQRTVFVFYYFFS 146
S+S+TL + V+D R T+ +
Sbjct: 543 EDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPDRGGCEQRCLNTLGSYQCACE 602
Query: 147 PNISI--------PNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKE 198
P + CGG L L G+ T+P +PK +P CVW + Y+I + F+
Sbjct: 603 PGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEF 662
Query: 199 IFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRG 257
LE ++ CK+D++ I+ G S+ S L G+ CG P S N++ + +D S +G
Sbjct: 663 FELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKG 722
Query: 258 FSASYTS 264
F A + S
Sbjct: 723 FKAHFFS 729
Score = 98.6 bits (244), Expect = 1e-20
Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 12/208 (5%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP-V 115
+C W + + I + F+ + L C + I+V DG PLLG+ C D +P V
Sbjct: 374 HCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCG--DKLPEV 431
Query: 116 FESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHP 175
S+ S + + + S + + Y CGG + EG SPNYP +
Sbjct: 432 LTSTDSRMWIEFRSSSNWVGKGFAAVYEAI--------CGGEIRKNEGQIQSPNYPDDYR 483
Query: 176 ELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP- 234
+ CVW I V + Y + L F+ +E C +D+L + DG S NS LIG+ CG P
Sbjct: 484 PMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRDGTSENSPLIGRFCGYDKPE 543
Query: 235 TFESSSNSLTVVLSTDYANSYRGFSASY 262
S+SN+L + +D + GF+A++
Sbjct: 544 DIRSTSNTLWMKFVSDGTVNKAGFAANF 571
Score = 91.3 bits (225), Expect = 2e-18
Identities = 66/296 (22%), Positives = 121/296 (40%), Gaps = 45/296 (15%)
Query: 11 TLLILSCLAELTMAEAEGNASCTVSLGGA----NMAETHKAMILQLNPSENCTWTIERPE 66
TL C E SC + GG N T + P++NC W + P
Sbjct: 593 TLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPT 652
Query: 67 NKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP-VFESSSSTLTF 125
I + F + +L+ + C+ + ++++ G SS L G+ C VP V S + +
Sbjct: 653 QYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAE--VPEVITSQFNNMRI 710
Query: 126 QIVTDSARIQRTVFVFYYFFSPNISIPNCGGY---------------------------- 157
+ +D+ + + F ++F + + GG
Sbjct: 711 EFKSDNT-VSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDC 769
Query: 158 --------LDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKF 209
+ + G TSPN+P +P C W I ++IKL F E +E ++C +
Sbjct: 770 KEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAY 829
Query: 210 DFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTS 264
D L ++DG + S ++G++CG P ++ N + V +D + +GF A++++
Sbjct: 830 DHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHST 885
Score = 79.3 bits (194), Expect = 9e-15
Identities = 56/227 (24%), Positives = 104/227 (45%), Gaps = 23/227 (10%)
Query: 56 ENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPV 115
+ CTW I I++ FS +++ C ++++VFDG + P+LG++C P+
Sbjct: 798 KECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPL 857
Query: 116 FESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDT--------LEGSFTS 167
++ + + + V+D A +QR F + CGG L F
Sbjct: 858 V-ATGNKMFVRFVSD-ASVQRKGFQATH-------STECGGRLKAESKPRDLYSHAQFGD 908
Query: 168 PNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQ 227
NYP C W + E+ +++L+F+ +E + C +D++ ++DG + + +G+
Sbjct: 909 NNYPGQ----VDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGR 964
Query: 228 VCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSI-YAENINT 272
CG P S +S+ + TD + +GF Y SI Y + +T
Sbjct: 965 FCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIRYPDTTHT 1011
Score = 68.2 bits (165), Expect = 2e-11
Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
Query: 152 PNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDF 211
P CG L G+ +SP +P +P +C+W + V KI LNF + L C +D+
Sbjct: 347 PACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDY 406
Query: 212 LAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSY-RGFSASYTSI 265
+ + DG S L+G+ CG P +S++S + +N +GF+A Y +I
Sbjct: 407 IEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI 461
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 102 bits (253), Expect = 1e-21
Identities = 70/248 (28%), Positives = 109/248 (43%), Gaps = 39/248 (15%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
PS+ C W I E + + F +++ SC + ++V DG + L+G C
Sbjct: 486 PSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPE 545
Query: 114 PVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPN-ISIPN------------------- 153
V +SSS+ L + V+D + I + F +F + S P+
Sbjct: 546 DV-KSSSNRLWMKFVSDGS-INKAGFAANFFKEVDECSWPDHGGCEHRCVNTLGSYKCAC 603
Query: 154 ----------------CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFK 197
CGG++ L G+ TSP +PK +P CVW + Y+I L F+
Sbjct: 604 DPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFE 663
Query: 198 EIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYR 256
LE + CK+DF+ + G S ++ L G+ CG TP S SN++ V +D S R
Sbjct: 664 VFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKR 723
Query: 257 GFSASYTS 264
GF A + S
Sbjct: 724 GFRAHFFS 731
Score = 95.5 bits (236), Expect = 1e-19
Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 10/207 (4%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
+C W I + I + F+ + L C + ++V DG PLLG+ C P+
Sbjct: 376 HCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLV 435
Query: 117 ESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPE 176
S+ S L + + S + + F Y CGG ++ G SPNYP +
Sbjct: 436 -STDSRLWVEFRSSSNILGKGFFAAYE--------ATCGGDMNKDAGQIQSPNYPDDYRP 486
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-T 235
CVW I V + + + L F+ +E C +D+L + DGP+ S LIG CG P
Sbjct: 487 SKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIGHFCGYEKPED 546
Query: 236 FESSSNSLTVVLSTDYANSYRGFSASY 262
+SSSN L + +D + + GF+A++
Sbjct: 547 VKSSSNRLWMKFVSDGSINKAGFAANF 573
Score = 88.2 bits (217), Expect = 2e-17
Identities = 65/294 (22%), Positives = 122/294 (41%), Gaps = 41/294 (13%)
Query: 11 TLLILSCLAELTMAEAEGNASCTVSLGG----ANMAETHKAMILQLNPSENCTWTIERPE 66
TL C + A C V+ GG N T + ++NC W + P
Sbjct: 595 TLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPA 654
Query: 67 NKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQ 126
I + F +L+ + C+ + ++V G S + L G+ C ++ V S S+ + +
Sbjct: 655 QYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCG-SETPEVITSQSNNMRVE 713
Query: 127 IVTDSARIQRTVFVFYYFFSPNISIPNCG------------------GY----------- 157
+D+ +R ++ + N G GY
Sbjct: 714 FKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKE 773
Query: 158 ------LDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDF 211
+ ++EG+ SPN+P +P C W+I +++KL F E +E ++C +D
Sbjct: 774 AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833
Query: 212 LAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTS 264
L +YDGP + + ++G+ CG P +S +S+ + +D + +GF A +++
Sbjct: 834 LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887
Score = 87.8 bits (216), Expect = 3e-17
Identities = 58/216 (26%), Positives = 93/216 (43%), Gaps = 22/216 (10%)
Query: 58 CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117
CTW I +++ F+ +++ C ++++++DG S P+LG+ C P
Sbjct: 802 CTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVA 861
Query: 118 SSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDT--------LEGSFTSPN 169
S SS F A +QR F + CGG L F N
Sbjct: 862 SGSSM--FLRFYSDASVQRKGF-------QAVHSTECGGRLKAEVQTKELYSHAQFGDNN 912
Query: 170 YPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVC 229
YP A C W I E Y ++L F+ +E + C +D++ YDG +++ +G+ C
Sbjct: 913 YPSE----ARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFC 968
Query: 230 GR-VTPTFESSSNSLTVVLSTDYANSYRGFSASYTS 264
G S+ +SL + TD + +GF A YTS
Sbjct: 969 GSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTS 1004
Score = 68.2 bits (165), Expect = 2e-11
Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Query: 152 PNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDF 211
P CG L G+F++P +P +P ++CVW I V KI LNF + L + C +D+
Sbjct: 349 PACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDY 408
Query: 212 LAIYDGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENI 270
+ + DG + L+G+ CG ++ S+ + L V + +GF A+Y + ++
Sbjct: 409 VEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDM 468
Query: 271 N 271
N
Sbjct: 469 N 469
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 99.4 bits (246), Expect = 9e-21
Identities = 68/250 (27%), Positives = 109/250 (43%), Gaps = 41/250 (16%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCS--KND 111
PS+ C W I+ E + + F +++ SC + ++V DG S + L+G+ C K D
Sbjct: 457 PSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPD 516
Query: 112 YVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPN------------------ 153
+ +S+SS L + V+D + + V ++ S PN
Sbjct: 517 DI---KSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCS 573
Query: 154 -----------------CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNF 196
CGG+L L GS TSP +PK +P C+W + Y+I L F
Sbjct: 574 CDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQF 633
Query: 197 KEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSY 255
E + CK+DF+ + G + +S L G+ CG P S N++ V +D S
Sbjct: 634 DFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSK 693
Query: 256 RGFSASYTSI 265
+GF A + S+
Sbjct: 694 KGFKAHFFSV 703
Score = 88.2 bits (217), Expect = 2e-17
Identities = 57/207 (27%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
+C W I + I + F+ + L C + ++V DG PL G+ C P+
Sbjct: 347 HCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIV 406
Query: 117 ESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPE 176
S+ S L + + S + + F Y CGG + G SPNYP +
Sbjct: 407 -STDSRLWVEFRSSSNWVGKGFFAVYEAI--------CGGDVKKDYGHIQSPNYPDDYRP 457
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-T 235
C+W IQV + + + L F+ +E C +D+L + DG S +S LIG+ CG P
Sbjct: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
Query: 236 FESSSNSLTVVLSTDYANSYRGFSASY 262
+S+S+ L + +D + + GF+ ++
Sbjct: 518 IKSTSSRLWLKFVSDGSINKAGFAVNF 544
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Query: 152 PNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDF 211
P CG L G+F+SP YP + +CVW I V KI LNF + L + C +D+
Sbjct: 320 PACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDY 379
Query: 212 LAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
+ + DG + L G+ CG P S+ + L V + +GF A Y +I
Sbjct: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 37.7 bits (86), Expect = 0.031
Identities = 25/125 (20%), Positives = 56/125 (44%), Gaps = 2/125 (1%)
Query: 20 ELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQL 79
EL + A+C L N + T + P++NC W + P I + F + +
Sbjct: 579 ELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFET 638
Query: 80 DPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVF 139
+ + C+ + ++V G +++ L G+ C ++ V S + + + +D+ + + F
Sbjct: 639 EGNDVCKYDFVEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNT-VSKKGF 696
Query: 140 VFYYF 144
++F
Sbjct: 697 KAHFF 701
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 98.2 bits (243), Expect = 2e-20
Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 41/249 (16%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCS--KND 111
PS+ C W I+ E + + F +++ SC + ++V DG S + L+G+ C K D
Sbjct: 457 PSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPD 516
Query: 112 YVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPN------------------ 153
+ +S+SS L + V+D + + V ++ S PN
Sbjct: 517 DI---KSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCS 573
Query: 154 -----------------CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNF 196
CGG+L L GS TSP +PK +P C+W + Y+I L F
Sbjct: 574 CDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQF 633
Query: 197 KEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSY 255
E + CK+DF+ + G + +S L G+ CG P S N++ V +D S
Sbjct: 634 DFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSK 693
Query: 256 RGFSASYTS 264
+GF A + S
Sbjct: 694 KGFKAHFFS 702
Score = 88.2 bits (217), Expect = 2e-17
Identities = 57/207 (27%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
+C W I + I + F+ + L C + ++V DG PL G+ C P+
Sbjct: 347 HCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIV 406
Query: 117 ESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPE 176
S+ S L + + S + + F Y CGG + G SPNYP +
Sbjct: 407 -STDSRLWVEFRSSSNWVGKGFFAVYEAI--------CGGDVKKDYGHIQSPNYPDDYRP 457
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-T 235
C+W IQV + + + L F+ +E C +D+L + DG S +S LIG+ CG P
Sbjct: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
Query: 236 FESSSNSLTVVLSTDYANSYRGFSASY 262
+S+S+ L + +D + + GF+ ++
Sbjct: 518 IKSTSSRLWLKFVSDGSINKAGFAVNF 544
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Query: 152 PNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDF 211
P CG L G+F+SP YP + +CVW I V KI LNF + L + C +D+
Sbjct: 320 PACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDY 379
Query: 212 LAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
+ + DG + L G+ CG P S+ + L V + +GF A Y +I
Sbjct: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 37.7 bits (86), Expect = 0.031
Identities = 25/125 (20%), Positives = 56/125 (44%), Gaps = 2/125 (1%)
Query: 20 ELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQL 79
EL + A+C L N + T + P++NC W + P I + F + +
Sbjct: 579 ELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFET 638
Query: 80 DPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVF 139
+ + C+ + ++V G +++ L G+ C ++ V S + + + +D+ + + F
Sbjct: 639 EGNDVCKYDFVEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNT-VSKKGF 696
Query: 140 VFYYF 144
++F
Sbjct: 697 KAHFF 701
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 98.2 bits (243), Expect = 2e-20
Identities = 68/249 (27%), Positives = 108/249 (43%), Gaps = 41/249 (16%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCS--KND 111
PS+ C W I+ E + + F +++ SC + ++V DG S + L+G+ C K D
Sbjct: 457 PSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPD 516
Query: 112 YVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPN------------------ 153
+ +S+SS L + V+D + + V ++ S PN
Sbjct: 517 DI---KSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCS 573
Query: 154 -----------------CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNF 196
CGG+L L GS TSP +PK +P C+W + Y+I L F
Sbjct: 574 CDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQF 633
Query: 197 KEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSY 255
E + CK+DF+ + G + +S L G+ CG P S N++ V +D S
Sbjct: 634 DFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSK 693
Query: 256 RGFSASYTS 264
+GF A + S
Sbjct: 694 KGFKAHFFS 702
Score = 88.2 bits (217), Expect = 2e-17
Identities = 57/207 (27%), Positives = 95/207 (45%), Gaps = 10/207 (4%)
Query: 57 NCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVF 116
+C W I + I + F+ + L C + ++V DG PL G+ C P+
Sbjct: 347 HCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIV 406
Query: 117 ESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPE 176
S+ S L + + S + + F Y CGG + G SPNYP +
Sbjct: 407 -STDSRLWVEFRSSSNWVGKGFFAVYEAI--------CGGDVKKDYGHIQSPNYPDDYRP 457
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-T 235
C+W IQV + + + L F+ +E C +D+L + DG S +S LIG+ CG P
Sbjct: 458 SKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDD 517
Query: 236 FESSSNSLTVVLSTDYANSYRGFSASY 262
+S+S+ L + +D + + GF+ ++
Sbjct: 518 IKSTSSRLWLKFVSDGSINKAGFAVNF 544
Score = 81.3 bits (199), Expect = 2e-15
Identities = 53/218 (24%), Positives = 98/218 (44%), Gaps = 22/218 (10%)
Query: 56 ENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPV 115
+ CTW I +++ F + ++ C ++++VFDG + P+LG+ C PV
Sbjct: 771 KECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPV 830
Query: 116 FESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDT--------LEGSFTS 167
++ S + + +D++ +QR F + CGG + F
Sbjct: 831 L-ATGSRMFLRFYSDNS-VQRKGFQASH-------ATECGGQVRADVKTKDLYSHAQFGD 881
Query: 168 PNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQ 227
NYP C W I E+ Y ++L F+ +E + C +D++ ++DG + + +G+
Sbjct: 882 NNYPGG----VDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGR 937
Query: 228 VCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTS 264
CG P S+ +S+ V +D + +GF YTS
Sbjct: 938 YCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS 975
Score = 79.0 bits (193), Expect = 1e-14
Identities = 55/281 (19%), Positives = 114/281 (40%), Gaps = 37/281 (13%)
Query: 20 ELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQL 79
EL + A+C L N + T + P++NC W + P I + F + +
Sbjct: 579 ELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFET 638
Query: 80 DPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVF 139
+ + C+ + ++V G +++ L G+ C ++ V S + + + +D+ ++
Sbjct: 639 EGNDVCKYDFVEVRSGLTADSKLHGKFCG-SEKPEVITSQYNNMRVEFKSDNTVSKKGFK 697
Query: 140 VFYYFFSPNISIPN-----------------------------------CGGYLDTLEGS 164
++ S N C + + G+
Sbjct: 698 AHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGT 757
Query: 165 FTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGL 224
TSPN+P +P C W I +++KL F E+ +E +C +D L ++DG + +
Sbjct: 758 ITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPV 817
Query: 225 IGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTS 264
+G+ CG P ++ + + + +D + +GF AS+ +
Sbjct: 818 LGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHAT 858
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Query: 152 PNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDF 211
P CG L G+F+SP YP + +CVW I V KI LNF + L + C +D+
Sbjct: 320 PACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDY 379
Query: 212 LAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
+ + DG + L G+ CG P S+ + L V + +GF A Y +I
Sbjct: 380 VEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
Length = 609
Score = 95.9 bits (237), Expect = 1e-19
Identities = 72/220 (32%), Positives = 105/220 (47%), Gaps = 14/220 (6%)
Query: 53 NPSENCTWTIERPEN-KSIRIIFS-YVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKN 110
+PSE C W I+ P+ + I I F+ + L+ D C+ + ++VFDG + NG G+ C K
Sbjct: 49 HPSEKCEWLIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKI 107
Query: 111 DYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNY 170
PV SS L + V+D + Y F P C T G SP +
Sbjct: 108 APPPVV-SSGPFLFIKFVSDYETHGAGFSIRYEIFKRG---PECSQNYTTPSGVIKSPGF 163
Query: 171 PKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQ------CKFDFLAIYDGPSTNSGL 224
P+ +P C + + K +I L F+ LE D C++D L I+DG
Sbjct: 164 PEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPH 223
Query: 225 IGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYT 263
IG+ CG+ TP SSS L++V TD A + GFSA+Y+
Sbjct: 224 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/156 (29%), Positives = 70/156 (44%), Gaps = 8/156 (5%)
Query: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDY-KIKLNFKEIFLEIDKQCKFDFLAIYDGPSTN 221
G TSP YP + C W IQ Y +I +NF F D+ CK+D++ ++DG + N
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENEN 96
Query: 222 SGLIGQVCGRVT-PTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSD 280
G+ CG++ P SS L + +DY GFS Y + + T S
Sbjct: 97 GHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSG 156
Query: 281 RMRVIISKSYLEAFNSNGNNLQLKDPTCRPKLSNVV 316
VI S + E + N+L+ PK+S ++
Sbjct: 157 ---VIKSPGFPEKY---PNSLECTYIVFAPKMSEII 186
>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
Length = 644
Score = 95.9 bits (237), Expect = 1e-19
Identities = 72/220 (32%), Positives = 105/220 (47%), Gaps = 14/220 (6%)
Query: 53 NPSENCTWTIERPEN-KSIRIIFS-YVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKN 110
+PSE C W I+ P+ + I I F+ + L+ D C+ + ++VFDG + NG G+ C K
Sbjct: 49 HPSEKCEWLIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKI 107
Query: 111 DYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNY 170
PV SS L + V+D + Y F P C T G SP +
Sbjct: 108 APPPVV-SSGPFLFIKFVSDYETHGAGFSIRYEIFKRG---PECSQNYTTPSGVIKSPGF 163
Query: 171 PKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQ------CKFDFLAIYDGPSTNSGL 224
P+ +P C + + K +I L F+ LE D C++D L I+DG
Sbjct: 164 PEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPH 223
Query: 225 IGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYT 263
IG+ CG+ TP SSS L++V TD A + GFSA+Y+
Sbjct: 224 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/156 (29%), Positives = 70/156 (44%), Gaps = 8/156 (5%)
Query: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDY-KIKLNFKEIFLEIDKQCKFDFLAIYDGPSTN 221
G TSP YP + C W IQ Y +I +NF F D+ CK+D++ ++DG + N
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENEN 96
Query: 222 SGLIGQVCGRVT-PTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSD 280
G+ CG++ P SS L + +DY GFS Y + + T S
Sbjct: 97 GHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSG 156
Query: 281 RMRVIISKSYLEAFNSNGNNLQLKDPTCRPKLSNVV 316
VI S + E + N+L+ PK+S ++
Sbjct: 157 ---VIKSPGFPEKY---PNSLECTYIVFAPKMSEII 186
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 95.9 bits (237), Expect = 1e-19
Identities = 72/220 (32%), Positives = 105/220 (47%), Gaps = 14/220 (6%)
Query: 53 NPSENCTWTIERPEN-KSIRIIFS-YVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKN 110
+PSE C W I+ P+ + I I F+ + L+ D C+ + ++VFDG + NG G+ C K
Sbjct: 49 HPSEKCEWLIQAPDPYQRIMINFNPHFDLE-DRDCKYDYVEVFDGENENGHFRGKFCGKI 107
Query: 111 DYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNY 170
PV SS L + V+D + Y F P C T G SP +
Sbjct: 108 APPPVV-SSGPFLFIKFVSDYETHGAGFSIRYEIFKRG---PECSQNYTTPSGVIKSPGF 163
Query: 171 PKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQ------CKFDFLAIYDGPSTNSGL 224
P+ +P C + + K +I L F+ LE D C++D L I+DG
Sbjct: 164 PEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPH 223
Query: 225 IGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYT 263
IG+ CG+ TP SSS L++V TD A + GFSA+Y+
Sbjct: 224 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/156 (29%), Positives = 70/156 (44%), Gaps = 8/156 (5%)
Query: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDY-KIKLNFKEIFLEIDKQCKFDFLAIYDGPSTN 221
G TSP YP + C W IQ Y +I +NF F D+ CK+D++ ++DG + N
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENEN 96
Query: 222 SGLIGQVCGRVT-PTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSSD 280
G+ CG++ P SS L + +DY GFS Y + + T S
Sbjct: 97 GHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSG 156
Query: 281 RMRVIISKSYLEAFNSNGNNLQLKDPTCRPKLSNVV 316
VI S + E + N+L+ PK+S ++
Sbjct: 157 ---VIKSPGFPEKY---PNSLECTYIVFAPKMSEII 186
>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
Length = 449
Score = 95.9 bits (237), Expect = 1e-19
Identities = 73/257 (28%), Positives = 113/257 (43%), Gaps = 16/257 (6%)
Query: 12 LLILSCLAELTMAEAEGNASC--TVSLGGANMAETHKAMILQLNPSENCTWTIERPENKS 69
LL ++ L A+A C +S N + + + N C+W I E S
Sbjct: 10 LLAVALLGPGLQAQAMEGVKCGGVLSAPSGNFSSPNFPRLYPYNTE--CSWLIVVAEGSS 67
Query: 70 IRIIFSYVQLDPDGSCESENIKVFDGTSSN-GPLLGQVCSKNDYVPVFESSSSTLTFQIV 128
+ + F L+ +C + +++++G S + G LLG+ C K VP +SS ++
Sbjct: 68 VLLTFHAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGK---VPPPPFTSSWHVMSVI 124
Query: 129 TDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEK 188
S + V + FS CGG L L G TSP YP +P C W I+
Sbjct: 125 FHSDK-----HVASHGFSAGYQKDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAG 179
Query: 189 DYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRV-TPTFESSSNSLTVVL 247
+KL F + +E +++C +D++A+ GP G CG PT S + L VV
Sbjct: 180 PAHVKLVFVDFQVEGNEECTYDYVAVLGGPGPTRG--HHYCGSTRPPTLVSLGHELQVVF 237
Query: 248 STDYANSYRGFSASYTS 264
+D+ RGF A Y S
Sbjct: 238 KSDFNIGGRGFKAYYFS 254
Score = 92.4 bits (228), Expect = 1e-18
Identities = 63/213 (29%), Positives = 95/213 (44%), Gaps = 15/213 (7%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
S C W I ++++F Q++ + C + + V G GP G + P
Sbjct: 168 SMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVAVLGGP---GPTRGHHYCGSTRPP 224
Query: 115 VFESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPH 174
S L +D I F YYF C + G+F+SP YP +
Sbjct: 225 TLVSLGHELQVVFKSDF-NIGGRGFKAYYFSG------ECQEVYMAMRGNFSSPQYPSSY 277
Query: 175 PELAYCVWHIQVEKDYKIKLNFKEIFLE----IDKQCKFDFLAIYDGPSTNSGLIGQVCG 230
P C W I++ Y++K+ F ++ LE + K C FD LA +DG S + L+G CG
Sbjct: 278 PNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCG 337
Query: 231 -RVTPTFESSSNSLTVVLSTDYANSYRGFSASY 262
+ P SS N L ++L TD + + RGFS +Y
Sbjct: 338 HHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAY 370
>gi|13899255 membrane frizzled-related protein [Homo sapiens]
Length = 579
Score = 93.2 bits (230), Expect = 6e-19
Identities = 69/269 (25%), Positives = 119/269 (44%), Gaps = 47/269 (17%)
Query: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
P+ +C W I+ + +I++ + ++ SC + +++ GPLL +VC +
Sbjct: 166 PNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLEL--SPEPEGPLL-RVCGRVP-P 221
Query: 114 PVFESSSSTLTFQIVTDSARIQRTVFVFYYFFSP-------------------------- 147
P +++S L V+DS+ +Y +P
Sbjct: 222 PTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGSCAHDEFRCDQLICLLPDSVCDG 281
Query: 148 -------------NISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKL 194
+ CGG L L+G+F++P+Y + +P C WHI V + I+L
Sbjct: 282 FANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIEL 341
Query: 195 NFKEIFLEIDKQCKFDFLAIYDGPSTNS-GLIGQVCG-RVTPTFESSSNSLTVVLSTDYA 252
F LE +CKFD++ +Y+ S+ + L+G+ CG P SS + L V+ TD+
Sbjct: 342 QFHNFSLEAQDECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHG 401
Query: 253 NSYRGFSASYTSIYA-EN-INTTSLTCSS 279
S GFSA+Y + A EN + L+C +
Sbjct: 402 ISSGGFSATYLAFNATENPCGPSELSCQA 430
Score = 82.4 bits (202), Expect = 1e-15
Identities = 56/175 (32%), Positives = 84/175 (48%), Gaps = 10/175 (5%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG L G F+SPNYP P+P +CVWHIQV D+ I+L + + +E C FD L
Sbjct: 144 CGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLE 203
Query: 214 IYDGPSTNSGLIGQVCGRV-TPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINT 272
+ P G + +VCGRV PT ++++ L VV +D + GF A Y ++ +
Sbjct: 204 LSPEP---EGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGSC 260
Query: 273 TSLTCSSDRMRVIISKSYLEAF-----NSNGNNLQLKDPTCRPKLSNVV-EFSVP 321
D++ ++ S + F S+ N K C L+ + FS P
Sbjct: 261 AHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTP 315
>gi|4508045 zona pellucida glycoprotein 2 preproprotein [Homo
sapiens]
Length = 745
Score = 92.4 bits (228), Expect = 1e-18
Identities = 89/326 (27%), Positives = 142/326 (43%), Gaps = 38/326 (11%)
Query: 273 TSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPTCRP----KLSNVVEFSVPLNGCGTI 328
T C+ D + SY + L++ + +C+P + +V F +PLNGCGT
Sbjct: 368 TGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIPLNGCGTR 427
Query: 329 RKVEDQSITYTN-IITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYITEDDVIQSQ 387
K ED + Y N I I+R + ++ VKC N + I + +
Sbjct: 428 YKFEDDKVVYENEIHALWTDFPPSKISRDSEFRMTVKCSYSRNDMLLNINVESLTPPVAS 487
Query: 388 NALGKYNTSMALFESNSFEKTILESPYYV--DLNQTLFVQVS-LHTSDPNLVVFLDTCRA 444
LG + + + NS+++ E+ Y + L Q ++++V L+ DPN+ + LD C A
Sbjct: 488 VKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWA 547
Query: 445 SPTSDFAS-PTYDLIKSGCSRD---ETCKVYPLFG------HYGRFQFNAFKFLRS---- 490
+ T D S P ++++ GC+ D +P+ HY RF AF F+
Sbjct: 548 TSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVL 607
Query: 491 MSSVYLQCKVLICDS-SDHQSRCNQGC--VSRSKRDISSYKWK--TDSIIGPIRLKRDRS 545
S VY C LIC+ S C+ C SR +R + + + T S+ GPI L D S
Sbjct: 608 SSLVYFHCSALICNRLSPDSPLCSVTCPVSSRHRRATGATEAEKMTVSLPGPILLLSDDS 667
Query: 546 -----------ASGNSGFQHETHAEE 560
ASG+SG + + E
Sbjct: 668 SFRGVGSSDLKASGSSGEKSRSETGE 693
>gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens]
Length = 545
Score = 91.3 bits (225), Expect = 2e-18
Identities = 74/258 (28%), Positives = 119/258 (46%), Gaps = 18/258 (6%)
Query: 277 CSSDRMRVIISKSYLEAFNSNGNNLQLKDPTCRPKLSNV-VEFSVPLNGCGTIRKVEDQS 335
C S+ + V I + + G L L + +CR + V L CGT+ V +
Sbjct: 268 CKSNAIEVNIPRELV-----GGLELFLTNTSCRGVSNGTHVNILFSLKTCGTVVDVVNDK 322
Query: 336 ITYTNIITF----SASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI----TEDDVIQSQ 387
I +N++T + S+ + I R +L I V CE T+ Y+ I S+
Sbjct: 323 IVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNSPLEIMSR 382
Query: 388 NALGKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTSDPNLVVFLDTCRASPT 447
N G + ++ +F+ N FE+ E+ + L +L+ + L +++C A+PT
Sbjct: 383 NH-GIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESLVESCFATPT 441
Query: 448 SDFASPT-YDLIKSGCSRDETCKVYPLFGHYGR-FQFNAFKFL-RSMSSVYLQCKVLICD 504
S Y LI+ GC D++ K Y H + FQ FKF+ + V+L C+VL+C
Sbjct: 442 SKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCG 501
Query: 505 SSDHQSRCNQGCVSRSKR 522
D +SRC QGC R +R
Sbjct: 502 VLDERSRCAQGCHRRMRR 519
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 90.5 bits (223), Expect = 4e-18
Identities = 77/271 (28%), Positives = 117/271 (43%), Gaps = 12/271 (4%)
Query: 7 LMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPS-ENCTWTIERP 65
+ PLT + L+ + + C L + Q PS +NC W + P
Sbjct: 3 MFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAP 62
Query: 66 E-NKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLT 124
E N+ I + F+ C+ + I++ DG S + LLG+ C N P SS S L
Sbjct: 63 EPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCG-NIAPPTIISSGSMLY 121
Query: 125 FQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHI 184
+ +D AR + Y F +C + G+ SP +P+ +P C + I
Sbjct: 122 IKFTSDYARQGAGFSLRYEIFKTGSE--DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTI 179
Query: 185 QVEKDYKIKLNFKEIFLEIDK------QCKFDFLAIYDGPSTNSGLIGQVCGRVTPT-FE 237
+ +I L F LE D CK+D+L I+DG LIG+ CG TP+
Sbjct: 180 LAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELR 239
Query: 238 SSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
SS+ L++ TD A + GFSA Y ++ E
Sbjct: 240 SSTGILSLTFHTDMAVAKDGFSARYYLVHQE 270
Score = 83.2 bits (204), Expect = 6e-16
Identities = 57/150 (38%), Positives = 79/150 (52%), Gaps = 13/150 (8%)
Query: 138 VFVFYYFFSPNIS---IPNCGGYLDTLE-GSFTSPNYPKPHPELAYCVWHIQV-EKDYKI 192
VF+ YF + P CGG L++ + G TSP YP+ +P C W + E + KI
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 193 KLNFKEIFLEIDKQ-CKFDFLAIYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTD 250
LNF F EI+K CK+DF+ I DG S ++ L+G+ CG + PT SS + L + ++D
Sbjct: 69 VLNFNPHF-EIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 251 YANSYRGFSASYTSIYAENINTTSLTCSSD 280
YA GFS Y E T S CS +
Sbjct: 128 YARQGAGFSLRY-----EIFKTGSEDCSKN 152
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 90.5 bits (223), Expect = 4e-18
Identities = 77/271 (28%), Positives = 117/271 (43%), Gaps = 12/271 (4%)
Query: 7 LMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPS-ENCTWTIERP 65
+ PLT + L+ + + C L + Q PS +NC W + P
Sbjct: 3 MFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAP 62
Query: 66 E-NKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLT 124
E N+ I + F+ C+ + I++ DG S + LLG+ C N P SS S L
Sbjct: 63 EPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCG-NIAPPTIISSGSMLY 121
Query: 125 FQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHI 184
+ +D AR + Y F +C + G+ SP +P+ +P C + I
Sbjct: 122 IKFTSDYARQGAGFSLRYEIFKTGSE--DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTI 179
Query: 185 QVEKDYKIKLNFKEIFLEIDK------QCKFDFLAIYDGPSTNSGLIGQVCGRVTPT-FE 237
+ +I L F LE D CK+D+L I+DG LIG+ CG TP+
Sbjct: 180 LAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELR 239
Query: 238 SSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
SS+ L++ TD A + GFSA Y ++ E
Sbjct: 240 SSTGILSLTFHTDMAVAKDGFSARYYLVHQE 270
Score = 83.2 bits (204), Expect = 6e-16
Identities = 57/150 (38%), Positives = 79/150 (52%), Gaps = 13/150 (8%)
Query: 138 VFVFYYFFSPNIS---IPNCGGYLDTLE-GSFTSPNYPKPHPELAYCVWHIQV-EKDYKI 192
VF+ YF + P CGG L++ + G TSP YP+ +P C W + E + KI
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 193 KLNFKEIFLEIDKQ-CKFDFLAIYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTD 250
LNF F EI+K CK+DF+ I DG S ++ L+G+ CG + PT SS + L + ++D
Sbjct: 69 VLNFNPHF-EIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 251 YANSYRGFSASYTSIYAENINTTSLTCSSD 280
YA GFS Y E T S CS +
Sbjct: 128 YARQGAGFSLRY-----EIFKTGSEDCSKN 152
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 90.5 bits (223), Expect = 4e-18
Identities = 77/271 (28%), Positives = 117/271 (43%), Gaps = 12/271 (4%)
Query: 7 LMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPS-ENCTWTIERP 65
+ PLT + L+ + + C L + Q PS +NC W + P
Sbjct: 3 MFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAP 62
Query: 66 E-NKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLT 124
E N+ I + F+ C+ + I++ DG S + LLG+ C N P SS S L
Sbjct: 63 EPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCG-NIAPPTIISSGSMLY 121
Query: 125 FQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHI 184
+ +D AR + Y F +C + G+ SP +P+ +P C + I
Sbjct: 122 IKFTSDYARQGAGFSLRYEIFKTGSE--DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTI 179
Query: 185 QVEKDYKIKLNFKEIFLEIDK------QCKFDFLAIYDGPSTNSGLIGQVCGRVTPT-FE 237
+ +I L F LE D CK+D+L I+DG LIG+ CG TP+
Sbjct: 180 LAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELR 239
Query: 238 SSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
SS+ L++ TD A + GFSA Y ++ E
Sbjct: 240 SSTGILSLTFHTDMAVAKDGFSARYYLVHQE 270
Score = 83.2 bits (204), Expect = 6e-16
Identities = 57/150 (38%), Positives = 79/150 (52%), Gaps = 13/150 (8%)
Query: 138 VFVFYYFFSPNIS---IPNCGGYLDTLE-GSFTSPNYPKPHPELAYCVWHIQV-EKDYKI 192
VF+ YF + P CGG L++ + G TSP YP+ +P C W + E + KI
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 193 KLNFKEIFLEIDKQ-CKFDFLAIYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTD 250
LNF F EI+K CK+DF+ I DG S ++ L+G+ CG + PT SS + L + ++D
Sbjct: 69 VLNFNPHF-EIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 251 YANSYRGFSASYTSIYAENINTTSLTCSSD 280
YA GFS Y E T S CS +
Sbjct: 128 YARQGAGFSLRY-----EIFKTGSEDCSKN 152
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 90.5 bits (223), Expect = 4e-18
Identities = 77/271 (28%), Positives = 117/271 (43%), Gaps = 12/271 (4%)
Query: 7 LMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPS-ENCTWTIERP 65
+ PLT + L+ + + C L + Q PS +NC W + P
Sbjct: 3 MFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAP 62
Query: 66 E-NKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLT 124
E N+ I + F+ C+ + I++ DG S + LLG+ C N P SS S L
Sbjct: 63 EPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCG-NIAPPTIISSGSMLY 121
Query: 125 FQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHI 184
+ +D AR + Y F +C + G+ SP +P+ +P C + I
Sbjct: 122 IKFTSDYARQGAGFSLRYEIFKTGSE--DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTI 179
Query: 185 QVEKDYKIKLNFKEIFLEIDK------QCKFDFLAIYDGPSTNSGLIGQVCGRVTPT-FE 237
+ +I L F LE D CK+D+L I+DG LIG+ CG TP+
Sbjct: 180 LAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELR 239
Query: 238 SSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
SS+ L++ TD A + GFSA Y ++ E
Sbjct: 240 SSTGILSLTFHTDMAVAKDGFSARYYLVHQE 270
Score = 83.2 bits (204), Expect = 6e-16
Identities = 57/150 (38%), Positives = 79/150 (52%), Gaps = 13/150 (8%)
Query: 138 VFVFYYFFSPNIS---IPNCGGYLDTLE-GSFTSPNYPKPHPELAYCVWHIQV-EKDYKI 192
VF+ YF + P CGG L++ + G TSP YP+ +P C W + E + KI
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 193 KLNFKEIFLEIDKQ-CKFDFLAIYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTD 250
LNF F EI+K CK+DF+ I DG S ++ L+G+ CG + PT SS + L + ++D
Sbjct: 69 VLNFNPHF-EIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 251 YANSYRGFSASYTSIYAENINTTSLTCSSD 280
YA GFS Y E T S CS +
Sbjct: 128 YARQGAGFSLRY-----EIFKTGSEDCSKN 152
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 90.5 bits (223), Expect = 4e-18
Identities = 77/271 (28%), Positives = 117/271 (43%), Gaps = 12/271 (4%)
Query: 7 LMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPS-ENCTWTIERP 65
+ PLT + L+ + + C L + Q PS +NC W + P
Sbjct: 3 MFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAP 62
Query: 66 E-NKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLT 124
E N+ I + F+ C+ + I++ DG S + LLG+ C N P SS S L
Sbjct: 63 EPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCG-NIAPPTIISSGSMLY 121
Query: 125 FQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHI 184
+ +D AR + Y F +C + G+ SP +P+ +P C + I
Sbjct: 122 IKFTSDYARQGAGFSLRYEIFKTGSE--DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTI 179
Query: 185 QVEKDYKIKLNFKEIFLEIDK------QCKFDFLAIYDGPSTNSGLIGQVCGRVTPT-FE 237
+ +I L F LE D CK+D+L I+DG LIG+ CG TP+
Sbjct: 180 LAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELR 239
Query: 238 SSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
SS+ L++ TD A + GFSA Y ++ E
Sbjct: 240 SSTGILSLTFHTDMAVAKDGFSARYYLVHQE 270
Score = 83.2 bits (204), Expect = 6e-16
Identities = 57/150 (38%), Positives = 79/150 (52%), Gaps = 13/150 (8%)
Query: 138 VFVFYYFFSPNIS---IPNCGGYLDTLE-GSFTSPNYPKPHPELAYCVWHIQV-EKDYKI 192
VF+ YF + P CGG L++ + G TSP YP+ +P C W + E + KI
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 193 KLNFKEIFLEIDKQ-CKFDFLAIYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTD 250
LNF F EI+K CK+DF+ I DG S ++ L+G+ CG + PT SS + L + ++D
Sbjct: 69 VLNFNPHF-EIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 251 YANSYRGFSASYTSIYAENINTTSLTCSSD 280
YA GFS Y E T S CS +
Sbjct: 128 YARQGAGFSLRY-----EIFKTGSEDCSKN 152
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 90.5 bits (223), Expect = 4e-18
Identities = 77/271 (28%), Positives = 117/271 (43%), Gaps = 12/271 (4%)
Query: 7 LMPLTLLILSCLAELTMAEAEGNASCTVSLGGANMAETHKAMILQLNPS-ENCTWTIERP 65
+ PLT + L+ + + C L + Q PS +NC W + P
Sbjct: 3 MFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAP 62
Query: 66 E-NKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLT 124
E N+ I + F+ C+ + I++ DG S + LLG+ C N P SS S L
Sbjct: 63 EPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCG-NIAPPTIISSGSMLY 121
Query: 125 FQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHI 184
+ +D AR + Y F +C + G+ SP +P+ +P C + I
Sbjct: 122 IKFTSDYARQGAGFSLRYEIFKTGSE--DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTI 179
Query: 185 QVEKDYKIKLNFKEIFLEIDK------QCKFDFLAIYDGPSTNSGLIGQVCGRVTPT-FE 237
+ +I L F LE D CK+D+L I+DG LIG+ CG TP+
Sbjct: 180 LAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELR 239
Query: 238 SSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
SS+ L++ TD A + GFSA Y ++ E
Sbjct: 240 SSTGILSLTFHTDMAVAKDGFSARYYLVHQE 270
Score = 83.2 bits (204), Expect = 6e-16
Identities = 57/150 (38%), Positives = 79/150 (52%), Gaps = 13/150 (8%)
Query: 138 VFVFYYFFSPNIS---IPNCGGYLDTLE-GSFTSPNYPKPHPELAYCVWHIQV-EKDYKI 192
VF+ YF + P CGG L++ + G TSP YP+ +P C W + E + KI
Sbjct: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
Query: 193 KLNFKEIFLEIDKQ-CKFDFLAIYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTD 250
LNF F EI+K CK+DF+ I DG S ++ L+G+ CG + PT SS + L + ++D
Sbjct: 69 VLNFNPHF-EIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
Query: 251 YANSYRGFSASYTSIYAENINTTSLTCSSD 280
YA GFS Y E T S CS +
Sbjct: 128 YARQGAGFSLRY-----EIFKTGSEDCSKN 152
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 84.7 bits (208), Expect = 2e-16
Identities = 52/130 (40%), Positives = 67/130 (51%), Gaps = 7/130 (5%)
Query: 143 YFF--SPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIF 200
YF+ SP + I CGG L G SPN+P P+P C W I V DY I L F
Sbjct: 1535 YFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFS 1594
Query: 201 LEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFS 259
+E + +DFL IYDGP +NS LIG P ESSSN++ + +D + SY GF
Sbjct: 1595 IEPN----YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFH 1650
Query: 260 ASYTSIYAEN 269
Y + E+
Sbjct: 1651 LEYKAKLRES 1660
Score = 68.9 bits (167), Expect = 1e-11
Identities = 40/122 (32%), Positives = 62/122 (50%), Gaps = 8/122 (6%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG+ G SP +P + + C W I+ E + IK+ F+ E++ +D L
Sbjct: 855 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLE 910
Query: 214 IYDGPSTNSGLIGQVCGRVTPTF-ESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINT 272
++DGP+ S L+G G P F SSSN + ++ +TD + S GF Y S+ +NT
Sbjct: 911 VHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV---TVNT 967
Query: 273 TS 274
S
Sbjct: 968 YS 969
Score = 68.9 bits (167), Expect = 1e-11
Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Query: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNS 222
G SP YP +P L C W I VEK Y I + F E F + +FD L +YDGP+ S
Sbjct: 2427 GVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEFF---QTEKEFDVLQVYDGPNIQS 2482
Query: 223 GLIGQVCGRVTPTFESSSNSLTVVL--STDYANSYRGFSASYTSIY 266
++ + G + F +SN V L S D+ N+ +GF Y + Y
Sbjct: 2483 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 2528
Score = 63.9 bits (154), Expect = 4e-10
Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 151 IPNCGG-YLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKF 209
I CGG + G SP YP P+ C+W I+V+ + L F L D +
Sbjct: 1371 IAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQF----LAFDTEASH 1426
Query: 210 DFLAIYDGPSTNSGLIGQVCGRVTPT-FESSSNSLTVVLSTDYANSYRGFSASYTSIYA 267
D L ++DGP N L+ ++ G + P S+ N +T+ TD+ S GF+ ++S A
Sbjct: 1427 DILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1485
Score = 62.0 bits (149), Expect = 2e-09
Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 147 PNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQ 206
P +P CGG L +G+ SP YP+P+ CVW I V + I++ E +
Sbjct: 1893 PTCIVP-CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN-- 1949
Query: 207 CKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
+D L YDG N+ +G G P S+SN+L + +D + S GF YT+I
Sbjct: 1950 --WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2007
Score = 61.2 bits (147), Expect = 3e-09
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG + + G+ SP YP +P C W ++V I +N F + + +DF+
Sbjct: 2243 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYIN----FTVLQTEPIYDFIT 2298
Query: 214 IYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTDYANS 254
++DGP NS IGQ G + S+SN + + +D+ S
Sbjct: 2299 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS 2340
Score = 60.5 bits (145), Expect = 4e-09
Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 5/120 (4%)
Query: 151 IPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFD 210
I CGG L L G+ SP +P +P A C W I E+ +I++ F+ LE + +D
Sbjct: 22 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YD 77
Query: 211 FLAIYDGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAEN 269
+L++YDG + ++ G + P S+ + ++ L++D+A S GF Y + + +
Sbjct: 78 YLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSS 137
Score = 59.7 bits (143), Expect = 8e-09
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 5/103 (4%)
Query: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNS 222
G+ SP+YP+ + C+W I + +I L+F + LE +FDFLA+ DG S S
Sbjct: 690 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----SQFDFLAVKDGDSPES 745
Query: 223 GLIGQVCGRVTPT-FESSSNSLTVVLSTDYANSYRGFSASYTS 264
++G G P+ S+S+ L + D++ S RGF+ +Y +
Sbjct: 746 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 788
Score = 56.6 bits (135), Expect = 6e-08
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 19/188 (10%)
Query: 86 ESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFF 145
E EN K S G + C + DYV + ++T Q + + VF +
Sbjct: 451 EPENGKRIGSDFSLGSTVQFSCDE-DYVL---QGAKSITCQRIAE-------VFAAWSDH 499
Query: 146 SPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHI-QVEKDYKIKLNFKEIFLEID 204
P + CG L G+FTSPN+P + A CVW I V + I++NF+E LEI
Sbjct: 500 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG 559
Query: 205 KQCKFDFLAIYDGPSTNS--GLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSAS 261
+D L I DG ++ + G P S S+ + + L TD + GF +
Sbjct: 560 ----YDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 615
Query: 262 YTSIYAEN 269
Y I E+
Sbjct: 616 YKEIEKES 623
Score = 54.3 bits (129), Expect = 3e-07
Identities = 68/287 (23%), Positives = 114/287 (39%), Gaps = 79/287 (27%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
S +C WTI + I + F ++P+ + + ++DG SN PL+G ++ +P
Sbjct: 1571 SRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNSPLIGSF--QDSKLP 1624
Query: 115 V-FESSSSTLTFQIVTDS------------ARIQRTVF--------------------VF 141
ESSS+T+ +D A+++ + F V
Sbjct: 1625 ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVT 1684
Query: 142 YYFFSP---------------------NISIPNC----GGYLDTLEGSFTSPNYPKPHPE 176
YY + N ++P+C G EG+ SPNYPK +
Sbjct: 1685 YYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSV 1744
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLI----GQVCGRV 232
CV+ I V K++ + F +F + D + +YDGP+ S L+ G G
Sbjct: 1745 GHNCVYSIAVPKEFVVFGQF--VFFQTSLH---DVVEVYDGPTQQSSLLSSLSGSHSGES 1799
Query: 233 TPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSS 279
P SS N +T+ ++ + +GF Y ++ T+S CSS
Sbjct: 1800 LPL--SSGNQITIRFTSVGPITAKGFHFVYQAV----PRTSSTQCSS 1840
Score = 52.8 bits (125), Expect = 9e-07
Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 7/116 (6%)
Query: 151 IPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFD 210
+ CG EG SPNYP + C++ IQV+ I ++ + L + D
Sbjct: 1198 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-----AQGD 1252
Query: 211 FLAIYDGPSTNSGLIGQVCGRVTP--TFESSSNSLTVVLSTDYANSYRGFSASYTS 264
L IYDG + L+G G T S+SN L + ++D + GF YTS
Sbjct: 1253 VLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
Score = 52.8 bits (125), Expect = 9e-07
Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Query: 149 ISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCK 208
I + CGG + G SP +P +P C W I + + + L F+ +
Sbjct: 2066 ICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQ----FVNFSTETI 2121
Query: 209 FDFLAIYDGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASY 262
D+L + G S S +IG++ G ++ + S+++ ++ +DY+ + +GF Y
Sbjct: 2122 HDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY 2176
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 7/109 (6%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG + G +SP++P + A C W I E I L IF + + K+D+L
Sbjct: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL----IFTDFQMEEKYDYLE 256
Query: 214 IYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASY 262
I L G + P S+ N L + TD + YRGFSA Y
Sbjct: 257 IEGSEPPTIWLSGM---NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 47.8 bits (112), Expect = 3e-05
Identities = 59/273 (21%), Positives = 92/273 (33%), Gaps = 69/273 (25%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
S NC W IE SI+I F Q + + ++V DG + PLLG VP
Sbjct: 878 SLNCEWVIEAEPGHSIKITFERFQTE----LNYDVLEVHDGPNLLSPLLGSY--NGTQVP 931
Query: 115 VFESSSSTLTFQI-VTDSARIQRTVFVFYYFFSPNI------------------------ 149
F SSS + + TD++R + Y + N
Sbjct: 932 QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGST 991
Query: 150 ---------------------------SIPNC----GGYLDTLEGSFTSPNYPKPHPELA 178
+P C GG + G+ SP YP+ +P
Sbjct: 992 VSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSL 1051
Query: 179 YCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFES 238
C W + V ++ NF LE D+L I + S L + PT +
Sbjct: 1052 NCTWTVDVTHGKGVQFNFHTFHLE----DHHDYLLITENGSFTQPLARLTGSDLPPTINA 1107
Query: 239 ---SSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
+ + +D++ SY GF+ +++ E
Sbjct: 1108 GLYGNFRAQLRFISDFSISYEGFNITFSEYNLE 1140
Score = 35.0 bits (79), Expect = 0.20
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 4/68 (5%)
Query: 56 ENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPV 115
++C W + P I I F+ +Q +P + I V+DG N P +GQ V
Sbjct: 2267 QDCFWLVRVPPGNGIYINFTVLQTEPI----YDFITVWDGPDQNSPQIGQFSGNTALESV 2322
Query: 116 FESSSSTL 123
+ +S+ L
Sbjct: 2323 YSTSNQIL 2330
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 84.7 bits (208), Expect = 2e-16
Identities = 52/130 (40%), Positives = 67/130 (51%), Gaps = 7/130 (5%)
Query: 143 YFF--SPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIF 200
YF+ SP + I CGG L G SPN+P P+P C W I V DY I L F
Sbjct: 1471 YFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFS 1530
Query: 201 LEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFS 259
+E + +DFL IYDGP +NS LIG P ESSSN++ + +D + SY GF
Sbjct: 1531 IEPN----YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFH 1586
Query: 260 ASYTSIYAEN 269
Y + E+
Sbjct: 1587 LEYKAKLRES 1596
Score = 68.9 bits (167), Expect = 1e-11
Identities = 40/122 (32%), Positives = 62/122 (50%), Gaps = 8/122 (6%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG+ G SP +P + + C W I+ E + IK+ F+ E++ +D L
Sbjct: 791 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLE 846
Query: 214 IYDGPSTNSGLIGQVCGRVTPTF-ESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINT 272
++DGP+ S L+G G P F SSSN + ++ +TD + S GF Y S+ +NT
Sbjct: 847 VHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV---TVNT 903
Query: 273 TS 274
S
Sbjct: 904 YS 905
Score = 68.9 bits (167), Expect = 1e-11
Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Query: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNS 222
G SP YP +P L C W I VEK Y I + F E F + +FD L +YDGP+ S
Sbjct: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEFF---QTEKEFDVLQVYDGPNIQS 2418
Query: 223 GLIGQVCGRVTPTFESSSNSLTVVL--STDYANSYRGFSASYTSIY 266
++ + G + F +SN V L S D+ N+ +GF Y + Y
Sbjct: 2419 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 2464
Score = 63.9 bits (154), Expect = 4e-10
Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 151 IPNCGG-YLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKF 209
I CGG + G SP YP P+ C+W I+V+ + L F L D +
Sbjct: 1307 IAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQF----LAFDTEASH 1362
Query: 210 DFLAIYDGPSTNSGLIGQVCGRVTPT-FESSSNSLTVVLSTDYANSYRGFSASYTSIYA 267
D L ++DGP N L+ ++ G + P S+ N +T+ TD+ S GF+ ++S A
Sbjct: 1363 DILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1421
Score = 62.0 bits (149), Expect = 2e-09
Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 147 PNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQ 206
P +P CGG L +G+ SP YP+P+ CVW I V + I++ E +
Sbjct: 1829 PTCIVP-CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN-- 1885
Query: 207 CKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
+D L YDG N+ +G G P S+SN+L + +D + S GF YT+I
Sbjct: 1886 --WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1943
Score = 61.2 bits (147), Expect = 3e-09
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG + + G+ SP YP +P C W ++V I +N F + + +DF+
Sbjct: 2179 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYIN----FTVLQTEPIYDFIT 2234
Query: 214 IYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTDYANS 254
++DGP NS IGQ G + S+SN + + +D+ S
Sbjct: 2235 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS 2276
Score = 60.5 bits (145), Expect = 4e-09
Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 5/120 (4%)
Query: 151 IPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFD 210
I CGG L L G+ SP +P +P A C W I E+ +I++ F+ LE + +D
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YD 117
Query: 211 FLAIYDGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAEN 269
+L++YDG + ++ G + P S+ + ++ L++D+A S GF Y + + +
Sbjct: 118 YLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSS 177
Score = 59.7 bits (143), Expect = 8e-09
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 5/103 (4%)
Query: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNS 222
G+ SP+YP+ + C+W I + +I L+F + LE +FDFLA+ DG S S
Sbjct: 626 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----SQFDFLAVKDGDSPES 681
Query: 223 GLIGQVCGRVTPT-FESSSNSLTVVLSTDYANSYRGFSASYTS 264
++G G P+ S+S+ L + D++ S RGF+ +Y +
Sbjct: 682 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 724
Score = 56.6 bits (135), Expect = 6e-08
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 19/188 (10%)
Query: 86 ESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFF 145
E EN K S G + C + DYV + ++T Q + + VF +
Sbjct: 387 EPENGKRIGSDFSLGSTVQFSCDE-DYVL---QGAKSITCQRIAE-------VFAAWSDH 435
Query: 146 SPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHI-QVEKDYKIKLNFKEIFLEID 204
P + CG L G+FTSPN+P + A CVW I V + I++NF+E LEI
Sbjct: 436 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG 495
Query: 205 KQCKFDFLAIYDGPSTNS--GLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSAS 261
+D L I DG ++ + G P S S+ + + L TD + GF +
Sbjct: 496 ----YDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 551
Query: 262 YTSIYAEN 269
Y I E+
Sbjct: 552 YKEIEKES 559
Score = 54.3 bits (129), Expect = 3e-07
Identities = 68/287 (23%), Positives = 114/287 (39%), Gaps = 79/287 (27%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
S +C WTI + I + F ++P+ + + ++DG SN PL+G ++ +P
Sbjct: 1507 SRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNSPLIGSF--QDSKLP 1560
Query: 115 V-FESSSSTLTFQIVTDS------------ARIQRTVF--------------------VF 141
ESSS+T+ +D A+++ + F V
Sbjct: 1561 ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVT 1620
Query: 142 YYFFSP---------------------NISIPNC----GGYLDTLEGSFTSPNYPKPHPE 176
YY + N ++P+C G EG+ SPNYPK +
Sbjct: 1621 YYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSV 1680
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLI----GQVCGRV 232
CV+ I V K++ + F +F + D + +YDGP+ S L+ G G
Sbjct: 1681 GHNCVYSIAVPKEFVVFGQF--VFFQTSLH---DVVEVYDGPTQQSSLLSSLSGSHSGES 1735
Query: 233 TPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSS 279
P SS N +T+ ++ + +GF Y ++ T+S CSS
Sbjct: 1736 LPL--SSGNQITIRFTSVGPITAKGFHFVYQAV----PRTSSTQCSS 1776
Score = 52.8 bits (125), Expect = 9e-07
Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 7/116 (6%)
Query: 151 IPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFD 210
+ CG EG SPNYP + C++ IQV+ I ++ + L + D
Sbjct: 1134 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-----AQGD 1188
Query: 211 FLAIYDGPSTNSGLIGQVCGRVTP--TFESSSNSLTVVLSTDYANSYRGFSASYTS 264
L IYDG + L+G G T S+SN L + ++D + GF YTS
Sbjct: 1189 VLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1244
Score = 52.8 bits (125), Expect = 9e-07
Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Query: 149 ISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCK 208
I + CGG + G SP +P +P C W I + + + L F+ +
Sbjct: 2002 ICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQ----FVNFSTETI 2057
Query: 209 FDFLAIYDGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASY 262
D+L + G S S +IG++ G ++ + S+++ ++ +DY+ + +GF Y
Sbjct: 2058 HDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY 2112
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 7/109 (6%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG + G +SP++P + A C W I E I L IF + + K+D+L
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL----IFTDFQMEEKYDYLE 296
Query: 214 IYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASY 262
I L G + P S+ N L + TD + YRGFSA Y
Sbjct: 297 IEGSEPPTIWLSGM---NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 47.8 bits (112), Expect = 3e-05
Identities = 59/273 (21%), Positives = 92/273 (33%), Gaps = 69/273 (25%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
S NC W IE SI+I F Q + + ++V DG + PLLG VP
Sbjct: 814 SLNCEWVIEAEPGHSIKITFERFQTE----LNYDVLEVHDGPNLLSPLLGSY--NGTQVP 867
Query: 115 VFESSSSTLTFQI-VTDSARIQRTVFVFYYFFSPNI------------------------ 149
F SSS + + TD++R + Y + N
Sbjct: 868 QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGST 927
Query: 150 ---------------------------SIPNC----GGYLDTLEGSFTSPNYPKPHPELA 178
+P C GG + G+ SP YP+ +P
Sbjct: 928 VSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSL 987
Query: 179 YCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFES 238
C W + V ++ NF LE D+L I + S L + PT +
Sbjct: 988 NCTWTVDVTHGKGVQFNFHTFHLE----DHHDYLLITENGSFTQPLARLTGSDLPPTINA 1043
Query: 239 ---SSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
+ + +D++ SY GF+ +++ E
Sbjct: 1044 GLYGNFRAQLRFISDFSISYEGFNITFSEYNLE 1076
Score = 35.0 bits (79), Expect = 0.20
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 4/68 (5%)
Query: 56 ENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPV 115
++C W + P I I F+ +Q +P + I V+DG N P +GQ V
Sbjct: 2203 QDCFWLVRVPPGNGIYINFTVLQTEPI----YDFITVWDGPDQNSPQIGQFSGNTALESV 2258
Query: 116 FESSSSTL 123
+ +S+ L
Sbjct: 2259 YSTSNQIL 2266
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 84.7 bits (208), Expect = 2e-16
Identities = 52/130 (40%), Positives = 67/130 (51%), Gaps = 7/130 (5%)
Query: 143 YFF--SPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIF 200
YF+ SP + I CGG L G SPN+P P+P C W I V DY I L F
Sbjct: 1575 YFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFS 1634
Query: 201 LEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFS 259
+E + +DFL IYDGP +NS LIG P ESSSN++ + +D + SY GF
Sbjct: 1635 IEPN----YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFH 1690
Query: 260 ASYTSIYAEN 269
Y + E+
Sbjct: 1691 LEYKAKLRES 1700
Score = 68.9 bits (167), Expect = 1e-11
Identities = 40/122 (32%), Positives = 62/122 (50%), Gaps = 8/122 (6%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG+ G SP +P + + C W I+ E + IK+ F+ E++ +D L
Sbjct: 895 CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDVLE 950
Query: 214 IYDGPSTNSGLIGQVCGRVTPTF-ESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINT 272
++DGP+ S L+G G P F SSSN + ++ +TD + S GF Y S+ +NT
Sbjct: 951 VHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV---TVNT 1007
Query: 273 TS 274
S
Sbjct: 1008 YS 1009
Score = 68.9 bits (167), Expect = 1e-11
Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Query: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNS 222
G SP YP +P L C W I VEK Y I + F E F + +FD L +YDGP+ S
Sbjct: 2467 GVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEFF---QTEKEFDVLQVYDGPNIQS 2522
Query: 223 GLIGQVCGRVTPTFESSSNSLTVVL--STDYANSYRGFSASYTSIY 266
++ + G + F +SN V L S D+ N+ +GF Y + Y
Sbjct: 2523 PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 2568
Score = 63.9 bits (154), Expect = 4e-10
Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 151 IPNCGG-YLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKF 209
I CGG + G SP YP P+ C+W I+V+ + L F L D +
Sbjct: 1411 IAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQF----LAFDTEASH 1466
Query: 210 DFLAIYDGPSTNSGLIGQVCGRVTPT-FESSSNSLTVVLSTDYANSYRGFSASYTSIYA 267
D L ++DGP N L+ ++ G + P S+ N +T+ TD+ S GF+ ++S A
Sbjct: 1467 DILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVA 1525
Score = 62.0 bits (149), Expect = 2e-09
Identities = 39/120 (32%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 147 PNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQ 206
P +P CGG L +G+ SP YP+P+ CVW I V + I++ E +
Sbjct: 1933 PTCIVP-CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN-- 1989
Query: 207 CKFDFLAIYDGPSTNSGLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
+D L YDG N+ +G G P S+SN+L + +D + S GF YT+I
Sbjct: 1990 --WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2047
Score = 61.2 bits (147), Expect = 3e-09
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG + + G+ SP YP +P C W ++V I +N F + + +DF+
Sbjct: 2283 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYIN----FTVLQTEPIYDFIT 2338
Query: 214 IYDGPSTNSGLIGQVCGRVT-PTFESSSNSLTVVLSTDYANS 254
++DGP NS IGQ G + S+SN + + +D+ S
Sbjct: 2339 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS 2380
Score = 60.5 bits (145), Expect = 4e-09
Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 5/120 (4%)
Query: 151 IPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFD 210
I CGG L L G+ SP +P +P A C W I E+ +I++ F+ LE + +D
Sbjct: 62 IYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YD 117
Query: 211 FLAIYDGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAEN 269
+L++YDG + ++ G + P S+ + ++ L++D+A S GF Y + + +
Sbjct: 118 YLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSS 177
Score = 59.7 bits (143), Expect = 8e-09
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 5/103 (4%)
Query: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNS 222
G+ SP+YP+ + C+W I + +I L+F + LE +FDFLA+ DG S S
Sbjct: 730 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----SQFDFLAVKDGDSPES 785
Query: 223 GLIGQVCGRVTPT-FESSSNSLTVVLSTDYANSYRGFSASYTS 264
++G G P+ S+S+ L + D++ S RGF+ +Y +
Sbjct: 786 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 828
Score = 56.6 bits (135), Expect = 6e-08
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 19/188 (10%)
Query: 86 ESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFF 145
E EN K S G + C + DYV + ++T Q + + VF +
Sbjct: 491 EPENGKRIGSDFSLGSTVQFSCDE-DYVL---QGAKSITCQRIAE-------VFAAWSDH 539
Query: 146 SPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHI-QVEKDYKIKLNFKEIFLEID 204
P + CG L G+FTSPN+P + A CVW I V + I++NF+E LEI
Sbjct: 540 RPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIG 599
Query: 205 KQCKFDFLAIYDGPSTNS--GLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSAS 261
+D L I DG ++ + G P S S+ + + L TD + GF +
Sbjct: 600 ----YDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 655
Query: 262 YTSIYAEN 269
Y I E+
Sbjct: 656 YKEIEKES 663
Score = 54.3 bits (129), Expect = 3e-07
Identities = 68/287 (23%), Positives = 114/287 (39%), Gaps = 79/287 (27%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
S +C WTI + I + F ++P+ + + ++DG SN PL+G ++ +P
Sbjct: 1611 SRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNSPLIGSF--QDSKLP 1664
Query: 115 V-FESSSSTLTFQIVTDS------------ARIQRTVF--------------------VF 141
ESSS+T+ +D A+++ + F V
Sbjct: 1665 ERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVT 1724
Query: 142 YYFFSP---------------------NISIPNC----GGYLDTLEGSFTSPNYPKPHPE 176
YY + N ++P+C G EG+ SPNYPK +
Sbjct: 1725 YYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSV 1784
Query: 177 LAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLI----GQVCGRV 232
CV+ I V K++ + F +F + D + +YDGP+ S L+ G G
Sbjct: 1785 GHNCVYSIAVPKEFVVFGQF--VFFQTSLH---DVVEVYDGPTQQSSLLSSLSGSHSGES 1839
Query: 233 TPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTTSLTCSS 279
P SS N +T+ ++ + +GF Y ++ T+S CSS
Sbjct: 1840 LPL--SSGNQITIRFTSVGPITAKGFHFVYQAV----PRTSSTQCSS 1880
Score = 52.8 bits (125), Expect = 9e-07
Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 7/116 (6%)
Query: 151 IPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFD 210
+ CG EG SPNYP + C++ IQV+ I ++ + L + D
Sbjct: 1238 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-----AQGD 1292
Query: 211 FLAIYDGPSTNSGLIGQVCGRVTP--TFESSSNSLTVVLSTDYANSYRGFSASYTS 264
L IYDG + L+G G T S+SN L + ++D + GF YTS
Sbjct: 1293 VLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1348
Score = 52.8 bits (125), Expect = 9e-07
Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Query: 149 ISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCK 208
I + CGG + G SP +P +P C W I + + + L F+ +
Sbjct: 2106 ICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQ----FVNFSTETI 2161
Query: 209 FDFLAIYDGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASY 262
D+L + G S S +IG++ G ++ + S+++ ++ +DY+ + +GF Y
Sbjct: 2162 HDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY 2216
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 7/109 (6%)
Query: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLA 213
CGG + G +SP++P + A C W I E I L IF + + K+D+L
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL----IFTDFQMEEKYDYLE 296
Query: 214 IYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASY 262
I L G + P S+ N L + TD + YRGFSA Y
Sbjct: 297 IEGSEPPTIWLSGM---NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 47.8 bits (112), Expect = 3e-05
Identities = 59/273 (21%), Positives = 92/273 (33%), Gaps = 69/273 (25%)
Query: 55 SENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVP 114
S NC W IE SI+I F Q + + ++V DG + PLLG VP
Sbjct: 918 SLNCEWVIEAEPGHSIKITFERFQTE----LNYDVLEVHDGPNLLSPLLGSY--NGTQVP 971
Query: 115 VFESSSSTLTFQI-VTDSARIQRTVFVFYYFFSPNI------------------------ 149
F SSS + + TD++R + Y + N
Sbjct: 972 QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGST 1031
Query: 150 ---------------------------SIPNC----GGYLDTLEGSFTSPNYPKPHPELA 178
+P C GG + G+ SP YP+ +P
Sbjct: 1032 VSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSL 1091
Query: 179 YCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFES 238
C W + V ++ NF LE D+L I + S L + PT +
Sbjct: 1092 NCTWTVDVTHGKGVQFNFHTFHLE----DHHDYLLITENGSFTQPLARLTGSDLPPTINA 1147
Query: 239 ---SSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
+ + +D++ SY GF+ +++ E
Sbjct: 1148 GLYGNFRAQLRFISDFSISYEGFNITFSEYNLE 1180
Score = 35.0 bits (79), Expect = 0.20
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 4/68 (5%)
Query: 56 ENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPV 115
++C W + P I I F+ +Q +P + I V+DG N P +GQ V
Sbjct: 2307 QDCFWLVRVPPGNGIYINFTVLQTEPI----YDFITVWDGPDQNSPQIGQFSGNTALESV 2362
Query: 116 FESSSSTL 123
+ +S+ L
Sbjct: 2363 YSTSNQIL 2370
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,984,995
Number of Sequences: 37866
Number of extensions: 942729
Number of successful extensions: 2589
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 1935
Number of HSP's gapped (non-prelim): 383
length of query: 607
length of database: 18,247,518
effective HSP length: 108
effective length of query: 499
effective length of database: 14,157,990
effective search space: 7064837010
effective search space used: 7064837010
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.